Funktionelle Bildgebung zum kardiovaskulären Monitoring

Die Projektgruppe „funktionelle Bildgebung zum kardiovaskulären Monitoring“ beschäftigt sich mit der Entwicklung und Evaluation neuer Verfahren zur Visualisierung und Erfassung von Hämodynamik als auch Ventilation. Der Arbeitsschwerpunkt liegt gegenwärtig auf der Weiterentwicklung der Elektroimpedanztomographie (EIT) zur Detektion und Visualisierung der zentralen Hämodynamik. Perspektivisch lassen sich hierdurch vollkommen neue Techniken zur kontinuierlichen Überwachung und Therapiesteuerung von kritisch kranken Patienten entwickeln.

  • Projektleitung
  • Wissenschaftliche Mitarbeiter

    Dr. med Christoph Behem
    Dr. med. Till Friedheim
    Dr. med. Alexander März
    Dr. med. Annika Poppe
    Dr. med. Karin Wodack

  • Swisstom AG, Oregon Health and Science University,
    Portland, USA, Department of Systems and Computer Engineering,
    Carleton University, Ottawa, Canada

  • 1. Saugel B, Trepte CJ, Heckel K, Wagner JY, Reuter DA: Hemodynamic Management of Septic Shock: Is it Time for 'Individual Goal-Directed Hemodynamic Therapy' and for Specifically Targeting the Microcirculation? Shock 2015

    2. Wodack KH, Poppe AM, Tomkotter L, Bachmann KA, Strobel CM, Bonk S, Havel J, Heckel K, Gocht A, Saugel B, Mann O, Izbicki JR, Goetz AE, Trepte CJ, Reuter DA: Individualized early goal-directed therapy in systemic inflammation: is full utilization of preload reserve the optimal strategy? Crit Care Med 2014; 42: e741-51

    3. Nitzschke R, Wilgusch J, Kersten JF, Trepte CJ, Haas SA, Reuter DA, Goepfert MS: Bispectral index guided titration of sevoflurane in on-pump cardiac surgery reduces plasma sevoflurane concentration and vasopressor requirements: a prospective, controlled, sequential two-arm clinical study. Eur J Anaesthesiol 2014; 31: 482-90

    4. Zhai PW, Hu Y, Trepte CR, Winker DM, Josset DB, Lucker PL, Kattawar GW: Inherent optical properties of the coccolithophore: Emiliania huxleyi. Opt Express 2013; 21: 17625-38

    5. von Renteln D, Quaas A, Rosch T, Denzer UW, Szyrach MN, Enderle MD, Luth S, Haas S, Trepte C, Reutter D, Schachschal G: A novel flexible cryoprobe for EUS-guided pancreatic biopsies. Gastrointest Endosc 2013; 77: 784-92

    6. Trepte CJ, Haas SA, Nitzschke R, Salzwedel C, Goetz AE, Reuter DA: Prediction of volume-responsiveness during one-lung ventilation: a comparison of static, volumetric, and dynamic parameters of cardiac preload. J Cardiothorac Vasc Anesth 2013; 27: 1094-100

    7. Trepte CJ, Haas SA, Goepfert MS, Wagner FM, Reuter DA: Subtotal intracardiac fragmentation of a pulmonary artery catheter during cardiac surgery: a rare complication of bipolar atrial ablation. J Anesth 2013; 27: 147-8

    8. Trepte CJ, Eichhorn V, Haas SA, Stahl K, Schmid F, Nitzschke R, Goetz AE, Reuter DA: Comparison of an automated respiratory systolic variation test with dynamic preload indicators to predict fluid responsiveness after major surgery. Br J Anaesth 2013; 111: 736-42

    9. Trepte CJ, Bachmann KA, Stork JH, Friedheim TJ, Hinsch A, Goepfert MS, Mann O, Izbicki JR, Goetz AE, Reuter DA: The impact of early goal-directed fluid management on survival in an experimental model of severe acute pancreatitis. Intensive Care Med 2013; 39: 717-26

    10. Nitzschke R, Wilgusch J, Kersten JF, Trepte CJ, Haas SA, Reuter DA, Goetz AE, Goepfert MS: Changes in sevoflurane plasma concentration with delivery through the oxygenator during on-pump cardiac surgery. Br J Anaesth 2013; 110: 957-65

    11. Kober D, Trepte C, Petzoldt M, Nitzschke R, Herich L, Reuter DA, Haas S: Cardiac index assessment using bioreactance in patients undergoing cytoreductive surgery in ovarian carcinoma. J Clin Monit Comput 2013; 27: 621-7

    12. Haas SA, Trepte CJ, Nitzschke R, Jurgens TP, Goepfert MS, Goetz AE, Reuter DA: An assessment of global end-diastolic volume and extravascular lung water index during one-lung ventilation: is transpulmonary thermodilution usable? Anesth Analg 2013; 117: 83-90

    13. Bachmann KA, Trepte CJ, Tomkotter L, Hinsch A, Stork J, Bergmann W, Heidelmann L, Strate T, Goetz AE, Reuter DA, Izbicki JR, Mann O: Effects of thoracic epidural anesthesia on survival and microcirculation in severe acute pancreatitis: a randomized experimental trial. Crit Care 2013; 17: R281

    14. Trepte C, Haas S, Meyer N, Gebhardt M, Goepfert MS, Goetz AE, Reuter DA: Effects of one-lung ventilation on thermodilution-derived assessment of cardiac output. Br J Anaesth 2012; 108: 922-8

    15. Haas S, Trepte C, Hinteregger M, Fahje R, Sill B, Herich L, Reuter DA: Prediction of volume responsiveness using pleth variability index in patients undergoing cardiac surgery after cardiopulmonary bypass. J Anesth 2012; 26: 696-701

    16. Haas S, Eichhorn V, Hasbach T, Trepte C, Kutup A, Goetz AE, Reuter DA: Goal-directed fluid therapy using stroke volume variation does not result in pulmonary fluid overload in thoracic surgery requiring one-lung ventilation. Crit Care Res Pract 2012; 2012: 687018

    17. Trepte CJ, Eichhorn V, Haas SA, Richter HP, Goepfert MS, Kubitz JC, Goetz AE, Reuter DA: Thermodilution-derived indices for assessment of left and right ventricular cardiac function in normal and impaired cardiac function. Crit Care Med 2011; 39: 2106-12

    18. Haas S, Trepte C, Rybczynski M, Somville T, Treede H, Reuter DA: Type A aortic dissection during late pregnancy in a patient with Marfan syndrome. Can J Anaesth 2011; 58: 1024-8

    19. Eichhorn V, Trepte C, Richter HP, Kubitz JC, Goepfert MS, Goetz AE, Reuter DA: Respiratory systolic variation test in acutely impaired cardiac function for predicting volume responsiveness in pigs. Br J Anaesth 2011; 106: 659-64

    20. Luring C, Perlick L, Trepte C, Linhardt O, Perlick C, Plitz W, Grifka J: Micromotion in cemented rotating platform total knee arthroplasty: cemented tibial stem versus hybrid fixation. Arch Orthop Trauma Surg 2006; 126: 45-8

    21. Luring C, Bathis H, Oczipka F, Trepte C, Lufen H, Perlick L, Grifka J: Two-year follow-up on joint stability and muscular function comparing rotating versus fixed bearing TKR. Knee Surg Sports Traumatol Arthrosc 2006; 14: 605-11