Neue Publikation

Takahashi N, Oertner TG, Hegemann P, Larkum ME (2016) Active cortical dendrites modulate perception. Science 354: 1587-1590

Wiegert JS, Oertner TG (2016) How (not) to silence long-range projections with light. Nature Neuroscience 19, 527-528

Wietek J, Beltramo R, Scanziani M, Hegemann P, Oertner TG, Wiegert JS (2015) An improved chloride-conducting channelrhodopsin for light-induced inhibition of neuronal activity in vivo. Scientific Reports 5, 14807.

Scheib U, Stehfest K, Gee CE, Körschen HG, Fudim R, Oertner TG, Hegemann P (2015) The rhodopsin-guanylyl cyclase of the aquatic fungus Blastocladiella emersonii enables fast optical control of cGMP signaling. Science Signaling 8(389):rs8.

Blumer C, Vivien C, Genoud C, Perez-Alvarez A, Wiegert JS, Vetter T, Oertner TG (2015) Automated analysis of spine dynamics on live CA1 pyramidal cells. Medical Image Analysis 19(1):87-97.

Kanatsou S, Fearey BC, Kuil LE, Lucassen PJ, Harris AP, Seckl JR, Krugers H, Joels M (2015) Overexpression of Mineralocorticoid Receptors Partially Prevents Chronic Stress-Induced Reductions in Hippocampal Memory and Structural Plasticity. PLoS One 10(11):e0142012.

Behnke D, Cotesta S, Hintermann S, Fendt M, Gee CE, Jacobson LH, Laue G, Meyer A, Wagner T, Badiger S, Chaudhari V, Chebrolu M, Pandit C, Hoyer D, Betschart C (2015) Discovery of 1H-pyrazolo[3,4-b]pyridines as potent dual orexin receptor antagonists (DORAs). Bioorg Med Chem Lett. 25(23):5555-60.


The research group ‘Synaptic wiring and information processing’ (Head: Dr. J. Simon Wiegert) at the Center for Molecular Neurobiology Hamburg (ZMNH) invites applications for a position as

Postdoctoral Researcher (100% German TV-KAH scale 13)

The position is funded by the European Research Council (ERC) and initially available for 3 years, with the possibility of extension. The research group is a young team of international scientists. We are interested in questions regarding the role of synapses for information processing and memory storage in the mammalian brain. We combine state-of-the-art imaging techniques with optogenetic manipulation of identified synapses in hippocampal slice preparations and in vivo.

Job description: The successful applicant will work within the ERC funded project “LIFE synapses - Long-term Investigation of Functional Excitatory Synapses: Linking Plasticity, Network Wiring and Memory Storage”. The central aim of the project is to identify synapses participating in memory processes and to study their morphological stability and pre- and postsynaptic functional properties in vivo. The candidate will use mouse behavior, two-photon imaging, novel optogenetic approaches and molecular markers to investigate functional synapses in their native circuit over the time scale of weeks.

Your profile: We are looking for highly motivated applicants who hold a PhD in natural sciences. The project is focused on behavioral experiments combined with various optogenetic approaches and sophisticated, chronic 2-photon in vivo imaging in the mouse brain. Experience with mouse in vivo experiments and one of the above mentioned techniques is required. To efficiently handle the high end imaging techniques and complex data analysis a certain background in physics, biophysics and/or programming is advantageous.

Excellent communication skills and the ability to efficiently integrate in a multidisciplinary research team are expected.

Contact person: Dr. J. Simon Wiegert, email:, web:

We are looking forward to receiving your application, quoting the reference number 2017-46, including a motivation letter, your CV and PhD certificate, and the contact details of two referees via email to: or to the Universitätsklinikum Hamburg-Eppendorf, GB Personal, Recht & Organisation, Recruitment, Martinistr. 52, 20246 Hamburg, Germany until March 13th, 2017.

We offer equal opportunities, independent of age, sex, sexual identity, handicaps, country of

origin or religion; we have therefore signed the Charter of Diversity. In addition we support gender equality. We explicitly strive for a higher percentage of women in leading positions, especially

when it comes to our academic personal in research and development.

Women with equal qualification will be considered preferentially. The same applies to a low representation of a gender in the division which is calling for tender. Also will persons with a disability be considered preferentially in case of equal qualifications and skills.