Aktuelle Publikationen

Pecha S, Yorgan K, Röhl M, Geertz B, Hansen A, Weinberger F, Sehner S, Ehmke H, Reichenspurner H, Eschenhagen T, Schwoerer AP.
Human iPS cell-derived engineered heart tissue does not affect ventricular arrhythmias in a guinea pig cryo-injury model.
Sci Rep. 2019 Jul 8

Westhofen S, Jelinek M, Dreher L, Biermann D, Martin J, Vitzhum H, Reichenspurner H, Ehmke H, Schwoerer AP.
The heterotopic heart transplantation in mice as a small animal model to study mechanical unloading - Establishment of the procedure, perioperative management and postoperative scoring.
PLoS One. 2019 Apr 12

Schaefer A, Schneeberger Y, Schulz S, Krasemann S, Werner T, Piasecki A, Höppner G, Müller C, Morhenn K, Lorenz K, Wieczorek D, Schwoerer AP, Eschenhagen T, Ehmke H, Reichenspurner H, Stenzig J, Cuello F.
Analysis of fibrosis in control or pressure overloaded rat hearts after mechanical unloading by heterotopic heart transplantation.
Sci Rep. 2019 Apr 5

Gerlach DA, Manuel J, Hoff A, Kronsbein H, Hoffmann F, Heusser K, Ehmke H, Diedrich A, Jordan J, Tank J, Beissner F.
Novel Approach to Elucidate Human Baroreflex Regulation at the Brainstem Level: Pharmacological Testing During fMRI.
Front Neurosci. 2019 Mar 5

Rosendahl A, Kabiri R, Bode M, Cai A, Klinge S, Ehmke H, Mittrücker HW, Wenzel UO.
Adaptive immunity and IL-17A are not involved in the progression of chronic kidney disease after 5/6 nephrectomy in mice.
Br J Pharmacol. 2019 Jun;

Ehmke H.
The mechanotransduction of blood pressure.
Science. 2018 Oct 26

Ahadzadeh E, Rosendahl A, Czesla D, Steffens P, Prüßner L, Meyer-Schwesinger C, Wanner N, Paust HJ, Huber TB, Stahl RAK, Wiech T, Kurts C, Seniuk A, Ehmke H, Wenzel UO.
The chemokine receptor CX3CR1 reduces renal injury in mice with angiotensin II-induced hypertension.
Am J Physiol Renal Physiol. 2018 Dec

Schmiesing J, Storch S, Dörfler A, Schweizer M, Makrypidi-Fraune G, Thelen M, Sylvester M, Gieselmann V, Meyer-Schwesinger C, Koch-Nolte F, Tidow H, Mühlhausen C, Waheed A, Sly W, Braulke T
Disease-Linked Glutarylation Impairs Function and Interactions of Mitochondrial Proteins and Contributes to Mitochondrial Heterogeneity
CELL REP. 2018;24(11):2946-2956.

Jelinek M, Wallach C, Ehmke H, Schwoerer AP.
Genetic background dominates the susceptibility to ventricular arrhythmias in a murine model of β-adrenergic stimulation.
Sci Rep. 2018 Feb 2;8(1):2312

Bauer CK1, Schwarz JR2
Ether-à-go-go K+ channels: effective modulators of neuronal excitability.
J Physiol. 2018 Mar 1;596(5):769-783. doi: 10.1113/JP275477. Epub 2018 Feb 6.

Prechtel H, Hartmann S, Minge D, Bähring R.
Somatodendritic surface expression of epitope-tagged and KChIP binding-deficient Kv4.2 channels in hippocampal neurons.

PLoS One. 2018 Jan 31

Publikationen der letzten 10 Jahre

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Vor

Gain-of-Function Mutations in KCNN3 Encoding the Small-Conductance Ca2+-Activated K+ Channel SK3 Cause Zimmermann-Laband Syndrome
Bauer C, Schneeberger P, Kortüm F, Altmüller J, Santos-Simarro F, Baker L, Keller-Ramey J, White S, Campeau P, Gripp K, Kutsche K
AM J HUM GENET. 2019;104(6):1139-1157.

Endogenous IL-22 is dispensable for experimental glomerulonephritis
Gnirck A, Wunderlich M, Becker M, Xiong T, Weinert E, Meyer-Schwesinger C, Dumoutier L, Renauld J, Huber S, Panzer U, Turner J
AM J PHYSIOL-RENAL. 2019;316(4):F712-F722.

Thrombospondin Type 1 Domain-Containing 7A Localizes to the Slit Diaphragm and Stabilizes Membrane Dynamics of Fully Differentiated Podocytes
Herwig J, Skuza S, Sachs W, Sachs M, Failla A, Rune G, Meyer T, Fester L, Meyer-Schwesinger C
J AM SOC NEPHROL. 2019;30(5):824-839.

Isolation of Glomeruli and In Vivo Labeling of Glomerular Cell Surface Proteins
Königshausen E, Potthoff S, Haase R, Meyer-Schwesinger C, Kaufmann E, Rump L, Stegbauer J, Sellin L, Quack I, Woznowski M
JOVE-J VIS EXP. 2019;(143):.

Protecting the kidney against autoimmunity and inflammation
Kurts C, Meyer-Schwesinger C
NAT REV NEPHROL. 2019;15(2):66-68.

Human iPS cell-derived engineered heart tissue does not affect ventricular arrhythmias in a guinea pig cryo-injury model
Pecha S, Yorgan K, Röhl M, Geertz B, Hansen A, Weinberger F, Sehner S, Ehmke H, Reichenspurner H, Eschenhagen T, Schwoerer A
SCI REP-UK. 2019;9(1):9831.

Analysis of fibrosis in control or pressure overloaded rat hearts after mechanical unloading by heterotopic heart transplantation
Schaefer A, Schneeberger Y, Schulz S, Krasemann S, Werner T, Piasecki A, Höppner G, Müller C, Morhenn K, Lorenz K, Wieczorek D, Schwoerer A, Eschenhagen T, Ehmke H, Reichenspurner H, Stenzig J, Cuello F
SCI REP-UK. 2019;9(1):5710.

The heterotopic heart transplantation in mice as a small animal model to study mechanical unloading - Establishment of the procedure, perioperative management and postoperative scoring
Westhofen S, Jelinek M, Dreher L, Biermann D, Martin J, Vitzthum H, Reichenspurner H, Ehmke H, Schwoerer A
PLOS ONE. 2019;14(4):e0214513.

Augmentation of myocardial If dysregulates calcium homeostasis and causes adverse cardiac remodeling
Yampolsky P, Koenen M, Mosqueira M, Geschwill P, Nauck S, Witzenberger M, Seyler C, Fink T, Kruska M, Bruehl C, Schwoerer A, Ehmke H, Fink R, Draguhn A, Thomas D, Katus H, Schweizer P
NAT COMMUN. 2019;10(1):3295.

Kv channel-interacting proteins as neuronal and non-neuronal calcium sensors
Bähring R
CHANNELS. 2018;12(1):187-200.

Mutations in KCNK4 that Affect Gating Cause a Recognizable Neurodevelopmental Syndrome
Bauer C, Calligari P, Radio F, Caputo V, Dentici M, Falah N, High F, Pantaleoni F, Barresi S, Ciolfi A, Pizzi S, Bruselles A, Person R, Richards S, Cho M, Claps Sepulveda D, Pro S, Battini R, Zampino G, Digilio M, Bocchinfuso G, Dallapiccola B, Stella L, Tartaglia M
AM J HUM GENET. 2018;103(4):621-630.

Ether-à-go-go K+ channels: effective modulators of neuronal excitability
Bauer C, Schwarz J
J PHYSIOL-LONDON. 2018;596(5):769-783.

The mechanotransduction of blood pressure
Ehmke H
SCIENCE. 2018;362(6413):398-399.

Contractility of the epididymal duct: function, regulation and potential drug effects
Elfgen V, Mietens A, Mewe M, Hau T, Middendorff R
REPRODUCTION. 2018;156(4):R125–R141.

Genetic background dominates the susceptibility to ventricular arrhythmias in a murine model of β-adrenergic stimulation
Jelinek M, Wallach C, Ehmke H, Schwoerer A
SCI REP-UK. 2018;8(1):2312.

Role of Apolipoprotein L1 in Human Parietal Epithelial Cell Transition
Kumar V, Vashistha H, Lan X, Chandel N, Ayasolla K, Shoshtari S, Aslam R, Paliwal N, Abbruscato F, Mikulak J, Popik W, Atta M, Chander P, Malhotra A, Meyer-Schwesinger C, Skorecki K, Singhal P
AM J PATHOL. 2018;188(11):2508-2528.

Somatodendritic surface expression of epitope-tagged and KChIP binding-deficient Kv4.2 channels in hippocampal neurons
Prechtel H, Hartmann S, Minge D, Bähring R
PLOS ONE. 2018;13(1):e0191911.

Modulation of human Kv4.3/KChIP2 channel inactivation kinetics by cytoplasmic Ca²⁺
Groen C, Bähring R
PFLUG ARCH EUR J PHY. 2017;469(11):1457-1470.

KChIP2 genotype dependence of transient outward current (Ito) properties in cardiomyocytes isolated from male and female mice
Waldschmidt L, Junkereit V, Bähring R
PLOS ONE. 2017;12(1):e0171213.

A pathogenic role of complement in arterial hypertension and hypertensive end organ damage
Wenzel U, Bode M, Köhl J, Ehmke H
AM J PHYSIOL-HEART C. 2017;312(3):H349-H354.

Marine compound rhizochalinin shows high in vitro and in vivo efficacy in castration resistant prostate cancer
Dyshlovoy S, Otte K, Alsdorf W, Hauschild J, Lange T, Venz S, Bauer C, Bähring R, Amann K, Mandanchi R, Schumacher U, Schröder-Schwarz J, Makarieva T, Guzii A, Tabakmakher K, Fedorov S, Shubina L, Kasheverov I, Ehmke H, Steuber T, Stonik V, Bokemeyer C, Honecker F, von Amsberg G
ONCOTARGET. 2016;7(43):69703 - 69717.

Polyhydramnios, Transient Antenatal Bartter's Syndrome, and MAGED2 Mutations
Laghmani K, Beck B, Yang S, Seaayfan E, Wenzel A, Reusch B, Vitzthum H, Priem D, Demaretz S, Bergmann K, Duin L, Göbel H, Mache C, Thiele H, Bartram M, Dombret C, Altmüller J, Nürnberg P, Benzing T, Levtchenko E, Seyberth H, Klaus G, Yigit G, Lin S, Timmer A, de Koning T, Scherjon S, Schlingmann K, Bertrand M, Rinschen M, de Backer O, Konrad M, Kömhoff M
NEW ENGL J MED. 2016;374(19):1853-63.

Effects of Temperature on Heteromeric Kv11.1a/1b and Kv11.3 Channels
Mauerhöfer M, Bauer C
BIOPHYS J. 2016;111(3):504-23.

Nitrated fatty acids suppress angiotensin II-mediated fibrotic remodelling and atrial fibrillation
Rudolph T, Ravekes T, Klinke A, Friedrichs K, Mollenhauer M, Pekarova M, Ambrozova G, Martiskova H, Kaur J, Matthes B, Schwoerer A, Woodcock S, Kubala L, Freeman B, Baldus S, Rudolph V
CARDIOVASC RES. 2016;109(1):174-84.

A New Animal Model for Investigation of Mechanical Unloading in Hypertrophic and Failing Hearts: Combination of Transverse Aortic Constriction and Heterotopic Heart Transplantation
Schaefer A, Schneeberger Y, Stenzig J, Biermann D, Jelinek M, Reichenspurner H, Eschenhagen T, Ehmke H, Schwoerer A
PLOS ONE. 2016;11(2):e0148259.

The complement receptor C5aR1 contributes to renal damage but protects the heart in angiotensin II-induced hypertension
Weiss S, Rosendahl A, Czesla D, Meyer-Schwesinger C, Stahl R, Ehmke H, Kurts C, Zipfel P, Köhl J, Wenzel U
AM J PHYSIOL-RENAL. 2016;310(11):F1356-65.

Immune Mechanisms in Arterial Hypertension
Wenzel U, Turner J, Krebs C, Kurts C, Harrison D, Ehmke H
J AM SOC NEPHROL. 2016;27(3):677-86.

Intra- and Intersubunit Dynamic Binding in Kv4.2 Channel Closed-State Inactivation
Wollberg J, Bähring R
BIOPHYS J. 2016;110(1):157-75.

Regulation of vascular tone and arterial blood pressure: role of chloride transport in vascular smooth muscle
Hübner C, Schroeder B, Ehmke H
PFLUG ARCH EUR J PHY. 2015;467(3):605-14.

Mutations in KCNH1 and ATP6V1B2 cause Zimmermann-Laband syndrome
Kortüm F, Caputo V, Bauer C, Stella L, Ciolfi A, Alawi M, Bocchinfuso G, Flex E, Paolacci S, Dentici M, Grammatico P, Korenke G, Leuzzi V, Mowat D, Nair L, Nguyen T, Thierry P, White S, Dallapiccola B, Pizzuti A, Campeau P, Tartaglia M, Kutsche K
NAT GENET. 2015;47(6):661-7.

Regulation of the Na(+)-K(+)-2Cl(-) cotransporter by cGMP/cGMP-dependent protein kinase I after furosemide administration
Limmer F, Schinner E, Castrop H, Vitzthum H, Hofmann F, Schlossmann J
FEBS J. 2015;282(19):3786-98.

A Comparative Analysis of Bupivacaine and Ropivacaine Effects on Human Cardiac SCN5A Channels
Schwoerer A, Scheel H, Friederich P
ANESTH ANALG. 2015;120(6):1226-34.

Easy method to examine single nerve fiber excitability and conduction parameters using intact nonanesthetized earthworms
Bähring R, Bauer C
ADV PHYSIOL EDUC. 2014;38(3):253-64.

"Alkohol und Nikotin"-Konzept und Evaluation eines interdisziplinären Wahlfachs mit OSPE im Studienabschnitt Medizin 1
Bergelt C, Lauke-Wettwer H, Petersen-Ewert C, Jücker M, Bauer C
GMS J Med Educ. 2014;31(1):1-20.

Impaired sleep quality and sleep duration in smokers-results from the German Multicenter Study on Nicotine Dependence
Cohrs S, Rodenbeck A, Riemann D, Szagun B, Jaehne A, Brinkmeyer J, Gründer G, Wienker T, Diaz-Lacava A, Mobascher A, Dahmen N, Thuerauf N, Kornhuber J, Kiefer F, Gallinat J, Wagner M, Kunz D, Grittner U, Winterer G
ADDICT BIOL. 2014;19(3):486-96.

Converging genetic and functional brain imaging evidence links neuronal excitability to working memory, psychiatric disease, and brain activity
Heck A, Fastenrath M, Ackermann S, Auschra B, Bickel H, Coynel D, Gschwind L, Jessen F, Kaduszkiewicz H, Maier W, Milnik A, Pentzek M, Riedel-Heller S, Ripke S, Spalek K, Sullivan P, Vogler C, Wagner M, Weyerer S, Wolfsgruber S, de Quervain D, Papassotiropoulos A
NEURON. 2014;81(5):1203-13.

Disruption of vascular Ca2+-activated chloride currents lowers blood pressure
Heinze C, Seniuk A, Sokolov M, Huebner A, Klementowicz A, Szijártó I, Schleifenbaum J, Vitzthum H, Gollasch M, Ehmke H, Schroeder B, Hübner C
J CLIN INVEST. 2014;124(2):675-86.

Deficiency of the interleukin 17/23 axis accelerates renal injury in mice with deoxycorticosterone acetate+angiotensin ii-induced hypertension
Krebs C, Lange S, Niemann G, Rosendahl A, Lehners A, Meyer-Schwesinger C, Stahl R, Benndorf R, Velden J, Paust H, Panzer U, Ehmke H, Wenzel U
HYPERTENSION. 2014;63(3):565-71.

Myeloperoxidase deficiency ameliorates progression of chronic kidney disease in mice
Lehners A, Lange S, Niemann G, Rosendahl A, Meyer-Schwesinger C, Oh J, Stahl R, Ehmke H, Benndorf R, Klinke A, Baldus S, Wenzel U
AM J PHYSIOL-RENAL. 2014;307(4):F407-17.

Cardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivation
Mesirca P, Alig J, Torrente A, Müller J, Marger L, Rollin A, Marquilly C, Vincent A, Dubel S, Bidaud I, Fernandez A, Seniuk A, Engeland B, Singh J, Miquerol L, Ehmke H, Eschenhagen T, Nargeot J, Wickman K, Isbrandt D, Mangoni M
NAT COMMUN. 2014;5:4664.

Smooth muscle BK channel activity influences blood pressure independent of vascular tone in mice
Sachse G, Faulhaber J, Seniuk A, Ehmke H, Pongs O
J PHYSIOL-LONDON. 2014;592(Pt 12):2563-74.

Functional coupling of renal K+ and Na+ handling causes high blood pressure in Na+ replete mice
Vitzthum H, Seniuk A, Schulte L, Müller M, Hetz H, Ehmke H
J PHYSIOL-LONDON. 2014;592(Pt 5):1139-57.

Nedd4-2 regulates surface expression and may affect N-glycosylation of hyperpolarization-activated cyclic nucleotide-gated (HCN)-1 channels
Wilkars W, Wollberg J, Mohr E, Han M, Chetkovich D, Bähring R, Bender R
FASEB J. 2014;28(5):2177-90.

Parthenogenetic stem cells for tissue-engineered heart repair
Didié M, Christalla P, Rubart M, Muppala V, Döker S, Unsöld B, El-Armouche A, Rau T, Eschenhagen T, Schwoerer A, Ehmke H, Schumacher U, Fuchs S, Lange C, Becker A, Tao W, Scherschel J, Soonpaa M, Yang T, Lin Q, Zenke M, Han D, Schöler H, Rudolph C, Steinemann D, Schlegelberger B, Kattman S, Witty A, Keller G, Field L, Zimmermann W
J CLIN INVEST. 2013;123(3):1285-98.

Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signaling and arrhythmias in the heart evoked by β-adrenergic stimulation
Nebel M, Schwoerer A, Warszta D, Siebrands C, Limbrock A, Swarbrick J, Fliegert R, Weber K, Bruhn S, Hohenegger M, Geisler A, Herich L, Schlegel S, Carrier L, Eschenhagen T, Potter B, Ehmke H, Guse A
J BIOL CHEM. 2013;288(22):16017-30.

Baseline systolic left ventricular function determines hemodynamic adaptation following percutaneous mitral valve repair
Rudolph V, Moenig C, Lubos E, Kalbacher D, Knap M, Schlüter M, Kuß O, Koschyk D, Schwoerer A, Treede H, Schirmer J, Reichenspurner H, Ehmke H, Blankenberg S, Baldus S
INT J CARDIOL. 2013;167(6):3039-40.

Enhanced Ca²+ influx through cardiac L-type Ca²+ channels maintains the systolic Ca²+ transient in early cardiac atrophy induced by mechanical unloading
Schwoerer A, Neef S, Broichhausen I, Jacubeit J, Tiburcy M, Wagner M, Biermann D, Didié M, Vettel C, Maier L, Zimmermann W, Carrier L, Eschenhagen T, Volk T, El-Armouche A, Ehmke H
PFLUG ARCH EUR J PHY. 2013;465(12):1763-73.

Voltage sensor inactivation in potassium channels.
Bähring R, Barghaan J, Westermeier R, Wollberg J
FRONT PHARMACOL. 2012;3:100.

Impact of AT2 receptor deficiency on postnatal cardiovascular development.
Biermann D, Heilmann A, Didié M, Schlossarek S, Wahab A, Grimm M, Römer M, Reichenspurner H, Sultan K, Steenpass A, Ergün S, Donzelli S, Carrier L, Ehmke H, Zimmermann W, Hein L, Böger R, Benndorf R
PLOS ONE. 2012;7(10):47916.

Effects of the small molecule HERG activator NS1643 on Kv11.3 channels.
Bilet A, Bauer C
PLOS ONE. 2012;7(11):50886.

The sigma-1 receptor: a molecular chaperone for the heart and the soul?
Ehmke H
CARDIOVASC RES. 2012;93(1):6-7.

Compartment syndrome of the lower leg after punch biopsy.
Faulhaber J, Ehmke H, Koenen W, Weiss B, Goerdt S, Schneider S
DERMATOL SURG. 2012;38(2):277-278.

Inhibition of HERG1 K+ channel protein expression decreases cell proliferation of human small cell lung cancer cells.
Glassmeier G, Hempel K, Wulfsen I, Bauer C, Schumacher U, Schwarz J
PFLUG ARCH EUR J PHY. 2012;463(2):365-376.

Targeted mutation of SLC4A5 induces arterial hypertension and renal metabolic acidosis.
Gröger N, Vitzthum H, Fröhlich H, Krüger M, Ehmke H, Braun T, Boettger T
HUM MOL GENET. 2012;21(5):1025-1036.

Myeloperoxidase deficiency preserves vasomotor function in humans.
Rudolph T, Wipper S, Reiter B, Rudolph V, Coym A, Detter C, Lau D, Klinke A, Friedrichs K, Rau T, Pekarova M, Russ D, Knöll K, Stubendorff M, Schroeder B, Wegscheider K, Andresen H, Schwedhelm E, Böger R, Ehmke H, Baldus S
EUR HEART J. 2012;33(13):1625-1634.

Dimethylarginine dimethylaminohydrolase1 is an organ-specific mediator of end organ damage in a murine model of hypertension.
Sydow K, Schmitz C, von Leitner E, von Leitner R, Klinke A, Atzler D, Krebs C, Wieboldt H, Ehmke H, Schwedhelm E, Meinertz T, Blankenberg S, Böger R, Magnus T, Baldus S, Wenzel U
PLOS ONE. 2012;7(10):48150.

Aromatase inhibition abolishes LTP generation in female but not in male mice.
Vierk R, Glassmeier G, Zhou L, Brandt N, Fester L, Dudzinski D, Wilkars W, Bender R, Lewerenz M, Gloger S, Graser L, Schwarz J, Rune G
J NEUROSCI. 2012;32(24):8116-8126.

Localization of Islet-1-positive cells in the healthy and infarcted adult murine heart.
Weinberger F, Mehrkens D, Friedrich F, Stubendorff M, Hua X, Müller J, Schrepfer S, Evans S, Carrier L, Eschenhagen T
CIRC RES. 2012;110(10):1303-1310.

Inositol-1,4,5-trisphosphate 3-kinase A regulates dendritic morphology and shapes synaptic Ca2+ transients.
Windhorst S, Minge D, Bähring R, Hüser S, Schob C, Blechner C, Lin H, Mayr G, Kindler S
CELL SIGNAL. 2012;24(3):750-757.

Hippocampal A-type current and Kv4.2 channel modulation by the sulfonylurea compound NS5806.
Witzel K, Fischer P, Bähring R
NEUROPHARMACOLOGY. 2012;63(8):1389-1403.

Mechanisms of closed-state inactivation in voltage-gated ion channels.
Bähring R, Covarrubias M
J PHYSIOL-LONDON. 2011;589(3):461-479.

Selective attenuation of norepinephrine release and stress-induced heart rate increase by partial adenosine A1 agonism.
Bott-Flügel L, Bernshausen A, Schneider H, Luppa P, Zimmermann K, Albrecht-Küpper B, Kast R, Laugwitz K, Ehmke H, Knorr A, Seyfarth M
PLOS ONE. 2011;6(3):18048.

Expression pattern of Kv11 (Ether à-go-go-related gene; erg) K+ channels in the mouse retina.
Cordeiro S, Guseva D, Wulfsen I, Bauer C
PLOS ONE. 2011;6(12):29490.

Muskelin regulates actin filament- and microtubule-based GABA(A) receptor transport in neurons.
Heisler F, Löbrich S, Pechmann Y, Maier N, Zivkovic A, Tokito M, Hausrat T, Schweizer M, Bähring R, Holzbaur E, Schmitz D, Kneussel M
NEURON. 2011;70(1):66-81.

Myeloperoxidase attracts neutrophils by physical forces.
Klinke A, Nussbaum C, Kubala L, Friedrichs K, Rudolph T, Rudolph V, Paust H, Schröder C, Benten D, Lau D, Szöcs K, Furtmüller P, Heeringa P, Sydow K, Duchstein H, Ehmke H, Schumacher U, Meinertz T, Sperandio M, Baldus S
BLOOD. 2011;117(4):1350-1358.

Neuronal differentiation by indomethacin and IBMX inhibits proliferation of small cell lung cancer cells in vitro.
Lange A, Gustke H, Glassmeier G, Heine M, Zangemeister-Wittke U, Schwarz J, Schumacher U, Lange T
LUNG CANCER. 2011;74(2):178-187.

Functional roles of Ca(v)1.3, Ca(v)3.1 and HCN channels in automaticity of mouse atrioventricular cells: insights into the atrioventricular pacemaker mechanism.
Marger L, Mesirca P, Alig J, Torrente A, Dubel S, Engeland B, Kanani S, Fontanaud P, Striessnig J, Shin H, Isbrandt D, Ehmke H, Nargeot J, Mangoni M
CHANNELS. 2011;5(3):251-261.

Pacemaker activity and ionic currents in mouse atrioventricular node cells.
Marger L, Mesirca P, Alig J, Torrente A, Dubel S, Engeland B, Kanani S, Fontanaud P, Striessnig J, Shin H, Isbrandt D, Ehmke H, Nargeot J, Mangoni M
CHANNELS. 2011;5(3):241-250.

Acute alterations of somatodendritic action potential dynamics in hippocampal CA1 pyramidal cells after kainate-induced status epilepticus in mice.
Minge D, Bähring R
PLOS ONE. 2011;6(10):26664.

Strong activation of ether-à-go-go-related gene 1 K+ channel isoforms by NS1643 in human embryonic kidney 293 and Chinese hamster ovary cells.
Schuster A, Glassmeier G, Bauer C
MOL PHARMACOL. 2011;80(5):930-942.

Bupivacaine destabilizes action potential duration in cellular and computational models of long QT syndrome 1.
Schwoerer A, Zenouzi R, Ehmke H, Friederich P
ANESTH ANALG. 2011;113(6):1365-1373.

Pathogenic cycle between the endogenous nitric oxide synthase inhibitor asymmetrical dimethylarginine and the leukocyte-derived hemoprotein myeloperoxidase.
von Leitner E, Klinke A, Atzler D, Slocum J, Lund N, Kielstein J, Maas R, Schmidt-Haupt R, Pekarova M, Hellwinkel O, Tsikas D, D'Alecy L, Lau D, Willems S, Kubala L, Ehmke H, Meinertz T, Blankenberg S, Schwedhelm E, Gadegbeku C, Böger R, Baldus S, Sydow K
CIRCULATION. 2011;124(24):2735-2745.

Atmung
Ehmke H
2010. Duale Reihe: Physiologie. Georg Thieme Verlag: 224-267.

Säure-Basen-Haushalt
Ehmke H
2010. Duale Reihe: Physiologie. Georg Thieme Verlag: 268-289.

Common microRNA signatures in cardiac hypertrophic and atrophic remodeling induced by changes in hemodynamic load.
El-Armouche A, Schwoerer A, Neuber C, Emmons J, Biermann D, Christalla T, Grundhoff A, Eschenhagen T, Zimmermann W, Ehmke H
PLOS ONE. 2010;5(12):14263.

Medicinal leeches for the treatment of venous congestion and hematoma after plastic reconstructive surgery.
Friederike R, Koenen W, Goerdt S, Ehmke H, Faulhaber J
J DTSCH DERMATOL GES. 2010;8(11):881-888.

Development of a drug screening platform based on engineered heart tissue.
Hansen A, Eder A, Bönstrup M, Flato M, Mewe M, Schaaf S, Aksehirlioglu B, Schwoerer A, Uebeler J, Eschenhagen T
CIRC RES. 2010;107(1):35-44.

Gonadotropin-releasing hormone inhibits ether-à-go-go-related gene K+ currents in mouse gonadotropes.
Hirdes W, Dinu C, Bauer C, Boehm U, Schwarz J
ENDOCRINOLOGY. 2010;151(3):1079-1088.

Functional consequences of the interactions among the neural cell adhesion molecule NCAM, the receptor tyrosine kinase TrkB, and the inwardly rectifying K+ channel KIR3.3.
Kleene R, Cassens C, Bähring R, Theis T, Xiao M, Dityatev A, Schafer-Nielsen C, Döring F, Wischmeyer E, Schachner M
J BIOL CHEM. 2010;285(37):28968-28979.

Modulation of cardiac ERG1 K(+) channels by cGMP signaling.
Mewe M, Mauerhöfer M, Wulfsen I, Szlachta K, Zhou X, Schwarz J, Bauer C
J MOL CELL CARDIOL. 2010;49(1):48-57.

Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation.
Rudolph V, Andrié R, Rudolph T, Friedrichs K, Klinke A, Hirsch-Hoffmann B, Schwoerer A, Lau D, Fu X, Klingel K, Sydow K, Didié M, Seniuk A, von Leitner E, Szöcs K, Schrickel J, Treede H, Wenzel U, Lewalter T, Nickenig G, Zimmermann W, Meinertz T, Böger R, Reichenspurner H, Freeman B, Eschenhagen T, Ehmke H, Hazen S, Willems S, Baldus S
NAT MED. 2010;16(4):470-474.

The subtype-specific effects of droperidol on action potential duration in cellular and computational models of long QT syndrome.
Schwoerer A, Kebernik J, Ehmke H, Friederich P
ANESTH ANALG. 2010;111(3):638-646.

Molecular and functional remodeling of I(to) by angiotensin II in the mouse left ventricle
Tozakidou M, Goltz D, Hagenström T, Budack M, Vitzthum H, Szlachta K, Bähring R, Ehmke H
J MOL CELL CARDIOL. 2010;48(1):140-51.

Characterisation of the R276A gain-of-function mutation in the ectodomain of murine P2X7.
Adriouch S, Scheuplein F, Bähring R, Seman M, Boyer O, Koch Nolte F, Haag F
PURINERG SIGNAL. 2009;5(2):151-161.

Control of heart rate by cAMP sensitivity of HCN channels.
Alig J, Marger L, Mesirca P, Ehmke H, Mangoni M, Isbrandt D
P NATL ACAD SCI USA. 2009;106(29):12189-12194.

Dynamic coupling of voltage sensor and gate involved in closed-state inactivation of kv4.2 channels.
Barghaan J, Bähring R
J GEN PHYSIOL. 2009;133(2):205-224.

Angiotensin II type 2 receptor deficiency aggravates renal injury and reduces survival in chronic kidney disease in mice.
Benndorf R, Krebs C, Hirsch-Hoffmann B, Schwedhelm E, Cieslar G, Schmidt-Haupt R, Steinmetz O, Meyer-Schwesinger C, Thaiss F, Haddad M, Fehr S, Heilmann A, Helmchen U, Hein L, Ehmke H, Stahl R, Böger R, Wenzel U
KIDNEY INT. 2009;75(10):1039-1049.

Das Kreislaufsystem
Ehmke H
2009. Physiologie. Georg Thieme Verlag: 174-224.

Erg K+ currents modulate excitability in mouse mitral/tufted neurons.
Hirdes W, Napp N, Wulfsen I, Schweizer M, Schwarz J, Bauer C
PFLUG ARCH EUR J PHY. 2009;459(1):55-70.

Treatment with atorvastatin partially protects the rat heart from harmful catecholamine effects.
Schmechel A, Grimm M, El-Armouche A, Höppner G, Schwoerer A, Ehmke H, Eschenhagen T
CARDIOVASC RES. 2009;82(1):100-106.

Interaction of the human somatostatin receptor 3 with the multiple PDZ domain protein MUPP1 enables somatostatin to control permeability of epithelial tight junctions.
Vockel M, Liew C, Glassmeier G, Brandner J, Fernandez-Ballester G, Schwarz J, Schulz S, Buck F, Serrano L, Richter D, Kreienkamp H
FEBS LETT. 2009;583(1):49-54.

Larger transient outward K(+) current and shorter action potential duration in Galpha(11) mutant mice.
Wagner M, Rudakova E, Schütz V, Frank M, Ehmke H, Volk T
PFLUG ARCH EUR J PHY. 2009.

Role of N-terminal domain and accessory subunits in controlling deactivation-inactivation coupling of Kv4.2 channels.
Barghaan J, Tozakidou M, Ehmke H, Bähring R
BIOPHYS J. 2008;94(4):1276-1294.

The hnRNP and cytoskeletal protein raver1 contributes to synaptic plasticity.
Lahmann I, Fabienke M, Henneberg B, Pabst O, Vauti F, Minge D, Illenberger S, Jockusch B, Korte M, Arnold H
EXP CELL RES. 2008;314(5):1048-1060.

Erg K+ channels modulate contractile activity in the bovine epididymal duct.
Mewe M, Wulfsen I, Schuster A, Middendorff R, Glassmeier G, Schwarz J, Bauer C
AM J PHYSIOL-REG I. 2008;294(3):895-904.

Design and synthesis of potent and selective azaindole-based Rho kinase (ROCK) inhibitors.
Schirok H, Kast R, Figueroa-Pérez S, Bennabi S, Gnoth M, Feurer A, Heckroth H, Thutewohl M, Paulsen H, Knorr A, Hütter J, Lobell M, Münter K, Geiss V, Ehmke H, Lang D, Radtke M, Mittendorf J, Stasch J
CHEMMEDCHEM. 2008;3(12):1893-1904.

Unloaded rat hearts in vivo express a hypertrophic phenotype of cardiac repolarization.
Schwoerer A, Melnychenko I, Goltz D, Hedinger N, Broichhausen I, El-Armouche A, Eschenhagen T, Volk T, Ehmke H
J MOL CELL CARDIOL. 2008;45(5):633-641.

Mechanical unloading of the rat heart involves marked changes in the protein kinase-phosphatase balance.
Schwoerer A, Neuber C, Schmechel A, Melnychenko I, Mearini G, Boknik P, Kirchhefer U, Schmitz W, Ehmke H, Eschenhagen T, El-Armouche A
J MOL CELL CARDIOL. 2008;45(6):846-852.

Functional characterization of genetically labeled gonadotropes.
Wen S, Schwarz J, Niculescu D, Dinu C, Bauer C, Hirdes W, Boehm U
ENDOCRINOLOGY. 2008;149(6):2701-2711.

Modulation of Ca2+ entry and plasma membrane potential by human TRPM4b.
Fliegert R, Glassmeier G, Schmid F, Cornils K, Genisyuerek S, Harneit A, Schwarz J, Guse A
FEBS J. 2007;274(3):704-713.

Diminished Kv4.2/3 but not KChIP2 levels reduce the cardiac transient outward K+ current in spontaneously hypertensive rats.
Goltz D, Schultz J, Stucke C, Wagner M, Bassalaý P, Schwoerer A, Ehmke H, Volk T
CARDIOVASC RES. 2007;74(1):85-95.

Cardiovascular effects of a novel potent and highly selective azaindole-based inhibitor of Rho-kinase.
Kast R, Schirok H, Figueroa-Pérez S, Mittendorf J, Gnoth M, Apeler H, Lenz J, Franz J, Knorr A, Hütter J, Lobell M, Zimmermann K, Münter K, Augstein K, Ehmke H, Stasch J
BRIT J PHARMACOL. 2007;152(7):1070-1080.

Differential modulation of bovine epididymal activity by oxytocin and noradrenaline.
Mewe M, Wulfsen I, Middendorff R, Bauer C
REPRODUCTION. 2007;134(3):493-501.

Molecular and functional characterization of Kv4.2 and KChIP2 expressed in the porcine left ventricle.
Schultz J, Volk T, Bassalaý P, Hennings J, Hübner C, Ehmke H
PFLUG ARCH EUR J PHY. 2007;454(2):195-207.

Molecular interaction of droperidol with human ether-a-go-go-related gene channels: prolongation of action potential duration without inducing early afterdepolarization.
Schwoerer A, Blütner C, Brandt S, Binder S, Siebrands C, Ehmke H, Friederich P
ANESTHESIOLOGY. 2007;106(5):967-976.

The podocyte-specific inactivation of Lmx1b, Ldb1 and E2a yields new insight into a transcriptional network in podocytes.
Suleiman H, Heudobler D, Raschta A, Zhao Y, Zhao Q, Hertting I, Vitzthum H, Moeller M, Holzman L, Rachel R, Johnson R, Westphal H, Rascle A, Witzgall R
DEV BIOL. 2007;304(2):701-712.

Modulation of the transient outward K+ current by inhibition of endothelin-A receptors in normal and hypertrophied rat hearts.
Wagner M, Goltz D, Stucke C, Schwoerer A, Ehmke H, Volk T
PFLUG ARCH EUR J PHY. 2007;454(4):595-604.

C-terminal HERG (LQT2) mutations disrupt IKr channel regulation through 14-3-3epsilon.
Choe C, Schulze-Bahr E, Neu A, Xu J, Zhu Z, Sauter K, Bähring R, Priori S, Guicheney P, Mönnig G, Neapolitano C, Heidemann J, Clancy C, Pongs O, Isbrandt D
HUM MOL GENET. 2006;15(19):2888-2902.

Activation of T cell calcium influx by the second messenger ADP-ribose.
Gasser A, Glassmeier G, Fliegert R, Langhorst M, Meinke S, Hein D, Krüger S, Weber K, Heiner I, Oppenheimer N, Schwarz J, Guse A
J BIOL CHEM. 2006;281(5):2489-2496.

Activated radixin is essential for GABAA receptor alpha5 subunit anchoring at the actin cytoskeleton.
Loebrich S, Bähring R, Katsuno T, Tsukita S, Kneussel M
EMBO J. 2006;25(5):987-999.

The neuropeptide head activator is a high-affinity ligand for the orphan G-protein-coupled receptor GPR37.
Rezgaoui M, Süsens U, Ignatov A, Gelderblom M, Glassmeier G, Franke I, Urny J, Imai Y, Takahashi R, Schaller H
J CELL SCI. 2006;119(3):542-549.

KCNQ channels mediate IKs, a slow K+ current regulating excitability in the rat node of Ranvier.
Schwarz J, Glassmeier G, Cooper E, Kao T, Nodera H, Tabuena D, Kaji R, Bostock H
J PHYSIOL-LONDON. 2006;573(1):17-34.

Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts.
Zimmermann W, Melnychenko I, Wasmeier G, Didié M, Naito H, Nixdorff U, Hess A, Budinsky L, Brune K, Michaelis B, Dhein S, Schwoerer A, Ehmke H, Eschenhagen T
NAT MED. 2006;12(4):452-458.

Contribution of N- and C-terminal Kv4.2 channel domains to KChIP interaction [corrected]
Callsen B, Isbrandt D, Sauter K, Hartmann L, Pongs O, Bähring R
J PHYSIOL-LONDON. 2005;568(2):397-412.

Differential modulation of Kv1 channel-mediated currents by co-expression of Kvbeta3 subunit in a mammalian cell-line.
Bähring R, Vardanyan V, Pongs O
MOL MEMBR BIOL. 2004;21(1):19-25.

Modulation of Kv4.2 channels by a peptide isolated from the venom of the giant bird-eating tarantula Theraphosa leblondi.
Ebbinghaus J, Legros C, Nolting A, Guette C, Celerier M, Pongs O, Bähring R
TOXICON. 2004;43(8):923-932.

N-type inactivation features of Kv4.2 channel gating.
Gebauer M, Isbrandt D, Sauter K, Callsen B, Nolting A, Pongs O, Bähring R
BIOPHYS J. 2004;86(1 Pt 1):210-223.

Clinical and electrophysiological characterization of a novel mutation R863X in HERG C-terminus associated with long QT syndrome.
Teng S, Ma L, Dong Y, Lin C, Ye J, Bähring R, Vardanyan V, Yang Y, Lin Z, Pongs O, Hui R
J MOL MED. 2004;82(3):189-196.

HERG K(+) currents in human prolactin-secreting adenoma cells.
Bauer C, Wulfsen I, Schäfer R, Glassmeier G, Wimmers S, Flitsch J, Lüdecke D, Schwarz J
PFLUG ARCH EUR J PHY. 2003;445(5):589-600.

Characterization of a novel Long QT syndrome mutation G52R-KCNE1 in a Chinese family.
Ma L, Lin C, Teng S, Chai Y, Bähring R, Vardanyan V, Li L, Pongs O, Hui R
CARDIOVASC RES. 2003;59(3):612-619.

Novel gene hKCNE4 slows the activation of the KCNQ1 channel.
Teng S, Ma L, Zhen Y, Lin C, Bähring R, Vardanyan V, Pongs O, Hui R
BIOCHEM BIOPH RES CO. 2003;303(3):808-813.

A polycystin-2-like large conductance cation channel in rat left ventricular myocytes.
Volk T, Schwoerer A, Thiessen S, Schultz J, Ehmke H
CARDIOVASC RES. 2003;58(1):76-88.

Kinetic analysis of open- and closed-state inactivation transitions in human Kv4.2 A-type potassium channels.
Bähring R, Boland L, Varghese A, Gebauer M, Pongs O
J PHYSIOL-LONDON. 2001;535(1):65-81.

Conserved Kv4 N-terminal domain critical for effects of Kv channel-interacting protein 2.2 on channel expression and gating.
Bähring R, Dannenberg J, Peters H, Leicher T, Pongs O, Isbrandt D
J BIOL CHEM. 2001;276(26):23888-23894.

Coupling of voltage-dependent potassium channel inactivation and oxidoreductase active site of Kvbeta subunits.
Bähring R, Milligan C, Vardanyan V, Engeland B, Young B, Dannenberg J, Waldschutz R, Edwards J, Wray D, Pongs O
J BIOL CHEM. 2001;276(25):22923-22929.

The neuropeptide head activator induces activation and translocation of the growth-factor-regulated Ca(2+)-permeable channel GRC.
Boels K, Glassmeier G, Herrmann D, Riedel I, Hampe W, Kojima I, Schwarz J, Schaller H
J CELL SCI. 2001;114(20):3599-3606.

Ca2+ channels in clonal rat anterior pituitary cells (GH3/B6).
Glassmeier G, Hauber M, Wulfsen I, Weinsberg F, Bauer C, Schwarz J
PFLUG ARCH EUR J PHY. 2001;442(4):577-587.

Block of AMPA and Kainate Receptors by Polyamines and Arthropod Toxins
Bowie D, Bähring R, Mayer M
1999. Handbook of Experimental Pharmacology. Jonas P, Monyer H (Hrsg.). 1.. Aufl. Springer-Verlag, Berlin, 251 - 373.

Functional and molecular aspects of voltage-gated K+ channel beta subunits.
Pongs O, Leicher T, Berger M, Roeper J, Bähring R, Wray D, Giese K, Silva A, Storm J
ANN NY ACAD SCI. 1999;868:344-355.

Repetitive firing deficits and reduced sodium current density in retinal ganglion cells developing in the absence of BDNF.
Rothe T, Bähring R, Carroll P, Grantyn R
J NEUROBIOL. 1999;40(3):407-419.

Ion conductances related to development of repetitive firing in mouse retinal ganglion neurons in situ.
Rothe T, Jüttner R, Bähring R, Grantyn R
J NEUROBIOL. 1999;38(2):191-206.

An analysis of philanthotoxin block for recombinant rat GluR6(Q) glutamate receptor channels.
Bähring R, Mayer M
J PHYSIOL-LONDON. 1998;509(3):635-650.

The role of hydrophobic interactions in binding of polyamines to non NMDA receptor ion channels.
Cu C, Bähring R, Mayer M, Cui C
NEUROPHARMACOLOGY. 1998;37(10-11):1381-1391.

Expression of functional GABAA receptors in cholecystokinin-secreting gut neuroendocrine murine STC-1 cells.
Glassmeier G, Herzig K, Höpfner M, Lemmer K, Jansen A, Scherubl H
J PHYSIOL-LONDON. 1998;510(3):805-814.

Expression of functional GABAA receptors in isolated human insulinoma cells.
Glassmeier G, Höpfner M, Buhr H, Lemmer K, Riecken E, Stein H, Quabbe H, Rancso C, Wiedenmann B, Scherübl H
ANN NY ACAD SCI. 1998;859:241-248.

Inhibition of L-type calcium channels by octreotide in isolated human neuroendocrine tumor cells of the gut.
Glassmeier G, Höpfner M, Riecken E, Mann B, Buhr H, Neuhaus P, Meyerhof W, Scherübl H
BIOCHEM BIOPH RES CO. 1998;250(2):511-515.

Inhibition of L-type calcium channels by somatostatins in human neuroendocrine tumor cells of the gut.
Glassmeier G, Höpfner M, Riecken E, Mann B, Buhr H, Neuhaus P, Wiedenmann B, Scherübl H
ANN NY ACAD SCI. 1998;859:208-209.

Expression of functional P2-purinergic receptors in primary cultures of human colorectal carcinoma cells.
Höpfner M, Lemmer K, Jansen A, Hanski C, Riecken E, Gavish M, Mann B, Buhr H, Glassmeier G, Scherübl H
BIOCHEM BIOPH RES CO. 1998;251(3):811-817.

Coexpression of the KCNA3B gene product with Kv1.5 leads to a novel A-type potassium channel.
Leicher T, Bähring R, Isbrandt D, Pongs O
J BIOL CHEM. 1998;273(52):35095-35101.

A somatostatin receptor 1 selective ligand inhibits Ca2+ currents in rat insulinoma 1046-38 cells.
Roosterman D, Glassmeier G, Baumeister H, Scherübl H, Meyerhof W
FEBS LETT. 1998;425(1):137-140.

Permeation and block of rat GluR6 glutamate receptor channels by internal and external polyamines.
Bähring R, Bowie D, Benveniste M, Mayer M
J PHYSIOL-LONDON. 1997;502(3):575-589.

Electrophysiological properties of human carcinoid cells of the gut.
Glassmeier G, Strübing C, Riecken E, Buhr H, Neuhaus P, Ahnert-Hilger G, Wiedenmann B, Scherübl H
GASTROENTEROLOGY. 1997;113(1):90-100.

AMPA receptor heterogeneity in rat hippocampal neurons revealed by differential sensitivity to cyclothiazide.
Fleck M, Bähring R, Patneau D, Mayer M
J NEUROPHYSIOL. 1996;75(6):2322-2333.

Changes in ion channel expression during in vitro differentiation of trout oligodendrocyte precursor cells.
Glassmeier G, Jeserich G
GLIA. 1995;15(1):83-93.

Differential modulation by sulfhydryl redox agents and glutathione of GABA- and glycine-evoked currents in rat retinal ganglion cells.
Pan Z, Bähring R, Grantyn R, Lipton S
J NEUROSCI. 1995;15(2):1384-1391.

Unilateral ablation of the frontal eye field of the rat affects the beating field of ocular nystagmus.
Bähring R, Meier R, Dieringer N
EXP BRAIN RES. 1994;98(3):391-400.

GABA-activated chloride currents of postnatal mouse retinal ganglion cells are blocked by acetylcholine and acetylcarnitine: how specific are ion channels in immature neurons?
Bähring R, Standhardt H, Martelli E, Grantyn R
EUR J NEUROSCI. 1994;6(7):1089-1099.

Voltage-dependent sodium and potassium currents in cultured trout astrocytes.
Glassmeier G, Jeserich G, Krüppel T
GLIA. 1994;11(3):245-254.

Voltage-dependent potassium currents in cultured trout oligodendrocytes.
Glassmeier G, Jeserich G, Krüppel T
J NEUROSCI RES. 1992;32(3):301-308.

A rat pituitary tumour K+ channel expressed in frog oocytes induces a transient K+ current indistinguishable from that recorded in native cells
Meyerhof W, Schwarz J, Bauer C, Hübel A, Richter D
J NEUROENDOCRINOL. 1992;4(2):245-53.

Letzte Aktualisierung aus dem FIS: 23.09.2019 - 00:34 Uhr