Aktuelle Publikationen

Groen C, Bähring R.
Modulation of human Kv4.3/KChIP2 channel inactivation kinetics by cytoplasmic Ca²⁺.
Pflugers Arch. 2017 Jul 22

Waldschmidt L, Junkereit V, Bähring R.
KChIP2 genotype dependence of transient outward current (Ito) properties in cardiomyocytes isolated from male and female mice.
PLoS One. 2017 Jan

Wenzel UO, Bode M, Köhl J, Ehmke H.
A pathogenic role of complement in arterial hypertension and hypertensive end organ damage.
Am J Physiol Heart Circ Physiol. 2016 Dec 16

Dyshlovoy SA, Otte K, Alsdorf WH, Hauschild J, Lange T, Venz S, Bauer CK, Bähring R, Amann K, Mandanchi R, Schumacher U, Schröder-Schwarz J, Makarieva TN, Guzii AG, Tabakmakher KM, Fedorov SN, Shubina LK, Kasheverov IE, Ehmke H, Steuber T, Stonik VA, Bokemeyer C, Honecker F, von Amsberg G.
Marine compound rhizochalinin shows high in vitro and in vivo efficacy in castration resistant prostate cancer.
Oncotarget. 2016 Oct 25;

Mauerhöfer M, Bauer CK.
Effects of Temperature on Heteromeric Kv11.1a/1b and Kv11.3 Channels.
Biophys J. 2016 Aug 9 ;

Weiss S, Rosendahl A, Czesla D, Meyer-Schwesinger C, Stahl RA, Ehmke H, Kurts C, Zipfel PF, Köhl J, Wenzel UO.
The complement receptor C5aR1 contributes to renal damage but protects the heart in angiotensin II-induced hypertension.
Am J Physiol Renal Physiol. 2016 Jun

Laghmani K, Beck BB, Yang SS, Seaayfan E, Wenzel A, Reusch B, Vitzthum H, Priem D, Demaretz S, Bergmann K, Duin LK, Göbel H, Mache C, Thiele H, Bartram MP, Dombret C, Altmüller J, Nürnberg P, Benzing T, Levtchenko E, Seyberth HW, Klaus G, Yigit G, Lin SH, Timmer A, de Koning TJ, Scherjon SA, Schlingmann KP, Bertrand MJ, Rinschen MM, de Backer O, Konrad M, Kömhoff M.
Polyhydramnios, Transient Antenatal Bartter's Syndrome, and MAGED2 Mutations
N Engl J Med. 2016 May

Wenzel U, Turner JE, Krebs C, Kurts C, Harrison DG, Ehmke H.
Immune Mechanisms in Arterial Hypertension.
J Am Soc Nephrol. 2016 Mar;

Schaefer A, Schneeberger Y, Stenzig J, Biermann D, Jelinek M, Reichenspurner H, Eschenhagen T, Ehmke H, Schwoerer AP
A New Animal Model for Investigation of Mechanical Unloading in Hypertrophic and Failing Hearts: Combination of Transverse Aortic Constriction and Heterotopic Heart Transplantation.
PLoS One. 2016 Feb 3

Wollberg J, Bähring R.
Intra- and Intersubunit Dynamic Binding in Kv4.2 Channel Closed-State Inactivation.
Biophys J. 2016 Jan 5

K., Ravekes, T., Klinke, A., Friedrichs, K., Mollenhauer, M., Pekarova, M., Ambrozova, G., Martiskova, H., Kaur, J-J., Matthes, B., Schwoerer, A., Woodcock, S. R., Kubala, L., Freeman, B. A., Baldus, S. & Nitrated fatty acids suppress angiotensin II-mediated fibrotic remodelling and atrial fibrillation Rudolph, T. Rudolph, V. :
CARDIOVASC RES. 109, 1 , 01.01.2016S. 174-84

Publikationen ab 2005

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  • Wenzel UO, Bode M, Köhl J, Ehmke H.
    A pathogenic role of complement in arterial hypertension and hypertensive end organ damage.
    Am J Physiol Heart Circ Physiol. 2016 Dec 16

    Dyshlovoy SA, Otte K, Alsdorf WH, Hauschild J, Lange T, Venz S, Bauer CK, Bähring R, Amann K, Mandanchi R, Schumacher U, Schröder-Schwarz J, Makarieva TN, Guzii AG, Tabakmakher KM, Fedorov SN, Shubina LK, Kasheverov IE, Ehmke H, Steuber T, Stonik VA, Bokemeyer C, Honecker F, von Amsberg G.
    Marine compound rhizochalinin shows high in vitro and in vivo efficacy in castration resistant prostate cancer.
    Oncotarget. 2016 Oct 25;

    Mauerhöfer M, Bauer CK.
    Effects of Temperature on Heteromeric Kv11.1a/1b and Kv11.3 Channels.
    Biophys J. 2016 Aug 9 ;

    Weiss S, Rosendahl A, Czesla D, Meyer-Schwesinger C, Stahl RA, Ehmke H, Kurts C, Zipfel PF, Köhl J, Wenzel UO.
    The complement receptor C5aR1 contributes to renal damage but protects the heart in angiotensin II-induced hypertension.
    Am J Physiol Renal Physiol. 2016 Jun

    Laghmani K, Beck BB, Yang SS, Seaayfan E, Wenzel A, Reusch B, Vitzthum H, Priem D, Demaretz S, Bergmann K, Duin LK, Göbel H, Mache C, Thiele H, Bartram MP, Dombret C, Altmüller J, Nürnberg P, Benzing T, Levtchenko E, Seyberth HW, Klaus G, Yigit G, Lin SH, Timmer A, de Koning TJ, Scherjon SA, Schlingmann KP, Bertrand MJ, Rinschen MM, de Backer O, Konrad M, Kömhoff M.
    Polyhydramnios, Transient Antenatal Bartter's Syndrome, and MAGED2 Mutations
    N Engl J Med. 2016 May

    Wenzel U, Turner JE, Krebs C, Kurts C, Harrison DG, Ehmke H.
    Immune Mechanisms in Arterial Hypertension.
    J Am Soc Nephrol. 2016 Mar;

    Schaefer A, Schneeberger Y, Stenzig J, Biermann D, Jelinek M, Reichenspurner H, Eschenhagen T, Ehmke H, Schwoerer AP
    A New Animal Model for Investigation of Mechanical Unloading in Hypertrophic and Failing Hearts: Combination of Transverse Aortic Constriction and Heterotopic Heart Transplantation.
    PLoS One. 2016 Feb 3

    Wollberg J, Bähring R.
    Intra- and Intersubunit Dynamic Binding in Kv4.2 Channel Closed-State Inactivation.
    Biophys J. 2016 Jan 5

    K., Ravekes, T., Klinke, A., Friedrichs, K., Mollenhauer, M., Pekarova, M., Ambrozova, G., Martiskova, H., Kaur, J-J., Matthes, B., Schwoerer, A., Woodcock, S. R., Kubala, L., Freeman, B. A., Baldus, S. & Nitrated fatty acids suppress angiotensin II-mediated fibrotic remodelling and atrial fibrillation Rudolph, T. Rudolph, V. :
    CARDIOVASC RES. 109, 1 , 01.01.2016S. 174-84

  • Bähring R, Bauer CK.
    Easy Method to examine single nerve fiber excitability and conduction parameters using intact nonanesthetisized earthworms
    Adv Physiol Educ. 2014 Sep

    -

    Mesirca P, Alig J, Torrente AG, Müller JC, Marger L, Rollin A, Marquilly C, Vincent A, Dubel S, Bidaud I, Fernandez A, Seniuk A, Engeland B, Singh J, Miquerol L, Ehmke H, Eschenhagen T, Nargeot J, Wickman K, Isbrandt D, Mangoni ME.
    Cardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivation.
    Nat Commun. 2014 Aug

    -

    Lehners A, Lange S, Niemann G, Rosendahl A, Meyer-Schwesinger C, Oh J, Stahl R, Ehmke H, Benndorf R, Klinke A, Baldus S, Wenzel UO.
    Myeloperoxidase deficiency ameliorates progression of chronic kidney disease in mice.
    Am J Physiol Renal Physiol. 2014 Aug

    -

    Sachse G, Faulhaber J, Seniuk A, Ehmke H, Pongs O.
    Smooth muscle BK channel activity influences blood pressure independent of vascular tone in mice.
    J Physiol. 2014 Jun

    -

    Bergelt C, Lauke 2, Petersen-Ewert C, Jücker M, Bauer CK.
    Alcohol and nicotine -- Concept and evaluation of an interdisciplinary elective course with OSPE in preclinical medical education.
    GMS Z Med Ausbild. 2014 Feb

    -

    Heinze C, Seniuk A, Sokolov MV, Huebner AK, Klementowicz AE, Szijártó IA, Schleifenbaum J, Vitzthum H, Gollasch M, Ehmke H, Schroeder BC, Hübner CA.
    Disruption of vascular Ca2+-activated chloride currents lowers blood pressure.
    J Clin Invest. 2014 Feb

    -

    Vitzthum H, Seniuk A, Schulte LH, Müller ML, Hetz H, Ehmke H.
    Functional coupling of renal K+ and Na+ handling causes high blood pressure in Na+ replete mice.
    J Physiol. 2014

    -

    MarKrebs CF, Lange S, Niemann G, Rosendahl A, Lehners A, Meyer-Schwesinger C, Stahl RA, Benndorf RA, Velden J, Paust HJ, Panzer U, Ehmke H, Wenzel UO.
    Deficiency of the interleukin 17/23 axis accelerates renal injury in mice with deoxycorticosterone acetate+angiotensin ii-induced hypertension
    Hypertension. 2014 Mar

  • Rudolph V, Moenig C, Lubos E, Lubs D, Knap M, Schlüter M, Kuß O, Koschyk D, Schwoerer AP, Treede H, Schirmer J, Reichenspurner H, Ehmke H, Blankenberg S, Baldus S.
    Baseline systolic left ventricular function determines hemodynamic adaptation following percutaneous mitral valve repair.
    Int J Cardiol. 2013 Sep

    -

    Schwoerer AP, Neef S, Broichhausen I, Jacubeit J, Tiburcy M, Wagner M, Biermann D, Didié M, Vettel C, Maier LS, Zimmermann WH, Carrier L, Eschenhagen T, Volk T, El-Armouche A, Ehmke H.
    Enhanced Ca2+ influx through cardiac L-type Ca2+ channels maintains the systolic Ca 2+ transient in early cardiac atrophy induced by mechanical unloading.
    Pflugers Arch. 2013 Jul

    -

    Nebel M, Schwoerer AP, Warszta D, Siebrands CC, Limbrock AC, Swarbrick JM, Fliegert R, Weber K, Bruhn S, Hohenegger M, Geisler A, Herich L, Schlegel S, Carrier L, Eschenhagen T, Potter BV, Ehmke H, Guse AH.
    Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signaling and arrhythmias in the heart evoked by #-adrenergic stimulation.
    J Biol Chem. 2013 May

    -

    Didié M, Christalla P, Rubart M, Muppala V, Döker S, Unsöld B, El-Armouche A, Rau T, Eschenhagen T, Schwoerer AP, Ehmke H, Schumacher U, Fuchs S, Lange C, Becker A, Tao W, Scherschel JA, Soonpaa MH, Yang T, Lin Q, Zenke M, Han DW, Schöler HR, Rudolph C, Steinemann D, Schlegelberger B, Kattman S, Witty A, Keller G, Field LJ, Zimmermann WH.
    Parthenogenetic stem cells for tissue-engineered heart repair.
    J Clin Invest. 2013 Mar

  • Witzel K, Fischer P, Bähring R.
    Hippocampal A-type current and Kv4.2 channel modulation by the sulfonylurea compound NS5806.
    Neuropharmacology. 2012 Dec


    Bilet A, Bauer CK.
    Effects of the Small Molecule HERG Activator NS1643 on Kv11.3 Channels.
    PLoS One. 2012 Nov


    Biermann D, Heilmann A, Didié M, Schlossarek S, Wahab A, Grimm M, Römer M, Reichenspurner H, Sultan KR, Steenpass A, Ergün S, Donzelli S, Carrier L, Ehmke H, Zimmermann WH, Hein L, Böger RH, Benndorf RA.
    Impact of AT2 receptor deficiency on postnatal cardiovascular development.
    PLoS One. 2012 Okt


    Sydow K, Schmitz C, von Leitner EC, von Leitner R, Klinke A, Atzler D, Krebs C, Wieboldt H, Ehmke H, Schwedhelm E, Meinertz T, Blankenberg S, Böger RH, Magnus T, Baldus S, Wenzel U.
    Dimethylarginine dimethylaminohydrolase1 is an organ-specific mediator of end organ damage in a murine model of hypertension.
    PLoS One. 2012 Okt


    Vierk R, Glassmeier G, Zhou L, Brandt N, Fester L, Dudzinski D, Wilkars W, Bender RA, Lewerenz M, Gloger S, Graser L, Schwarz J, Rune GM
    Aromatase inhibition abolishes LTP generation in female but not in male mice
    J Neurosci. 2012 Jun


    Bähring R, Barghaan J, Westermeier R, Wollberg J.
    Voltage sensor inactivation in potassium channels.
    Front Pharmacol. 2013 Mai


    Windhorst S, Minge D, Bähring R, Hüser S, Schob C, Blechner C, Lin HY, Mayr GW, Kindler S.
    Inositol-1,4,5-trisphosphate 3-kinase A regulates dendritic morphology and shapes synaptic Ca2+ transients.
    Cell Signal. 2012 Mar


    Faulhaber J, Ehmke H, Koenen W, Weiss B, Goerdt S, Schneider SW.
    Compartment syndrome of the lower leg after punch biopsy.
    Dermatol Surg. 2012 Feb;Glassmeier G, Hempel K, Wulfsen I, Bauer CK, Schumacher U, Schwarz JR
    Inhibition of HERG1 K(+) channel protein expression decreases cell proliferation of human small cell lung cancer cells
    Pflugers Arch. 2012 Feb


    Ehmke H.
    The sigma-1 receptor: a molecular chaperone for the heart and the soul?
    Cardiovasc Res. 2012 Jan

  • Lange A, Gustke H, Glassmeier G, Heine M, Zangemeister-Wittke U, Schwarz JR, Schumacher U, Lange T.
    Neuronal differentiation by indomethacin and IBMX inhibits proliferation of small cell lung cancer cells in vitro.
    Lung Cancer. 2011 Nov


    Cordeiro S, Guseva D, Wulfsen I, Bauer CK.
    Expression pattern of Kv11 (Ether à-go-go-related gene; erg) K+ channels in the mouse retina.
    PLoS One. 2011


    Windhorst S, Minge D, Bähring R, Hüser S, Schob C, Blechner C, Lin HY, Mayr GW, Kindler S.
    Inositol-1,4,5-trisphosphate 3-kinase A regulates dendritic morphology and shapes synaptic Ca(2+) transients
    Cell Signal. 2011 Nov.


    Schuster AM, Glassmeier G, Bauer CK.
    Strong Activation of ether-a-go-go-Related Gene 1 K+ Channel Isoforms by NS1643 in Human Embryonic Kidney 293 and Chinese Hamster Ovary Cells
    Mol Pharmacol. 2011 NovGröger N, Vitzthum H, Fröhlich H, Krüger M, Ehmke H, Braun T, Boettger T.
    Targeted mutation of SLC4A5 induces arterial hypertension and renal metabolic acidosis.
    Hum Mol Genet. 2011 Nov


    von Leitner EC, Klinke A, Atzler D, Slocum JL, Lund N, Kielstein JT, Maas R, Schmidt-Haupt R, Pekarova M, Hellwinkel O, Tsikas D, D'Alecy LG, Lau D, Willems S, Kubala L, Ehmke H, Meinertz T, Blankenberg S, Schwedhelm E, Gadegbeku CA, Böger RH, Baldus S, Sydow K.
    Pathogenic Cycle Between the Endogenous Nitric Oxide Synthase Inhibitor Asymmetrical Dimethylarginine and the Leukocyte-Derived Hemoprotein Myeloperoxidase.
    Circulation. 2011 Nov


    Schwoerer AP, Zenouzi R, Ehmke H, Friederich P.
    Bupivacaine Destabilizes Action Potential Duration in Cellular and Computational Models of Long QT Syndrome 1.
    Anesth Analg. 2011 OctMinge D, Bähring R.
    Acute Alterations of Somatodendritic Action Potential Dynamics in Hippocampal CA1 Pyramidal Cells after Kainate-Induced Status Epilepticus in Mice.
    PLoS One. 2011


    Rudolph TK, Wipper S, Reiter B, Rudolph V, Coym A, Detter C, Lau D, Klinke A, Friedrichs K, Rau T, Pekarova M, Russ D, Knöll K, Kolk M, Schroeder B, Wegscheider K, Andresen H, Schwedhelm E, Boeger R, Ehmke H, Baldus S.
    Myeloperoxidase deficiency preserves vasomotor function in humans.
    Eur Heart J. 2011 Jun 30.


    Heisler FF, Loebrich S, Pechmann Y, Maier N, Zivkovic AR, Tokito M, Hausrat TJ, Schweizer M, Bähring R, Holzbaur EL, Schmitz D, Kneussel M.
    Muskelin regulates actin filament- and microtubule-based GABA(A) receptor transport in neurons.
    Neuron, 2011 Apr


    Bott-Flügel L, Bernshausen A, Schneider H, Luppa P, Zimmermann K, Albrecht-Küpper B, Kast R, Laugwitz KL, Ehmke H, Knorr A, Seyfarth M.
    Selective attenuation of norepinephrine release and stress-induced heart rate increase by partial adenosine A1 agonism.
    PLoS One. 2011 Mar


    Marger L, Mesirca P, Alig J, Torrente A, Dubel S, Engeland B, Kanani S, Fontanaud P, Striessnig J, Shin HS, Isbrandt D, Ehmke H, Nargeot J, Mangoni ME.
    Functional roles of Ca(v)1.3, Ca(v)3.1 and HCN channels in automaticity of mouse atrioventricular cells: insights into the atrioventricular pacemaker mechanism.
    Channels (Austin). 2011 May-Jun


    Marger L, Mesirca P, Alig J, Torrente A, Dubel S, Engeland B, Kanani S, Fontanaud P, Striessnig J, Shin HS, Isbrandt D, Ehmke H, Nargeot J, Mangoni ME.
    Pacemaker activity and ionic currents in mouse atrioventricular node cells.
    Channels (Austin). 2011 May-JunBähring R, Covarrubias M.
    Mechanisms of closed-state inactivation in voltage-gated ion channels.
    J Physiol. 2011 Feb


    Klinke A, Nussbaum C, Kubala L, Friedrichs K, Rudolph TK, Rudolph V, Paust HJ, Schröder C, Benten D, Lau D, Szocs K, Furtmüller PG, Heeringa P, Sydow K, Duchstein HJ, Ehmke H, Schumacher U, Meinertz T, Sperandio M, Baldus S.
    Myeloperoxidase attracts neutrophils by physical forces
    Blood. 2011 Jan

  • El-Armouche A, Schwoerer AP, Neuber C, Emons J, Biermann D, Christalla T, Grundhoff A, Eschenhagen T, Zimmermann WH, Ehmke H.
    Common microRNA signatures in cardiac hypertrophic and atrophic remodeling induced by changes in hemodynamic load.
    PLoS One. 2010 Dec


    Riede F, Koenen W, Goerdt S, Ehmke H, Faulhaber J.
    Medicinal leeches for the treatment of venous congestion and hematoma after plastic reconstructive surgery.
    J Dtsch Dermatol Ges. 2010 Nov


    Schwoerer AP, Kebernik J, Ehmke H, Friederich P.
    The subtype-specific effects of droperidol on action potential duration in cellular and computational models of long QT syndrome.
    Anesth Analg. 2010 Sep


    Kleene R, Cassens C, Bähring R, Theis T, Xiao MF, Dityatev A, Schafer-Nielsen C, Döring F, Wischmeyer E, Schachner M.
    Functional consequences of the interactions among the neural cell adhesion molecule NCAM, the receptor tyrosine kinase TrkB, and the inwardly rectifying K+ channel KIR3.3.
    J Biol Chem. 2010


    Mewe M, Mauerhöfer M, Wulfsen I, Szlachta K, Zhou XB, Schwarz JR, Bauer CK.
    Modulation of cardiac ERG1 K(+) channels by cGMP signaling
    J Mol Cell Cardiol. 2010 Jul


    Rudolph V, Andrié RP, Rudolph TK, Friedrichs K, Klinke A, Hirsch-Hoffmann B, Schwoerer AP, Lau D, Fu X, Klingel K, Sydow K, Didié M, Seniuk A, von Leitner EC, Szoecs K, Schrickel JW, Treede H, Wenzel U, Lewalter T, Nickenig G, Zimmermann WH, Meinertz T, Böger RH, Reichenspurner H, Freeman BA, Eschenhagen T, Ehmke H, Hazen SL, Willems S, Baldus S.
    Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation.
    Nat Med. 2010 Apr;16(4):470-4.


    Wagner M, Rudakova E, Schütz V, Frank M, Ehmke H, Volk T.
    Larger transient outward K(+) current and shorter action potential duration in Galpha(11) mutant mice.
    Pflugers Arch. 2010 Mar;


    Hirdes W, Dinu C, Bauer CK, Boehm U, Schwarz JR.
    Gonadotropin-Releasing Hormone Inhibits Ether-a-Go-Go-Related Gene K+ Currents in Mouse Gonadotropes.
    Endocrinology. 2010 Jan 12.


    Tozakidou M, Goltz D, Hagenström T, Budack MK, Vitzthum H, Szlachta K, Bähring R, Ehmke H.
    Molecular and functional remodeling of I(to) by angiotensin II in the mouse left ventricle.
    J Mol Cell Cardiol. 2009 Sep

  • Hirdes W, Napp N, Wulfsen I, Schweizer M, Schwarz JR, Bauer CK.
    Erg K+ currents modulate excitability in mouse mitral/tufted neurons.
    Pflugers Arch. 2009 Nov;459(1):55-70. Epub 2009 Aug 18.PMID: 19688350


    Benndorf RA, Krebs C, Hirsch-Hoffmann B, Schwedhelm E, Cieslar G, Schmidt-Haupt R, Steinmetz OM, Meyer-Schwesinger C, Thaiss F, Haddad M, Fehr S, Heilmann A, Helmchen U, Hein L, Ehmke H, Stahl RA, Böger RH, Wenzel UO.
    Angiotensin II type 2 receptor deficiency aggravates renal injury and reduces survival in chronic kidney disease in mice.
    Kidney Int 2009; 75(10):1039-49.


    Alig J, Marger L, Mesirca P, Ehmke H, Mangoni ME, Isbrandt D.
    Control of heart rate by cAMP sensitivity of HCN channels.
    Proc Natl Acad Sci USA 2009;106(29):12189-94.


    Adriouch, S., Scheuplein, F., Bähring, R., Seman, M., Boyer, O., Koch-Nolte, F., and Haag, F., Characterisation of the R276A gain-of-function mutation in the ectodomain of murine P2X7.
    Purinergic Signal. 5: 151-161 (2009).


    Wagner M, Rudakova E, Schütz V, Frank M, Ehmke H, Volk T.
    Larger transient outward K(+) current and shorter action potential duration in Galpha(11) mutant mice.
    Pflugers Arch. 2009 (in print)


    Barghaan J, Bähring R.
    Dynamic coupling of voltage sensor and gate involved in closed-state inactivation of kv4.2 channels.
    J Gen Physiol. 2009 Feb;133(2):205-24.


    Schmechel A, Grimm M, El-Armouche A, Höppner G, Schwoerer AP, Ehmke H, Eschenhagen T.
    Treatment with atorvastatin partially protects the rat heart from harmful catecholamine effects.
    Cardiovasc Res. 2009 Apr 1


    Liew CW, Vockel M, Glassmeier G, Brandner JM, Fernandez-Ballester GJ, Schwarz JR, Schulz S, Buck F, Serrano L, Richter D, Kreienkamp HJ.
    Interaction of the human somatostatin receptor 3 with the multiple PDZ domain protein MUPP1 enables somatostatin to control permeability of epithelial tight junctions.
    FEBS Lett. 2009 Jan 5;583(1):49-54. Epub 2008 Dec 9.PMID: 19071123

  • Schwoerer AP, Neuber C, Schmechel A, Melnychenko I, Mearini G, Boknik P, Kirchhefer U, Schmitz W, Ehmke H, Eschenhagen T, El-Armouche A.
    Mechanical unloading of the rat heart involves marked changes in the protein kinase-phosphatase balance.J Mol Cell Cardiol. 2008 Dec


    Schwoerer AP, Melnychenko I, Goltz D, Hedinger N, Broichhausen I, El-Armouche A, Eschenhagen T, Volk T, Ehmke H.
    Unloaded rat hearts in vivo express a hypertrophic phenotype of cardiac repolarization.
    J Mol Cell Cardiol. 2008 Nov


    Wen S, Schwarz JR, Niculescu D, Dinu C, Bauer CK, Hirdes W, Boehm U.
    Functional characterization of genetically labeled gonadotropes.
    Endocrinology. 2008 Jun


    Mewe M, Wulfsen I, Schuster AM, Middendorff R, Glassmeier G, Schwarz JR, Bauer CK.
    Erg K+ channels modulate contractile activity in the bovine epididymal duct.
    Am J Physiol Regul Integr Comp Physiol. 2008 Mar


    Barghaan J, Tozakidou M, Ehmke H, Bähring R.
    Role of N-terminal domain and accessory subunits in controlling deactivation-inactivation coupling of Kv4.2 channels.
    Biophys J. 2008 Feb

  • Kast R, Schirok H, Figueroa-Pérez S, Mittendorf J, Gnoth MJ, Apeler H, Lenz J, Franz JK, Knorr A, Hütter J, Lobell M, Zimmermann K, Münter K, Augstein KH, Ehmke H, Stasch JP.
    Cardiovascular effects of a novel potent and highly selective azaindole-based inhibitor of Rho-kinase.
    Br J Pharmacol. 2007 Dec;152(7):1070-80. Epub 2007 Oct 15.


    Mewe M, Wulfsen I, Middendorff R, Bauer CK.
    Differential modulation of bovine epididymal activity by oxytocin and noradrenaline.
    Reproduction. 2007 Sep;134(3):493-501.

    Wagner M, Goltz D, Stucke C, Schwoerer AP, Ehmke H, Volk T.
    Modulation of the transient outward K+ current by inhibition of endothelin-A receptors in normal and hypertrophied rat hearts.
    Pflugers Arch. 2007 Jul;454(4):595-604. Epub 2007 Feb 27.

    Schultz JH, Volk T, Bassalaý P, Hennings JC, Hübner CA, Ehmke H.
    Molecular and functional characterization of Kv4.2 and KChIP2 expressed in the porcine left ventricle.
    Pflugers Arch. 2007 May;454(2):195-207. Epub 2007 Jan 23.

    Schwoerer AP, Blütner C, Brandt S, Binder S, Siebrands CC, Ehmke H, Friederich P.
    Molecular interaction of droperidol with human ether-a-go-go-related gene channels: prolongation of action potential duration without inducing early afterdepolarization.
    Anesthesiology. 2007 May;106(5):967-76.

    Suleiman H, Heudobler D, Raschta AS, Zhao Y, Zhao Q, Hertting I, Vitzthum H, Moeller MJ, Holzman LB, Rachel R, Johnson R, Westphal H, Rascle A, Witzgall R.
    The podocyte-specific inactivation of Lmx1b, Ldb1 and E2a yields new insight into a transcriptional network in podocytes.
    Dev Biol. 2007 Apr 15;304(2):701-12. Epub 2007 Jan 18.


    Goltz D, Schultz JH, Stucke C, Wagner M, Bassalaý P, Schwoerer AP, Ehmke H, Volk T.
    Diminished Kv4.2/3 but not KChIP2 levels reduce the cardiac transient outward K+ current in spontaneously hypertensive rats.
    Cardiovasc Res. 2007 Apr 1;74(1):85-95. Epub 2007 Jan 8.

    Fliegert R, Glassmeier G, Schmid F, Cornils K, Genisyuerek S, Harneit A, Schwarz JR, Guse AH.
    Modulation of Ca2+ entry and plasma membrane potential by human TRPM4b.
    FEBS J. 2007 Feb

  • Konrad M, Schaller A, Seelow D, Pandey AV, Waldegger S, Lesslauer A, Vitzthum H, Suzuki Y, Luk JM, Becker C, Schlingmann KP, Schmid M, Rodriguez-Soriano J, Ariceta G, Cano F, Enriquez R, Juppner H, Bakkaloglu SA, Hediger MA, Gallati S, Neuhauss SC, Nurnberg P, Weber S.
    Mutations in the tight-junction gene claudin 19 (CLDN19) are associated with renal magnesium wasting, renal failure, and severe ocular involvement.
    Am J Hum Genet. 2006 Nov;79(5):949-57


    Mewe M, Bauer CK, Schwarz JR, Middendorff R.
    Mechanisms regulating spontaneous contractions in the bovine epididymal duct.
    Biol Reprod. 2006 Oct;75(4):651-9.


    Choe CU, Schulze-Bahr E, Neu A, Xu J, Zhu ZI, Sauter K, Bähring R, Priori S, Guicheney P, Mönnig G, Neapolitano C, Heidemann J, Clancy CE, Pongs O, Isbrandt D.
    C-terminal HERG (LQT2) mutations disrupt IKr channel regulation through 14-3-3epsilon.
    Hum Mol Genet. 2006 Oct 1;15(19):2888-902


    Templin C, Kotlarz D, Marquart F, Faulhaber J, Brendecke V, Schaefer A, Tsikas D, Bonda T, Hilfiker-Kleiner D, Ohl L, Naim HY, Foerster R, Drexler H, Limbourg FP.
    Transcoronary delivery of bone marrow cells to the infarcted murine myocardium: feasibility, cellular kinetics, and improvement in cardiac function.
    Basic Res Cardiol. 2006 Jul;101(4):301-10


    OELZE M, WARNHOLTZ A, FAULHABER J, WENZEL P, KLESCHYOV AL, COLDEWEY M, HINK U, PONGS O, FLEMING I, WASSMANN S, MEINERTZ T, EHMKE H, DAIBER A, MUNZEL T.
    NADPH Oxidase Accounts for Enhanced Superoxide Production and Impaired Endothelium-Dependent Smooth Muscle Relaxation in BK{beta}1-/- Mice.
    Arterioscler Thromb
    Vasc Biol. 2006 Jun


    Schwarz JR, Glassmeier G, Cooper EC, Kao TC, Nodera H, Tabuena D, Kaji R, Bostock H.
    KCNQ channels mediate IKs, a slow K+ current regulating excitability in the rat node of Ranvier.
    J Physiol. 2006 May 15;573(Pt 1):17-34


    ZIMMERMANN WH, MELNYCHENKO I, WASMEIER G, DIDIE M, NAITO H, NIXDORF U, HESS A, BUDINSKY L, BRUNE K, MICHAELIS B, DHEIN S,
    SCHWOERER A, EHMKE H, ESCHENHAGEN T
    Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts.
    Nat Med. 2006 Apr;12(4):452-8.


    Mewe M, Bauer CK, Müller D, Middendorff R.
    Regulation of spontaneous contractile activity in the bovine epididymal duct by cyclic guanosine 5'-monophosphate-dependent pathways.
    Endocrinology. 2006 Apr;147(4):2051-62.


    Reinhold SW, Vitzthum H, Filbeck T, Wolf K, Lattas C, Riegger GA, Kurtz A, Krämer BK.Gene expression of 5-, 12-, and 15-lipoxygenases and leukotriene receptors along the rat nephron.
    Am J Physiol Renal Physiol. 2006 Apr;290(4):F864-72.Loebrich S, Bähring R, Katsuno T, Tsukita S, Kneussel M.
    Activated radixin is essential for GABAA receptor alpha5 subunit anchoring at the actin cytoskeleton.
    EMBO J. 2006 Mar 8;25(5):987-99.


    Rezgaoui M, Süsens U, Ignatov A, Gelderblom M, Glassmeier G, Franke I, Urny J, Imai Y, Takahashi R, Schaller HC.
    The neuropeptide head activator is a high-affinity ligand for the orphan G-protein-coupled receptor GPR37.
    J Cell Sci. 2006 Feb 1;119(Pt 3):542-9.


    Gasser A, Glassmeier G, Fliegert R, Langhorst MF, Meinke S, Hein D, Krüger S, Weber K, Heiner I, Oppenheimer N, Schwarz JR, Guse AH.
    Activation of T cell calcium influx by the second messenger ADP-ribose.
    J Biol Chem. 2006 Feb 3;281(5):2489-96. kjk


    Kirchberger NM, Wulfsen I, Schwarz JR, Bauer CK.
    Effects of TRH on heteromeric rat erg1a/1b K+ channels are dominated by the rerg1b subunit.
    J Physiol. 2006 Feb 15;571(Pt 1):27-42.


    RUST MB, FAULHABER J, BUDACK MK, PFEFFER C, MARITZEN T, DIDIE M, BECK FX, BOETGER T, SCHUBERT R, EHMKE H, JENTSCH TJ, HUBNER CA.
    Neurogenic Mechanisms Contribute to Hypertension in Mice With Disruption of the K-Cl Cotransporter KCC3.
    Circ Res. 2006 Jan 19


    AMANN K, FAULHABER J, CAMPEAN V, BALJEW V, DONO R, MALL G, EHMKE H.
    Impaired myocardial capillarogenesis and increased adaptive capillary growth in FGF2-deficient mice.
    Lab Invest. 2006 Jan

  • Callsen B, Isbrandt D, Sauter K, Hartmann LS, Pongs O, Bähring R.
    Contribution of N- and C-terminal Kv4.2 channel domains to KChIP interaction [corrected]
    J Physiol. 2005 Oct 15;568(Pt 2):397-412.EHMKE H.
    Neurogenic mechanisms and salt sensitivity.
    Hypertension. 2005 Dec;46(6):1259-60.


    SCHULTZ JH, JANZEN C, VOLK T, EHMKE H.
    Kv4.2 and KChIP2 transcription in individual cardiomyocytes from the rat left ventricular free wall.
    J Mol Cell Cardiol. 2005 Aug;39(2):269-75


    Sturm P, Wimmers S, Schwarz JR, Bauer CK.
    Extracellular potassium effects are conserved within the rat erg K+ channel family.
    J Physiol. 2005 Apr 15;564(Pt 2):329-45.


    Hirdes W, Schweizer M, Schuricht KS, Guddat SS, Wulfsen I, Bauer CK, Schwarz JR.
    Fast erg K+ currents in rat embryonic serotonergic neurones.
    J Physiol. 2005 Apr 1;564(Pt 1):33-49.


    VOLK T, NOBLE PJ, WAGNER M, NOBLE D, EHMKE H.
    Ascending aortic stenosis selectively increases action potential-induced Ca2+ influx in epicardial myocytes of the rat left ventricle.
    Exp Physiol. 2005 Jan;90(1)