Publikationen der Sektion Pädiatrische Stammzelltransplantation und Immunologie

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2018

CD34+ selected stem cell boosts can improve poor graft function after paediatric allogeneic stem cell transplantation
Mainardi C, Ebinger M, Enkel S, Feuchtinger T, Teltschik H, Eyrich M, Schumm M, Rabsteyn A, Schlegel P, Seitz C, Schwarze C, Müller I, Greil J, Bader P, Schlegel P, Martin D, Holzer U, Döring M, Handgretinger R, Lang P
BRIT J HAEMATOL. 2018;180(1):90-99.

2017

Enzymatic characterization of novel arylsulfatase A variants using human arylsulfatase A-deficient immortalized mesenchymal stromal cells
Böhringer J, Santer R, Schumacher N, Gieseke F, Cornils K, Pechan M, Kustermann-Kuhn B, Handgretinger R, Schöls L, Harzer K, Krägeloh-Mann I, Müller I
HUM MUTAT. 2017;38(11):1511-1520.

Efficacy, safety and feasibility of antifungal prophylaxis with posaconazole tablet in paediatric patients after haematopoietic stem cell transplantation
Döring M, Cabanillas Stanchi K, Queudeville M, Feucht J, Blaeschke F, Schlegel P, Feuchtinger T, Lang P, Müller I, Handgretinger R, Heinz W
J CANCER RES CLIN. 2017;143(7):1281-1292.

Hematopoietic stem cell transplantation rescues the hematological, immunological and vascular phenotype in DADA2
Hashem H, Kumar A, Müller I, Babor F, Bredius R, Dalal J, Hsu A, Holland S, Hickstein D, Jolles S, Krance R, Sasa G, Taskinen M, Koskenvuo M, Saarela J, van Montfrans J, Wilson K, Bosch B, Moens L, Hershfield M, Meyts I
BLOOD. 2017;130(24):2682-2688.

Bone Marrow-Derived Stem Cells Migrate into Intra-epidermal Skin Defects of a Desmoglein-3 knockout Mouse Model but Preserve their Mesodermal Differentiation
Hünefeld C, Mezger M, Müller-Hermelink E, Schaller M, Müller I, Amagai M, Handgretinger R, Röcken M
J INVEST DERMATOL. 2017 [Epub ahead of print].

Mutations in EXTL3 Cause Neuro-immuno-skeletal Dysplasia Syndrome
Oud M, Tuijnenburg P, Hempel M, van Vlies N, Ren Z, Ferdinandusse S, Jansen M, Santer R, Johannsen J, Bacchelli C, Alders M, Li R, Davies R, Dupuis L, Cale C, Wanders R, Pals S, Ocaka L, James C, Müller I, Lehmberg K, Strom T, Engels H, Williams H, Beales P, Roepman R, Dias P, Brunner H, Cobben J, Hall C, Hartley T, Le Quesne Stabej P, Mendoza-Londono R, Davies E, de Sousa S, Lessel D, Arts H, Kuijpers T
AM J HUM GENET. 2017;100(2):281-296.

Lineage switch under blinatumomab treatment of relapsed common acute lymphoblastic leukemia without MLL rearrangement
Zoghbi A, Zur Stadt U, Winkler B, Müller I, Escherich G
PEDIATR BLOOD CANCER. 2017;64(11):11.

2016

Feasibility of CD3/CD19 depletion of a bone marrow graft
Bonig H, Müller I
CYTOTHERAPY. 2016;18(10):1345-7.

Treatment and outcome of Ganglioneuroma and Ganglioneuroblastoma intermixed
Decarolis B, Simon T, Krug B, Leuschner I, Vokuhl C, Kaatsch P, von Schweinitz D, Klingebiel T, Müller I, Schweigerer L, Berthold F, Hero B
BMC CANCER. 2016;16:542.

Ferritin as an early marker of graft rejection after allogeneic hematopoietic stem cell transplantation in pediatric patients
Döring M, Cabanillas Stanchi K, Feucht J, Queudeville M, Teltschik H, Lang P, Feuchtinger T, Handgretinger R, Müller I
ANN HEMATOL. 2016;95(2):311-23.

Long-term Outcome of Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Juvenile Metachromatic Leukodystrophy Compared With Nontransplanted Control Patients
Groeschel S, Kühl J, Bley A, Kehrer C, Weschke B, Döring M, Böhringer J, Schrum J, Santer R, Kohlschütter A, Krägeloh-Mann I, Müller I
JAMA NEUROL. 2016;73(9):1133-40.

The minimum required level of donor chimerism in hereditary hemophagocytic lymphohistiocytosis
Hartz B, Marsh R, Rao K, Henter J, Jordan M, Filipovich L, Bader P, Beier R, Burkhardt B, Meisel R, Schulz A, Winkler B, Albert M, Greil J, Karasu G, Woessmann W, Corbaciologlu S, Gruhn B, Holter W, Kühl J, Lang P, Seidel M, Veys P, Löfstedt A, Ammann S, Ehl S, Janka G, Müller I, Lehmberg K
BLOOD. 2016;127(25):3281-90.

Treosulfan based conditioning for allogeneic HSCT in children with chronic granulomatous disease: a multicentre experience
Morillo-Gutierrez B, Beier R, Rao K, Burroughs L, Schulz A, Ewins A, Gibson B, Sedlacek P, Krol L, Strahm B, Zaidman I, Kalwak K, Talano J, Woolfrey A, Fraser C, Meyts I, Müller I, Wachowiak J, Bernardo M, Veys P, Sykora K, Gennery A, Slatter M
BLOOD. 2016;128(3):440-8.

Fracture Healing Is Delayed in Immunodeficient NOD/scid‑IL2Rγcnull Mice
Rapp A, Bindl R, Recknagel S, Erbacher A, Müller I, Schrezenmeier H, Ehrnthaller C, Gebhard F, Ignatius A
PLOS ONE. 2016;11(2):e0147465.

Musculoskeletal manifestations in mucopolysaccharidosis type I (Hurler syndrome) following hematopoietic stem cell transplantation
Schmidt M, Breyer S, Löbel U, Yarar S, Stücker R, Ullrich K, Müller I, Muschol N
ORPHANET J RARE DIS. 2016;11(1):93.

2015

Monitoring of Minimal Residual Disease After Allogeneic Stem-Cell Transplantation in Relapsed Childhood Acute Lymphoblastic Leukemia Allows for the Identification of Impending Relapse: Results of the ALL-BFM-SCT 2003 Trial
Bader P, Kreyenberg H, von Stackelberg A, Eckert C, Salzmann-Manrique E, Meisel R, Poetschger U, Stachel D, Schrappe M, Alten J, Schrauder A, Schulz A, Lang P, Müller I, Albert M, Willasch A, Klingebiel T, Peters C
J CLIN ONCOL. 2015;33(11):1275 - 84.

Consensus of German transplant centers on hematopoietic stem cell transplantation in Fanconi anemia
Chao M, Ebell W, Bader P, Beier R, Burkhardt B, Feuchtinger T, Handgretinger R, Hanenberg H, Koehl U, Kratz C, Kremens B, Lang P, Meisel R, Müller I, Roessig C, Sauer M, Schlegel P, Schulz A, Strahm B, Thol F, Sykora K
KLIN PADIATR. 2015;227(3):157-65.

Cytokine serum levels during post-transplant adverse events in 61 pediatric patients after hematopoietic stem cell transplantation
Döring M, Cabanillas Stanchi K, Mezger M, Erbacher A, Feucht J, Pfeiffer M, Lang P, Handgretinger R, Müller I
BMC CANCER. 2015;15:Art. 607.

Antifungal prophylaxis with posaconazole vs. fluconazole or itraconazole in pediatric patients with neutropenia
Döring M, Eikemeier M, Cabanillas Stanchi K, Hartmann U, Ebinger M, Schwarze C, Schulz A, Handgretinger R, Müller I
EUR J CLIN MICROBIOL. 2015;34(6):1189-1200.

Multipotent Mesenchymal Stromal Cells: Possible Culprits in Solid Tumors?
Johann P, Müller I
Stem Cells Int. 2015;2015:914632.

Risk of Rotavirus Vaccination for Children with SCID
Klinkenberg D, Blohm M, Hoehne M, Mas Marques A, Malecki M, Schildgen V, Schneppenheim R, Müller I, Schildgen O, Kobbe R
PEDIATR INFECT DIS J. 2015;34(1):114-5.

Donor choice in haploidentical stem cell transplantation: fetal microchimerism is associated with better outcome in pediatric leukemia patients
Kruchen A, Stahl T, Gieseke F, Binder T, Özcan Z, Meisel R, Kreyenberg H, Bader P, Gruhn B, Greil J, Pfeiffer M, Döring M, Handgretinger R, Fehse B, Müller I
BONE MARROW TRANSPL. 2015;50(10):1367-1370.

Malignancy-associated haemophagocytic lymphohistiocytosis in children and adolescents
Lehmberg K, Sprekels B, Nichols K, Woessmann W, Müller I, Suttorp M, Bernig T, Beutel K, Bode S, Kentouche K, Kolb R, Längler A, Minkov M, Schilling F, Schmid I, Vieth S, Ehl S, Zur Stadt U, Janka G
BRIT J HAEMATOL. 2015;170(4):539-49.

Klinische Praxis - Spenderfindung und Stammzelltransplantation
Müller I
2015. Rettende Geschwister. Schües C, Rehmann-Sutter C (Hrsg.). 2015. Aufl. Münster: Mentis, 25 - 32.

Systemic mesenchymal stem cell administration enhances bone formation in fracture repair but not load-induced bone formation
Rapp A, Bindl R, Heilmann A, Erbacher A, Müller I, Brenner R, Ignatius A
EUR CELLS MATER. 2015;29:22-34.

Standardization of Good Manufacturing Practice-compliant production of bone marrow-derived human mesenchymal stromal cells for immunotherapeutic applications
Wuchter P, Bieback K, Schrezenmeier H, Bornhäuser M, Müller L, Bönig H, Wagner W, Meisel R, Pavel P, Tonn T, Lang P, Müller I, Renner M, Malcherek G, Saffrich R, Buss E, Horn P, Rojewski M, Schmitt A, Ho A, Sanzenbacher R, Schmitt M
CYTOTHERAPY. 2015;17(2):128-139.

2014

Comparison of itraconazole, voriconazole, and posaconazole as oral antifungal prophylaxis in pediatric patients following allogeneic hematopoietic stem cell transplantation
Döring M, Blume O, Haufe S, Hartmann U, Kimmig A, Schwarze C, Lang P, Handgretinger R, Müller I
EUR J CLIN MICROBIOL. 2014;33(4):629-38.

Transplantation of CD3/CD19 depleted allografts from haploidentical family donors in paediatric leukaemia
Lang P, Teltschik H, Feuchtinger T, Müller I, Pfeiffer M, Schumm M, Ebinger M, Schwarze C, Gruhn B, Schrauder A, Albert M, Greil J, Urban C, Handgretinger R
BRIT J HAEMATOL. 2014;165(5):688-98.

Treosulfan-based conditioning regimen for children and adolescents with hemophagocytic lymphohistiocytosis
Lehmberg K, Albert M, Beier R, Beutel K, Gruhn B, Kröger N, Meisel R, Schulz A, Stachel D, Woessmann W, Janka G, Müller I
HAEMATOLOGICA. 2014;99(1):180-4.

Signal-peptide-peptidase-like 2a is required for CD74 intramembrane proteolysis in human B cells
Schneppenheim J, Hüttl S, Kruchen A, Fluhrer R, Müller I, Saftig P, Schneppenheim R, Martin C, Schröder B
BIOCHEM BIOPH RES CO. 2014;451(1):48-53.

2013

Allo-SCT using BU, CY and melphalan for children with AML in second CR
Beier R, Albert M, Bader P, Borkhardt A, Creutzig U, Eyrich M, Ehlert K, Gruhn B, Greil J, Handgretinger R, Holter W, Klingebiel T, Kremens B, Lang P, Mauz-Körholz C, Meisel R, Müller I, Peters C, Reinhardt D, Sedlacek P, Schulz A, Schuster F, Schrauder A, Strahm B, Sykora K, Wössmann W, Zimmermann M, Sauer M
BONE MARROW TRANSPL. 2013;48(5):651-6.

Long-term follow-up of children conditioned with Treosulfan: German and Austrian experience
Beier R, Schulz A, Hönig M, Eyrich M, Schlegel P, Holter W, Stachel K, Ehlert K, Greil J, Nürnberger W, Wössmann W, Bader P, Urban C, Müller I, Suttorp M, Sauer M, Gruhn B, Meisel R, Zimmermann M, Sykora K
BONE MARROW TRANSPL. 2013;48(4):491-501.

Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation
Gieseke F, Kruchen A, Tzaribachev N, Bentzien F, Dominici M, Müller I
EUR J IMMUNOL. 2013;43(10):2741-9.

Activated human hepatic stellate cells induce myeloid derived suppressor cells from peripheral blood monocytes in a CD44-dependent fashion
Höchst B, Schildberg F, Sauerborn P, Gäbel Y, Gevensleben H, Goltz D, Heukamp L, Türler A, Ballmaier M, Gieseke F, Müller I, Kalff J, Kurts C, Knolle P, Diehl L
J HEPATOL. 2013;59(3):528-35.

One goal, different strategies--molecular and cellular approaches for the treatment of inherited skin fragility disorders
Hünefeld C, Mezger M, Kern J, Nyström A, Bruckner-Tuderman L, Müller I, Handgretinger R, Röcken M
EXP DERMATOL. 2013;22(3):162-7.

Juvenile metachromatic leukodystrophy 10 years post transplant compared with a non-transplanted cohort
Krägeloh-Mann I, Groeschel S, Kehrer C, Opherk K, Nägele T, Handgretinger R, Müller I
BONE MARROW TRANSPL. 2013;48(3):369-75.

Allogeneic hematopoietic cell transplantation for XIAP deficiency: an international survey reveals poor outcomes.
Marsh R, Rao K, Satwani P, Lehmberg K, Müller I, Li D, Kim M, Fischer A, Latour S, Sedlacek P, Barlogis V, Hamamoto K, Kanegane H, Milanovich S, Margolis D, Dimmock D, Casper J, Douglas D, Amrolia P, Veys P, Kumar A, Jordan M, Bleesing J, Filipovich A
BLOOD. 2013;121(6):877-883.

Outcome of allogeneic SCT in patients with chronic myeloid leukemia in the era of tyrosine kinase inhibitor therapy.
Oyekunle A, Zander A, Binder M, Ayuketang F, Zabelina T, Christopeit M, Stübig T, Alchalby H, Schafhausen P, Lellek H, Wolschke C, Müller I, Bacher U, Kröger N
ANN HEMATOL. 2013;92(4):487-496.

2012

Defibrotide for prophylaxis of hepatic veno-occlusive disease in paediatric haemopoietic stem-cell transplantation: an open-label, phase 3, randomised controlled trial.
Corbacioglu S, Cesaro S, Faraci M, Valteau-Couanet D, Gruhn B, Rovelli A, Boelens J, Hewitt A, Schrum J, Schulz A, Müller I, Stein J, Wynn R, Greil J, Sykora K, Matthes-Martin S, Führer M, O'Meara A, Toporski J, Sedlacek P, Schlegel P, Ehlert K, Fasth A, Winiarski J, Arvidson J, Mauz-Körholz C, Ozsahin H, Schrauder A, Bader P, Massaro J, D'Agostino R, Hoyle M, Iacobelli M, Debatin K, Peters C, Dini G
LANCET. 2012;379(9823):1301-1309.

Caspofungin as antifungal prophylaxis in pediatric patients undergoing allogeneic hematopoietic stem cell transplantation: a retrospective analysis
Döring M, Hartmann U, Erbacher A, Lang P, Handgretinger R, Müller I
BMC INFECT DIS. 2012;12:151.

Analysis of posaconazole as oral antifungal prophylaxis in pediatric patients under 12 years of age following allogeneic stem cell transplantation.
Döring M, Müller C, Johann P, Erbacher A, Kimmig A, Schwarze C, Lang P, Handgretinger R, Müller I
BMC INFECT DIS. 2012;12:263.

Eradication of pulmonary aspergillosis in an adolescent patient undergoing three allogeneic stem cell transplantations for acute lymphoblastic leukemia.
Döring M, Zierl A, Mezger M, Lang P, Handgretinger R, Müller I
Case Rep Transplant. 2012;2012:672923.

Siglec-7 tetramers characterize B-cell subpopulations and leukemic blasts.
Gieseke F, Mang P, Viebahn S, Sonntag I, Kruchen A, Erbacher A, Pfeiffer M, Handgretinger R, Müller I
EUR J IMMUNOL. 2012;42(8):2176-2186.

Basic biology and clinical application of multipotent mesenchymal stromal cells: from bench to bedside
Kuçi S, Henschler R, Müller I, Biagi E, Meisel R
Stem Cells Int. 2012;2012:185943.

IL-15-stimulated CD3/CD19-depleted stem-cell boosts in relapsed pediatric patients after haploidentical SCT.
Pfeiffer M, Schumm M, Müller I, Handgretinger R, Lang P
LEUKEMIA. 2012;26(11):2435-2439.

2011

Bone regeneration: stem cell therapies and clinical studies in orthopaedics and traumatology
Gómez-Barrena E, Rosset P, Müller I, Giordano R, Bunu C, Layrolle P, Konttinen Y, Luyten F
J CELL MOL MED. 2011;15(6):1266-86.

Increased cyclosporine concentrations in the absence of cyclosporine administration.
Peter A, Shipkova M, Wieland E, Schleicher E, Müller I
CLIN CHEM. 2011;57(5):670-673.

Mesenchymal stromal cells for treatment of steroid-refractory GvHD: a review of the literature and two pediatric cases.
Wernicke C, Grunewald T, Juenger H, Kuci S, Kuci Z, Koehl U, Müller I, Doering M, Peters C, Lawitschka A, Kolb H, Bader P, Burdach S, von Luettichau I
Int Arch Med. 2011;4(1):27.

2010

Long-term human CD34+ stem cell-engrafted nonobese diabetic/SCID/IL-2R gamma(null) mice show impaired CD8+ T cell maintenance and a functional arrest of immature NK cells
André M, Erbacher A, Gille C, Schmauke V, Goecke B, Hohberger A, Mang P, Wilhelm A, Müller I, Herr W, Lang P, Handgretinger R, Hartwig U
J IMMUNOL. 2010;185(5):2710-20.

Human multipotent mesenchymal stromal cells use galectin-1 to inhibit immune effector cells
Gieseke F, Böhringer J, Bussolari R, Dominici M, Handgretinger R, Müller I
BLOOD. 2010;116(19):3770-9.

Successful autologous stem cell transplantation in two patients with juvenile dermatomyositis
Holzer U, van Royen-Kerkhof A, van der Torre P, Kuemmerle-Deschner J, Well C, Handgretinger R, Müller I, Wulffraat N
SCAND J RHEUMATOL. 2010;39(1):88-92.

Low physiologic oxygen tensions reduce proliferation and differentiation of human multipotent mesenchymal stromal cells
Holzwarth C, Vaegler M, Gieseke F, Pfister S, Handgretinger R, Kerst G, Müller I
BMC CELL BIOL. 2010;11:11.

Tumour stromal cells derived from paediatric malignancies display MSC-like properties and impair NK cell cytotoxicity
Johann P, Vaegler M, Gieseke F, Mang P, Armeanu-Ebinger S, Kluba T, Handgretinger R, Müller I
BMC CANCER. 2010;10:501.

Reconstitution of natural killer cell receptors influences natural killer activity and relapse rate after haploidentical transplantation of T- and B-cell depleted grafts in children
Pfeiffer M, Feuchtinger T, Teltschik H, Schumm M, Müller I, Handgretinger R, Lang P
HAEMATOLOGICA. 2010;95(8):1381-8.

Chronic inflammatory bowel disease as key manifestation of atypical ARTEMIS deficiency
Rohr J, Pannicke U, Döring M, Schmitt-Graeff A, Wiech E, Busch A, Speckmann C, Müller I, Lang P, Handgretinger R, Fisch P, Schwarz K, Ehl S
J CLIN IMMUNOL. 2010;30(2):314-20.

Letzte Aktualisierung aus dem FIS: 20.07.2018 - 00:03 Uhr