Eine Auwahl an Publikationen zu den Forschungsschwerpunkten des IOBM:

Wnt1 als Knochen-aufbauendes Molekül.

Ein interdisziplinäres Ärzte- und Forscherteam hat basierend auf Erkenntnissen aus dem National Bone Board und unter Federführung des IOBM den löslichen Liganden Wnt1 als osteo-anaboles Molekül identifizert, welches unabhängig von dem klassischen Co-Rezeptor Lrp5 wirken kann.
Wir freuen uns allen Interessierten die vollständige Originalpublikation, die mit dem Titel "Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand" in der renommierten Fachzeitschrift Science Translational Medicine veröffentlicht wurde, kostenfrei unter dem folgendem Link zum Download anbieten zu können: Volltext

Aus der Forschung

Magensäure ist wichtig

Vitamin D Mindestmenge


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Mechanical induction of osteoanabolic Wnt1 promotes osteoblast differentiation via Plat
Ahmad M, Haffner-Luntzer M, Schoppa A, Najafova Z, Lukic T, Yorgan T, Amling M, Schinke T, Ignatius A
FASEB J. 2024;38(4):.

Bisphosphonate Use and Periprosthetic Fractures
Alimy A, Beil F, Amling M, Rolvien T
J ARTHROPLASTY. 2024;39(1):e1-e2.

Functional analysis of postural spinal and pelvic parameters using static and dynamic spinometry
Bode T, Zoroofchi S, Vettorazzi E, Droste J, Welsch G, Schwesig R, Marshall R
HELIYON. 2024;10(7):e29239.

Lysosomal enzyme trafficking: from molecular mechanisms to human diseases
Braulke T, Carette J, Palm W
TRENDS CELL BIOL. 2024;34(3):198-210.

Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development
Brylka L, Alimy A, Tschaffon-Müller M, Jiang S, Ballhause T, Baranowsky A, von Kroge S, Delsmann J, Pawlus E, Eghbalian K, Püschel K, Schoppa A, Haffner-Luntzer M, Beech D, Beil F, Amling M, Keller J, Ignatius A, Yorgan T, Rolvien T, Schinke T
BONE RES. 2024;12(1):12.

Lower microhardness along with less heterogeneous mineralization in the femoral neck of individuals with type 2 diabetes mellitus indicates higher fracture risk
Cirovic A, Schmidt F, Vujacic M, Sihota P, Petrovic B, Zivkovic V, Bascarevic Z, Nikolic S, Djonic D, Djuric M, Busse B, Milovanovic P
JBMR PLUS. 2024;8(3):ziae005.

Alterations in compositional and cellular properties of the subchondral bone are linked to cartilage degeneration in hip osteoarthritis
Delsmann J, Eissele J, Simon A, Alimy A, von Kroge S, Mushumba H, Püschel K, Busse B, Ries C, Amling M, Beil F, Rolvien T
OSTEOARTHR CARTILAGE. 2024;32(5):535-547.

Age-related changes in the midpalatal suture: Comparison between CBCT staging and bone micromorphology
Georgi G, Knauth S, Hirsch E, Schulz-Kornas E, Kahl-Nieke B, Püschel K, Amling M, Koehne T, Korbmacher-Steiner H, Petersen J
BONE. 2024;179:.

An Additional Lrp4 High Bone Mass Mutation Mitigates the Sost-Knockout Phenotype in Mice by Increasing Bone Remodeling
Hendrickx G, Boudin E, Mateiu L, Yorgan T, Steenackers E, Kneissel M, Kramer I, Mortier G, Schinke T, Van Hul W
CALCIFIED TISSUE INT. 2024;114(2):171-181.

Pronounced cortical porosity and sex-specific patterns of increased bone and osteocyte lacunar mineralization characterize the human distal fibula with aging
Hering R, von Kroge S, Delsmann J, Simon A, Ondruschka B, Püschel K, Schmidt F, Rolvien T
BONE. 2024;182:117068.

Patient experiences of interprofessional collaboration and intersectoral communication in rare disease healthcare in Germany - a mixed-methods study
Inhestern L, Otto R, Brandt M, Zybarth D, Oheim R, Schüler H, Mir T, Tsiakas K, Dibaj P, Zschüntzsch J, Okun P, Hegenbart U, Sommerburg O, Schramm C, Weiler-Normann C, Härter M, Bergelt C
ORPHANET J RARE DIS. 2024;19(1):197.

Increased β2-adrenergic signaling promotes fracture healing through callus neovascularization in mice
Jahn D, Knapstein P, Otto E, Köhli P, Sevecke J, Graef F, Graffmann C, Fuchs M, Jiang S, Rickert M, Erdmann C, Appelt J, Revend L, Küttner Q, Witte J, Rahmani A, Duda G, Xie W, Donat A, Schinke T, Ivanov A, Tchouto M, Beule D, Frosch K, Baranowsky A, Tsitsilonis S, Keller J
SCI TRANSL MED. 2024;16(743):eadk9129.

Hereditary hypophosphatemic rickets with hypercalciuria (HHRH), a complex disorder in need of precision medicine
Schinke T, Oheim R
KIDNEY INT. 2024;105(5):927-929.

Osteomodulin deficiency in mice causes a specific reduction of transversal cortical bone size
Zhao W, von Kroge S, Jadzic J, Milovanovic P, Sihota P, Luther J, Brylka L, von Brackel F, Bockamp E, Busse B, Amling M, Schinke T, Schinke T
J BONE MINER RES. 2024 [Epub ahead of print].

On the fracture behavior of cortical bone microstructure: The effects of morphology and material characteristics of bone structural components
Allahyari P, Silani M, Yaghoubi V, Milovanovic P, Schmidt F, Busse B, Qwamizadeh M

CNS Manifestations in Mucolipidosis Type II-A Retrospective Analysis of Longitudinal Data on Neurocognitive Development and Neuroimaging in Eleven Patients
Ammer L, Täuber K, Perez A, Dohrmann T, Denecke J, Santer R, Blümlein U, Ozga A, Pohl S, Muschol N
J CLIN MED. 2023;12(12):.

Fracture healing in a mouse model of Hajdu–Cheney-Syndrome with high turnover osteopenia results in decreased biomechanical stability
Ballhause T, Jiang S, Xie W, Sevecke J, Dowling C, Dust T, Brandt S, Mertens P, Yorgan T, Schinke T, Frosch K, Baranowsky A, Keller J
SCI REP-UK. 2023;13(1):11418.

Comparison of Motion Grading in 1,000 Patients by First- and Second-Generation HR-pQCT: A Propensity Score Matched Cohort Study
Bartosik M, Simon A, Strahl A, Oheim R, Amling M, Schmidt F
CALCIFIED TISSUE INT. 2023;113(6):597-608.

Efficacy of zoledronic acid for the elimination of disseminated tumor cells in a clinically relevant, spontaneously metastatic prostate cancer xenograft model
Böckelmann L, Freytag V, Ahlers A, Maar H, Gosau T, Baranowsky A, Schmitz R, Pantel K, Schumacher U, Haider M, Lange T
BONE. 2023;171:116741.

Mice heterozygous for an osteogenesis imperfecta-linked MBTPS2 variant display a compromised subchondral osteocyte lacunocanalicular network associated with abnormal articular cartilage
Danyukova T, Alimy A, Velho R, Yorgan T, Di Lorenzo G, von Kroge S, Tidow H, Wiegert J, Hermans-Borgmeyer I, Schinke T, Rolvien T, Pohl S
BONE. 2023;177:.

Bone mineral density and microarchitecture change during skeletal growth in harbor seals (Phoca vitulina) from the German coast
Delsmann J, Schmidt B, Oheim R, Amling M, Rolvien T, Siebert U
SCI REP-UK. 2023;13(1):.

Cholesteatoma Severely Impacts the Integrity and Bone Material Quality of the Incus
Delsmann M, Bonik P, Ocokoljic A, Häussler S, Püschel K, Praetorius M, Amling M, Peichl J, Rolvien T
CALCIFIED TISSUE INT. 2023;113(6):609-617.

Radiolucent zones of biodegradable magnesium-based screws in children and adolescents-a radiographic analysis
Delsmann M, Stürznickel J, Kertai M, Stücker R, Rolvien T, Rupprecht M
ARCH ORTHOP TRAUM SU. 2023;143(5):2297-2305.

Fractal analysis of the mandible cortical bone: correlation among fractal dimension values obtained by two processing methods from periapical radiograph and micro-computed tomography with cone-beam computed tomography
de Oliveira Loures A, de Abreu M, Devito K, Grisolia-Seifert E, Jähn-Rickert K, Rabelo G
RADIAT ENVIRON BIOPH. 2023;62(4):511-518.

The selective norepinephrine reuptake inhibitor reboxetine promotes late-stage fracture healing in mice
Donat A, Jiang S, Xie W, Knapstein P, Albertsen L, Kokot J, Sevecke J, Augustin R, Jahn D, Yorgan T, Frosch K, Tsitsilonis S, Baranowsky A, Keller J
ISCIENCE. 2023;26(10):.

Osteocyte apoptosis and cellular micropetrosis signify skeletal aging in type 1 diabetes
Dragoun Kolibová S, Wölfel E, Hemmatian H, Milovanovic P, Mushumba H, Wulff B, Neidhardt M, Püschel K, Failla A, Vlug A, Schlaefer A, Ondruschka B, Amling M, Hofbauer L, Rauner M, Busse B, Jähn-Rickert K
ACTA BIOMATER. 2023;162:254-265.

Utility and Limitations of TALLYHO/JngJ as a Model for Type 2 Diabetes-Induced Bone Disease
Emini L, Salbach-Hirsch J, Krug J, Jähn-Rickert K, Busse B, Rauner M, Hofbauer L
JBMR PLUS. 2023;7(12):.

Wnt1 Boosts Fracture Healing by Enhancing Bone Formation in the Fracture Callus
Haffner-Luntzer M, Ragipoglu D, Ahmad M, Schoppa A, Steppe L, Fischer V, Luther J, Yorgan T, Bockamp E, Amling M, Schinke T, Ignatius A
J BONE MINER RES. 2023;38(5):749-764.

TMCO3, a Putative K+ :Proton Antiporter at the Golgi Apparatus, Is Important for Longitudinal Growth in Mice and Humans
Holling T, Brylka L, Scholz T, Bierhals T, Herget T, Meinecke P, Schinke T, Oheim R, Kutsche K
J BONE MINER RES. 2023;38(9):1334-1349.

Increased beta2-adrenergic signaling is a targetable stimulus essential for bone healing by promoting callus neovascularization
Jahn D, Knapstein P, Otto E, Köhli P, Sevecke J, Graef F, Graffmann C, Fuchs M, Jiang S, Rickert M, Erdmann C, Appelt J, Revend L, Küttner Q, Witte J, Rahmani A, Duda G, Xie W, Donat A, Schinke T, Ivanov A, Tchouto M, Beule D, Frosch K, Baranowsky A, Tsitsilonis S, Keller J
bioRxiv. 2023.

Impact of polyethylene glenoid cementation technique on cement mantle integrity and stability after cyclic loading: a computed tomography and biomechanical study
Kasten P, Jandl N, Zeifang F, Dallmann F, Jakobs S, Stalder K, Niemeier A
J SHOULDER ELB SURG. 2023;32(2):383-391.

20-Jahres-Ergebnisse der Verbundfestigkeit einer aufgesinterten 3-D-Titannetzbeschichtung von 31 Hüftpfannen
Koch K, Nolte I, Hahn M, Becker A
Z ORTHOP UNFALLCHIR. 2023 [Epub ahead of print].

Analysis of Three-Dimensional Bone Microarchitecture of the Axis Exposes Pronounced Regional Heterogeneity Associated with Clinical Fracture Patterns
Koepke L, Kroge S, Heuer A, Kammal A, Ondruschka B, Rolvien T, Viezens L
CALCIFIED TISSUE INT. 2023;112(5):563-572.

Cortical microarchitecture and remodeling-associated gene expression related to oral cancer prognosis
Lopes D, Patricio É, Assis N, Coutinho-Camillo C, Alves F, Kowalski L, Jähn-Rickert K, Busse B, Rabelo G
BRAZ ORAL RES. 2023;37:.

Epidemiology of Tumor-Induced Osteomalacia in Germany Based on Real World Data
May M, Oheim R, Bovy L, Doess A, Maessen D, Neukirch B, Norris R, Williams A, Abrahamsen B
CALCIFIED TISSUE INT. 2023;113(6):630-639.

Keratinocyte-derived S100A9 modulates neutrophil infiltration and affects psoriasis-like skin and joint disease
Mellor L, Gago-Lopez N, Bakiri L, Schmidt F, Busse B, Rauber S, Jimenez M, Megías D, Oterino-Soto S, Sanchez-Prieto R, Grivennikov S, Pu X, Oxford J, Ramming A, Schett G, Wagner E
ANN RHEUM DIS. 2023;81(10):1400-1408.

Effects of more natural housing conditions on the muscular and skeletal characteristics of female C57BL/6J mice
Mieske P, Scheinpflug J, Yorgan T, Brylka L, Palme R, Hobbiesiefken U, Preikschat J, Lewejohann L, Diederich K
LAB ANIM RES. 2023;39(1):9.

Micropetrosis: Osteocyte Lacunar Mineralization in Aging and Disease
Milovanovic P, Busse B
CURR OSTEOPOROS REP. 2023;21(6):750-757.

Mechanical-induced bone remodeling does not depend on Piezo1 in dentoalveolar hard tissue
Nottmeier C, Lavicky J, Gonzalez Lopez M, Knauth S, Kahl-Nieke B, Amling M, Schinke T, Helms J, Krivanek J, Koehne T, Petersen J
SCI REP-UK. 2023;13(1):.

Non-functional ubiquitin C-terminal hydrolase L1 drives podocyte injury through impairing proteasomes in autoimmune glomerulonephritis
Reichelt J, Sachs W, Frömbling S, Fehlert J, Studencka-Turski M, Betz A, Loreth D, Blume L, Witt S, Pohl S, Brand J, Czesla M, Knop J, Florea B, Zielinski S, Sachs M, Hoxha E, Hermans-Borgmeyer I, Zahner G, Wiech T, Krüger E, Meyer-Schwesinger C
NAT COMMUN. 2023;14(1):2114.

Denosumab and muscle performance
Rolvien T, Rupp T, Strahl A, Amling M
OSTEOPOROSIS INT. 2023;34(1):211-212.

Ex Vivo Model of Neuroblastoma Plasticity
Schäfer P, Muhs S, Turnbull L, Garwal P, Maar H, Yorgan T, Tolosa E, Lange T, Windhorst S
CANCERS. 2023;15(4):.

Age-, sex- and subregion-specific properties of distal fibular microarchitecture and strength: an ex vivo HR-pQCT study
Schlickewei C, Schweizer C, Püschel K, Ondruschka B, Kleinertz H, Barg A, Rolvien T, Stürznickel J
J ORTHOP RES. 2023;41(2):355-363.

Radial HR-pQCT and Finite Element Analysis in HPP Patients are Superior in Identifying Susceptibility to Fracture-Associated Skeletal Affections Compared to DXA and Laboratory Tests
Schmidt F, Schmidt C, Delsmann J, Amling M, Barvencik F
CALCIFIED TISSUE INT. 2023;112(6):691-703.

Empfehlungen zur Versorgung von Patient:innen mit FOP
Seefried L, Banholzer D, Fischer R, Grafe I, Hüning I, Morhart R, Oheim R, Semler O, Siggelkow H, Stockklausner C, Hoyer-Kuhn H
ORTHOPADIE. 2023;52(11):924-930.

Why animal experiments are still indispensable in bone research: A statement by the European Calcified Tissue Society
Stein M, Elefteriou F, Busse B, Fiedler I, Kwon R, Farell E, Ahmad M, Ignatius A, Grover L, Geris L, Tuckermann J
J BONE MINER RES. 2023;38(8):1045-1061.

Dynamics of Skeletal Status under Optimized Management during Subsequent Pregnancy in Three Women with a History of Pregnancy- and Lactation-Associated Osteoporosis Carrying pathogenic Variants in WNT1 and LRP5
Stürznickel J, Butscheidt S, Amling M, Oheim R
JBMR PLUS. 2023;7(8):.

AXIN1 bi-allelic variants disrupting the C-terminal DIX domain cause craniometadiaphyseal osteosclerosis with hip dysplasia
Terhal P, Venhuizen A, Lessel D, Tan W, Alswaid A, Grün R, Alzaidan H, von Kroge S, Ragab N, Hempel M, Kubisch C, Novais E, Cristobal A, Tripolszki K, Bauer P, Fischer-Zirnsak B, Nievelstein R, van Dijk A, Nikkels P, Oheim R, Hahn H, Bertoli-Avella A, Maurice M, Kornak U
AM J HUM GENET. 2023;110(9):1470-1481.

Zebrafish Tric-b is required for skeletal development and bone cells differentiation
Tonelli F, Leoni L, Daponte V, Gioia R, Cotti S, Fiedler I, Larianova D, Willaert A, Coucke P, Villani S, Busse B, Besio R, Rossi A, Witten P, Forlino A

Do Clinical Parameters Reflect Local Bone Metabolism in Heterotopic Ossification After Septic or Aseptic THA?
von Kroge S, Büyükyilmaz Z, Alimy A, Hubert J, Citak M, Amling M, Beil F, Ohlmeier M, Rolvien T
CLIN ORTHOP RELAT R. 2023;481(10):2029-2041.

Zinc and vitamin D deficiency and supplementation in hypophosphatasia patients: A retrospective study
Wiedemann P, Schmidt F, Amling M, Yorgan T, Barvencik F
BONE. 2023;175:.

When Cortical Bone Matrix Properties Are Indiscernible between Elderly Men with and without Type 2 Diabetes, Fracture Resistance Follows Suit
Wölfel E, Bartsch B, Koldehoff J, Fiedler I, Dragoun-Kolibova S, Schmidt F, Krug J, Lin M, Püschel K, Ondruschka B, Zimmermann E, Jelitto H, Schneider G, Gludovatz B, Busse B
JBMR PLUS. 2023;7(12):e10839.

Reduced Bone Mass and Increased Osteocyte Tartrate-Resistant Acid Phosphatase (TRAP) Activity, But Not Low Mineralized Matrix Around Osteocyte Lacunae, Are Restored After Recovery From Exogenous Hyperthyroidism in Male Mice
Wölfel E, Lademann F, Hemmatian H, Blouin S, Messmer P, Hofbauer L, Busse B, Rauner M, Jähn-Rickert K, Tsourdi E
J BONE MINER RES. 2023;38(1):131-143.

Effects of Infantile Hypophosphatasia on Human Dental Tissue
Wölfel E, von Kroge S, Matthies L, Köhne T, Petz K, Beikler T, Schmid-Herrmann C, Kahl-Nieke B, Tsiakas K, Santer R, Muschol N, Herrmann J, Busse B, Amling M, Rolvien T, Jandl N, Barvencik F
CALCIFIED TISSUE INT. 2023;112(3):308-319.

Forschung: Vom Feldscher zum Unfallchirurgen des 21. Jahrhunderts
Amling M
UNFALLCHIRURGIE. 2022;125(10):767-770.

Procalcitonin is expressed in osteoblasts and limits bone resorption through inhibition of macrophage migration during intermittent PTH treatment
Baranowsky A, Jahn D, Jiang S, Yorgan T, Ludewig P, Appelt J, Albrecht K, Otto E, Knapstein P, Donat A, Winneberger J, Rosenthal L, Köhli P, Erdmann C, Fuchs M, Frosch K, Tsitsilonis S, Amling M, Schinke T, Keller J
BONE RES. 2022;10(1):.

G6b-B regulates an essential step in megakaryocyte maturation
Becker I, Nagy Z, Manukjan G, Haffner-Luntzer M, Englert M, Heib T, Vögtle T, Gross C, Bharti R, Dietrich S, Mott K, Heck J, Stegmaier S, Baranowsky A, Schinke T, Schlegel N, Heckel T, Stegner D, Pleines I, Ignatius A, Schulze H, Nieswandt B
BLOOD ADV. 2022;6(10):3155-3161.

Tumorlokalisation und Therapie der onkogenen Osteomalazie
Beil F, Stürznickel J, Rolvien T, Amling M, Oheim R
Z RHEUMATOL. 2022;81(3):182-188.

Spine Metastases in Immunocompromised Mice after Intracardiac Injection of MDA-MB-231-SCP2 Breast Cancer Cells
Brylka L, Jähn-Rickert K, Baranowsky A, Neven M, Horn M, Yorgan T, Wikman H, Werner S, Lübke A, Amling M, Busse B, Pantel K, Schinke T
CANCERS. 2022;14(3):.

P-Type Lectins
Dahms N, Braulke T, Varki A
2022. Essentials of Glycobiology. Varki A (Hrsg.). 4. Aufl. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press, 443 - 454.

Site-1 and site-2 proteases: A team of two in regulated proteolysis
Danyukova T, Schöneck K, Pohl S
BBA-MOL CELL RES. 2022;1869(1):119138.

Prevention of Hypomineralization In Auditory Ossicles of Vitamin D Receptor (Vdr) Deficient Mice
Delsmann M, Peichl J, Yorgan T, Beil F, Amling M, Demay M, Rolvien T

Prevalence of osteoporosis and osteopenia in elderly patients scheduled for total knee arthroplasty
Delsmann M, Schmidt C, Mühlenfeld M, Jandl N, Boese C, Beil F, Rolvien T, Ries C
ARCH ORTHOP TRAUM SU. 2022;142(12):3957-3964.

Mechanical forces couple bone matrix mineralization with inhibition of angiogenesis to limit adolescent bone growth
Dzamukova M, Brunner T, Miotla-Zarebska J, Heinrich F, Brylka L, Mashreghi M, Kusumbe A, Kühn R, Schinke T, Vincent T, Löhning M
NAT COMMUN. 2022;13(1):3059.

Oral HRAS Mutation in Orofacial Nevus Sebaceous Syndrome (Schimmelpenning-Feuerstein-Mims-Syndrome): A Case Report With a Literature Survey
Friedrich R, Gosau M, Luebke A, Hagel C, Kohlrusch F, Hahn M, von Kroge S, Hahn J, Wieland I, Zenker M
IN VIVO. 2022;36(1):274-293.

Ja, vom Lebensretter zur Gefahr – „Out of position“ macht den Unterschied
Hahn M, Dreimann M, Matschke J, Lohner L, Püschel K
RECHTSMEDIZIN. 2022;32(5):410-411.

Influence of Fracture Reduction on the Functional Outcome after Intramedullary Nail Osteosynthesis in Proximal Humerus Fractures
Hättich A, Harloff T, Sari H, Schlickewei C, Cramer C, Strahl A, Frosch K, Mader K, Klatte T
J CLIN MED. 2022;11(22):.

Bone fragility in diabetes: novel concepts and clinical implications
Hofbauer L, Busse B, Eastell R, Ferrari S, Frost M, Müller R, Burden A, Rivadeneira F, Napoli N, Rauner M
LANCET DIABETES ENDO. 2022;10(3):207-220.

A homozygous hypomorphic BNIP1 variant causes an increase in autophagosomes and reduced autophagic flux and results in a spondylo-epiphyseal dysplasia
Holling T, Bhavani G, von Elsner L, Shah H, Kausthubham N, Bhattacharyya S, Shukla A, Mortier G, Schinke T, Danyukova T, Pohl S, Kutsche K, Girisha K
HUM MUTAT. 2022;43(5):625-642.

The Bone Microarchitecture Deficit in Patients with Hemophilia Is Influenced by Arthropathy, Hepatitis C Infection, and Physical Activity
Holstein K, Witt L, Matysiak A, Schmidt C, Barvencik F, Amling M, Rolvien T, Langer F
THROMB HAEMOSTASIS. 2022;122(5):692-702.

Impact of the Endocannabinoid System on Bone Formation and Remodeling in p62 KO Mice
Keller C, Yorgan T, Rading S, Schinke T, Karsak M

Micropetrosis – Occlusion of Osteocyte Lacunae
Kolibová S, Busse B, Jähn-Rickert K
OSTEOLOGIE. 2022;31(04):280-288.

17th German Spine Congress, Annual Meeting of the German Spine Society: The three-dimensional bone microstructure of the axis and clinical implications
Köpke L, von Kroge S, Heuer A, Kammal M, Ondruschka B, Rolvien T, Viezens L
EUR SPINE J. 2022;31(11):3240-3240.

MODL-03. Establishment of intraventricular Shh inhibition as a therapeutic option for young patients with medulloblastoma
Kresbach C, Schoof M, Holst L, Leven T, Yorgan T, Wrzeszcz A, Rutkowski S, Schüller U
NEURO-ONCOLOGY. 2022;24(S1):i168.

Systemic calcitonin gene-related peptide receptor antagonism decreases survival in a porcine model of polymicrobial sepsis
Messerer D, Datzmann T, Baranowsky A, Peschel L, Hoffmann A, Gröger M, Amling M, Wepler M, Nussbaum B, Jiang S, Knapstein P, Donat A, Calzia E, Radermacher P, Keller J
BRIT J ANAESTH. 2022;128(5):864-873.

Selective Inner Hair Cell Loss in a Neonate Harbor Seal (Phoca vitulina)
Morell M, Rojas L, Haulena M, Busse B, Siebert U, Shadwick R, Raverty S
ANIMALS-BASEL. 2022;12(2):.

Early enzyme replacement therapy prevents dental and craniofacial abnormalities in a mouse model of mucopolysaccharidosis type VI
Nagpal R, Georgi G, Knauth S, Schmid-Herrmann C, Muschol N, Braulke T, Kahl-Nieke B, Amling M, Schinke T, Koehne T, Petersen J
FRONT PHYSIOL. 2022;13:.

Genetic Diagnostics in Routine Osteological Assessment of Adult Low Bone Mass Disorders
Oheim R, Tsourdi E, Seefried L, Beller G, Schubach M, Vettorazzi E, Stürznickel J, Rolvien T, Ehmke N, Delsmann A, Genest F, Krüger U, Zemojtel T, Barvencik F, Schinke T, Jakob F, Hofbauer L, Mundlos S, Kornak U
J CLIN ENDOCR METAB. 2022;107(7):e3048-e3057.

Orthogonally-polarized excitation for improved two-photon and second-harmonic-generation microscopy, applied to neurotransmitter imaging with GPCR-based sensors
Pulin M, Stockhausen K, Masseck O, Kubitschke M, Busse B, Wiegert J, Oertner T
BIOMED OPT EXPRESS. 2022;13(2):777-790.

A machine learning approach to identify risk factors for running-related injuries: study protocol for a prospective longitudinal cohort trial
Rahlf A, Hoenig T, Stürznickel J, Cremans K, Fohrmann D, Sanchez-Alvarado A, Rolvien T, Hollander K
BMC SPORTS SCI MED R. 2022;14(1):.

The human disease gene LYSET is essential for lysosomal enzyme transport and viral infection
Richards C, Jabs S, Qiao W, Varanese L, Schweizer M, Mosen P, Riley N, Klüssendorf M, Zengel J, Flynn R, Rustagi A, Widen J, Peters C, Ooi Y, Xie X, Shi P, Bartenschlager R, Puschnik A, Bogyo M, Bertozzi C, Blish C, Winter D, Nagamine C, Braulke T, Carette J
SCIENCE. 2022;378(6615):.

Pulmonary cement embolism is frequently observed but not a contributing factor for death in patients with cemented total hip and knee arthroplasty: a postmortem study
Ritter J, Hubert J, Kniep I, Beil F, Rolvien T, Püschel K
INT ORTHOP. 2022;46(6):1225-1232.

Disuse Osteoporosis: Clinical and Mechanistic Insights
Rolvien T, Amling M
CALCIFIED TISSUE INT. 2022;110(5):592-604.

A finite element study on femoral locking compression plate design using genetic optimization method
Rostamian R, Silani M, Ziaei-Rad S, Busse B, Qwamizadeh M, Rabczuk T

Clinical features of methotrexate osteopathy in rheumatic musculoskeletal disease: A systematic review
Ruffer N, Krusche M, Beil F, Amling M, Kötter I, Rolvien T
SEMIN ARTHRITIS RHEU. 2022;52:151952.

Bilateral Stress Fractures of the Lower Extremity in Methotrexate Osteopathy
Ruffer N, Stürznickel J, Rolvien T
DTSCH ARZTEBL INT. 2022;119(13):.

Beneficial effects of denosumab on muscle performance in patients with low BMD: a retrospective, propensity score-matched study
Rupp T, von Vopelius E, Strahl A, Oheim R, Barvencik F, Amling M, Rolvien T
OSTEOPOROSIS INT. 2022;33(10):2177-2184.

Antibacterial properties of functionalized silk fibroin and sericin membranes for wound healing applications in oral and maxillofacial surgery
Schäfer S, Smeets R, Köpf M, Drinic A, Kopp A, Kröger N, Hartjen P, Assaf A, Aavani F, Beikler T, Peters U, Fiedler I, Busse B, Stürmer E, Vollkommer T, Gosau M, Fuest S
BIOMATER ADV. 2022;135:.

Similar Clinical Outcome in Locking and Conventional Plate Osteosynthesis for the Treatment of AO 44-B2 Ankle Fractures
Schagemann J, Neumann H, Schäfers J, Paech A, Wendlandt R, Oheim R, Schulz A
Foot & ankle specialist. 2022 [Epub ahead of print];19386400221136757.

Investigation of distal femur microarchitecture and factors influencing its deterioration: An ex vivo high-resolution peripheral quantitative computed tomography study
Schmidt C, Riedel C, Stürznickel J, Mushumba H, Delsmann M, Ries C, Kleiss S, Bannas P, Beil F, Amling M, Püschel K, Rolvien T, Hubert J
J ORTHOP RES. 2022;40(9):2057-2064.

Influence of X-rays and gamma-rays on the mechanical performance of human bone factoring out intraindividual bone structure and composition indices
Schmidt F, Hahn M, Stockhausen K, Rolvien T, Schmidt C, Knopp T, Schulze C, Püschel K, Amling M, Busse B
MATER TODAY BIO. 2022;13:.

Impact of test environment on the fracture resistance of cortical bone
Shin M, Zhang M, Vom Scheidt A, Pelletier M, Walsh W, Martens P, Kruzic J, Busse B, Gludovatz B
J MECH BEHAV BIOMED. 2022;129:105155.

Blast injury on harbour porpoises (Phocoena phocoena) from the Baltic Sea after explosions of deposits of World War II ammunition
Siebert U, Stürznickel J, Schaffeld T, Oheim R, Rolvien T, Prenger-Berninghoff E, Wohlsein P, Lakemeyer J, Rohner S, Aroha Schick L, Gross S, Nachtsheim D, Ewers C, Becher P, Amling M, Morell M
ENVIRON INT. 2022;159:.

Compartment-specific effects of muscle strength on bone microarchitecture in women at high risk of osteoporosis
Simon A, Schäfer H, Schmidt F, Stürznickel J, Amling M, Rolvien T
J CACHEXIA SARCOPENI. 2022;13(5):2310-2321.

New and innovative biomaterials, techniques and therapy concepts: Biologization in maxillofacial surgery, oral surgery and dentistry is in full swing. PRF, PRGF, PRP, blood plasma-stabilized augmentations, supplementation of micronutrients and vitamins - what opportunities do such "biological" approaches actually offer? We introduce them here
Smeets R, Henningsen A, Zernial O, Stürmer E, Fiedler I, Schäfer S, Gosau M, Gaudin R, Stolzer C, Reinelt A, Fuest S

Increased concentrations of conjugated bile acids are associated with osteoporosis in PSC patients
Stürznickel J, Behler-Janbeck F, Baranowsky A, Schmidt T, Schwinge D, John C, Lohse A, Schramm C, Heeren J, Schinke T, Amling M
SCI REP-UK. 2022;12(1):.

Clinical spectrum of Hereditary Hypophosphatemic rickets with Hypercalciuria (HHRH)
Stürznickel J, Heider F, Delsmann A, Gödel M, Grünhagen J, Huber T, Kornak U, Amling M, Oheim R
J BONE MINER RES. 2022;37(8):1580-1591.

Impaired Bone Microarchitecture at Distal Radial and Tibial Reference Locations Is Not Related to Injury Site in Athletes With Bone Stress Injury
Stürznickel J, Hinz N, Delsmann M, Hoenig T, Rolvien T
AM J SPORT MED. 2022;50(12):3381-3389.

Superior Bone Microarchitecture in Anatomic Versus Nonanatomic Fibular Drill Tunnels for Reconstruction of the Posterolateral Corner of the Knee
Stürznickel J, Schmidt F, Schweizer C, Mushumba H, Krause M, Püschel K, Rolvien T
ORTHOP J SPORTS MED. 2022;10(9):.

Characterization of hearing-impairment in Generalized Arterial Calcification of Infancy (GACI)
Theng E, Brewer C, Oheim R, Zalewski C, King K, Delsmann M, Rolvien T, Gafni R, Braddock D, Jeffrey Kim H, Ferreira C
ORPHANET J RARE DIS. 2022;17(1):.

Human engineered heart tissue transplantation in a guinea pig chronic injury model
von Bibra C, Shibamiya A, Geertz B, Querdel E, Köhne M, Stüdemann T, Starbatty J, Schmidt F, Hansen A, Hiebl B, Eschenhagen T, Weinberger F
J MOL CELL CARDIOL. 2022;166:1-10.

Impaired bone quality in the superolateral femoral neck occurs independent of hip geometry and bone mineral density
von Kroge S, Stürznickel J, Bechler U, Stockhausen K, Eissele J, Hubert J, Amling M, Beil F, Busse B, Rolvien T
ACTA BIOMATER. 2022;141:233-243.

wnt16 regulates spine and muscle morphogenesis through parallel signals from notochord and dermomyotome
Watson C, Tang W, Rojas M, Fiedler I, Morfin Montes de Oca E, Cronrath A, Callies L, Swearer A, Ahmed A, Sethuraman V, Addish S, Farr G, Gómez A, Rai J, Monstad-Rios A, Gardiner E, Karasik D, Maves L, Busse B, Hsu Y, Kwon R
PLOS GENET. 2022;18(11):.

Human tibial cortical bone with high porosity in type 2 diabetes mellitus is accompanied by distinctive bone material properties
Wölfel E, Fiedler I, Kolibova S, Krug J, Lin M, Yazigi B, Siebels A, Mushumba H, Wulff B, Ondruschka B, Püschel K, Glüer C, Jähn-Rickert K, Busse B
BONE. 2022;165:.

Dimorphic mechanisms of fragility in diabetes mellitus - the role of reduced collagen fibril deformation
Wölfel E, Schmidt F, Vom Scheidt A, Siebels A, Wulff B, Mushumba H, Ondruschka B, Püschel K, Scheijen J, Schalkwijk C, Vettorazzi E, Jähn-Rickert K, Gludovatz B, Schaible E, Amling M, Rauner M, Hofbauer L, Zimmermann E, Busse B
J BONE MINER RES. 2022;37(11):2259-2276.

Catalysis-independent ENPP1 protein signaling regulates mammalian bone mass
Zimmerman K, Li X, von Kroge S, Stabach P, Lester E, Chu E, Srivastava S, Somerman M, Tommasini S, Busse B, Schinke T, Carpenter T, Oheim R, Braddock D
J BONE MINER RES. 2022;37(9):1733-1749.

Is hematopoietic stem cell transplantation a therapeutic option for mucolipidosis type II?
Ammer L, Pohl S, Breyer S, Aries C, Denecke J, Perez A, Petzoldt M, Schrum J, Müller I, Muschol N

Relevance of Notch Signaling for Bone Metabolism and Regeneration
Ballhause T, Jiang S, Baranowsky A, Brandt S, Mertens P, Frosch K, Yorgan T, Keller J
INT J MOL SCI. 2021;22(3):.

Procalcitonin Exerts a Mediator Role in Septic Shock Through the Calcitonin Gene-Related Peptide Receptor
Baranowsky A, Appelt J, Kleber C, Lange T, Ludewig P, Jahn D, Pandey P, Keller D, Rose T, Schetler D, Braumüller S, Huber-Lang M, Tsitsilonis S, Yorgan T, Frosch K, Amling M, Schinke T, Keller J
CRIT CARE MED. 2021;49(1):e41-e52.

Challenges in the management of tumor-induced osteomalacia (TIO)
Brandi M, Clunie G, Houillier P, Jan de Beur S, Minisola S, Oheim R, Seefried L
BONE. 2021;152:116064.

Relevant genetic variants are common in women with pregnancy and lactation-associated osteoporosis (PLO) and predispose to more severe clinical manifestations
Butscheidt S, Tsourdi E, Rolvien T, Delsmann A, Stürznickel J, Barvencik F, Jakob F, Hofbauer L, Mundlos S, Kornak U, Seefried L, Oheim R
BONE. 2021;147:.

Allograft Chip Incorporation in Acetabular Reconstruction: Multiscale Characterization Revealing Osteoconductive Capacity
Butscheidt S, von Kroge S, Stürznickel J, Beil F, Gehrke T, Püschel K, Amling M, Hahn M, Rolvien T
J BONE JOINT SURG AM. 2021;103(21):1996-2005.

Role of c-Fos in orthodontic tooth movement: an in vivo study using transgenic mice
Decker M, Nottmeier C, Luther J, Baranowsky A, Kahl-Nieke B, Amling M, Schinke T, David J, Koehne T
CLIN ORAL INVEST. 2021;25(2):593-601.

Conductive hearing loss in the Hyp mouse model of X-linked hypophosphatemia is accompanied by hypomineralization of the auditory ossicles
Delsmann M, Seist R, Stürznickel J, Schmidt F, Mansour A, Kobelski M, Broocks G, Peichl J, Oheim R, Praetorius M, Schinke T, Amling M, Demay M, Stankovic K, Rolvien T
J BONE MINER RES. 2021;36(12):2317-2328.

High prevalence and undertreatment of osteoporosis in elderly patients undergoing total hip arthroplasty
Delsmann M, Strahl A, Mühlenfeld M, Jandl N, Beil F, Ries C, Rolvien T
OSTEOPOROSIS INT. 2021;32(8):1661-1668.

Muskuloskelettale Labordiagnostik im Leistungssport
Delsmann M, Stürznickel J, Amling M, Ueblacker P, Rolvien T
ORTHOPADE. 2021;50(9):700-712.

Skeletal Biology and Disease Modeling in Zebrafish
Dietrich K, Fiedler I, Kurzyukova A, López-Delgado A, McGowan L, Geurtzen K, Hammond C, Busse B, Knopf F
J BONE MINER RES. 2021;36(3):436-458.

Pathogenic variants in GNPTAB and GNPTG encoding distinct subunits of GlcNAc-1-phosphotransferase differentially impact bone resorption in patients with mucolipidosis type II and III
Di Lorenzo G, Westermann L, Schinke T, Stürznickel J, Ludwig N, Ammer L, Baranowsky A, Ahmadi S, Pourbarkhordariesfandabadi E, Breyer S, Board T, Foster A, Mercer J, Tylee K, Velho R, Schweizer M, Renné T, Braulke T, Randon D, Sperb-Ludwig F, de Camargo Pinto L, Moreno C, Cavalcanti D, Amling M, Kutsche K, Winter D, Muschol N, Schwartz I, Rolvien T, Danyukova T, Schinke T, Pohl S
GENET MED. 2021;23(12):2369-2377.

Mucolipidosis type II and type III: a systematic review of 843 published cases
Dogterom E, Wagenmakers M, Wilke M, Demirdas S, Muschol N, Pohl S, van der Meijden J, Rizopoulos D, van der Ploeg A, Oussoren E
GENET MED. 2021;23(11):2047-2056.

Response of the ENPP1-deficient skeletal phenotype to oral phosphate supplementation and/or enzyme replacement therapy: Comparative studies in Humans and Mice
Ferreira C, Kavanagh D, Oheim R, Zimmerman K, Stürznickel J, Li X, Stabach P, Rettig R, Calderone L, MacKichan C, Wang A, Hutchinson H, Nelson T, Tommassini S, von Kroge S, Fiedler I, Lester E, Moeckel G, Busse B, Schinke T, Carpenter T, Levine M, Horwowitz M, Braddock D
J BONE MINER RES. 2021;36(5):942-955.

Bone Phenotyping Approaches in Human, Mice and Zebrafish - Expert Overview of the EU Cost Action GEMSTONE ("GEnomics of MusculoSkeletal traits TranslatiOnal NEtwork")
Foessl I, Bassett J, Bjørnerem Å, Busse B, Calado Â, Chavassieux P, Christou M, Douni E, Fiedler I, Fonseca J, Hassler E, Högler W, Kague E, Karasik D, Khashayar P, Langdahl B, Leitch V, Lopes P, Markozannes G, McGuigan F, Medina-Gomez C, Ntzani E, Oei L, Ohlsson C, Szulc P, Tobias J, Trajanoska K, Tuzun Ş, Valjevac A, van Rietbergen B, Williams G, Zekic T, Rivadeneira F, Obermayer-Pietsch B

Neurofibromatosis Type 1 With Cherubism-like Phenotype, Multiple Osteolytic Bone Lesions of Lower Extremities, and Alagille-syndrome: Case Report With Literature Survey
Friedrich R, Zustin J, Luebke A, Rosenbaum T, Gosau M, Hagel C, Kohlrusch F, Wieland I, Zenker M
IN VIVO. 2021;35(3):1711-1736.

Cranial bone flap resorption-pathological features and their implications for clinical treatment
Göttsche J, Mende K, Schram A, Westphal M, Amling M, Regelsberger J, Sauvigny T, Hahn M
NEUROSURG REV. 2021;44(4):2253-2260.

Ein Airbag kann auch tödlich sein
Hahn M, Dreimann M, Matschke J, Lohner L, Püschel K

Reorganization of the osteocyte lacuno-canalicular network characteristics in tumor sites of an immunocompetent murine model of osteotropic cancers
Hemmatian H, Conrad S, Furesi G, Mletzko K, Krug J, Failla A, Kuhlmann J, Rauner M, Busse B, Jähn-Rickert K
BONE. 2021;152:.

Piezo1 Inactivation in Chondrocytes Impairs Trabecular Bone Formation
Hendrickx G, Fischer V, Liedert A, von Kroge S, Haffner-Luntzer M, Brylka L, Pawlus E, Schweizer M, Yorgan T, Baranowsky A, Rolvien T, Neven M, Schumacher U, Beech D, Amling M, Ignatius A, Schinke T
J BONE MINER RES. 2021;36(2):369-384.

Knockdown of AKT3 Activates HER2 and DDR Kinases in Bone-Seeking Breast Cancer Cells, Promotes Metastasis In Vivo and Attenuates the TGFβ/CTGF Axis
Hinz N, Baranowsky A, Horn M, Kriegs M, Sibbertsen F, Smit D, Clezardin P, Lange T, Schinke T, Jücker M
CELLS-BASEL. 2021;10(2):.

Autosomal recessive hypophosphatemic rickets type 2 (ARHR2) due to ENPP1-deficiency
Höppner J, Kornak U, Sinningen K, Rutsch F, Oheim R, Grasemann C
BONE. 2021;153:.

Potential Role of Perilacunar Remodeling in the Progression of Osteoporosis and Implications on Age-Related Decline in Fracture Resistance of Bone
Jähn-Rickert K, Zimmermann E
CURR OSTEOPOROS REP. 2021;19(4):391-402.

Diagnostic yield of cone beam computed tomography for small foreign body detection in the hand in comparison with radiography, MSCT and MRI: an ex vivo study
Jandl N, Rolvien T, Rupp T, Schumacher U, Püschel K, Maas K, Amling M, Henes F, Spink C
INJURY. 2021;52(10):2841-2847.

Genotype-Phenotype Associations in 72 Adults with Suspected ALPL-Associated Hypophosphatasia
Jandl N, Schmidt T, Rolvien T, Stürznickel J, Chrysostomou K, von Vopelius E, Volk A, Schinke T, Kubisch C, Amling M, Barvencik F
CALCIFIED TISSUE INT. 2021;108(3):288-301.

Temporomandibular Joint Osteoarthritis: Regenerative Treatment by a Stem Cell Containing Advanced Therapy Medicinal Product (ATMP)-An In Vivo Animal Trial
Köhnke R, Ahlers M, Birkelbach M, Ewald F, Krueger M, Fiedler I, Busse B, Heiland M, Vollkommer T, Gosau M, Smeets R, Rutkowski R
INT J MOL SCI. 2021;22(1):.

Bacterial adhesion characteristics on implant materials for intervertebral cages: titanium or PEEK for spinal infections?
Krätzig T, Mende K, Mohme M, von Kroge S, Stangenberg M, Dreimann M, Westphal M, Weisselberg S, Eicker S
EUR SPINE J. 2021;30(6):1774-1782.

Kresbach C, Schoof M, Leven T, Holst L, Yorgan T, Wrzeszcz A, Rutkowski S, Schüller U
NEURO-ONCOLOGY. 2021;23(Supplement_6):vi179.

Osteoblast-specific inactivation of p53 results in locally increased bone formation
Liao N, Koehne T, Tuckermann J, Triviai I, Amling M, David J, Schinke T, Luther J
PLOS ONE. 2021;16(11):e0249894.

Bone mineral density assessment by DXA in rheumatic patients with end-stage osteoarthritis undergoing total joint arthroplasty
Mühlenfeld M, Strahl A, Bechler U, Jandl N, Hubert J, Rolvien T
BMC MUSCULOSKEL DIS. 2021;22(1):173.

Wnt1 Promotes Cementum and Alveolar Bone Growth in a Time-Dependent Manner
Nottmeier C, Liao N, Simon A, Decker M, Luther J, Schweizer M, Yorgan T, Kaucka M, Bockamp E, Kahl-Nieke B, Amling M, Schinke T, Petersen J, Koehne T
J DENT RES. 2021;100(13):1501-1509.

In Vivo Analysis of the Biocompatibility and Bone Healing Capacity of a Novel Bone Grafting Material Combined with Hyaluronic Acid
Pröhl A, Batinic M, Alkildani S, Hahn M, Radenkovic M, Najman S, Jung O, Barbeck M
INT J MOL SCI. 2021;22(9):.

Perspective of the GEMSTONE Consortium on Current and Future Approaches to Functional Validation for Skeletal Genetic Disease Using Cellular, Molecular and Animal-Modeling Techniques
Rauner M, Foessl I, Formosa M, Kague E, Prijatelj V, Lopez N, Banerjee B, Bergen D, Busse B, Calado Â, Douni E, Gabet Y, Giralt N, Grinberg D, Lovsin N, Solan X, Ostanek B, Pavlos N, Rivadeneira F, Soldatovic I, van de Peppel J, van der Eerden B, van Hul W, Balcells S, Marc J, Reppe S, Søe K, Karasik D

Bone quality analysis of jaw bones in individuals with type 2 diabetes mellitus-post mortem anatomical and microstructural evaluation
Rodic T, Wölfel E, Milovanovic P, Fiedler I, Cvetkovic D, Jähn K, Amling M, Sopta J, Nikolic S, Zivkovic V, Busse B, Djuric M
CLIN ORAL INVEST. 2021;25(7):4377-4400.

Clinical and Radiological Characterization of Patients with Immobilizing and Progressive Stress Fractures in Methotrexate Osteopathy
Rolvien T, Jandl N, Stürznickel J, Beil F, Kötter I, Oheim R, Lohse A, Barvencik F, Amling M
CALCIFIED TISSUE INT. 2021;108(2):219-230.

Intraossäres Hibernom der Lendenwirbelsäule
Rolvien T, Stürznickel J, Klatte T, Zustin J
ROFO-FORTSCHR RONTG. 2021;193(1):80-82.

High-throughput lossy-to-lossless 3D image compression
Rossinelli D, Fourestey G, Schmidt F, Busse B, Kurtcuoglu V
IEEE T MED IMAGING. 2021;40(2):607-620.

TFEB-deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality
Sass F, Schlein C, Jaeckstein M, Pertzborn P, Schweizer M, Schinke T, Ballabio A, Scheja L, Heeren J, Fischer A
MOL METAB. 2021;47:101173.

Loss of glucocorticoid rhythm induces an osteoporotic phenotype in female mice
Schilperoort M, Kroon J, Kooijman S, Smit A, Gentenaar M, Mletzko K, Schmidt F, van Ruijven L, Busse B, Pereira A, Appelman-Dijkstra N, Bravenboer N, Rensen P, Meijer O, Winter E
AGING CELL. 2021;20(10):.

Weightbearing Computed Tomography as a Novel Imaging Modality: Assessment of Peritalar Instability
Schlickewei C, Steadman J, Stürznickel J, Krähenbühl N, Frosch K

Bone microarchitecture in patients with autoimmune hepatitis
Schmidt C, Stürznickel J, Strahl A, Oheim R, Weiler-Normann C, Sebode M, Barvencik F, Lohse A, Schinke T, Amling M, Schramm C, Rolvien T
J BONE MINER RES. 2021;36(7):1316-1325.

Prevalence of low alkaline phosphatase activity in laboratory assessment: Is hypophosphatasia an underdiagnosed disease?
Schmidt T, Schmidt C, Amling M, Kramer J, Barvencik F
ORPHANET J RARE DIS. 2021;16(1):.

Evaluation of postural stability in patients screened for osteoporosis: A retrospective study of 1086 cases
Simon A, Rupp T, Hoenig T, Vettorazzi E, Amling M, Rolvien T
GAIT POSTURE. 2021;88:304-310.

Smeets R, Henningsen A, Zernial O, Stürmer E, Fiedler I, Wolff J, Schäfer S, Vollkommer T, Gosau M, Stolzer C, Fuest S
Die zahnärztliche Praxis. 2021;2021(11/12 2020):8-16.

Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype
Soldati C, Lopez-Fabuel I, Wanderlingh L, Garcia-Macia M, Monfregola J, Esposito A, Napolitano G, Guevara-Ferrer M, Scotto Rosato A, Krogsaeter E, Paquet D, Grimm C, Montefusco S, Braulke T, Storch S, Mole S, De Matteis M, Ballabio A, Sampaio J, McKay T, Johannes L, Bolaños J, Medina D
EMBO MOL MED. 2021;13(10):.

Collagen Fiber Orientation Is Coupled with Specific Nano-Compositional Patterns in Dark and Bright Osteons Modulating Their Biomechanical Properties
Stockhausen K, Qwamizadeh M, Wölfel E, Hemmatian H, Fiedler I, Flenner S, Longo E, Amling M, Greving I, Ritchie R, Schmidt F, Busse B
ACS NANO. 2021;15(1):455-467.

Variability in stem taper surface topography affects the degree of corrosion and fretting in total hip arthroplasty
Stockhausen K, Riedel C, Belinski A, Rothe D, Gehrke T, Klebig F, Gebauer M, Amling M, Citak M, Busse B
SCI REP-UK. 2021;11(1):9348.

Safety and performance of biodegradable magnesium-based implants in children and adolescents
Stürznickel J, Delsmann M, Jungesblut O, Stücker R, Knorr C, Rolvien T, Kertai M, Rupprecht M
INJURY. 2021;52(8):2265-2271.

Compound heterozygous frameshift mutations in MESD cause a lethal syndrome suggestive of osteogenesis imperfecta type XX
Stürznickel J, Jähn-Rickert K, Zustin J, Hennig F, Delsmann M, Schoner K, Rehder H, Kreczy A, Schinke T, Amling M, Kornak U, Oheim R
J BONE MINER RES. 2021;36(6):1077-1087.

Bilateral Looser zones or pseudofractures in the anteromedial tibia as a component of medial tibial stress syndrome in athletes
Stürznickel J, Jandl N, Delsmann M, von Vopelius E, Barvencik F, Amling M, Ueblacker P, Rolvien T, Oheim R
KNEE SURG SPORT TR A. 2021;29(5):1644-1650.

Clinical Phenotype and Relevance of LRP5 and LRP6 Variants in Patients With Early-Onset Osteoporosis (EOOP)
Stürznickel J, Rolvien T, Delsmann A, Butscheidt S, Barvencik F, Mundlos S, Schinke T, Kornak U, Amling M, Oheim R
J BONE MINER RES. 2021;36(2):271-282.

Relevance of in-depth skeletal assessment by high-resolution peripheral quantitative computed tomography (HR-pQCT) in orthopedics and trauma surgery
Stürznickel J, Schmidt F
FUSS & SPRUNGGELENK. 2021;19(1):19-26.

Bone microarchitecture of the distal fibula assessed by HR-pQCT
Stürznickel J, Schmidt F, Schäfer H, Beil F, Frosch K, Schlickewei C, Amling M, Barg A, Rolvien T
BONE. 2021;151:.

Bone healing and reactivation of remodeling under asfotase alfa therapy in adult patients with pediatric-onset hypophosphatasia
Stürznickel J, Schmidt F, von Vopelius E, Delsmann M, Schmidt C, Jandl N, Oheim R, Barvencik F
BONE. 2021;143:115794.

The WNT1G177C mutation specifically affects skeletal integrity in a mouse model of osteogenesis imperfecta type XV
Vollersen N, Zhao W, Rolvien T, Lange F, Schmidt F, Sonntag S, Shmerling D, von Kroge S, Stockhausen K, Sharaf A, Schweizer M, Karsak M, Busse B, Bockamp E, Semler O, Amling M, Oheim R, Schinke T, Yorgan T
BONE RES. 2021;9(1):48.

Bone loss recovery in mice following microgravity with concurrent bone-compartment-specific osteocyte characteristics
von Kroge S, Wölfel E, Buravkova L, Atiakshin D, Markina E, Schinke T, Rolvien T, Busse B, Jähn-Rickert K
EUR CELLS MATER. 2021;42:220-231.

Skeletal characterization in a patient with Hajdu-Cheney syndrome undergoing total knee arthroplasty
von Vopelius E, Oheim R, Amling M, Rolvien T, Beil F
OSTEOPOROSIS INT. 2021;32(9):1899-1904.

Silk Fiber-Reinforced Hyaluronic Acid-Based Hydrogel for Cartilage Tissue Engineering
Weitkamp J, Wöltje M, Nußpickel B, Schmidt F, Aibibu D, Bayer A, Eglin D, Armiento A, Arnold P, Cherif C, Lucius R, Smeets R, Kurz B, Behrendt P
INT J MOL SCI. 2021;22(7):.

Transgenic inhibition of interleukin-6 trans-signaling does not prevent skeletal pathologies in mucolipidosis type II mice
Westermann L, Baranowsky A, Di Lorenzo G, Danyukova T, Soul J, Schwartz J, Hendrickx G, Amling M, Rose-John S, Garbers C, Schinke T, Pohl S
SCI REP-UK. 2021;11(1):3556.

Decreased Trabecular Bone Mass in Col22a1-Deficient Mice
Zhao W, Wiedemann P, Wölfel E, Neven M, Peters S, Imhof T, Koch M, Busse B, Amling M, Schinke T, Yorgan T
CELLS-BASEL. 2021;10(11):.

Breaking new ground in mineralized tissue: Assessing tissue quality in clinical and laboratory studies
Zimmermann E, Fiedler I, Busse B

Topographical mapping of the mechanical characteristics of the human neurocranium considering the role of individual layers
Zwirner J, Safavi S, Scholze M, Li K, Waddell J, Busse B, Ondruschka B, Hammer N
SCI REP-UK. 2021;11(1):.

Hip Morphology in Mucolipidosis Type II
Ammer L, Oussoren E, Muschol N, Pohl S, Rubio-Gozalbo M, Santer R, Stücker R, Vettorazzi E, Breyer S
J CLIN MED. 2020;9(3):E728.

The neuropeptide calcitonin gene-related peptide alpha is essential for bone healing
Appelt J, Baranowsky A, Jahn D, Yorgan T, Köhli P, Otto E, Farahani S, Graef F, Fuchs M, Herrera A, Amling M, Schinke T, Frosch K, Duda G, Tsitsilonis S, Keller J
EBIOMEDICINE. 2020;59:102970.

In Vitro Feasibility Analysis of a New Sutureless Wound-Closure System Based on a Temperature-Regulated Laser and a Transparent Collagen Membrane for Laser Tissue Soldering (LTS)
Birkelbach M, Smeets R, Fiedler I, Kluwe L, Wehner M, Trebst T, Hartjen P
INT J MOL SCI. 2020;21(19):.

Zebrafish: An Emerging Model for Orthopedic Research
Busse B, Galloway J, Gray R, Harris M, Kwon R
J ORTHOP RES. 2020;38(5):925-936.

Primary intraosseous meningioma: clinical, histological, and differential diagnostic aspects
Butscheidt S, Ernst M, Rolvien T, Hubert J, Zustin J, Amling M, Martens T
J NEUROSURG. 2020;133(2):451–461.

Warmth Prevents Bone Loss Through the Gut Microbiota
Chevalier C, Kieser S, Çolakoğlu M, Hadadi N, Brun J, Rigo D, Suárez-Zamorano N, Spiljar M, Fabbiano S, Busse B, Ivanišević J, Macpherson A, Bonnet N, Trajkovski M
CELL METAB. 2020;32(4):575-590.e7.

More Bone with Less Minerals? The Effects of Dietary Phosphorus on the Post-Cranial Skeleton in Zebrafish
Cotti S, Huysseune A, Koppe W, Rücklin M, Marone F, Wölfel E, Fiedler I, Busse B, Forlino A, Witten P
INT J MOL SCI. 2020;21(15):.

Fgfr3 Is a Positive Regulator of Osteoblast Expansion and Differentiation During Zebrafish Skull Vault Development
Dambroise E, Ktorza I, Brombin A, Abdessalem G, Edouard J, Luka M, Fiedler I, Binder O, Pelle O, Patton E, Busse B, Menager M, Sohm F, Legeai-Mallet L
J BONE MINER RES. 2020;35(9):1782-1797.

Combined in-vitro and in-silico analyses of missense mutations in GNPTAB provide new insights into the molecular bases of mucolipidosis II and III alpha/beta
Danyukova T, Ludwig N, Velho R, Harms F, Güneş N, Tidow H, Schwartz I, Tüysüz B, Pohl S
HUM MUTAT. 2020;41(1):133-139.

Development of Enthesopathies and Joint Structural Damage in a Murine Model of X-Linked Hypophosphatemia
Faraji-Bellée C, Cauliez A, Salmon B, Fogel O, Zhukouskaya V, Benoit A, Schinke T, Roux C, Linglart A, Miceli-Richard C, Chaussain C, Briot K, Bardet C
FRONT CELL DEV BIOL. 2020;8:854.

Symptomatic Intraosseous Vascular Malformation of Infraorbital Rim: A Case Report With Literature Survey
Friedrich R, Grzyska U, Kohlrusch F, VON Kroge S, Vollkommer T, Luebke A
ANTICANCER RES. 2020;40(6):3333-3343.

Ablation Precision and Thermal Effects of a Picosecond Infrared Laser (PIRL) on Roots of Human Teeth: A Pilot Study Ex Vivo
Friedrich R, Quade M, Jowett N, Kroetz P, Amling M, Kohlrusch F, Zustin J, Gosau M, SchlÜter H, Miller R
IN VIVO. 2020;34(5):2325-2336.

Targeting of δ-catenin to postsynaptic sites through interaction with the Shank3 N-terminus
Hassani Nia F, Woike D, Martens V, Klüssendorf M, Hönck H, Harder S, Kreienkamp H
MOL AUTISM. 2020;11(1):85.

WNT16 Requires Gα Subunits as Intracellular Partners for Both Its Canonical and Non-Canonical WNT Signalling Activity in Osteoblasts
Hendrickx G, Boudin E, Verbeek M, Fransen E, Mortier G, Van Hul W
CALCIFIED TISSUE INT. 2020;106(3):294-302.

Enzyme replacement therapy in mice lacking arylsulfatase B targets bone remodeling cells, but not chondrocytes
Hendrickx G, Danyukova T, Baranowsky A, Rolvien T, Angermann A, Schweizer M, Keller J, Schröder J, Meyer-Schwesinger C, Muschol N, Paganini C, Rossi A, Amling M, Pohl S, Schinke T
HUM MOL GENET. 2020;29(5):803-816.

Footstrike Patterns in Runners: Concepts, Classifications, Techniques, and Implications for Running-Related Injuries
Hoenig T, Rolvien T, Hollander K
DEUT Z SPORTMED. 2020;(No. 3):.

Adult osteosclerotic metaphyseal dysplasia with progressive osteonecrosis of the jaws and abnormal bone resorption pattern due to a LRRK1 splice site mutation
Howaldt A, Hennig A, Rolvien T, Rössler U, Stelzer N, Knaus A, Böttger S, Zustin J, Geißler S, Oheim R, Amling M, Howaldt H, Kornak U
J BONE MINER RES. 2020;35(7):1322-1332.

Cartilage calcification is associated with histological degeneration of the knee joint: a highly prevalent, age-independent systemic process
Hubert J, Beil F, Rolvien T, Butscheidt S, Hischke S, Püschel K, Frosch S, Mussawy H, Ries C, Hawellek T
OSTEOARTHR CARTILAGE. 2020;28(10):1351-1361.

Analysis of low-dose estrogen on callus BMD as measured by pQCT in postmenopausal women
Jäckle K, Kolb J, Schilling A, Schlickewei C, Amling M, Rueger J, Lehmann W
BMC MUSCULOSKEL DIS. 2020;21(1):693.

Elevated Bone Hardness Under Denosumab Treatment, With Persisting Lower Osteocyte Viability During Discontinuation
Jähn-Rickert K, Wölfel E, Jobke B, Riedel C, Hellmich M, Werner M, McDonald M, Busse B
FRONT ENDOCRINOL. 2020;11:250.

Impaired Bone Microarchitecture in Patients with Hereditary Hemochromatosis and Skeletal Complications
Jandl N, Rolvien T, Schmidt T, Mussawy H, Nielsen P, Oheim R, Amling M, Barvencik F
CALCIFIED TISSUE INT. 2020;106(5):465-475.

Total Hip Arthroplasty in Multiple Sclerosis
Jandl N, Schmidt T, Niemeier A
Z ORTHOP UNFALLCHIR. 2020;158(2):188-193.

Large osteocyte lacunae in iliac crest infantile bone are not associated with impaired mineral distribution or signs of osteocytic osteolysis
Jandl N, von Kroge S, Stürznickel J, Baranowsky A, Stockhausen K, Mushumba H, Beil F, Püschel K, Amling M, Rolvien T
BONE. 2020;135:115324.

Radiological and Histopathological Features of Internal Tooth Resorption
Koehne T, Zustin J, Amling M, Friedrich R
IN VIVO. 2020;34(4):1875-1882.

Modeling Spontaneous Bone Metastasis Formation of Solid Human Tumor Xenografts in Mice
Labitzky V, Baranowsky A, Maar H, Hanika S, Starzonek S, Ahlers A, Stübke K, Koziolek E, Heine M, Schäfer P, Windhorst S, Jücker M, Riecken K, Amling M, Schinke T, Schumacher U, Valentiner U, Lange T
CANCERS. 2020;12(2):.

Disruption of the hepcidin/ferroportin regulatory circuitry causes low axial bone mass in mice
Ledesma-Colunga M, Baschant U, Fiedler I, Busse B, Hofbauer L, Muckenthaler M, Altamura S, Rauner M
BONE. 2020;137:115400.

Phenomenon of osteocyte lacunar mineralization: indicator of former osteocyte death and a novel marker of impaired bone quality?
Milovanovic P, Busse B
ENDOCR CONNECT. 2020;9(4):R70-R80.

Hepatocyte growth factor and matrix metalloprotease 2 levels in synovial fluid of the knee joint are correlated with clinical outcome of meniscal repair
Mull C, Wohlmuth P, Krause M, Alm L, Kling H, Schilling A, Frosch K
KNEE. 2020;27(4):1143-1150.

ALCAM contributes to brain metastasis formation in non-small-cell lung cancer through interaction with the vascular endothelium
Münsterberg J, Loreth D, Brylka L, Werner S, Karbanova J, Gandrass M, Schneegans S, Besler K, Hamester F, Robador J, Bauer A, Werner Schneider S, Wrage M, Lamszus K, Matschke J, Vashist Y, Uzunoglu G, Steurer S, Horst A, Oliveira-Ferrer L, Glatzel M, Schinke T, Corbeil D, Pantel K, Maire C, Wikman H
NEURO-ONCOLOGY. 2020;22(7):955-966.

Accelerated tooth movement in Rsk2-deficient mice with impaired cementum formation
Nottmeier C, Decker M, Luther J, von Kroge S, Kahl-Nieke B, Amling M, Schinke T, Petersen J, Koehne T
INT J ORAL SCI. 2020;12(1):35.

Human Heterozygous ENPP1 Deficiency Is Associated With Early Onset Osteoporosis, a Phenotype Recapitulated in a Mouse Model of Enpp1 Deficiency
Oheim R, Zimmerman K, Maulding N, Stürznickel J, von Kroge S, Kavanagh D, Stabach P, Kornak U, Tommasini S, Horowitz M, Amling M, Thompson D, Schinke T, Busse B, Carpenter T, Braddock D
J BONE MINER RES. 2020;35(3):528-539.

Multiscale bone quality analysis in osteoarthritic knee joints reveal a role of the mechanosensory osteocyte network in osteophytes
Rabelo G, Vom Scheidt A, Klebig F, Hemmatian H, Citak M, Amling M, Busse B, Jähn K
SCI REP-UK. 2020;10(1):673.

Cellular Contributors to Bone Homeostasis
Rauner M, Jähn K, Hemmatian H, Colditz J, Goettsch C
2020. Cardiovascular Calcification and Bone Mineralization. Aikawa E, Hutcheson J (Hrsg.). Cham: Springer International Publishing, 333-371.

Age-related changes of micro-morphological subchondral bone properties in the healthy femoral head
Ries C, Boese C, Stürznickel J, Koehne T, Hubert J, Pastor M, Hahn M, Meier S, Beil F, Püschel K, Amling M, Rolvien T
OSTEOARTHR CARTILAGE. 2020;28(11):1437-1447.

Gnathodiaphyseal dysplasia is not recapitulated in a respective mouse model carrying a mutation of the Ano5 gene
Rolvien T, Avci O, von Kroge S, Koehne T, Selbert S, Sonntag S, Shmerling D, Kornak U, Oheim R, Amling M, Schinke T, Yorgan T
BONE REP. 2020;12:100281.

A novel, multi-level approach to assess allograft incorporation in revision total hip arthroplasty
Rolvien T, Friesecke C, Butscheidt S, Gehrke T, Hahn M, Püschel K
SCI REP-UK. 2020;10(1):15226.

Whole-Exome Sequencing Identifies Novel Compound Heterozygous ZNF469 Mutations in Two Siblings with Mild Brittle Cornea Syndrome
Rolvien T, Kornak U, Linke S, Amling M, Oheim R
CALCIFIED TISSUE INT. 2020;107(3):294-299.

Long-term immobilization in elderly females causes a specific pattern of cortical bone and osteocyte deterioration different from postmenopausal osteoporosis
Rolvien T, Milovanovic P, Schmidt F, von Kroge S, Wölfel E, Krause M, Wulff B, Püschel K, Ritchie R, Amling M, Busse B
J BONE MINER RES. 2020;35(7):1343-1351.

Skeletal deterioration in COL2A1-related spondyloepiphyseal dysplasia occurs prior to osteoarthritis
Rolvien T, Yorgan T, Kornak U, Hermans-Borgmeyer I, Mundlos S, Schmidt T, Niemeier A, Schinke T, Amling M, Oheim R
OSTEOARTHR CARTILAGE. 2020;28(3):334-343.

Distinct modes of balancing glomerular cell proteostasis in mucolipidosis type II and III prevent proteinuria
Sachs W, Sachs M, Krüger E, Zielinski S, Kretz O, Huber T, Baranowsky A, Westermann L, Voltolini Velho R, Floriano Ludwig N, Yorgan T, Di Lorenzo G, Kollmann K, Braulke T, Schwartz I, Schinke T, Danyukova T, Pohl S, Meyer-Schwesinger C
J AM SOC NEPHROL. 2020;31(8):1796-1814.

Effect of variations in tissue-level ductility on human vertebral strength
Sadoughi S, Vom Scheidt A, Nawathe S, Zhu S, Moini A, Keaveny T
BONE. 2020;137:115445.

Circadian disruption by shifting the light-dark cycle negatively affects bone health in mice
Schilperoort M, Bravenboer N, Lim J, Mletzko K, Busse B, van Ruijven L, Kroon J, Rensen P, Kooijman S, Winter E
FASEB J. 2020;34(1):1052-1064.

Variation in skull bone mineral density of ringed seals (Phoca hispida) from the Gulf of Bothnia and West Greenland between 1829 and 2019
Schmidt B, Sonne C, Nachtsheim D, Dietz R, Oheim R, Rolvien T, Persson S, Amling M, Siebert U
ENVIRON INT. 2020;143:105968.

A System to Determine Risk of Osteoporosis in Patients With Autoimmune Hepatitis
Schmidt T, Schmidt C, Strahl A, Mussawy H, Rolvien T, Jandl N, Casar C, Oheim R, Schinke T, Lohse A, Amling M, Schramm C, Barvencik F
CLIN GASTROENTEROL H. 2020;18(1):226-233.e3.

Multimodal X-ray imaging of nanocontainer-treated macrophages and calcium distribution in the perilacunar bone matrix
Stachnik K, Warmer M, Mohacsi I, Hennicke V, Fischer P, Meyer J, Spitzbart T, Barthelmess M, Eich J, David C, Feldmann C, Busse B, Jähn K, Schaible U, Meents A
SCI REP-UK. 2020;10(1):1784.

Crtap and p3h1 knock out zebrafish support defective collagen chaperoning as the cause of their osteogenesis imperfecta phenotype
Tonelli F, Cotti S, Leoni L, Besio R, Gioia R, Marchese L, Giorgetti S, Villani S, Gistelinck C, Wagener R, Kobbe B, Fiedler I, Larionova D, Busse B, Eyre D, Rossi A, Witten P, Forlino A
MATRIX BIOL. 2020;90:40-60.

Arylsulfatase K inactivation causes mucopolysaccharidosis due to deficient glucuronate desulfation of heparan and chondroitin sulfate
Trabszo C, Ramms B, Chopra P, Lüllmann-Rauch R, Stroobants S, Sproß J, Jeschke A, Schinke T, Boons G, Esko J, Lübke T, Dierks T
BIOCHEM J. 2020;477(17):3433-3451.

A clinical perspective on advanced developments in bone biopsy assessment in rare bone disorders
Treurniet S, Eekhoff E, Schmidt F, Micha D, Busse B, Bravenboer N

Numerical study of crack initiation and growth in human cortical bone: Effect of micro-morphology
Wang M, Li S, Scheidt A, Qwamizadeh M, Busse B, Silberschmidt V
ENG FRACT MECH. 2020;232:.

Imbalanced cellular metabolism compromises cartilage homeostasis and joint function in a mouse model of mucolipidosis type III gamma
Westermann L, Fleischhauer L, Vogel J, Jenei-Lanzl Z, Floriano Ludwig N, Schau L, Morellini F, Baranowsky A, Yorgan T, Di Lorenzo G, Schweizer M, de Souza Pinheiro B, Guarany N, Sperb-Ludwig F, Visioli F, Oliveira Silva T, Soul J, Hendrickx G, Wiegert J, Schwartz I, Clausen-Schaumann H, Zaucke F, Schinke T, Pohl S, Danyukova T
DIS MODEL MECH. 2020;13(11):.

Sklerostin des Osteozyten-von der Expression zur klinischen Anwendung
Wölfel E, Busse B, Jähn K
OSTEOLOGIE. 2020;29(1):14-20.

Individuals with type 2 diabetes mellitus show dimorphic and heterogeneous patterns of loss in femoral bone quality
Wölfel E, Jähn-Rickert K, Schmidt F, Wulff B, Mushumba H, Sroga G, Püschel K, Milovanovic P, Amling M, Campbell G, Vashishth D, Busse B
BONE. 2020;140:115556.

Mice carrying a ubiquitous R235W mutation of Wnt1 display a bone-specific phenotype
Yorgan T, Rolvien T, Stürznickel J, Vollersen N, Lange F, Zhao W, Baranowsky A, Rosenthal L, Hermans-Borgmeyer I, Sharaf A, Karsak M, David J, Oheim R, Amling M, Schinke T
J BONE MINER RES. 2020;35(9):1726-1737.

Mice lacking plastin-3 display a specific defect of cortical bone acquisition
Yorgan T, Sari H, Rolvien T, Windhorst S, Failla A, Kornak U, Oheim R, Amling M, Schinke T
BONE. 2020;130:115062.

Mice deficient in the lysosomal enzyme palmitoyl-protein thioesterase 1 (PPT1) display a complex retinal phenotype
Atiskova Y, Bartsch S, Danyukova T, Becker E, Hagel C, Storch S, Bartsch U
SCI REP-UK. 2019;9(1):14185.

Secreted factors from synovial fibroblasts immediately regulate gene expression in articular chondrocytes
Bonitz M, Schaffer C, Amling M, Poertner R, Schinke T, Jeschke A
GENE. 2019;698:1-8.

Chemokines in Physiological and Pathological Bone Remodeling
Brylka L, Schinke T
FRONT IMMUNOL. 2019;10:2182.

Microstructure, mineral and mechanical properties of teleost intermuscular bones
Fiedler I, Zeveleva S, Duarte A, Zhao X, Depalle B, Cardoso L, Jin S, Berteau J
J BIOMECH. 2019;94:59-66.

Analysis of cobalt deposition in periprosthetic bone specimens by high-resolution synchroton XRF in undecalcified histological thin sections
Hahn M, Buzanich G, Jähn K, Reinholz U, Radtke M
MATERIALIA. 2019;6:.

Deficiency of sphingosine-1-phosphate receptor 3 does not affect the skeletal phenotype of mice lacking sphingosine-1-phosphate lyase
Heckt T, Brylka L, Neven M, Amling M, Schinke T
PLOS ONE. 2019;14(7):e0219734.

Recurrent arthrocele and sterile sinus tract formation due to ceramic wear as a differential diagnosis of periprosthetic joint infection - a case report
Jandl N, Rolvien T, Gätjen D, Jonitz-Heincke A, Springer A, Krenn V, Bader R, Rüther W
ACTA ORTHOP. 2019;90(5):501-504.

Hypophosphatasie - eine klinisch und genetisch variable Erkrankung
Jandl N, Volk A, Barvencik F
MED GENET-BERLIN. 2019;2019(31):364-371.

Age-related changes in size, bone microarchitecture and volumetric bone mineral density of the mandible in the harbor seal (Phoca vitulina)
Kahle P, Rolvien T, Kierdorf H, Roos A, Siebert U, Kierdorf U
PLOS ONE. 2019;14(10):e0224480.

How can the articular surface of the tibial plateau be best exposed? A comparison of specific surgical approaches
Krause M, Krüger S, Müller G, Püschel K, Frosch K
ARCH ORTHOP TRAUM SU. 2019;139(10):1369-1377.

Evaluation of the capability of the simulated dual energy X-ray absorptiometry-based two-dimensional finite element models for predicting vertebral failure loads
Lu Y, Zhu Y, Krause M, Huber G, Li J
MED ENG PHYS. 2019;69:43-49.

Osteoid Osteoma of the Mandible - Clinical and Histological Findings
Matthies L, Rolvien T, Pakusa T, Knipfer C, Gosau M, Amling M, Friedrich R, Zustin J
ANTICANCER RES. 2019;39(1):291-296.

Bone Marrow Plasma Cells Modulate Local Myeloid-Lineage Differentiation via IL-10
Meng L, Almeida L, Clauder A, Lindemann T, Luther J, Link C, Hofmann K, Kulkarni U, Wong D, David J, Manz R
FRONT IMMUNOL. 2019;10:1183.

Inter-site Variability of the Human Osteocyte Lacunar Network: Implications for Bone Quality
Milovanovic P, Busse B
CURR OSTEOPOROS REP. 2019;17(3):105-115.

Bone microstructure is significantly altered in CRPS-affected distal tibiae as detected by HR-pQCT: a retrospective cross-sectional study
Oehler N, Rolvien T, Schmidt T, Butscheidt S, Oheim R, Barvencik F, Mussawy H
J BONE MINER METAB. 2019;37(4):741-748.

Evaluation of long-term functional donor-site morbidity after deep circumflex iliac crest artery bone flap harvest
Rendenbach C, Goehler F, Hansen L, Kohlmeier C, Amling M, Hanken H, Beck-Broichsitter B, Heiland M, Riecke B
MICROSURG. 2019;39(4):304-309.

Stress fractures in systemic lupus erythematosus after long-term MTX use successfully treated by MTX discontinuation and individualized bone-specific therapy
Rolvien T, Creutzfeldt A, Lohse A, Amling M
LUPUS. 2019;28(6):790-793.

A novel FAM20C mutation causing hypophosphatemic osteomalacia with osteosclerosis (mild Raine syndrome) in an elderly man with spontaneous osteonecrosis of the knee
Rolvien T, Kornak U, Schinke T, Amling M, Oheim R
OSTEOPOROSIS INT. 2019;30(3):685-689.

Intra-articular osteoid osteoma accompanied by extensive bone marrow edema. A clinical and micro-morphological analysis
Rolvien T, Krause M, Zustin J, Yastrebov O, Oheim R, Barvencik F, Frosch K, Amling M
J BONE ONCOL. 2019;18:100256.

Recovery of bone mineralization and quality during asfotase alfa treatment in an adult patient with infantile-onset hypophosphatasia
Rolvien T, Schmidt T, Schmidt F, von Kroge S, Busse B, Amling M, Barvencik F
BONE. 2019;127:67-74.

FGF23 and bone microarchitecture
Rupp T, Amling M, Rolvien T
OSTEOPOROSIS INT. 2019;30(11):2359.

High FGF23 levels are associated with impaired trabecular bone microarchitecture in patients with osteoporosis
Rupp T, Butscheidt S, Vettorazzi E, Oheim R, Barvencik F, Amling M, Rolvien T
OSTEOPOROSIS INT. 2019;30(8):1655-1662.

On the Origins of Fracture Toughness in Advanced Teleosts: How the Swordfish Sword's Bone Structure and Composition Allow for Slashing under Water to Kill or Stun Prey
Schmidt F, Zimmermann E, Walsh F, Plumeyer C, Schaible E, Fiedler I, Milovanovic P, Rößle M, Amling M, Blanchet C, Gludovatz B, Ritchie R, Busse B
ADV SCI. 2019;6(12):1900287.

Lysosomal proteome analysis reveals that CLN3-defective cells have multiple enzyme deficiencies associated with changes in intracellular trafficking
Schmidtke C, Tiede S, Thelen M, Käkelä R, Jabs S, Makrypidi G, Sylvester M, Schweizer M, Braren I, Brocke-Ahmadinejad N, Cotman S, Schulz A, Gieselmann V, Braulke T
J BIOL CHEM. 2019;294(24):9592-9604.

General synovitis score and immunologic synovitis score reflect clinical disease activity in patients with advanced stage rheumatoid arthritis
Schmidt T, Najm A, Mussawy H, Burghardt R, Oehler N, Krenn V, Rüther W, Niemeier A
SCI REP-UK. 2019;9(1):8448.

Outcome of Teriparatide Treatment on Fracture Healing Complications and Symptomatic Bone Marrow Edema in Four Adult Patients With Hypophosphatasia
Schmidt T, Rolvien T, Linke C, Jandl N, Oheim R, Amling M, Barvencik F
JBMR PLUS. 2019;3(8):e10215.

Th17 cell frequency is associated with low bone mass in primary sclerosing cholangitis
Schmidt T, Schwinge D, Rolvien T, Jeschke A, Schmidt C, Neven M, Butscheidt S, Kriz M, Kunzmann L, Mussawy H, Hubert J, Hawellek T, Rüther W, Oheim R, Barvencik F, Lohse A, Schramm C, Schinke T, Amling M
J HEPATOL. 2019;70(5):941-953.

Divergent off-target effects of RSK N-terminal and C-terminal kinase inhibitors in cardiac myocytes
Stathopoulou K, Schobesberger S, Bork N, Sprenger J, Perera R, Sotoud H, Geertz B, David J, Christ T, Nikolaev V, Cuello F
CELL SIGNAL. 2019;63:109362.

The lysosomal storage disorders mucolipidosis type II, type III alpha/beta and type III gamma: Update on GNPTAB and GNPTG mutations
Velho R, Harms F, Danyukova T, Ludwig N, Friez M, Cathey S, Filocamo M, Tappino B, Güneş N, Tüysüz B, Tylee K, Brammeier K, Heptinstall L, Oussoren E, van der Ploeg A, Petersen C, Alves S, Saavedra G, Schwartz I, Muschol N, Kutsche K, Pohl S
HUM MUTAT. 2019;40(7):842-864.

Subregional areal bone mineral density (aBMD) is a better predictor of heterogeneity in trabecular microstructure of vertebrae in young and aged women than subregional trabecular bone score (TBS)
Vom Scheidt A, Grisolia Seifert E, Pokrant C, Püschel K, Amling M, Busse B, Milovanovic P
BONE. 2019;122:156-165.

Bisphosphonate treatment changes regional distribution of trabecular microstructure in human lumbar vertebrae
Vom Scheidt A, Hemmatian H, Püschel K, Krause M, Amling M, Busse B
BONE. 2019;127(127):482-487.

Collagen Fibril Plasticity is altered in Individuals with Type 2 Diabetes Mellitus and non-osteoporotic Bone Mineral Density
Woelfel E, Siebels A, Ma L, vom Scheidt A, Schmidt F, Amling M, Jaehn K, Busse B, Zimmermann E, Wulff B, Mushumba H, Püschel K, Schaible E
J BONE MINER RES. 2019;34(Suppl 1):.

Osteoblast-specific expression of Panx3 is dispensable for postnatal bone remodeling
Yorgan T, Peters S, Amling M, Schinke T
BONE. 2019;127:155-163.

Binding Immunoglobulin Protein (BIP) Inhibits TNF-α-Induced Osteoclast Differentiation and Systemic Bone Loss in an Erosive Arthritis Model
Zaiss M, Hall C, McGowan N, Babb R, Devlia V, Lucas S, Meghji S, Henderson B, Bozec A, Schett G, David J, Panayi G, Grigoriadis A, Corrigall V
ACR Open Rheumatol. 2019;1(6):382-393.

Toward Engineering the Mannose 6-Phosphate Elaboration Pathway in Plants for Enzyme Replacement Therapy of Lysosomal Storage Disorders
Zeng Y, He X, Danyukova T, Pohl S, Kermode A
J CLIN MED. 2019;8(12):.

Mechanical Competence and Bone Quality Develop During Skeletal Growth
Zimmermann E, Riedel C, Schmidt F, Stockhausen K, Chushkin Y, Schaible E, Gludovatz B, Vettorazzi E, Zontone F, Püschel K, Amling M, Ritchie R, Busse B
J BONE MINER RES. 2019;34(8):1461-1472.

Lrp1 in osteoblasts controls osteoclast activity and protects against osteoporosis by limiting PDGF-RANKL signaling
Bartelt A, Behler-Janbeck F, Beil F, Koehne T, Müller B, Schmidt T, Heine M, Ochs L, Yilmaz T, Dietrich M, Tuckermann J, Amling M, Herz J, Schinke T, Heeren J, Niemeier A
BONE RES. 2018;6:4.

Correction: Vitamin-D-Stoffwechsel des Knochens
Barvencik F, Amling M
ORTHOPADE. 2018;47(1):66.

Comparison of contact radiographed and stained histological sections for osseointegration analysis of dental implants: an in vivo study
Bissinger O, Götz C, Jeschke A, Haller B, Wolff K, Kaiser P, Kolk A
OR SURG OR MED OR PA. 2018;125(1):20-26.

Mutational analysis uncovers monogenic bone disorders in women with pregnancy-associated osteoporosis: three novel mutations in LRP5, COL1A1, and COL1A2
Butscheidt S, Delsmann A, Rolvien T, Barvencik F, Al-Bughaili M, Mundlos S, Schinke T, Amling M, Kornak U, Oheim R
OSTEOPOROSIS INT. 2018;29(7):1643-1651.

Incorporation and Remodeling of Structural Allografts in Acetabular Reconstruction: Multiscale, Micro-Morphological Analysis of 13 Pelvic Explants
Butscheidt S, Moritz M, Gehrke T, Püschel K, Amling M, Hahn M, Rolvien T
J BONE JOINT SURG AM. 2018;100(16):1406-1415.

Clinical Significance of DXA and HR-pQCT in Autosomal Dominant Osteopetrosis (ADO II)
Butscheidt S, Rolvien T, Kornak U, Schmidt F, Schinke T, Amling M, Oheim R
CALCIFIED TISSUE INT. 2018;102(1):41-52.

Pulmonary cement embolism is not associated with the cause of death in a post-mortem cohort of cement-augmented interventions in the spine
Butscheidt S, Rolvien T, Ritter J, Heinemann A, Vogel H, Amling M, Püschel K
EUR SPINE J. 2018;27(10):2593-2601.

Trabecular bone microarchitecture predicts fragility fractures in postmenopausal women on denosumab treatment
Butscheidt S, Rolvien T, Vettorazzi E, Frieling I
BONE. 2018;114:246-251.

Impaired proteoglycan glycosylation, elevated TGF-β signaling, and abnormal osteoblast differentiation as the basis for bone fragility in a mouse model for gerodermia osteodysplastica
Chan W, Steiner M, Witkos T, Egerer J, Busse B, Mizumoto S, Pestka J, Zhang H, Hausser I, Khayal L, Ott C, Kolanczyk M, Willie B, Schinke T, Paganini C, Rossi A, Sugahara K, Amling M, Knaus P, Chan D, Lowe M, Mundlos S, Kornak U
PLOS GENET. 2018;14(3):e1007242.

Impaired mineral quality in dentin in X-linked hypophosphatemia
Coyac B, Falgayrac G, Penel G, Schmitt A, Schinke T, Linglart A, McKee M, Chaussain C, Bardet C
CONNECT TISSUE RES. 2018;59(Supp.1):91-96.

Lysosomal Proteome and Secretome Analysis Identifies Missorted Enzymes and Their Nondegraded Substrates in Mucolipidosis III Mouse Cells
Di Lorenzo G, Velho R, Winter D, Thelen M, Ahmadi S, Schweizer M, De Pace R, Cornils K, Yorgan T, Grüb S, Hermans-Borgmeyer I, Schinke T, Müller-Loennies S, Braulke T, Pohl S
MOL CELL PROTEOMICS. 2018;17(8):1612-1626.

Variogram-based evaluations of DXA correlate with vertebral strength, but do not enhance the prediction compared to aBMD alone
Dong X, Lu Y, Krause M, Huber G, Chevalier Y, Leng H, Maquer G
J BIOMECH. 2018;77:223-227.

Effect of short-term formaldehyde fixation on Raman spectral parameters of bone quality
Fiedler I, Casanova M, Keplinger T, Busse B, Müller R
J BIOMED OPT. 2018;23(11):116504.

Severely Impaired Bone Material Quality in Chihuahua Zebrafish Resembles Classical Dominant Human Osteogenesis Imperfecta
Fiedler I, Schmidt F, Wölfel E, Plumeyer C, Milovanovic P, Gioia R, Tonelli F, Bale H, Jähn K, Besio R, Forlino A, Busse B
J BONE MINER RES. 2018;33(8):1489-1499.

Calcium and vitamin D in bone fracture healing and post-traumatic bone turnover
Fischer V, Haffner-Luntzer M, Amling M, Ignatius A
EUR CELLS MATER. 2018;35:365-385.

Clinical and Microstructural Findings in Paget Disease of the Entire Mandible
Friedrich R, Luebke A, Amling M, Koehne T
J ORAL MAXIL SURG. 2018;76(2):336-346.

Loss of murine Gfi1 causes neutropenia and induces osteoporosis depending on the pathogen load and systemic inflammation
Geissler S, Textor M, Stumpp S, Seitz S, Lekaj A, Brunk S, Klaassen S, Schinke T, Klein C, Mundlos S, Kornak U, Kühnisch J
PLOS ONE. 2018;13(6):e0198510.

Calcification of the acetabular labrum of the hip: prevalence in the general population and relation to hip articular cartilage and fibrocartilage degeneration
Hawellek T, Hubert J, Hischke S, Krause M, Bertrand J, Schmidt B, Kronz A, Püschel K, Rüther W, Niemeier A
ARTHRITIS RES THER. 2018;20(1):104.

Conditional mouse models support the role of SLC39A14 (ZIP14) in Hyperostosis Cranialis Interna and in bone homeostasis
Hendrickx G, Borra V, Steenackers E, Yorgan T, Hermans C, Boudin E, Waterval J, Jansen I, Aydemir T, Kamerling N, Behets G, Plumeyer C, D'Haese P, Busse B, Everts V, Lammens M, Mortier G, Cousins R, Schinke T, Stokroos R, Manni J, Van Hul W
PLOS GENET. 2018;14(4):e1007321.

Labral calcification in end-stage osteoarthritis of the hip correlates with pain and clinical function
Hubert J, Hawellek T, Moe M, Hischke S, Krause M, Rolvien T, Schmidt T, Rüther W, Niemeier A
J ORTHOP RES. 2018;36(4):1248-1255.

Cartilage calcification of the ankle joint is associated with osteoarthritis in the general population
Hubert J, Weiser L, Hischke S, Uhlig A, Rolvien T, Schmidt T, Butscheidt S, Püschel K, Lehmann W, Beil F, Hawellek T
BMC MUSCULOSKEL DIS. 2018;19(1):169.

Phenotype and Viability of MLO-Y4 Cells Is Maintained by TGFβ₃ in a Serum-Dependent Manner within a 3D-Co-Culture with MG-63 Cells
Jähn K, Mason D, Ralphs J, Evans B, Archer C, Richards R, Stoddart M
INT J MOL SCI. 2018;19(7):1-11.

Perturbed bone composition and integrity with disorganized osteoblast function in zinc receptor/Gpr39-deficient mice
Jovanovic M, Schmidt F, Guterman-Ram G, Khayyeri H, Hiram-Bab S, Orenbuch A, Katchkovsky S, Aflalo A, Isaksson H, Busse B, Jähn K, Levaot N
FASEB J. 2018;32(5):2507-2518.

Gegenseitige Beeinflussung von Immunsystem und Knochen
Kamradt T, Amling M, Dankbar B, Dudeck A, Gunzer M, Ignatius A, Krönke G, Kubatzky K, Pap T, Prinz I, Schett G, Schinke T, Tuckermann J, Waisman A
Z RHEUMATOL. 2018;77(Suppl 1):8-11.

Autologous bridging of rotator cuff tears with a hamstring tendon patch. A cadaver feasibility study and biomechanical testing
Kircher J, Schmidt F, Hawellek T, Hubert J, Hedtmann A, Püschel K, Hahn M, Niemeier A
CLIN BIOMECH. 2018;56:36-39.

β-aminoisobutyric Acid, l -BAIBA, Is a Muscle-Derived Osteocyte Survival Factor
Kitase Y, Vallejo , Gutheil , Vemula H, Jähn K, Yi , Zhou , Brotto M, Bonewald L
CELL REP. 2018;22(6):1531-1544.

Histopathologische Befunde am Interface einer künstlichen Hüftpfanne mit einer 3D-Titannetz-Beschichtung nach einer Standzeit von 27 Jahren
Koch F, Koch A, Amling M, Hahn M
OSTEOLOGIE. 2018;27(03):165-171.

Inhibition of bone resorption by bisphosphonates interferes with orthodontically induced midpalatal suture expansion in mice
Koehne T, Kahl-Nieke B, Amling M, Korbmacher-Steiner H
CLIN ORAL INVEST. 2018;22(6):2345-2351.

Differences in maxillomandibular morphology among patients with mucopolysaccharidoses I, II, III, IV and VI: a retrospective MRI study
Koehne T, Köhn A, Friedrich R, Kordes U, Schinke T, Muschol N, Kahl-Nieke B
CLIN ORAL INVEST. 2018;22(3):1541-1549.

In Vivo Analysis of the Biocompatibility and Macrophage Response of a Non-Resorbable PTFE Membrane for Guided Bone Regeneration
Korzinskas T, Jung O, Smeets R, Stojanovic S, Najman S, Glenske K, Hahn M, Wenisch S, Schnettler R, Barbeck M
INT J MOL SCI. 2018;19(10):2952.

Bone microarchitecture of the tibial plateau in skeletal health and osteoporosis
Krause M, Hubert J, Deymann S, Hapfelmeier A, Wulff B, Petersik A, Püschel K, Amling M, Hawellek T, Frosch K
KNEE. 2018;25(4):559-567.

Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand
Luther J, Yorgan T, Rolvien T, Ulsamer L, Koehne T, Liao N, Keller D, Vollersen N, Teufel S, Neven M, Peters S, Schweizer M, Trumpp A, Rosigkeit S, Bockamp E, Mundlos S, Kornak U, Oheim R, Amling M, Schinke T, David J
SCI TRANSL MED. 2018;10(466):eaau7137.

Cementum as a source of DNA in challenging forensic cases
Mansour H, Krebs O, Sperhake J, Augustin C, Koehne T, Amling M, Püschel K
J FORENSIC LEG MED. 2018;54:76-81.

Bone tissue aging affects mineralization of cement lines
Milovanovic P, Vom Scheidt A, Mletzko K, Sarau G, Püschel K, Djuric M, Amling M, Christiansen S, Busse B
BONE. 2018;110:187-193.

Identification of vitamin D and other bone metabolism parameters as risk factors for primary bone marrow oedema syndrome
Oehler N, Mussawy H, Schmidt T, Rolvien T, Barvencik F
BMC MUSCULOSKEL DIS. 2018;19(1):451.

Thy-1 (CD90) promotes bone formation and protects against obesity
Picke A, Campbell G, Blüher M, Krügel U, Schmidt F, Tsourdi E, Winzer M, Rauner M, Vukicevic V, Busse B, Salbach-Hirsch J, Tuckermann J, Simon J, Anderegg U, Hofbauer L, Saalbach A
SCI TRANSL MED. 2018;10(453):eaao6806 .

Thy-1 Deficiency Augments Bone Loss in Obesity by Affecting Bone Formation and Resorption
Picke A, Campbell G, Schmidt F, Busse B, Rauner M, Simon J, Anderegg U, Hofbauer L, Saalbach A
FRONT CELL DEV BIOL. 2018;6:127.

Differential effects of high-fat diet and exercise training on bone and energy metabolism
Picke A, Sylow L, Møller L, Kjøbsted R, Schmidt F, Steejn M, Salbach-Hirsch J, Hofbauer C, Blüher M, Saalbach A, Busse B, Rauner M, Hofbauer L
BONE. 2018;116:120-134.

The Lysosomal Protein Arylsulfatase B Is a Key Enzyme Involved in Skeletal Turnover
Pohl S, Angermann A, Jeschke A, Hendrickx G, Yorgan T, Makrypidi-Fraune G, Steigert A, Kuehn S, Rolvien T, Schweizer M, Koehne T, Neven M, Winter O, Velho R, Albers J, Streichert T, Pestka J, Baldauf C, Breyer S, Stuecker R, Muschol N, Cox T, Saftig P, Paganini C, Rossi A, Amling M, Braulke T, Schinke T
J BONE MINER RES. 2018;33(12):2186-2201.

Functional donor site morbidity longer than one year after fibula free flap: A prospective biomechanical analysis
Rendenbach C, Rashad A, Hansen L, Kohlmeier C, Dyck M, Suling A, Assaf A, Amling M, Heiland M, Wikner J, Riecke B, Kreutzer K
MICROSURG. 2018;38(4):395-401.

Cellular Mechanisms Responsible for Success and Failure of Bone Substitute Materials
Rolvien T, Barbeck M, Wenisch S, Amling M, Krause M
INT J MOL SCI. 2018;19(10):2893.

Skeletal dissemination in Paget's disease of the spine
Rolvien T, Butscheidt S, Zustin J, Amling M
EUR SPINE J. 2018;27(Suppl 3):453-457.

A novel COL1A2 C-propeptide cleavage site mutation causing high bone mass osteogenesis imperfecta with a regional distribution pattern
Rolvien T, Kornak U, Stürznickel J, Schinke T, Amling M, Mundlos S, Oheim R
OSTEOPOROSIS INT. 2018;29(1):243-246.

Early bone tissue aging in human auditory ossicles is accompanied by excessive hypermineralization, osteocyte death and micropetrosis
Rolvien T, Schmidt F, Milovanovic P, Jähn K, Riedel C, Butscheidt S, Püschel K, Jeschke A, Amling M, Busse B
SCI REP-UK. 2018;8(1):1920.

Comparison of Bone Microarchitecture Between Adult Osteogenesis Imperfecta and Early-Onset Osteoporosis
Rolvien T, Stürznickel J, Schmidt F, Butscheidt S, Schmidt T, Busse B, Mundlos S, Schinke T, Kornak U, Amling M, Oheim R
CALCIFIED TISSUE INT. 2018;103(5):512-521.

Inter-site variability of the osteocyte lacunar network in the cortical bone underpins fracture susceptibility of the superolateral femoral neck
Rolvien T, Vom Scheidt A, Stockhausen K, Milovanovic P, Djonic D, Hubert J, Hawellek T, Wacker A, Jebens V, Püschel K, Zimmermann E, Djuric M, Amling M, Busse B
BONE. 2018;112:187-193.

Low physical performance determined by chair rising test muscle mechanography is associated with prevalent fragility fractures
Rupp T, Butscheidt S, Jähn K, Simon M, Mussawy H, Oheim R, Barvencik F, Amling M, Rolvien T
ARCH OSTEOPOROS. 2018;13(1):71.

Neue Einblicke in die Funktion des Knochenmarks
Schett G, Bozec A, Bekeredjian-Ding I, Chang H, David J, Dörner T, Grässel S, Gunzer M, Manz R, Mei H, Mielenz D, Müller-Ladner U, Neumann E, Radbruch A, Richter W, Straub R
Z RHEUMATOL. 2018;77(Suppl 1):4-7.

Ultra-high matrix mineralization of sperm whale auditory ossicles facilitates high sound pressure and high-frequency underwater hearing
Schmidt F, Delsmann , Mletzko K, Yorgan T, Hahn M, Siebert U, Busse B, Oheim R, Amling M, Rolvien T
P ROY SOC B-BIOL SCI. 2018;285(1893):20181820.

A retrospective analysis of bone mineral status in patients requiring spinal surgery
Schmidt T, Ebert K, Rolvien T, Oehler N, Lohmann J, Papavero L, Kothe R, Amling M, Barvencik F, Mussawy H
BMC MUSCULOSKEL DIS. 2018;19(1):53.

Disease duration and stage influence bone microstructure in patients with primary biliary cholangitis
Schmidt T, Schmidt C, Schmidt F, Butscheidt S, Mussawy H, Hubert J, Hawellek T, Oehler N, Barvencik F, Lohse A, Schinke T, Schramm C, Amling M, Rolvien T
J BONE MINER RES. 2018;33(6):1011-1019.

Is centrally induced alveolar bone loss in a large animal model preventable by peripheral hormone substitution?
Simon M, Beil F, Pogoda P, Vettorazzi E, Clarke I, Amling M, Oheim R
CLIN ORAL INVEST. 2018;22(1):495–503.

Perioperative complications after surgical treatment in degenerative adult de novo scoliosis
Simon M, Halm H, Quante M
BMC MUSCULOSKEL DIS. 2018;19(1):10.

Increased mechanical loading through controlled swimming exercise induces bone formation and mineralization in adult zebrafish
Suniaga S, Rolvien T, Vom Scheidt A, Fiedler I, Bale H, Huysseune A, Witten P, Amling M, Busse B
SCI REP-UK. 2018;8(1):3646.

Physiological and pathological osteocyte osteolysis
Tsourdi E, Jähn K, Rauner M, Busse B, Bonewald L
J MUSCULOSKEL NEURON. 2018;18(3):292-303.

Physiological and pathological osteocytic osteolysis
Tsourdi E, Jähn K, Rauner M, Busse B, Bonewald L
J MUSCULOSKEL NEURON. 2018;18(3):292-303.

High bone turnover in mice carrying a pathogenic Notch2-mutation causing Hajdu-Cheney syndrome
Vollersen N, Hermans-Borgmeyer I, Cornils K, Fehse B, Rolvien T, Triviai I, Jeschke A, Oheim R, Amling M, Schinke T, Yorgan T
J BONE MINER RES. 2018;33(1):70-83.

Individuals afflicted with Type 2 Diabetes Mellitus show lower femoral endocortical Sclerostin expression along with higher fluorescent advanced glycation endproducts
Wölfel E, Jähn-Rickert K, Milovanovic P, Sroga G, Wulff B, Mushumba H, Püschel K, Amling M, Vashishth D, Busse B
J BONE MINER RES. 2018;2019(32):.

The high bone mass phenotype of Lrp5-mutant mice is not affected by megakaryocyte depletion
Yorgan T, David J, Amling M, Schinke T
BIOCHEM BIOPH RES CO. 2018;497(2):659-666.

Morphologische Veränderungen des Knochengewebes bei Osteopetrose
Zustin J, Amling M, Crazzolara R, Butscheidt S, Schulz A, Oheim R
PATHOLOGE. 2018;39(2):164-171.

Differential effects of Calca-derived peptides in male mice with diet-induced obesity
Bartelt A, Jeschke A, Müller B, Gaziano I, Morales M, Yorgan T, Heckt T, Heine M, Gagel R, Emeson R, Amling M, Niemeier A, Heeren J, Schinke T, Keller J
PLOS ONE. 2017;12(6):e0180547.

Quantification of Bone Fatty Acid Metabolism and Its Regulation by Adipocyte Lipoprotein Lipase
Bartelt A, Koehne T, Tödter K, Reimer R, Müller B, Behler-Janbeck F, Heeren J, Scheja L, Niemeier A
INT J MOL SCI. 2017;18(6):1264.

Osteoblast-specific overexpression of complement receptor C5aR1 impairs fracture healing
Bergdolt S, Kovtun A, Hägele Y, Liedert A, Schinke T, Amling M, Huber-Lang M, Ignatius A
PLOS ONE. 2017;12(6):e0179512.

Comparative 3D micro-CT and 2D histomorphometry analysis of dental implant osseointegration in the maxilla of minipigs
Bissinger O, Probst F, Wolff K, Jeschke A, Weitz J, Deppe H, Kolk A
J CLIN PERIODONTOL. 2017;44(4):418-427.

The Lrp4R1170Q Homozygous Knock-In Mouse Recapitulates the Bone Phenotype of Sclerosteosis in Humans
Boudin E, Yorgan T, Fijalkowski I, Sonntag S, Steenackers E, Hendrickx G, Peeters S, De Maré A, Vervaet B, Verhulst A, Mortier G, D'Haese P, Schinke T, Van Hul W
J BONE MINER RES. 2017;32(8):1739-1749.

Post-weaning epiphysiolysis causes distal femur dysplasia and foreshortened hindlimbs in fetuin-A-deficient mice
Brylka L, Köppert S, Babler A, Kratz B, Denecke B, Yorgan T, Etich J, Costa I, Brachvogel B, Boor P, Schinke T, Jahnen-Dechent W
PLOS ONE. 2017;12(10):e0187030.

Multiple Pulmonary Emboli of Bone Cement after Kyphoplasty
Butscheidt S, Ritter J, Püschel K
DTSCH ARZTEBL INT. 2017;114(44):756.

Significance of DXA and HR-pQCT for the Diagnosis of Osteopetrosis (ADO II)-Establishment of a Diagnostic Threshold.
Butscheidt S, Rolvien T, Kornak U, Schmidt F, Schinke T, Amling M, Oheim R
J BONE MINER RES. 2017;32:S167-S167.

Bedeutung von Vitamin D im Sport: Reduziert ein Mangel die Leistungsfähigkeit?
Butscheidt S, Rolvien T, Ueblacker P, Amling M, Barvencik F
SPORTVERLETZ SPORTSC. 2017;31(1):37-44.

Tissue-specific mineralization defects in the periodontium of the Hyp mouse model of X-linked hypophosphatemia
Coyac B, Falgayrac G, Baroukh B, Slimani L, Sadoine J, Penel G, Biosse-Duplan M, Schinke T, Linglart A, McKee M, Chaussain C, Bardet C
BONE. 2017;103:334-346.

Calcium and vitamin-D deficiency marginally impairs fracture healing but aggravates posttraumatic bone loss in osteoporotic mice
Fischer V, Haffner-Luntzer M, Prystaz K, Scheidt A, Busse B, Schinke T, Amling M, Ignatius A
SCI REP-UK. 2017;7(1):Art. 7223.

The chaperone activity of 4PBA ameliorates the skeletal phenotype of Chihuahua, a zebrafish model for dominant osteogenesis imperfecta
Gioia R, Tonelli F, Ceppi I, Biggiogera M, Leikin S, Fisher S, Tenedini E, Yorgan T, Schinke T, Tian K, Schwartz J, Forte F, Wagener R, Villani S, Rossi A, Forlino A
HUM MOL GENET. 2017;26(15):2897-2911.

Accuracy of Bone Measurements in the Vicinity of Titanium Implants in CBCT Data Sets: A Comparison of Radiological and Histological Findings in Minipigs
Gröbe A, Semmusch J, Schöllchen M, Hanken H, Hahn M, Eichhorn W, Schön G, Jung O, Stein J, Reitmeier A, Heiland M, Smeets R, Precht C
BIOMED RES INT . 2017;2017:3848207.

Cobalt deposition in mineralized bone tissue after metal-on-metal hip resurfacing: Quantitative μ-X-ray-fluorescence analysis of implant material incorporation in periprosthetic tissue
Hahn M, Busse B, Procop M, Zustin J, Amling M, Katzer A
J BIOMED MATER RES B. 2017;105(7):1855-1862.

Microcalcification of lumbar spine intervertebral discs and facet joints is associated with cartilage degeneration, but differs in prevalence and its relation to age
Hawellek T, Hubert J, Hischke S, Rolvien T, Krause M, Püschel K, Rüther W, Niemeier A
J ORTHOP RES. 2017;35(12):2692-2699.

Association between regional heterogeneity in the mid-facial bone micro-architecture and increased fragility along Le Fort lines
Janovic A, Milovanovic P, Hahn M, Rakocevic Z, Amling M, Busse B, Dimitrijevic M, Djuric M
DENT TRAUMATOL. 2017;33(4):300-306.

Mast Cells Are Critical Regulators of Bone Fracture-Induced Inflammation and Osteoclast Formation and Activity
Kroner J, Kovtun A, Kemmler J, Messmann J, Strauss G, Seitz S, Schinke T, Amling M, Kotrba J, Froebel J, Dudeck J, Dudeck A, Ignatius A
J BONE MINER RES. 2017;32(12):2431-2444.

Loss of menin in osteoblast lineage affects osteocyte-osteoclast crosstalk causing osteoporosis
Liu P, Lee S, Knoll J, Rauch A, Ostermay S, Luther J, Malkusch N, Lerner U, Zaiss M, Neven M, Wittig R, Rauner M, David J, Bertolino P, Zhang C, Tuckermann J
CELL DEATH DIFFER. 2017;24(4):672-682.

Atypical fracture with long-term bisphosphonate therapy is associated with altered cortical composition and reduced fracture resistance
Lloyd A, Gludovatz B, Riedel C, Luengo E, Saiyed R, Marty E, Lorich D, Lane J, Ritchie R, Busse B, Donnelly E
P NATL ACAD SCI USA. 2017;114(33):8722-8727.

Bone and adipose tissue formation
Luther J, David J
Z RHEUMATOL. 2017;76(Suppl. 1):18-21.

Muscle-Bone Crosstalk: Emerging Opportunities for Novel Therapeutic Approaches to Treat Musculoskeletal Pathologies
Maurel D, Jähn K, Lara-Castillo N
BIOMEDICINES. 2017;5(4):E62.

Denosumab and surgery for the treatment of Perthes' disease in a 9-year-old boy: favorable course documented by comprehensive imaging- a case report
Meiss A, Barvencik F, Babin K, Eggers-Stroeder G
ACTA ORTHOP. 2017;88(3):354-357.

Region-dependent patterns of trabecular bone growth in the human proximal femur: A study of 3D bone microarchitecture from early postnatal to late childhood period
Milovanovic P, Djonic D, Hahn M, Amling M, Busse B, Djuric M
AM J PHYS ANTHROPOL. 2017;164(2):281-291.

The Formation of Calcified Nanospherites during Micropetrosis Represents a Unique Mineralization Mechanism in Aged Human Bone
Milovanovic P, Zimmermann E, vom Scheidt A, Hoffmann B, Sarau G, Yorgan T, Schweizer M, Amling M, Christiansen S, Busse B
SMALL. 2017;13(3):n/a-n/a.

Changes in cortical microarchitecture are independent of areal bone mineral density in patients with fragility fractures
Mussawy H, Ferrari G, Schmidt F, Schmidt T, Rolvien T, Hischke S, Rüther W, Amling M
INJURY. 2017;48(11):2461-2465.

Evaluation of bone microstructure in CRPS-affected upper limbs by HR-pQCT
Mussawy H, Schmidt T, Rolvien T, Rüther W, Amling M
Clin Cases Miner Bone Metab. 2017;14(1):54-59.

Sheep model for osteoporosis: The effects of peripheral hormone therapy on centrally induced systemic bone loss in an osteoporotic sheep model
Oheim R, Simon M, Steiner M, Vettorazzi E, Barvencik F, Ignatius A, Amling M, Clarke I, Pogoda P, Beil F
INJURY. 2017;48(4):841-848.

The incorporation of fluoride and strontium in hydroxyapatite affects the composition, structure, and mechanical properties of human cortical bone
Riedel C, Zimmermann E, Zustin J, Niecke M, Amling M, Grynpas M, Busse B
J BIOMED MATER RES A. 2017;105(2):433-442.

Knochenstoffwechsel im Alter
Rolvien T, Amling M
OP-JOURNAL. 2017;33(03):206-212.

ß-TCP bone substitutes in tibial plateau depression fractures
Rolvien T, Barvencik F, Klatte T, Busse B, Hahn M, Rueger J, Rupprecht M
KNEE. 2017;24(5):1138-1145.

Severe bone loss and multiple fractures in SCN8A-related epileptic encephalopathy
Rolvien T, Butscheidt S, Jeschke A, Neu A, Denecke J, Kubisch C, Meisler M, Püschel K, Barvencik F, Yorgan T, Oheim R, Schinke T, Amling M
BONE. 2017;103:136-143.

Vertebral bone microarchitecture and osteocyte characteristics of three toothed whale species with varying diving behaviour
Rolvien T, Hahn M, Siebert U, Püschel K, Wilke H, Busse B, Amling M, Oheim R
SCI REP-UK. 2017;7(1):1604.

A Novel ANO5 Mutation Causing Gnathodiaphyseal Dysplasia With High Bone Turnover Osteosclerosis
Rolvien T, Koehne T, Kornak U, Lehmann W, Amling M, Schinke T, Oheim R
J BONE MINER RES. 2017;32(2):277-284.

Vitamin D regulates osteocyte survival and perilacunar remodeling in human and murine bone
Rolvien T, Krause M, Jeschke A, Yorgan T, Püschel K, Schinke T, Busse B, Demay M, Amling M
BONE. 2017;103:78-87.

Denosumab in bone marrow oedema syndrome. Response to Letter to the Editor of Injury
Rolvien T, Schmidt T, Barvencik F, Amling M
INJURY. 2017;48(10):2368.

Denosumab is effective in the treatment of bone marrow oedema syndrome
Rolvien T, Schmidt T, Butscheidt S, Amling M, Barvencik F
INJURY. 2017;48(4):874-879.

Periosteal chondroma of the cuboid with secondary aneurysmal bone cyst in a setting of secondary hyperparathyroidism
Rolvien T, Zustin J, Amling M, Yastrebov O

Economic evaluation of vitamin D and calcium food fortification for fracture prevention in Germany
Sandmann A, Amling M, Barvencik F, König H, Bleibler F
PUBLIC HEALTH NUTR. 2017;20(10):1874-1883.

Defining Restrictions and Limits of Registration-Based Quantification of Geometric Deformation in Cerebral Blood Vessels
Schetelig D, Sedlacik J, Schmidt F, Fiehler J, Werner R
2017. Bildverarbeitung für die Medizin 2017. Maier-Hain K, Deserno T, Handels H, Tolxdorff T (Hrsg.). 1. Aufl. Springer, 191-196.

Cleaning Effectiveness of Airpolishing for Periimplantitis Treatment
Schmage P, Haribyan M, Amling M, Nergiz I
J DENT RES. 2017;96(A):1606.

Assessment of collagen quality associated with non-enzymatic cross-links in human bone using Fourier-transform infrared imaging
Schmidt F, Zimmermann E, Campbell G, Sroga G, Püschel K, Amling M, Tang S, Vashishth D, Busse B
BONE. 2017;97:243-251.

Clinical, radiographic and biochemical characteristics of adult hypophosphatasia
Schmidt T, Mussawy H, Rolvien T, Hawellek T, Hubert J, Rüther W, Amling M, Barvencik F
OSTEOPOROSIS INT. 2017;28(9):2653-2662.

Anterior iliopsoas impingement due to a malpositioned acetabular component - effective relief by surgical cup reorientation
Schoof B, Jakobs O, Schmidl S, Lausmann C, Fensky F, Beckmann J, Gehrke T, Gebauer M
HIP INT. 2017;27(2):128-133.

Biocompatibility and Osseointegration of Titanium Implants with a Silver-Doped Polysiloxane Coating: An In Vivo Pig Model
Smeets R, Precht C, Hahn M, Jung O, Hartjen P, Heiland M, Gröbe A, Holthaus M, Hanken H
INT J ORAL MAX IMPL. 2017;32(6):1338–1345.

Changes of the bone structure after cap resurfacing arthroplasty of the humeral head
von Engelhardt L, Hahn M, Schulz T, Peikenkamp K, Jerosch J
ORTHOP TRAUMATOL-SUR. 2017;103(4):493-498.

Application of reference point indentation for micro-mechanical surface characterization of calcium silicate based dental materials
Antonijevic D, Milovanovic P, Riedel C, Hahn M, Amling M, Busse B, Djurić M

Joint effusion as an indication of a lung disease
Beil F, Amling M, Ruether W
EUR J INTERN MED. 2016;36:e5-e6.

Rsk2 controls synovial fibroblast hyperplasia and the course of arthritis
Derer A, Böhm C, Grötsch B, Grün J, Grützkau A, Stock M, Böhm S, Sehnert B, Gaipl U, Schett G, Hueber A, David J
ANN RHEUM DIS. 2016;75(2):413-421.

Isolated syndesmotic injuries in acute ankle sprains: diagnostic significance of clinical examination and MRI
Großterlinden L, Hartel M, Yamamura J, Schoennagel B, Bürger N, Krause M, Spiro A, Hoffmann M, Lehmann W, Rueger J, Rupprecht M
KNEE SURG SPORT TR A. 2016;24(4):1180-6.

Hypochlorhydria-induced calcium malabsorption does not affect fracture healing but increases post-traumatic bone loss in the intact skeleton
Haffner-Luntzer M, Heilmann A, Heidler V, Liedert A, Schinke T, Amling M, Yorgan T, Vom Scheidt A, Ignatius A
J ORTHOP RES. 2016;34(11):1914-1921.

Antagonizing midkine accelerates fracture healing in mice by enhanced bone formation in the fracture callus
Haffner-Luntzer M, Heilmann A, Rapp A, Roessler R, Schinke T, Amling M, Ignatius A, Liedert A
BRIT J PHARMACOL. 2016;173(14):2237-49.

Inhibition of Midkine Augments Osteoporotic Fracture Healing
Haffner-Luntzer M, Kemmler J, Heidler V, Prystaz K, Schinke T, Amling M, Kovtun A, Rapp A, Ignatius A, Liedert A
PLOS ONE. 2016;11(7):e0159278.

Articular cartilage calcification of the hip and knee is highly prevalent, independent of age but associated with histological osteoarthritis: evidence for a systemic disorder
Hawellek T, Hubert J, Hischke S, Krause M, Bertrand J, Pap T, Püschel K, Ruether W, Niemeier A
OSTEOARTHR CARTILAGE. 2016;24(12):2092-2099.

Articular cartilage calcification of the humeral head is highly prevalent and associated with osteoarthritis in the general population
Hawellek T, Hubert J, Hischke S, Vettorazzi E, Wegscheider K, Bertrand J, Pap T, Krause M, Püschel K, Ruether W, Niemeier A
J ORTHOP RES. 2016;34(11):1984-1990.

Parathyroid hormone induces expression and proteolytic processing of Rankl in primary murine osteoblasts
Heckt T, Keller J, Peters S, Streichert T, Chalaris A, Rose-John S, Mell B, Joe B, Amling M, Schinke T
BONE. 2016;92:85-93.

No obvious phenotypic abnormalities in mice lacking the Pate4 gene
Heckt T, Keller J, Reusch R, Hartmann K, Krasemann S, Hermans-Borgmeyer I, Amling M, Schinke T
BIOCHEM BIOPH RES CO. 2016;469(4):1069-1074.

Multispectral MPI for real time 3D tracking of endovascular devices
Hofmann M, Salamon J, Jung C, Kaul M, vom Scheidt A, Adam G, Ittrich H, Knopp T
2016. Insights into Imaging. 265.

Hyaline cartilage calcification of the first metatarsophalangeal joint is associated with osteoarthritis but independent of age and BMI
Hubert J, Hawellek T, Hischke S, Bertrand J, Krause M, Püschel K, Ruether W, Niemeier A
BMC MUSCULOSKEL DIS. 2016;17(1):474.

Letter to the Editor, concerning: "FGF23-regulated production of fetuin-A (AHSG) in osteocytes"
Jahnen-Dechent W, Brylka L, Schinke T, McKee M
BONE. 2016;93:223-224.

The assessment of adipocere to estimate the post-mortem interval - a skeleton from the tidelands
Jopp-van Well E, Augustin C, Busse B, Fuhrmann A, Hahn M, Tsokos M, Verhoff M, Schulz F
ANTHROPOL ANZ. 2016;73(3):235-247.

Rekonstruktive Untersuchungen und Identifikationsmaßnahmen bei unbekannten Soldaten aus dem Zweiten Weltkrieg
Jopp-van Well E, Gehl A, Säring D, Amling M, Hahn M, Sperhake J, Augustin C, Krebs O, Püschel K
Arch Kriminol. 2016;237(5 und 6):153-171.

Diffusion-weighted MRI for detection of hepatic osteodystrophy in primary sclerosing cholangitis a comparison study with dual-energy X-ray absorptiometry
Keller S, Ittrich H, Schramm C, Lohse A, Amling M, Adam G, Yamamura J
JPN J RADIOL. 2016;34(10):677-683.

Rsk2, the kinase in Coffin-Lowry syndrome controls cementum formation
Koehne T, Jeschke A, Petermann F, Seitz S, Neven M, Peters S, Luther J, Schweizer M, Schinke T, Kahl-Nieke B, Amling M, David J
J DENT RES. 2016;95(7):752-760.

Mannose 6-phosphate-dependent targeting of lysosomal enzymes is required for normal craniofacial and dental development
Koehne T, Markmann S, Schweizer M, Muschol N, Friedrich R, Hagel C, Glatzel M, Kahl-Nieke B, Amling M, Schinke T, Braulke T
BBA-MOL BASIS DIS. 2016;1862(9):1570–1580.

Intra-articular osteoid osteoma in the proximal tibia and its imaging characteristics
Krause M, Oheim R, Meenen N, Frosch K, Amling M
KNEE. 2016;23(5):915-9.

Knochen- und Fettgewebebildung
Luther J, David J
Z RHEUMATOL. 2016;75(7):701-6.

Can we induce osteoporosis in animals comparable to the human situation?
Oheim R, Schinke T, Amling M, Pogoda P
INJURY. 2016;47 Suppl 1:S3-9.

Prospective biomechanical analysis of donor-site morbidity after fibula free flap
Rendenbach C, Kohlmeier C, Suling A, Assaf A, Catala-Lehnen P, Amling M, Heiland M, Riecke B
J CRANIO MAXILL SURG. 2016;44(2):155-9.

Prospective biomechanical evaluation of donor site morbidity after radial forearm free flap
Riecke B, Kohlmeier C, Assaf A, Wikner J, Drabik A, Catalá-Lehnen P, Heiland M, Rendenbach C
BRIT J ORAL MAX SURG. 2016;54(2):181-6.

Bone biology in the elderly: clinical importance for fracture treatment
Rolvien T, Amling M
INNOV SURG SCI. 2016;1(2):49-55.

Zellulärer vs. azellulärer Knochen Eine Übersicht mit Hauptaugenmerk auf Echten Knochenfischen (Teleostei)
Rolvien T, Busse B
OSTEOLOGIE. 2016;25(2):77-82.

Methodological approach for the histological comparison between rickets and child abuse.
Rolvien T, Butscheidt S, Herrmann J, Püschel K
RECHTSMEDIZIN. 2016;26(4):313-315.

How the European eel (Anguilla anguilla) loses its skeletal framework across lifetime
Rolvien T, Nagel F, Milovanovic P, Wuertz S, Marshall R, Jeschke A, Schmidt F, Hahn M, Witten P, Amling M, Busse B
P ROY SOC B-BIOL SCI. 2016;283(1841):pii: 20161550.

Intra-articular osteoid osteoma as a differential diagnosis of diffuse mono-articular joint pain
Rolvien T, Zustin J, Mussawy H, Schmidt T, Pogoda P, Ueblacker P

Magnetic Particle / Magnetic Resonance Imaging: In-Vitro MPI-Guided Real Time Catheter Tracking and 4D Angioplasty Using a Road Map and Blood Pool Tracer Approach
Salamon J, Hofmann M, Jung C, Kaul M, Werner F, Them K, Reimer R, Nielsen P, Vom Scheidt A, Adam G, Knopp T, Ittrich H
PLOS ONE. 2016;11(6):e0156899.

Assessment of changes in collagen associated with advanced glycation end-products in human bone using vibrational spectroscopy
Schmidt F, Zimmermann E, Puschel K, Amling M, Vashishth D, Tang S, Busse B
2016. Bone Abstracts. P33.

Hypophosphatasie: Was ist gesichert in der Therapie?
Schmidt T, Amling M, Barvencik F
INTERNIST. 2016;57(12):1145-1154.

Osteozyt und osteozytäre Osteolyse. Seit 50 Jahren bekannt und doch bis heute verkannt
Schulz A, Amling M
OSTEOLOGIE. 2016;25(2):57-59.

Inhibition of Osteoarthritis by Adipose-Derived Stromal Cells Overexpressing Fra-1 in Mice
Schwabe K, Garcia M, Ubieta K, Hannemann N, Herbort B, Luther J, Noël D, Jorgensen C, Casteilla L, David J, Stock M, Herrmann M, Schett G, Bozec A
ARTHRITIS RHEUMATOL. 2016;68(1):138-51.

Deterioration of teeth and alveolar bone loss due to chronic environmental high-level fluoride and low calcium exposure
Simon M, Beil T, Riedel C, Lau G, Tomsia A, Zimmermann E, Koehne T, Ueblacker P, Ruether W, Pogoda P, Ignatius A, Amling M, Oheim R
CLIN ORAL INVEST. 2016;20(9):2361-2370.

Chronic skin inflammation leads to bone loss by IL-17-mediated inhibition of Wnt signaling in osteoblasts
Uluçkan Ö, Jimenez M, Karbach S, Jeschke A, Graña O, Keller J, Busse B, Croxford A, Finzel S, Koenders M, van den Berg W, Schinke T, Amling M, Waisman A, Schett G, Wagner E
SCI TRANSL MED. 2016;8(330):330ra37.

Eigenschaften des Osteozytennetzwerks in gesundem und erkranktem Knochen
Vom Scheidt A, Busse B
OSTEOLOGIE. 2016;25(2):69-76.

Cardiac repair in guinea pigs with human engineered heart tissue from induced pluripotent stem cells
Weinberger F, Breckwoldt K, Pecha S, Kelly A, Geertz B, Starbatty J, Yorgan T, Cheng K, Lessmann K, Stolen T, Scherrer-Crosbie M, Smith G, Reichenspurner H, Hansen A, Eschenhagen T
SCI TRANSL MED. 2016;8(363):363ra148.

Immediate effects of retinoic acid on gene expression in primary murine osteoblasts
Yorgan T, Heckt T, Rendenbach C, Helmis C, Seitz S, Streichert T, Amling M, Schinke T
J BONE MINER METAB. 2016;34(2):161-70.

Die endokrine Funktion der Osteozyten
Yorgan T, Schinke T
OSTEOLOGIE. 2016;25(2):62-68.

Osteoblast-specific Notch2 inactivation causes increased trabecular bone mass at specific sites of the appendicular skeleton
Yorgan T, Vollersen N, Riedel C, Jeschke A, Peters S, Busse B, Amling M, Schinke T
BONE. 2016;87:136-46.

Intrinsic mechanical behavior of femoral cortical bone in young, osteoporotic and bisphosphonate-treated individuals in low- and high energy fracture conditions
Zimmermann E, Schaible E, Gludovatz B, Schmidt F, Riedel C, Krause M, Vettorazzi E, Acevedo C, Hahn M, Püschel K, Tang S, Amling M, Ritchie R, Busse B
SCI REP-UK. 2016;6:21072.

Alendronate treatment alters bone tissues at multiple structural levels in healthy canine cortical bone
Acevedo C, Bale H, Gludovatz B, Wat A, Tang S, Wang M, Busse B, Zimmermann E, Schaible E, Allen M, Burr D, Ritchie R
BONE. 2015;81:352-363.

Kalzium und Vitamin D im Knochenstoffwechsel: Klinische Bedeutung für die Frakturbehandlung
Amling M
UNFALLCHIRURGIE. 2015;118(12):995-9.

Knochenstoffwechsel und Frakturbehandlung
Amling M
UNFALLCHIRURGIE. 2015;118(12):994.

Kalzium und Vitamin D in der Osteologie
Amling M, Barvencik F
Z RHEUMATOL. 2015;74(5):421-32; quiz 433-4.

Addition of a Fluoride-containing Radiopacifier Improves Micromechanical and Biological Characteristics of Modified Calcium Silicate Cements
Antonijevic D, Jeschke A, Colovic B, Milovanovic P, Jevremovic D, Kisic D, Scheidt A, Hahn M, Amling M, Jokanovic V, Busse B, Djuric M
J ENDODONT. 2015;41(12):2050-2057.

Microstructure and wettability of root canal dentine and root canal filling materials after different chemical irrigation
Antonijevic D, Milovanovic P, Brajkovic D, Ilic D, Hahn M, Amling M, Rakocevic Z, Djuric M, Busse B
APPL SURF SCI. 2015;355:369-378.

Force-sensitive autoinhibition of the von Willebrand factor is mediated by interdomain interactions
Aponte-Santamaria C, Huck V, Posch S, Bronowska A, Grässle S, Brehm M, Obser T, Schneppenheim R, Hinterdorfer P, Schneider S, Baldauf C, Grater F
BIOPHYS J. 2015;108(9):2312-21.

The Protein Tyrosine Phosphatase Rptpζ Suppresses Osteosarcoma Development in Trp53-Heterozygous Mice
Baldauf C, Jeschke A, Kanbach V, Catala-Lehnen P, Baumhoer D, Gerull H, Buhs S, Amling M, Nollau P, Harroch S, Schinke T
PLOS ONE. 2015;10(9):e0137745.

Medikamente und Knochenstoffwechsel: Klinische Bedeutung für die Frakturbehandlung
Barvencik F
UNFALLCHIRURGIE. 2015;118(12):1017-24.

Vitamin-D-Stoffwechsel des Knochens
Barvencik F, Amling M
ORTHOPADE. 2015;44(9):686-94.

3D-tracking the regenerative potential of the mandible with micro-CTs
Beck-Broichsitter B, Garling A, Koehne T, Barvencik F, Smeets R, Mehl C, Jeschke A, Wiltfang J, Becker S
ORAL MAXILLOFAC SURG. 2015;19(1):29-35.

Bone microarchitecture at muscle attachment sites: The relationship between macroscopic scores of entheses and their cortical and trabecular microstructural design
Djukic K, Milovanovic P, Hahn M, Busse B, Amling M, Djuric M
AM J PHYS ANTHROPOL. 2015;157(1):81-93.

Cutaneous na(+) storage strengthens the antimicrobial barrier function of the skin and boosts macrophage-driven host defense
Jantsch J, Schatz V, Friedrich D, Schröder A, Kopp C, Siegert I, Maronna A, Wendelborn D, Linz P, Binger K, Gebhardt M, Heinig M, Neubert P, Fischer F, Teufel S, David J, Neufert C, Cavallaro A, Rakova N, Küper C, Beck F, Neuhofer W, Muller D, Schuler G, Uder M, Bogdan C, Luft F, Titze J
CELL METAB. 2015;21(3):493-501.

Deficiency of Thrombospondin-4 in Mice Does Not Affect Skeletal Growth or Bone Mass Acquisition, but Causes a Transient Reduction of Articular Cartilage Thickness
Jeschke A, Bonitz M, Simon M, Peters S, Baum W, Schett G, Ruether W, Niemeier A, Schinke T, Amling M
PLOS ONE. 2015;10(12):e0144272.

Sharpin Controls Osteogenic Differentiation of Mesenchymal Bone Marrow Cells
Jeschke A, Catala-Lehnen P, Sieber S, Bickert T, Schweizer M, Koehne T, Wintges K, Marshall R, Mautner A, Duchstein L, Otto B, Horst A, Amling M, Kreienkamp H, Schinke T
J IMMUNOL. 2015;195(8):3675-84.

Flugzeugabstürze - Späte Bergung von Piloten aus dem Zweiten Weltkrieg in Norddeutschland
Jopp-van Well E, Gehl A, Säring D, Amling M, Hahn M, Kettner A, Bauerochse A, Haßmann H, Sperhake J, Püschel K
Berichte zur Denkmalpflege in Niedersachsen. 2015;4:188-195.

The Singh Index does not correlate with bone mineral density (BMD) measured with dual energy X-ray absorptiometry (DXA) or peripheral quantitative computed tomography (pQCT)
Klatte T, Vettorazzi E, Beckmann J, Püschel K, Amling M, Gebauer M
ARCH ORTHOP TRAUM SU. 2015;135(5):645-50.

Die Reaktion des Femurknochens auf den Oktaederquerschnitt der Revitan-Revisionsprothese: Histologische Befunde an einem Femur-Revitan-Explantat vier Monate postoperativ
Koch F, Hahn M, Fink B, Amling M
OSTEOLOGIE. 2015;24(2):120-124.

Calcium gluconate supplementation is effective to balance calcium homeostasis in patients with gastrectomy
Krause M, Keller J, Beil B, van Driel I, Zustin J, Barvencik F, Schinke T, Amling M
OSTEOPOROSIS INT. 2015;26(3):987-95.

Intact Bone Vitality and Increased Accumulation of Nonmineralized Bone Matrix in Biopsy Specimens of Juvenile Osteochondritis Dissecans: A Histological Analysis
Krause M, Lehmann D, Amling M, Rolvien T, Frosch K, Püschel K, Bohndorf K, Meenen N
AM J SPORT MED. 2015;43(6):1337-1347.

Impaired bone remodeling and its correction by combination therapy in a mouse model of mucopolysaccharidosis-I
Kühn S, Koehne T, Cornils K, Markmann S, Riedel C, Pestka J, Schweizer M, Baldauf C, Yorgan T, Krause M, Keller J, Neven M, Breyer S, Stücker R, Muschol N, Busse B, Braulke T, Fehse B, Amling M, Schinke T
HUM MOL GENET. 2015;24(24):7075-7086.

The role of patient-mode high-resolution peripheral quantitative computed tomography indices in the prediction of failure strength of the elderly women's thoracic vertebral body
Lu Y, Krause M, Bishop N, Sellenschloh K, Glüer C, Püschel K, Amling M, Morlock M, Huber G
OSTEOPOROSIS INT. 2015;26(1):237-44.

Repressing the repressor: Fra1 controls plasma cell generation
Mielenz D, Grötsch B, David J
ONCOTARGET. 2015;6(20):17861-2.

Age- and Sex-Specific Bone Structure Patterns Portend Bone Fragility in Radii and Tibiae in Relation to Osteodensitometry: A High-Resolution Peripheral Quantitative Computed Tomography Study in 385 Individuals
Milovanovic P, Adamu U, Simon M, Rolvien T, Djuric M, Amling M, Busse B
J GERONTOL A-BIOL. 2015;70(10):1269-75.

Multi-level characterization of human femoral cortices and their underlying osteocyte network reveal trends in quality of young, aged, osteoporotic and antiresorptive-treated bone
Milovanovic P, Zimmermann E, Riedel C, Scheidt A, Herzog L, Krause M, Djonic D, Djuric M, Püschel K, Amling M, Ritchie R, Busse B
BIOMATERIALS. 2015;45:46-55.

Osteopathien und Knochenstoffwechselerkrankungen: Klinische Bedeutung für die Frakturbehandlung
Oheim R
UNFALLCHIRURGIE. 2015;118(12):1007-16.

Acceptance of vitamin D-fortified products in Germany – A representative consumer survey
Sandmann A, Brown J, Mau G, Saur M, Amling M, Barvencik F
FOOD QUAL PREFER. 2015;43:53-62.

Transseptal and transmitral Parachute® implantation in conjunction with "MitraClipping"
Schaefer U, Lubos E, Deuschl F, Schofer N, Grahn H, Conradi L, Schirmer J, Reichenspurner H, Schmidt T, Frerker C, Kuck K, Westermann D, Blankenberg S, Treede H
EUROINTERVENTION. 2015;11(6):673-681.

Contribution of human papilloma virus to the incidence of squamous cell carcinoma of the head and neck in a European population with high smoking prevalence
Tinhofer I, Jöhrens K, Keilholz U, Kaufmann A, Lehmann A, Weichert W, Stenzinger A, Stromberger C, Klinghammer K, Becker E, Dommerich S, Stölzel K, Hofmann V, Hildebrandt B, Moser P, Ervens J, Böttcher A, Albers A, Stabenow R, Reinecke A, Budach V, Hoffmeister B, Raguse J
EUR J CANCER. 2015;51(4):514-21.

Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1
Vettorazzi S, Bode C, Dejager L, Frappart L, Shelest E, Klaßen C, Tasdogan A, Reichardt H, Libert C, Schneider M, Weih F, Henriette Uhlenhaut N, David J, Gräler M, Kleiman A, Tuckermann J
NAT COMMUN. 2015;6:7796.

The impact of low-magnitude high-frequency vibration on fracture healing is profoundly influenced by the oestrogen status in mice
Wehrle E, Liedert A, Heilmann A, Wehner T, Bindl R, Fischer L, Haffner-Luntzer M, Jakob F, Schinke T, Amling M, Ignatius A
DIS MODEL MECH. 2015;8(1):93-104.

Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic Effects
Wellbrock J, Latuske E, Köhler J, Wagner K, Stamm H, Vettorazzi E, Vohwinkel G, Klokow M, Uibeleisen R, Ehm P, Riecken K, Loges S, Thol F, Schubert C, Amling M, Jücker M, Bokemeyer C, Heuser M, Krauter J, Fiedler W

The Anti-Osteoanabolic Function of Sclerostin is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5
Yorgan T, Peters S, Jeschke A, Benisch P, Jakob F, Amling M, Schinke T
J BONE MINER RES. 2015;30(7):1175-1183.

The fracture mechanics of human bone: influence of disease and treatment
Zimmermann E, Busse B, Ritchie R
Bonekey Rep. 2015;4:743.

Modifications to nano- and microstructural quality and the effects on mechanical integrity in Paget's disease of bone
Zimmermann E, Köhne T, Bale H, Panganiban B, Gludovatz B, Zustin J, Hahn M, Amling M, Ritchie R, Busse B
J BONE MINER RES. 2015;30(2):264-73.

Bone as a Structural Material
Zimmermann E, Ritchie R
ADV HEALTHC MATER. 2015;4(9):1287-304.

Hepatic lipase is expressed by osteoblasts and modulates bone remodeling in obesity
Bartelt A, Beil T, Müller B, Koehne T, Yorgan T, Heine M, Yilmaz T, Ruether W, Heeren J, Schinke T, Niemeier A
BONE. 2014;62:90-98.

CLCN7 and TCIRG1 mutations differentially affect bone matrix mineralization in osteopetrotic individuals
Barvencik F, Kurth I, Koehne T, Stauber T, Zustin J, Tsiakas K, Ludwig C, Beil F, Pestka J, Hahn M, Santer R, Supanchart C, Kornak U, Del Fattore A, Jentsch T, Teti A, Schulz A, Schinke T, Amling M
J BONE MINER RES. 2014;29(4):982-91.

Differential roles of MAPK kinases MKK3 and MKK6 in osteoclastogenesis and bone loss
Boyle D, Hammaker D, Edgar M, Zaiss M, Teufel S, David J, Schett G, Firestein G
PLOS ONE. 2014;9(1):e84818.

T cell costimulation molecules CD80/86 inhibit osteoclast differentiation by inducing the IDO/tryptophan pathway
Bozec A, Zaiss M, Kagwiria R, Voll R, Rauh M, Chen Z, Mueller-Schmucker S, Kroczek R, Heinzerling L, Moser M, Mellor A, David J, Schett G
SCI TRANSL MED. 2014;6(235):235ra60.

(68)Ga DOTA-TATE PET/CT allows tumor localization in patients with tumor-induced osteomalacia but negative (111)In-octreotide SPECT/CT
Breer S, Brunkhorst T, Beil T, Peldschus K, Heiland M, Klutmann S, Barvencik F, Zustin J, Gratz K, Amling M
BONE. 2014;64:222-7.

Altered lacunar and vascular porosity in osteogenesis imperfecta mouse bone as revealed by synchrotron tomography contributes to bone fragility
Carriero A, Doube M, Vogt M, Busse B, Zustin J, Levchuk A, Schneider P, Müller R, Shefelbine S
BONE. 2014;61:116-24.

DXA and pQCT predict pertrochanteric and not femoral neck fracture load in a human side-impact fracture model
Gebauer M, Stark O, Vettorazzi E, Grifka J, Püschel K, Amling M, Beckmann J
J ORTHOP RES. 2014;32(1):31-8.

The AP-1 transcription factor Fra1 inhibits follicular B cell differentiation into plasma cells
Grötsch B, Brachs S, Lang C, Luther J, Derer A, Schlötzer-Schrehardt U, Bozec A, Fillatreau S, Berberich I, Hobeika E, Reth M, Wagner E, Schett G, Mielenz D, David J
J EXP MED. 2014;211(11):2199-2212.

The non-interventional BonViva Intravenous Versus Alendronate (VIVA) study: real-world adherence and persistence to medication, efficacy, and safety, in patients with postmenopausal osteoporosis
Hadji P, Felsenberg D, Amling M, Hofbauer L, Kandenwein J, Kurth A
OSTEOPOROSIS INT. 2014;25(1):339-347.

Midkine-deficiency delays chondrogenesis during the early phase of fracture healing in mice
Haffner-Luntzer M, Heilmann A, Rapp A, Beie S, Schinke T, Amling M, Ignatius A, Liedert A
PLOS ONE. 2014;9(12):e116282.

Increased Osteoclastogenesis in Mice Lacking the Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1
Heckt T, Bickert T, Jeschke A, Seitz S, Schulze J, Ito W, Zimmermann W, Amling M, Schinke T, Horst A, Keller J
PLOS ONE. 2014;9(12):e114360.

Microstructural properties of the mid-facial bones in relation to the distribution of occlusal loading
Janovic A, Milovanovic P, Saveljic I, Nikolic D, Hahn M, Rakocevic Z, Filipovic N, Amling M, Busse B, Djuric M
BONE. 2014;68:108-14.

Bisphosphonate-osteoclasts: changes in osteoclast morphology and function induced by antiresorptive nitrogen-containing bisphosphonate treatment in osteoporosis patients
Jobke B, Milovanovic P, Amling M, Busse B
BONE. 2014;59:37-43.

Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts
Keller J, Catala-Lehnen P, Hübner A, Jeschke A, Heckt T, Lueth A, Krause M, Koehne T, Albers J, Schulze J, Schilling S, Haberland M, Denninger H, Neven M, Hermans-Borgmeyer I, Streichert T, Breer S, Barvencik F, Levkau B, Rathkolb B, Wolf E, Calzada-Wack J, Neff F, Gailus-Durner V, Fuchs H, de Angelis M, Klutmann S, Tsourdi E, Hofbauer L, Kleuser B, Chun J, Schinke T, Amling M
NAT COMMUN. 2014;5:5215.

Trends in trabecular architecture and bone mineral density distribution in 152 individuals aged 30-90 years
Koehne T, Vettorazzi E, Küsters N, Lüneburg R, Kahl-Nieke B, Püschel K, Amling M, Busse B
BONE. 2014.

Sensory neuropathy with bone destruction due to a mutation in the membrane-shaping atlastin GTPase 3
Kornak U, Mademan I, Schinke M, Voigt M, Krawitz P, Hecht J, Barvencik F, Schinke T, Gießelmann S, Beil F, Pou-Serradell A, Vílchez J, Beetz C, Deconinck T, Timmerman V, Kaether C, De Jonghe P, Hübner C, Gal A, Amling M, Mundlos S, Baets J, Kurth I
BRAIN. 2014;137(3):683-92.

Formetric rasterstereography: a new perspective. Reply to Padulo and Ardigó
Krause M, Amling M, Barvencik F
OSTEOPOROSIS INT. 2014;25(5):1653-1654.

Vitamin D deficiency intensifies deterioration of risk factors, such as male sex and absence of vision, leading to increased postural body sway
Krause M, Anschütz W, Vettorazzi E, Breer S, Amling M, Barvencik F
GAIT POSTURE. 2014;39(1):166-171.

Radiation-free spinometry adds to the predictive power of historical height loss in clinical vertebral fracture assessment
Krause M, Lehmann A, Vettorazzi E, Amling M, Barvencik F
OSTEOPOROSIS INT. 2014;25(11):2657-62.

Accuracy of trabecular structure by HR-pQCT compared to gold standard μCT in the radius and tibia of patients with osteoporosis and long-term bisphosphonate therapy
Krause M, Museyko O, Breer S, Wulff B, Duckstein C, Vettorazzi E, Glueer C, Püschel K, Engelke K, Amling M
OSTEOPOROSIS INT. 2014;25(5):1595-606.

Metaphyseal bone formation induced by a new injectable β-TCP-based bone Substitute: a controlled study in rabbits
Krause M, Oheim R, Catala-Lehnen P, Pestka J, Hoffmann C, Huebner W, Peters F, Barvencik F, Amling M
J BIOMATER APPL. 2014;28(6):859-868.

Effects of long-term alendronate treatment on bone mineralisation, resorption parameters and biomechanics of single human vertebral trabeculae
Krause M, Soltau M, Zimmermann E, Hahn M, Kornet J, Hapfelmeier A, Breer S, Morlock M, Wulff B, Püschel K, Glueer C, Amling M, Busse B
EUR CELLS MATER. 2014;28:152-165.

Osteoblast-specific Krm2 overexpression and Lrp5 deficiency have different effects on fracture healing in mice
Liedert A, Röntgen V, Schinke T, Benisch P, Ebert R, Jakob F, Klein-Hitpass L, Lennerz J, Amling M, Ignatius A
PLOS ONE. 2014;9(7):e103250.

The role of midkine in skeletal remodelling
Liedert A, Schinke T, Ignatius A, Amling M
BRIT J PHARMACOL. 2014;171(4):870-878.

Interaktion zwischen Knochen, Fett und Insulin
Luther J, David J
Z RHEUMATOL. 2014;73(3):265-268.

Nano-structural, compositional and micro-architectural signs of cortical bone fragility at the superolateral femoral neck in elderly hip fracture patients vs. healthy aged controls
Milovanovic P, Rakocevic Z, Djonic D, Zivkovic V, Hahn M, Nikolic S, Amling M, Busse B, Djuric M
EXP GERONTOL. 2014;55:19-28.

A low-radiation exposure protocol for 3D QCT of the spine
Museyko O, Heinemann A, Krause M, Wulff B, Amling M, Püschel K, Glüer C, Kalender W, Engelke K
OSTEOPOROSIS INT. 2014;25(3):983-92.

Mandibular bone loss in ewe induced by hypothalamic-pituitary disconnection
Oheim R, Beil F, Krause M, Bindl R, Ignatius A, Pogoda P
CLIN ORAL IMPLAN RES. 2014;25(11):1239-1244.

Molecular changes in pre-metastatic lymph nodes of esophageal cancer patients
Otto B, Koenig A, Tolstonog G, Jeschke A, Klätschke K, Vashist Y, Wicklein D, Wagener C, Izbicki J, Streichert T
PLOS ONE. 2014;9(7):e102552.

Effects of extracellular phosphate on gene expression in murine osteoblasts
Rendenbach C, Yorgan T, Heckt T, Otto B, Baldauf C, Jeschke A, Streichert T, David J, Amling M, Schinke T
CALCIFIED TISSUE INT. 2014;94(5):474-83.

Denosumab mimics the natural decoy receptor osteoprotegerin by interacting with its major binding site on RANKL
Schieferdecker A, Voigt M, Riecken K, Braig F, Schinke T, Loges S, Bokemeyer C, Fehse B, Binder M
ONCOTARGET. 2014;5(16):6647-53.

Proximal femoral reconstruction after aseptic loosening following proximal femoral replacement for Ewing sarcoma: a case report with one-year follow-up
Schoof B, Jakobs O, Gehrke T, Gebauer M
HIP INT. 2014;24(1):103-7.

Massive accumulation of osteoclastic giant cells in rapid destructive hip disease
Seitz S, Zustin J, Amling M, Ruether W, Niemeier A
J ORTHOP RES. 2014;32(5):702-8.

Intravenous bisphosphonates and vitamin D in the treatment of bone marrow oedema in professional athletes
Simon M, Barvencik F, Luttke M, Amling M, Mueller-Wohlfahrt H, Ueblacker P
INJURY. 2014;45(6):981-987.

High fluoride and low calcium levels in drinking water is associated with low bone mass, reduced bone quality and fragility fractures in sheep
Simon M, Beil F, Ruther W, Busse B, Koehne T, Steiner M, Pogoda P, Ignatius A, Amling M, Oheim R
OSTEOPOROSIS INT. 2014;25(7):1891-1903.

Incidence, histopathologic analysis and distribution of tumours of the hand
Simon M, Pogoda P, Hövelborn F, Krause M, Zustin J, Amling M, Barvencik F
BMC MUSCULOSKEL DIS. 2014;15(1):182.

Fracture prevention by prophylactic femoroplasty of the proximal femur - metallic compared to cemented augmentation
Springorum R, Gebauer M, Mehrl A, Stark O, Craiovan B, Püschel K, Amling M, Grifka J, Beckmann J
J ORTHOP TRAUMA. 2014;28(7):403-409.

Inhibition of bone remodeling in young mice by bisphosphonate displaces the plasma cell niche into the spleen
Teufel S, Grötsch B, Luther J, Derer A, Schinke T, Amling M, Schett G, Mielenz D, David J
J IMMUNOL. 2014;193(1):223-233.

Relevance of Wnt signaling for osteoanabolic therapy
Yorgan T, Schinke T
Mol Cell Ther. 2014;2(1):22.

Fracture resistance of human cortical bone across multiple length-scales at physiological strain rates
Zimmermann E, Gludovatz B, Schaible E, Busse B, Ritchie R
BIOMATERIALS. 2014;35(21):5472-5481.

Canonical Wnt signaling inhibits osteoclastogenesis independent of osteoprotegerin
Albers J, Keller J, Baranowsky A, Beil F, Catala-Lehnen P, Schulze J, Amling M, Schinke T
J CELL BIOL. 2013;200(4):537-49.

Mandibular cortical shape index in non-standardised panoramic radiographs for identifying patients with osteoporosis as defined by the German Osteology Organization
Al-Dam A, Blake F, Atac A, Amling M, Blessmann M, Assaf A, Hanken H, Smeets R, Heiland M
J CRANIO MAXILL SURG. 2013;41(7):e165-9.

Micro-morphological properties of osteons reveal changes in cortical bone stability during aging, osteoporosis, and bisphosphonate treatment in women
Bernhard A, Milovanovic P, Zimmermann E, Hahn M, Djonic D, Krause M, Breer S, Püschel K, Djuric M, Amling M, Busse B
OSTEOPOROSIS INT. 2013;24(10):2671-80.

Metaphyseal fracture healing in a sheep model of low turnover osteoporosis induced by hypothalamic-pituitary disconnection (HPD)
Bindl R, Oheim R, Pogoda P, Beil F, Gruchenberg K, Reitmaier S, Wehner T, Calcia E, Radermacher P, Claes L, Amling M, Ignatius A
J ORTHOP RES. 2013;31(11):1851-7.

Osteoblast-specific expression of Fra-2/AP-1 controls adiponectin and osteocalcin expression and affects metabolism
Bozec A, Bakiri L, Jimenez M, Rosen E, Catalá-Lehnen P, Schinke T, Schett G, Amling M, Wagner E
J CELL SCI. 2013;126(Pt 23):5432-40.

Spontaneous osteonecrosis of the knee (SONK).
Breer S, Oheim R, Krause M, Marshall R, Amling M, Barvencik F
KNEE SURG SPORT TR A. 2013;21(2):340-345.

New perspectives on vitamin D sources in Germany based on a novel mathematical bottom-up model of 25(OH)D serum concentrations.
Brown J, Ignatius A, Amling M, Barvencik F
EUR J NUTR. 2013;52(7):1733-42.

New perspectives on vitamin D food fortification based on a modeling of 25(OH)D concentrations
Brown J, Sandmann A, Ignatius A, Amling M, Barvencik F
NUTR J. 2013;12(1):151.

Vitamin D deficiency induces early signs of aging in human bone, increasing the risk of fracture
Busse B, Bale H, Zimmermann E, Panganiban B, Barth H, Carriero A, Vettorazzi E, Zustin J, Hahn M, Ager J, Püschel K, Amling M, Ritchie R
SCI TRANSL MED. 2013;5(193):193ra88.

Intrapelvic dislocation of a femoral trial head during primary total hip arthroplasty requiring laparotomy for retrieval
Citak M, Klatte T, Zahar A, Day K, Kendoff D, Gehrke T, Dörner A, Gebauer M
The open orthopaedics journal. 2013;7:169-71.

Human apolipoprotein E isoforms differentially affect bone mass and turnover in vivo.
Dieckmann M, Beil F, Müller B, Bartelt A, Marshall R, Köhne T, Amling M, Ruether W, Cooper J, Humphries S, Herz J, Niemeier A
J BONE MINER RES. 2013;28(2):236-245.

Issues in interstudy comparisons of bone microarchitecture
Djuric M, Milovanovic P, Djonic D, Hahn M, Marshall R, Amling M
INT ORTHOP. 2013;37(10):2091-2.

Enhanced trabecular micro-architecture of the femoral neck in hip osteoarthritis vs. healthy controls: a micro-computer tomography study in postmenopausal women
Djuric M, Zagorac S, Milovanovic P, Djonic D, Nikolic S, Hahn M, Zivkovic V, Bumbasirevic M, Amling M, Marshall R
INT ORTHOP. 2013;37(1):21-26.

Complement C3 and C5 deficiency affects fracture healing
Ehrnthaller C, Huber-Lang M, Nilsson P, Bindl R, Redeker S, Recknagel S, Rapp A, Mollnes T, Amling M, Gebhard F, Ignatius A
PLOS ONE. 2013;8(11):e81341.

New horizons for the in vivo assessment of Major aspects of bone Quality. Microstructure and material properties assessed by Quantitative Computed Tomography and Quantitative Ultrasound methods developed by the BioAsset consortium
Glüer C, Krause M, Museyko O, Wulff B, Campbell G, Damm T, Daugschies M, Huber G, Lu Y, Pena J, Waldhausen S, Bastgen J, Rohde K, Breer S, Steinebach I, Thomsen F, Amling M, Barkmann R, Engelke K, Morlock M, Pfeilschifter J, Püschel K
OSTEOLOGIE. 2013;3:223-233.

Osteointegration humaner Allografts.
Hahn M, Moritz M, Friesecke C, Amling M, Püschel K
2013. Tissue donor recruitment and long-term outcome following tissue transplantation.. Wulff B, Püschel K, Braun C, de By T, Hetzer R (Hrsg.). 1. Aufl. Hamburg: Verlag Dr. Kovač, 69-72.

Osteocalcin is associated with testosterone in the general population and selected patients with bone disorders
Hannemann A, Breer S, Wallaschofski H, Nauck M, Baumeister S, Barvencik F, Amling M, Schinke T, Haring R, Keller J
ANDROLOGY-US. 2013;1(3):469-74.

Systemic treatment with the sphingosine-1-phosphate analog FTY720 does not improve fracture healing in mice
Heilmann A, Schinke T, Bindl R, Wehner T, Rapp A, Haffner-Luntzer M, Liedert A, Amling M, Ignatius A
J ORTHOP RES. 2013;31(11):1845-50.

The Wnt serpentine receptor Frizzled-9 regulates new bone formation in fracture healing
Heilmann A, Schinke T, Bindl R, Wehner T, Rapp A, Haffner-Luntzer M, Nemitz C, Liedert A, Amling M, Ignatius A
PLOS ONE. 2013;8(12):e84232.

10-year results following impaction bone grafting of major bone defects in 29 rotational and hinged knee revision arthroplasties: a follow-up of a previous report
Hilgen V, Citak M, Vettorazzi E, Haasper C, Day K, Amling M, Gehrke T, Gebauer M
ACTA ORTHOP. 2013;84(4):387-91.

The role of the gastrointestinal tract in calcium homeostasis and bone remodeling
Keller J, Schinke T
OSTEOPOROSIS INT. 2013;24(11):2737-48.

Mutations in WNT1 cause different forms of bone fragility
Keupp K, Beleggia F, Kayserili H, Barnes A, Steiner M, Semler O, Fischer B, Yigit G, Janda C, Becker J, Breer S, Altunoglu U, Grünhagen J, Krawitz P, Hecht J, Schinke T, Makareeva E, Lausch E, Cankaya T, Caparrós-Martín J, Lapunzina P, Temtamy S, Aglan M, Zabel B, Eysel P, Koerber F, Leikin S, Garcia K, Netzer C, Schönau E, Ruiz-Perez V, Mundlos S, Amling M, Kornak U, Marini J, Wollnik B
AM J HUM GENET. 2013;92(4):565-74.

Osteopetrosis, osteopetrorickets and hypophosphatemic rickets differentially affect dentin and enamel mineralization.
Koehne T, Marshall R, Jeschke A, Kahl-Nieke B, Schinke T, Amling M
BONE. 2013;53(1):25-33.

Calcium homeostasis influences radiological fracture healing in postmenopausal women
Kolb J, Schilling A, Bischoff J, Novo de Oliveira A, Spiro A, Hoffmann M, Amling M, Rueger J, Lehmann W
ARCH ORTHOP TRAUM SU. 2013;133(2):187-92.

Decreased bone formation and increased osteoclastogenesis cause bone loss in mucolipidosis II
Kollmann K, Pestka J, Kühn S, Schöne E, Schweizer M, Karkmann K, Otomo T, Catala-Lehnen P, Failla A, Marshall R, Krause M, Santer R, Amling M, Braulke T, Schinke T
EMBO MOL MED. 2013;5(12):1871-86.

Laboratory evaluation of toothbrush/toothpaste abrasion resistance after smooth enamel surface sealing
Korbmacher-Steiner H, Schilling A, Huck L, Kahl-Nieke B, Amling M
CLIN ORAL INVEST. 2013;17(3):765-74.

Influence of non-traumatic thoracic and lumbar vertebral fractures on sagittal spine alignment assessed by radiation-free spinometry.
Krause M, Breer S, Mohrmann B, Vettorazzi E, Marshall R, Amling M, Barvencik F
OSTEOPOROSIS INT. 2013;24(6):1859-1868.

Healing predictors of stable juvenile osteochondritis dissecans knee lesions after 6 and 12 months of nonoperative treatment
Krause M, Hapfelmeier A, Möller M, Amling M, Bohndorf K, Meenen N
AM J SPORT MED. 2013;41(10):2384-91.

Bone microarchitecture of the talus changes with aging
Krause M, Rupprecht M, Mumme M, Püschel K, Amling M, Barvencik F
CLIN ORTHOP RELAT R. 2013;471(11):3663-71.

Osteocytic canalicular Networks: morphological implications for altered mechanosensitivity
Milovanovic P, Zimmermann E, Hahn M, Djonic D, Püschel K, Djuric M, Amling M, Busse B
ACS NANO. 2013;7(9):7542-51.

Sheep model for osteoporosis: sustainability and biomechanical relevance of low turnover osteoporosis induced by hypothalamic-pituitary disconnection.
Oheim R, Beil F, Köhne T, Wehner T, Barvencik F, Ignatius A, Amling M, Clarke I, Pogoda P
J ORTHOP RES. 2013;31(7):1067-1074.

Increased expression of transthyretin in leptin-deficient ob/ob mice is not causative for their major phenotypic abnormalities.
Rendenbach C, Ganswindt S, Seitz S, Barvencik F, Hübner A, Baranowsky A, Streichert T, Niemeier A, Heeren J, Amling M, Bartelt A, Schinke T
J NEUROENDOCRINOL. 2013;25(1):14-22.

Eleven year results of total hip arthroplasty in patients with secondary osteoarthritis due to slipped capital femoral epiphysis
Schoof B, Citak M, O'Loughlin P, Kendoff D, Haasper C, Gehrke T, Gebauer M
The open orthopaedics journal. 2013;7:158-62.

Inflammatory monocytes and Fcγ receptor IV on osteoclasts are critical for bone destruction during inflammatory arthritis in mice
Seeling M, Hillenhoff U, David J, Schett G, Tuckermann J, Lux A, Nimmerjahn F
P NATL ACAD SCI USA. 2013;110(26):10729-34.

Increased osteoblast and osteoclast indices in individuals with systemic mastocytosis
Seitz S, Barvencik F, Koehne T, Priemel M, Pogoda P, Semler J, Minne H, Pfeiffer M, Zustin J, Püschel K, zu Eulenburg C, Schinke T, Amling M
OSTEOPOROSIS INT. 2013;24(8):2325-34.

Impaired bone mineralization accompanied by low vitamin D and secondary hyperparathyroidism in patients with femoral neck fracture.
Seitz S, Koehne T, Ries C, Novo De Oliveira A, Barvencik F, Busse B, zu Eulenburg C, Schinke T, Püschel K, Rueger J, Amling M, Pogoda P
OSTEOPOROSIS INT. 2013;24(2):641-649.

Retinol deprivation partially rescues the skeletal mineralization defects of Phex-deficient Hyp mice.
Seitz S, Rendenbach C, Barvencik F, Streichert T, Jeschke A, Schulze J, Amling M, Schinke T
BONE. 2013;53(1):231-238.

Scaling of Haversian canal surface area to secondary osteon bone volume in ribs and limb bones
Skedros J, Knight A, Clark G, Crowder C, Dominguez V, Qiu S, Mulhern D, Donahue S, Busse B, Hulsey B, Zedda M, Sorenson S
AM J PHYS ANTHROPOL. 2013;151(2):230-44.

The SERM raloxifene improves diaphyseal fracture healing in mice
Spiro A, Khadem S, Jeschke A, Marshall R, Pogoda P, Ignatius A, Amling M, Beil F
J BONE MINER METAB. 2013;31(6):629-36.

Giant cell tumour of bone: reconstruction of the index metacarpophalangeal joint with an osteochondral graft from the lateral femoral condyle.
Spiro A, Pogoda P, Amling M, Meenen N, Zustin J, Rueger J, Priemel M
J PLAST RECONSTR AES. 2013;66(5):729-732.

Impaired bone formation and increased osteoclastogenesis in mice lacking chemokine (C-C motif) ligand 5 (Ccl5)
Wintges K, Beil F, Albers J, Jeschke A, Schweizer M, Claass B, Tiegs G, Amling M, Schinke T
J BONE MINER RES. 2013;28(10):2070-80.

Increased Col10a1 expression is not causative for the phenotype of Phex-deficient Hyp mice
Yorgan T, Rendenbach C, Jeschke A, Amling M, Cheah K, Schinke T
BIOCHEM BIOPH RES CO. 2013;442(3-4):209-13.

Osteochondritis dissecans of the tarsal navicular bone: a case report.
Beil F, Bruns J, Habermann C, Rüther W, Niemeier A
J AM PODIAT MED ASSN. 2012;102(4):338-342.

Low turnover osteoporosis in sheep induced by hypothalamic-pituitary disconnection.
Beil F, Oheim R, Barvencik F, Hissnauer T, Pestka J, Ignatius A, Rueger J, Schinke T, Clarke I, Amling M, Pogoda P
J ORTHOP RES. 2012;30(8):1254-1262.

The transcriptional profile of mesenchymal stem cell populations in primary osteoporosis is distinct and shows overexpression of osteogenic inhibitors.
Benisch P, Schilling T, Klein-Hitpass L, Frey S, Seefried L, Raaijmakers N, Krug M, Regensburger M, Zeck S, Schinke T, Amling M, Ebert R, Jakob F
PLOS ONE. 2012;7(9):45142.

Acceleration of collateral development by carcinoembryonic antigen-related cell adhesion molecule 1 expression on CD11b/⁺Gr-1⁺ myeloid cells--brief report
Bickert T, Marshall R, Zhang Z, Ludewig P, Binder M, Klinke A, Rottbauer W, Amling M, Wagener C, Ito W, Horst A
ARTERIOSCL THROM VAS. 2012;32(11):2566-8.

RSK2 protects mice against TNF-induced bone loss
Böhm C, Derer A, Axmann R, Hillienhoff U, Zaiss M, Luther J, Zech C, Stock M, Scholtysek C, Engelke K, Hess A, Tuckermann J, Schett G, David J
J CELL SCI. 2012;125(Pt 9):2160-71.

Breer S, Amling M, Püschel K, Klein A, Schulz F, Zustin J
RECHTSMEDIZIN. 2012;22(1):49-53.

Histological ex vivo analysis of retrieved human tantalum augmentations.
Breer S, Hahn M, Kendoff D, Krause M, Köhne T, Haasper C, Gehrke T, Amling M, Gebauer M
INT ORTHOP. 2012;36(11):2269-2274.

Analysis of retrieved hip resurfacing arthroplasties reveals the interrelationship between interface hyperosteoidosis and demineralization of viable bone trabeculae.
Breer S, Krause M, Busse B, Hahn M, Rüther W, Morlock M, Amling M, Zustin J
J ORTHOP RES. 2012;30(7):1155-1161.

Stress fractures in elderly patients.
Breer S, Krause M, Marshall R, Oheim R, Amling M, Barvencik F
INT ORTHOP. 2012;36(12):2581-2587.

Morphological characteristics of the developing proximal femur: a biomechanical perspective.
Djurić M, Milovanovic P, Djonić D, Minić A, Hahn M
SRP ARK CELOK LEK. 2012;140(11-12):738-745.

Estradiol increases hematopoietic stem and progenitor cells independent of its actions on bone.
Illing A, Liu P, Ostermay S, Schilling A, de Haan G, Krust A, Amling M, Chambon P, Schinke T, Tuckermann J
HAEMATOLOGICA. 2012;97(8):1131-1135.

Premature loss of bone remodeling compartment canopies is associated with deficient bone formation: a study of healthy individuals and patients with Cushing's syndrome.
Jensen P, Andersen T, Søe K, Hauge E, Bollerslev J, Amling M, Barvencik F, Delaissé J
J BONE MINER RES. 2012;27(4):770-780.

Divergent resorbability and effects on osteoclast formation of commonly used bone substitutes in a human in vitro-assay.
Keller J, Brink S, Busse B, Schilling A, Schinke T, Amling M, Lange T
PLOS ONE. 2012;7(10):46757.

Transgenic over-expression of interleukin-33 in osteoblasts results in decreased osteoclastogenesis.
Keller J, Catalá-Lehnen P, Wintges K, Schulze J, Bickert T, Ito W, Horst A, Amling M, Schinke T
BIOCHEM BIOPH RES CO. 2012;417(1):217-222.

Cementation and interface analysis of early failure cases after hip-resurfacing arthroplasty.
Krause M, Breer S, Hahn M, Rüther W, Morlock M, Amling M, Zustin J
INT ORTHOP. 2012;36(7):1333-1340.

Micro-structural basis for particular vulnerability of the superolateral neck trabecular bone in the postmenopausal women with hip fractures.
Milovanovic P, Djonic D, Marshall R, Hahn M, Nikolic S, Zivkovic V, Amling M, Djuric M
BONE. 2012;50(1):63-68.

The role of apolipoprotein E in bone metabolism.
Niemeier A, Schinke T, Heeren J, Amling M
BONE. 2012;50(2):518-524.

Large animal model for osteoporosis in humans: the ewe.
Oheim R, Amling M, Ignatius A, Pogoda P
EUR CELLS MATER. 2012;24:372-385.

Targeting the lateral but not the third ventricle induces bone loss in ewe: An experimental approach to generate an improved large animal model of osteoporosis.
Oheim R, Beil F, Barvencik F, Egermann M, Amling M, Clarke I, Pogoda P
J TRAUMA. 2012;72(3):720-726.

Surgical therapy of hip-joint empyema. Is the Girdlestone arthroplasty still up to date?
Oheim R, Gille J, Schoop R, Mägerlein S, Grimme C, Jürgens C, Gerlach U
INT ORTHOP. 2012;36(5):927-933.

Paget disease of the spine: an evaluation of 101 patients with a histomorphometric analysis of 29 cases.
Pestka J, Seitz S, Zustin J, Püschel K, Amling M, Barvencik F
EUR SPINE J. 2012;21(5):999-1006.

WNT5A is induced by inflammatory mediators in bone marrow stromal cells and regulates cytokine and chemokine production.
Rauner M, Stein N, Winzer M, Goettsch C, Zwerina J, Schett G, Distler J, Albers J, Schulze J, Schinke T, Bornhäuser M, Platzbecker U, Hofbauer L
J BONE MINER RES. 2012;27(3):575-585.

Changes to the cell, tissue and architecture levels in cranial suture synostosis reveal a problem of timing in bone development.
Regelsberger J, Milovanovic P, Schmidt T, Hahn M, Zimmermann E, Tsokos M, Zustin J, Ritchie R, Amling M, Busse B
EUR CELLS MATER. 2012;24:441-458.

p65-Dependent production of interleukin-1β by osteolytic prostate cancer cells causes an induction of chemokine expression in osteoblasts.
Schulze J, Riecken K, Baranowsky A, Streichert T, Lange T, Spiro A, Albers J, Seitz S, Zustin J, Amling M, Fehse B, Schinke T
CANCER LETT. 2012;317(1):106-113.

Pharmacological estrogen administration causes a FSH-independent osteo-anabolic effect requiring ER alpha in osteoblasts
Seitz S, Keller J, Schilling A, Jeschke A, Marshall R, Stride B, Wintermantel T, Beil F, Amling M, Schütz G, Tuckermann J, Schinke T
PLOS ONE. 2012;7(11):e50301.

Accelerated growth plate mineralization and foreshortened proximal limb bones in fetuin-A knockout mice
Seto J, Busse B, Gupta H, Schäfer C, Krauss S, Dunlop J, Masic A, Kerschnitzki M, Zaslansky P, Boesecke P, Catalá-Lehnen P, Schinke T, Fratzl P, Jahnen-Dechent W
PLOS ONE. 2012;7(10):e47338.

Mice over-expressing salmon calcitonin have strongly attenuated osteoarthritic histopathological changes after destabilization of the medial meniscus.
Sondergaard B, Catalá-Lehnen P, Hübner A, Bay-Jensen A, Schinke T, Henriksen K, Schilling A, Haberland M, Nielsen R, Amling M, Karsdal M
OSTEOARTHR CARTILAGE. 2012;20(2):136-143.

DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.
Abdallah B, Ditzel N, Mahmood A, Isa A, Traustadottir G, Schilling A, Ruiz-Hidalgo M, Laborda J, Amling M, Kassem M
J BONE MINER RES. 2011;26(7):1457-1471.

Control of bone formation by the serpentine receptor Frizzled-9.
Albers J, Schulze J, Beil F, Gebauer M, Baranowsky A, Keller J, Marshall R, Wintges K, Friedrich F, Priemel M, Schilling A, Rueger J, Cornils K, Fehse B, Streichert T, Sauter G, Jakob F, Insogna K, Pober B, Knobeloch K, Francke U, Amling M, Schinke T
J CELL BIOL. 2011;192(6):1057-1072.

Skeletal mineralization defects in adult hypophosphatasia-a clinical and histological analysis.
Barvencik F, Beil F, Gebauer M, Busse B, Köhne T, Seitz S, Zustin J, Pogoda P, Schinke T, Amling M
OSTEOPOROSIS INT. 2011;22(10):2667-2675.

Fracture prevention by femoroplasty--cement augmentation of the proximal femur.
Beckmann J, Springorum R, Vettorazzi E, Bachmeier S, Lüring C, Tingart M, Püschel K, Stark O, Grifka J, Gehrke T, Amling M, Gebauer M
J ORTHOP RES. 2011;29(11):1753-1758.

Effects of increased bone formation on fracture healing in mice.
Beil F, Barvencik F, Gebauer M, Beil B, Pogoda P, Rueger J, Ignatius A, Schinke T, Amling M
J TRAUMA. 2011;70(4):857-862.

The distal radius, the most frequent fracture localization in humans: a histomorphometric analysis of the microarchitecture of 60 human distal radii and its changes in aging.
Beil F, Barvencik F, Gebauer M, Mumme M, Beil B, Pogoda P, Rueger J, Püschel K, Amling M
J TRAUMA. 2011;70(1):154-158.

Proliferation of the synovial lining cell layer in suggested metal hypersensitivity.
Burkandt A, Katzer A, Thaler K, Volker V, Friedrich R, Rüther W, Amling M, Zustin J
IN VIVO. 2011;25(4):679-686.

Metaphyseal fracture healing follows similar biomechanical rules as diaphyseal healing.
Claes L, Reusch M, Göckelmann M, Ohnmacht M, Wehner T, Amling M, Beil F, Ignatius A
J ORTHOP RES. 2011;29(3):425-432.

Articulating spacers used in two-stage revision of infected hip and knee prostheses abrade with time.
Fink B, Rechtenbach A, Büchner H, Vogt S, Hahn M
CLIN ORTHOP RELAT R. 2011;469(4):1095-1102.

Sex differences in the morphological failure patterns following hip resurfacing arthroplasty.
Hinsch A, Vettorazzi E, Morlock M, Rüther W, Amling M, Zustin J
BMC MED. 2011;9:113.

Knochen-Implantat-Interface nach 5 Monaten bei einer zementfrei fixierten Sprunggelenksendoprothese (Zenith)
Jerosch J, Neuhäuser C, Zustin J, Hahn M
ORTHOP PRAX. 2011;46(11):535-538.

Trabecular reorganization in consecutive iliac crest biopsies when switching from bisphosphonate to strontium ranelate treatment.
Jobke B, Burghardt A, Muche B, Hahn M, Semler J, Amling M, Majumdar S, Busse B
PLOS ONE. 2011;6(8):23638.

Size dependent induction of proinflammatory cytokines and cytotoxicity of particulate beta-tricalciumphosphate in vitro.
Lange T, Schilling A, Peters F, Mujas J, Wicklein D, Amling M
BIOMATERIALS. 2011;32(17):4067-4075.

Midkine-deficiency increases the anabolic response of cortical bone to mechanical loading.
Liedert A, Mattausch L, Röntgen V, Blakytny R, Vogele D, Pahl M, Bindl R, Neunaber C, Schinke T, Harroch S, Amling M, Ignatius A
BONE. 2011;48(4):945-951.

Elevated Fra-1 expression causes severe lipodystrophy
Luther J, Driessler F, Megges M, Hess A, Herbort B, Mandic V, Zaiss M, Reichardt A, Zech C, Tuckermann J, Calkhoven C, Wagner E, Schett G, David J
J CELL SCI. 2011;124(Pt 9):1465-76.

Functional characterization of a novel mutation localized in the start codon of the tissue-nonspecific alkaline phosphatase gene.
Mentrup B, Marschall C, Barvencik F, Amling M, Plendl H, Jakob F, Beck C
BONE. 2011;48(6):1401-1408.

Short-term activation of liver X receptors inhibits osteoblasts but long-term activation does not have an impact on murine bone in vivo.
Prawitt J, Beil F, Marshall R, Bartelt A, Rüther W, Heeren J, Amling M, Staels B, Niemeier A
BONE. 2011;48(2):339-346.

Primary implant stability after maxillary sinus augmentation with autogenous mesenchymal stem cells: a biomechanical evaluation in rabbits.
Riecke B, Heiland M, Hothan A, Morlock M, Amling M, Blake F
CLIN ORAL IMPLAN RES. 2011;22(11):1242-1246.

Biomechanical evaluation for mechanisms of periprosthetic femoral fractures.
Rupprecht M, Sellenschloh K, Großterlinden L, Püschel K, Morlock M, Amling M, Rueger J, Lehmann W
J TRAUMA. 2011;70(4):62-66.

Telomerase-deficient mice exhibit bone loss owing to defects in osteoblasts and increased osteoclastogenesis by inflammatory microenvironment.
Saeed H, Abdallah B, Ditzel N, Catalá-Lehnen P, Qiu W, Amling M, Kassem M
J BONE MINER RES. 2011;26(7):1494-1505.

Interleukin-33 is expressed in differentiated osteoblasts and blocks osteoclast formation from bone marrow precursor cells.
Schulze J, Bickert T, Beil F, Zaiss M, Albers J, Wintges K, Streichert T, Klätschke K, Keller J, Hissnauer T, Spiro A, Gessner A, Schett G, Amling M, McKenzie A, Horst A, Schinke T
J BONE MINER RES. 2011;26(4):704-717.

How much vitamin D do we need for skeletal health?
von Domarus C, Brown J, Barvencik F, Amling M, Pogoda P
CLIN ORTHOP RELAT R. 2011;469(11):3127-3133.

Measurement of TLR-Induced Macrophage Spreading by Automated Image Analysis: Differential Role of Myd88 and MAPK in Early and Late Responses
Wenzel J, Held C, Palmisano R, Teufel S, David J, Wittenberg T, Lang R
FRONT PHYSIOL. 2011;2:71.

Apolipoprotein E-dependent inverse regulation of vertebral bone and adipose tissue mass in C57Bl/6 mice: modulation by diet-induced obesity.
Bartelt A, Beil F, Schinke T, Röser K, Ruether W, Heeren J, Niemeier A
BONE. 2010;47(4):736-745.

Die Moorleiche aus dem Mittelalter war Rechtshänder.
Barvencik F, Pestka J, Beil F, Marshall R, Fansa M, Amling M, Püschel K
2010. Das Kind aus der Esterweger Dose: Dokumentation einer außergewöhnlichen Skelett-Moorleiche. Isensee-Verlag: 63-68.

Effects of estrogen on fracture healing in mice.
Beil F, Barvencik F, Gebauer M, Seitz S, Rueger J, Ignatius A, Pogoda P, Schinke T, Amling M
J TRAUMA. 2010;69(5):1259-1265.

Fra-2/AP-1 controls bone formation by regulating osteoblast differentiation and collagen production.
Bozec A, Bakiri L, Jimenez M, Schinke T, Amling M, Wagner E
J CELL BIOL. 2010;190(6):1093-1106.

Decrease in the osteocyte lacunar density accompanied by hypermineralized lacunar occlusion reveals failure and delay of remodeling in aged human bone.
Busse B, Djonic D, Milovanovic P, Hahn M, Püschel K, Ritchie R, Djuric M, Amling M
AGING CELL. 2010;9(6):1065-1075.

Reorganization of the femoral cortex due to age-, sex-, and endoprosthetic-related effects emphasized by osteonal dimensions and remodeling.
Busse B, Hahn M, Schinke T, Püschel K, Duda G, Amling M
J BIOMED MATER RES A. 2010;92(4):1440-1451.

Region-specific sex-dependent pattern of age-related changes of proximal femoral cancellous bone and its implications on differential bone fragility.
Djuric M, Djonic D, Milovanovic P, Nikolic S, Marshall R, Marinkovic J, Hahn M
CALCIFIED TISSUE INT. 2010;86(3):192-201.

Identification of molecular markers for articular cartilage.
Hissnauer T, Baranowsky A, Pestka J, Streichert T, Wiegandt K, Goepfert C, Beil F, Albers J, Schulze J, Ueblacker P, Petersen J, Schinke T, Meenen N, Pörtner R, Amling M
OSTEOARTHR CARTILAGE. 2010;18(12):1630-1638.

R-spondin 1 protects against inflammatory bone damage during murine arthritis by modulating the Wnt pathway
Krönke G, Uderhardt S, Kim K, Stock M, Scholtysek C, Zaiss M, Surmann-Schmitt C, Luther J, Katzenbeisser J, David J, Abdollahi-Roodsaz S, Tran K, Bright J, Binnerts M, Akhmetshina A, Böhm C, Distler J, Joosten L, Schett G, Abo A
ARTHRITIS RHEUMATOL. 2010;62(8):2303-12.

Biomechanical evaluation of peri- and interprosthetic fractures of the femur.
Lehmann W, Rupprecht M, Hellmers N, Sellenschloh K, Briem D, Püschel K, Amling M, Morlock M, Rueger J
J TRAUMA. 2010;68(6):1459-1463.

Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones
Maes C, Goossens S, Bartunkova S, Drogat B, Coenegrachts L, Stockmans I, Moermans K, Nyabi O, Haigh K, Naessens M, Haenebalcke L, Tuckermann J, Tjwa M, Carmeliet P, Mandic V, David J, Behrens A, Nagy A, Carmeliet G, Haigh J
EMBO J. 2010;29(2):424-41.

The clock genes Period 2 and Cryptochrome 2 differentially balance bone formation.
Maronde E, Schilling A, Seitz S, Schinke T, Schmutz I, van der Horst G, Amling M, Albrecht U
PLOS ONE. 2010;5(7):11527.

Increased trabecular bone formation in mice lacking the growth factor midkine.
Neunaber C, Catalá-Lehnen P, Beil F, Marshall R, Kanbach V, Baranowsky A, Lehmann W, Streichert T, Ignatius A, Muramatsu T, Schinke T, Amling M
J BONE MINER RES. 2010;25(8):1724-1735.

Osteologische Untersuchungen einer Moorleiche aus dem Mittelalter.
Pestka J, Barvencik F, Beil F, Marshall R, Fansa M, Amling M, Püschel K
2010. Das Kind aus der Esterweger Dose: Dokumentation einer außergewöhnlichen Skelett-Moorleiche. Isensee-Verlag: 57-62.

Skeletal analysis and comparison of bog bodies from Northern European peat bogs.
Pestka J, Barvencik F, Beil F, Marshall R, Jopp E, Schilling A, Bauerochse A, Fansa M, Püschel K, Amling M
SCI NAT-HEIDELBERG. 2010;97(4):393-402.

Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor.
Rauch A, Seitz S, Baschant U, Schilling A, Illing A, Stride B, Kirilov M, Mandic V, Takacz A, Schmidt-Ullrich R, Ostermay S, Schinke T, Spanbroek R, Zaiss M, Angel P, Lerner U, David J, Reichardt H, Amling M, Schütz G, Tuckermann J
CELL METAB. 2010;11(6):517-531.

Synchrotron-microcomputed tomography studies of normal and pathological cranial sutures: further insight.
Regelsberger J, Schmidt T, Busse B, Herzen J, Tsokos M, Amling M, Beckmann F
J NEUROSURG-PEDIATR. 2010;5(3):238-242.

Novel complexities regarding BMPs and fracture healing.
Schinke T, Amling M
J BONE MINER RES. 2010;25(6):1193-1195.

Negative regulation of bone formation by the transmembrane Wnt antagonist Kremen-2.
Schulze J, Seitz S, Saito H, Schneebauer M, Marshall R, Baranowsky A, Busse B, Schilling A, Friedrich F, Albers J, Spiro A, Zustin J, Streichert T, Ellwanger K, Niehrs C, Amling M, Baron R, Schinke T
PLOS ONE. 2010;5(4):10309.

Preproenkephalin (Penk) is expressed in differentiated osteoblasts, and its deletion in Hyp mice partially rescues their bone mineralization defect.
Seitz S, Barvencik F, Gebauer M, Albers J, Schulze J, Streichert T, Amling M, Schinke T
CALCIFIED TISSUE INT. 2010;86(4):282-293.

High bone turnover and accumulation of osteoid in patients with neurofibromatosis 1.
Seitz S, Schnabel C, Busse B, Schmidt H, Beil F, Friedrich R, Schinke T, Mautner V, Amling M
OSTEOPOROSIS INT. 2010;21(1):119-127.

Blockade of Dickkopf (DKK)-1 induces fusion of sacroiliac joints
Uderhardt S, Diarra D, Katzenbeisser J, David J, Zwerina J, Richards W, Kronke G, Schett G
ANN RHEUM DIS. 2010;69(3):592-7.

Regulatory T cells protect from local and systemic bone destruction in arthritis
Zaiss M, Frey B, Hess A, Zwerina J, Luther J, Nimmerjahn F, Engelke K, Kollias G, Hünig T, Schett G, David J
J IMMUNOL. 2010;184(12):7238-46.

Increased bone density and resistance to ovariectomy-induced bone loss in FoxP3-transgenic mice based on impaired osteoclast differentiation
Zaiss M, Sarter K, Hess A, Engelke K, Böhm C, Nimmerjahn F, Voll R, Schett G, David J
ARTHRITIS RHEUMATOL. 2010;62(8):2328-38.

Phenotypic diversity in chondromyxoid fibroma reveals differentiation pattern of tumor mimicking fetal cartilage canals development: an immunohistochemical study.
Zustin J, Akpalo H, Gambarotti M, Priemel M, Rueger J, Lübke A, Reske D, Lange C, Püschel K, Lohmann C, Rüther W, Amling M, Alberghini M
AM J PATHOL. 2010;177(3):1072-1078.

Ibandronate: a review of its vertebral and nonvertebral antifracture efficacy.
Amling M, Kurth A
Womens Health (Lond Engl). 2009;5(5):467-473.

Age- and sex-related changes of humeral head microarchitecture: histomorphometric analysis of 60 human specimens.
Barvencik F, Gebauer M, Beil F, Vettorazzi E, Mumme M, Rupprecht M, Pogoda P, Wegscheider K, Rueger J, Pueschel K, Amling M

The alpha-isoform of p38 MAPK specifically regulates arthritic bone loss
Böhm C, Hayer S, Kilian A, Zaiss M, Finger S, Hess A, Engelke K, Kollias G, Krönke G, Zwerina J, Schett G, David J
J IMMUNOL. 2009;183(9):5938-47.

Increased calcium content and inhomogeneity of mineralization render bone toughness in osteoporosis: mineralization, morphology and biomechanics of human single trabeculae.
Busse B, Hahn M, Soltau M, Zustin J, Püschel K, Duda G, Amling M
BONE. 2009;45(6):1034-1043.

Mesenchymale Stammzellen bei Arthritis
David J, Zwerina J, Schett G
Z RHEUMATOL. 2009;68(3):228-33.

Proinflammatory and osteoclastogenic effects of beta-tricalciumphosphate and hydroxyapatite particles on human mononuclear cells in vitro.
Lange T, Schilling A, Peters F, Haag F, Morlock M, Rueger J, Amling M
BIOMATERIALS. 2009;30(29):5312-5318.

Bone mineralization defects and vitamin D deficiency: histomorphometric analysis of iliac crest bone biopsies and circulating 25-hydroxyvitamin D in 675 patients.
Priemel M, von Domarus C, Klatte T, Kessler S, Schlie J, Meier S, Proksch N, Pastor F, Netter C, Streichert T, Püschel K, Amling M

Value of a new fixed-combination pack of bisphosphonate, calcium and vitamin D in the therapy of osteoporosis: results of two quantitative patient research studies.
Ringe J, Fardellone P, Kruse H, Amling M, Geest v, Stefan A, Möller G
DRUG AGING. 2009;26(3):241-253.

The treatment of intertrochanteric fractures: results using an intramedullary nail with integrated cephalocervical screws and linear compression.
Rücker A, Rupprecht M, Gruber M, Gebauer M, Barvencik F, Briem D, Rueger J
J ORTHOP TRAUMA. 2009;23(1):22-30.

Impaired gastric acidification negatively affects calcium homeostasis and bone mass.
Schinke T, Schilling A, Baranowsky A, Seitz S, Marshall R, Linn T, Bläker M, Huebner A, Schulz A, Simon R, Gebauer M, Priemel M, Kornak U, Perkovic S, Barvencik F, Beil F, Andrea D, Frattini A, Streichert T, Püschel K, Villa A, Debatin K, Rueger J, Teti A, Zustin J, Sauter G, Amling M
NAT MED. 2009;15(6):674-681.

Osteolytic prostate cancer cells induce the expression of specific cytokines in bone-forming osteoblasts through a Stat3/5-dependent mechanism.
Schulze J, Albers J, Baranowsky A, Keller J, Spiro A, Streichert T, Zustin J, Amling M, Schinke T
BONE. 2009.

Paget's disease of bone: histologic analysis of 754 patients.
Seitz S, Priemel M, Zustin J, Beil F, Semler J, Minne H, Schinke T, Amling M
J BONE MINER RES. 2009;24(1):62-69.

Osteoidosteom. Minimal-invasive, bildwandlergesteuerte Resektion und histopathologische Diagnosesicherung mittels Diamanthohlfräsen
Spiro A, Zustin J, Habermann C, Meenen N, Sauter G, Amling M, Rueger J, Priemel M
ORTHOPADE. 2009;38(10):962-969.

Reply to Letter to the Editor: Association of Osteonecrosis and Failure of Hip Resurfacing Arthroplasty.
Zustin J, Amling M

Intraosseous lymphocytic infiltrates after hip resurfacing arthroplasty : a histopathological study on 181 retrieved femoral remnants.
Zustin J, Amling M, Krause M, Breer S, Hahn M, Morlock M, Rüther W, Sauter G
VIRCHOWS ARCH. 2009;454(5):581-588.

Association of osteonecrosis and failure of hip resurfacing arthroplasty.
Zustin J, Sauter G, Morlock M, Rüther W, Amling M

CT-gesteuerte Sakroplastie unter Verwendung insufflierbarer Ballons. Ergebnisse einer Machbarkeitstudie
Briem D, Grossterlinden L, Begemann P, Lehmann W, Rupprecht M, Nüchtern J, Barvencik F, Schumacher U, Rueger J
UNFALLCHIRURGIE. 2008;111(6):381-6.

Allocation of nonbirefringent wear debris: darkfield illumination associated with PIXE microanalysis reveals cobalt deposition in mineralized bone matrix adjacent to CoCr implants.
Busse B, Hahn M, Niecke M, Jobke B, Püschel K, Delling G, Katzer A
J BIOMED MATER RES A. 2008;87(2):536-545.

Cellular immune reconstitution after haploidentical transplantation in children
Handgretinger R, Chen X, Pfeiffer M, Schumm M, Müller I, Feuchtinger T, Hale G, Lang P
BIOL BLOOD MARROW TR. 2008;14(1 Suppl 1):59-65.

The role of calcitonin and alpha-calcitonin gene-related peptide in bone formation.
Hübner A, Keller J, Catalá-Lehnen P, Perkovic S, Streichert T, Emeson R, Amling M, Schinke T
ARCH BIOCHEM BIOPHYS. 2008;473(2):210-217.

Versagensgründe von Oberflächenersatzimplantaten der Hüfte. Eine Analyse von 250 Revisionspräparaten
Morlock M, Bishop N, Stahmer F, Zustin J, Sauter G, Hahn M, Krause M, Rüther W, Amling M
ORTHOPADE. 2008;37(7):695-703.

Denosumab--a novel strategy to prevent structural joint damage in patients with RA?
Schett G, David J
Nature clinical practice. Rheumatology. 2008;4(12):634-5.

The role of Wnt proteins in arthritis
Schett G, Zwerina J, David J
Nature clinical practice. Rheumatology. 2008;4(9):473-80.

Polyethylen-Abrieb: Ursache oder Folge einer Endoprothesenlockerung? Untersuchungen an festen und gelockerten Hüftendoprothesen
Busse B, Niecke M, Püschel K, Delling G, Katzer A, Hahn M
Z ORTHOP UNFALLCHIR. 2007;145(4):452-60.

[Polyethylene abrasion: cause or consequence of an endoprosthesis loosening? Investigations of firm and loosened hip implants]
Busse B, Niecke M, Püschel K, Delling G, Katzer A, Hahn M
Z ORTHOP UNFALLCHIR. 2007;145(4):452-460.

Osteoimmunology: a view from the bone
David J
ADV IMMUNOL. 2007;95:149-65.

Skelettale und kutane Charakteristika des nävoiden Basalzellkarzinomsyndroms (Gorlin-Goltz-Syndrom). Ergebnisse von 8 Patienten aus 12 Jahren
Rupprecht M, Mensing C, Barvencik F, Ittrich H, Heiland M, Rueger J, Amling M, Pogoda P
ROFO-FORTSCHR RONTG. 2007;179(6):618-26.

Computer-assisted screw insertion into the first sacral vertebra using a three-dimensional image intensifier: results of a controlled experimental investigation.
Briem D, Linhart W, Lehmann W, Begemann P, Adam G, Schumacher U, Cullinane D, Rueger J, Windolf J
EUR SPINE J. 2006;15(6):757-763.

[Fluorosis--a forgotten entity. Case report of a woman with coxarthrosis and newly diagnosed fluorosis].
Busse B, Jobke B, Werner M, Fuerst M, Rüther W, Delling G
PATHOLOGE. 2006;27(1):73-79.

Pathophysiologie und Pathomorphologie der Osteoporose
Priemel M, Münch C, Beil F, Ritzel H, Amling M
RADIOLOGE. 2006;46(10):831-8.

Response of primary fibroblasts and osteoblasts to plasma treated polyetheretherketone (PEEK) surfaces.
Briem D, Strametz S, Schröder K, Meenen N, Lehmann W, Linhart W, Ohl A, Rueger J
J MATER SCI-MATER M. 2005;16(7):671-677.

Gene disruption of Spred-2 causes dwarfism
Bundschu K, Knobeloch K, Ullrich M, Schinke T, Amling M, Engelhardt C, Renné T, Walter U, Schuh K
J BIOL CHEM. 2005;280(31):28572-80.

JNK1 is not essential for TNF-mediated joint disease
Köller M, Hayer S, Redlich K, Ricci R, David J, Steiner G, Smolen J, Wagner E, Schett G
ARTHRITIS RES THER. 2005;7(1):R166-73.

Mouse models in skeletal physiology and osteoporosis: experiences and data on 14,839 cases from the Hamburg Mouse Archives.
Pogoda P, Priemel M, Schilling A, Gebauer M, Catalá-Lehnen P, Barvencik F, Beil F, Münch C, Rupprecht M, Müldner C, Rueger J, Schinke T, Amling M
J BONE MINER METAB. 2005;23:97-102.

Distinct functions of junD in cardiac hypertrophy and heart failure
Ricci R, Eriksson U, Oudit G, Eferl R, Akhmedov A, Sumara I, Sumara G, Kassiri Z, David J, Bakiri L, Sasse B, Idarraga M, Rath M, Kurz D, Theussl H, Perriard J, Backx P, Penninger J, Wagner E
GENE DEV. 2005;19(2):208-13.

[Bone grafts endoscopically applied to the spine Ergebnisse der anterioren Fusion und therapeutische Konsequenzen]
Briem D, Windolf J, Lehmann W, Begemann P, Meenen N, Rueger J, Linhart W
UNFALLCHIRURGIE. 2004;107(12):1152-1161.

Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects
Kenner L, Hoebertz A, Beil F, Beil T, Keon N, Karreth F, Eferl R, Scheuch H, Szremska A, Amling M, Schorpp-Kistner M, Angel P, Wagner E
J CELL BIOL. 2004;164(4):613-23.

Evaluation experimenteller Knorpeldefekte mit der ultrahochauflösenden Mehrzeilen-CT im Vergleich zur Histologie
Stork A, Kemper J, Priemel M, Kummer T, Begemann P, Habermann C, Amling M, Adam G
ROFO-FORTSCHR RONTG. 2004;176(5):746-751.

Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53
Eferl R, Ricci R, Kenner L, Zenz R, David J, Rath M, Wagner E
CELL. 2003;112(2):181-92.

Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver
Behrens A, Sibilia M, David J, Möhle-Steinlein U, Tronche F, Schütz G, Wagner E
EMBO J. 2002;21(7):1782-90.

JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and -independent mechanisms
David J, Sabapathy K, Hoffmann O, Idarraga M, Wagner E
J CELL SCI. 2002;115(Pt 22):4317-25.

Increased bone mass is an unexpected phenotype associated with deletion of the calcitonin gene
Hoff A, Catala-Lehnen P, Thomas P, Priemel M, Rueger J, Nasonkin I, Bradley A, Hughes M, Ordonez N, Cote G, Amling M, Gagel R
J CLIN INVEST. 2002;110(12):1849-57.

Osteoclasts are essential for TNF-alpha-mediated joint destruction
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