Publikationen mit Beteiligung von Mitarbeitern der Klinik für Pädiatrische Hämatologie und Onkologie

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2017

Functional Outcomes and Quality of Life After Radical Prostatectomy Only Versus a Combination of Prostatectomy with Radiation and Hormonal Therapy
Adam M, Tennstedt P, Lanwehr D, Tilki D, Steuber T, Beyer B, Thederan I, Heinzer H, Haese A, Salomon G, Budäus L, Michl U, Pehrke D, Stattin P, Bernard J, Klaus B, Pompe R, Petersen C, Huland H, Graefen M, Schwarz R, Huber W, Loeb S, Schlomm T
EUR UROL. 2017;71(3):330-336.

Neurogenesis from Sox2 expressing cells in the adult cerebellar cortex
Ahlfeld J, Filser S, Schmidt F, Wefers A, Merk D, Glaß R, Herms J, Schüller U
SCI REP-UK. 2017;7(1):6137.

Primary and secondary hemophagocytic lymphohistiocytosis have different patterns of T-cell activation, differentiation and repertoire
Ammann S, Lehmberg K, Zur Stadt U, Janka-Schaub G, Rensing-Ehl A, Klemann C, Heeg M, Bode S, Fuchs I, Ehl S
EUR J IMMUNOL. 2017;47(2):364-373.

Tyrosine kinase fusion genes in pediatric BCR-ABL1-like acute lymphoblastic leukemia
Boer J, Steeghs E, Marchante J, Boeree A, Beaudoin J, Beverloo H, Kuiper R, Escherich G, van der Velden V, van der Schoot C, de Groot-Kruseman H, Pieters R, den Boer M
ONCOTARGET. 2017;8(3):4618-4628.

Enzymatic characterization of novel arylsulfatase A variants using human arylsulfatase A-deficient immortalized mesenchymal stromal cells
Böhringer J, Santer R, Schumacher N, Gieseke F, Cornils K, Pechan M, Kustermann-Kuhn B, Handgretinger R, Schöls L, Harzer K, Krägeloh-Mann I, Müller I
HUM MUTAT. 2017.

Resistance to anti-CD19/CD3 BiTE in acute lymphoblastic leukemia may be mediated by disrupted CD19 membrane trafficking
Braig F, Brandt A, Goebeler M, Tony H, Kurze A, Nollau P, Bumm T, Böttcher S, Bargou R, Binder M
BLOOD. 2017;129(1):100-104.

Identification of Tyrosine Phosphorylated Proteins by SH2 Domain Affinity Purification and Mass Spectrometry
Buhs S, Gerull H, Nollau P
Methods Mol Biol. 2017;1555:407-418.

SH2 Domain Histochemistry
Buhs S, Nollau P
Methods Mol Biol. 2017;1555:535-545.

ATOH1 Promotes Leptomeningeal Dissemination and Metastasis of Sonic Hedgehog Subgroup Medulloblastomas
Grausam K, Dooyema S, Bihannic L, Premathilake H, Morrissy A, Forget A, Schaefer A, Gundelach J, Macura S, Maher D, Wang X, Heglin A, Ge X, Zeng E, Puget S, Chandrasekar I, Surendran K, Bram R, Schüller U, Talyor M, Ayrault O, Zhao H
CANCER RES. 2017;77(14):3766-3777.

Liver transplantation as a potentially lifesaving measure in neuroblastoma stage 4S
Holsten T, Schuster T, Grabhorn E, Hero B, Frühwald M
PEDIATR HEMAT ONCOL. 2017;34(1):17-23.

Reverse phase protein arrays enable glioblastoma molecular subtyping
Hutter G, Sailer M, Azad T, von Bueren A, Nollau P, Frank S, Tostado C, Sarvepalli D, Ghosh A, Ritz M, Boulay J, Mariani L
J NEURO-ONCOL. 2017;131(3):437-448.

Evolution of disease activity and biomarkers on and off rapamycin in 28 patients with autoimmune lymphoproliferative syndrome
Klemann C, Esquivel M, Magerus-Chatinet A, Lorenz M, Fuchs I, Neveux N, Castelle M, Rohr J, Bettoni da Cunha C, Ebinger M, Kobbe R, Kremens B, Kollert F, Gambineri E, Lehmberg K, Seidel M, Siepermann K, Voelker T, Schuster V, Goldacker S, Schwarz K, Speckmann C, Picard C, Fischer A, Rieux-Laucat F, Ehl S, Rensing-Ehl A, Neven B
HAEMATOLOGICA. 2017;102(2):e52-e56.

Biophysical approaches promote advances in the understanding of von Willebrand factor processing and function
Löf A, Müller J, Benoit M, Brehm M
Adv Biol Regul. 2017;63:81-91.

Announcing cIMPACT-NOW: the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy
Louis D, Aldape K, Brat D, Capper D, Ellison D, Hawkins C, Paulus W, Perry A, Reifenberger G, Figarella-Branger D, Wesseling P, Batchelor T, Cairncross J, Pfister S, Rutkowski S, Weller M, Wick W, von Deimling A
ACTA NEUROPATHOL. 2017;133(1):1-3.

Medulloblastoma - experimental models and reality
Neumann J, Swartling F, Schüller U
ACTA NEUROPATHOL. 2017 [Epub ahead of print].

Mutations in EXTL3 Cause Neuro-immuno-skeletal Dysplasia Syndrome
Oud M, Tuijnenburg P, Hempel M, van Vlies N, Ren Z, Ferdinandusse S, Jansen M, Santer R, Johannsen J, Bacchelli C, Alders M, Li R, Davies R, Dupuis L, Cale C, Wanders R, Pals S, Ocaka L, James C, Müller I, Lehmberg K, Strom T, Engels H, Williams H, Beales P, Roepman R, Dias P, Brunner H, Cobben J, Hall C, Hartley T, Le Quesne Stabej P, Mendoza-Londono R, Davies E, de Sousa S, Lessel D, Arts H, Kuijpers T
AM J HUM GENET. 2017;100(2):281-296.

The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants
Pajtler K, Mack S, Ramaswamy V, Smith C, Witt H, Smith A, Hansford J, von Hoff K, Wright K, Hwang E, Frappaz D, Kanemura Y, Massimino M, Faure-Conter C, Modena P, Tabori U, Warren K, Holland E, Ichimura K, Giangaspero F, Castel D, von Deimling A, Kool M, Dirks P, Grundy R, Foreman N, Gajjar A, Korshunov A, Finlay J, Gilbertson R, Ellison D, Aldape K, Merchant T, Bouffet E, Pfister S, Taylor M
ACTA NEUROPATHOL. 2017;133(1):5-12.

Mutual A domain interactions in the force sensing protein von Willebrand factor
Posch S, Aponte-Santamaría C, Schwarzl R, Karner A, Radtke M, Gräter F, Obser T, König G, Brehm M, Gruber H, Netz R, Baldauf C, Schneppenheim R, Tampé R, Hinterdorfer P
J STRUCT BIOL. 2017;197(1):57-64.

Genotype-outcome correlations in pediatric AML
Rasche M, von Neuhoff C, Dworzak M, Bourquin J, Bradtke J, Göhring G, Escherich G, Fleischhack G, Graf N, Gruhn B, Haas O, Klingebiel T, Kremens B, Lehrnbecher T, von Stackelberg A, Tchinda J, Zemanova Z, Thiede C, von Neuhoff N, Zimmermann M, Creutzig U, Reinhardt D
LEUKEMIA. 2017 [Epub ahead of print].

Retrospective analysis on thermal injuries in children-Demographic, etiological and clinical data of German and Austrian pediatric hospitals 2006-2015-Approaching the new German burn registry
Tegtmeyer L, Herrnstadt G, Maier S, Thamm O, Klinke M, Reinshagen K, Koenigs I
BURNS. 2017 [Epub ahead of print].

Outcome in unresectable glioblastoma: MGMT promoter methylation makes the difference
Thon N, Thorsteinsdottir J, Eigenbrod S, Schüller U, Lutz J, Kreth S, Belka C, Tonn J, Niyazi M, Kreth F
J NEUROL. 2017;264(2):350-358.

K27M midline gliomas display malignant progression by imaging and histology
Vettermann F, Neumann J, Suchorska B, Bartenstein P, Giese A, Dorostkar M, Albert N, Schüller U
NEUROPATH APPL NEURO. 2017;43(5):458-462.

Left atrial active contractile function parameters assessed by cardiac MR are sensitive to myocardial iron
Wehbe M, Yamamura J, Fischer R, Grosse R, Berliner C, Graessner J, Lund G, Adam G, Schoennagel B
J MAGN RESON IMAGING. 2017;45(2):535-541.

Lineage switch under blinatumomab treatment of relapsed common acute lymphoblastic leukemia without MLL rearrangement
Zoghbi A, Zur Stadt U, Winkler B, Müller I, Escherich G
PEDIATR BLOOD CANCER. 2017 [Epub ahead of print].

2016

Mutations in AP3D1 associated with immunodeficiency and seizures define a new type of Hermansky-Pudlak syndrome
Ammann S, Schulz A, Krägeloh-Mann I, Dieckmann N, Niethammer K, Fuchs S, Eckl K, Plank R, Werner R, Altmüller J, Thiele H, Nürnberg P, Bank J, Strauss A, von Bernuth H, Zur Stadt U, Grieve S, Griffiths G, Lehmberg K, Hennies H, Ehl S
BLOOD. 2016;127(8):997-1006.

Long-term survival of an infant with an atypical teratoid/rhabdoid tumor following subtotal resection and low-cumulative dose chemotherapy: a case report
Arnhold V, Oyen F, Schneppenheim R, Haberl H, Koch A, Frühwald M, Hernáiz Driever P
CHILD NERV SYST. 2016;32(6):1157-61.

Improved 6-year overall survival in AT/RT - results of the registry study Rhabdoid 2007
Bartelheim K, Nemes K, Seeringer A, Kerl K, Buechner J, Boos J, Graf N, Dürken M, Gerss J, Hasselblatt M, Kortmann R, Teichert von Luettichau I, Nagel I, Nygaard R, Oyen F, Quiroga E, Schlegel P, Schmid I, Schneppenheim R, Siebert R, Solano-Paez P, Timmermann B, Warmuth-Metz M, Frühwald M
CANCER MED-US. 2016;5(8):1765-75.

Analysis of a cohort of 101 CDAII patients: description of 24 new molecular variants and genotype-phenotype correlations
Bianchi P, Schwarz K, Högel J, Fermo E, Vercellati C, Grosse R, van Wijk R, van Zwieten R, Barcellini W, Zanella A, Heimpel H
BRIT J HAEMATOL. 2016;175(4):696-704.

Unterarmgangrän bei "normaler" Gerinnung.
Blohm M, Lehmberg K, Schrum J, Helmke K, Ridderbusch I, Schneppenheim R, Singer D
Z GEBURTSH NEONATOL . 2016;220:133-134.

Prognostic value of rare IKZF1 deletion in childhood B-cell precursor acute lymphoblastic leukemia: an international collaborative study
Boer J, van der Veer A, Rizopoulos D, Fiocco M, Sonneveld E, de Groot-Kruseman H, Kuiper R, Hoogerbrugge P, Horstmann M, Zaliova M, Palmi C, Trka J, Fronkova E, Emerenciano M, do Socorro Pombo-de-Oliveira M, Mlynarski W, Szczepanski T, Nebral K, Attarbaschi A, Venn N, Sutton R, Schwab C, Enshaei A, Vora A, Stanulla M, Schrappe M, Cazzaniga G, Conter V, Zimmermann M, Moorman A, Pieters R, den Boer M
LEUKEMIA. 2016;30(1):32-8.

Feasibility of CD3/CD19 depletion of a bone marrow graft
Bonig H, Müller I
CYTOTHERAPY. 2016;18(10):1345-7.

Treatment and outcome of Ganglioneuroma and Ganglioneuroblastoma intermixed
Decarolis B, Simon T, Krug B, Leuschner I, Vokuhl C, Kaatsch P, von Schweinitz D, Klingebiel T, Müller I, Schweigerer L, Berthold F, Hero B
BMC CANCER. 2016;16:542.

MB3W1 is an orthotopic xenograft model for anaplastic medulloblastoma displaying cancer stem cell- and Group 3-properties
Dietl S, Schwinn S, Dietl S, Riedel S, Deinlein F, Rutkowski S, von Bueren A, Krauss J, Schweitzer T, Vince G, Picard D, Eyrich M, Rosenwald A, Ramaswamy V, Taylor M, Remke M, Monoranu C, Beilhack A, Schlegel P, Wölfl M
BMC CANCER. 2016;16(1):115.

Ferritin as an early marker of graft rejection after allogeneic hematopoietic stem cell transplantation in pediatric patients
Döring M, Cabanillas Stanchi K, Feucht J, Queudeville M, Teltschik H, Lang P, Feuchtinger T, Handgretinger R, Müller I
ANN HEMATOL. 2016;95(2):311-23.

Outcome of relapsed infant acute lymphoblastic leukemia treated on the interfant-99 protocol
Driessen E, de Lorenzo P, Campbell M, Felice M, Ferster A, Hann I, Vora A, Hovi L, Escherich G, Li C, Mann G, Leblanc T, Locatelli F, Biondi A, Rubnitz J, Schrappe M, Silverman L, Stary J, Suppiah R, Szczepanski T, Valsecchi M, Pieters R
LEUKEMIA. 2016;30(5):1184-1187.

Incidence and Risk Factors for Developing Dengue-Associated Hemophagocytic Lymphohistiocytosis in Puerto Rico, 2008 - 2013
Ellis E, Sharp T, Pérez-Padilla J, González L, Poole-Smith B, Lebo E, Baker C, Delorey M, Torres-Velasquez B, Ochoa E, Rivera-Garcia B, Díaz-Pinto H, Clavell L, Puig-Ramos A, Janka G, Janka-Schaub G, Tomashek K
PLOS NEGLECT TROP D. 2016;10(8):e0004939.

Canonical Wnt Signaling Drives Tumor-Like Lesions from Sox2-Positive Precursors of the Murine Olfactory Epithelium
Engel N, Neumann J, Ahlfeld J, Wefers A, Merk D, Ohli J, Schüller U
PLOS ONE. 2016;11(11):e0166690.

Complementarity determining region-independent recognition of a superantigen by B-cell antigen receptors of mantle cell lymphoma
Fichtner M, Spies E, Seismann H, Riecken K, Engels N, Gösch B, Dierlamm J, Gerull H, Nollau P, Klapper W, Dreyling M, Binder M, Trepel M
HAEMATOLOGICA. 2016;101(9):e378-81.

Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP-positive cells
Fielitz K, Althoff K, De Preter K, Nonnekens J, Ohli J, Elges S, Hartmann W, Klöppel G, Knösel T, Schulte M, Klein-Hitpass L, Beisser D, Reis H, Eyking A, Cario E, Schulte J, Schramm A, Schüller U
ONCOTARGET. 2016;7(46):74415-74426.

Pubertal Development in Pediatric Kidney Transplant Patients Receiving Mammalian Target of Rapamycin Inhibitors or Conventional Immunosuppression
Förster J, Ahlenstiel-Grunow T, Zapf A, Mynarek M, Pape L
TRANSPLANTATION. 2016;100(11):2461-2470.

Epidermal growth factor receptor overexpression is common and not correlated to gene copy number in ependymoma
Friedrich C, von Bueren A, Kolevatova L, Bernreuther C, Grob T, Sepulveda-Falla D, van den Boom L, Westphal M, Simon R, Glatzel M
CHILD NERV SYST. 2016;32(2):281-90.

Evidence of H3 K27M mutations in posterior fossa ependymomas
Gessi M, Capper D, Sahm F, Huang K, von Deimling A, Tippelt S, Fleischhack G, Scherbaum D, Alfer J, Juhnke B, von Hoff K, Rutkowski S, Warmuth-Metz M, Chavez L, Pfister S, Pietsch T, Jones D, Sturm D
ACTA NEUROPATHOL. 2016;132(4):635-7.

Mutating heme oxygenase-1 into a peroxidase causes a defect in bilirubin synthesis associated with microcytic anemia and severe hyperinflammation
Greil J, Verga-Falzacappa M, Echner N, Behnisch W, Bandapalli O, Pechanska P, Immenschuh S, Vijayan V, Balla J, Tsukahara H, Schneider M, Janka-Schaub G, Claus M, Longerich T, Muckenthaler M, Kulozik A
HAEMATOLOGICA. 2016;101(11):e436-e439.

Long-term Outcome of Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Juvenile Metachromatic Leukodystrophy Compared With Nontransplanted Control Patients
Groeschel S, Kühl J, Bley A, Kehrer C, Weschke B, Döring M, Böhringer J, Schrum J, Santer R, Kohlschütter A, Krägeloh-Mann I, Müller I
JAMA NEUROL. 2016;73(9):1133-40.

The Prevalence of Sickle Cell Disease and Its Implication for Newborn Screening in Germany (Hamburg Metropolitan Area)
Grosse R, Lukacs Z, Cobos P, Oyen F, Ehmen C, Muntau B, Timmann C, Noack B
PEDIATR BLOOD CANCER. 2016;63(1):168-70.

The minimum required level of donor chimerism in hereditary hemophagocytic lymphohistiocytosis
Hartz B, Marsh R, Rao K, Henter J, Jordan M, Filipovich L, Bader P, Beier R, Burkhardt B, Meisel R, Schulz A, Winkler B, Albert M, Greil J, Karasu G, Woessmann W, Corbaciologlu S, Gruhn B, Holter W, Kühl J, Lang P, Seidel M, Veys P, Löfstedt A, Ammann S, Ehl S, Janka G, Müller I, Lehmberg K
BLOOD. 2016;127(25):3281-90.

Poorly differentiated chordoma with SMARCB1/INI1 loss: a distinct molecular entity with dismal prognosis
Hasselblatt M, Thomas C, Hovestadt V, Schrimpf D, Johann P, Bens S, Oyen F, Peetz-Dienhart S, Crede Y, Wefers A, Vogel H, Riemenschneider M, Antonelli M, Giangaspero F, Bernardo M, Giannini C, Ud Din N, Perry A, Keyvani K, van Landeghem F, Sumerauer D, Hauser P, Capper D, Korshunov A, Jones D, Pfister S, Schneppenheim R, Siebert R, Frühwald M, Kool M
ACTA NEUROPATHOL. 2016;132(1):149-51.

Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes
Johann P, Erkek S, Zapatka M, Kerl K, Buchhalter I, Hovestadt V, Jones D, Sturm D, Hermann C, Segura Wang M, Korshunov A, Rhyzova M, Gröbner S, Brabetz S, Chavez L, Bens S, Gröschel S, Kratochwil F, Wittmann A, Sieber L, Geörg C, Wolf S, Beck K, Oyen F, Capper D, van Sluis P, Volckmann R, Koster J, Versteeg R, von Deimling A, Milde T, Witt O, Kulozik A, Ebinger M, Shalaby T, Grotzer M, Sumerauer D, Zamecnik J, Mora J, Jabado N, Taylor M, Huang A, Aronica E, Bertoni A, Radlwimmer B, Pietsch T, Schüller U, Schneppenheim R, Northcott P, Korbel J, Siebert R, Frühwald M, Lichter P, Eils R, Gajjar A, Hasselblatt M, Pfister S, Kool M
CANCER CELL. 2016;29(3):379-93.

A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation
Kaufman C, Mosimann C, Fan Z, Yang S, Thomas A, Ablain J, Tan J, Fogley R, van Rooijen E, Hagedorn E, Ciarlo C, White R, Matos D, Puller A, Santoriello C, Liao E, Young R, Zon L
SCIENCE. 2016;351(6272):aad2197.

Rapid Diagnosis of an AT/RT by the Detection of a Heterozygous SMARCB1 Germ Line Deletion in an Infant
Kerl K, Oyen F, Giannikopoulou D, Rössig C, Rellensmann G, Sandkötter J, Brentrup A, Selzer G, Schneppenheim R, Frühwald M
PEDIATR BLOOD CANCER. 2016;63(8):1451-3.

Allergic-like reactions to asparaginase: Atypical allergies without asparaginase inactivation
Kloos R, Pieters R, Escherich G, van der Sluis I
PEDIATR BLOOD CANCER. 2016;63(11):1928-34.

Decreased demand for olfactory periglomerular cells impacts on neural precursor cell viability in the rostral migratory stream
Langenfurth A, Gu S, Bautze V, Zhang C, Neumann J, Schüller U, Stock K, Wolf S, Maier A, Mastrella G, Pak A, Cheng H, Kälin R, Holmbeck K, Strotmann J, Kettenmann H, Glass R
SCI REP-UK. 2016;6:32203.

von Willebrand factor is dimerized by protein disulfide isomerase
Lippok S, Kolšek K, Löf A, Eggert D, Vanderlinden W, Müller J, König G, Obser T, Röhrs K, Schneppenheim S, Budde U, Baldauf C, Aponte-Santamaría C, Gräter F, Schneppenheim R, Rädler J, Brehm M
BLOOD. 2016;127(9):1183-91.

Shear-Induced Unfolding and Enzymatic Cleavage of Full-Length VWF Multimers
Lippok S, Radtke M, Obser T, Kleemeier L, Schneppenheim R, Budde U, Netz R, Rädler J
BIOPHYS J. 2016;110(3):545-54.

IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study
Li Y, Buijs-Gladdines J, Canté-Barrett K, Stubbs A, Vroegindeweij E, Smits W, van Marion R, Dinjens W, Horstmann M, Kuiper R, Buijsman R, Zaman G, van der Spek P, Pieters R, Meijerink J
PLOS MED. 2016;13(12):e1002200.

COBL is a novel hotspot for IKZF1 deletions in childhood acute lymphoblastic leukemia
Lopes B, Meyer C, Barbosa T, Stadt U, Horstmann M, Venn N, Heatley S, White D, Sutton R, Pombo-de-Oliveira M, Marschalek R, Emerenciano M
ONCOTARGET. 2016;7(33):53064-53073.

Your critical care patient may have HLH (hemophagocytic lymphohistiocytosis)
Machowicz R, Janka-Schaub G, Wiktor-Jedrzejczak W
CRIT CARE. 2016;20(1):215.

Childhood medulloblastoma
Massimino M, Biassoni V, Gandola L, Garrè M, Gatta G, Giangaspero F, Poggi G, Rutkowski S
CRIT REV ONCOL HEMAT. 2016;105:35-51.

Treosulfan based conditioning for allogeneic HSCT in children with chronic granulomatous disease: a multicentre experience
Morillo-Gutierrez B, Beier R, Rao K, Burroughs L, Schulz A, Ewins A, Gibson B, Sedlacek P, Krol L, Strahm B, Zaidman I, Kalwak K, Talano J, Woolfrey A, Fraser C, Meyts I, Müller I, Wachowiak J, Bernardo M, Veys P, Sykora K, Gennery A, Slatter M
BLOOD. 2016;128(3):440-8.

pH-Dependent Interactions in Dimers Govern the Mechanics and Structure of von Willebrand Factor
Müller J, Löf A, Mielke S, Obser T, Bruetzel L, Vanderlinden W, Lipfert J, Schneppenheim R, Benoit M
BIOPHYS J. 2016;111(2):312-22.

Force sensing by the vascular protein von Willebrand factor is tuned by a strong intermonomer interaction
Müller J, Mielke S, Löf A, Obser T, Beer C, Bruetzel L, Pippig D, Vanderlinden W, Lipfert J, Schneppenheim R, Benoit M
P NATL ACAD SCI USA. 2016;113(5):1208-13.

Von Willebrand factor regulates complement on endothelial cells
Noone D, Riedl M, Pluthero F, Bowman M, Liszewski M, Lu L, Quan Y, Balgobin S, Schneppenheim R, Schneppenheim S, Budde U, James P, Atkinson J, Palaniyar N, Kahr W, Licht C
KIDNEY INT. 2016;90(1):123-34.

Identification and characterization of the elusive mutation causing the historical von Willebrand Disease type IIC Miami
Obser T, Ledford-Kraemer M, Oyen F, Brehm M, Denis C, Marschalek R, Montgomery R, Sadler J, Schneppenheim S, Budde U, Schneppenheim R
J THROMB HAEMOST. 2016;14(9):1725-35.

Intraventricular etoposide safety and toxicity profile in children and young adults with refractory or recurrent malignant brain tumors
Pajtler K, Tippelt S, Siegler N, Reichling S, Zimmermann M, Mikasch R, Bode U, Gnekow A, Pietsch T, Benesch M, Rutkowski S, Fleischhack G
J NEURO-ONCOL. 2016;128(3):463-71.

Reply to letter that comments on 'Intraventricular methotrexate as part of primary therapy for children with infant and/or metastatic medulloblastoma
Pompe R, von Bueren A, Mynarek M, von Hoff K, Rutkowski S
EUR J CANCER. 2016;56:181-2.

Single molecule force spectroscopy data and BD- and MD simulations on the blood protein von Willebrand factor
Posch S, Aponte-Santamaría C, Schwarzl R, Karner A, Radtke M, Gräter F, Obser T, König G, Brehm M, Gruber H, Netz R, Baldauf C, Schneppenheim R, Tampé R, Hinterdorfer P
Data Brief. 2016;8:1080-7.

Risk assessment of relapse by lineage-specific monitoring of chimerism in children undergoing allogeneic stem cell transplantation for acute lymphoblastic leukemia
Preuner S, Peters C, Pötschger U, Daxberger H, Fritsch G, Geyeregger R, Schrauder A, von Stackelberg A, Schrappe M, Bader P, Ebell W, Eckert C, Lang P, Sykora K, Schrum J, Kremens B, Ehlert K, Albert M, Meisel R, Lawitschka A, Mann G, Panzer-Grümayer R, Güngör T, Holter W, Strahm B, Gruhn B, Schulz A, Woessmann W, Lion T
HAEMATOLOGICA. 2016;101(6):741-6.

Improved nutrition in adolescents and young adults after childhood cancer - INAYA study
Quidde J, von Grundherr J, Koch B, Bokemeyer C, Escherich G, Valentini L, Buchholz D, Schilling G, Stein A
BMC CANCER. 2016;16(1):872.

Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis
Ramaswamy V, Hielscher T, Mack S, Lassaletta A, Lin T, Pajtler K, Jones D, Luu B, Cavalli F, Aldape K, Remke M, Mynarek M, Rutkowski S, Gururangan S, McLendon R, Lipp E, Dunham C, Hukin J, Eisenstat D, Fulton D, van Landeghem F, Santi M, van Veelen M, Van Meir E, Osuka S, Fan X, Muraszko K, Tirapelli D, Oba-Shinjo S, Marie S, Carlotti C, Lee J, Rao A, Giannini C, Faria C, Nunes S, Mora J, Hamilton R, Hauser P, Jabado N, Petrecca K, Jung S, Massimi L, Zollo M, Cinalli G, Bognár L, Klekner A, Hortobágyi T, Leary S, Ermoian R, Olson J, Leonard J, Gardner C, Grajkowska W, Chambless L, Cain J, Eberhart C, Ahsan S, Massimino M, Giangaspero F, Buttarelli F, Packer R, Emery L, Yong W, Soto H, Liau L, Everson R, Grossbach A, Shalaby T, Grotzer M, Karajannis M, Zagzag D, Wheeler H, von Hoff K, Alonso M, Tuñon T, Schüller U, Zitterbart K, Sterba J, Chan J, Guzman M, Elbabaa S, Colman H, Dhall G, Fisher P, Fouladi M, Gajjar A, Goldman S, Hwang E, Kool M, Ladha H, Vera-Bolanos E, Wani K, Lieberman F, Mikkelsen T, Omuro A, Pollack I, Prados M, Robins H, Soffietti R, Wu J, Metellus P, Tabori U, Bartels U, Bouffet E, Hawkins C, Rutka J, Dirks P, Pfister S, Merchant T, Gilbert M, Armstrong T, Korshunov A, Ellison D, Taylor M
J CLIN ONCOL. 2016;34(21):2468-77.

Risk stratification of childhood medulloblastoma in the molecular era: the current consensus
Ramaswamy V, Remke M, Bouffet E, Bailey S, Clifford S, Doz F, Kool M, Dufour C, Vassal G, Milde T, Witt O, von Hoff K, Pietsch T, Northcott P, Gajjar A, Robinson G, Padovani L, André N, Massimino M, Pizer B, Packer R, Rutkowski S, Pfister S, Taylor M, Pomeroy S
ACTA NEUROPATHOL. 2016;131(6):821-31.

Fracture Healing Is Delayed in Immunodeficient NOD/scid‑IL2Rγcnull Mice
Rapp A, Bindl R, Recknagel S, Erbacher A, Müller I, Schrezenmeier H, Ehrnthaller C, Gebhard F, Ignatius A
PLOS ONE. 2016;11(2):e0147465.

Expert consensus on dynamics of laboratory tests for diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis
Ravelli A, Minoia F, Davì S, Horne A, Bovis F, Pistorio A, Aricò M, Avcin T, Behrens E, De Benedetti F, Filipovic A, Grom A, Henter J, Ilowite N, Jordan M, Khubchandani R, Kitoh T, Lehmberg K, Lovell D, Miettunen P, Nichols K, Ozen S, Pachlopnik Schmid J, Ramanan A, Russo R, Schneider R, Sterba G, Uziel Y, Wallace C, Wouters C, Wulffraat N, Demirkaya E, Brunner H, Martini A, Ruperto N, Cron R
BMJ OPEN. 2016;2(1):e000161.

2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis: A European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Collaborative Initiative
Ravelli A, Minoia F, Davì S, Horne A, Bovis F, Pistorio A, Aricò M, Avcin T, Behrens E, De Benedetti F, Filipovic L, Grom A, Henter J, Ilowite N, Jordan M, Khubchandani R, Kitoh T, Lehmberg K, Lovell D, Miettunen P, Nichols K, Ozen S, Pachlopnik Schmid J, Ramanan A, Russo R, Schneider R, Sterba G, Uziel Y, Wallace C, Wouters C, Wulffraat N, Demirkaya E, Brunner H, Martini A, Ruperto N, Cron R
ANN RHEUM DIS. 2016;75(3):481-9.

Relapse patterns and outcome after relapse in standard risk medulloblastoma: a report from the HIT-SIOP-PNET4 study
Sabel M, Fleischhack G, Tippelt S, Gustafsson G, Doz F, Kortmann R, Massimino M, Navajas A, von Hoff K, Rutkowski S, Warmuth-Metz M, Clifford S, Pietsch T, Pizer B, Lannering B
J NEURO-ONCOL. 2016;129(3):515-24.

Musculoskeletal manifestations in mucopolysaccharidosis type I (Hurler syndrome) following hematopoietic stem cell transplantation
Schmidt M, Breyer S, Löbel U, Yarar S, Stücker R, Ullrich K, Müller I, Muschol N
ORPHANET J RARE DIS. 2016;11(1):93.

Consensus definitions of 14 severe acute toxic effects for childhood lymphoblastic leukaemia Treatment: a Delphi consensus
Schmiegelow K, Attarbaschi A, Barzilai S, Escherich G, Frandsen T, Halsey C, Hough R, Jeha S, Kato M, Liang D, Mikkelsen T, Möricke A, Niinimäki R, Piette C, Putti M, Raetz E, Silverman L, Skinner R, Tuckuviene R, van der Sluis I, Zapotocka E
LANCET ONCOL. 2016;17(6):e231-9.

Multimodal therapy in children and adolescents with newly diagnosed atypical teratoid rhabdoid tumor: individual pooled data analysis and review of the literature
Schrey D, Lechón F, Malietzis G, Moreno L, Dufour C, Chi S, Lafay-Cousin L, von Hoff K, Athanasiou T, Marshall L, Zacharoulis S
J NEURO-ONCOL. 2016;126(1):81-90.

Rapid Capture Next-Generation Sequencing in Clinical Diagnostics of Kinase Pathway Aberrations in B-Cell Precursor ALL
Stadt U, Escherich G, Indenbirken D, Alawi M, Adao M, Horstmann M
PEDIATR BLOOD CANCER. 2016;63(7):1283-6.

Molecular Analysis of Hybrid Neurofibroma/Schwannoma Identifies Common Monosomy 22 and α-T-Catenin/CTNNA3 as a Novel Candidate Tumor Suppressor
Stahn V, Nagel I, Fischer-Huchzermeyer S, Oyen F, Schneppenheim R, Gesk S, Bohring A, Chikobava L, Young P, Gess B, Werner M, Senner V, Harder A
AM J PATHOL. 2016;186(12):3285-3296.

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs
Sturm D, Orr B, Toprak U, Hovestadt V, Jones D, Capper D, Sill M, Buchhalter I, Northcott P, Leis I, Ryzhova M, Koelsche C, Pfaff E, Allen S, Balasubramanian G, Worst B, Pajtler K, Brabetz S, Johann P, Sahm F, Reimand J, Mackay A, Carvalho D, Remke M, Phillips J, Perry A, Cowdrey C, Drissi R, Fouladi M, Giangaspero F, Łastowska M, Grajkowska W, Scheurlen W, Pietsch T, Hagel C, Gojo J, Lötsch D, Berger W, Slavc I, Haberler C, Jouvet A, Holm S, Hofer S, Prinz M, Keohane C, Fried I, Mawrin C, Scheie D, Mobley B, Schniederjan M, Santi M, Buccoliero A, Dahiya S, Kramm C, von Bueren A, von Hoff K, Rutkowski S, Herold-Mende C, Frühwald M, Milde T, Hasselblatt M, Wesseling P, Rößler J, Schüller U, Ebinger M, Schittenhelm J, Frank S, Grobholz R, Vajtai I, Hans V, Schneppenheim R, Zitterbart K, Collins V, Aronica E, Varlet P, Puget S, Dufour C, Grill J, Figarella-Branger D, Wolter M, Schuhmann M, Shalaby T, Grotzer M, van Meter T, Monoranu C, Felsberg J, Reifenberger G, Snuderl M, Forrester L, Koster J, Versteeg R, Volckmann R, van Sluis P, Wolf S, Mikkelsen T, Gajjar A, Aldape K, Moore A, Taylor M, Jones C, Jabado N, Karajannis M, Eils R, Schlesner M, Lichter P, von Deimling A, Pfister S, Ellison D, Korshunov A, Kool M
CELL. 2016;164(5):1060-72.

Treatment of graft failure with TNI-based reconditioning and haploidentical stem cells in paediatric patients
Teltschik H, Heinzelmann F, Gruhn B, Feuchtinger T, Schlegel P, Schumm M, Kremens B, Müller I, Ebinger M, Schwarze C, Ottinger H, Zips D, Handgretinger R, Lang P
BRIT J HAEMATOL. 2016;175(1):115-22.

Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups
Thomas C, Sill M, Ruland V, Witten A, Hartung S, Kordes U, Jeibmann A, Beschorner R, Keyvani K, Bergmann M, Mittelbronn M, Pietsch T, Felsberg J, Monoranu C, Varlet P, Hauser P, Olar A, Grundy R, Wolff J, Korshunov A, Jones D, Bewerunge-Hudler M, Hovestadt V, von Deimling A, Pfister S, Paulus W, Capper D, Hasselblatt M
NEURO-ONCOLOGY. 2016;18(6):790-6.

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors
Torchia J, Golbourn B, Feng S, Ho K, Sin-Chan P, Vasiljevic A, Norman J, Guilhamon P, Garzia L, Agamez N, Lu M, Chan T, Picard D, de Antonellis P, Khuong-Quang D, Planello A, Zeller C, Barsyte-Lovejoy D, Lafay-Cousin L, Letourneau L, Bourgey M, Yu M, Gendoo D, Dzamba M, Barszczyk M, Medina T, Riemenschneider A, Morrissy A, Ra Y, Ramaswamy V, Remke M, Dunham C, Yip S, Ng H, Lu J, Mehta V, Albrecht S, Pimentel J, Chan J, Somers G, Faria C, Roque L, Fouladi M, Hoffman L, Moore A, Wang Y, Choi S, Hansford J, Catchpoole D, Birks D, Foreman N, Strother D, Klekner A, Bognár L, Garami M, Hauser P, Hortobágyi T, Wilson B, Hukin J, Carret A, Van Meter T, Hwang E, Gajjar A, Chiou S, Nakamura H, Toledano H, Fried I, Fults D, Wataya T, Fryer C, Eisenstat D, Scheinemann K, Fleming A, Johnston D, Michaud J, Zelcer S, Hammond R, Afzal S, Ramsay D, Sirachainan N, Hongeng S, Larbcharoensub N, Grundy R, Lulla R, Fangusaro J, Druker H, Bartels U, Grant R, Malkin D, McGlade C, Nicolaides T, Tihan T, Phillips J, Majewski J, Montpetit A, Bourque G, Bader G, Reddy A, Gillespie G, Warmuth-Metz M, Rutkowski S, Tabori U, Lupien M, Brudno M, Schüller U, Pietsch T, Judkins A, Hawkins C, Bouffet E, Kim S, Dirks P, Taylor M, Erdreich-Epstein A, Arrowsmith C, De Carvalho D, Rutka J, Jabado N, Huang A
CANCER CELL. 2016;30(6):891-908.

EZH2 mutation in an adolescent with Weaver syndrome developing acute myeloid leukemia and secondary hemophagocytic lymphohistiocytosis
Usemann J, Ernst T, Schäfer V, Lehmberg K, Seeger K
AM J MED GENET A. 2016;170(5):1274-7.

Consensus expert recommendations for identification and management of asparaginase hypersensitivity and silent inactivation
van der Sluis I, Vrooman L, Pieters R, Baruchel A, Escherich G, Goulden N, Mondelaers V, de Toledo J, Rizzari C, Silverman L, Whitlock J
HAEMATOLOGICA. 2016;101(3):279-85.

Small cell undifferentiated (SCUD) hepatoblastomas: All malignant rhabdoid tumors?
Vokuhl C, Oyen F, Häberle B, von Schweinitz D, Schneppenheim R, Leuschner I
GENE CHROMOSOME CANC. 2016;55(12):925-931.

Treatment of Children and Adolescents With Metastatic Medulloblastoma and Prognostic Relevance of Clinical and Biologic Parameters
von Bueren A, Kortmann R, von Hoff K, Friedrich C, Mynarek M, Müller K, Goschzik T, Zur Mühlen A, Gerber N, Warmuth-Metz M, Soerensen N, Deinlein F, Benesch M, Zwiener I, Kwiecien R, Faldum A, Bode U, Fleischhack G, Hovestadt V, Kool M, Jones D, Northcott P, Kuehl J, Pfister S, Pietsch T, Rutkowski S
J CLIN ONCOL. 2016;34(34):4151-4160.

Influence of Cranial Radiotherapy on Outcome in Children With Acute Lymphoblastic Leukemia Treated With Contemporary Therapy
Vora A, Andreano A, Pui C, Hunger S, Schrappe M, Moericke A, Biondi A, Escherich G, Silverman L, Goulden N, Taskinen M, Pieters R, Horibe K, Devidas M, Locatelli F, Valsecchi M
J CLIN ONCOL. 2016;34(9):919-26.

The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia
Wojtuszkiewicz A, Assaraf Y, Hoekstra M, Sciarrillo R, Jansen G, Peters G, Pieters R, Sonneveld E, Escherich G, Kaspers G, Cloos J
HAEMATOLOGICA. 2016;101(7):e291-4.

2015

Force-sensitive autoinhibition of the von Willebrand factor is mediated by interdomain interactions
Aponte-Santamaria C, Huck V, Posch S, Bronowska A, Grässle S, Brehm M, Obser T, Schneppenheim R, Hinterdorfer P, Schneider S, Baldauf C, Grater F
BIOPHYS J. 2015;108(9):2312-21.

Force-sensitive autoinhibition of the von Willebrand factor mediated by inter-domain interactions
Aponte-Santamaría C, Huck V, Posch S, Bronowska A, Grässle S, Brehm M, Obser T, Schneppenheim R, Hinterdorfer P, Schneider S, Baldauf C, Gräter F
BIOPHYS J. 2015;108(9):2312-21.

Monitoring of Minimal Residual Disease After Allogeneic Stem-Cell Transplantation in Relapsed Childhood Acute Lymphoblastic Leukemia Allows for the Identification of Impending Relapse: Results of the ALL-BFM-SCT 2003 Trial
Bader P, Kreyenberg H, von Stackelberg A, Eckert C, Salzmann-Manrique E, Meisel R, Poetschger U, Stachel D, Schrappe M, Alten J, Schrauder A, Schulz A, Lang P, Müller I, Albert M, Willasch A, Klingebiel T, Peters C
J CLIN ONCOL. 2015;33(11):1275 - 84.

Radiation therapy for choroid plexus carcinoma patients with Li-Fraumeni Syndrome: advantageous or detrimental?
Bahar M, Kordes U, Tekautz T, Wolff J
ANTICANCER RES. 2015;35(5):3013-3017.

The Protein Tyrosine Phosphatase Rptpζ Suppresses Osteosarcoma Development in Trp53-Heterozygous Mice
Baldauf C, Jeschke A, Kanbach V, Catala-Lehnen P, Baumhoer D, Gerull H, Buhs S, Amling M, Nollau P, Harroch S, Schinke T
PLOS ONE. 2015;10(9):e0137745.

Bestimmung des hypophysären Eisengehaltes mittels Multi-Echo-MRT-R2 Messungen
Berliner C, Brehmer M, Fischer R, Grosse R, Karul M, Keller S, Schönnagel B, Wang J, Adam G, Yamamura J
ROFO-FORTSCHR RONTG. 2015;187(S 01):WISS105_1.

The syndrome of hemophagocytic lymphohistiocytosis in primary immunodeficiencies: implications for differential diagnosis and pathogenesis
Bode S, Ammann S, Al-Herz W, Bataneant M, Dvorak C, Gehring S, Gennery A, Gilmour K, Gonzalez-Granado L, Groß-Wieltsch U, Ifversen M, Lingman-Framme J, Matthes-Martin S, Mesters R, Meyts I, van Montfrans J, Pachlopnik Schmid J, Pai S, Soler-Palacin P, Schuermann U, Schuster V, Seidel M, Speckmann C, Stepensky P, Sykora K, Tesi B, Vraetz T, Waruiru C, Bryceson Y, Moshous D, Lehmberg K, Jordan M, Ehl S
HAEMATOLOGICA. 2015;100(7):978-88.

Platelet dependent von Willebrand factor activity. Nomenclature and methodology: communication from the SSC of the ISTH
Bodó I, Eikenboom J, Montgomery R, Patzke J, Schneppenheim R, Di Paola J
J THROMB HAEMOST. 2015;13(7):1345-1350.

BCR-ABL1-like cases in pediatric acute lymphoblastic leukemia: a comparison between DCOG/Erasmus MC and COG/St. Jude signatures
Boer J, Marchante J, Evans W, Horstmann M, Escherich G, Pieters R, Den Boer M
HAEMATOLOGICA. 2015;100(9):e354-7.

Neuropsychological Outcome of Children Treated for Standard Risk Medulloblastoma in the PNET4 European Randomized Controlled Trial of Hyperfractionated Versus Standard Radiation Therapy and Maintenance Chemotherapy
Câmara-Costa H, Resch A, Kieffer V, Lalande C, Poggi G, Kennedy C, Bull K, Calaminus G, Grill J, Doz F, Rutkowski S, Massimino M, Kortmann R, Lannering B, Dellatolas G, Chevignard M
INT J RADIAT ONCOL. 2015;92(5):978-85.

Consensus of German transplant centers on hematopoietic stem cell transplantation in Fanconi anemia
Chao M, Ebell W, Bader P, Beier R, Burkhardt B, Feuchtinger T, Handgretinger R, Hanenberg H, Koehl U, Kratz C, Kremens B, Lang P, Meisel R, Müller I, Roessig C, Sauer M, Schlegel P, Schulz A, Strahm B, Thol F, Sykora K
KLIN PADIATR. 2015;227(3):157-65.

Biomarker-driven stratification of disease-risk in non-metastatic medulloblastoma: Results from the multi-center HIT-SIOP-PNET4 clinical trial
Clifford S, Lannering B, Schwalbe E, Hicks D, O'Toole K, Nicholson S, Goschzik T, Zur Mühlen A, Figarella-Branger D, Doz F, Rutkowski S, Gustafsson G, Pietsch T
ONCOTARGET. 2015;6(36):38827-39.

A novel role for microphthalmia-associated transcription factor-regulated pigment epithelium-derived factor during melanoma progression
Dadras S, Lin R, Razavi G, Kawakami A, Du J, Feige E, Milner D, Loda M, Granter S, Detmar M, Widlund H, Horstmann M, Fisher D
AM J PATHOL. 2015;185(1):252-65.

Cytokine serum levels during post-transplant adverse events in 61 pediatric patients after hematopoietic stem cell transplantation
Döring M, Cabanillas Stanchi K, Mezger M, Erbacher A, Feucht J, Pfeiffer M, Lang P, Handgretinger R, Müller I
BMC CANCER. 2015;15:Art. 607.

Antifungal prophylaxis with posaconazole vs. fluconazole or itraconazole in pediatric patients with neutropenia
Döring M, Eikemeier M, Cabanillas Stanchi K, Hartmann U, Ebinger M, Schwarze C, Schulz A, Handgretinger R, Müller I
EUR J CLIN MICROBIOL. 2015;34(6):1189-1200.

A Case of a Bilateral Cicatricial Upper Eyelid Entropion After Hematopoietic Stem Cell Transplantation in Mucopolysaccharidosis Type I
Dulz S, Wagenfeld L, Richard G, Schrum J, Muschol N, Keserü M
Ophthal Plast Reconstr Surg. 2015.

Monitoring minimal residual disease in children with high-risk relapses of acute lymphoblastic leukemia: Prognostic relevance of early and late assessment
Eckert C, Hagedorn N, Sramkova L, Mann G, Panzer-Grümayer R, Peters C, Bourquin J, Klingebiel T, Borkhardt A, Cario G, Alten J, Escherich G, Astrahantseff K, Seeger K, Henze G, von Stackelberg A
LEUKEMIA. 2015;29(8):1648-1655.

Novel Patient with Late-Onset Familial Hemophagocytic Lymphohistiocytosis with STXBP2 Mutations Presenting with Autoimmune Hepatitis, Neurological Manifestations and Infections Associated with Hypogammaglobulinemia
Esmaeilzadeh H, Bemanian M, Nabavi M, Arshi S, Fallahpour M, Fuchs I, Zur Stadt U, Warnatz K, Ammann S, Ehl S, Lehmberg K, Rezaei N
J CLIN IMMUNOL. 2015;35(1):22-25.

Primitive neuroectodermal tumors of the brainstem in children treated according to the HIT Trials: clinical findings of a rare disease
Friedrich C, Warmuth-Metz M, von Bueren A, Nowak J, Bison B, von Hoff K, Pietsch T, Kortmann R, Rutkowski S
J NEUROSURG-PEDIATR. 2015;15(3):227-35.

Molecular stratification of medulloblastoma: Comparison of histological and genetic methods to detect Wnt activated tumors
Goschzik T, Zur Mühlen A, Kristiansen G, Haberler C, Stefanits H, Friedrich C, von Hoff K, Rutkowski S, Pfister S, Pietsch T
NEUROPATH APPL NEURO. 2015;41(2):135-144.

Late-onset hemophagocytic lymphohistiocytosis (HLH) in an adult female with Griscelli syndrome type 2 (GS2)
Henkes M, Finke J, Warnatz K, Ammann S, Stadt U, Janka-Schaub G, Brugger W
ANN HEMATOL. 2015;94(6):1057-60.

High-resolution genomic analysis does not qualify atypical plexus papilloma as a separate entity among choroid plexus tumors
Japp A, Gessi M, Messing-Jünger M, Denkhaus D, Zur Mühlen A, Wolff J, Hartung S, Kordes U, Klein-Hitpass L, Pietsch T
J NEUROPATH EXP NEUR. 2015;74(2):110-20.

Multipotent Mesenchymal Stromal Cells: Possible Culprits in Solid Tumors?
Johann P, Müller I
Stem Cells Int. 2015;2015:914632.

Generation of high-titre virus stocks using BrK.219, a B-cell line infected stably with recombinant Kaposi's sarcoma-associated herpesvirus
Kati S, Hage E, Mynarek M, Ganzenmueller T, Indenbirken D, Grundhoff A, Schulz T
J VIROL METHODS. 2015;217:79-86.

Detection of SMARCB1 loss in ascites cells in the diagnosis of an abdominal rhabdoid tumor
Kerl K, Oyen F, Leuschner I, Schneppenheim R, Nagel I, Siebert R, Groll A, Hartmann W, Barth P, Bartelheim K, Seringer A, Wardelmann E, Frühwald M
PEDIATR BLOOD CANCER. 2015;62(5):897-900.

Risk of Rotavirus Vaccination for Children with SCID
Klinkenberg D, Blohm M, Hoehne M, Mas Marques A, Malecki M, Schildgen V, Schneppenheim R, Müller I, Schildgen O, Kobbe R
PEDIATR INFECT DIS J. 2015;34(1):114-5.

Donor choice in haploidentical stem cell transplantation: fetal microchimerism is associated with better outcome in pediatric leukemia patients
Kruchen A, Stahl T, Gieseke F, Binder T, Özcan Z, Meisel R, Kreyenberg H, Bader P, Gruhn B, Greil J, Pfeiffer M, Döring M, Handgretinger R, Fehse B, Müller I
BONE MARROW TRANSPL. 2015;50(10):1367-1370.

Out of the haemophagocytic lymphohistiocytosis niche
Lehmberg K
LANCET HAEMATOL. 2015;2(12):e508-9.

Consensus recommendations for the diagnosis and management of hemophagocytic lymphohistiocytosis associated with malignancies
Lehmberg K, Nichols K, Henter J, Girschikofsky M, Greenwood T, Jordan M, Kumar A, Minkov M, La Rosée P, Weitzman S
HAEMATOLOGICA. 2015;100(8):997-1004.

Malignancy-associated haemophagocytic lymphohistiocytosis in children and adolescents
Lehmberg K, Sprekels B, Nichols K, Woessmann W, Müller I, Suttorp M, Bernig T, Beutel K, Bode S, Kentouche K, Kolb R, Längler A, Minkov M, Schilling F, Schmid I, Vieth S, Ehl S, Zur Stadt U, Janka G
BRIT J HAEMATOL. 2015;170(4):539-49.

Clinical and Molecular Characterization of Patients with Heterozygous Mutations in Wilms Tumor Suppressor Gene 1
Lehnhardt A, Karnatz N, Ahlenstiel-Grunow T, Benz K, Benz M, Budde K, Büscher A, Fehr T, Feldkötter M, Graf N, Höcker B, Jungraithmayr T, Klaus G, Koehler B, Konrad M, Kranz B, Montoya C, Müller D, Neuhaus T, Oh J, Pape L, Pohl M, Royer-Pokora B, Querfeld U, Schneppenheim R, Staude H, Spartà G, Timmermann K, Wilkening F, Wygoda S, Bergmann C, Kemper M
CLIN J AM SOC NEPHRO. 2015;10(5):825-831.

Severe neurotoxicity following intrathecal methotrexate with nitrous oxide sedation in a child with acute lymphoblastic leukemia
Löbel U, Trah J, Escherich G
PEDIATR BLOOD CANCER. 2015;62(3):539-41.

KRAS and CREBBP mutations: a relapse-linked malicious liaison in childhood high hyperdiploid acute lymphoblastic leukemia
Malinowska-Ozdowy K, Frech C, Schönegger A, Eckert C, Cazzaniga G, Stanulla M, Zur Stadt U, Mecklenbräuker A, Schuster M, Kneidinger D, von Stackelberg A, Locatelli F, Schrappe M, Horstmann M, Attarbaschi A, Bock C, Mann G, Haas O, Panzer-Grümayer R
LEUKEMIA. 2015;29(8):1656-1667.

Platelet-type von Willebrand Disease: Diagnostic Challenges. Flaws and Pitfalls Experienced in the THROMKID Quality Project
Maurer M, Mesters R, Schneppenheim R, Knoefler R, Streif W
KLIN PADIATR. 2015;227(3):131-6.

Delayed Diagnosis of Platelet-type von Willebrand Disease in a 72-year-old Lady
Maurer M, Mesters R, Schneppenheim R, Streif W
KLIN PADIATR. 2015;227(3):171-172.

Klinische Praxis - Spenderfindung und Stammzelltransplantation
Müller I
2015. Rettende Geschwister. Schües C, Rehmann-Sutter C (Hrsg.). 2015. Aufl. Münster: Mentis, 25 - 32.

Systematic comparison of MRI findings in pediatric ependymoblastoma with ependymoma and CNS primitive neuroectodermal tumor not otherwise specified
Nowak J, Seidel C, Pietsch T, Alkonyi B, Fuss T, Friedrich C, von Hoff K, Rutkowski S, Warmuth-Metz M
NEURO-ONCOLOGY. 2015;17(8):1157-65.

Localization of SHH medulloblastoma in mice depends on the age at its initiation
Ohli J, Neumann J, Grammel D, Schüller U
ACTA NEUROPATHOL. 2015;130(2):307-9.

Neuropsychological short assessment of disease- and treatment-related intelligence deficits in children with brain tumours
Ottensmeier H, Zimolong B, Wolff J, Ehrich J, Galley N, von Hoff K, Kuehl J, Rutkowski S
EUR J PAEDIATR NEURO. 2015;19(3):298-307.

Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups
Pajtler K, Witt H, Sill M, Jones D, Hovestadt V, Kratochwil F, Wani K, Tatevossian R, Punchihewa C, Johann P, Reimand J, Warnatz H, Ryzhova M, Mack S, Ramaswamy V, Capper D, Schweizer L, Sieber L, Wittmann A, Huang Z, van Sluis P, Volckmann R, Koster J, Versteeg R, Fults D, Toledano H, Avigad S, Hoffman L, Donson A, Foreman N, Hewer E, Zitterbart K, Gilbert M, Armstrong T, Gupta N, Allen J, Karajannis M, Zagzag D, Hasselblatt M, Kulozik A, Witt O, Collins V, von Hoff K, Rutkowski S, Pietsch T, Bader G, Yaspo M, von Deimling A, Lichter P, Taylor M, Gilbertson R, Ellison D, Aldape K, Korshunov A, Kool M, Pfister S
CANCER CELL. 2015;27(5):728-43.

Stem-cell transplantation in children with acute lymphoblastic leukemia: A prospective international multicenter trial comparing sibling donors with matched unrelated donors-The ALL-SCT-BFM-2003 trial
Peters C, Schrappe M, von Stackelberg A, Schrauder A, Bader P, Ebell W, Lang P, Sykora K, Schrum J, Kremens B, Ehlert K, Albert M, Meisel R, Matthes-Martin S, Gungor T, Holter W, Strahm B, Gruhn B, Schulz A, Woessmann W, Poetschger U, Zimmermann M, Klingebiel T
J CLIN ONCOL. 2015;33(11):1265-74.

Pancreatic iron and fat assessment by MRI-R2* in patients with iron overload diseases
Pfeifer C, Schoennagel B, Grosse R, Wang Z, Graessner J, Nielsen P, Adam G, Fischer R, Yamamura J
J MAGN RESON IMAGING. 2015.

Intraventricular methotrexate as part of primary therapy for children with infant and/or metastatic medulloblastoma: Feasibility, acute toxicity and evidence for efficacy
Pompe R, von Bueren A, Mynarek M, von Hoff K, Friedrich C, Kwiecien R, Treulieb W, Lindow C, Deinlein F, Fleischhack G, Kuehl J, Rutkowski S
EUR J CANCER. 2015;51(17):2634-2642.

Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration
Pui C, Yang J, Hunger S, Pieters R, Schrappe M, Biondi A, Vora A, Baruchel A, Silverman L, Schmiegelow K, Escherich G, Horibe K, Benoit Y, Izraeli S, Yeoh A, Liang D, Downing J, Evans W, Relling M, Mullighan C
J CLIN ONCOL. 2015;33(27):2938-48.

Systemic mesenchymal stem cell administration enhances bone formation in fracture repair but not load-induced bone formation
Rapp A, Bindl R, Heilmann A, Erbacher A, Müller I, Brenner R, Ignatius A
EUR CELLS MATER. 2015;29:22-34.

A 2013/2014 northern hemisphere season surface antigen inactivated trivalent influenza vaccine - Assessing the immunogenicity and safety in an open label, uncontrolled study
Roggelin L, Vinnemeier C, Meyer S, Witte K, Marx L, Theeß W, Burchard G, Rolling T, Cramer J
HUM VACC IMMUNOTHER . 2015;11(10):2370-5.

Psychische Belastungen von Kindern und Jugendlichen nach einer Leukämie oder Lymphomerkrankung
Sautier L, Sarkar S, Petersen M, Mehnert A, Escherich G
PRAX KINDERPSYCHOL K. 2015;64(4):273-289.

Identification and Characterization of Novel Variations in Platelet G-Protein Coupled Receptor (GPCR) Genes in Patients Historically Diagnosed with Type 1 von Willebrand Disease
Stockley J, Nisar S, Leo V, Sabi E, Cunningham M, Eikenboom J, Lethagen S, Schneppenheim R, Goodeve A, Watson S, Mundell S, Daly M
PLOS ONE. 2015;10(12):e0143913.

Strategies to improve the quality of survival for childhood brain tumour survivors
Tallen G, Resch A, Calaminus G, Wiener A, Leiss U, Pletschko T, Friedrich C, Langer T, Grabow D, Driever P, Kortmann R, Timmermann B, Pietsch T, Warmuth-Metz M, Bison B, Thomale U, Krauss J, Mynarek M, von Hoff K, Ottensmeier H, Frühwald M, Kramm C, Temming P, Müller H, Witt O, Kordes U, Fleischhack G, Gnekow A, Rutkowski S
EUR J PAEDIATR NEURO. 2015;19(6):619-39.

Pediatric atypical choroid plexus papilloma reconsidered: increased mitotic activity is prognostic only in older children
Thomas C, Ruland V, Kordes U, Hartung S, Capper D, Pietsch T, Gerß J, Wolff J, Paulus W, Hasselblatt M
ACTA NEUROPATHOL. 2015;129(6):925-7.

Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis
Torchia J, Picard D, Lafay-Cousin L, Hawkins C, Kim S, Letourneau L, Ra Y, Ho K, Chan T, Sin-Chan P, Dunham C, Yip S, Ng H, Lu J, Albrecht S, Pimentel J, Chan J, Somers G, Zielenska M, Faria C, Roque L, Baskin B, Birks D, Foreman N, Strother D, Klekner A, Garami M, Hauser P, Hortobágyi T, Bognár L, Wilson B, Hukin J, Carret A, Van Meter T, Nakamura H, Toledano H, Fried I, Fults D, Wataya T, Fryer C, Eisenstat D, Scheineman K, Johnston D, Michaud J, Zelcer S, Hammond R, Ramsay D, Fleming A, Lulla R, Fangusaro J, Sirachainan N, Larbcharoensub N, Hongeng S, Barakzai M, Montpetit A, Stephens D, Grundy R, Schüller U, Nicolaides T, Tihan T, Phillips J, Taylor M, Rutka J, Dirks P, Bader G, Warmuth-Metz M, Rutkowski S, Pietsch T, Judkins A, Jabado N, Bouffet E, Huang A
LANCET ONCOL. 2015;16(5):569-82.

Incidence, Trends, and Survival of Children With Embryonal Tumors
Tulla M, Berthold F, Graf N, Rutkowski S, von Schweinitz D, Spix C, Kaatsch P
PEDIATRICS. 2015;136(3):e623-32.

Metastatic medulloblastoma in adults: outcome of patients treated according to the HIT2000 protocol
von Bueren A, Friedrich C, von Hoff K, Kwiecien R, Müller K, Pietsch T, Warmuth-Metz M, Hau P, Benesch M, Kuehl J, Kortmann R, Rutkowski S
EUR J CANCER. 2015;51(16):2434-43.

Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia
Wojtuszkiewicz A, Peters G, van Woerden N, Dubbelman B, Escherich G, Schmiegelow K, Sonneveld E, Pieters R, van de Ven P, Jansen G, Assaraf Y, Kaspers G, Cloos J
HEMATOL ONCOL. 2015;8:61.

Standardization of Good Manufacturing Practice-compliant production of bone marrow-derived human mesenchymal stromal cells for immunotherapeutic applications
Wuchter P, Bieback K, Schrezenmeier H, Bornhäuser M, Müller L, Bönig H, Wagner W, Meisel R, Pavel P, Tonn T, Lang P, Müller I, Renner M, Malcherek G, Saffrich R, Buss E, Horn P, Rojewski M, Schmitt A, Ho A, Sanzenbacher R, Schmitt M
CYTOTHERAPY. 2015;17(2):128-139.

2014

Germline de novo mutations and linkage markers vs. DNA sequencing for carrier detection in von Willebrand disease
Ahmad F, Oyen F, Jan R, Budde U, Schneppenheim R, Saxena R
HAEMOPHILIA. 2014;20(4):e311-e317.

EMP1, a novel poor prognostic factor in pediatric leukemia regulates prednisolone resistance, cell proliferation, migration and adhesion
Ariës I, Jerchel I, van den Dungen R, van den Berk L, Boer J, Horstmann M, Escherich G, Pieters R, den Boer M
LEUKEMIA. 2014;28(9):1828-1837.

Clinical and genetic features of rhabdoid tumors of the heart registered with the European Rhabdoid Registry (EU-RHAB)
Bartelheim K, Sumerauer D, Behrends U, Kodetova D, Kucera F, Leuschner I, Neumayer P, Oyen F, Rübe C, Siebert R, Schneppenheim R, Seeringer A, Vasovcak P, Frühwald M
CANCER GENET-NY. 2014;207(9):379-83.

High-dose chemotherapy (HDCT) with auto-SCT in children with atypical teratoid/rhabdoid tumors (AT/RT): a report from the European Rhabdoid Registry (EU-RHAB)
Benesch M, Bartelheim K, Fleischhack G, Gruhn B, Schlegel P, Witt O, Stachel K, Hauch H, Urban C, Quehenberger F, Massimino M, Pietsch T, Hasselblatt M, Giangaspero F, Kordes U, Schneppenheim R, Hauser P, Klingebiel T, Frühwald M
BONE MARROW TRANSPL. 2014;49(3):370-5.

Hemophagocytic lymphohistiocytosis in imported pediatric visceral leishmaniasis in a nonendemic area
Bode S, Bogdan C, Beutel K, Behnisch W, Greiner J, Henning S, Jorch N, Jankofsky M, Jakob M, Schmid I, Veelken N, Vraetz T, Janka G, Ehl S, Lehmberg K
J PEDIATR-US. 2014;165(1):147-153.e1.

Treatment of recurrent primitive neuroectodermal tumors (PNET) in children and adolescents with high-dose chemotherapy (HDC) and stem cell Support: results of the HITREZ 97 multicentre trial
Bode U, Zimmermann M, Moser O, Rutkowski S, Warmuth-Metz M, Pietsch T, Kortmann R, Faldum A, Fleischhack G
J NEURO-ONCOL. 2014;120(3):635-42.

von Willebrand disease type 2A phenotypes IIC, IID and IIE: A day in the life of shear-stressed mutant von Willebrand factor
Brehm M, Huck V, Aponte-Santamaría C, Obser T, Grässle S, Oyen F, Budde U, Schneppenheim S, Baldauf C, Gräter F, Schneider S, Schneppenheim R
THROMB HAEMOSTASIS. 2014;112(1):96-108.

Interactions of von Willebrand factor and ADAMTS13 in von Willebrand disease and thrombotic thrombocytopenic purpura
Budde U, Schneppenheim R
HAMOSTASEOLOGIE. 2014;34(3):215-25.

Acute lymphoblastic leukemia in children with Down Syndrome: a retrospective analysis from the Ponte di Legno study group
Buitenkamp T, Izraeli S, Zimmermann M, Forestier E, Heerema N, van den Heuvel-Eibrink M, Pieters R, Korbijn C, Silverman L, Schmiegelow K, Liang D, Horibe K, Arico M, Biondi A, Basso G, Rabin K, Schrappe M, Cario G, Mann G, Morak M, Panzer-Grümayer R, Mondelaers V, Lammens T, Cavé H, Stark B, Ganmore I, Moorman A, Vora A, Hunger S, Pui C, Mullighan C, Manabe A, Escherich G, Kowalczyk J, Whitlock J, Zwaan C
BLOOD. 2014;123(1):70-77.

Acquired hemophilia A and von Willebrand syndrome in a patient with late-onset systemic lupus erythematosus
Dicke C, Holstein K, Schneppenheim S, Dittmer R, Schneppenheim R, Bokemeyer C, Iking-Konert C, Budde U, Langer F
Exp Hematol Oncol. 2014;3:21.

Adults with CNS primitive neuroectodermal tumors/pineoblastomas: results of multimodal treatment according to the pediatric HIT 2000 protocol
Friedrich C, Müller K, von Hoff K, Kwiecien R, Pietsch T, Warmuth-Metz M, Gerber N, Hau P, Kuehl J, Kortmann R, von Bueren A, Rutkowski S
J NEURO-ONCOL. 2014;116(3):567-575.

LASP1 is a novel BCR-ABL substrate and a phosphorylation-dependent binding partner of CRKL in chronic myeloid leukemia
Frietsch J, Kastner C, Grunewald T, Schweigel H, Nollau P, Ziermann J, Clement J, La Rosée P, Hochhaus A, Butt E
ONCOTARGET. 2014;5(14):5257-71.

Identification of novel NOTCH1 mutations: increasing our knowledge of the NOTCH signaling pathway
Gallo Llorente L, Luther H, Schneppenheim R, Zimmermann M, Felice M, Horstmann M
PEDIATR BLOOD CANCER. 2014;61(5):788-96.

Recent developments and current concepts in medulloblastoma
Gerber N, Mynarek M, von Hoff K, Friedrich C, Resch A, Rutkowski S
CANCER TREAT REV. 2014;40(3):356-365.

Treatment of children with central nervous system primitive neuroectodermal tumors/pinealoblastomas in the prospective multicentric trial HIT 2000 using hyperfractionated radiation therapy followed by maintenance chemotherapy
Gerber N, von Hoff K, Resch A, Ottensmeier H, Kwiecien R, Faldum A, Matuschek C, Hornung D, Bremer M, Benesch M, Pietsch T, Warmuth-Metz M, Kuehl J, Rutkowski S, Kortmann R
INT J RADIAT ONCOL. 2014;89(4):863-71.

MYCN amplification predicts poor outcome for patients with supratentorial primitive neuroectodermal tumors of the central nervous system
Gessi M, von Bueren A, Treszl A, Mühlen A, Hartmann W, Warmuth-Metz M, Rutkowski S, Pietsch T
NEURO-ONCOLOGY. 2014;16(7):924-932.

Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group
Gottardo N, Hansford J, McGlade J, Alvaro F, Ashley D, Bailey S, Baker D, Bourdeaut F, Cho Y, Clay M, Clifford S, Cohn R, Cole C, Dallas P, Downie P, Doz F, Ellison D, Endersby R, Fisher P, Hassall T, Heath J, Hii H, Jones D, Junckerstorff R, Kellie S, Kool M, Kotecha R, Lichter P, Laughton S, Lee S, McCowage G, Northcott P, Olson J, Packer R, Pfister S, Pietsch T, Pizer B, Pomeroy S, Remke M, Robinson G, Rutkowski S, Schoep T, Shelat A, Stewart C, Sullivan M, Taylor M, Wainwright B, Walwyn T, Weiss W, Williamson D, Gajjar A
ACTA NEUROPATHOL. 2014;127(2):189-201.

von Willebrand Factor Directly Interacts With DNA From Neutrophil Extracellular Traps
Grässle S, Huck V, Pappelbaum K, Gorzelanny C, Aponte-Santamaría C, Baldauf C, Gräter F, Schneppenheim R, Obser T, Schneider S
ARTERIOSCL THROM VAS. 2014;34(7):1382-1389.

SMARCA4-mutated atypical teratoid/rhabdoid tumors are associated with inherited germline alterations and poor prognosis
Hasselblatt M, Nagel I, Oyen F, Bartelheim K, Russell R, Schüller U, Junckerstorff R, Rosenblum M, Alassiri A, Rossi S, Schmid I, Gottardo N, Toledano H, Viscardi E, Balbin M, Witkowski L, Lu Q, Betts M, Foulkes W, Siebert R, Frühwald M, Schneppenheim R
ACTA NEUROPATHOL. 2014;128(3):453-6.

Inherited thrombotic thrombocytopenic purpura in children
Hassenpflug W, Budde U, Schneppenheim S, Schneppenheim R
SEMIN THROMB HEMOST. 2014;40(4):487-92.

Successful second ITI with factor IX and combined immunosuppressive therapy. A patient with severe haemophilia B and recurrence of a factor IX inhibitor
Holstein K, Schneppenheim R, Schrum J, Bokemeyer C, Langer F
HAMOSTASEOLOGIE. 2014;34 (4A):5-8.

Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing
Hovestadt V, Jones D, Picelli S, Wang W, Kool M, Northcott P, Sultan M, Stachurski K, Ryzhova M, Warnatz H, Ralser M, Brun S, Bunt J, Jäger N, Kleinheinz K, Erkek S, Weber U, Bartholomae C, von Kalle C, Lawerenz C, Eils J, Koster J, Versteeg R, Milde T, Witt O, Schmidt S, Wolf S, Pietsch T, Rutkowski S, Scheurlen W, Taylor M, Brors B, Felsberg J, Reifenberger G, Borkhardt A, Lehrach H, Wechsler-Reya R, Eils R, Yaspo M, Landgraf P, Korshunov A, Zapatka M, Radlwimmer B, Pfister S, Lichter P
NATURE. 2014;510(7506):537-541.

Hemophagocytic lymphohistiocytosis: A serious challenge for every physician
Janka-Schaub G
VET CLIN PATH. 2014;214(6):318-9.

Hemophagocytic syndromes - An update
Janka-Schaub G, Lehmberg K
BLOOD REV. 2014;28(4):135-142.

Quality of survival and growth in children and young adults in the PNET4 European controlled trial of hyperfractionated versus conventional radiation therapy for standard-risk medulloblastoma
Kennedy C, Bull K, Chevignard M, Culliford D, Dörr H, Doz F, Kortmann R, Lannering B, Massimino M, Navajas Gutiérrez A, Rutkowski S, Spoudeas H, Calaminus G
INT J RADIAT ONCOL. 2014;88(2):292-300.

Favorable outcome of patients affected by rhabdoid tumors due to rhabdoid tumor predisposition syndrome (RTPS)
Kordes U, Bartelheim K, Modena P, Massimino M, Biassoni V, Reinhard H, Hasselblatt M, Schneppenheim R, Frühwald M
PEDIATR BLOOD CANCER. 2014;61(5):919-21.

The PML domain of PML-RARα blocks senescence to promote leukemia
Korf K, Wodrich H, Haschke A, Ocampo C, Harder L, Gieseke F, Pollmann A, Dierck K, Prall S, Staege H, Ma H, Horstmann M, Evans R, Sternsdorf T
P NATL ACAD SCI USA. 2014;111(33):12133-8.

Platelet-free shear flow assay facilitates analysis of shear-dependent functions of VWF and ADAMTS13
Kraus E, Kraus K, Obser T, Oyen F, Klemm U, Schneppenheim R, Brehm M
THROMB RES. 2014;134(6):1285-1291.

Efficacious inhibition of Importin α/β-mediated nuclear import of human inositol phosphate multikinase
Kublun I, Ehm P, Brehm M, Nalaskowski M
BIOCHIMIE. 2014;102:117-23.

Characterisation of the p.A1461D mutation causing von Willebrand disease type 2B with severe thrombocytopenia, circulating giant platelets, and defective α-granule secretion
Langer F, Obser T, Oyen F, Spath B, Holstein K, Greinacher A, White J, Budde U, Bokemeyer C, Schneppenheim R
THROMB HAEMOSTASIS. 2014;111(4):777-779.

Treosulfan-based conditioning regimen for children and adolescents with hemophagocytic lymphohistiocytosis
Lehmberg K, Albert M, Beier R, Beutel K, Gruhn B, Kröger N, Meisel R, Schulz A, Stachel D, Woessmann W, Janka G, Müller I
HAEMATOLOGICA. 2014;99(1):180-4.

Determination of an appropriate cut-off value for ferritin in the diagnosis of hemophagocytic lymphohistiocytosis
Lehmberg K, McClain K, Janka-Schaub G, Allen C
PEDIATR BLOOD CANCER. 2014.

Brain iron quantification by MRI in mitochondrial membrane protein-associated neurodegeneration under iron-chelating therapy
Löbel U, Schweser F, Nickel M, Deistung A, Grosse R, Hagel C, Fiehler J, Schulz A, Hartig M, Reichenbach J, Kohlschütter A, Sedlacik J
Ann Clin Transl Neurol. 2014;1(12):1041-6.

Therapie traumatischer Pankreasverletzungen im Kindesalter
Maier S, Reinshagen K, Kähler G, Wessel L
ZBL CHIR. 2014;139(3):266-70.

PTEN microdeletions in T-cell acute lymphoblastic leukemia are caused by illegitimate RAG-mediated recombination events
Mendes R, Sarmento L, Canté-Barrett K, Zuurbier L, Buijs-Gladdines J, Póvoa V, Smits W, Abecasis M, Yunes J, Sonneveld E, Horstmann M, Pieters R, Barata J, Meijerink J
BLOOD. 2014;124(4):567-78.

Clinical features, treatment, and outcome of macrophage activation syndrome complicating systemic juvenile idiopathic Arthritis: a multinational, multicenter study of 362 patients
Minoia F, Davì S, Horne A, Demirkaya E, Bovis F, Li C, Lehmberg K, Weitzman S, Insalaco A, Wouters C, Shenoi S, Espada G, Ozen S, Anton J, Khubchandani R, Russo R, Pal P, Kasapcopur O, Miettunen P, Maritsi D, Merino R, Shakoory B, Alessio M, Chasnyk V, Sanner H, Gao Y, Huasong Z, Kitoh T, Avcin T, Fischbach M, Frosch M, Grom A, Huber A, Jelusic M, Sawhney S, Uziel Y, Ruperto N, Martini A, Cron R, Ravelli A
ARTHRITIS RHEUM-US. 2014;66(11):3160-9.

Loss of Smarc proteins impairs cerebellar development
Moreno N, Schmidt C, Ahlfeld J, Pöschl J, Dittmar S, Pfister S, Kool M, Kerl K, Schüller U
J NEUROSCI. 2014;34(40):13486-91.

Postponed is not canceled: role of craniospinal radiation therapy in the management of recurrent infant medulloblastoma--an experience from the HIT-REZ 1997 & 2005 studies
Müller K, Mynarek M, Zwiener I, Siegler N, Zimmermann M, Christiansen H, Budach W, Henke G, Warmuth-Metz M, Pietsch T, von Hoff K, von Bueren A, Bode U, Rutkowski S, Kortmann R, Fleischhack G, Tippelt S
INT J RADIAT ONCOL. 2014;88(5):1019-1024.

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
Northcott P, Lee C, Zichner T, Stütz A, Erkek S, Kawauchi D, Shih D, Hovestadt V, Zapatka M, Sturm D, Jones D, Kool M, Remke M, Cavalli F, Zuyderduyn S, Bader G, VandenBerg S, Esparza L, Ryzhova M, Wang W, Wittmann A, Stark S, Sieber L, Seker-Cin H, Linke L, Kratochwil F, Jäger N, Buchhalter I, Imbusch C, Zipprich G, Raeder B, Schmidt S, Diessl N, Wolf S, Wiemann S, Brors B, Lawerenz C, Eils J, Warnatz H, Risch T, Yaspo M, Weber U, Bartholomae C, von Kalle C, Turányi E, Hauser P, Sanden E, Darabi A, Siesjö P, Sterba J, Zitterbart K, Sumerauer D, van Sluis P, Versteeg R, Volckmann R, Koster J, Schuhmann M, Ebinger M, Grimes H, Robinson G, Gajjar A, Mynarek M, von Hoff K, Rutkowski S, Pietsch T, Scheurlen W, Felsberg J, Reifenberger G, Kulozik A, von Deimling A, Witt O, Eils R, Gilbertson R, Korshunov A, Taylor M, Lichter P, Korbel J, Wechsler-Reya R, Pfister S
NATURE. 2014;511(7510):428-434.

Hypertrophic olivary degeneration with gadolinium enhancement after posterior fossa surgery in a child with medulloblastoma
Nowak J, Alkonyi B, Rutkowski S, Homola G, Warmuth-Metz M
CHILD NERV SYST. 2014;30(5):959-62.

MRI Characteristics of Ependymoblastoma: Results from 22 Centrally Reviewed Cases
Nowak J, Seidel C, Berg F, Pietsch T, Friedrich C, von Hoff K, Rutkowski S, Warmuth-Metz M
AM J NEURORADIOL. 2014;35(10):1996-2001.

Ependymoblastoma of the brainstem: MRI findings and differential diagnosis
Nowak J, Seidel C, Pietsch T, Friedrich C, von Hoff K, Rutkowski S, Warmuth-Metz M
PEDIATR BLOOD CANCER. 2014;61(6):1132-1134.

Performance evaluation and multicentre study of a von Willebrand factor activity assay based on GPIb binding in the absence of ristocetin
Patzke J, Budde U, Huber A, Méndez A, Muth H, Obser T, Peerschke E, Wilkens M, Schneppenheim R
BLOOD COAGUL FIBRIN. 2014;25(8):860-870.

Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort
Pietsch T, Schmidt R, Remke M, Korshunov A, Hovestadt V, Jones D, Felsberg J, Kaulich K, Goschzik T, Kool M, Northcott P, von Hoff K, von Bueren A, Friedrich C, Mynarek M, Skladny H, Fleischhack G, Taylor M, Cremer F, Lichter P, Faldum A, Reifenberger G, Rutkowski S, Pfister S
ACTA NEUROPATHOL. 2014;128(1):137-149.

Wnt/β-catenin signaling inhibits the Shh pathway and impairs tumor growth in Shh-dependent medulloblastoma
Pöschl J, Bartels M, Ohli J, Bianchi E, Kuteykin-Teplyakov K, Grammel D, Ahlfeld J, Schüller U
ACTA NEUROPATHOL. 2014;127(4):605-7.

Genomic and transcriptomic analyses match medulloblastoma mouse models to their human counterparts
Pöschl J, Stark S, Neumann P, Gröbner S, Kawauchi D, Jones D, Northcott P, Lichter P, Pfister S, Kool M, Schüller U
ACTA NEUROPATHOL. 2014;128(1):123-36.

Choroid plexus carcinomas are characterized by complex chromosomal alterations related to patient age and prognosis
Ruland V, Hartung S, Kordes U, Wolff J, Paulus W, Hasselblatt M
GENE CHROMOSOME CANC. 2014;53(5):373-80.

Methylation of the hTERT promoter is frequent in choroid plexus tumors but not of independent prognostic value
Ruland V, Hartung S, Kordes U, Wolff J, Paulus W, Hasselblatt M
J NEURO-ONCOL. 2014;119(1):215-6.

Neuroonkologie
Rutkowski S, Hornung D, Kordes U, Kammler G, Hagel C, Löbel U, Ebinger M, Rössler J, Resch A, Linhart D
2014. Neuropädiatrie - Evidenzbasierte Therapie. Korinthenberg R, Panteliadis C, Hagel C (Hrsg.). 2. Aufl. München: Elsevier, .

Postmortem 31P magnetic resonance spectroscopy of the skeletal muscle: α-ATP/Pi ratio as a forensic tool?
Schmidt T, Wang Z, Keller S, Heinemann A, Acar S, Graessner J, Schoennagel B, Adam G, Fischer R, Yamamura J
FORENSIC SCI INT. 2014;242:172-6.

Signal-peptide-peptidase-like 2a is required for CD74 intramembrane proteolysis in human B cells
Schneppenheim J, Hüttl S, Kruchen A, Fluhrer R, Müller I, Saftig P, Schneppenheim R, Martin C, Schröder B
BIOCHEM BIOPH RES CO. 2014;451(1):48-53.

Fetal blood flow velocimetry by phase-contrast MRI using a new triggering method and comparison with Doppler ultrasound in a sheep model: a pilot study
Schoennagel B, Remus C, Yamamura J, Kording F, de Sousa M, Hecher K, Fischer R, Ueberle F, Boehme M, Adam G, Kooijman H, Wedegärtner U
MAGN RESON MATER PHY. 2014;27(3):237-44.

Feasibility of intensive multimodal therapy in infants affected by rhabdoid tumors - experience of the EU-RHAB registry
Seeringer A, Bartelheim K, Kerl K, Hasselblatt M, Leuschner I, Rutkowski S, Timmermann B, Kortmann R, Koscielniak E, Schneppenheim R, Warmuth-Metz M, Gerß J, Siebert R, Graf N, Boos J, Frühwald M
KLIN PADIATR. 2014;226(3):143-148.

Synchronous congenital malignant rhabdoid tumor of the orbit and atypical teratoid/rhabdoid tumor--feasibility and efficacy of multimodal therapy in a long-term survivor
Seeringer A, Reinhard H, Hasselblatt M, Schneppenheim R, Siebert R, Bartelheim K, Leuschner I, Frühwald M
CANCER GENET-NY. 2014;207(9):429-33.

Cytogenetic prognostication within medulloblastoma subgroups
Shih D, Northcott P, Remke M, Korshunov A, Ramaswamy V, Kool M, Luu B, Yao Y, Wang X, Dubuc A, Garzia L, Peacock J, Mack S, Wu X, Rolider A, Morrissy A, Cavalli F, Jones D, Zitterbart K, Faria C, Schüller U, Kren L, Kumabe T, Tominaga T, Shin Ra Y, Garami M, Hauser P, Chan J, Robinson S, Bognár L, Klekner A, Saad A, Liau L, Albrecht S, Fontebasso A, Cinalli G, De Antonellis P, Zollo M, Cooper M, Thompson R, Bailey S, Lindsey J, Di Rocco C, Massimi L, Michiels E, Scherer S, Phillips J, Gupta N, Fan X, Muraszko K, Vibhakar R, Eberhart C, Fouladi M, Lach B, Jung S, Wechsler-Reya R, Fèvre-Montange M, Jouvet A, Jabado N, Pollack I, Weiss W, Lee J, Cho B, Kim S, Wang K, Leonard J, Rubin J, de Torres C, Lavarino C, Mora J, Cho Y, Tabori U, Olson J, Gajjar A, Packer R, Rutkowski S, Pomeroy S, French P, Kloosterhof N, Kros J, Van Meir E, Clifford S, Bourdeaut F, Delattre O, Doz F, Hawkins C, Malkin D, Grajkowska W, Perek-Polnik M, Bouffet E, Rutka J, Pfister S, Taylor M
J CLIN ONCOL. 2014;32(9):886-896.

Update on von Willebrand factor multimers: focus on high-molecular-weight multimers and their role in hemostasis
Stockschlaeder M, Schneppenheim R, Budde U
BLOOD COAGUL FIBRIN. 2014;25(3):206-16.

Therapie hereditärer Thrombozytopathien. Interdisziplinäre S2K-Leitlinie der Ständigen Kommission Pädiatrie der Gesellschaft für Thrombose- und Hämostaseforschung e. V
Streif W, Knöfler R, Eberl W, Andres O, Bakchoul T, Bergmann F, Beutel K, Dittmer R, Gehrisch S, Gottstein S, Halimeh S, Haselböck J, Hassenpflug W, Heine S, Holzhauer S, King S, Kirchmaier C, Krause M, Kreuz W, Lösche W, Mahnel R, Maurer M, Nimtz-Talaska A, Olivieri M, Rott H, Schambeck C, Schedel A, Schilling F, Schmugge M, Schneppenheim R, Scholz U, Scholz T, Schulze H, Siegemund A, Strauß G, Sykora K, Wermes C, Wiegering V, Wieland I, Zieger B, Zotz R
HAMOSTASEOLOGIE. 2014;34(4):269-75.

Significantly increased CD70 up regulation on TEL-AML positive B cell precursor acute lymphoblastic leukemia cells following CD40 stimulation
Troeger A, Glouchkova L, Ackermann B, Escherich G, Hanenberg H, Janka G, Roettgers S, Göbel U, Dilloo D
KLIN PADIATR. 2014;226(6-7):332-337.

Interference with pre-B-cell receptor signaling offers a therapeutic option for TCF3-rearranged childhood acute lymphoblastic leukemia
van der Veer A, van der Velden V, Willemse M, Hoogeveen P, Petricoin E, Beverloo H, Escherich G, Horstmann M, Pieters R, den Boer M
BLOOD CANCER J. 2014;4:e181.

Identifying molecular markers for the sensitive detection of residual atypical teratoid rhabdoid tumor cells
Vu-Han T, Frühwald M, Hasselblatt M, Kerl K, Nagel I, Obser T, Oyen F, Siebert R, Schneppenheim R
CANCER GENET-NY. 2014;207(9):390-397.

Subgroup-specific localization of human medulloblastoma based on pre-operative MRI
Wefers A, Warmuth-Metz M, Pöschl J, von Bueren A, Monoranu C, Seelos K, Peraud A, Tonn J, Koch A, Pietsch T, Herold-Mende C, Mawrin C, Schouten-van Meeteren A, van Vuurden D, von Hoff K, Rutkowski S, Pfister S, Kool M, Schüller U
ACTA NEUROPATHOL. 2014;127(6):931-3.

WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma
Zhukova N, Ramaswamy V, Remke M, Martin D, Castelo-Branco P, Zhang C, Fraser M, Tse K, Poon R, Shih D, Baskin B, Ray P, Bouffet E, Dirks P, von Bueren A, Pfaff E, Korshunov A, Jones D, Northcott P, Kool M, Pugh T, Pomeroy S, Cho Y, Pietsch T, Gessi M, Rutkowski S, Bognár L, Cho B, Eberhart C, Conter C, Fouladi M, French P, Grajkowska W, Gupta N, Hauser P, Jabado N, Vasiljevic A, Jung S, Kim S, Klekner A, Kumabe T, Lach B, Leonard J, Liau L, Massimi L, Pollack I, Ra Y, Rubin J, Van Meir E, Wang K, Weiss W, Zitterbart K, Bristow R, Alman B, Hawkins C, Malkin D, Clifford S, Pfister S, Taylor M, Tabori U
Acta Neuropathol Comm. 2014;2:174.

Immature MEF2C-dysregulated T-cell leukemia patients have an early T-cell precursor acute lymphoblastic leukemia gene signature and typically have non-rearranged T-cell receptors
Zuurbier L, Gutierrez A, Mullighan C, Canté-Barrett K, Gevaert A, de Rooi J, Li Y, Smits W, Buijs-Gladdines J, Sonneveld E, Look A, Horstmann M, Pieters R, Meijerink J
HAEMATOLOGICA. 2014;99(1):94-102.

2013

Phenotypic and molecular characterisation of type 3 von Willebrand disease in a cohort of Indian patients
Ahmad F, Budde U, Jan R, Oyen F, Kannan M, Saxena R, Schneppenheim R
THROMB HAEMOSTASIS. 2013;109(4):652-60.

Characterisation of mutations and molecular studies of type 2 von Willebrand disease.
Ahmad F, Jan R, Kannan M, Obser T, Hassan M, Oyen F, Budde U, Saxena R, Schneppenheim R
THROMB HAEMOSTASIS. 2013;109(1):39-46.

PGK1 as predictor of CXCR4 expression, bone marrow metastases and survival in neuroblastoma
Ameis H, Drenckhan A, Loga K, Escherich G, Wenke K, Izbicki J, Reinshagen K, Gros S
PLOS ONE. 2013;8(12):e83701.

Allo-SCT using BU, CY and melphalan for children with AML in second CR
Beier R, Albert M, Bader P, Borkhardt A, Creutzig U, Eyrich M, Ehlert K, Gruhn B, Greil J, Handgretinger R, Holter W, Klingebiel T, Kremens B, Lang P, Mauz-Körholz C, Meisel R, Müller I, Peters C, Reinhardt D, Sedlacek P, Schulz A, Schuster F, Schrauder A, Strahm B, Sykora K, Wössmann W, Zimmermann M, Sauer M
BONE MARROW TRANSPL. 2013;48(5):651-6.

Primary intracranial soft tissue sarcoma in children and adolescents: a cooperative analysis of the European CWS and HIT study groups
Benesch M, von Bueren A, Dantonello T, von Hoff K, Pietsch T, Leuschner I, Claviez A, Bierbach U, Kropshofer G, Korinthenberg R, Graf N, Suttorp M, Kortmann R, Friedrich C, von der Weid N, Kaatsch P, Klingebiel T, Koscielniak E, Rutkowski S
J NEURO-ONCOL. 2013;111(3):337-345.

Fulminant Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis.
Bohne S, Kentouche K, Petersen I, Fritzenwanger M, Pletz M, Lehmberg K, Paul L, Guntinas-Lichius O
LARYNGOSCOPE. 2013;123(2):362-365.

Incidence and prognostic relevance of genetic variations in T-cell lymphoblastic lymphoma in childhood and adolescence
Bonn B, Rohde M, Zimmermann M, Krieger D, Oschlies I, Niggli F, Wrobel G, Attarbaschi A, Escherich G, Klapper W, Reiter A, Burkhardt B
BLOOD. 2013;121(16):3153-60.

Syntaxin 11 is required for NK and CD8⁺ T-cell cytotoxicity and neutrophil degranulation.
D'Orlando O, Zhao F, Kasper B, Orinska Z, Müller J, Hermans-Borgmeyer I, Griffiths G, Zur Stadt U, Bulfone-Paus S
EUR J IMMUNOL. 2013;43(1):194-208.

Use of allogeneic hematopoietic stem-cell transplantation based on minimal residual disease response improves outcomes for children with relapsed acute lymphoblastic leukemia in the intermediate-risk group
Eckert C, Henze G, Seeger K, Hagedorn N, Mann G, Panzer-Grümayer R, Peters C, Klingebiel T, Borkhardt A, Schrappe M, Schrauder A, Escherich G, Sramkova L, Niggli F, Hitzler J, von Stackelberg A
J CLIN ONCOL. 2013;31(21):2736-42.

Minimal residual disease after induction is the strongest predictor of prognosis in intermediate risk relapsed acute lymphoblastic leukaemia - long-term results of trial ALL-REZ BFM P95/96.
Eckert C, von Stackelberg A, Seeger K, Groeneveld T, Peters C, Klingebiel T, Borkhardt A, Schrappe M, Escherich G, Henze G
EUR J CANCER. 2013;49(6):1346-1355.

VWF propeptide and ratios between VWF, VWF propeptide, and FVIII in the characterization of type 1 von Willebrand disease
Eikenboom J, Federici A, Dirven R, Castaman G, Rodeghiero F, Budde U, Schneppenheim R, Batlle J, Canciani M, Goudemand J, Peake I, Goodeve A
BLOOD. 2013;121(12):2336-9.

Identification of a homozygous Cys410Ser mutation in the von Willebrand factor D2 domain causing type 2A(IIC) von Willebrand disease phenotype in an Iranian patient
Enayat M, Ravanbod S, Rassoulzadegan M, Jazebi M, Ala F, Budde U, Schneppenheim S, Obser T, Schneppenheim R
HAEMOPHILIA. 2013;19(4):e261-4.

Doxorubicin or daunorubicin given upfront in a therapeutic window are equally effective in children with newly diagnosed acute lymphoblastic leukemia. A randomized comparison in trial CoALL 07-03.
Escherich G, Zimmermann M, Janka-Schaub G
PEDIATR BLOOD CANCER. 2013;60(2):254-257.

Clofarabine in combination with pegylated asparaginase in the frontline treatment of childhood acute lymphoblastic leukaemia: a feasibility report from the CoALL 08-09 trial
Escherich G, Zur Stadt U, Zimmermann M, Horstmann M
BRIT J HAEMATOL. 2013;163(2):240-7.

Treatment of young children with CNS-primitive neuroectodermal tumors/pineoblastomas in the prospective multicenter trial HIT 2000 using different chemotherapy regimens and radiotherapy.
Friedrich C, von Bueren A, von Hoff K, Gerber N, Ottensmeier H, Deinlein F, Benesch M, Kwiecien R, Pietsch T, Warmuth-Metz M, Faldum A, Kuehl J, Kortmann R, Rutkowski S
NEURO-ONCOLOGY. 2013;15(2):224-234.

Treatment of adult nonmetastatic medulloblastoma patients according to the paediatric HIT 2000 protocol: a prospective observational multicentre study
Friedrich C, von Bueren A, von Hoff K, Kwiecien R, Pietsch T, Warmuth-Metz M, Hau P, Deinlein F, Kuehl J, Kortmann R, Rutkowski S
EUR J CANCER. 2013;49(4):893-903.

Distinct role of von Willebrand factor triplet bands in glycoprotein Ib-dependent platelet adhesion and thrombus formation under flow
Fuchs B, de Witt S, Solecka B, Kröning M, Obser T, Cosemans J, Schneppenheim R, Heemskerk J, Kannicht C
SEMIN THROMB HEMOST. 2013;39(3):306-14.

Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation
Gieseke F, Kruchen A, Tzaribachev N, Bentzien F, Dominici M, Müller I
EUR J IMMUNOL. 2013;43(10):2741-9.

Syntaxin binding mechanism and disease-causing mutations in Munc18-2
Hackmann Y, Graham S, Ehl S, Höning S, Lehmberg K, Aricò M, Owen D, Griffiths G
P NATL ACAD SCI USA. 2013;110(47):E4482-91.

Supra- and infratentorial pediatric ependymomas differ significantly in NeuN, p75 and GFAP expression
Hagel C, Treszl A, Fehlert J, Harder J, von Haxthausen F, Kern M, von Bueren A, Kordes U
J NEURO-ONCOL. 2013;112(2):191-7.

Aberrant ZNF423 impedes B cell differentiation and is linked to adverse outcome of ETV6-RUNX1 negative B precursor acute lymphoblastic leukemia
Harder L, Eschenburg G, Zech A, Kriebitzsch N, Otto B, Streichert T, Behlich A, Dierck K, Klingler B, Hansen A, Stanulla M, Zimmermann M, Kremmer E, Stocking C, Horstmann M
J EXP MED. 2013;210(11):2289-304.

Inhibiting Polo-like kinase 1 causes growth reduction and apoptosis in pediatric acute lymphoblastic leukemia cells
Hartsink-Segers S, Exalto C, Allen M, Williamson D, Clifford S, Horstmann M, Caron H, Pieters R, Den Boer M
HAEMATOLOGICA. 2013;98(10):1539-46.

Fatal neurological side-effects with necrosis of spinal cord following nelarabine treatment in a child with relapsed T-cell acute lymphoblastic leukemia
Hartz B, Löbel U, Hagel C, Escherich G
AM J HEMATOL. 2013;88(12):1096-7.

High-resolution genomic analysis suggests the absence of recurrent genomic alterations other than SMARCB1 aberrations in atypical teratoid/rhabdoid tumors.
Hasselblatt M, Isken S, Linge A, Eikmeier K, Jeibmann A, Oyen F, Nagel I, Richter J, Bartelheim K, Kordes U, Schneppenheim R, Frühwald M, Siebert R, Paulus W
GENE CHROMOSOME CANC. 2013;52(2):185-190.

Activated human hepatic stellate cells induce myeloid derived suppressor cells from peripheral blood monocytes in a CD44-dependent fashion
Höchst B, Schildberg F, Sauerborn P, Gäbel Y, Gevensleben H, Goltz D, Heukamp L, Türler A, Ballmaier M, Gieseke F, Müller I, Kalff J, Kurts C, Knolle P, Diehl L
J HEPATOL. 2013;59(3):528-35.

Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays
Hovestadt V, Remke M, Kool M, Pietsch T, Northcott P, Fischer R, Cavalli F, Ramaswamy V, Zapatka M, Reifenberger G, Rutkowski S, Schick M, Bewerunge-Hudler M, Korshunov A, Lichter P, Taylor M, Pfister S, Jones D
ACTA NEUROPATHOL. 2013;125(6):913-6.

Hemophagocytic lymphohistiocytosis - pathogenesis and treatment
Janka-Schaub G, Lehmberg K
Hematology Am Soc Hematol Educ Program. 2013;2013:605-11.

The risk of hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type 2
Jessen B, Bode S, Ammann S, Chakravorty S, Davies G, Diestelhorst J, Frei-Jones M, Gahl W, Gochuico B, Griese M, Griffiths G, Janka-Schaub G, Klein C, Kögl T, Kurnik K, Lehmberg K, Maul-Pavicic A, Mumford A, Pace D, Parvaneh N, Rezaei N, de Saint Basile G, Schmitt-Graeff A, Schwarz K, Karasu G, Zieger B, zur Stadt U, Aichele P, Ehl S
BLOOD. 2013;121(15):2943-51.

Phenotypic and genotypic characterization of 10 Finnish patients with von Willebrand disease type 3: discovery of two main mutations
Jokela V, Lassila R, Szanto T, Joutsi-Korhonen L, Armstrong E, Oyen F, Schneppenheim S, Schneppenheim R
HAEMOPHILIA. 2013;19(6):e344-8.

Pregnancy in Upshaw-Schulman syndrome
Kentouche K, Voigt A, Schleussner E, Schneppenheim R, Budde U, Beck J, Stefańska-Windyga E, Windyga J
HAMOSTASEOLOGIE. 2013;33(2):144-8.

Hemophagocytic lymphohistiocytosis in syntaxin-11-deficient mice: T-cell exhaustion limits fatal disease
Kögl T, Müller J, Jessen B, Schmitt-Graeff A, Janka-Schaub G, Ehl S, zur Stadt U, Aichele P
BLOOD. 2013;121(4):604-13.

Juvenile metachromatic leukodystrophy 10 years post transplant compared with a non-transplanted cohort
Krägeloh-Mann I, Groeschel S, Kehrer C, Opherk K, Nägele T, Handgretinger R, Müller I
BONE MARROW TRANSPL. 2013;48(3):369-75.

Denosumab
Lange T, Stehling C, Fröhlich B, Klingenhöfer M, Kunkel P, Schneppenheim R, Escherich G, Gosheger G, Hardes J, Jürgens H, Schulte T
EUR SPINE J. 2013;22(6):1417-22.

Diagnostic evaluation of patients with suspected haemophagocytic lymphohistiocytosis.
Lehmberg K, Ehl S
BRIT J HAEMATOL. 2013;160(3):275-287.

Administration of recombinant erythropoietin alone does not improve the phenotype in iron refractory iron deficiency anemia patients.
Lehmberg K, Grosse R, Muckenthaler M, Altamura S, Nielsen P, Schmid H, Graubner U, Oyen F, Zeller W, Schneppenheim R, Janka-Schaub G
ANN HEMATOL. 2013;92(3):387-394.

Differentiating macrophage activation syndrome in systemic juvenile idiopathic arthritis from other forms of hemophagocytic lymphohistiocytosis
Lehmberg K, Pink I, zu Eulenburg C, Beutel K, Maul-Pavicic A, Janka-Schaub G
J PEDIATR-US. 2013;162(6):1245-51.

Exponential size distribution of von Willebrand factor
Lippok S, Obser T, Müller J, Stierle V, Benoit M, Budde U, Schneppenheim R, Rädler J
BIOPHYS J. 2013;105(5):1208-16.

Prophylactic efficacy and pharmacokinetically guided dosing of a von Willebrand factor/factor VIII concentrate in adults and children with von Willebrand's disease undergoing elective surgery
Mannuccio Mannucci P, Kyrle P, Schulman S, Di Paola J, Schneppenheim R, Cox Gill J
Haematol Blood Transfus. 2013;11(4):533-40.

Hereditary thrombotic thrombocytopenic purpura and the hereditary TTP registry
Mansouri Taleghani M, von Krogh A, Fujimura Y, George J, Hrachovinová I, Knöbl P, Quist-Paulsen P, Schneppenheim R, Lämmle B, Kremer Hovinga J
HAMOSTASEOLOGIE. 2013;33(2):138-43.

Allogeneic hematopoietic cell transplantation for XIAP deficiency: an international survey reveals poor outcomes.
Marsh R, Rao K, Satwani P, Lehmberg K, Müller I, Li D, Kim M, Fischer A, Latour S, Sedlacek P, Barlogis V, Hamamoto K, Kanegane H, Milanovich S, Margolis D, Dimmock D, Casper J, Douglas D, Amrolia P, Veys P, Kumar A, Jordan M, Bleesing J, Filipovich A
BLOOD. 2013;121(6):877-883.

Refinement of IKZF1 recombination hotspots in pediatric BCP-ALL patients.
Meyer C, Zur Stadt U, Escherich G, Hofmann J, Binato R, Barbosa T, Emerenciano M, Pombo-de-Oliveira M, Horstmann M, Marschalek R
Am J Blood Res. 2013;3(2):165-173.

Outcomes of treatment for relapsed acute lymphoblastic leukaemia in children with Down syndrome
Meyr F, Escherich G, Mann G, Klingebiel T, Kulozik A, Rossig C, Schrappe M, Henze G, von Stackelberg A, Hitzler J
BRIT J HAEMATOL. 2013;162(1):98-106.

What's in a name? Intracranial peripheral primitive neuroectodermal tumors and CNS primitive neuroectodermal tumors are not the same
Müller K, Diez B, Muggeri A, Pietsch T, Friedrich C, Rutkowski S, von Hoff K, von Bueren A, Zwiener I, Bruns F
STRAHLENTHER ONKOL. 2013;189(5):372-9.

Outcome of allogeneic SCT in patients with chronic myeloid leukemia in the era of tyrosine kinase inhibitor therapy.
Oyekunle A, Zander A, Binder M, Ayuketang F, Zabelina T, Christopeit M, Stübig T, Alchalby H, Schafhausen P, Lellek H, Wolschke C, Müller I, Bacher U, Kröger N
ANN HEMATOL. 2013;92(4):487-496.

Ultralarge von Willebrand factor fibers mediate luminal Staphylococcus aureus adhesion to an intact endothelial cell layer under shear stress
Pappelbaum K, Gorzelanny C, Grässle S, Suckau J, Laschke M, Bischoff M, Bauer C, Schorpp-Kistner M, Weidenmaier C, Schneppenheim R, Obser T, Sinha B, Schneider S
CIRCULATION. 2013;128(1):50-9.

Constitutive activation of β-catenin in neural progenitors results in disrupted proliferation and migration of neurons within the central nervous system
Pöschl J, Grammel D, Dorostkar M, Kretzschmar H, Schüller U
DEV BIOL. 2013;374(2):319-32.

Somatostatin receptor subtype 2 (sst₂) is a potential prognostic marker and a therapeutic target in medulloblastoma
Remke M, Hering E, Gerber N, Kool M, Sturm D, Rickert C, Gerß J, Schulz S, Hielscher T, Hasselblatt M, Jeibmann A, Hans V, Ramaswamy V, Taylor M, Pietsch T, Rutkowski S, Korshunov A, Monoranu C, Frühwald M
CHILD NERV SYST. 2013;29(8):1253-62.

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma
Remke M, Ramaswamy V, Peacock J, Shih D, Koelsche C, Northcott P, Hill N, Cavalli F, Kool M, Wang X, Mack S, Barszczyk M, Morrissy A, Wu X, Agnihotri S, Luu B, Jones D, Garzia L, Dubuc A, Zhukova N, Vanner R, Kros J, French P, Van Meir E, Vibhakar R, Zitterbart K, Chan J, Bognár L, Klekner A, Lach B, Jung S, Saad A, Liau L, Albrecht S, Zollo M, Cooper M, Thompson R, Delattre O, Bourdeaut F, Doz F, Garami M, Hauser P, Carlotti C, Van Meter T, Massimi L, Fults D, Pomeroy S, Kumabe T, Ra Y, Leonard J, Elbabaa S, Mora J, Rubin J, Cho Y, McLendon R, Bigner D, Eberhart C, Fouladi M, Wechsler-Reya R, Faria C, Croul S, Huang A, Bouffet E, Hawkins C, Dirks P, Weiss W, Schüller U, Pollack I, Rutkowski S, Meyronet D, Jouvet A, Fèvre-Montange M, Jabado N, Perek-Polnik M, Grajkowska W, Kim S, Rutka J, Malkin D, Tabori U, Pfister S, Korshunov A, von Deimling A, Taylor M
ACTA NEUROPATHOL. 2013;126(6):917-29.

Sequential decisions on FAS sequencing guided by biomarkers in patients with lymphoproliferation and autoimmune cytopenia
Rensing-Ehl A, Janda A, Lorenz M, Gladstone B, Fuchs I, Abinun M, Albert M, Butler K, Cant A, Cseh A, Ebinger M, Goldacker S, Hambleton S, Hebart H, Houet L, Kentouche K, Kühnle I, Lehmberg K, Mejstrikova E, Niemeyer C, Minkov M, Neth O, Dückers G, Owens S, Rösler J, Schilling F, Schuster V, Seidel M, Smisek P, Sukova M, Svec P, Wiesel T, Gathmann B, Schwarz K, Vach W, Ehl S, Speckmann C
HAEMATOLOGICA. 2013;98(12):1948-55.

Systematic review and meta-analysis of randomized trials of central nervous system directed therapy for childhood acute lymphoblastic leukemia
Richards S, Pui C, Gayon P
PEDIATR BLOOD CANCER. 2013;60(2):185-95.

Effective childhood cancer Treatment: the impact of large scale clinical trials in Germany and Austria
Rossig C, Juergens H, Schrappe M, Moericke A, Henze G, von Stackelberg A, Reinhardt D, Burkhardt B, Woessmann W, Zimmermann M, Gadner H, Mann G, Schellong G, Mauz-Koerholz C, Dirksen U, Bielack S, Berthold F, Graf N, Rutkowski S, Calaminus G, Kaatsch P, Creutzig U
PEDIATR BLOOD CANCER. 2013;60(10):1574-81.

A very rare cancer in Down Syndrome: medulloblastoma. Epidemiological data from 13 countries
Satgé D, Stiller C, Rutkowski S, von Bueren A, Lacour B, Sommelet D, Nishi M, Massimino M, Garré M, Moreno F, Hasle H, Jakab Z, Greenberg M, von der Weid N, Kuehni C, Zurriaga O, Vicente M, Peris-Bonet R, Benesch M, Vekemans M, Sullivan S, Rickert C
J NEURO-ONCOL. 2013;112(1):107-14.

Second malignant neoplasms after treatment of childhood acute lymphoblastic leukemia
Schmiegelow K, Levinsen M, Attarbaschi A, Baruchel A, Devidas M, Escherich G, Gibson B, Heydrich C, Horibe K, Ishida Y, Liang D, Locatelli F, Michel G, Pieters R, Piette C, Pui C, Raimondi S, Silverman L, Stanulla M, Stark B, Winick N, Valsecchi M
J CLIN ONCOL. 2013;31(19):2469-76.

BOLD MRI in the brain of fetal sheep at 3T during experimental hypoxia
Schoennagel B, Yamamura J, Fischer R, de Sousa M, Weyhmiller M, Birkelbach M, Kooijman H, Adam G, Wedegärtner U
J MAGN RESON IMAGING. 2013.

Eisenquantifizierung mittels MRT bei Eisenüberladung
Schönnagel B, Fischer R, Nielsen P, Grosse R, Adam G, Yamamura J
ROFO-FORTSCHR RONTG. 2013;185(7):621-7.

X-linked inhibitor of apoptosis (XIAP) deficiency: the spectrum of presenting manifestations beyond hemophagocytic lymphohistiocytosis
Speckmann C, Lehmberg K, Albert M, Damgaard R, Fritsch M, Gyrd-Hansen M, Rensing-Ehl A, Vraetz T, Grimbacher B, Salzer U, Fuchs I, Ufheil H, Belohradsky B, Hassan A, Cale C, Elawad M, Strahm B, Schibli S, Lauten M, Kohl M, Meerpohl J, Rodeck B, Kolb R, Eberl W, Soerensen J, von Bernuth H, Lorenz M, Schwarz K, zur Stadt U, Ehl S
CLIN IMMUNOL. 2013;149(1):133-41.

Pediatric Acute Lymphoblastic Leukemia: Efficacy and safety of recombinant E. coli-asparaginase in infants (less than one year of age) with acute lymphoblastic leukemia
van der Sluis I, Möricke A, Escherich G, von Stackelberg A, Holter W, Klingebiel T, Flotho C, Legien S, Tissing W, Bierings M, Guimbal-Schmolck C, Pichlmeier U, Kühnel H, Pieters R
HAEMATOLOGICA. 2013;98(11):1697-701.

Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL
van der Veer A, Waanders E, Pieters R, Willemse M, Van Reijmersdal S, Russell L, Harrison C, Evans W, van der Velden V, Hoogerbrugge P, Van Leeuwen F, Escherich G, Horstmann M, Mohammadi Khankahdani L, Rizopoulos D, De Groot-Kruseman H, Sonneveld E, Kuiper R, Den Boer M
BLOOD. 2013;122(15):2622-9.

Clinical phenotype and functional analysis of a rare XIAP/BIRC4 mutation
Vieth S, Ammann S, Schwarz K, Härtel C, Schultz C, Lehmberg K, Lauten M
KLIN PADIATR. 2013;225(6):343-6.

Infantile malignant brain tumors
von Hoff K, Rutkowski S
2013. Tumors of the pediatric central nervous system. Keating R, Tait Goodrich J, Packer R (Hrsg.). 2.. Aufl. New York: Georg Thieme Verlag , .

Challenges with defining response to antitumor agents in pediatric neuro-oncology: a report from the response assessment in pediatric neuro-oncology (RAPNO) working group
Warren K, Poussaint T, Vezina G, Hargrave D, Packer R, Goldman S, Wen P, Pollack I, Zurakowski D, Kun L, Prados M, Rutkowski S, Kieran M
PEDIATR BLOOD CANCER. 2013;60(9):1397-401.

Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma
Zhukova N, Ramaswamy V, Remke M, Pfaff E, Shih D, Martin D, Castelo-Branco P, Baskin B, Ray P, Bouffet E, von Bueren A, Jones D, Northcott P, Kool M, Sturm D, Pugh T, Pomeroy S, Cho Y, Pietsch T, Gessi M, Rutkowski S, Bognar L, Klekner A, Cho B, Kim S, Wang K, Eberhart C, Fevre-Montange M, Fouladi M, French P, Kros M, Grajkowska W, Gupta N, Weiss W, Hauser P, Jabado N, Jouvet A, Jung S, Kumabe T, Lach B, Leonard J, Rubin J, Liau L, Massimi L, Pollack I, Shin Ra Y, Van Meir E, Zitterbart K, Schüller U, Hill R, Lindsey J, Schwalbe E, Bailey S, Ellison D, Hawkins C, Malkin D, Clifford S, Korshunov A, Pfister S, Taylor M, Tabori U
J CLIN ONCOL. 2013;31(23):2927-35.

2012

ALDH1A1 is a marker of astrocytic differentiation during brain development and correlates with better survival in glioblastoma patients
Adam S, Schnell O, Pöschl J, Eigenbrod S, Kretzschmar H, Tonn J, Schüller U
BRAIN PATHOL. 2012;22(6):788-97.

Imatinib after induction for treatment of children and adolescents with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (EsPhALL): a randomised, open-label, intergroup study.
Biondi A, Schrappe M, Paola D, Castor A, Lucchini G, Gandemer V, Pieters R, Stary J, Escherich G, Campbell M, Li C, Vora A, Aricò M, Röttgers S, Saha V, Valsecchi M
LANCET ONCOL. 2012;13(9):936-945.

Recent advances in the diagnosis and treatment of hemophagocytic lymphohistiocytosis.
Bode S, Lehmberg K, Maul-Pavicic A, Vraetz T, Janka-Schaub G, Zur Stadt U, Ehl S
ARTHRITIS RES THER. 2012;14(3):213.

Leukemia-associated mutations in SHIP1 inhibit its enzymatic activity, interaction with the GM-CSF receptor and Grb2, and its ability to inactivate PI3K/AKT signaling.
Brauer H, Strauss J, Wegner W, Müller-Tidow C, Horstmann M, Jücker M
CELL SIGNAL. 2012;24(11):2095-2101.

A prospective evaluation of degranulation assays in the rapid diagnosis of familial hemophagocytic syndromes.
Bryceson Y, Pende D, Maul-Pavicic A, Gilmour K, Ufheil H, Vraetz T, Chiang S, Marcenaro S, Meazza R, Bondzio I, Walshe D, Janka-Schaub G, Lehmberg K, Beutel K, Zur Stadt U, Binder N, Arico M, Moretta L, Henter J, Ehl S
BLOOD. 2012;119(12):2754-2763.

Reduced von Willebrand factor secretion is associated with loss of Weibel-Palade body formation.
Castaman G, Giacomelli S, Jacobi P, Obser T, Budde U, Rodeghiero F, Schneppenheim R, Haberichter S
J THROMB HAEMOST. 2012;10(5):951-958.

Defibrotide for prophylaxis of hepatic veno-occlusive disease in paediatric haemopoietic stem-cell transplantation: an open-label, phase 3, randomised controlled trial.
Corbacioglu S, Cesaro S, Faraci M, Valteau-Couanet D, Gruhn B, Rovelli A, Boelens J, Hewitt A, Schrum J, Schulz A, Müller I, Stein J, Wynn R, Greil J, Sykora K, Matthes-Martin S, Führer M, O'Meara A, Toporski J, Sedlacek P, Schlegel P, Ehlert K, Fasth A, Winiarski J, Arvidson J, Mauz-Körholz C, Ozsahin H, Schrauder A, Bader P, Massaro J, D'Agostino R, Hoyle M, Iacobelli M, Debatin K, Peters C, Dini G
LANCET. 2012;379(9823):1301-1309.

Caspofungin as antifungal prophylaxis in pediatric patients undergoing allogeneic hematopoietic stem cell transplantation: a retrospective analysis.
Döring M, Hartmann U, Erbacher A, Lang P, Handgretinger R, Müller I
BMC INFECT DIS. 2012;12:151.

Analysis of posaconazole as oral antifungal prophylaxis in pediatric patients under 12 years of age following allogeneic stem cell transplantation.
Döring M, Müller C, Johann P, Erbacher A, Kimmig A, Schwarze C, Lang P, Handgretinger R, Müller I
BMC INFECT DIS. 2012;12:263.

Eradication of pulmonary aspergillosis in an adolescent patient undergoing three allogeneic stem cell transplantations for acute lymphoblastic leukemia.
Döring M, Zierl A, Mezger M, Lang P, Handgretinger R, Müller I
Case Rep Transplant. 2012;2012:672923.

Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia.
Ellinghaus E, Stanulla M, Richter G, Ellinghaus D, Te Kronnie G, Cario G, Cazzaniga G, Horstmann M, Panzer Grümayer R, Cavé H, Trka J, Cinek O, Teigler-Schlegel A, ElSharawy A, Häsler R, Nebel A, Meissner B, Bartram T, Lescai F, Franceschi C, Giordan M, Nürnberg P, Heinzow B, Zimmermann M, Schreiber S, Schrappe M, Franke A
LEUKEMIA. 2012;26(5):902-909.

Proper cerebellar development requires expression of β1-integrin in Bergmann glia, but not in granule neurons.
Frick A, Grammel D, Schmidt F, Pöschl J, Priller M, Pagella P, von Bueren A, André O, Peraud A, Tonn J, Rutkowski S, Rutkowski S, Kretzschmar H, Schüller U
GLIA. 2012;60(5):820-832.

A long duration of the prediagnostic symptomatic interval is not associated with an unfavourable prognosis in childhood medulloblastoma.
Gerber N, von Hoff K, von Bueren A, Treulieb W, Treulieb W, Deinlein F, Benesch M, Zwiener I, Soerensen N, Warmuth-Metz M, Pietsch T, Mittler U, Kuehl J, Kortmann R, Rutkowski S, Rutkowski S
EUR J CANCER. 2012;48(13):2028-2036.

p53 expression predicts dismal outcome for medulloblastoma patients with metastatic disease.
Gessi M, von Bueren A, Rutkowski S, Rutkowski S, Pietsch T
J NEURO-ONCOL. 2012;106(1):135-141.

Siglec-7 tetramers characterize B-cell subpopulations and leukemic blasts.
Gieseke F, Mang P, Viebahn S, Sonntag I, Kruchen A, Erbacher A, Pfeiffer M, Handgretinger R, Müller I
EUR J IMMUNOL. 2012;42(8):2176-2186.

Sonic hedgehog-associated medulloblastoma arising from the cochlear nuclei of the brainstem.
Grammel D, Warmuth-Metz M, von Bueren A, André O, Kool M, Pietsch T, Kretzschmar H, Rutkowski S, Rutkowski S, Pfister S, Schüller U
ACTA NEUROPATHOL. 2012;123(4):601-614.

Targeted therapeutics in treatment of children and young adults with solid tumors: an expert survey and review of the literature.
Grunewald T, Greulich N, Kontny U, Frühwald M, Rutkowski S, Kordes U, Scheurlen W, Schmidt W, Stachel D, Metzler M, Mittler U, Graf N, Benesch M, Burdach S
KLIN PADIATR. 2012;224(3):124-131.

Familial and acquired hemophagocytic lymphohistiocytosis.
Janka-Schaub G
ANNU REV MED. 2012;63:233-246.

Dissecting the genomic complexity underlying medulloblastoma.
Jones D, Jäger N, Kool M, Zichner T, Hutter B, Sultan M, Cho Y, Pugh T, Hovestadt V, Stütz A, Rausch T, Warnatz H, Ryzhova M, Bender S, Sturm D, Pleier S, Cin H, Pfaff E, Sieber L, Wittmann A, Remke M, Witt H, Hutter S, Tzaridis T, Weischenfeldt J, Raeder B, Avci M, Amstislavskiy V, Zapatka M, Weber U, Wang Q, Lasitschka B, Bartholomae C, Schmidt M, von Kalle C, Ast V, Lawerenz C, Eils J, Kabbe R, Benes V, van Sluis P, Koster J, Volckmann R, Shih D, Betts M, Russell R, Coco S, Tonini G, Schüller U, Hans V, Graf N, Kim Y, Monoranu C, Roggendorf W, Unterberg A, Herold-Mende C, Milde T, Kulozik A, von Deimling A, Witt O, Maass E, Rössler J, Ebinger M, Schuhmann M, Frühwald M, Hasselblatt M, Jabado N, Rutkowski S, von Bueren A, André O, Williamson D, Clifford S, McCabe M, Collins V, Wolf S, Wiemann S, Lehrach H, Brors B, Scheurlen W, Felsberg J, Reifenberger G, Northcott P, Taylor M, Meyerson M, Pomeroy S, Yaspo M, Korbel J, Korshunov A, Eils R, Pfister S, Lichter P
NATURE. 2012;488(7409):100-105.

Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas.
Kool M, Korshunov A, Remke M, Jones D, Schlanstein M, Northcott P, Cho Y, Koster J, Antoinette S, van Vuurden D, Clifford S, Pietsch T, von Bueren A, Rutkowski S, Rutkowski S, McCabe M, Collins V, Bäcklund M, Haberler C, Bourdeaut F, Delattre O, Doz F, Ellison D, Gilbertson R, Pomeroy S, Taylor M, Lichter P, Pfister S
ACTA NEUROPATHOL. 2012;123(4):473-484.

Loss of TP53 expression in immortalized choroid plexus epithelial cells results in increased resistance to anticancer agents
Krzyzankova M, Mertsch S, Koos B, Jeibmann A, Kruse A, Kordes U, Frühwald M, Wolff J, Paulus W, Hasselblatt M
J NEURO-ONCOL. 2012;109(3):449-55.

Basic biology and clinical application of multipotent mesenchymal stromal cells
Kuçi S, Henschler R, Müller I, Biagi E, Meisel R
Stem Cells Int. 2012;2012:185943.

Basic biology and clinical application of multipotent mesenchymal stromal cells: from bench to bedside.
Kuçi S, Henschler R, Müller I, Biagi E, Meisel R
Stem Cells Int. 2012;2012:185943.

Hyperfractionated versus conventional radiotherapy followed by chemotherapy in standard-risk medulloblastoma: results from the randomized multicenter HIT-SIOP PNET 4 trial.
Lannering B, Rutkowski S, Doz F, Pizer B, Gustafsson G, Navajas A, Massimino M, Reddingius R, Benesch M, Carrie C, Taylor R, Gandola L, Björk-Eriksson T, Giralt J, Oldenburger F, Pietsch T, Figarella-Branger D, Robson K, Forni M, Clifford S, Warmuth-Metz M, von Hoff K, Faldum A, Mosseri V, Kortmann R
J CLIN ONCOL. 2012;30(26):3187-3193.

Variant alleles of cytokine genes influence risk and clinical course of Langerhans cell histiocytosis.
Lehrnbecher T, Salzmann-Manrique E, Soerensen J, Beutel K, Janka-Schaub G, Gadner H, Minkov M
BRIT J HAEMATOL. 2012;156(1):138-141.

Distinct mutations in STXBP2 are associated with variable clinical presentations in patients with familial hemophagocytic lymphohistiocytosis type 5 (FHL5).
Pagel J, Beutel K, Lehmberg K, Koch F, Maul-Pavicic A, Rohlfs A, Al-Jefri A, Beier R, Lilian B, Ehlert K, Gross-Wieltsch U, Jorch N, Kremens B, Pekrun A, Sparber-Sauer M, Mejstrikova E, Wawer A, Ehl S, Zur Stadt U, Janka-Schaub G
BLOOD. 2012;119(25):6016-6024.

Occurrence of acute lymphoblastic leukemia and juvenile myelomonocytic leukemia in a patient with Noonan syndrome carrying the germline PTPN11 mutation p.E139D.
Pauli S, Steinemann D, Dittmann K, Wienands J, Shoukier M, Möschner M, Burfeind P, Manukjan G, Göhring G, Escherich G
AM J MED GENET A. 2012;158A(3):652-658.

IL-15-stimulated CD3/CD19-depleted stem-cell boosts in relapsed pediatric patients after haploidentical SCT.
Pfeiffer M, Schumm M, Müller I, Handgretinger R, Lang P
LEUKEMIA. 2012;26(11):2435-2439.

Pulmonary involvement in pediatric-onset multisystem Langerhans cell histiocytosis: effect on course and outcome.
Ronceray L, Pötschger U, Janka-Schaub G, Gadner H, Minkov M, Hematology G, Group O
J PEDIATR-US. 2012;161(1):123-129.

DWI of the brain: postmortal DWI of the brain in comparison with in vivo data.
Schmidt T, Fischer R, Acar S, Lorenzen M, Heinemann A, Wedegärtner U, Adam G, Yamamura J
FORENSIC SCI INT. 2012;220(1-3):180-183.

Letter to the editor
Schnell O, Pöschl J, Tonn J, Schüller U
BRAIN PATHOL. 2012;22(5):724.

Outcomes after induction failure in childhood acute lymphoblastic leukemia.
Schrappe M, Hunger S, Pui C, Saha V, Gaynon P, Baruchel A, Conter V, Otten J, Ohara A, Versluys A, Escherich G, Heyman M, Silverman L, Horibe K, Mann G, Camitta B, Harbott J, Riehm H, Richards S, Devidas M, Zimmermann M
NEW ENGL J MED. 2012;366(15):1371-1381.

Fatal EBV infection and variable clinical manifestations in an XLP-1 pedigree - rapid diagnosis of primary immunodeficiencies may save lives.
Sperl D, Benesch M, Urban C, Lackner H, Sovinz P, Speicher M, Uhrig S, Schwarzbraun T, Schwinger W, Zur Stadt U, Beutel K, Janka-Schaub G, Scarpatetti M, Seidel M
KLIN PADIATR. 2012;224(6):386-389.

Molecular subgroups of medulloblastoma: the current consensus.
Taylor M, Northcott P, Korshunov A, Remke M, Cho Y, Clifford S, Eberhart C, Parsons D, Rutkowski S, Gajjar A, Ellison D, Lichter P, Gilbertson R, Pomeroy S, Kool M, Pfister S
ACTA NEUROPATHOL. 2012;123(4):465-472.

In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice.
Terziyska N, Catarina C, Groiss V, Schneider K, Farkasova K, Ogris M, Wagner E, Ehrhardt H, Brentjens R, Zur Stadt U, Horstmann M, Quintanilla-Martinez L, Jeremias I
PLOS ONE. 2012;7(12):52798.

Risk factors for early death in children with haemophagocytic lymphohistiocytosis.
Trottestam H, Berglöf E, Horne A, Onelöv E, Beutel K, Lehmberg K, Sieni E, Silfverberg T, Aricò M, Janka-Schaub G, Henter J
ACTA PAEDIATR. 2012;101(3):313-318.

CNS PNET molecular subgroups with distinct clinical features.
von Bueren A, André O
LANCET ONCOL. 2012;13(8):753-754.

DNA copy number alterations in central primitive neuroectodermal tumors and tumors of the pineal region: an international individual patient data meta-analysis.
von Bueren A, André O, Hagel C, Hagel C, Cai H, Remke M, Hasselblatt M, Feuerstein B, Pernet S, Delattre O, Rutkowski S, Rutkowski S, Pfister S, Baudis M
J NEURO-ONCOL. 2012;109(2):415-423.

Mismatch repair deficiency
von Bueren A, Bacolod M, Hagel C, Heinimann K, Fedier A, Kordes U, Pietsch T, Koster J, Grotzer M, Friedman H, Marra G, Kool M, Rutkowski S
BRIT J CANCER. 2012;107(8):1399-408.

Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours.
von Bueren A, Bacolod M, Hagel C, Heinimann K, Fedier A, Kordes U, Pietsch T, Koster J, Grotzer M, Friedman H, Marra G, Kool M, Rutkowski S
BRIT J CANCER. 2012;107(8):1399-1408.

Medulloblastoma.
von Hoff K, Rutkowski S
Curr Treat Options Neurol. 2012;14(4):416-426.

Quantification of minimal residual disease (MRD) in acute lymphoblastic leukemia (ALL) using amplicon-fusion-site polymerase chain reaction (AFS-PCR).
Weber A, Taube S, Zur Stadt U, Horstmann M, Krohn K, Bradtke J, Teigler-Schlegel A, Leiblein S, Christiansen H
Exp Hematol Oncol. 2012;1(1):33.

Pediatric high grade glioma of the spinal cord: results of the HIT-GBM database.
Wolff B, Ng A, Roth D, Parthey K, Warmuth-Metz M, Eyrich M, Kordes U, Kortmann R, Pietsch T, Kramm C, Wolff J
J NEURO-ONCOL. 2012;107(1):139-146.

CPT SIOP
Wolff J, Hasselblatt M, Hartung S, Powell M, Garami M, Traunecker H, Thall P, Mahajan A, Kordes U, Sumerauer D
J NEURO-ONCOL. 2012;14:i153.

The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia.
Zuurbier L, Petricoin E, Vuerhard M, Calvert V, Kooi C, Buijs-Gladdines J, Smits W, Sonneveld E, Veerman A, Kamps W, Horstmann M, Pieters R, Meijerink J
HAEMATOLOGICA. 2012;97(9):1405-1413.

2011

Primary central nervous system primitive neuroectodermal tumors (CNS-PNETs) of the spinal cord in children: four cases from the German HIT database with a critical review of the literature.
Benesch M, Sperl D, von Bueren A, André O, von Hoff K, von Hoff K, Warmuth-Metz M, Ferrari R, Lassay L, Kortmann R, Rutkowski S, Rutkowski S
J NEURO-ONCOL. 2011;104(1):279-286.

Promising therapy results for lymphoid malignancies in children with chromosomal breakage syndromes (Ataxia teleangiectasia or Nijmegen-breakage syndrome): a retrospective survey.
Bienemann K, Burkhardt B, Modlich S, Meyer U, Möricke A, Bienemann K, Mauz-Körholz C, Escherich G, Zimmermann M, Körholz D, Janka-Schaub G, Schrappe M, Reiter A, Borkhardt A
BRIT J HAEMATOL. 2011;155(4):468-476.

Glioblastoma in childhood – Treatment and outcome of 7 patients
Burkhardt T, Emami P, Kordes U, Matschke J, Regelsberger J, Westphal M, Kammler G
2011.

A complex karyotype in an atypical teratoid/rhabdoid tumor: case report and review of the literature.
Coccé M, Lubieniecki F, Kordes U, Alderete D, Gallego M
J NEURO-ONCOL. 2011;104(1):375-380.

Meta-analysis of randomised trials comparing thiopurines in childhood acute lymphoblastic leukaemia.
Escherich G, Richards S, Stork L, Vora A
LEUKEMIA. 2011;25(6):953-959.

The long-term impact of in vitro drug sensitivity on risk stratification and treatment outcome in acute lymphoblastic leukemia of childhood (CoALL 06-97).
Escherich G, Troeger A, Gobel U, Graubner U, Pekrun A, Jorch N, Kaspers G, Zimmermann M, Zur Stadt U, Kazemir K, Pieters R, Horstmann M, Denboer M, Janka-Schaub G
HAEMATOLOGICA. 2011;96(6):854-862.

Outcome of 11 children with ependymoblastoma treated within the prospective HIT-trials between 1991 and 2006.
Gerber N, von Hoff K, von Bueren A, Treulieb W, Treulieb W, Warmuth-Metz M, Pietsch T, Soerensen N, Faldum A, Emser A, Schlegel P, Deinlein F, Rutkowski S, Rutkowski S
J NEURO-ONCOL. 2011;102(3):459-469.

Bone regeneration: stem cell therapies and clinical studies in orthopaedics and traumatology.
Gómez-Barrena E, Rosset P, Müller I, Giordano R, Bunu C, Layrolle P, Konttinen Y, Luyten F
J CELL MOL MED. 2011;15(6):1266-1286.

Nonsense mutation and inactivation of SMARCA4 (BRG1) in an atypical teratoid/rhabdoid tumor showing retained SMARCB1 (INI1) expression.
Hasselblatt M, Gesk S, Oyen F, Rossi S, Viscardi E, Giangaspero F, Giannini C, Judkins A, Frühwald M, Obser T, Schneppenheim R, Siebert R, Paulus W
AM J SURG PATHOL. 2011;35(6):933-935.

SV40 and p53 as team players in childhood lymphoproliferative disorders.
Heinsohn S, Scholz R, Kabisch H
INT J ONCOL. 2011;38(5):1307-1317.

Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia.
Homminga I, Pieters R, Langerak A, Rooi d, Johan J, Stubbs A, Verstegen M, Vuerhard M, Buijs-Gladdines J, Kooi C, Klous P, van Vlierberghe P, Ferrando A, Cayuela J, Verhaaf B, Horstmann M, Horstmann M, de Haas V, Wiekmeijer A, Pike-Overzet K, Staal F, de Laat W, Soulier J, Sigaux F, Meijerink J
CANCER CELL. 2011;19(4):484-497.

Subtle differences in CTL cytotoxicity determine susceptibility to hemophagocytic lymphohistiocytosis in mice and humans with Chediak-Higashi syndrome.
Jessen B, Maul-Pavicic A, Ufheil H, Vraetz T, Enders A, Lehmberg K, Längler A, Gross-Wieltsch U, Bay A, Kaya Z, Bryceson Y, Koscielniak E, Badawy S, Davies G, Hufnagel M, Schmitt-Graeff A, Aichele P, Zur Stadt U, Schwarz K, Ehl S
BLOOD. 2011;118(17):4620-4629.

Ectopic craniopharyngioma.
Kordes U, Flitsch J, Hagel C, Goebell E, Schwarz R, Herberhold T, von Bueren A, Rutkowski S, Müller H
KLIN PADIATR. 2011;223(3):176-177.

SIOP-CPT-2000 update
Kordes U, Kutluk T, Hasselblatt M, Pietsch A, Thall P, Wolff J
2011.

Parvovirus B19 infection and autoimmune hepatitis in a child with sickle cell anemia.
Kordes U, Schneppenheim R, Briem-Richter A, Scherpe S, Schäfer H
PEDIATR BLOOD CANCER. 2011;56(2):323-324.

Childhood medulloblastoma.
Massimino M, Giangaspero F, Garrè M, Gandola L, Poggi G, Biassoni V, Gatta G, Rutkowski S
CRIT REV ONCOL HEMAT. 2011;79(41):65-83.

Common large partial VWF gene deletion does not cause alloantibody formation in the Hungarian type 3 von Willebrand disease population.
Mohl A, Boda Z, Jager R, Losonczy H, Marosi A, Masszi T, Nagy E, Nemes L, Obser T, Oyen F, Radványi G, Schlammadinger [, Szélessy Z, Várkonyi A, Vezendy K, Vilimi B, Schneppenheim R, Bodó I
J THROMB HAEMOST. 2011;9(5):945-952.

Curative treatment for central nervous system medulloepithelioma despite residual disease after resection. Report of two cases treated according to the GPHO Protocol HIT 2000 and review of the literature.
Müller K, Zwiener I, Welker H, Maass E, Bongartz R, Berthold F, Pietsch T, Warmuth-Metz M, von Bueren A, Rutkowski S
STRAHLENTHER ONKOL. 2011;187(11):757-762.

The microtubule stabilizer patupilone (epothilone B) is a potent radiosensitizer in medulloblastoma cells.
Oehler C, von Bueren A, André O, Furmanova P, Broggini-Tenzer A, Rutkowski S, Rutkowski S, Frei K, Grotzer M, Pruschy M
NEURO-ONCOLOGY. 2011;13(9):1000-1010.

High-dose chemotherapy followed by autologous stem cell transplantation for metastatic rhabdomyosarcoma--a systematic review.
Peinemann F, Kröger N, Bartel C, Grouven U, Pittler M, Erttmann R, Kulig M
PLOS ONE. 2011;6(2):17127.

An aggressive systemic juvenile xanthogranuloma clonally related to a preceding T-cell acute lymphoblastic leukemia.
Perez-Becker R, Szczepanowski M, Leuschner I, Janka-Schaub G, Gokel M, Imschweiler T, Völpel S, Niehues T, Klapper W
PEDIATR BLOOD CANCER. 2011;56(5):859-862.

Increased cyclosporine concentrations in the absence of cyclosporine administration.
Peter A, Shipkova M, Wieland E, Schleicher E, Müller I
CLIN CHEM. 2011;57(5):670-673.

Expression of BARHL1 in medulloblastoma is associated with prolonged survival in mice and humans.
Pöschl J, Lorenz A, Hartmann W, von Bueren A, Kool M, Li S, Peraud A, Tonn J, Herms J, Xiang M, Rutkowski S, Kretzschmar H, Schüller U
ONCOGENE. 2011;30(47):4721-4730.

Expression of FoxM1 is required for the proliferation of medulloblastoma cells and indicates worse survival of patients.
Priller M, Pöschl J, Abrão L, von Bueren A, André O, Rutkowski S, Rutkowski S, Kretzschmar H, Schüller U
CLIN CANCER RES. 2011;17(21):6791-6801.

Expression of FoxM1 is required for the proliferation of medulloblastoma cells and indicates worse survival of patients
Priller M, Pöschl J, Abrão L, von Bueren A, Cho Y, Rutkowski S, Kretzschmar H, Schüller U
CLIN CANCER RES. 2011;17(21):6791-801.

FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma.
Remke M, Hielscher T, Korshunov A, Northcott P, Bender S, Kool M, Westermann F, Benner A, Cin H, Ryzhova M, Sturm D, Witt H, Haag D, Toedt G, Wittmann A, Schöttler A, von Bueren A, André O, Rutkowski S, Rutkowski S, Scheurlen W, Kulozik A, Taylor M, Lichter P, Pfister S
J CLIN ONCOL. 2011;29(29):3852-3861.

Characterisation of two novel large F8 deletions in patients with severe haemophilia A and factor VIII inhibitors.
Roth L, Marschalek R, Oldenburg J, Oyen F, Schneppenheim R
THROMB HAEMOSTASIS. 2011;105(2):279-284.

The pathophysiology of von Willebrand disease: therapeutic implications.
Schneppenheim R
THROMB RES. 2011;128 Suppl 1:3-7.

Regulation der primären Hämostase durch von-Willebrand-Faktor und ADAMTS13
Schneppenheim R, Budde U
HAMOSTASEOLOGIE. 2011;31(4):275-80.

[Von Willebrand factor and ADAMTS13 balancing primary haemostasis].
Schneppenheim R, Budde U
HAMOSTASEOLOGIE. 2011;31(4):275-280.

von Willebrand factor: the complex molecular genetics of a multidomain and multifunctional protein.
Schneppenheim R, Budde U
J THROMB HAEMOST. 2011;9 Suppl 1:209-215.

Genotype-phenotype study of familial haemophagocytic lymphohistiocytosis type 3.
Sieni E, Cetica V, Santoro A, Beutel K, Mastrodicasa E, Meeths M, Ciambotti B, Brugnolo F, Zur Stadt U, Pende D, Moretta L, Griffiths G, Henter J, Janka-Schaub G, Aricò M
J MED GENET. 2011;48(5):343-352.

A comparison between two semi-quantitative bleeding scales for the diagnosis and assessment of bleeding severity in type 1 von Willebrand disease.
Tosetto A, Rodeghiero F, Castaman G, Goodeve A, Federici A, Batlle J, Meyer D, Goudemand J, Eikenboom J, Schneppenheim R, Budde U, Ingerslev J, Lethagen S, Hill F, Peake I
HAEMOPHILIA. 2011;17(1):165-166.

Chemoimmunotherapy for hemophagocytic lymphohistiocytosis: long-term results of the HLH-94 treatment protocol.
Trottestam H, Horne A, Aricò M, Egeler R, Filipovich A, Gadner H, Imashuku S, Ladisch S, Webb D, Janka-Schaub G, Henter J, Society H
BLOOD. 2011;118(17):4577-4584.

Severe phototoxicity associated with long-term voriconazole treatment.
Vöhringer S, Schrum J, Ott H, Höger P
J DTSCH DERMATOL GES. 2011;9(4):274-276.

c-MYC expression sensitizes medulloblastoma cells to radio- and chemotherapy and has no impact on response in medulloblastoma patients.
von Bueren A, André O, Oehler C, von Hoff K, von Hoff K, Pruschy M, Seifert B, Gerber N, Warmuth-Metz M, Stearns D, Eberhart C, Rutkowski S, Rutkowski S, Grotzer M
BMC CANCER. 2011;11:74.

Late complete remission of supratentorial primitive neuroectodermal tumor (CNS-PNET) after multiple relapses.
von Bueren A, André O, Warmuth-Metz M, Schlegel P, Soerensen N, Krauss J, Roggendorf W, Pietsch T, Feiden W, Graf N, Pohl F, Flentje M, Rutkowski S, Rutkowski S
PEDIATR BLOOD CANCER. 2011;56(3):503-505.

Treatment of young children with localized medulloblastoma by chemotherapy alone: results of the prospective, multicenter trial HIT 2000 confirming the prognostic impact of histology.
von Bueren A, von Hoff K, von Hoff K, Pietsch T, Gerber N, Warmuth-Metz M, Deinlein F, Zwiener I, Faldum A, Fleischhack G, Benesch M, Krauss J, Kuehl J, Rutkowski S, Rutkowski S
NEURO-ONCOLOGY. 2011;13(6):669-679.

Frequency, risk-factors and survival of children with atypical teratoid rhabdoid tumors (AT/RT) of the CNS diagnosed between 1988 and 2004, and registered to the German HIT database.
von Hoff K, Hinkes B, Dannenmann-Stern E, von Bueren A, André O, Warmuth-Metz M, Soerensen N, Emser A, Zwiener I, Schlegel P, Kuehl J, Frühwald M, Kortmann R, Rutkowski S, Rutkowski S
PEDIATR BLOOD CANCER. 2011;57(6):978-985.

Outcome of children and adolescents with relapsed acute lymphoblastic leukaemia and non-response to salvage protocol therapy: a retrospective analysis of the ALL-REZ BFM Study Group.
von Stackelberg A, Völzke E, Kühl J, Seeger K, Schrauder A, Escherich G, Henze G, Tallen G, Group A
EUR J CANCER. 2011;47(1):90-97.

Recurrence in childhood medulloblastoma.
Warmuth-Metz M, Blashofer S, von Bueren A, von Hoff K, von Hoff K, Bison B, Pohl F, Kortmann R, Rutkowski S, Rutkowski S
J NEURO-ONCOL. 2011;103(3):705-711.

Mesenchymal stromal cells for treatment of steroid-refractory GvHD: a review of the literature and two pediatric cases.
Wernicke C, Grunewald T, Juenger H, Kuci S, Kuci Z, Koehl U, Müller I, Doering M, Peters C, Lawitschka A, Kolb H, Bader P, Burdach S, von Luettichau I
Int Arch Med. 2011;4(1):27.

High dose methotrexate for pediatric high grade glioma: results of the HIT-GBM-D Pilot study.
Wolff J, Kortmann R, Wolff B, Pietsch T, Peters O, Schmid H, Rutkowski S, Warmuth-Metz M, Kramm C
J NEURO-ONCOL. 2011;102(3):433-442.

Pancreatic exocrine function and cardiac iron in patients with iron overload and with thalassemia.
Yamamura J, Grosse R, Jarisch A, Janka-Schaub G, Nielsen P, Adam G, Fischer R
PEDIATR BLOOD CANCER. 2011;57(4):674-676.

Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia.
Zenatti P, Ribeiro D, Li W, Zuurbier L, Silva M, Paganin M, Tritapoe J, Hixon J, Silveira A, Cardoso B, Sarmento L, Correia N, Toribio M, Kobarg J, Horstmann M, Pieters R, Brandalise S, Ferrando A, Meijerink J, Durum S, Yunes J, Barata J
NAT GENET. 2011;43(10):932-939.

2010

Adjuvant dendritic cell-based tumour vaccination for children with malignant brain tumours.
Ardon H, Steven D, Frank V, Claes L, Kramm C, Rutkowski S, Wolff J, Gool V, Stefaan W
PEDIATR BLOOD CANCER. 2010;54(4):519-525.

Clinical outcome of children with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia treated between 1995 and 2005.
Aricò M, Schrappe M, Hunger S, Carroll W, Conter V, Galimberti S, Manabe A, Saha V, Baruchel A, Vettenranta K, Horibe K, Benoit Y, Pieters R, Escherich G, Silverman L, Pui C, Valsecchi M
J CLIN ONCOL. 2010;28(31):4755-4761.

Ependymoma of the spinal cord in children and adolescents: a retrospective series from the HIT database.
Benesch M, Weber-Mzell D, Gerber N, von Hoff K, Deinlein F, Krauss J, Warmuth-Metz M, Kortmann R, Pietsch T, Driever P, Quehenberger F, Urban C, Rutkowski S
J NEUROSURG-PEDIATR. 2010;6(2):137-144.

Proton beam therapy for loco-regional control of a recurrent mixed malignant germ cell tumor of the skull in a 22-month-old girl.
Calaminus G, Göbel U, Schrum J, Wittkugel O, Westphal M, Timmermann B
KLIN PADIATR. 2010;222(3):175-179.

[Guidelines for diagnosis and treatment of secondary iron overload in patients with congenital anemia].
Cario H, Grosse R, Janssen G, Jarisch A, Meerpohl J, Strauss G
KLIN PADIATR. 2010;222(6):399-406.

Homozygous type 2N R854W von Willebrand factor is poorly secreted and causes a severe von Willebrand disease phenotype.
Castaman G, Giacomelli S, Jacobi P, Obser T, Budde U, Rodeghiero F, Haberichter S, Schneppenheim R
J THROMB HAEMOST. 2010;8(9):2011-2016.

Validation of a rapid test (VWF-LIA) for the quantitative determination of von Willebrand factor antigen in type 1 von Willebrand disease diagnosis within the European multicenter study MCMDM-1VWD.
Castaman G, Tosetto A, Cappelletti A, Goodeve A, Federici A, Batlle J, Meyer D, Goudemand J, Eikenboom J, Schneppenheim R, Budde U, Ingerslev J, Lethagen S, Hill F, Peake I, Rodeghiero F
THROMB RES. 2010;126(3):227-231.

The impact of bleeding history, von Willebrand factor and PFA-100(®) on the diagnosis of type 1 von Willebrand disease: results from the European study MCMDM-1VWD.
Castaman G, Tosetto A, Goodeve A, Federici A, Lethagen S, Ulrich B, Batlle J, Meyer D, Mazurier C, Goudemand J, Eikenboom J, Schneppenheim R, Ingerslev J, Habart D, Hill F, Peake I, Rodeghiero F
BRIT J HAEMATOL. 2010;151(3):245-251.

STXBP2 mutations in children with familial haemophagocytic lymphohistiocytosis type 5.
Cetica V, Santoro A, Gilmour K, Sieni E, Beutel K, Pende D, Marcenaro S, Koch F, Grieve S, Wheeler R, Zhao F, Zur Stadt U, Griffiths G, Aricò M
J MED GENET. 2010;47(9):595-600.

Systematic review of the addition of vincristine plus steroid pulses in maintenance treatment for childhood acute lymphoblastic leukaemia - an individual patient data meta-analysis involving 5,659 children
Eden T, Pieters R, Yetgin S, Olcay L, Dibar E, Conter V, Masera G, Valsecchi M, Dacou-Voutetakis C, Henze G, Loening L, Schrappe M, von Stackelberg A, Zimmermann M, Attarbaschi A, Gadner H, Mann G, Brandalise S, Carroll W, Devidas M, Gaynon P, Hunger S, Nachman J, Janka-Schaub G, Stary J, Gelber R, Bierings M, Kamps W, Otten J, Suciu S, Viana M, Baruchel A, Ortega J, Magyarosy E, Perez C, Steinberg D, Tsurusawa M, Zintl F, Matsuzaki A, Lilleyman J, Richards S, Steinherz P, Kochupillai V, de Toledo J, Appelbaum F, Campbel M, Cheng C, Pei D, Pui C, Kukure P, Nakazawa S, Elphinstone T, Evans V, Gettins L, Hicks C, MacKinnon L, Morris P, Wade R, Wise C
BRIT J HAEMATOL. 2010;149(5):722-733.

Cooperative study group for childhood acute lymphoblastic leukaemia (COALL)
Escherich G, Horstmann M, Zimmermann M, Janka-Schaub G
LEUKEMIA. 2010;24(2):298-308.

Non-cerebellar primitive neuroectodermal tumors (PNET): summary of the Milan consensus and state of the art workshop on marrow ablative chemotherapy with hematopoietic cell rescue for malignant brain tumors of childhood and adolescents.
Fangusaro J, Massimino M, Rutkowski S, Gururangan S
PEDIATR BLOOD CANCER. 2010;54(4):638-640.

Ongoing remission after intensive ALL-type chemotherapy in pediatric intestinal T-cell lymphoma.
Friedrich C, Schrum J, Chott A, Janka-Schaub G, Kabisch H
PEDIATR BLOOD CANCER. 2010;54(4):610-612.

The mutation N528S in the von Willebrand factor (VWF) propeptide causes defective multimerization and storage of VWF.
Haberichter S, Ulrich B, Obser T, Schneppenheim S, Wermes C, Schneppenheim R
BLOOD. 2010;115(22):4580-4587.

Polymorphic variation within the VWF gene contributes to the failure to detect mutations in patients historically diagnosed with type 1 von Willebrand disease from the MCMDM-1VWD cohort.
Hampshire D, Burghel G, Goudemand J, Bouvet L, Eikenboom J, Schneppenheim R, Ulrich B, Peake I, Goodeve A
HAEMATOLOGICA. 2010;95(12):2163-2165.

von Willebrand factor variant p.Arg924Gln marks an allele associated with reduced von Willebrand factor and factor VIII levels.
Hickson N, Hampshire D, Winship P, Goudemand J, Schneppenheim R, Budde U, Castaman G, Rodeghiero F, Federici A, James P, Peake I, Eikenboom J, Goodeve A
J THROMB HAEMOST. 2010;8(9):1986-1993.

Low physiologic oxygen tensions reduce proliferation and differentiation of human multipotent mesenchymal stromal cells
Holzwarth C, Vaegler M, Gieseke F, Pfister S, Handgretinger R, Kerst G, Müller I
BMC CELL BIOL. 2010;11:11.

Difficulties in diagnosing congenital thrombotic thrombocytopenic purpura.
Klukowska A, Niewiadomska E, Ulrich B, Oyen F, Schneppenheim R
J PEDIAT HEMATOL ONC. 2010;32(2):103-107.

Neonatal cholestasis and glucose-6-P-dehydrogenase deficiency.
Kordes U, Briem-Richter A, Santer R, Schäfer H, Singer D, Sonntag J, Steuerwald U, Schneppenheim R, Janka-Schaub G
PEDIATR BLOOD CANCER. 2010;54(5):758-760.

Neonatal cholestasis in glucose-6-phosphate dehydrogenase deficiency.
Kordes U, Briem-Richter A, Santer R, Schäfer H, Singer D, Sonntag J, Steuerwald U, Schneppenheim R, Janka-Schaub G
PEDIATR BLOOD CANCER. 2010;54(5):758-766.

Clinical and molecular features in patients with atypical teratoid rhabdoid tumor or malignant rhabdoid tumor.
Kordes U, Gesk S, Frühwald M, Graf N, Leuschner I, Hasselblatt M, Jeibmann A, Oyen F, Peters O, Pietsch T, Siebert R, Schneppenheim R
GENE CHROMOSOME CANC. 2010;49(2):176-181.

Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification.
Korshunov A, Remke M, Werft W, Benner A, Ryzhova M, Witt H, Sturm D, Wittmann A, Schöttler A, Felsberg J, Reifenberger G, Rutkowski S, Scheurlen W, Kulozik A, von Deimling A, Lichter P, Pfister S
J CLIN ONCOL. 2010;28(18):3054-3060.

Improved outcome with hematopoietic stem cell transplantation in a poor prognostic subgroup of infants with mixed-lineage-leukemia (MLL)-rearranged acute lymphoblastic leukemia: results from the Interfant-99 Study.
Mann G, Attarbaschi A, Schrappe M, Paola D, Peters C, Hann I, Giulio D, Felice M, Lausen B, Leblanc T, Szczepanski T, Ferster A, Janka-Schaub G, Rubnitz J, Silverman Lewis B, Stary J, Campbell M, Li C, Suppiah R, Biondi A, Vora A, Valsecchi M, Pieters R, Group I
BLOOD. 2010;116(15):2644-2650.

Phase II window study on rituximab in newly diagnosed pediatric mature B-cell non-Hodgkin's lymphoma and Burkitt leukemia.
Meinhardt A, Burkhardt B, Zimmermann M, Borkhardt A, Kontny U, Klingebiel T, Berthold F, Janka-Schaub G, Klein C, Kabickova E, Klapper W, Attarbaschi A, Schrappe M, Reiter A, Group B
J CLIN ONCOL. 2010;28(19):3115-3121.

Loss of SMARCB1/INI1 expression in poorly differentiated chordomas.
Mobley B, McKenney J, Bangs C, Callahan K, Yeom K, Schneppenheim R, Hayden M, Cherry A, Gokden M, Edwards M, Fisher P, Vogel H
ACTA NEUROPATHOL. 2010;120(6):745-753.

Profiling of histone H3 lysine 9 trimethylation levels predicts transcription factor activity and survival in acute myeloid leukemia.
Müller-Tidow C, Klein H, Hascher A, Isken F, Tickenbrock L, Thoennissen N, Agrawal-Singh S, Tschanter P, Disselhoff C, Wang Y, Becker A, Thiede C, Ehninger G, Zur Stadt U, Koschmieder S, Seidl M, Müller F, Schmitz W, Schlenke P, McClelland M, Berdel W, Dugas M, Serve H, Leukemia S
BLOOD. 2010;116(18):3564-3571.

Laboratory diagnosis of von Willebrand disease.
Patzke J, Schneppenheim R
HAMOSTASEOLOGIE. 2010;30(4):203-206.

TP53 mutation is frequently associated with CTNNB1 mutation or MYCN amplification and is compatible with long-term survival in medulloblastoma.
Pfaff E, Remke M, Sturm D, Benner A, Witt H, Till M, von Bueren A, André O, Wittmann A, Schöttler A, Jorch N, Graf N, Kulozik A, Witt O, Scheurlen W, Rutkowski S, Rutkowski S, Taylor M, Tabori U, Lichter P, Korshunov A, Pfister S
J CLIN ONCOL. 2010;28(35):5188-5196.

Atypical familial hemophagocytic lymphohistiocytosis due to mutations in UNC13D and STXBP2 overlaps with primary immunodeficiency diseases.
Rohr J, Beutel K, Maul-Pavicic A, Vraetz T, Thiel J, Warnatz K, Bondzio I, Gross-Wieltsch U, Schündeln M, Schütz B, Woessmann W, Groll A, Strahm B, Pagel J, Speckmann C, Janka-Schaub G, Griffiths G, Schwarz K, Zur Stadt U, Ehl S
HAEMATOLOGICA. 2010;95(12):2080-2087.

Chronic inflammatory bowel disease as key manifestation of atypical ARTEMIS deficiency
Rohr J, Pannicke U, Döring M, Schmitt-Graeff A, Wiech E, Busch A, Speckmann C, Müller I, Lang P, Handgretinger R, Fisch P, Schwarz K, Ehl S
J CLIN IMMUNOL. 2010;30(2):314-20.

Medulloblastoma in young children.
Rutkowski S, Cohen B, Finlay J, Luksch R, Ridola V, Valteau-Couanet D, Hara J, Garre M, Grill J
PEDIATR BLOOD CANCER. 2010;54(4):635-637.

Survival and prognostic factors of early childhood medulloblastoma: an international meta-analysis.
Rutkowski S, von Hoff K, Emser A, Zwiener I, Pietsch T, Figarella-Branger D, Giangaspero F, Ellison D, Garre M, Biassoni V, Grundy R, Finlay J, Dhall G, Raquin M, Grill J
J CLIN ONCOL. 2010;28(33):4961-4968.

Using ImageJ for the quantitative analysis of flow-based adhesion assays in real-time under physiologic flow conditions.
Sascha M, Klinkhardt U, Schneppenheim R, Harder S
PLATELETS. 2010;21(1):60-66.

Germline nonsense mutation and somatic inactivation of SMARCA4/BRG1 in a family with rhabdoid tumor predisposition syndrome.
Schneppenheim R, Frühwald M, Gesk S, Hasselblatt M, Jeibmann A, Kordes U, Kreuz M, Leuschner I, Subero M, Obser T, Oyen F, Oyen F, Vater I, Siebert R
AM J HUM GENET. 2010;86(2):279-284.

A cluster of mutations in the D3 domain of von Willebrand factor correlates with a distinct subgroup of von Willebrand disease: type 2A/IIE.
Schneppenheim R, Michiels J, Obser T, Oyen F, Pieconka A, Schneppenheim S, Will K, Zieger B, Ulrich B
BLOOD. 2010;115(23):4894-4901.

Disabling c-Myc in childhood medulloblastoma and atypical teratoid/rhabdoid tumor cells by the potent G-quadruplex interactive agent S2T1-6OTD.
Shalaby T, von Bueren A, André O, Hürlimann M, Fiaschetti G, Castelletti D, Masayuki T, Nagasawa K, Arcaro A, Jelesarov I, Shin-ya K, Grotzer M
MOL CANCER THER. 2010;9(1):167-179.

Long-term outcome in children with relapsed acute lymphoblastic leukemia after time-point and site-of-relapse stratification and intensified short-course multidrug chemotherapy: results of trial ALL-REZ BFM 90.
Tallen G, Ratei R, Mann G, Kaspers G, Niggli F, Karachunsky A, Ebell W, Escherich G, Schrappe M, Klingebiel T, Fengler R, Henze G, von Stackelberg A
J CLIN ONCOL. 2010;28(14):2339-2347.

Large cell/anaplastic medulloblastoma: outcome according to myc status, histopathological, and clinical risk factors.
von Hoff K, Hartmann W, von Bueren A, Oscar A, Gerber N, Grotzer M, Rutkowski S, Rutkowski S
PEDIATR BLOOD CANCER. 2010;54(3):369-376.

Intensive chemotherapy improves survival in pediatric high-grade glioma after gross total resection: results of the HIT-GBM-C protocol.
Wolff J, Driever P, Erdlenbruch B, Kortmann R, Rutkowski S, Pietsch T, Parker C, Metz M, Gnekow A, Kramm C
CANCER-AM CANCER SOC. 2010;116(3):705-712.

[28-year old female patient with respiratory insufficiency, elevated liver enzymes, pancytopenia and fever].
Wolschke C, Fiedler W, Habermann C, Janka-Schaub G, Kluge S
INTERNIST. 2010;51(11):1434-1438.

Distribution of cardiac iron measured by magnetic resonance imaging (MRI)-R*2.
Yamamura J, Grosse R, Graessner J, Janka-Schaub G, Adam G, Fischer R
J MAGN RESON IMAGING. 2010;32(5):1104-1109.

Severe bleeding diathesis associated with moderate thrombocytopenia - diagnostic workup of seven family members with type 2B von Willebrand's disease.
Zdziarska J, Iwaniec T, Skotnicki A, Musia J, Schneppenheim R, Budde U, Kentouche K
HAEMOPHILIA. 2010;16(6):958-962.

NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols.
Zuurbier L, Homminga I, Calvert V, Te Winkel M, Buijs-Gladdines J, Kooi C, Smits W, Sonneveld E, Veerman A, Kamps W, Horstmann M, Petricoin E, Pieters R, Meijerink J
LEUKEMIA. 2010;24(12):2014-2022.

2009

Fatal Epstein-Barr virus infection in a case of familial hemophagocytic lymphohistiocytosis with syntaxin-11 mutation.
Albayrak M, Kaya Z, Yilmaz-Keskin E, Zur Stadt U, Koçak U, Gürsel T
TURKISH J PEDIATR. 2009;51(4):371-374.

Prognostic value of minimal residual disease quantification before allogeneic stem-cell transplantation in relapsed childhood acute lymphoblastic leukemia: the ALL-REZ BFM Study Group.
Bader P, Kreyenberg H, Henze G, Eckert C, Reising M, Willasch A, Barth A, Borkhardt A, Peters C, Handgretinger R, Sykora K, Holter W, Kabisch H, Klingebiel T, von Stackelberg A
J CLIN ONCOL. 2009;27(3):377-384.

Infection of T lymphocytes in Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in children of non-Asian origin.
Beutel K, Gross-Wieltsch U, Wiesel T, Zur Stadt U, Janka-Schaub G, Wagner H
PEDIATR BLOOD CANCER. 2009;53(2):184-190.

ITI with high-dose FIX and combined immunosuppressive therapy in a patient with severe haemophilia B and inhibitor.
Beutel K, Hauch H, Rischewski J, Kordes U, Schneppenheim J, Schneppenheim R
HAMOSTASEOLOGIE. 2009;29(2):155-157.

Infection of T lymphocytes in non-Asian patients with epstein-barr virus-associated hemophagocytic-response.
Beutel K, Janka-Schaub G
PEDIATR BLOOD CANCER. 2009.

Standardized MRD quantification in European ALL trials: Proceedings of the Second International Symposium on MRD assessment in Kiel, Germany, 18-20 September 2008.
Brüggemann M, Schrauder A, Raff T, Pfeifer H, Dworzak M, Ottmann O, Asnafi V, Baruchel A, Bassan R, Benoit Y, Biondi A, Cavé H, Dombret H, Fielding A, Foà R, Gökbuget N, Goldstone A, Goulden N, Henze G, Hoelzer D, Janka-Schaub G, Macintyre E, Pieters R, Rambaldi A, Ribera J, Schmiegelow K, Spinelli O, Stary J, von Stackelberg A, Kneba M, Schrappe M, van Dongen J
LEUKEMIA. 2009.

Recurrent loss, but lack of mutations, of the SMARCB1 tumor suppressor gene in T-cell prolymphocytic leukemia with TCL1A-TCRAD juxtaposition.
Bug S, Dürig J, Oyen F, Klein-Hitpass L, Martin-Subero J, Harder L, Baudis M, Arnold N, Kordes U, Dührsen U, Schneppenheim R, Siebert R
CANCER GENET CYTOGEN. 2009;192(1):44-47.

Variations in the ratio between von Willebrand factor and its cleaving protease during systemic inflammation and association with severity and prognosis of organ failure.
Claus R, Bockmeyer C, Ulrich B, Kentouche K, Sossdorf M, Hilberg T, Schneppenheim R, Reinhart K, Bauer M, Brunkhorst F, Lösche W
THROMB HAEMOSTASIS. 2009;101(2):239-247.

Acquired vorinostat resistance shows partial cross-resistance to 'second-generation' HDAC inhibitors and correlates with loss of histone acetylation and apoptosis but not with altered HDAC and HAT activities.
Dedes K, Dedes I, Imesch P, von Bueren A, André O, Fink D, Fedier A
ANTI-CANCER DRUG. 2009;20(5):321-333.

A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study.
Den B, Monique L, Slegtenhorst v, Marjon [, Menezes D, Renée X, Cheok [, Meyling H, Buijs-Gladdines [, Jessica G, Peters [, Susan T, Zutven V, Laura J, Beverloo [, Berna H, Spek V, Peter J, Escherich G, Gaby [, Horstmann M, Martin A, Janka-Schaub G, Gritta E, Kamps [, Willem A, Evans [, William E, Pieters [, Rob [
LANCET ONCOL. 2009;10(2):125-134.

A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome
Den Boer M, van Slegtenhorst M, De Menezes R, Cheok M, Buijs-Gladdines J, Peters S, Van Zutven L, Beverloo H, Van der Spek P, Escherich G, Horstmann M, Janka-Schaub G, Kamps W, Evans W, Pieters R
LANCET ONCOL. 2009;10(2):125-34.

Acquired von Willebrand syndrome as side effect of valproic acid therapy in children is rare.
Eberl W, Budde U, Bentele K, Christen H, Knapp R, Mey A, Schneppenheim R
HAMOSTASEOLOGIE. 2009;29(2):137-142.

Expression of fourteen von Willebrand factor mutations identified in patients with type 1 von Willebrand disease from the MCMDM-1VWD study.
Eikenboom J, Hilbert L, Ribba A, Hommais A, Habart D, Messenger S, Al-Buhairan A, Guilliatt A, Lester W, Mazurier C, Meyer D, Fressinaud E, Budde U, Will K, Schneppenheim R, Obser T, Marggraf O, Eckert E, Castaman G, Rodeghiero F, Federici A, Batlle J, Goudemand J, Ingerslev J, Lethagen S, Oyen F, Peake I, Goodeve A
J THROMB HAEMOST. 2009.

Cooperative study group for childhood acute lymphoblastic leukaemia (COALL): long-term results of trials 82,85,89,92 and 97.
Escherich G, Horstmann M, Zimmermann M, Janka-Schaub G
LEUKEMIA. 2009.

The CD70/CD27 pathway is critical for stimulation of an effective cytotoxic T cell response against B cell precursor acute lymphoblastic leukemia.
Glouchkova L, Ackermann B, Zibert A, Meisel R, Siepermann M, Janka-Schaub G, Goebel U, Troeger A, Dilloo D
J IMMUNOL. 2009;182(1):718-725.

Second allogeneic stem cell transplantation in myeloid malignancies.
Hartwig M, Ocheni S, Asenova S, Wiedemann B, Zabelina T, Ayuketang Ayuk F, Kabisch H, Erttmann R, Kröger N, Zander A, Bacher U
ACTA HAEMATOL-BASEL. 2009;122(4):185-192.

Cribriform neuroepithelial tumor (CRINET): a nonrhabdoid ventricular tumor with INI1 loss and relatively favorable prognosis.
Hasselblatt M, Oyen F, Gesk S, Kordes U, Brigitte W, Bergmann M, Schmid H, Frühwald M, Schneppenheim R, Siebert R, Paulus W
J NEUROPATH EXP NEUR. 2009;68(12):1249-1255.

Evaluation of SV40 in osteosarcoma and healthy population: a Hungarian-German study.
Heinsohn S, Szendroi M, Bielack S, Zur Stadt U, Kabisch H
ONCOL REP. 2009;21(2):289-297.

Hemophagocytic lymphohistiocytosis: when the immune system runs amok.
Janka-Schaub G
KLIN PADIATR. 2009;221(5):278-285.

Case-control study on the therapy of childhood cancer and the occurrence of second malignant neoplasms in Germany.
Kaatsch P, Reinisch I, Spix C, Berthold F, Janka-Schaub G, Mergenthaler A, Michaelis J, Blettner M
CANCER CAUSE CONTROL. 2009;20(6):965-980.

Neuroonkologie
Kammler G, Kordes U, Hornung D, LINHART D, Hagel C
2009. Neuropädiatrie - Evidenzbasierte Therapie. Elsevier: 215-239.

HLA-mismatched unrelated donors as an alternative graft source for allogeneic stem cell transplantation after antithymocyte globulin-containing conditioning regimen.
Kröger N, Zabelina T, Binder T, Ayuketang Ayuk F, Bacher U, Amtsfeld G, Lellek H, Schrum J, Erttmann R, Eiermann T, Zander A
BIOL BLOOD MARROW TR. 2009;15(4):454-462.

Pancytopenia in a 4-year-old boy. 22q11.2 microdeletion syndrome.
Lehmberg K, Rohr J, Schneppenheim R, Sommerfeld K, Janka-Schaub G
ACTA PAEDIATR. 2009;98(5):769-770, 912-914.

Outcome of congenital acute lymphoblastic leukemia treated on the Interfant-99 protocol.
Linden v, Marieke H, Valsecchi M, Paola D, Janka-Schaub G, Janka G, Leblanc T, Felice M, Andrea B, Campbell M, Hann I, Rubnitz J, Stary J, Szczepanski T, Vora A, Ferster A, Hovi L, Silverman L, Pieters R
BLOOD. 2009;114(18):3764-3768.

Pharmacokinetics of high-dose methotrexate in infants treated for acute lymphoblastic leukemia.
Lönnerholm G, Valsecchi M, Paola D, Schrappe M, Hovi L, Campbell M, Mann G, Janka-Schaub G, Li C, Stary J, Hann I, Pieters R
PEDIATR BLOOD CANCER. 2009;52(5):596-601.

Heterozygous missense protein S mutation in a young boy with incomplete tetraplegia.
Mauz-Koerholz C, Müller T, Kunze C, Schneppenheim R, Bernstaedt M, Koerholz D
KLIN PADIATR. 2009;221(3):180.

Clinical presentation of Griscelli syndrome type 2 and spectrum of RAB27A mutations.
Meeths M, Bryceson Y, Rudd E, Zheng C, Wood S, Ramme K, Beutel K, Hasle H, Heilmann C, Hultenby K, Ljunggren H, Fadeel B, Nordenskjöld M, Henter J
PEDIATR BLOOD CANCER. 2009.

New insights to the MLL recombinome of acute leukemias.
Meyer C, Kowarz E, Hofmann J, Renneville A, Zuna J, Trka J, Ben Abdelali R, Macintyre E, De Braekeleer E, De Braekeleer M, Delabesse E, de Oliveira M, Cavé H, Clappier E, van Dongen J, Balgobind B, van den Heuvel-Eibrink M, Beverloo H, Panzer-Grümayer R, Teigler-Schlegel A, Harbott J, Kjeldsen E, Schnittger S, Koehl U, Gruhn B, Heidenreich O, Chan L, Yip S, Krzywinski M, Eckert C, Möricke A, Schrappe M, Alonso C, Schäfer B, Krauter J, Lee D, Zur Stadt U, Te Kronnie G, Sutton R, Izraeli S, Trakhtenbrot L, Lo Nigro L, Tsaur G, Fechina L, Szczepanski T, Strehl S, Ilencikova D, Molkentin M, Burmeister T, Dingermann T, Klingebiel T, Marschalek R
LEUKEMIA. 2009;23(8):1490-1499.

Italian Society of Hematology guidelines for thalassemia and non-invasive iron measurements.
Nielsen P, Engelhardt R, Grosse R, Janka-Schaub G, Harmatz P, Fischer R
HAEMATOLOGICA. 2009;94(2):294-296.

Allogeneic blood SCT for children with Hurler's syndrome: results from the German multicenter approach MPS-HCT 2005.
Sauer M, Meissner B, Fuchs D, Gruhn B, Kabisch H, Erttmann R, Suttorp M, Beilken A, Luecke T, Welte K, Grigull L, Sykora K
BONE MARROW TRANSPL. 2009;43(5):375-381.

Basic research and clinical applications of non-hematopoietic stem cells, 4-5 April 2008, Tubingen, Germany
Schäfer R, Dominici M, Müller I, Horwitz E, Asahara T, Bulte J, Bieback K, Le Blanc K, Bühring H, Capogrossi M, Dazzi F, Gorodetsky R, Henschler R, Handgretinger R, Kajstura J, Kluger P, Lange C, Luettichau I, Mertsching H, Schrezenmeier H, Sievert K, Strunk D, Verfaillie C, Northoff H
CYTOTHERAPY. 2009;11(2):245-55.

Molecular analysis and clinical aspects of four patients with Chédiak-Higashi syndrome (CHS).
Scherber E, Beutel K, Ganschow R, Schulz A, Janka-Schaub G, Zur Stadt U
CLIN GENET. 2009.

Paediatric haemostaseology.
Schneppenheim R
HAMOSTASEOLOGIE. 2009;29(2):133.

Shear-induced unfolding activates von Willebrand factor A2 domain for proteolysis.
Schneppenheim R, Baldauf C, Stacklies W, Obser T, Pieconka A, Schneppenheim S, Budde U, Zhou J, Gräter F
J THROMB HAEMOST. 2009;7(12):2096-2105.

Response to DDAVP in children with von Willebrand disease type 2.
Schneppenheim R, Budde U, Beutel K, Hassenpflug W, Hauch H, Obser T, Oyen F, Schneppenheim S, Schrum J
HAMOSTASEOLOGIE. 2009;29(2):143-148.

The problem of novel FVIII missense mutations for haemophilia A genetic counseling.
Schneppenheim R, Schröder J, Obser T, Oyen F, Schneppenheim S, Oldenburg J
HAMOSTASEOLOGIE. 2009;29(2):158-160.

Patients with early relapse of primary hemophagocytic syndromes or with persistent CNS involvement may benefit from immediate hematopoietic stem cell transplantation.
Sparber-Sauer M, Hönig M, Schulz A, Zur Stadt U, Schütz C, Debatin K, Friedrich W
BONE MARROW TRANSPL. 2009;44(6):333-338.

Hemophagocytic lymphohistiocytosis and Kawasaki disease: Combined manifestation and differential diagnosis.
Titze U, Janka-Schaub G, Schneider E, Prall F, Haffner D, Classen C
PEDIATR BLOOD CANCER. 2009;53(3):493-495.

WT1 mutations in T-ALL.
Tosello V, Mansour M, Barnes K, Paganin M, Sulis M, Jenkinson S, Allen C, Gale R, Linch D, Palomero T, Real P, Murty V, Yao X, Richards S, Goldstone A, Rowe J, Basso G, Wiernik P, Paietta E, Pieters R, Horstmann M, Meijerink J, Ferrando A
BLOOD. 2009;114(5):1038-1045.

Treatment of the X-linked lymphoproliferative, Griscelli and Chédiak-Higashi syndromes by HLH directed therapy.
Trottestam H, Beutel K, Meeths M, Carlsen N, Heilmann C, Pasi S, Webb D, Hasle H, Henter J
PEDIATR BLOOD CANCER. 2009;52(2):268-272.

A novel type 2A von Willebrand factor mutation (V1499E) associated with variable clinical expression.
van Den H, Esther [, Laat d, Bas [, Eckmann [, Carel M, Michiels [, Jan J, Schneppenheim R, Reinhard [, Ulrich B, Mourik v, Jan A, Versteegh [, Florens G
J PEDIAT HEMATOL ONC. 2009;31(4):277-280.

RNA interference-mediated c-MYC inhibition prevents cell growth and decreases sensitivity to radio- and chemotherapy in childhood medulloblastoma cells.
von Bueren A, André O, Shalaby T, Oehler-Jänne C, Arnold L, Stearns D, Eberhart C, Arcaro A, Pruschy M, Grotzer M
BMC CANCER. 2009;9:10.

Dose reductions of vincristine in children with medulloblastoma treated in the maintenance arm of the prospective multicenter trial HIT'91.
von Bueren A, von Hoff K, Benesch M, Rutkowski S
KLIN PADIATR. 2009;221(6):396-397.

Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11.
Zur Stadt U, Rohr J, Seifert W, Koch F, Grieve S, Pagel J, Strauss J, Kasper B, Nürnberg G, Becker C, Maul-Pavicic A, Beutel K, Janka-Schaub G, Griffiths G, Ehl S, Hennies H
AM J HUM GENET. 2009;85(4):482-492.

2008

Anti-thymocyte globulin overcomes the negative impact of HLA mismatching in transplantation from unrelated donors.
Ayuketang Ayuk F, Diyachenko G, Zabelina T, Panse J, Wolschke C, Eiermann T, Binder T, Fehse B, Erttmann R, Kabisch H, Bacher U, Kröger N, Zander A
EXP HEMATOL. 2008;36(8):1047-1054.

Leukemia-associated NF1 inactivation in patients with pediatric T-ALL and AML lacking evidence for neurofibromatosis.
Balgobind [, Brian V, Vlierberghe V, Pieter [, van Den O, Ans M, Beverloo [, Berna H, Terlouw-Kromosoeto [, Joan N, Wering v, Elisabeth R, Reinhardt [, Dirk [, Horstmann M, Martin [, Kaspers [, Gertjan J, Pieters [, Rob [, Zwaan [, Michel C, Heuvel-Eibrink V, Marry M, Meijerink [, Jules P
BLOOD. 2008;111(8):4322-4328.

Gene expression signatures predictive of early response and outcome in high-risk childhood acute lymphoblastic leukemia: A Children's Oncology Group Study [corrected].
Bhojwani D, Kang H, Menezes R, Yang W, Sather H, Moskowitz N, Min D, Potter J, Harvey R, Hunger S, Seibel N, Raetz E, Pieters R, Horstmann M, Relling M, Boer d, Monique L, Willman C, Carroll W
J CLIN ONCOL. 2008;26(27):4376-4384.

Gene expression signatures predictive of early response and outcome in high-risk childhood acute lymphoblastic leukemia
Bhojwani D, Kang H, Menezes R, Yang W, Sather H, Moskowitz N, Min D, Potter J, Harvey R, Hunger S, Seibel N, Raetz E, Pieters R, Horstmann M, Relling M, den Boer M, Willman C, Carroll W
J CLIN ONCOL. 2008;26(27):4376-84.

Inflammation-associated ADAMTS13 deficiency promotes formation of ultra-large von Willebrand factor.
Bockmeyer C, Claus R, Budde U, Kentouche K, Schneppenheim R, Lösche W, Reinhart K, Brunkhorst F
HAEMATOLOGICA. 2008;93(1):137-140.

Targeting the phosphoinositide 3-kinase isoform p110delta impairs growth and survival in neuroblastoma cells.
Boller D, Schramm A, Doepfner K, Shalaby T, von Bueren A, André O, Eggert A, Grotzer M, Arcaro A
CLIN CANCER RES. 2008;14(4):1172-1181.

Secondary malignant neoplasms after intensive treatment of relapsed acute lymphoblastic leukaemia in childhood.
Borgmann A, Zinn C, Hartmann R, Herold R, Kaatsch P, Escherich G, Möricke A, Henze G, von Stackelberg A
EUR J CANCER. 2008;44(2):257-268.

Detailed von Willebrand factor multimer analysis in patients with von Willebrand disease in the European study, molecular and clinical markers for the diagnosis and management of type 1 von Willebrand disease (MCMDM-1VWD).
Budde U, Schneppenheim R, Eikenboom J, Goodeve A, Will K, Drewke E, Castaman G, Rodeghiero F, Federici A, Batlle J, Pérez A, Meyer D, Mazurier C, Goudemand J, Ingerslev J, Habart D, Vorlova Z, Holmberg L, Lethagen S, Pasi J, Hill F, Peake I
J THROMB HAEMOST. 2008;6(5):762-771.

Response to desmopressin is influenced by the genotype and phenotype in type 1 von Willebrand disease (VWD): results from the European Study MCMDM-1VWD.
Castaman G, Lethagen S, Federici A, Tosetto A, Goodeve A, Budde U, Batlle J, Meyer D, Mazurier C, Fressinaud E, Goudemand J, Eikenboom J, Schneppenheim R, Ingerslev J, Vorlova Z, Habart D, Holmberg L, Pasi J, Hill F, Peake I, Rodeghiero F
BLOOD. 2008;111(7):3531-3539.

Treatment of neuroblastoma with human natural antibodies.
Erttmann R
AUTOIMMUN REV. 2008;7(6):496-500.

Lack of Thy1 (CD90) expression in neuroblastomas is correlated with impaired survival.
Fiegel H, Kaifi J, Quaas A, Varol E, Krickhahn A, Metzger R, Sauter G, Till H, Izbicki J, Erttmann R, Kluth D
PEDIATR SURG INT. 2008;24(1):101-105.

Midkine is highly expressed in neuroblastoma tissues.
Fiegel H, Kaifi J, Wachowiak R, Quaas A, Aridome K, Ichihara-Tanaka K, Muramatsu T, Metzger R, Izbicki J, Erttmann R, Kluth D, Till H
PEDIATR SURG INT. 2008;24(12):1355-1359.

Analysis of the CC chemokine receptor 5Delta32 polymorphism in pediatric liver transplant recipients.
Fischer-Maas L, Schneppenheim R, Oyen F, Grabhorn E, Briem-Richter A, Fischer L, Ganschow R
PEDIATR TRANSPLANT. 2008;12(7):769-772.

Impact of reduction of therapy on infectious complications in childhood acute lymphoblastic leukemia.
Graubner U, Porzig S, Jorch N, Kolb R, Wessalowski R, Escherich G, Janka-Schaub G
PEDIATR BLOOD CANCER. 2008;50(2):259-263.

Genetic defects in von Willebrand disease type 3 in Indian and Greek patients.
Gupta P, Saxena R, Adamtziki E, Budde U, Oyen F, Obser T, Schneppenheim R
BLOOD CELL MOL DIS. 2008;41(2):219-222.

Identification of type 1 von Willebrand disease patients with reduced von Willebrand factor survival by assay of the VWF propeptide in the European study: molecular and clinical markers for the diagnosis and management of type 1 VWD (MCMDM-1VWD).
Haberichter S, Castaman G, Budde U, Peake I, Goodeve A, Rodeghiero F, Federici A, Batlle J, Meyer D, Mazurier C, Goudemand J, Eikenboom J, Schneppenheim R, Ingerslev J, Vorlova Z, Habart D, Holmberg L, Lethagen S, Pasi J, Hill F, Montgomery R
BLOOD. 2008;111(10):4979-4985.

Emergence of linezolid resistance in a methicillin resistant Staphylococcus aureus strain.
Hentschke M, Saager B, Horstkotte M, Scherpe S, Wolters M, Kabisch H, Grosse R, Heisig P, Aepfelbacher M, Rohde H
INFECTION. 2008;36(1):85-87.

Frequency and spectrum of central nervous system involvement in 193 children with haemophagocytic lymphohistiocytosis.
Horne A, Trottestam H, Aricò M, Egeler R, Filipovich A, Gadner H, Imashuku S, Ladisch S, Webb D, Janka-Schaub G, Henter J
BRIT J HAEMATOL. 2008;140(3):327-335.

Impaired capacity for acute endogenous fibrinolysis in smokers is restored by ascorbic acid.
Kähler J, Koeke K, Karstens M, Schneppenheim R, Meinertz T, Heitzer T
FREE RADICAL BIO MED. 2008;44(3):315-321.

Successful donor-lymphocyte infusion for extreme immune-hemolysis following unrelated BMT in a patient with X-linked chronic granulomatous disease and McLeod phenotype.
Kordes U, Binder T, Eiermann T, Hassenpflug-Diedrich B, Hassan M, Beutel K, Nagy M, Kabisch H, Schneppenheim R
BONE MARROW TRANSPL. 2008;42(3):219-220.

Non-surgical management of advanced cardiac lymphoma.
Lilje C, Thiel C, Weil J, Schrum J, Stork A
J PEDIATR-US. 2008;152(3):440.

Reactivations in multisystem Langerhans cell histiocytosis: data of the international LCH registry.
Minkov M, Steiner M, Pötschger U, Aricò M, Braier J, Donadieu J, Grois N, Henter J, Janka-Schaub G, McClain K, Weitzman S, Windebank K, Ladisch S, Gadner H
J PEDIATR-US. 2008;153(5):1-2, 700-705.

An Alu-mediated novel large deletion is the most frequent cause of type 3 von Willebrand disease in Hungary.
Mohl A, Marschalek R, Masszi T, Nagy E, Obser T, Oyen F, Sallai K, Bodó I, Schneppenheim R
J THROMB HAEMOST. 2008;6(10):1729-1735.

EBV reactivation and post transplant lymphoproliferative disorders following allogeneic SCT.
Ocheni S, Kröger N, Zabelina T, Sobottka I, Ayuketang Ayuk F, Wolschke C, Muth A, Lellek H, Petersen L, Erttmann R, Kabisch H, Zander A, Bacher U
BONE MARROW TRANSPL. 2008;42(3):181-186.

Temperature sensitivity of phospho-Ser(473)-PKB/AKT.
Oehler-Jänne C, von Bueren A, André O, Vuong V, Hollenstein A, Grotzer M, Pruschy M
BIOCHEM BIOPH RES CO. 2008;375(3):399-404.

The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia.
Pieter V, van Grotel M, Tchinda J, Lee C, Beverloo H, Spek v, Peter J, Stubbs A, Cools J, Nagata K, Fornerod M, Horstmann M, Horstmann M, Wering v, Elisabeth R, Soulier J, Pieters R, Meijerink J
BLOOD. 2008;111(9):4668-4680.

[Inborn and acquired von Willebrand disease]
Schneppenheim R, Budde U
HAMOSTASEOLOGIE. 2008;28(5):312-319.

Review and update of the use of urokinase in the prevention and management of CVAD-related complications in pediatric oncology patients.
Simon A, Udo B, Lieber K, Beutel K, Fleischhack G
AM J INFECT CONTROL. 2008;36(1):54-58.

Genotype-phenotype study of familial haemophagocytic lymphohistiocytosis due to perforin mutations.
Trizzino A, Zur Stadt U, Ueda I, Risma K, Janka G, Ishii E, Beutel K, Sumegi J, Cannella S, Pende D, Mian A, Henter J, Janka-Schaub G, Santoro A, Filipovich A, Aricò M
J MED GENET. 2008;45(1):15-21.

High expression of CD40 on B-cell precursor acute lymphoblastic leukemia blasts is an independent risk factor associated with improved survival and enhanced capacity to up-regulate the death receptor CD95.
Troeger A, Glouchkova L, Ackermann B, Escherich G, Meisel R, Hanenberg H, Boer d, Monique L, Janka-Schaub G, Janka-Schaub G, Goebel U, Laws H, Dilloo D
BLOOD. 2008;112(4):1028-1034.

Reduced expression and defective modulation of TNF receptor/ligand family molecules on proB-ALL blasts.
Troeger A, Glouchkova L, Escherich G, Siepermann M, Hanenberg H, Janka-Schaub G, Göbel U, Ackermann B, Dilloo D
KLIN PADIATR. 2008;220(6):353-357.

Erythrocytapheresis: Erythrocytapheresis:
Ullrich H, Fischer R, Grosse R, Kordes U, Schubert C, Altstadt B, Andreu G
TRANSFUS MED HEMOTH. 2008;35(1):24-30.

Monoallelic or biallelic LMO2 expression in relation to the LMO2 rearrangement status in pediatric T-cell acute lymphoblastic leukemia.
Van Vlierberghe P, Beverloo H, Buijs-Gladdines J, van Wering E, Horstmann M, Pieters R, Meijerink J
LEUKEMIA. 2008;22(7):1434-1437.

Cooperative genetic defects in TLX3 rearranged pediatric T-ALL.
Van Vlierberghe P, Homminga I, Zuurbier L, Gladdines-Buijs J, van Wering E, Horstmann M, Beverloo H, Pieters R, Meijerink J
LEUKEMIA. 2008;22(4):762-770.

Impairment of intellectual functions after surgery and posterior fossa irradiation in children with ependymoma is related to age and neurologic complications
von Hoff K, Kieffer V, Habrand J, Kalifa C, Dellatolas G, Grill J
BMC CANCER. 2008;8:15.

High-dose compared with intermediate-dose methotrexate in children with a first relapse of acute lymphoblastic leukemia.
von Stackelberg A, Hartmann R, Bührer C, Fengler R, Janka-Schaub G, Reiter A, Mann G, Schmiegelow K, Ratei R, Klingebiel T, Ritter J, Henze G
BLOOD. 2008;111(5):2573-2580.

2007

DNA methylation of tumor suppressor genes in clinical remission predicts the relapse risk in acute myeloid leukemia.
Agrawal S, Unterberg M, Koschmieder S, Zur Stadt U, Brunnberg U, Verbeek W, Büchner T, Berdel W, Serve H, Müller-Tidow C
CANCER RES. 2007;67(3):1370-1377.

Insulin-like factor 3 levels in cord blood and serum from children
Bay K, Virtanen H, Hartung S, Ivell R, Main K, Skakkebaek N, Andersson A, Toppari J
J CLIN ENDOCR METAB. 2007;92(10):4020-7.

Recent developments in iron chelation therapy.
Cario H, Janka-Schaub G, Janssen G, Jarisch A, Strauss G, Kohne E
KLIN PADIATR. 2007;219(3):158-165.

Antisense treatment of IGF-IR induces apoptosis and enhances chemosensitivity in central nervous system atypical teratoid/rhabdoid tumours cells.
D'cunja J, Shalaby T, Rivera P, von Bueren A, Patti R, Heppner F, Arcaro A, Rorke-Adams L, Phillips P, Grotzer M
EUR J CANCER. 2007;43(10):1581-1589.

Daunorubicin-induced cell kill with 1-hour versus 24-hour infusions: a randomized comparison in children with newly diagnosed acute lymphoblastic leukemia.
Escherich G, Göbel U, Jorch N, Spaar H, Janka-Schaub G
KLIN PADIATR. 2007;219(3):134-138.

The histone deacetylase inhibitors suberoylanilide hydroxamic (Vorinostat) and valproic acid induce irreversible and MDR1-independent resistance in human colon cancer cells.
Fedier A, Dedes K, Imesch P, von Bueren A, Andre O, Fink D
INT J ONCOL. 2007;31(3):633-641.

Thrombotic microangiopathy in a 17-year-old patient: TTP, HUS or a bit of both?
Gerth J, Busch M, Oyen F, Schneppenheim R, Keller T, Budde U, Groene H, Wolf G
CLIN NEPHROL. 2007;68(6):405-411.

Which clinical and biological tumor markers proved predictive in the prospective multicenter trial HIT'91--implications for investigating childhood medulloblastoma.
Grotzer M, von Hoff K, von Bueren A, Shalaby T, Hartmann W, Warmuth-Metz M, Emser A, Kortmann R, Kuehl J, Pietsch T, Rutkowski S
KLIN PADIATR. 2007;219(6):312-317.

Submicroscopic bone marrow involvement in isolated extramedullary relapses in childhood acute lymphoblastic leukemia: a more precise definition of "isolated" and its possible clinical implications, a collaborative study of the Resistant Disease Committee of the International BFM study group.
Hagedorn N, Acquaviva C, Fronkova E, von Stackelberg A, Barth A, Zur Stadt U, Schrauder A, Trka J, Gaspar N, Seeger K, Henze G, Cavé H, Eckert C
BLOOD. 2007;110(12):4022-4029.

Feasibility and outcome of reduced-intensity conditioning in haploidentical transplantation
Handgretinger R, Chen X, Pfeiffer M, Müller I, Feuchtinger T, Hale G, Lang P
ANN NY ACAD SCI. 2007;1106:279-89.

Determination of the prognostic value of loss of heterozygosity at the retinoblastoma gene in osteosarcoma.
Heinsohn S, Evermann U, Zur Stadt U, Bielack S, Kabisch H
INT J ONCOL. 2007;30(5):1205-1214.

HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis.
Henter J, Horne A, Aricó M, Egeler R, Filipovich A, Imashuku S, Ladisch S, McClain K, Webb D, Winiarski J, Janka-Schaub G
PEDIATR BLOOD CANCER. 2007;48(2):124-131.

Familial and acquired hemophagocytic lymphohistiocytosis.
Janka-Schaub G
EUR J PEDIATR. 2007;166(2):95-109.

Hemophagocytic syndromes.
Janka-Schaub G
BLOOD REV. 2007;21(5):245-253.

Almost normal cognitive function in patients during therapy for childhood acute lymphoblastic leukemia without cranial irradiation according to ALL-BFM 95 and COALL 06-97 protocols: results of an Austrian-German multicenter longitudinal study and implications for follow-up.
Krappmann P, Paulides M, Stöhr W, Ittner E, Plattig B, Nickel P, Lackner H, Schrappe M, Janka-Schaub G, Beck J, Langer T
PEDIATR HEMAT ONCOL. 2007;24(2):101-109.

Retransplantation with stem cells from mismatched related donors after graft rejection in pediatric patients
Lang P, Müller I, Greil J, Bader P, Schumm M, Pfeiffer M, Hoelle W, Klingebiel T, Heinzelmann F, Belka C, Schlegel P, Kremens B, Woessmann W, Handgretinger R
BLOOD CELL MOL DIS. 2007;40(1):33-9.

From neonates to adolescents--the diagnostic significance of pitted erythrocytes in hyposplenic and asplenic children.
Lehmberg K, Steinhausen B, Janka-Schaub G
KLIN PADIATR. 2007;219(6):339-342.

Interferon-gamma mediated up-regulation of caspase-8 sensitizes medulloblastoma cells to radio- and chemotherapy.
Meister N, Shalaby T, von Bueren A, Rivera P, Patti R, Oehler C, Pruschy M, Grotzer M
EUR J CANCER. 2007;43(12):1833-1841.

Gene transfer of SHIP-1 inhibits proliferation of juvenile myelomonocytic leukemia cells carrying KRAS2 or PTPN11 mutations.
Metzner A, Horstmann M, Fehse B, Ortmeyer G, Niemeyer C, Stocking C, Mayr G, Jücker M
GENE THER. 2007;14(8):699-703.

Outcome of treatment in children with hypodiploid acute lymphoblastic leukemia.
Nachman J, Heerema N, Sather H, Camitta B, Forestier E, Harrison C, Dastugue N, Schrappe M, Pui C, Basso G, Silverman L, Janka-Schaub G
BLOOD. 2007;110(4):1112-1115.

A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial.
Pieters R, Schrappe M, Paola D, Hann I, Giulio D, Felice M, Hovi L, LeBlanc T, Szczepanski T, Ferster A, Janka-Schaub G, Rubnitz J, Silverman L, Stary J, Campbell M, Li C, Mann G, Suppiah R, Biondi A, Vora A, Valsecchi M
LANCET. 2007;370(9583):240-250.

Cloning and characterization of dihydrofolate reductase from a facultative alkaliphilic and halotolerant bacillus strain
Redecke L, Brehm M, Bredehorst R
Extremophiles : life under extreme conditions. 2007;11(1):75-83.

Prognostic relevance of clinical and biological risk factors in childhood medulloblastoma: results of patients treated in the prospective multicenter trial HIT'91.
Rutkowski S, von Bueren A, von Hoff K, Hartmann W, Shalaby T, Deinlein F, Warmuth-Metz M, Soerensen N, Emser A, Udo B, Mittler U, Urban C, Benesch M, Kortmann R, Schlegel P, Kuehl J, Pietsch T, Grotzer M
CLIN CANCER RES. 2007;13(9):2651-2657.

Accessibility and quality of secondary care rheumatology services for people with inflammatory arthritis: a regional survey.
Sandhu R, Treharne G, Justice E, Jordan A, Saravana S, Obrenovic K, Erb N, Kitas G, Rowe I
CLIN MED. 2007;7(6):579-584.

A common 253-kb deletion involving VWF and TMEM16B in German and Italian patients with severe von Willebrand disease type 3.
Schneppenheim R, Castaman G, Federici A, Kreuz W, Marschalek R, Oldenburg J, Oyen F, Budde U
J THROMB HAEMOST. 2007;5(4):722-728.

Polypharmacy among people with rheumatoid arthritis: the role of age, disease duration and comorbidity.
Treharne G, Douglas K, Iwaszko J, Panoulas V, Hale E, Mitton D, Piper H, Erb N, Kitas G
Musculoskeletal Care. 2007;5(4):175-190.

High nerve growth factor receptor (p75NTR) expression is a favourable prognostic factor in paediatric B cell precursor-acute lymphoblastic leukaemia.
Troeger A, Gudowius S, Escherich G, Boer d, Monique L, Glouchkova L, Ackermann B, Meisel R, Laws H, Groeger M, Wessalowski R, Willers R, Harbott J, Pieters R, Janka-Schaub G, Janka-Schaub G, Hanenberg H, Dilloo D
BRIT J HAEMATOL. 2007;139(3):450-457.

Up-regulation of c-FLIPS+R upon CD40 stimulation is associated with inhibition of CD95-induced apoptosis in primary precursor B-ALL.
Troeger A, Schmitz I, Siepermann M, Glouchkova L, Gerdemann U, Janka-Schaub G, Schulze-Osthoff K, Dilloo D
BLOOD. 2007;110(1):384-387.

Survivin and its prognostic significance in pediatric acute B-cell precursor lymphoblastic leukemia.
Troeger A, Siepermann M, Escherich G, Meisel R, Willers R, Gudowius S, Moritz T, Laws H, Hanenberg H, Goebel U, Janka-Schaub G, Mahotka C, Dilloo D
HAEMATOLOGICA. 2007;92(8):1043-1050.

Role of survivin splice variants in pediatric acute precursor B lymphoblastic leukemia.
Tröger A, Siepermann M, Mahotka C, Wethkamp N, Bülle H, Laws H, Escherich G, Janka-Schaub G, Göbel U, Dilloo D
KLIN PADIATR. 2007;219(3):127-133.

Analysis of minimal residual disease by Ig/TCR gene rearrangements: guidelines for interpretation of real-time quantitative PCR data.
van der Velden V, Cazzaniga G, Schrauder A, Hancock J, Bader P, Panzer-Grumayer E, Flohr T, Sutton R, Cave H, Madsen H, Cayuela J, Trka J, Eckert C, Foroni L, Zur Stadt U, Beldjord K, Raff T, van der Schoot C, van Dongen J
LEUKEMIA. 2007;21(4):604-611.

Salbutamol exhibits androgenic activity in vitro.
von Bueren A, André O, Ma R, Schlumpf M, Lichtensteiger W
BRIT J SPORT MED. 2007;41(12):874-878.

Anti-proliferative activity of the quassinoid NBT-272 in childhood medulloblastoma cells.
von Bueren A, André O, Shalaby T, Rajtarova J, Stearns D, Eberhart C, Helson L, Arcaro A, Grotzer M
BMC CANCER. 2007;7:19.

2006

A phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with beta-thalassemia.
Cappellini M, Cohen A, Piga A, Bejaoui M, Perrotta S, Agaoglu L, Aydinok Y, Kattamis A, Kilinc Y, Porter J, Capra M, Galanello R, Fattoum S, Drelichman G, Magnano C, Verissimo M, Athanassiou-Metaxa M, Giardina P, Kourakli-Symeonidis A, Janka-Schaub G, Coates T, Vermylen C, Olivieri N, Thuret I, Opitz H, Ressayre-Djaffer C, Marks P, Alberti D
BLOOD. 2006;107(9):3455-3462.

Comparable results in patients with acute lymphoblastic leukemia after related and unrelated stem cell transplantation.
Dahlke J, Kröger N, Zabelina T, Ayuketang Ayuk F, Wolschke C, Renges H, Krüger W, Kruell A, Hinke A, Erttmann R, Kabisch H, Zander A
BONE MARROW TRANSPL. 2006;37(2):155-163.

Quantitative multiplexed profiling of cellular signaling networks using phosphotyrosine-specific DNA-tagged SH2 domains.
Dierck K, Machida K, Voigt A, Thimm J, Horstmann M, Fiedler W, Mayer B, Nollau P
NAT METHODS. 2006;3(9):737-744.

Ovarian small cell carcinoma of the hypercalcemic type in children and adolescents: a prognostically unfavorable but curable disease.
Distelmaier F, Calaminus G, Harms D, Sträter R, Kordes U, Fleischhack G, Göbel U, Schneider D
CANCER-AM CANCER SOC. 2006;107(9):2298-2306.

Linkage analysis in families diagnosed with type 1 von Willebrand disease in the European study, molecular and clinical markers for the diagnosis and management of type 1 VWD
Eikenboom J, Van Marion V, Putter H, Goodeve A, Rodeghiero F, Castaman G, Federici A, Batlle J, Meyer D, Mazurier C, Goudemand J, Schneppenheim R, Budde U, Ingerslev J, Vorlova Z, Habart D, Holmberg L, Lethagen S, Pasi J, Hill F, Peake I
J THROMB HAEMOST. 2006;4(4):774-82.

Non-linkage of familial rhabdoid tumors to SMARCB1 implies a second locus for the rhabdoid tumor predisposition syndrome.
Frühwald M, Hasselblatt M, Wirth S, Köhler G, Schneppenheim R, Subero J, Siebert R, Kordes U, Jürgens H, Vormoor J
PEDIATR BLOOD CANCER. 2006;47(3):273-278.

Risk factors for diabetes insipidus in langerhans cell histiocytosis.
Grois N, Pötschger U, Prosch H, Minkov M, Arico M, Braier J, Henter J, Janka-Schaub G, Ladisch S, Ritter J, Steiner M, Unger E, Gadner H
PEDIATR BLOOD CANCER. 2006;46(2):228-233.

Treatment with caspofungin in immunocompromised paediatric patients: a multicentre survey.
Groll A, Attarbaschi A, Schuster F, Herzog N, Grigull L, Dworzak M, Beutel K, Laws H, Lehrnbecher T
J ANTIMICROB CHEMOTH. 2006;57(3):527-535.

The outcome of molecular-cytogenetic subgroups in pediatric T-cell acute lymphoblastic leukemia: a retrospective study of patients treated according to DCOG or COALL protocols.
Grotel v, Martine [, Meijerink [, Jules P, Beverloo [, Berna H, Langerak [, Anton W, Buys-Gladdines [, Jessica G, Schneider [, Pauline [, Poulsen [, Tim S, Den B, Monique L, Horstmann M, Martin [, Kamps [, Willem A, Veerman [, Anjo J, Wering v, Elisabeth R, Noesel v, Max M, Pieters [, Rob [
HAEMATOLOGICA. 2006;91(9):1212-1221.

Impact of mutations in the von Willebrand factor A2 domain on ADAMTS13-dependent proteolysis.
Hassenpflug W, Ulrich B, Obser T, Angerhaus D, Drewke E, Schneppenheim S, Schneppenheim R
BLOOD. 2006;107(6):2339-2345.

Expression of the outcome predictor in acute leukemia 1 (OPAL1) gene is not an independent prognostic factor in patients treated according to COALL or St Jude protocols.
Holleman A, Boer d, Monique L, Cheok M, Kazemier K, Pei D, Janka-Schaub G, Janka-Schaub G, Göbel U, Graubner U, Pui C, Evans W, Pieters R
BLOOD. 2006;108(6):1984-1990.

The expression of 70 apoptosis genes in relation to lineage, genetic subtype, cellular drug resistance, and outcome in childhood acute lymphoblastic leukemia.
Holleman A, Boer d, Monique L, Menezes d, Renée X, Cheok M, Janka-Schaub G, Kazemier K, Janka-Schaub G, Göbel U, Graubner U, Evans W, Pieters R
BLOOD. 2006;107(2):769-776.

In vitro sensitivity and cross-resistance to deoxynucleoside analogs in childhood acute leukemia.
Hubeek I, Peters G, Broekhuizen R, Zwaan C, Kaaijk P, Wering v, Elisabeth S, Gibson B, Janka-Schaub G, Janka-Schaub G, Boer d, Monique L, Pieters R, Kaspers G
HAEMATOLOGICA. 2006;91(1):17-23.

von Willebrand factor-cleaving protease (ADAMTS13) in the course of stem cell transplantation
Kentouche K, Zintl F, Angerhaus D, Fuchs D, Hermann J, Schneppenheim R, Budde U
SEMIN THROMB HEMOST. 2006;32(2):98-104.

RETRACTED: Modified high-performance liquid chromatographic conditions for determination of inosine 5'-monophosphate dehydrogenase activity inerythrocytes.
Khalil P, Erb N, Khalil M, Escherich G, Janka-Schaub G
J Pharmacol Toxicol Methods. 2006.

Validation and application of a high-performance liquid chromatographic-based assay for determination of the inosine 5'-monophosphate dehydrogenase activity in erythrocytes.
Khalil P, Erb N, Khalil M, Escherich G, Janka-Schaub G
J CHROMATOGR B ANALYT TECHNOL BIOMED LIFE SCI. 2006;842(1):1-7.

Expression of SOX9 and SOX10 in central neuroepithelial tumor.
Kordes U, Hagel C
J NEURO-ONCOL. 2006;80(2):151-155.

Quantitative mRNA expression analysis of neurotrophin-receptor TrkC and oncogene c-MYC from formalin-fixed, paraffin-embedded primitive neuroectodermal tumor samples.
Kunz F, Shalaby T, Lang D, von Bueren A, Hainfellner J, Slavc I, Tabatabai G, Grotzer M
NEUROPATHOLOGY. 2006;26(5):393-399.

Cellular origins of testicular dysgenesis in rats exposed in utero to di(n-butyl) phthalate
Mahood I, McKinnell C, Walker M, Hallmark N, Scott H, Fisher J, Rivas A, Hartung S, Ivell R, Mason J, Sharpe R
INT J ANDROL. 2006;29(1):148-54; discussion 181-5.

Differential expression of p73 isoforms in relation to drug resistance in childhood T-lineage acute lymphoblastic leukaemia.
Meier M, Den B, Meijerink [, Broekhuis [, Passier [, Wering v, Janka-Schaub G, Pieters R
LEUKEMIA. 2006;20(8):1377-1384.

A common origin of the 4143insA ADAMTS13 mutation.
Schneppenheim R, Hovinga K, Johanna A, Becker T, Ulrich B, Karpman D, Brockhaus W, Hrachovinová I, Oyen F, Oyen F, Rittich S, von Rosen J, Tjønnfjord G, Pimanda J, Wienker T, Lämmle B
THROMB HAEMOSTASIS. 2006;96(1):3-6.

Diagnosis and treatment of catheter-related infections in paediatric oncology: an update.
Simon A, Bode U, Beutel K
CLIN MICROBIOL INFEC. 2006;12(7):606-620.

Silencing of the tumor suppressor gene FHIT is highly characteristic for MLL gene rearranged infant acute lymphoblastic leukemia.
Stam [, Den B, Passier [, Janka-Schaub G, Sallan [, Armstrong [, Pieters R
LEUKEMIA. 2006;20(2):264-271.

Incidence of additional genetic changes in the TEL and AML1 genes in DCOG and COALL-treated t(12;21)-positive pediatric ALL, and their relation with drug sensitivity and clinical outcome.
Stams [, Beverloo [, Den B, Menezes d, Stigter [, Drunen v, Ramakers-van-Woerden [, Loonen [, Wering v, Janka-Schaub G, Pieters R
LEUKEMIA. 2006;20(3):410-416.

Molecular and clinical spectrum of type I plasminogen deficiency
Tefs K, Gueorguieva M, Klammt J, Allen C, Aktas D, Anlar F, Aydogdu S, Brown D, Ciftci E, Contarini P, Dempfle C, Dostalek M, Eisert S, Gökbuget A, Günhan O, Hidayat A, Hügle B, Isikoglu M, Irkec M, Joss S, Klebe S, Kneppo C, Kurtulus I, Mehta R, Ornek K, Schneppenheim R, Seregard S, Sweeney E, Turtschi S, Veres G, Zeitler P, Ziegler M, Schuster V
BLOOD. 2006;108(9):3021-6.

Mutation spectrum in children with primary hemophagocytic lymphohistiocytosis: molecular and functional analyses of PRF1, UNC13D, STX11, and RAB27A.
Udo Z, Beutel K, Kolberg S, Schneppenheim R, Kabisch H, Janka-Schaub G, Hennies H
HUM MUTAT. 2006;27(1):62-68.

The outcome of molecular-cytogenetic subgroups in pediatric T-cell acute lymphoblastic leukemia
van Grotel M, Meijerink J, Beverloo H, Langerak A, Buys-Gladdines J, Schneider P, Poulsen T, den Boer M, Horstmann M, Kamps W, Veerman A, van Wering E, van Noesel M, Pieters R
HAEMATOLOGICA. 2006;91(9):1212-21.

Intracranial hemorrhage in a term newborn with severe von Willebrand disease type 3 associated with sinus venous thrombosis.
Wetzstein V, Ulrich B, Oyen F, Ding X, Herrmann J, Liebig B, Schneppenheim R
HAEMATOLOGICA. 2006;91(12):60.

2005

The seventh international childhood acute lymphoblastic leukemia workshop report: Palermo, Italy, January 29--30, 2005.
Aricó M, Baruchel A, Bertrand Y, Biondi A, Conter V, Eden T, Gadner H, Gaynon P, Horibe K, Hunger S, Janka-Schaub G, Masera G, Nachman J, Pieters R, Schrappe M, Schmiegelow K, Valsecchi M, Pui C
LEUKEMIA. 2005;19(7):1145-1152.

Resistance to cytarabine and gemcitabine and in vitro selection of transduced cells after retroviral expression of cytidine deaminase in human hematopoietic progenitor cells.
Bardenheuer W, Lehmberg K, Rattmann I, Brueckner A, Schneider A, Sorg U, Seeber S, Moritz T, Flasshove M
LEUKEMIA. 2005;19(12):2281-2288.

Insulin-like factor 3 serum levels in 135 normal men and 85 men with testicular disorders
Bay K, Hartung S, Ivell R, Schumacher M, Jürgensen D, Jorgensen N, Holm M, Skakkebaek N, Andersson A
J CLIN ENDOCR METAB. 2005;90(6):3410-8.

Myeloablative megatherapy with autologous stem-cell rescue versus oral maintenance chemotherapy as consolidation treatment in patients with high-risk neuroblastoma: a randomised controlled trial.
Berthold F, Boos J, Burdach S, Erttmann R, Henze G, Hermann J, Klingebiel T, Kremens B, Schilling F, Schrappe M, Simon T, Hero B
LANCET ONCOL. 2005;6(9):649-658.

[Diagnostics and management of central venous line infections in pediatric cancer patients]
Beutel K, Simon A
KLIN PADIATR. 2005;217(1):91-100.

Development and function of the adult generation of Leydig cells in mice with Sertoli cell-selective or total ablation of the androgen receptor
De Gendt K, Atanassova N, Tan K, de França L, Parreira G, McKinnell C, Sharpe R, Saunders P, Mason J, Hartung S, Ivell R, Denolet E, Verhoeven G
ENDOCRINOLOGY. 2005;146(9):4117-26.

Long-term outcome in children with relapsed ALL by risk-stratified salvage therapy: results of trial acute lymphoblastic leukemia-relapse study of the Berlin-Frankfurt-Münster Group 87.
Einsiedel H, von Stackelberg A, Hartmann R, Fengler R, Schrappe M, Janka-Schaub G, Mann G, Hählen K, Göbel U, Klingebiel T, Ludwig W, Henze G
J CLIN ONCOL. 2005;23(31):7942-7950.

Immunosuppressive therapy for aplastic anemia in children: a more severe disease predicts better survival.
Führer M, Rampf U, Baumann I, Faldum A, Niemeyer C, Janka-Schaub G, Friedrich W, Ebell W, Borkhardt A, Bender-Goetze C
BLOOD. 2005;106(6):2102-2104.

Non-transferrin-bound iron during blood transfusion cycles in beta-thalassemia major.
Grosse R, Lund U, Caruso V, Fischer R, Janka-Schaub G, Magnano C, Engelhardt R, Dürken M, Nielsen P
ANN NY ACAD SCI. 2005;1054:429-432.

Gene conversions are a common cause of von Willebrand disease.
Gupta P, Adamtziki E, Budde U, Jaiprakash M, Kumar H, Harbeck-Seu A, Kannan M, Oyen F, Obser T, Wedekind I, Saxena R, Schneppenheim R
BRIT J HAEMATOL. 2005;130(5):752-758.

Decreased PARP and procaspase-2 protein levels are associated with cellular drug resistance in childhood acute lymphoblastic leukemia.
Holleman A, Boer d, Monique L, Kazemier K, Beverloo H, Janka-Schaub G, Anne R, Janka-Schaub G, Pieters R
BLOOD. 2005;106(5):1817-1823.

Haematopoietic stem cell transplantation in haemophagocytic lymphohistiocytosis.
Horne A, Janka-Schaub G, Maarten Egeler R, Gadner H, Imashuku S, Ladisch S, Locatelli F, Montgomery S, Webb D, Winiarski J, Filipovich A, Henter J
BRIT J HAEMATOL. 2005;129(5):622-630.

Subtyping of natural killer cell cytotoxicity deficiencies in haemophagocytic lymphohistocytosis provides therapeutic guidance.
Horne A, Zheng C, Lorenz I, Löfstedt M, Montgomery S, Janka-Schaub G, Henter J, Marion Schneider E
BRIT J HAEMATOL. 2005;129(5):658-666.

Amsacrine combined with etoposide and high-dose methylprednisolone as salvage therapy in acute lymphoblastic leukemia in children.
Horstmann M, Hassenpflug W, Udo Z, Escherich G, Janka-Schaub G, Kabisch H
HAEMATOLOGICA. 2005;90(12):1701-1703.

Correlation of bFGF expression in renal cell cancer with clinical and histopathological features by tissue microarray analysis and measurement of serum levels
Horstmann M, Merseburger A, von der Heyde E, Serth J, Wegener G, Mengel M, Feil G, Hennenlotter J, Nagele U, Anastasiadis A, Bokemeyer C, Stenzl A, Kuczyk M
J CANCER RES CLIN. 2005;131(11):715-22.

Insulin-like factor 3 - where are we now?
Ivell R, Hartung S, Anand-Ivell R
ANN NY ACAD SCI. 2005;1041:486-96.

Hemophagocytic lymphohistiocytosis
Janka-Schaub G
HEMATOLOGY. 2005;10 Suppl 1:104-7.

Familial and acquired hemophagocytic lymphohistiocytosis.
Janka-Schaub G, Udo Z
Hematology Am Soc Hematol Educ Program. 2005;82-88.

Interference free and simplyfied liquid chromatography-based determination of thiopurine S-methyltransferase activity in erythrocytes.
Khalil M, Erb N, Khalil P, Escherich G, Janka-Schaub G
J CHROMATOGR B ANALYT TECHNOL BIOMED LIFE SCI. 2005;821(1):105-111.

Sox group E gene expression distinguishes different types and maturational stages of glial cells in developing chick and mouse.
Kordes U, Cheng Y, Scotting P
DEV BRAIN RES. 2005;157(2):209-213.

Identification of genes associated with chemotherapy crossresistance and treatment response in childhood acute lymphoblastic leukemia.
Lugthart S, Cheok M, Boer d, Monique L, Yang W, Holleman A, Cheng C, Pui C, Janka-Schaub G, Janka-Schaub G, Pieters R, Evans W
CANCER CELL. 2005;7(4):375-386.

Hämophilie B (Faktor-IX-Mangel) mit begleitender Faktor-XII-Erniedrigung bei einem Mischlingskater
Lutze G, Kutschmann K, Fürst K, Schneppenheim R
Berliner und Münchener tierärztliche Wochenschrift. 2005;118(5-6):255-60.

Expression of insulin-like factor 3 protein in the rat testis during fetal and postnatal development and in relation to cryptorchidism induced by in utero exposure to di (n-Butyl) phthalate
McKinnell C, Sharpe R, Mahood K, Hallmark N, Scott H, Ivell R, Staub C, Jégou B, Haag F, Koch-Nolte F, Hartung S
ENDOCRINOLOGY. 2005;146(10):4536-44.

Relation between genetic variants of the ataxia telangiectasia-mutated (ATM) gene, drug resistance, clinical outcome and predisposition to childhood T-lineage acute lymphoblastic leukaemia.
Meier M, den Boer M, Hall A, Irving J, Passier M, Minto L, van Wering E, Janka-Schaub G, Pieters R
LEUKEMIA. 2005;19(11):1887-1895.

Long-term treatment with deferiprone in a L1 veteran.
Meo A, Ruggeri A, Rosa L, Angela M, Kordes U, Kordes U, Fischer R
EUR J HAEMATOL. 2005;74(6):523-525.

Langerhans cell histiocytosis in neonates.
Minkov M, Prosch H, Steiner M, Grois N, Pötschger U, Kaatsch P, Janka-Schaub G, Gadner H
PEDIATR BLOOD CANCER. 2005;45(6):802-807.

Decreased plasma concentration of von Willebrand factor antigen (VWF:Ag) in patients with glycogen storage disease type Ia
Mühlhausen C, Schneppenheim R, Budde U, Merkel M, Muschol N, Ullrich K, Santer R
J INHERIT METAB DIS. 2005;28(6):945-50.

The evolving classification of von Willebrand disease
Schneppenheim R
BLOOD COAGUL FIBRIN. 2005;16 Suppl 1:S3-S10.

Angeborenes und erworbenes von-Willebrand-Syndrom
Schneppenheim R, Barthels M, Budde U
HAMOSTASEOLOGIE. 2005;25(4):367-75.

[Viral infections in pediatric cancer patients]
Schuster F, Simon A, Laws H, Beutel K, Groll A, Jäger G, Schuster V
KLIN PADIATR. 2005;217(1):67-84.

[Bacterial infections in pediatric cancer patients]
Simon A, Beutel K, Marklein G, Fleischhack G
KLIN PADIATR. 2005;217(1):17-36.

Targeting FLT3 in primary MLL-gene-rearranged infant acute lymphoblastic leukemia.
Stam R, Boer d, Monique L, Schneider P, Horstmann M, Horstmann M, Beverloo H, van der Voort E, Valsecchi M, de Lorenzo P, Sallan S, Armstrong S, Pieters R
BLOOD. 2005;106(7):2484-2490.

Asparagine synthetase expression is linked with L-asparaginase resistance in TEL-AML1-negative but not TEL-AML1-positive pediatric acute lymphoblastic leukemia.
Stams W, Boer d, Monique L, Holleman A, Appel I, Beverloo H, Janka-Schaub G, Elisabeth R, Janka-Schaub G, Evans W, Pieters R
BLOOD. 2005;105(11):4223-4225.

Effect of the histone deacetylase inhibitor depsipeptide on B-cell differentiation in both TEL-AML1-positive and negative childhood acute lymphoblastic leukemia.
Stams [, Wendy A, Den B, Monique L, Beverloo [, Berna H, Kazemier [, Karin M, Wering v, Elisabeth R, Janka-Schaub G, Gritta E, Pieters [, Rob [
HAEMATOLOGICA. 2005;90(12):1697-1699.

Expression levels of TEL, AML1, and the fusion products TEL-AML1 and AML1-TEL versus drug sensitivity and clinical outcome in t(12;21)-positive pediatric acute lymphoblastic leukemia.
Stams [, Wendy A, Den B, Monique L, Beverloo [, Berna H, Meijerink [, Jules P, Wering v, Elisabeth R, Janka-Schaub G, Gritta E, Pieters [, Rob [
CLIN CANCER RES. 2005;11(8):2974-2980.

Linkage of familial hemophagocytic lymphohistiocytosis (FHL) type-4 to chromosome 6q24 and identification of mutations in syntaxin 11.
Udo Z, Schmidt S, Kasper B, Beutel K, Diler A, Henter J, Kabisch H, Schneppenheim R, Nürnberg P, Janka-Schaub G, Hennies H
HUM MOL GENET. 2005;14(6):827-834.

Ligands for the peroxisome proliferator-activated receptor-gamma have inhibitory effects on growth of human neuroblastoma cells in vitro.
Valentiner U, Carlsson M, Erttmann R, Hildebrandt H, Schumacher U
TOXICOLOGY. 2005;213(1-2):157-168.

2004

Diagnose der thrombotisch-thrombozytopenischen Purpura
Budde U, Angerhaus D, Obser T, Schneppenheim R
HAMOSTASEOLOGIE. 2004;24(1):65-70.

[Diagnosis of thrombotic thrombocytopenic purpura]
Budde U, Angerhaus D, Obser T, Schneppenheim R
HAMOSTASEOLOGIE. 2004;24(1):65-70.

Standardisierte Diagnostik des von-Willebrand-Syndroms
Budde U, Drewke E, Will K, Schneppenheim R
HAMOSTASEOLOGIE. 2004;24(1):12-26.

Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF.
Du J, Widlund H, Horstmann M, Ramaswamy S, Ross K, Huber W, Nishimura E, Golub T, Fisher D
CANCER CELL. 2004;6(6):565-576.

[Thrombotic thrombocytopenic purpura in childhood]
Hassenpflug W, Angerhaus D, Budde U, Obser T, Schneppenheim R
HAMOSTASEOLOGIE. 2004;24(1):71-76.

Thrombotisch-thrombozytopenische Purpura im Kindesalter
Hassenpflug W, Angerhaus D, Budde U, Obser T, Schneppenheim R
HAMOSTASEOLOGIE. 2004;24(1):71-6.

Permanent consequences in Langerhans cell histiocytosis patients: a pilot study from the Histiocyte Society-Late Effects Study Group.
Haupt R, Nanduri V, Calevo M, Bernstrand C, Braier J, Broadbent V, Rey G, McClain K, Janka-Schaub G, Egeler R
PEDIATR BLOOD CANCER. 2004;42(5):438-444.

Secondary cytogenetic aberrations in childhood Philadelphia chromosome positive acute lymphoblastic leukemia are nonrandom and may be associated with outcome.
Heerema N, Harbott J, Galimberti S, Camitta B, Gaynon P, Janka-Schaub G, Kamps W, Basso G, Pui C, Schrappe M, Auclerc M, Carroll A, Conter V, Harrison C, Pullen J, Raimondi S C, Richards S, Riehm H, Sather H, Shuster J, Silverman L, Valsecchi M, Aricò M
LEUKEMIA. 2004;18(4):693-702.

Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment.
Holleman A, Cheok M, Boer d, Monique L, Yang W, Veerman A, Kazemier K, Pei D, Cheng C, Pui C, Janka-Schaub G, Janka-Schaub G, Pieters R, Evans W
NEW ENGL J MED. 2004;351(6):533-542.

Modern management of children with haemophagocytic lymphohistiocytosis.
Janka-Schaub G, Schneider E
BRIT J HAEMATOL. 2004;124(1):4-14.

Gingivitis as probable source of a thoracic actinomycosis due to Actinomyces israelii and Actinobacillus actinomycetemcomitans.
Kordes U, Beutel K, Cachovan G, Schäfer H, Helmke K, Sobottka I
ARCH DIS CHILD. 2004;89(10):895.

Two novel ADAMTS13 gene mutations in thrombotic thrombocytopenic purpura/hemolytic-uremic syndrome (TTP/HUS)
Licht C, Stapenhorst L, Simon T, Budde U, Schneppenheim R, Hoppe B
KIDNEY INT. 2004;66(3):955-8.

Molekulare Genetik des von-Willebrand-Syndroms
Schneppenheim R
HAMOSTASEOLOGIE. 2004;24(1):37-43.

Recombinant expression of mutations causing von Willebrand disease type Normandy: characterization of a combined defect of factor VIII binding and multimerization.
Schneppenheim R, Lenk H, Obser T, Oldenburg J, Oyen F, Schneppenheim S, Schwaab R, Will K, Ulrich B
THROMB HAEMOSTASIS. 2004;92(1):36-41.

Severe ADAMTS-13 deficiency in childhood.
Schneppenheim R, Ulrich B, Hassenpflug W, Obser T
SEMIN HEMATOL. 2004;41(1):83-89.

Multidrug resistance genes in infant acute lymphoblastic leukemia: Ara-C is not a substrate for the breast cancer resistance protein.
Stam [, van Den H, Den B, Ebus [, Janka-Schaub G, Allen [, Pieters R
LEUKEMIA. 2004;18(1):78-83.

A91V is a polymorphism in the perforin gene not causative of an FHLH phenotype.
Udo Z, Beutel K, Weber B, Kabisch H, Schneppenheim R, Janka-Schaub G
BLOOD. 2004;104(6):1910.

In vitro drug-resistance profile in infant acute lymphoblastic leukemia in relation to age, MLL rearrangements and immunophenotype.
Woerden R, Beverloo [, Veerman [, Camitta [, Loonen [, Wering v, Slater [, Harbott J, Den B, Ludwig [, Haas [, Janka-Schaub G, Pieters R
LEUKEMIA. 2004;18(3):521-529.

2003

Patient stratification based on prednisolone-vincristine-asparaginase resistance profiles in children with acute lymphoblastic leukemia.
Den B, Harms [, Pieters R, Kazemier [, Gobel U, Körholz D, Graubner U, Haas [, Jorch N, Spaar [, Kaspers [, Kamps [, Does V, Berg V, Wering V, Janka-Schaub G, Janka-Schaub [
J CLIN ONCOL. 2003;21(17):3262-3268.

MLANA/MART1 and SILV/PMEL17/GP100 are transcriptionally regulated by MITF in melanocytes and melanoma.
Du J, Miller A, Widlund H, Horstmann M, Ramaswamy S, Fisher D
AM J PATHOL. 2003;163(1):333-343.

High-performance liquid chromatographic assay of metabolites of thioguanine and mercaptopurine in capillary blood.
Erb N, Haverland U, Harms D, Escherich G, Janka-Schaub G
J CHROMATOGR B ANALYT TECHNOL BIOMED LIFE SCI. 2003;796(1):87-94.

Sequence analysis of the granulysin and granzyme B genes in familial hemophagocytic lymphohistiocytosis.
Ericson K, Fadeel B, Andersson M, Gudmundsson G, Gürgey A, Yalman N, Janka-Schaub G, Nordenskjöld M, Henter J
HUM GENET. 2003;112(1):98-99.

Thioguanine offers no advantage over mercaptopurine in maintenance treatment of childhood ALL: results of the randomized trial COALL-92.
Harms D, Göbel U, Spaar H, Graubner U, Jorch N, Gutjahr P, Janka-Schaub G
BLOOD. 2003;102(8):2736-2740.

Congenital dyserythropoietic anemia type II: epidemiology, clinical appearance, and prognosis based on long-term observation.
Heimpel H, Anselstetter V, Chrobak L, Denecke J, Einsiedler B, Gallmeier K, Griesshammer A, Marquardt T, Janka-Schaub G, Kron M, Kohne E
BLOOD. 2003;102(13):4576-4581.

Resistance to different classes of drugs is associated with impaired apoptosis in childhood acute lymphoblastic leukemia.
Holleman A, Boer d, Monique L, Janka-Schaub G, Janka-Schaub G, Pieters R
BLOOD. 2003;102(13):4541-4546.

Infantile cobalamin deficiency with cerebral lactate accumulation and sustained choline depletion.
Horstmann M, Neumaier-Probst E, Lukacs Z, Steinfeld R, Ullrich K, Kohlschütter A
NEUROPEDIATRICS. 2003;34(5):261-264.

The molecular basis of cryptorchidism
Ivell R, Hartung S
MOL HUM REPROD. 2003;9(4):175-81.

Cell proliferation is related to in vitro drug resistance in childhood acute leukaemia.
Kaaijk P, Kaspers G, Van Wering E, Broekema G, Loonen A, Hählen K, Schmiegelow K, Janka-Schaub G, Henze G, Creutzig U, Veerman A
BRIT J CANCER. 2003;88(5):775-781.

Effective treatment of hereditary haemochromatosis with desferrioxamine in selected cases.
Nielsen P, Fischer R, Buggisch P, Janka-Schaub G
BRIT J HAEMATOL. 2003;123(5):952-953.

Clinical heterogeneity in childhood acute lymphoblastic leukemia with 11q23 rearrangements.
Pui C, Chessells J, Camitta B, Baruchel A, Biondi A, Boyett J, Carroll A, Eden O, Evans W, Gadner H, Harbott J, Harms D, Harrison C, Harrison P, Heerema N, Janka-Schaub G, Kamps W, Masera G, Pullen J, Raimondi S C, Richards S, Riehm H, Sallan S, Sather H, Shuster J, Silverman L, Valsecchi M, Vilmer E, Zhou Y, Gaynon P, Schrappe M
LEUKEMIA. 2003;17(4):700-706.

Children may not benefit from neuroblastoma screening at 1 year of age. Updated results of the population based controlled trial in Germany.
Schilling F, Spix C, Berthold F, Erttmann R, Sander J, Treuner J, Michaelis J
CANCER LETT. 2003;197(1-2):19-28.

Natural killer deficiency: a minor or major factor in the manifestation of hemophagocytic lymphohistiocytosis?
Schneider E, Lorenz I, Walther P, Janka-Schaub G
J PEDIAT HEMATOL ONC. 2003;25(9):680-683.

von Willebrand factor cleaving protease and ADAMTS13 mutations in childhood TTP.
Schneppenheim R, Ulrich B, Oyen F, Angerhaus D, Aumann V, Drewke E, Hassenpflug W, Häberle J, Kentouche K, Kohne E, Kurnik K, Müller-Wiefel D, Obser T, Santer R, Sykora K
BLOOD. 2003;101(5):1845-1850.

Lead-time and overdiagnosis estimation in neuroblastoma screening.
Spix C, Michaelis J, Berthold F, Erttmann R, Sander J, Schilling F
STAT MED. 2003;22(18):2877-2892.

Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia.
Stam R, Boer d, Monique L, Meijerink J, Ebus M, Peters G, Janka-Schaub G, Janka-Schaub G, Armstrong S, Korsmeyer S, Pieters R
BLOOD. 2003;101(4):1270-1276.

Sensitivity to L-asparaginase is not associated with expression levels of asparagine synthetase in t(12;21)+ pediatric ALL.
Stams [, Wendy A, Den B, Monique L, Beverloo [, Berna H, Meijerink [, Jules P, Stigter [, Rolinda L, Wering v, Elisabeth R, Janka-Schaub G, Gritta E, Slater [, Rosalyn [, Pieters [, Rob [
BLOOD. 2003;101(7):2743-2747.

Rapid LightCycler assay for identification of the perforin codon 374 Trp --> stop mutation in patients and families with hemophagocytic lymphohistiocytosis (HLH).
Udo Z, Kabisch H, Janka-Schaub G, Schneider E
Med Pediatr Oncol. 2003;41(1):26-29.

2% Hämophilie-A-Patienten ohne Mutation im FVIII-Gen
Uen C, Oldenburg J, Schröder J, Brackmann H, Schramm W, Schwaab R, Schneppenheim R, Graw J
HAMOSTASEOLOGIE. 2003;23(1):1-5.

Identification and characterisation of clonal incomplete T-cell-receptor Vdelta2-Ddelta3/Ddelta2-Ddelta3 rearrangements by denaturing high-performance liquid chromatography and subsequent fragment collection
zur Stadt U, Eckert C, Rischewski J, Michael K, Golta S, Müller M, Schneppenheim R, Kabisch H
J CHROMATOGR B ANALYT TECHNOL BIOMED LIFE SCI. 2003;792(2):287-98.

2002

Infant acute lymphoblastic leukemia - combined cytogenetic, immunophenotypical and molecular analysis of 77 cases.
Borkhardt A, Wuchter C, Viehmann S, Pils S, Teigler-Schlegel A, Stanulla M, Zimmermann M, Ludwig W, Janka-Schaub G, Schrappe M, Harbott J
LEUKEMIA. 2002;16(9):1685-1690.

Laboratory diagnosis of congenital von Willebrand disease
Budde U, Drewke E, Mainusch K, Schneppenheim R
SEMIN THROMB HEMOST. 2002;28(2):173-90.

Pretreatment prognostic factors and treatment results in children with hepatoblastoma: a report from the German Cooperative Pediatric Liver Tumor Study HB 94.
Fuchs J, Rydzynski J, Dietrich V, Udo B, Hecker H, Weinel P, Bürger D, Harms D, Erttmann R, Oldhafer K, Mildenberger H
CANCER-AM CANCER SOC. 2002;95(1):172-182.

[Unrelated donor stem cell transplantation in children: low toxicity using a GvHD-prophylaxis regimen with CSA, MTX, metronidazole,iv-immunoglobulin and ATG]
Graf Finckenstein F, Zabelina T, Dürken M, Dahlke J, Kröger N, Krüger W, Janka-Schaub G, Erttmann R, Zander A, Kabisch H
KLIN PADIATR. 2002;214(4):206-211.

In vitro glucocorticoid resistance in childhood leukemia correlates with receptor affinity determined at 37 degrees C, but not with affinity determined at room temperature.
Haarman [, Kaspers [, Pieters R, Rottier [, Den B, Janka-Schaub G, Veerman [
LEUKEMIA. 2002;16(9):1882-1884.

Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation.
Henter J, Samuelsson-Horne A, Aricò M, Egeler R, Elinder G, Filipovich A, Gadner H, Imashuku S, Komp D, Ladisch S, Webb D, Janka-Schaub G
BLOOD. 2002;100(7):2367-2373.

Remission of thrombotic thrombocytopenic purpura in a patient with compound heterozygous deficiency of von Willebrand factor-cleaving protease by infusion of solvent/detergent plasma
Kentouche K, Budde U, Furlan M, Scharfe V, Schneppenheim R, Zintl F
ACTA PAEDIATR. 2002;91(10):1056-9.

11 hemophilia A patients without mutations in the factor VIII encoding gene
Klopp N, Oldenburg J, Uen C, Schneppenheim R, Graw J
THROMB HAEMOSTASIS. 2002;88(2):357-60.

Homozygous Factor V Leiden mutation in sickle cell anaemia.
Kordes U, Janka-Schaub G, Schneppenheim R
BRIT J HAEMATOL. 2002;116(1):236.

In vivo T cell depletion with pretransplant anti-thymocyte globulin reduces graft-versus-host disease without increasing relapse in good risk myeloid leukemia patients after stem cell transplantation from matched related donors.
Kröger N, Zabelina T, Krüger W, Renges H, Stute N, Rischewski J, Sonnenberg S, Ayuk F, Ayuketang Ayuk F, Schade U, Fiegel H, Erttmann R, Löliger C, Zander A
BONE MARROW TRANSPL. 2002;29(8):683-689.

Long-term follow-up of allogeneic stem cell transplantation in patients with severe aplastic anemia after conditioning with cyclophosphamide plus antithymocyte globulin.
Kröger N, Zabelina T, Renges H, Krüger W, Kordes U, Rischewski J, Schrum J, Horstmann M, Ayuketang Ayuk F, Erttmann R, Kabisch H, Zander A
ANN HEMATOL. 2002;81(11):627-631.

Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability.
McGill G, Horstmann M, Widlund H, Du J, Motyckova G, Nishimura E, Lin Y, Ramaswamy S, Avery W, Ding H, Jordan S, Jackson I, Korsmeyer S, Golub T, Fisher D
CELL. 2002;109(6):707-718.

[SQUID-biosusceptometry in iron overloaded patients with hematologic diseases]
Nielsen P, Kordes U, Fischer R, Engelhardt R, Janka-Schaub G
KLIN PADIATR. 2002;214(4):218-222.

In vitro drug resistance profile of Philadelphia positive acute lymphoblastic leukemia is heterogeneous and related to age: a report of the Dutch and German Leukemia Study Groups.
Ramakers-van Woerden N, Pieters R, Hoelzer D, Slater R, den Boer M, Loonen A, Harbott J, Janka-Schaub G, Ludwig W, Ossenkoppele G, van Wering E, Veerman A
Med Pediatr Oncol. 2002;38(6):379-386.

Neuroblastoma screening at one year of age.
Schilling F, Spix C, Berthold F, Erttmann R, Fehse N, Hero B, Klein G, Sander J, Schwarz K, Treuner J, Zorn U, Michaelis J
NEW ENGL J MED. 2002;346(14):1047-1053.

Hemophagocytic lymphohistiocytosis is associated with deficiencies of cellular cytolysis but normal expression of transcripts relevant to killer-cell-induced apoptosis.
Schneider E, Lorenz I, Müller-Rosenberger M, Steinbach G, Kron M, Janka-Schaub G
BLOOD. 2002;100(8):2891-2898.

Prenatal diagnosis of perforin gene mutations in familial hemophagocytic lymphohistiocytosis (FHLH).
Udo Z, Pruggmayer M, Jung H, Henter J, Schneider M, Kabisch H, Janka-Schaub G
PRENATAL DIAG. 2002;22(1):80-81.

Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor
Widlund H, Horstmann M, Price E, Cui J, Lessnick S, Wu M, He X, Fisher D
J CELL BIOL. 2002;158(6):1079-87.

Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome.
Zwaan C, Kaspers G, Pieters R, Hählen K, Janka-Schaub G, Zantwijk v, Christina H, Huismans D, de Vries E, Rots M, Peters G, Jansen G, Creutzig U, Veerman A
BLOOD. 2002;99(1):245-251.

2001

Familial hemophagocytic lymphohistiocytosis: how late can the onset be?
Allen M, De Fusco C, Legrand F, Clementi R, Conter V, Danesino C, Janka-Schaub G, Aricò M
HAEMATOLOGICA. 2001;86(5):499-503.

Six novel mutations in the PRF1 gene in children with haemophagocytic lymphohistiocytosis.
Clementi R, Zur Stadt U, Savoldi G, Varoitto S, Conter V, De Fusco C, Notarangelo L, Schneider M, Klersy C, Janka-Schaub G, Danesino C, Aricò M
J MED GENET. 2001;38(9):643-646.

Bone marrow transplantation in hemophagocytic lymphohistiocytosis.
Dürken M, Finckenstein F, Janka-Schaub G
LEUKEMIA LYMPHOMA. 2001;41(1-2):89-95.

Spectrum of perforin gene mutations in familial hemophagocytic lymphohistiocytosis.
Göransdotter Ericson K, Fadeel B, Nilsson-Ardnor S, Söderhäll C, Samuelsson A, Janka G, Schneider M, Gürgey A, Yalman N, Révész T, Egeler R, Jahnukainen K, Storm-Mathiesen I, Haraldsson A, Poole J, Janka-Schaub G, Nordenskjöld M, Henter J
AM J HUM GENET. 2001;68(3):590-597.

A fludarabine-based dose-reduced conditioning regimen followed by allogeneic stem cell transplantation from related or unrelated donors in patients with myelodysplastic syndrome.
Kröger N, Schetelig J, Zabelina T, Krüger W, Renges H, Stute N, Schrum J, Kabisch H, Siegert W, Zander A
BONE MARROW TRANSPL. 2001;28(7):643-647.

Anti-thymocyte-globulin as part of the preparative regimen prevents graft failure and severe graft versus host disease (GvHD) in allogeneic stem cell transplantation from unrelated donors.
Kröger N, Zabelina T, Krüger W, Renges H, Stute N, Dürken M, Graf von Finkenstein F, Erttmann R, Kabisch H, Schafhausen P, Jaburg N, Löliger C, Zander A
ANN HEMATOL. 2001;80(4):209-215.

Patient cytomegalovirus seropositivity with or without reactivation is the most important prognostic factor for survival and treatment-related mortality in stem cell transplantation from unrelated donors using pretransplant in vivo T-cell depletion with anti-thymocyte globulin.
Kröger N, Zabelina T, Krüger W, Renges H, Stute N, Schrum J, Kabisch H, Schafhausen P, Jaburg N, Löliger C, Schäfer P, Hinke A, Zander A
BRIT J HAEMATOL. 2001;113(4):1060-1071.

Linking osteopetrosis and pycnodysostosis
Motyckova G, Weilbaecher K, Horstmann M, Rieman D, Fisher D, Fisher D
P NATL ACAD SCI USA. 2001;98(10):5798-803.

Linking osteopetrosis and pycnodysostosis: regulation of cathepsin K expression by the microphthalmia transcription factor family.
Motyckova G, Weilbaecher K, Horstmann M, Rieman D, Fisher D, Fisher D
P NATL ACAD SCI USA. 2001;98(10):5798-5803.

Familial Williams-Beuren syndrome showing varying clinical expression
Pankau R, Siebert R, Kautza M, Schneppenheim R, Gosch A, Wessel A, Partsch C
Am J Med Genet. 2001;98(4):324-9.

Localized Ewing tumor of bone: final results of the cooperative Ewing's Sarcoma Study CESS 86.
Paulussen M, Ahrens S, Dunst J, Winkelmann W, Exner G, Kotz R, Amann G, Dockhorn-Dworniczak B, Harms D, Müller-Weihrich S, Welte K, Kornhuber B, Janka-Schaub G, Göbel U, Treuner J, Voûte P, Zoubek A, Gadner H, Jürgens H
J CLIN ONCOL. 2001;19(6):1818-1829.

In vitro drug resistance and prognostic impact of p16INK4A/P15INK4B deletions in childhood T-cell acute lymphoblastic leukaemia.
Ramakers-van Woerden N, Pieters R, Slater R, Loonen A, Beverloo H, van Drunen E, Heyman M, Moreno T, Rots M, van Wering E, Kamps W, Janka-Schaub G, Veerman A
BRIT J HAEMATOL. 2001;112(3):680-690.

Screening strategies for a highly polymorphic gene
Rischewski J, Schneppenheim R
Journal of biochemical and biophysical methods. 2001;47(1-2):53-64.

Expression and characterization of von Willebrand factor dimerization defects in different types of von Willebrand disease.
Schneppenheim R, Budde U, Obser T, Brassard J, Mainusch K, Ruggeri Z, Schneppenheim S, Schwaab R, Oldenburg J
BLOOD. 2001;97(7):2059-2066.

A molecular approach to the classification of von Willebrand disease
Schneppenheim R, Budde U, Ruggeri Z
BEST PRACT RES CL HA. 2001;14(2):281-98.

Short-pulse B-non-Hodgkin lymphoma-type chemotherapy is efficacious treatment for pediatric anaplastic large cell lymphoma: a report of the Berlin-Frankfurt-Münster Group Trial NHL-BFM 90.
Seidemann K, Tiemann M, Schrappe M, Yakisan E, Simonitsch I, Janka-Schaub G, Dörffel W, Zimmermann M, Mann G, Gadner H, Parwaresch R, Riehm H, Reiter A
BLOOD. 2001;97(12):3699-3706.

Quantification and facilitated comparison of von Willebrand factor multimer patterns by densitometry
Studt J, Budde U, Schneppenheim R, Eisert R, von Depka Prondzinski M, Ganser A, Barthels M
AM J CLIN PATHOL. 2001;116(4):567-74.

Successful treatment of Pseudomonas aeruginosa respiratory tract infection with a sugar solution--a case report on a lectin based therapeutic principle
von Bismarck P, Schneppenheim R, Schumacher U
KLIN PADIATR. 2001;213(5):285-7.

MRD at the end of induction therapy in childhood acute lymphoblastic leukemia: outcome prediction strongly depends on the therapeutic regimen.
Zur Stadt U, Harms D, Schlüter S, Schrappe M, Goebel U, Spaar H, Janka-Schaub G, Kabisch H
LEUKEMIA. 2001;15(2):283-285.

Denaturing HPLC for identification of clonal T-cell receptor gamma rearrangements in newly diagnosed acute lymphoblastic leukemia
zur Stadt U, Rischewski J, Schneppenheim R, Kabisch H
CLIN CHEM. 2001;47(11):2003-11.

2000

Outcome of treatment in children with Philadelphia chromosome-positive acute lymphoblastic leukemia.
Aricò M, Valsecchi M, Camitta B, Schrappe M, Chessells J, Baruchel A, Gaynon P, Silverman L, Janka-Schaub G, Kamps W, Pui C, Masera G
NEW ENGL J MED. 2000;342(14):998-1006.

An additional unique candidate mutation (G2470A; M740I) in the original families with von Willebrand disease type 2 M Vicenza and the G3864A (R1205H) mutation
Castaman G, Missiaglia E, Federici A, Schneppenheim R, Rodeghiero F
THROMB HAEMOSTASIS. 2000;84(2):350-1.

Paraneoplastic cerebellar degeneration in pediatric Hodgkin disease
Hahn A, Claviez A, Brinkmann G, Altermatt H, Schneppenheim R, Stephani U
NEUROPEDIATRICS. 2000;31(1):42-4.

Co-operative study group for childhood acute lymphoblastic leukemia (COALL): long-term follow-up of trials 82, 85, 89 and 92.
Harms D, Janka-Schaub G
LEUKEMIA. 2000;14(12):2234-2239.

Hereditary fructose intolerance and alpha(1) antitrypsin deficiency
Hillebrand G, Schneppenheim R, Oldigs H, Santer R
Archives of disease in childhood. 2000;83(1):72-3.

Transcription factor NF-kappaB is constitutively activated in acute lymphoblastic leukemia cells.
Kordes U, Krappmann D, Heissmeyer V, Ludwig W, Scheidereit C
LEUKEMIA. 2000;14(3):399-402.

Dose-dependent effect of etoposide in combination with busulfan plus cyclophosphamide as conditioning for stem cell transplantation in patients with acute myeloid leukemia.
Kröger N, Zabelina T, Sonnenberg S, Krüger W, Renges H, Stute N, Finkenstein F, Mayer U, Holstein K, Fiedler W, Colberg H, Sonnen R, Kuse R, Braumann D, Metzner B, Del Valle F, Erttmann R, Kabisch H, Zander A
BONE MARROW TRANSPL. 2000;26(7):711-716.

Using SQUID biomagnetic liver susceptometry in the treatment of thalassemia and other iron loading diseases.
Nielsen P, Engelhardt R, Duerken M, Janka-Schaub G, Fischer R
Transfus Sci. 2000;23(3):257-258.

Williams-Beuren syndrome 35 years after the diagnosis in one of the first Beuren patients
Pankau R, Partsch C, Gosch A, Siebert R, Schneider M, Schneppenheim R, Winter M, Wessel A
Am J Med Genet. 2000;91(4):322-4.

TEL/AML1 gene fusion is related to in vitro drug sensitivity for L-asparaginase in childhood acute lymphoblastic leukemia.
Ramakers-van Woerden N, Pieters R, Loonen A, Hubeek I, van Drunen E, Beverloo H, Slater R, Harbott J, Seyfarth J, van Wering E, Hählen K, Schmiegelow K, Janka-Schaub G, Veerman A
BLOOD. 2000;96(3):1094-1099.

The common deletion 657del5 in the Nibrin gene is not a major risk factor for B or T cell non-Hodgkin lymphoma in a pediatric population.
Rischewski J, Bismarck P, Kabisch H, Janka-Schaub G, Obser T, Schneppenheim R
LEUKEMIA. 2000;14(8):1528-1529.

A heterozygous frameshift mutation in the Fanconi anemia C gene in familial T-ALL and secondary malignancy
Rischewski J, Clausen H, Leber V, Niemeyer C, Ritter J, Schindler D, Schneppenheim R
KLIN PADIATR. 2000;212(4):174-6.

Methotrexate resistance in relapsed childhood acute lymphoblastic leukaemia.
Rots M, Pieters R, Peters G, Noordhuis P, Van Zantwijk C, Henze G, Janka-Schaub G, Veerman A, Jansen G
BRIT J HAEMATOL. 2000;109(3):629-634.

Population-based and controlled study to evaluate neuroblastoma screening at one year of age in Germany: interim results.
Schilling F, Berthold F, Erttmann R, Michaelis J, Spix C, Sander J, Schwarz K, Treuner J
Med Pediatr Oncol. 2000;35(6):701-704.

Von Willebrand Disease type 2M "Vicenza" in Italian and German patients
Schneppenheim R, Federici A, Budde U, Castaman G, Drewke E, Krey S, Mannucci P, Riesen G, Rodeghiero F, Zieger B, Zimmermann R
THROMB HAEMOSTASIS. 2000;83(1):136-40.

Long-term results of large prospective trials in childhood acute lymphoblastic leukemia.
Schrappe M, Camitta B, Pui C, Eden T, Gaynon P, Gustafsson G, Janka-Schaub G, Kamps W, Masera G, Sallan S, Tsuchida M, Vilmer E
LEUKEMIA. 2000;14(12):2193-2194.

c-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi.
Wu M, Hemesath T, Takemoto C, Horstmann M, Wells A, Price E, Fisher D, Fisher D
GENE DEV. 2000;14(3):301-312.

[Minimal residual disease analysis in acute lymphoblastic leukemia of childhood within the framework of COALL Study: results of an induction therapy without asparaginase]
Zur Stadt U, Harms D, Schlüter S, Jorch N, Spaar H, Nürnberger W, Völpel S, Gutjahr P, Schrappe M, Janka-Schaub G, Kabisch H
KLIN PADIATR. 2000;212(4):169-173.

Cellular drug resistance profiles in childhood acute myeloid leukemia: differences between FAB types and comparison with acute lymphoblastic leukemia.
Zwaan C, Kaspers G, Pieters R, Ramakers-Van Woerden N, den Boer M, Wünsche R, Rottier M, Hählen K, van Wering E, Janka-Schaub G, Creutzig U, Veerman A
BLOOD. 2000;96(8):2879-2886.

1999

Intracerebral hemorrhage as a late complication after CNS treatment of childhood lymphoma
Claviez A, Neubauer B, Link J, Schneppenheim R
KLIN PADIATR. 1999;210(6):406-8.

Human natural immunoglobulin M antibodies induce apoptosis of human neuroblastoma cells by binding to a Mr 260,000 antigen.
David K, Ollert M, Vollmert C, Heiligtag S, Eickhoff B, Erttmann R, Bredehorst R, Vogel C
CANCER RES. 1999;59(15):3768-3775.

Myeloid antigen co-expression in childhood acute lymphoblastic leukaemia: relationship with in vitro drug resistance.
Den Boer M, Kapaun P, Pieters R, Kazemier K, Janka-Schaub G, Veerman A
BRIT J HAEMATOL. 1999;105(4):876-882.

Different expression of glutathione S-transferase alpha, mu and pi in childhood acute lymphoblastic and myeloid leukaemia.
Den Boer M, Pieters R, Kazemier K, Janka-Schaub G, Henze G, Creutzig U, Kaspers G, Kearns P, Hall A, Pearson A, Veerman A
BRIT J HAEMATOL. 1999;104(2):321-327.

Relationship between the intracellular daunorubicin concentration, expression of major vault protein/lung resistance protein and resistance to anthracyclines in childhood acute lymphoblastic leukemia.
Den Boer M, Pieters R, Kazemier K, Janka-Schaub G, Henze G, Veerman A
LEUKEMIA. 1999;13(12):2023-2030.

Linkage of familial hemophagocytic lymphohistiocytosis to 10q21-22 and evidence for heterogeneity.
Dufourcq-Lagelouse R, Jabado N, Le Deist F, Stéphan J, Souillet G, Bruin M, Vilmer E, Schneider M, Janka-Schaub G, Fischer A, de Saint Basile G
AM J HUM GENET. 1999;64(1):172-179.

Improved outcome in haemophagocytic lymphohistiocytosis after bone marrow transplantation from related and unrelated donors
Dürken M, Horstmann M, Bieling P, Erttmann R, Kabisch H, Löliger C, Schneider E, Hellwege H, Krüger W, Kröger N, Zander A, Janka G
BRIT J HAEMATOL. 1999;106(4):1052-8.

Improved outcome in haemophagocytic lymphohistiocytosis after bone marrow transplantation from related and unrelated donors: a single-centre experience of 12 patients.
Dürken M, Horstmann M, Bieling P, Erttmann R, Kabisch H, Löliger C, Schneider E, Hellwege H, Krüger W, Kröger N, Zander A, Janka-Schaub G
BRIT J HAEMATOL. 1999;106(4):1052-1058.

Assessment of iron stores in children with transfusion siderosis by biomagnetic liver susceptometry.
Fischer R, Tiemann C, Engelhardt R, Nielsen P, Dürken M, Gabbe E, Janka-Schaub G
AM J HEMATOL. 1999;60(4):289-299.

Analysis of treatment efficiency of carboplatin and etoposide in combination with radical surgery in advanced and recurrent childhood hepatoblastoma: a report of the German Cooperative Pediatric Liver Tumor Study HB 89 and HB 94.
Fuchs J, Bode U, von Schweinitz D, Weinel P, Erttmann R, Harms D, Mildenberger H
KLIN PADIATR. 1999;211(4):305-309.

[In vitro drug resistance as independent prognostic factor in the study COALL-O5-92 Treatment of childhood acute lymphoblastic leukemia; two-tiered classification of treatments based on accepted risk criteria and drug sensitivity profiles in study COALL-06-97]
Janka-Schaub G, Harms D, den Boer M, Veerman A, Pieters R
KLIN PADIATR. 1999;211(4):233-238.

Molecular mechanisms of constitutive NF-kappaB/Rel activation in Hodgkin/Reed-Sternberg cells.
Krappmann D, Emmerich F, Kordes U, Scharschmidt E, Dörken B, Scheidereit C
ONCOGENE. 1999;18(4):943-953.

Early infections in patients undergoing bone marrow or blood stem cell transplantation--a 7 year single centre investigation of 409 cases.
Krüger W, Rüssmann B, Kröger N, Salomon C, Ekopf N, Elsner H, Kaulfers P, Mack D, Fuchs N, Dürken M, Kabisch H, Erttmann R, Zander A
BONE MARROW TRANSPL. 1999;23(6):589-597.

A classification based on T cell selection-related phenotypes identifies a subgroup of childhood T-ALL with favorable outcome in the COALL studies.
Niehues T, Kapaun P, Harms D, Burdach S, Kramm C, Körholz D, Janka-Schaub G, Göbel U
LEUKEMIA. 1999;13(4):614-617.

Longitudinal evaluation of growth, puberty, and bone maturation in children with Williams syndrome
Partsch C, Dreyer G, Gosch A, Winter M, Schneppenheim R, Wessel A, Pankau R
J PEDIATR-US. 1999;134(1):82-9.

A 2-year-old boy with recurrent severe bleeding
Rauch R, Budde U, Schneppenheim R, Ries M, Girisch M, Klinge J
EUR J PEDIATR. 1999;158 Suppl 3:S171-3.

Circumvention of methotrexate resistance in childhood leukemia subtypes by rationally designed antifolates.
Rots M, Pieters R, Peters G, van Zantwijk C, Mauritz R, Noordhuis P, Willey J, Hählen K, Creutzig U, Janka-Schaub G, Kaspers G, Veerman A, Jansen G
BLOOD. 1999;94(9):3121-3128.

[Natural human IgM-antibodies in neuroblastoma therapy: preliminary findings of a phase I/II clinical trial]
Schmitt C, David K, Hiller J, Schrum J, Bredehorst R, Vogel C, Löliger C, Erttmann R
KLIN PADIATR. 1999;211(4):314-318.

Use of a five-agent GVHD prevention regimen in recipients of unrelated donor marrow.
Zander A, Zabelina T, Kröger N, Renges H, Krüger W, Löliger C, Dürken M, Stockschläder M, de Wit M, Wacker-Backhaus G, Bielack S, Jaburg N, Rüssmann B, Erttmann R, Kabisch H
BONE MARROW TRANSPL. 1999;23(9):889-893.

1998

The modulating effect of PSC 833, cyclosporin A, verapamil and genistein on in vitro cytotoxicity and intracellular content of daunorubicin in childhood acute lymphoblastic leukemia.
den Boer M, Pieters R, Kazemier K, Janka-Schaub G, Henze G, Veerman A
LEUKEMIA. 1998;12(6):912-920.

Relationship between major vault protein/lung resistance protein, multidrug resistance-associated protein, P-glycoprotein expression, and drug resistance in childhood leukemia.
den Boer M, Pieters R, Kazemier K, Rottier M, Zwaan C, Kaspers G, Janka-Schaub G, Henze G, Creutzig U, Scheper R, Veerman A
BLOOD. 1998;91(6):2092-2098.

[Treatment of hemophagocytic lymphohistiocytosis, HLH, with bone marrow transplantation]
Dürken M, Schneider E, Blütters-Sawatzki R, Stollmann-Gibbels B, Janka-Schaub G, Bretz R, Körholz D, Probst E, Holsten-Griffin H, Harps E, Zander A, Janka G
KLIN PADIATR. 1998;210(4):180-184.

Pharmacokinetics and metabolism of thiopurines in children with acute lymphoblastic leukemia receiving 6-thioguanine versus 6-mercaptopurine.
Erb N, Harms D, Janka-Schaub G
CANCER CHEMOTH PHARM. 1998;42(4):266-272.

10 years' neuroblastoma screening in Europe: preliminary results of a clinical and biological review from the Study Group for Evaluation of Neuroblastoma Screening in Europe (SENSE).
Erttmann R, Tafese T, Berthold F, Kerbl R, Mann J, Parker L, Schilling F, Ambros P, Christiansen H, Favrot M, Kabisch H, Hero B, Philip T
EUR J CANCER. 1998;34(9):1391-1397.

Relapse and clonal disease in children with aplastic anemia (AA) after immunosuppressive therapy (IST): the SAA 94 experience. German/Austrian Pediatric Aplastic Anemia Working Group.
Führer M, Burdach S, Ebell W, Gadner H, Haas R, Harbott J, Janka-Schaub G, Klingebiel T, Kremens B, Niemeyer C, Rampf U, Reiter A, Ritter J, Schulz A, Walther U, Zeidler C, Bender-Götze C
KLIN PADIATR. 1998;210(4):173-179.

Familial hemophagocytic lymphohistiocytosis. Primary hemophagocytic lymphohistiocytosis.
Henter J, Aricò M, Janka-Schaub G, Imashuku S, Janka G
HEMATOL ONCOL CLIN N. 1998;12(2):417-433.

Ins405AsnPro mutation in the von Willebrand factor propeptide in recessive type 2A (IIC) von Willebrand's disease
Holmberg L, Karpman D, Isaksson C, Kristoffersson A, Lethagen S, Schneppenheim R
THROMB HAEMOSTASIS. 1998;79(4):718-22.

Infection- and malignancy-associated hemophagocytic syndromes. Secondary hemophagocytic lymphohistiocytosis.
Janka G, Imashuku S, Janka-Schaub G, Schneider M, Henter J
HEMATOL ONCOL CLIN N. 1998;12(2):435-444.

Treatment and long-term outcome of pineal nongerminomatous germ cell tumors.
Knappe U, Bentele K, Horstmann M, Herrmann H
PEDIATR NEUROSURG. 1998;28(5):241-245.

Busulfan, cyclophosphamide and etoposide as high-dose conditioning therapy in patients with malignant lymphoma and prior dose-limiting radiation therapy.
Kröger N, Hoffknecht M, Hänel M, Krüger W, Zeller W, Stockschläder M, de Wit M, Weh H, Kabisch H, Erttmann R, Zander A
BONE MARROW TRANSPL. 1998;21(12):1171-1175.

Intensified conditioning regimen in bone marrow transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia.
Kröger N, Krüger W, Wacker-Backhaus G, Hegewisch-Becker S, Stockschläder M, Fuchs N, Rüssmann B, Renges H, Dürken M, Bielack S, de Wit M, Schuch G, Bartels H, Braumann D, Kuse R, Kabisch H, Erttmann R, Zander A
BONE MARROW TRANSPL. 1998;22(11):1029-1033.

Relation between age, immunophenotype and in vitro drug resistance in 395 children with acute lymphoblastic leukemia--implications for treatment of infants.
Pieters R, den Boer M, Durian M, Janka-Schaub G, Schmiegelow K, Kaspers G, van Wering E, Veerman A
LEUKEMIA. 1998;12(9):1344-1348.

Bilateral renal vein thrombosis and venous sinus thrombosis in a neonate with factor V mutation (FV Leiden)
Pohl M, Zimmerhackl L, Heinen F, Sutor A, Schneppenheim R, Brandis M
J PEDIATR-US. 1998;132(1):159-61.

alpha-Melanocyte-stimulating hormone signaling regulates expression of microphthalmia, a gene deficient in Waardenburg syndrome.
Price E, Horstmann M, Wells A, Weilbaecher K, Takemoto C, Landis M, Fisher D
J BIOL CHEM. 1998;273(49):33042-33047.

Detection of hyperdiploid karyotypes (>50 chromosomes) in childhood acute lymphoblastic leukemia (ALL) using fluorescence in situ hybridization (FISH).
Ritterbach J, Hiddemann W, Beck J, Schrappe M, Janka-Schaub G, Ludwig W, Harbott J, Lampert F
LEUKEMIA. 1998;12(3):427-433.

Age-resolving osteopetrosis
Weilbaecher K, Hershey C, Takemoto C, Horstmann M, Hemesath T, Tashjian A, Fisher D
J EXP MED. 1998;187(5):775-85.

Age-resolving osteopetrosis: a rat model implicating microphthalmia and the related transcription factor TFE3.
Weilbaecher K, Hershey C, Takemoto C, Horstmann M, Hemesath T, Tashjian A, Fisher D
J EXP MED. 1998;187(5):775-785.

1997

Thiopurine biology and pharmacology.
Aarbakke J, Janka-Schaub G, Elion G
TRENDS PHARMACOL SCI. 1997;18(1):3-7.

Transcription of tal-1, a putative oncogene playing an important role in childhood T-ALL, can be shown in normal peripheral blood cells by a highly sensitive RT-PCR assay.
Anderegg B, Horstmann M, Ernst M, Kabisch H
PEDIATR HEMAT ONCOL. 1997;14(4):349-358.

Effects of anti-tal-1 oligodeoxynucleotides in T-ALL cell lines.
Anderegg B, Horstmann M, Kabisch H
CANCER GENE THER. 1997;4(2):84-90.

Expression of a 260 kDa neuroblastoma surface antigen, the target of cytotoxic natural human IgM: correlation to MYCN amplification and effects of retinoic acid.
David K, Ehrhardt A, Ollert M, Erttmann R, Bredehorst R, Vogel C
EUR J CANCER. 1997;33(12):1937-1941.

Contemporary classification of histiocytic disorders. The WHO Committee On Histiocytic/Reticulum Cell Proliferations. Reclassification Working Group of the Histiocyte Society.
Favara B, Feller A, Pauli M, Jaffe E, Weiss L, Arico M, Bucsky P, Egeler R, Elinder G, Gadner H, Gresik M, Henter J, Imashuku S, Janka-Schaub G, Jaffe R, Ladisch S, Nezelof C, Pritchard J
Med Pediatr Oncol. 1997;29(3):157-166.

Factors influencing the haematological recovery after allogeneic bone marrow transplantation in leukaemia patients treated with methotrexate-containing GVHD prophylaxis: a single-centre experience.
Hassan H, Krog C, Stockschläder M, Schleimer B, Zeller W, Krüger W, Erttmann R, Zander A
ANTICANCER RES. 1997;17(1):589-599.

Factors influencing haematological recovery after allogeneic bone marrow transplantation in leukaemia patients treated with methotrexate-containing GVHD prophylaxis. A single-centre experience.
Hassan H, Krog C, Stockschläder M, Zeller W, Krüger W, Erttmann R, Zander A
SUPPORT CARE CANCER. 1997;5(4):299-306.

HLH-94: a treatment protocol for hemophagocytic lymphohistiocytosis. HLH study Group of the Histiocyte Society.
Henter J, Aricò M, Egeler R, Elinder G, Favara B, Filipovich A, Gadner H, Imashuku S, Janka-Schaub G, Komp D, Ladisch S, Webb D
Med Pediatr Oncol. 1997;28(5):342-347.

Late manifestation of diabetes insipidus in "pure" cutaneous Langerhans cell histiocytosis.
Hoeger P, Janka-Schaub G, Mensing H
EUR J PEDIATR. 1997;156(7):524-527.

Frequent reduction or loss of DCC gene expression in human osteosarcoma.
Horstmann M, Pösl M, Scholz R, Anderegg B, Simon P, Baumgaertl K, Delling G, Kabisch H
BRIT J CANCER. 1997;75(9):1309-1317.

Antimycotic therapy with liposomal amphotericin-B for patients undergoing bone marrow or peripheral blood stem cell transplantation.
Krüger W, Stockschläder M, Sobottka I, Betker R, De Wit M, Kröger N, Grimm J, Arland M, Fiedler W, Erttmann R, Zander A
LEUKEMIA LYMPHOMA. 1997;24(5-6):491-499.

APC resistance in childhood thromboembolism
Nowak-Göttl U, Schneppenheim R, Vielhaber H
SEMIN THROMB HEMOST. 1997;23(3):253-8.

Arginine506 to glutamin mutation in the factor V gene in infancy and childhood: evidence of fibrinolytic impairment
Nowak-Göttl U, Vielhaber H, Grohmann J, Schneppenheim R, Koch H
EUR J PEDIATR. 1997;156(3):195-8.

Mechanisms of in vivo anti-neuroblastoma activity of human natural IgM.
Ollert M, David K, Vollmert C, Juhl H, Erttmann R, Bredehorst R, Vogel C
EUR J CANCER. 1997;33(12):1942-1948.

Efficiency and toxicity of ifosfamide, cisplatin and doxorubicin in the treatment of childhood hepatoblastoma. Study Committee of the Cooperative Paediatric Liver Tumour Study HB89 of the German Society for Paediatric Oncology and Haematology.
von Schweinitz D, Byrd D, Hecker H, Weinel P, Bode U, Bürger D, Erttmann R, Harms D, Mildenberger H
EUR J CANCER. 1997;33(8):1243-1249.

High dose chemotherapy with busulfan, cyclophosphamide, and etoposide as conditioning regimen for allogeneic bone marrow transplantation for patients with acute myeloid leukemia in first complete remission.
Zander A, Berger C, Kröger N, Stockshläder M, Krüger W, Horstmann M, Grimm J, Zeller W, Kabisch H, Erttmann R, Schönrock P, Kuse R, Braumann D, Illiger H, Fiedler W, de Witt M, Hossfeld K, Weh H
CLIN CANCER RES. 1997;3(12 Pt 2):2671-2675.

1996

Hemophagocytic lymphohistiocytosis. Report of 122 children from the International Registry. FHL Study Group of the Histiocyte Society.
Aricò M, Janka G, Fischer A, Henter J, Blanche S, Janka-Schaub G, Martinetti M, Rusca M
LEUKEMIA. 1996;10(2):197-203.

Prevalence of factor V Leiden in children with thrombo-embolism
Aschka I, Aumann V, Bergmann F, Budde U, Eberl W, Eckhof-Donovan S, Krey S, Nowak-Göttl U, Schobess R, Sutor A, Wendisch J, Schneppenheim R
EUR J PEDIATR. 1996;155(12):1009-14.

The recurrence patterns of stages I, II and III neuroblastoma: experience with 77 relapsing patients.
Berthold F, Hero B, Breu H, Christiansen H, Erttmann R, Gnekow A, Herrmann F, Klingebiel T, Lampert F, Müller-Weihrich S, Weinel P
ANN ONCOL. 1996;7(2):183-187.

Impact of scheduling on toxicity and clinical efficacy of doxorubicin: what do we know in the mid-nineties?
Bielack S, Erttmann R, Kempf-Bielack B, Winkler K
EUR J CANCER. 1996;32(10):1652-1660.

Peripheral blast counts at diagnosis of late isolated bone marrow relapse of childhood acute lymphoblastic leukemia predict response to salvage chemotherapy and outcome. Berlin-Frankfurt-Münster Relapse Study Group.
Bührer C, Hartmann R, Fengler R, Rath B, Schrappe M, Janka-Schaub G, Henze G
J CLIN ONCOL. 1996;14(10):2812-2817.

Hepatopathie bei Patienten mit Neuroblastom Stadium 4S
Claviez A, Hero B, Schneppenheim R, Berthold F
KLIN PADIATR. 1996;208(4):221-8.

Growth arrest of solid human neuroblastoma xenografts in nude rats by natural IgM from healthy humans.
David K, Ollert M, Juhl H, Vollmert C, Erttmann R, Vogel C, Bredehorst R
NAT MED. 1996;2(6):686-689.

Naturally occurring humoral cytotoxicity against neuroblastoma (NB) cells in healthy persons and NB patients.
Erttmann R, Schmitt C, Ollert M, David K, Bredehorst R, Vogel C
PEDIATR HEMAT ONCOL. 1996;13(6):545-548.

Comparison of the diagnostic and prognostic value of biological markers in neuroblastoma. Proposal for a common methodology of analysis. SENSE group.
Favrot M, Ambros P, Schilling F, Frappaz D, Combaret V, Berthold F, Dominici C, Erttmann R, Esteve J, Jenkner A, Kerbl R, Mann J, Mathieu P, Parker L, Powell J, Philip T
ANN ONCOL. 1996;7(6):607-611.

Pharmacokinetics of the 5HT3 receptor antagonist tropisetron in children.
Gaedicke G, Erttmann R, Henze G, Hartmann W, Drechsler S, Grass P, Faerber L, Kutz K
PEDIATR HEMAT ONCOL. 1996;13(5):405-416.

MLL/ENL fusion in congenital acute lymphoblastic leukemia with a unique t(11;18;19).
Horstmann M, Argyriou-Tirita A, Borkhardt A, Kabisch H, Kapaun P, Winkler K, Haas O
CANCER GENET CYTOGEN. 1996;88(2):103-109.

Early toxicity of intensified conditioning with etoposide combined with total body irradiation/cyclophosphamide or busulfan/cyclophosphamide in children undergoing autologous or allogeneic bone marrow transplantation.
Horstmann M, Kroschke G, Stockschläder M, Betker R, Krüger W, Erttmann R, Kabisch H, Zander A
PEDIATR HEMAT ONCOL. 1996;13(1):45-53.

Randomized comparison of rotational chemotherapy in high-risk acute lymphoblastic leukaemia of childhood--follow up after 9 years. Coall Study Group.
Janka-Schaub G, Harms D, Goebel U, Graubner U, Gutjahr P, Haas R, Juergens H, Spaar H, Winkler K
EUR J PEDIATR. 1996;155(8):640-648.

[Induction of multiple melanocytic nevus cell nevi in 2 children with malignant hematologic systemic diseases and chemotherapy-induced immunosuppression]
Jappe U, Abeck D, Janka-Schaub G, Gross G, Jakob T, Ring J
HAUTARZT. 1996;47(7):537-540.

Fatal outcome of disseminated candidosis after allogeneic bone marrow transplantation under treatment with liposomal and conventional amphotericin-B. A report of 4 cases with determination of the Mic values.
Krüger W, Sobottka I, Stockschläder M, Mross K, Hoffknecht M, Rüssmann B, Horstmann M, Betker R, Zander A
SCAND J INFECT DIS. 1996;28(3):313-316.

Inherited defects of the protein C anticoagulant system in childhood thrombo-embolism
Nowak-Göttl U, Auberger K, Göbel U, Kreuz W, Schneppenheim R, Vielhaber H, Zenz W, Zieger B
EUR J PEDIATR. 1996;155(11):921-7.

Normal human serum contains a natural IgM antibody cytotoxic for human neuroblastoma cells.
Ollert M, David K, Schmitt C, Hauenschild A, Bredehorst R, Erttmann R, Vogel C
P NATL ACAD SCI USA. 1996;93(9):4498-4503.

Incidence and clinical outcome of children with BCR/ABL-positive acute lymphoblastic leukemia (ALL). A prospective RT-PCR study based on 673 patients enrolled in the German pediatric multicenter therapy trials ALL-BFM-90 and CoALL-05-92.
Schlieben S, Borkhardt A, Reinisch I, Ritterbach J, Janssen J, Ratei R, Schrappe M, Repp R, Zimmermann M, Kabisch H, Janka-Schaub G, Bartram C, Ludwig W, Riehm H, Lampert F, Harbott J
LEUKEMIA. 1996;10(6):957-963.

Defective dimerization of von Willebrand factor subunits due to a Cys-> Arg mutation in type IID von Willebrand disease
Schneppenheim R, Brassard J, Krey S, Budde U, Kunicki T, Holmberg L, Ware J, Ruggeri Z
P NATL ACAD SCI USA. 1996;93(8):3581-6.

Results of a screening for von Willebrand disease type 2N in patients with suspected haemophilia A or von Willebrand disease type 1
Schneppenheim R, Budde U, Krey S, Drewke E, Bergmann F, Lechler E, Oldenburg J, Schwaab R
THROMB HAEMOSTASIS. 1996;76(4):598-602.

Use of cryopreserved bone marrow in unrelated allogeneic transplantation.
Stockschläder M, Krüger W, Tom Dieck A, Horstmann M, Altnöder M, Löliger C, Fiedler W, Hoffknecht M, Erttmann R, Zander A
BONE MARROW TRANSPL. 1996;17(2):197-199.

Geographic distribution and origin of CFTR mutations in Germany
Tümmler B, Storrs T, Dziadek V, Dörk T, Meitinger T, Golla A, Bertele-Harms R, Harms H, Schröder E, Claass A, Rutjes J, Schneppenheim R, Bauer I, Breuel K, Stuhrmann M, Schmidtke J, Lindner M, Eigel A, Horst J, Kaiser R, Lentze M, Schmidt K, von der Hardt H, Estivill X
HUM GENET. 1996;97(6):727-31.

1995

Structurally modified anthracyclines retain activity in a cell line with simultaneous typical and atypical multidrug resistance.
Bielack S, Kallenbach K, Looft G, Erttmann R, Winkler K
ANTICANCER RES. 1995;15(4):1279-1284.

First case of disseminated Mycobacterium avium infection following chemotherapy for childhood acute myeloid leukemia
Claass A, Claviez A, Westphal E, Rüsch-Gerdes S, Schneppenheim R
INFECTION. 1995;23(5):301-2.

Cyclophosphamide/antithymocyte globulin conditioning of patients with severe aplastic anemia transplanted with bone marrow from HLA-identical related donors
Horstmann M, Stockschläder M, Kabisch H, Zander A
BLOOD. 1995;85(5):1404-5.

Cyclophosphamide/antithymocyte globulin conditioning of patients with severe aplastic anemia for marrow transplantation from HLA-matched siblings
Horstmann M, Stockschläder M, Krüger W, Hoffknecht M, Betker R, Kabisch H, Zander A
ANN HEMATOL. 1995;71(2):77-81.

Cyclophosphamide/antithymocyte globulin conditioning of patients with severe aplastic anemia for marrow transplantation from HLA-matched siblings: preliminary results.
Horstmann M, Stockschläder M, Krüger W, Hoffknecht M, Betker R, Kabisch H, Zander A
ANN HEMATOL. 1995;71(2):77-81.

Experience with liposomal Amphotericin-B in 60 patients undergoing high-dose therapy and bone marrow or peripheral blood stem cell transplantation.
Krüger W, Stockschläder M, Rüssmann B, Berger C, Hoffknecht M, Sobottka I, Kohlschütter B, Kroschke G, Kröger N, Horstmann M
BRIT J HAEMATOL. 1995;91(3):684-690.

Liver iron stores in patients with secondary haemosiderosis under iron chelation therapy with deferoxamine or deferiprone.
Nielsen P, Fischer R, Engelhardt R, Tondüry P, Gabbe E, Janka-Schaub G
BRIT J HAEMATOL. 1995;91(4):827-833.

Identification of a candidate missense mutation in a family with von Willebrand disease type IIC
Schneppenheim R, Thomas K, Krey S, Budde U, Jessat U, Sutor A, Zieger B
HUM GENET. 1995;95(6):681-6.

Von Willebrand disease in childhood
Schneppenheim R, Thomas K, Sutor A
SEMIN THROMB HEMOST. 1995;21(3):261-75.

Complete resection before development of drug resistance is essential for survival from advanced hepatoblastoma--a report from the German Cooperative Pediatric Liver Tumor Study HB-89.
von Schweinitz D, Hecker H, Harms D, Bode U, Weinel P, Bürger D, Erttmann R, Mildenberger H
J PEDIATR SURG. 1995;30(6):845-852.

[Intraspinal metastasis of stage I anaplastic Wilms tumor]
Wiegel T, Grzyska U, Schwarz R, Escherich G
STRAHLENTHER ONKOL. 1995;171(5):296-299.

1994

Malignant histiocytosis and large cell anaplastic (Ki-1) lymphoma in childhood: guidelines for differential diagnosis--report of the Histiocyte Society.
Bucsky P, Favara B, Feller A, Nezelof C, Radzun H, Schlegelberger B, Janka-Schaub G
Med Pediatr Oncol. 1994;22(3):200-203.

The impact of EBV, proliferation rate, and Bcl-2 expression in Hodgkin's disease in childhood
Claviez A, Tiemann M, Peters J, Kreipe H, Schneppenheim R, Parwaresch R
ANN HEMATOL. 1994;68(2):61-6.

Relapse of MALT lymphoma associated with Helicobacter pylori after antibiotic treatment.
Horstmann M, Erttmann R, Winkler K
LANCET. 1994;343(8905):1098-1099.

Screening for neuroblastoma.
Schilling F, Erttmann R, Ambros P, Strehl S, Christiansen H, Kovar H, Kabisch H, Treuner J
LANCET. 1994;344(8930):1157-1158.

Genetic heterogeneity of severe von Willebrand disease type III in the German population
Schneppenheim R, Krey S, Bergmann F, Bock D, Budde U, Lange M, Linde R, Mittler U, Meili E, Mertes G
HUM GENET. 1994;94(6):640-52.

[Results of the HB-89 Study in treatment of malignant epithelial liver tumors in childhood and concept of a new HB-94 protocol]
von Schweinitz D, Bürger D, Bode U, Weinel P, Erttmann R, Hecker H, Mildenberger H
KLIN PADIATR. 1994;206(4):282-288.

1993

Intraarterial chemotherapy for osteosarcoma: does the result really justify the effort?
Bielack S, Bieling P, Erttmann R, Winkler K
Cancer Treat Res. 1993;62:85-92.

Phenylalanine, other large neutral amino acids and RNA catabolites as markers for protein biosynthesis in phenylketonuria.
Clemens P, Burmester J, Wiegand G, Prankel B, Halfmann E, Erb N, Müller-Wickop J
METABOLISM. 1993;42(4):531-532.

Extracellular purine nucleosides elevated in chronic recidiving central nervous injury by deranged metabolism in phenylketonuria.
Clemens P, Prankel B, Halfman E, Erb N, Müller-Wickop J
MED HYPOTHESES. 1993;41(3):287-288.

[BEP/VIP in children and adolescents with malignant non-testicular germ cell tumors. A comparison of the results of treatment of therapy studies MAKEI 83/86 and 89P/89]
Göbel U, Calaminus G, Teske C, Bamberg M, Bökkerink J, Haas R, Holschneider A, Janka-Schaub G, Jürgens H, Mittler U
KLIN PADIATR. 1993;205(4):231-240.

von Willebrand factor mutation enhancing interaction with platelets in patients with normal multimeric structure
Holmberg L, Dent J, Schneppenheim R, Budde U, Ware J, Ruggeri Z
J CLIN INVEST. 1993;91(5):2169-77.

Reversal of multidrug resistance in Friend leukemia cells by dexniguldipine-HCl.
Reymann A, Looft G, Woermann C, Dietel M, Erttmann R
CANCER CHEMOTH PHARM. 1993;32(1):25-30.

1992

[Effect of dose intensity and therapy-induced leukocytopenia in intensive therapy on the prognosis of acute lymphatic leukemia in childhood. Results in 213 patients of the COALL-85 study]
Gobrecht O, Göbel U, Graubner U, Gutjahr P, Schöck V, Spaar H, Janka-Schaub G
KLIN PADIATR. 1992;204(4):230-235.

Infectious risks of Broviac catheters in children with neoplastic diseases: a matched pairs analysis.
Harms D, Görtitz I, Lambrecht W, Kabisch H, Erttmann R, Janka-Schaub G
PEDIATR INFECT DIS J. 1992;11(12):1014-1018.

Treatment of chronic neutropenia of childhood responsive to cyclosporin A in vitro and in vivo.
Janka-Schaub G, Raghavachar A, Rister M, Belohradsky B
INT J HEMATOL. 1992;55(2):157-163.

[Preoperative chemotherapy of nephroblastoma. Preliminary results of the SIOP-9/GPO therapy study]
Ludwig R, Weirich A, Pötter R, Harms D, Bürger D, Michaelis J, Erttmann R, Weinel P, Haas R, Ritter J
KLIN PADIATR. 1992;204(4):204-213.

[Early neuroblastoma detection in Germany. On the status of the Hamburg-Stuttgart cooperative pilot study]
Schilling F, Erttmann R, Dohrmann S, Erb N, Winkler K, Gross U, Treuner J
KLIN PADIATR. 1992;204(4):282-287.

1991

Neuroblastoma screening: arguments from retrospective analysis of three German neuroblastoma trials.
Berthold F, Hunneman D, Käser H, Harms D, Bertram U, Erttmann R, Schilling F, Treuner J, Zieschang J
J PEDIAT HEMATOL ONC. 1991;13(1):8-13.

Conserved cytostatic activity of aclarubicin in a doxorubicin selected Friend leukaemia cell line with multifactorial multidrug resistance.
Erttmann R, Münchmeyer M, Looft G, Winkler K
EUR J CANCER. 1991;27(8):1064.

Six-year experience with a comprehensive approach to the treatment of recurrent childhood acute lymphoblastic leukemia (ALL-REZ BFM 85). A relapse study of the BFM group.
Henze G, Fengler R, Hartmann R, Kornhuber B, Janka-Schaub G, Niethammer D, Riehm H
BLOOD. 1991;78(5):1166-1172.

[Familial hemophagocytic lymphohistiocytosis]
Hesse C, Hansmann M, Janka-Schaub G, Rontogianni D, Radzun H, Fischer R
Verh Dtsch Ges Pathol. 1991;75:200-204.

[Initial response to therapy as an important prognostic factor in acute lymphoblastic leukemia in childhood. COALL study group]
Janka-Schaub G, Stührk H, Kortüm B, Graubner U, Jürgens H, Spaar H, Schöck V, Dohrn B, Bahr R, Winkler K
KLIN PADIATR. 1991;203(4):231-235.

Discrepant results of different tests for antibodies to hepatitis C in children with malignant diseases and in patients on renal replacement therapy
Rautenberg P, Schneppenheim R, Leimenstoll G, Behnke H, Loose G
EUR J CLIN MICROBIOL. 1991;10(11):978-81.

Luminography--a new, highly sensitive visualization method for electrophoresis
Schneppenheim R, Budde U, Dahlmann N, Rautenberg P
ELECTROPHORESIS. 1991;12(5):367-72.

Seroprevalence and significance of antibodies to hepatitis C virus in pediatric patients with malignant diseases
Schneppenheim R, Rautenberg P, Behnke H, Vietor K
KLIN PADIATR. 1991;203(4):273-5.

1990

Luminographic detection of von Willebrand factor multimers in agarose gels and on nitrocellulose membranes
Budde U, Schneppenheim R, Plendl H, Dent J, Ruggeri Z, Zimmerman T
THROMB HAEMOSTASIS. 1990;63(2):312-5.

Risk of CNS relapse after systemic relapse of childhood acute lymphoblastic leukemia.
Fengler R, Hartmann R, Bode U, Janka-Schaub G, Jürgens H, Riehm H, Henze G
Haematol Blood Transfus. 1990;33:511-515.

Cytogenetics of childhood acute lymphoblastic leukemia in multicenter trials.
Harbott J, Ritterbach J, Janka-Schaub G, Ludwig W, Reiter A, Riehm H, Lampert F
Haematol Blood Transfus. 1990;33:451-458.

[Therapy of sickle cell crisis]
Janka-Schaub G
DEUT MED WOCHENSCHR. 1990;115(42):1611.

Improved prognosis for childhood acute lymphocytic leukemia with very high white blood cell count (greater than 100/nl) with rotation of non-cross-resistant drug combinations.
Janka-Schaub G, Goebel U, Graubner U, Haas R, Juergens H, Spaar H, Winkler K
Haematol Blood Transfus. 1990;33:489-493.

Effect of intraarterial versus intravenous cisplatin in addition to systemic doxorubicin, high-dose methotrexate, and ifosfamide on histologic tumor response in osteosarcoma (study COSS-86).
Winkler K, Bielack S, Delling G, Salzer-Kuntschik M, Kotz R, Greenshaw C, Jürgens H, Ritter J, Kusnierz-Glaz C, Erttmann R
CANCER-AM CANCER SOC. 1990;66(8):1703-1710.

1989

Platinum disposition after intraarterial and intravenous infusion of cisplatin for osteosarcoma. Cooperative Osteosarcoma Study Group COSS.
Bielack S, Erttmann R, Looft G, Purfürst C, Delling G, Winkler K, Landbeck G
CANCER CHEMOTH PHARM. 1989;24(6):376-380.

Doxorubicin: effect of different schedules on toxicity and anti-tumor efficacy.
Bielack S, Erttmann R, Winkler K, Landbeck G
Eur J Cancer Clin Oncol. 1989;25(5):873-882.

Natural killer cell function and interferon production in familial hemophagocytic lymphohistiocytosis.
Eife R, Janka-Schaub G, Belohradsky B, Holtmann H
PEDIATR HEMAT ONCOL. 1989;6(3):265-272.

[Anthracycline transport in sensitive and resistant leukemia cells]
Erttmann R, Erb N, Forcadell de Dios P, Neurath C, Looft G, Landbeck G
KLIN PADIATR. 1989;201(1):40-45.

An EcoRI polymorphism in the human von Willebrand factor (vWF) gene
Ewerhardt B, Ludwig M, Schwaab R, Schneppenheim R, Olek K
NUCLEIC ACIDS RES. 1989;17(13):5416.

[Intracranial germ cell tumors: analysis of the therapy study MAKEI 83/86 and changes in protocol for the follow-up study]
Göbel U, Bamberg M, Budach V, Haas R, Janka-Schaub G, Kühl J, Lenard H, Rister M, Spaar H
KLIN PADIATR. 1989;201(4):261-268.

[Non-testicular germ cell tumors: analysis of the therapy study MAKEI 83/86 anc changes in the protocol for the follow-up study]
Göbel U, Bamberg M, Haas R, Bökkerink J, Brämswig G, Calaminus G, Engert J, Gadner H, Havers W, Janka-Schaub G
KLIN PADIATR. 1989;201(4):247-260.

Familial hemophagocytic lymphohistiocytosis macrophages showing immunohistochemical properties of activated macrophages and T-accessory cells.
Hansmann M, Rontogianni D, Janka-Schaub G, Wacker H, Hinkeldey K, Radzun H
PEDIATR HEMAT ONCOL. 1989;6(3):237-246.

Familial hemophagocytic lymphohistiocytosis: diagnostic problems and differential diagnosis.
Janka-Schaub G
PEDIATR HEMAT ONCOL. 1989;6(3):219-225.

Familial hemophagocytic lymphohistiocytosis: therapy in the German experience.
Janka-Schaub G
PEDIATR HEMAT ONCOL. 1989;6(3):227-231.

1988

[Myeloablative chemo- and radiotherapy with autologous and allogenic bone marrow reconstitution in children with metastatic neuroblastoma]
Berthold F, Bender-Götze C, Dopfer R, Erttmann R, Haas R, Henze G, Körbling M, Riehm H, Rister M, Stollmann B
KLIN PADIATR. 1988;200(3):221-225.

[Antineoplastic effectiveness and toxicity of idarubicin (4-demethoxy-daunorubicin) in recurrent acute leukemias in childhood]
Erttmann R, Bode U, Erb N, Forcadell de Dios P, Gutjahr P, Haas R, Kuhn N, Siewert H, Landbeck G
KLIN PADIATR. 1988;200(3):200-204.

Pharmacokinetics of doxorubicin in man: dose and schedule dependence.
Erttmann R, Erb N, Steinhoff A, Landbeck G
J CANCER RES CLIN. 1988;114(5):509-513.

Long term doxorubicin cardiotoxicity in childhood: non-invasive evaluation of the contractile state and diastolic filling.
Hausdorf G, Morf G, Beron G, Erttmann R, Winkler K, Landbeck G, Keck E
Br Heart J. 1988;60(4):309-315.

Rapidly rotating combination chemotherapy in childhood acute lymphoblastic leukemia: preliminary results of a randomized comparison with conventional treatment.
Janka-Schaub G, Winkler K, Göbel U, Graubner U, Gutjahr P, Haas R, Jürgens H, Spaar J
LEUKEMIA. 1988;2(12):.

[The COALL-85 cooperative study for risk patients with acute lymphatic leukemia: initial results]
Janka-Schaub G, Winkler K, Göbel U, Graubner U, Schwenger M, Haas R, Jürgens H, Spaar J
KLIN PADIATR. 1988;200(3):171-176.

Luminography--an alternative assay for detection of von Willebrand factor multimers
Schneppenheim R, Plendl H, Budde U
THROMB HAEMOSTASIS. 1988;60(2):133-6.

Aplastic crisis caused by parvovirus B19 infection.
Schwarz T, Roggendorf M, Janka-Schaub G
EUR J CLIN MICROBIOL. 1988;7(1):87-88.

1987

[Langerhans cell histiocytosis in childhood--results of the DAL-HX 83 study]
Gadner H, Heitger A, Ritter J, Göbel U, Janka-Schaub G, Kühl J, Bode U, Spaar H
KLIN PADIATR. 1987;199(3):173-182.

Early intensification therapy in high-risk childhood acute lymphocytic leukemia: lack of benefit from high-dose methotrexate.
Janka-Schaub G, Winkler K, Juergens H, Goebel U
Haematol Blood Transfus. 1987;30:456-460.

[Detection of neuroblastoma cells in bone marrow by Southern blot and in situ hybridization using a NMYC DNA probe]
Kabisch H, Heinsohn S, Milde K, Löning T, Bartl S, Erttmann R, Landbeck G
MONATSSCHR KINDERH. 1987;135(4):210-213.

Nachweis von Neuroblastomzellen im Knochenmark durch "Southern-Blot" und "In situ-Hybridisierung" mit Hilfe einer NMYC-DNS-Probe
Kabisch H, Heinsohn S, Milde-Langosch K, Löning T, Bartl S, Erttmann R, Landbeck G
MONATSSCHR KINDERH. 1987;135(4):210-3.

A luminescence Western blot with enhanced sensitivity for antibodies to human immunodeficiency virus
Schneppenheim R, Rautenberg P
EUR J CLIN MICROBIOL. 1987;6(1):49-51.

1986

A rapid chromatographic procedure for the determination of adriamycin, daunomycin and their 13-OH metabolites adriamycinol and daunomycinol.
Erb N, Erttmann R, Landbeck G
CANCER CHEMOTH PHARM. 1986;17(1):53-55.

Determination of 7-hydroxymethotrexate in human plasma by reversed phase high-performance liquid chromatography.
Erttmann R, Bielack S, Landbeck G
ONCOLOGY. 1986;43(2):86-88.

[The pharmacokinetics of doxorubicin]
Erttmann R, Grandt M, Erb N, Garbrecht M, Landbeck G
KLIN PADIATR. 1986;198(3):271-276.

Intermediate-dose methotrexate in the treatment of childhood acute lymphocytic leukaemia: lack of benefit during maintenance therapy following intensive induction therapy.
Janka-Schaub G, Winkler K, Jürgens H, Goebel U, Gutjahr P, Spaar H
EUR J PEDIATR. 1986;145(1-2):14-17.

Detection of neuroblastoma cells in bone marrow by in situ hybridization.
Kabisch H, Heinsohn S, Milde K, Löning T, Bartl S, Erttmann R
EUR J PEDIATR. 1986;145(4):323-324.

Meta-iodobenzylguanidine scintigraphy in neuroblastoma--a comparison with conventional X-ray and ultrasound.
Müller-Gärtner H, Erttmann R, Helmke K
PEDIATR HEMAT ONCOL. 1986;3(2):97-109.

The age dependency of the creatinine-related concentration of ribonucleosides in human urine.
Müller-Wickop J, Lorenz H, Winkler K, Erb N
J Clin Chem Clin Biochem. 1986;24(12):993-999.

[Effect of a local surgical procedure on the incidence of metastases following neoadjuvant chemotherapy of osteosarcoma]
Winkler K, Beron G, Kotz R, Salzer-Kuntschik M, Beck J, Beck W, Brandeis W, Ebell W, Erttmann R, Göbel U
Z ORTHOP GRENZGEB. 1986;124(1):22-29.

1985

7-Hydroxy-methotrexate and clinical toxicity following high-dose methotrexate therapy.
Erttmann R, Bielack S, Landbeck G
J CANCER RES CLIN. 1985;109(1):86-88.

Kinetics of 7-hydroxy-methotrexate after high-dose methotrexate therapy.
Erttmann R, Bielack S, Landbeck G
CANCER CHEMOTH PHARM. 1985;15(2):101-104.

[Clinical significance of non-renal elimination mechanisms of methotrexate (MTX)]
Erttmann R, Gkanatsas A
MONATSSCHR KINDERH. 1985;133(8):516-519.

Effect of oral cholestyramine on the elimination of high-dose methotrexate.
Erttmann R, Landbeck G
J CANCER RES CLIN. 1985;110(1):48-50.

[The Munich study on the treatment of acute lymphoblastic leukemia in childhood (ALL 77-02)]
Graubner U, Haas R, Janka G, Janka-Schaub G, Kohne E, Rieber E
KLIN PADIATR. 1985;197(3):207-214.

[Scintigraphy with radioiodinated meta-iodobenzylguanidine in the diagnosis of neuroblastoma]
Müller-Gärtner H, Erttmann R, Helmke K
NUKLEARMED-NUCL MED. 1985;24(5-6):222-226.

An improved method for the simultaneous analysis of normal and modified urinary nucleosides and nucleobases by high performance liquid chromatography.
Sander G, Wieland J, Topp H, Heller-Schöch G, Erb N, Schöch G
CLIN CHIM ACTA. 1985;152(3):355-361.

1984

In vivo production of childhood acute lymphoblastic leukemia cells in relation to ploidy and immunological subtype.
Dörmer P, Janka-Schaub G, Lau B, Haas R, Janka G
LEUKEMIA RES. 1984;8(4):587-595.

Prolonged methotrexate infusions in children with acute leukemia in relapse and in remission and with medulloblastoma. Pharmacokinetics, toxicity and clinical results.
Janka-Schaub G, Mack R, Helmig M, Haas R, Bidlingmaier F
ONCOLOGY. 1984;41(4):225-232.

Neoadjuvant chemotherapy for osteogenic sarcoma: results of a Cooperative German/Austrian study.
Winkler K, Beron G, Kotz R, Salzer-Kuntschik M, Beck J, Beck W, Brandeis W, Ebell W, Erttmann R, Göbel U
J CLIN ONCOL. 1984;2(6):617-624.

1983

Determination of aclacinomycin A by reversed-phase high-performance liquid chromatography.
Erttmann R
J CHROMATOGR A. 1983;277:433-435.

Pancreatic sonography in thalassemia major.
Erttmann R, Hausdorf G, Landbeck G
KLIN PADIATR. 1983;195(2):97-99.

[Intracranial metastasis in neuroblastoma]
Erttmann R, Heller M, Veelken N, Landbeck G
Z Kinderchir. 1983;38(5):333-335.

[Wiskott-Aldrich syndrome]
Erttmann R, Thöne I, Landbeck G
MONATSSCHR KINDERH. 1983;131(8):524-527.

[Treatment strategy in non-testicular malignant germ cell tumors in children and adolescents--concept of the MAKEI 83 cooperative therapeutic study of the Society for Pediatric Oncology]
Göbel U, Haas R, Harms D, Janka-Schaub G, Brämswig J, Jürgens H, Weissbach L, Faber P, Müller E
KLIN PADIATR. 1983;195(3):201-206.

[Malignant testicular tumors in children and adolescents: concept of the MAHO 82 cooperative therapeutic study of the Society for Pediatric Oncology]
Haas R, Brämswig J, Göbel U, Harms D, Janka-Schaub G, Weissbach L
KLIN PADIATR. 1983;195(3):196-200.

Therapy of acute lymphocytic leukemia in childhood with intermediate dose methotrexate and CNS irradiation. A report of the ALL 77-02 study group.
Haas R, Janka G, Janka-Schaub G, Kohne E, Netzel B
Blut. 1983;47(6):321-331.

[Invasive aspergillosis with an intrapulmonary fungus ball in childhood]
Hausdorf G, Erttmann R
KLIN PADIATR. 1983;195(2):129-132.

Familial hemophagocytic lymphohistiocytosis.
Janka-Schaub G
EUR J PEDIATR. 1983;140(3):221-230.

Multivariate analysis of urinary RNA catabolites in malignancies: cross-sectional and longitudinal studies.
Müller J, Erb N, Heller-Schöch G, Lorenz H, Winkler K, Schöch G
Recent Results Cancer Res. 1983;84:317-330.

Serological inhibition of graft versus host disease: recent results in 28 patients with leukemia.
Rodt H, Thierfelder S, Bender-Götze C, Dopfer R, Haas F, Janka-Schaub G, Kolb H, Link H, Netzel B, Niethammer D, Schüch K, Wilms K
Haematol Blood Transfus. 1983;28:92-96.

[COALL-80 therapy in the management of acute lymphoblastic leukemia in childhood--an interim report]
Winkler K, Beron G, Erttmann R, Jürgens H, Göbel U, Gutjahr P, Kabisch H, Kuhn N, Spaar H, Drescher J, Thomas P, Landbeck G
KLIN PADIATR. 1983;195(3):161-167.

Adjuvant chemotherapy in osteosarcoma - effects of cisplatinum, BCD, and fibroblast interferon in sequential combination with HD-MTX and adriamycin. Preliminary results of the COSS 80 study.
Winkler K, Beron G, Kotz R, Salzer-Kuntschik M, Beck J, Beck W, Brandeis W, Ebell W, Erttmann R, Göbel U, Havers W, Henze G, Hinderfield L, Höcker P, Jobke A, Jürgens H, Kabisch H, Landbeck G, Preusser P, Prindull G, Ramach W, Ritter J, Sekera J, Treuner J, Wüst G
J CANCER RES CLIN. 1983;106:1-7.

1982

[Excretion of methylated nucleosides in the initial therapy phase in a case of anorexia nervosa]
Clemens P, Schöch G, Ziemer G, Altenhoff J, Erb N, Lorenz H, Müller J, Grüttner R
Padiatr Padol. 1982;17(2):157-163.

[Improved prognosis in Wilms' tumor due to adjuvant combination drug therapy]
Haas R, Helmig F, Hausner H, Eife R, Devens K, Janka-Schaub G, Helmig M, Lampert F
ONKOLOGIE. 1982;5(2):60-66.

[So-called histiocytosis X and malignant histiocytosis]
Haas R, Janka-Schaub G, Helmig M, Meister P
ONKOLOGIE. 1982;5(1):4-12.

[Sonographic findings in malignant lymphoblastic T-cell lymphomas in childhood]
Hausdorf G, Erttmann R, Hübner C, Winkler K
ONKOLOGIE. 1982;5(6):284-288.

1981

[Medulloblastoma cerebelli in childhood--retrospective evaluation of diagnostic methods and therapy (author's transl)]
Berthold R, Janka-Schaub G, Lampert F
KLIN PADIATR. 1981;193(3):189-197.

[The cyanogenic glycosides of triticum, secale and sorghum.]
Erb N, Zinsmeister H, Nahrstedt A
PLANTA MED. 1981;41(1):84-89.

[Infections in children with leukaemia or malignant tumour treated with cytostatic agents: long-term study of 200 cases (author's transl)]
Goetz O, Peller P, Haas R, Janka-Schaub G
DEUT MED WOCHENSCHR. 1981;106(14):421-423.

[All 77-01 therapy study for treatment of acute lymphocytic leukemia in childhood (author's transl)]
Haas R, Janka-Schaub G, Netzel B, Helmig M
KLIN PADIATR. 1981;193(3):137-144.

Familial lymphohistiocytosis.
Janka-Schaub G, Belohradsky B, Däumling S, Müller-Höcker J, Meister P, Haas R
Haematol Blood Transfus. 1981;27:245-253.

Intravenous and subcutaneous desferrioxamine therapy in children with severe iron overload.
Janka-Schaub G, Möhring P, Helmig M, Haas R, Betke K
EUR J PEDIATR. 1981;137(3):285-290.

Microrheological aspects in extreme leukocytotic acute childhood leukemia.
Klose H, Kelson S, Janka-Schaub G, Schwarzbach K, Haas R, Betke K
Bibl Haematol. 1981;47:258-263.

[Initial treatment of acute childhood leukemia with extreme leukocytosis by blood exchange transfusion -- rheological aspects (author's transl)]
Klose H, Kelson S, Schwarzbach K, Janka-Schaub G, Netzel B, Haas R, Betke K
KLIN PADIATR. 1981;193(3):172-176.

[Bone marrow transplantation for aplastic anaemia (author's transl)]
Kolb H, Wündisch G, Spitzer I, Ochsler H, Stengel-Rutkowski L, Bender-Götze C, Albert E, Sauer H, Ledderose G, Brehm G, Jehn U, Eckstein R, Mempel W, Wilmanns W, Haas R, Helmig M, Netzel B, Belohradsky B, Janka-Schaub G, Rodt H, GrosseWWilde H, Thiel E, von Lieven H, Roloff R, Krimmel B, Bunde E, Wank R, Schendel D
Klin Wochenschr. 1981;59(7):325-342.

[Bone marrow transplantation in acute leukemias: antibody treatment for suppression of graft-versus-host disease (author's transl)]
Rodt H, Netzel B, Kolb H, Haas R, Wilms K, Bender-Götze C, Wernet P, Janka-Schaub G, Link H, Wilmanns W, Thierfelder S
Blut. 1981;43(2):113-118.

[Presentation of the cooperative study COALL-80 on treatment of childhood ALL (author's transl)]
Winkler K, Matzke E, Caspers S, Erttmann R, Grosch-Wörner I, Kabisch H, Müller J, Landbeck G
KLIN PADIATR. 1981;193(3):155-158.

1980

Effects of probenecid on plasma/tissue distribution of 14C-benzylpenicillin in rats.
Bergholz H, Erttmann R, Damm K
Experientia. 1980;36(3):333-334.

[Acute juvenile lymphoblastic leukemia]
Haas R, Janka-Schaub G, Helmig M, Netzel B
MMW Munch Med Wochenschr. 1980;122(9):301-304.

Antibody incubation of human marrow graft for prevention graft versus host disease.
Haas R, Janka-Schaub G, Netzel B, Rodt H, Thierfelder S, Helmig M, Eife R, Belohradsky B, Kolb H, Betke K
Blut. 1980;40(6):387-397.

The concept of antileukemic, autologous bone marrow transplantation in acute lymphoblastic leukemia.
Netzel B, Rodt H, Haas R, Janka-Schaub G, Thierfelder S
Haematol Blood Transfus. 1980;25:297-307.

Wolman's disease: clinical, biochemical and ultrastructural studies in an unusual case without striking adrenal calcification.
Schaub J, Janka G, Christomanou H, Sandhoff K, Permanetter W, Janka-Schaub G, Meister P
EUR J PEDIATR. 1980;135(1):45-53.

Total aganglionosis of the colon and Ondine's curse.
Stern M, Erttmann R, Hellwege H, Kuhn N
LANCET. 1980;1(8173):877-878.

[Radiation therapy of the renal tumor in children (author's transl)]
von Lieven H, Kurz S, Haas R, Janka-Schaub G, Devens K
Strahlentherapie. 1980;156(6):388-393.

1979

[Non-Hodgkin's lymphoma in children: improved prognosis through aggressive multiple drug combination and irradiation (author's transl)]
Janka-Schaub G, Lau B, Meister P, Lampert F, Haas R
KLIN PADIATR. 1979;191(1):40-46.

[High-dose methotrexate therapy in osteogenic sarcoma: plasma pharmakokinetics to predict toxicity (author's transl)]
Janka-Schaub G, Wiesner H, Bidlingmaier F, Haas R
Klin Wochenschr. 1979;57(8):411-416.

[Hydrocyanic acid content in cerals and cereal products]
Lehmann G, Zinsmeister H, Erb N, Neunhoeffer O
Z Ernahrungswiss. 1979;18(1):16-22.

Osteosarcoma: histological evaluation and grading.
Meister P, Konrad E, Lob G, Janka-Schaub G, Keyl W, Stürz H
ARCH ORTHOP TRAUM SU. 1979;94(2):91-98.

GVHD suppression by incubation of bone marrow grafts with anti-T-cell globulin: effect in the canine model and application to clinical bone marrow transplantation.
Rodt H, Kolb H, Netzel B, Rieder I, Janka-Schaub G, Belohradsky B, Haas R, Thierfelder S
TRANSPL P. 1979;11(1):962-966.

1978

[Juvenile rhabdomyosarcoma. Diagnosis and new therapeutic possibilities]
Haas R, Devens K, Helmig M, Janka-Schaub G, Klose H, Lampert F
ONKOLOGIE. 1978;1(4):142-148.

[Diagnostik significance of cell membrane markers in childhood ALL (author's transl)]
Haas R, Netzel B, Janka-Schaub G, Rodt H, Thiel E, Thierfelder S
KLIN PADIATR. 1978;190(5):446-452.

[Malignant juvenile bone tumors]
Janka-Schaub G
MED KLIN-INTENSIVMED. 1978;73(22):815-818.

Combination chemotherapy and radiotherapy for Hodgkin's disease in children.
Janka-Schaub G, Lau B, Haas R, von Lieven H, Lampert F
EUR J PEDIATR. 1978;127(4):287-292.

Lymphoblast cell size and prognosis in acute lymphoblastic leukemia in childhood.
Janka-Schaub G, Teige-Singer S, Haas R, Lau B
Blut. 1978;37(2):89-94.

[Abt-Letterer-Siwe disease. Diagnosis and therapy (author's transl)]
Wolff H, Janka-Schaub G
MONATSSCHR KINDERH. 1978;126(7):425-430.

1977

In vitro functions of lymphoid cells in untreated childhood acute lymphoblastic leukemia.
Eife R, Kopecky M, Lau B, Janka-Schaub G, Haas R, Lampert F
Haematol Blood Transfus. 1977;20:209-213.

[Neuroblastoma: paraneoplastic diseases and late complications (author's transl)]
Holschneider A, Geiger H, Bolkenius N, Janka-Schaub G, Lampert F
MONATSSCHR KINDERH. 1977;125(2):69-73.

Childhood malignant lymphoma. Favourable outlook with aggressive combination chemotherapy and radiotherapy.
Lau B, Janka-Schaub G, Meister P, Lampert F, Haas R
EUR J CANCER. 1977;13(11):1237-1240.

1975

[Distrubances in glucose metabolism during diphenyhydantoin treatment in childhood]
Janka G, Toyka K, Janka-Schaub G, Förster C
Bibl Psychiatr. 1975;151:172-175.

Letzte Aktualisierung aus dem FIS: 20.08.2017 - 00:01 Uhr