Aktuelles

Symposium in honour of Michael Frotscher

*03.07.1947 Dresden †27.05.2017 Hamburg

EC-Tracing
EC-Tracing

Neurons, Synapses and Circuits Involved in the Processing of Information from the Entorhinal Cortex

The discovery of grid cells in the entorhinal cortex and place cells in the hippocampus, for which the Nobel Prize was awarded in 2014, was a major advance in our understanding of how information from the environment is conveyed to the hippocampus by characteristic activitypatterns. These activity patterns involve distinct neuronal types, neuronal circuits, and synapses, which are

undergoing intensive study in the hope of unveiling the specifics of the entorhino-hippocampal network. Despite the pioneering work of May-Britt and Edvard Moser on the grid cells, and of John O’Keefe on the place cells in the hippocampus proper, it still needs to be understood how the representation of space and the activity of grid cells in the entorhinal cortex, representing a “map” of the surrounding environment, is transferred to hippocampal place cells, which fire if the animal is in a specific position in space. This information transfer is likely to involve distinct neurons and their synaptic connections forming specific circuits, which are as yet poorly understood.

The symposium will bring together leading researchers from the field of entorhinal and/or hippocampal neurons and synapses and their functional circuits. We wish to stimulate fruitful discussions, aiming at summarizing the most up-to-date knowledge of leading scientists in the field, and at the same time developing novel concepts and even plans for future experiments.

Gaby Rune, Hamburg

Thomas Deller, Frankfurt

Robert Nitsch, Münster

Aktuelle Publikationen

2017

Sex-dependent regulation of aromatase-mediated synaptic plasticity in the basolateral amygdala.
Bender, R.A., Zhou, L., Vierk, R., Brandt, N., Keller, A., Gee, C.E., Schäfer, M.K., Rune G.M.
J Neurosci. 2016 Dec 27 doi: 10.1523/JNEUROSCI.1532-16.2016 (Epub ahead of print).

Neurodegeneration and NLRP3 inflammasome expression in the anterior thalamus of SOD1(G93A) ALS mice.
Debye., B., Schmülling, L., Zhou, L., Rune, G., Beyer, C., Johann, S.
Brian Pathol 2016 Nov 23. doi: 10.1111/bpa.12467 (Epub ahead of print).

From Shortage to Surge: A development Switsch in Hippocampal Prefrontal Coupling in a Gene-Environment Model of Neuropsychiatric Disorders.
Hartung, J., Cichon, N., De Feo, V., Riemann, S., Schildt, S., Lindemann, C., Mulert, C., Gogos, J.A., Hanganu-Opatz, I.L.
Cereb Cortex 2016 Sep 9 doi: 10.1093/cercor/bhw274 (Epub ahead of print)
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Synaptopodin is regulated by aromatase activity.
Fester, L., Zhou, L., Ossig, C., Labitzke, J., Bläute, C., Bader, M., Vollmer, G., Jarry, H., Rune, G.M.
J Neurochem 2016 Nov. 8 doi:10.1111/jnc.13889 (Epub ahead of print).

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2017

Experience-Dependent Regulation of Cajal-Retzius Cell Networks in the Developing and Adult Mouse Hippocampus
Anstötz M, Lee S, Neblett T, Rune G, Maccaferri G
CEREB CORTEX. 2017 [Epub ahead of print];1-16.

Sex-dependent regulation of aromatase-mediated synaptic plasticity in the basolateral amygdala
Bender R, Zhou L, Vierk R, Brandt N, Keller A, Gee C, Schäfer M, Rune G
J NEUROSCI. 2017;37(6):1532-1545.

Rate and Temporal Coding Convey Multisensory Information in Primary Sensory Cortices
Bieler M, Cichon N, Schildt S, Röder B, Hanganu-Opatz I
eNeuro. 2017;4(2):.

Visual-tactile processing in primary somatosensory cortex emerges before cross-modal experience
Bieler M, Sieben K, Schildt S, Röder B, Hanganu-Opatz I
SYNAPSE. 2017;71:6.

Layer-specific optogenetic activation of pyramidal neurons causes beta-gamma entrainment of neonatal networks
Bitzenhofer S, Ahlbeck J, Wolff A, Wiegert J, Gee C, Oertner T, Hanganu-Opatz I
NAT COMMUN. 2017;8:14563.

Synaptopodin is regulated by aromatase activity
Fester L, Zhou L, Ossig C, Labitzke J, Bläute C, Bader M, Vollmer G, Jarry H, Rune G
J NEUROCHEM. 2017;140(1):126-139.

Presynaptic localization of GluK5 in rod photoreceptors suggests a novel function of high affinity glutamate receptors in the mammalian retina
Haumann I, Junghans D, Anstötz M, Frotscher M
PLOS ONE. 2017;12(2):e0172967.

Neocortical Layer 6B as a Remnant of the Subplate - A Morphological Comparison
Marx M, Qi G, Hanganu-Opatz I, Kilb W, Luhmann H, Feldmeyer D
CEREB CORTEX. 2017;27(2):1011-1026.

Early-life stress impairs recognition memory and perturbs the functional maturation of prefrontal-hippocampal-perirhinal networks
Reincke S, Hanganu-Opatz I
SCI REP-UK. 2017;7:42042.

Glutamatergic deficit and schizophrenia-like negative symptoms
Thiebes S, Leicht G, Curic S, Steinmann S, Polomac N, Andreou C, Eichler I, Eichler L, Zöllner C, Gallinat J, Hanganu-Opatz I, Mulert C
J PSYCHIATR NEUROSCI. 2017;42(4):273-283.

2016

Developmental Profile, Morphology, and Synaptic Connectivity of Cajal-Retzius Cells in the Postnatal Mouse Hippocampus
Anstötz M, Huang H, Marchionni I, Haumann I, Maccaferri G, Lübke J
CEREB CORTEX. 2016;26(2):855-872.

Post mortem CT scans as a supplementary teaching method in gross anatomy
Buenting M, Mueller T, Raupach T, Luers G, Wehrenberg U, Gehl A, Anders S
ANN ANAT. 2016;208:165-169.

Neurodegeneration and NLRP3 inflammasome expression in the anterior thalamus of SOD1(G93A) ALS mice
Debye B, Schmülling L, Zhou L, Rune G, Beyer C, Johann S
BRAIN PATHOL. 2016 [Epub ahead of print].

Control of aromatase in hippocampal neurons
Fester L, Brandt N, Windhorst S, Pröls F, Bläute C, Rune G
J STEROID BIOCHEM. 2016;160:9-14.

Interdependent Conductances Drive Infraslow Intrinsic Rhythmogenesis in a Subset of Accessory Olfactory Bulb Projection Neurons
Gorin M, Tsitoura C, Kahan A, Watznauer K, Drose D, Arts M, Mathar R, O'Connor S, Hanganu-Opatz I, Ben-Shaul Y, Spehr M
J NEUROSCI. 2016;36(11):3127-44.

Thalamic and Entorhinal Network Activity Differently Modulates the Functional Development of Prefrontal-Hippocampal Interactions
Hartung H, Brockmann M, Pöschel B, De Feo V, Hanganu-Opatz I
J NEUROSCI. 2016;36(13):3676-90.

From Shortage to Surge: A Developmental Switch in Hippocampal-Prefrontal Coupling in a Gene-Environment Model of Neuropsychiatric Disorders
Hartung H, Cichon N, De Feo V, Riemann S, Schildt S, Lindemann C, Mulert C, Gogos J, Hanganu-Opatz I
CEREB CORTEX. 2016;26(11):4265-4281.

Accuracy of Latarjet graft and screw position after using novel drill guide.
Klatte T, Hartel M, Weiser L, Hoffmann M, Wehrenberg U, Heinemann A, Rueger J, Briem D
EUR J TRAUMA EMERG S. 2016 [Epub ahead of print].

Inositol-1,4,5-trisphosphate-3-kinase-A controls morphology of hippocampal dendritic spines
Köster J, Leggewie B, Blechner C, Brandt N, Fester L, Rune G, Schweizer M, Kindler S, Windhorst S
CELL SIGNAL. 2016;28(1):83-90.

Spindle Activity Orchestrates Plasticity during Development and Sleep
Lindemann C, Ahlbeck J, Bitzenhofer S, Hanganu-Opatz I
NEURAL PLAST. 2016;5787423.

Balancing family with a successful career in neuroscience
Poirazi P, Belin D, Gräff J, Hanganu-Opatz I, López-Bendito G
EUR J NEUROSCI. 2016;44(2):1797-803.

Aromatase Expression in the Hippocampus of AD Patients and 5xFAD Mice
Prange-Kiel J, Dudzinski D, Pröls F, Glatzel M, Matschke J, Rune G
NEURAL PLAST. 2016;9802086.

Oestradiol synthesized by female neurons generates sex differences in neuritogenesis
Ruiz-Palmero I, Ortiz-Rodriguez A, Melcangi R, Caruso D, Garcia-Segura L, Rune G, Arevalo M
SCI REP-UK. 2016;6:31891.

Phenylketonuria: Direct and indirect effects of phenylalanine
Schlegel G, Scholz R, Ullrich K, Santer R, Rune G
EXP NEUROL. 2016;281:28-36.

Autoantibodies against thrombospondin type 1 domain-containing 7A induce membranous nephropathy
Tomas N, Hoxha E, Reinicke A, Fester L, Helmchen U, Gerth J, Bachmann F, Budde K, Nolte F, Zahner G, Rune G, Lambeau G, Meyer-Schwesinger C, Stahl R
J CLIN INVEST. 2016;126(7):2519-32.

The road to independence. How to get funding in neuroscience
Yaksi E, Poirazi P, Hanganu-Opatz I
EUR J NEUROSCI. 2016;43(5):603-7.

Letzte Aktualisierung aus dem FIS: 22.09.2017 - 00:01 Uhr