AG Saugel


Name: Prof. Dr. med. Bernd Saugel
Clinic/Institute: Department of Anesthesiology, Center of Anesthesiology & Intensive Care Medicine
Email: b.saugel@uke.de
Phone: +49 (0) 40 7410 - 18866

Research Focus and Main research questions

Our research focus is the hemodynamic management of patients having major surgery and of critically ill patients. The superordinated goal of our research is to improve patient-centered outcomes in perioperative and intensive care medicine. We specifically focus on concepts of "personalized hemodynamic management" (Saugel B, et al. Curr Opin Crit Care. 2017. 23:334-341) using advanced innovative hemodynamic monitoring methods. We develop and investigate strategies to optimize blood pressure, blood flow, oxygen delivery, and microcirculatory perfusion in surgical patients before, during, and after surgery and in critically ill patients treated in the intensive care unit.

  • Methods
  • Methods

    Methods:

    • Clinical (multicenter) randomized-controlled trials in perioperative and intensive care medicine
    • Innovative hemodynamic monitoring methods to measure blood pressure, blood flow, oxygen delivery, and microcirculatory perfusion

  • Recent Funding:

    • Effect of personalized hemodynamic management targeting baseline cardiac index on postoperative complications and mortality in high-risk patients having major abdominal surgery: an international multicenter randomized controlled interventional clinical trial
    Baxter Healthcare Corporation (Deerfield, IL, USA)

    • Postopertive hypotension in patients after non-cardiac surgery: a prospective observational pilot study (POSEIDON study)
    Werner Otto Stiftung (Hamburg, Germany)

    • Effect of personalized perioperative blood pressure management on postoperative complications and mortality in high-risk patients having major abdominal surgery: protocol for a multicenter randomized trial (IMPROVE-multi)
    Deutsche Forschungsgemeinschaft (DFG) (Bonn, Germany)

    • The effect of intraoperative cardiac output-guided goal-directed hemodynamic therapy on perioperative oxygen delivery and consumption as well as microcirculatory perfusion in comparison to routine hemodynamic management.
    Werner Otto Stiftung (Hamburg, Germany)

    • Impact of perioperative personalized blood pressure management on postoperative complications and mortality in high-risk patients having major surgery: a multicenter prospective randomized controlled interventional clinical study (IMPROVE-multi).
    Deutsche Gesellschaft für Anästhesiologie und lntensivmedizin (DGAI) (Nürnberg, Germany)

    • Personalized perioperative blood pressure management.
    Else Kröner-Fresenius-Stiftung (Bad Homburg, Germany)

Research Team

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