- Bioinformatik Facility
Tätigkeitsschwerpunkte
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Developing analysis pipeline for whole genome sequencing data (raw data QC, mapping, marking duplicate, coverage etc.)
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Developing mutation calling and annotation pipeline
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Analyzing next-generation sequencing data using popular NGS analysis tools like BWA, GATK, Samtools, Picard-tools, Bedtools, Bowtie2 etc.
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Analyzing next-generation sequencing data using the publicly available biological databases and servers like NCBI, PDB, dbSNP, KEGG, RefSeq, EntrezGene, GeneBank, Ensembl, Pfam, GO etc.
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Development of bioinformatics tools for RNA secondary structure analysis etc.
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High performance and parallelization computing (SGE, PBS etc.)
Lebenslauf
Publikationen
SARS-CoV-2 variant tracing within the first COVID-19 clusters in Northern Germany
Pfefferle S, Günther T, Kobbe R, Czech-Sioli M, Nörz D, Santer R, Oh J, Kluge S, Oestereich L, Peldschus K, Indenbirken D, Huang J, Grundhoff A, Aepfelbacher M, Knobloch J, Lütgehetmann M, Fischer N
CLIN MICROBIOL INFEC. 2021;27(1):.
Complete Genome Sequence of a SARS-CoV-2 Strain Isolated in Northern Germany
Pfefferle S, Huang J, Nörz D, Indenbirken D, Lütgehetmann M, Oestereich L, Günther T, Grundhoff A, Aepfelbacher M, Fischer N
Microbiology resource announcements. 2020;9(23):.
T-lymphocyte-specific knockout of IKK-2 or NEMO induces T17 cells in an experimental nephrotoxic nephritis mouse model
Guo L, Huang J, Chen M, Piotrowski E, Song N, Zahner G, Paust H, Alawi M, Geffers R, Thaiss F
FASEB J. 2019;33(2):2359-2371.
Changes in the composition of the upper respiratory tract microbial community in granulomatosis with polyangiitis
Lamprecht P, Fischer N, Huang J, Burkhardt L, Lütgehetmann M, Arndt F, Rolfs I, Kerstein A, Iking-Konert C, Laudien M
J AUTOIMMUN. 2019;97:29-39.
Emergence of ceftazidime/avibactam non-susceptibility in an MDR Klebsiella pneumoniae isolate
Both A, Büttner H, Huang J, Perbandt M, Belmar Campos C, Christner M, Maurer F, Kluge S, König C, Aepfelbacher M, Wichmann D, Rohde H
J ANTIMICROB CHEMOTH. 2017;72(9):2483-2488.
First report of Escherichia coli co-producing NDM-1 and OXA-232
Both A, Huang J, Kaase M, Hezel J, Wertheimer D, Fenner I, Günther T, Grundhoff A, Büttner H, Aepfelbacher M, Rohde H, Hentschke M
DIAGN MICR INFEC DIS. 2016;86(4):437-438.
Autoimmune Renal Disease Is Exacerbated by S1P-Receptor-1-Dependent Intestinal Th17 Cell Migration to the Kidney
Krebs C, Paust H, Krohn S, Koyro T, Brix S, Riedel J, Bartsch P, Wiech T, Meyer-Schwesinger C, Huang J, Fischer N, Busch C, Mittrücker H, Steinhoff U, Stockinger B, Perez L, Wenzel U, Janneck M, Steinmetz O, Gagliani N, Stahl R, Huber S, Turner J, Panzer U
IMMUNITY. 2016;45(5):1078-1092.
Analysing RNA-kinetics based on folding space abstraction
Huang J, Voß B
BMC BIOINFORMATICS. 2014;15(1):60.
Abstract folding space analysis based on helices
Huang J, Backofen R, Voß B
RNA. 2012;18(12):2135-2147.
RNAHeliCes -- Folding space analysis based on position aware structure abstraction
Huang J, Voß B
2011. In Proceedings of the German Conference on Bioinformatics 2011. RT--31.
Letzte Aktualisierung aus dem FIS: 01.03.2021 - 00:49 Uhr