Systems neuropharmacology of aversive learning
Our research focuses on neurotransmitter systems involved in aversive learning. In particular, we investigate how neurotransmitters such as Dopamine, Opioids and Cannabinoids contribute to emotional states of fear and anxiety. Moreover, we try to understand how these neurotransmitters influence the dynamics of learned fear and their impact on models of behavioural treatment of anxiety related disorders.
We employ basic learning paradigms such as classical conditioning, which enables translational neuroscientific research across species. To draw inferences on the neuropharmacological systems involved in these basic aversive learning processes, we combine pharmacological neuroimaging (fMRI) methods with psychophysiological measurements of threat responses.