Johannes Knobloch
Prof. Dr. med.
Johannes K.-M. Knobloch
  • Facharzt für Mikrobiologie, Virologie und Infektionsepidemiologie
  • 1.Arbeitsbereich
Deutsch (Muttersprache)





  • 2023
  • 2022
  • 2021
  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011
  • 2010
  • 2009
  • 2008
  • 2007
  • 2005
  • 2004
  • 2001
  • 2000

Integration of Sequencing and Epidemiologic Data for Surveillance of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infections in a Tertiary-Care Hospital
Czech-Sioli M, Günther T, Robitaille A, Roggenkamp H, Büttner H, Indenbirken D, Christner M, Lütgehetmann M, Knobloch J, Aepfelbacher M, Grundhoff A, Fischer N
CLIN INFECT DIS. 2023;76(3):e263-e273.

Overview of tight fit and infection prevention benefits of respirators (filtering face pieces)
Knobloch J, Franke G, Knobloch M, Knobling B, Kampf G
J HOSP INFECT. 2023;134:89-96.

Interlaboratory reproducibility of a touch-transfer assay for the assessment of antimicrobial surfaces
Mayr A, Knobloch J, Hinterberger G, Seewald V, Wille I, Kaltseis J, Knobling B, Klupp E, Samardzic E, Lass-Flörl C
J HOSP INFECT. 2023;134:1-6.

Absence of self-reported neuropsychiatric and somatic symptoms after Omicron variant SARS-CoV-2 breakthrough infections
Woo M, Mayer C, Brehm T, Andersen G, Weigel A, Löwe B, Lohse A, Addo M, Gerloff C, Knobloch J, Schulze Zur Wiesch J, Friese M
BRAIN COMMUN. 2023;5(2):fcad092.

The Transcription Factor SpoVG Is of Major Importance for Biofilm Formation of Staphylococcus epidermidis under In Vitro Conditions, but Dispensable for In Vivo Biofilm Formation
Benthien H, Fresenborg B, Pätzold L, Elhawy M, Huc-Brandt S, Beisswenger C, Krasteva-Christ G, Becker S, Molle V, Knobloch J, Bischoff M
INT J MOL SCI. 2022;23(6):.

Three Separate Spike Antigen Exposures by COVID-19 Vaccination or SARS-CoV-2 Infection Elicit Strong Humoral Immune Responses in Healthcare Workers
Brehm T, Ullrich F, Thompson M, Küchen J, Schwinge D, Spier A, Huber S, Knobloch J, Aepfelbacher M, Addo M, Lohse A, Lütgehetmann M, Schulze Zur Wiesch J
VACCINES-BASEL. 2022;10(7):.

High burden and diversity of carbapenemase-producing Enterobacterales observed in wastewater of a tertiary care hospital in Germany
Carlsen L, Büttner H, Christner M, Franke G, Indenbirken D, Knobling B, Lütgehetmann M, Knobloch J
INT J HYG ENVIR HEAL. 2022;242:.

Reading the Score of the Air-Change in Airborne Microbial Load in Contrast to Particulate Matter during Music Making
Knobling B, Franke G, Beike L, Dickhuth T, Knobloch J
INT J ENV RES PUB HE. 2022;19(16):.

Infectivity of SARS-CoV-2 on Inanimate Surfaces: Don't Trust Ct Value
Knobloch J, Pfefferle S, Lütgehetmann M, Nörz D, Klupp E, Belmar Campos C, Kluge S, Aepfelbacher M, Knobling B, Franke G
INT J ENV RES PUB HE. 2022;19(24):.

An FFP2 respirator mandate for healthcare workers to prevent transmission of SARS-CoV-2 lacks proportionality
Knobloch J, Popp W, Exner M, Walger P, Kampf G
J HOSP INFECT. 2022;130:146-147.

Evidence of surface contamination in hospital rooms occupied by patients infected with monkeypox, Germany, June 2022
Nörz D, Pfefferle S, Brehm T, Franke G, Grewe I, Knobling B, Aepfelbacher M, Huber S, Klupp E, Jordan S, Addo M, Schulze Zur Wiesch J, Schmiedel S, Lütgehetmann M, Knobloch J

Multi-organ assessment in mainly non-hospitalized individuals after SARS-CoV-2 infection: The Hamburg City Health Study COVID programme
Petersen E, Goßling A, Adam G, Aepfelbacher M, Behrendt C, Cavus E, Cheng B, Fischer N, Gallinat J, Kühn S, Gerloff C, Koch-Gromus U, Härter M, Hanning U, Huber T, Kluge S, Knobloch J, Kuta P, Schmidt-Lauber C, Lütgehetmann M, Magnussen C, Mayer C, Muellerleile K, Münch J, Nägele F, Petersen M, Renné T, Riedl K, Rimmele D, Schäfer I, Schulz H, Tahir E, Waschki B, Wenzel J, Zeller T, Ziegler A, Thomalla G, Twerenbold R, Blankenberg S
EUR HEART J. 2022;43(11):1124-1137.

Therapeutic Management of COVID-19 in a Pediatric Patient with Neurodegenerative CLN2 Disease and ICV-Enzyme Replacement Therapy: A Case Report
Schwering C, Apostolidou S, Deindl P, Christner M, Knobloch J, Herrmann J, Kobbe R, Schulz A, Singer D, Ebenebe C
NEUROPEDIATRICS. 2022;53(5):381-384.

Impact of Oral Rinsing with Octenidine Based Solution on SARS-CoV-2 Loads in Saliva of Infected Patients an Exploratory Study
Smeets R, Pfefferle S, Büttner H, Knobloch J, Lütgehetmann M
INT J ENV RES PUB HE. 2022;19(9):.

Erratum zu: Milde COVID-19-Verläufe bei Mitarbeitenden einer Universitätsklinik : Die „erste Welle“ am Universitätsklinikum Hamburg-Eppendorf
von Felden J, Brehm T, Schulze Zur Wiesch J, Addo M, Lohse A, Knobloch J, Koch T

Practical recommendations for routine cleaning and disinfection procedures in healthcare institutions: a narrative review
Assadian O, Harbarth S, Vos M, Knobloch J, Asensio A, Widmer A
J HOSP INFECT. 2021;113:104-114.

Telmisartan induces a specific gut microbiota signature which may mediate its antiobesity effect
Beckmann L, Künstner A, Freschi M, Huber G, Stölting I, Ibrahim S, Hirose M, Freitag M, Langan E, Matschl U, Galuska C, Fuchs B, Knobloch J, Busch H, Raasch W
PHARMACOL RES. 2021;170:.

SARS-CoV-2 Reinfection in a Healthcare Worker Despite the Presence of Detectable Neutralizing Antibodies
Brehm T, Pfefferle S, von Possel R, Kobbe R, Nörz D, Schmiedel S, Grundhoff A, Olearo F, Emmerich P, Robitaille A, Günther T, Braun P, Andersen G, Knobloch J, Addo M, Lohse A, Aepfelbacher M, Fischer N, Schulze Zur Wiesch J, Lütgehetmann M
VIRUSES-BASEL. 2021;13(4):.

Seroprevalence of SARS-CoV-2 antibodies among hospital workers in a German tertiary care center: A sequential follow-up study
Brehm T, Schwinge D, Lampalzer S, Schlicker V, Küchen J, Thompson M, Ullrich F, Huber S, Schmiedel S, Addo M, Lütgehetmann M, Knobloch J, Schulze Zur Wiesch J, Lohse A
INT J HYG ENVIR HEAL. 2021;232:.

Low SARS-CoV-2 infection rates and high vaccine-induced immunity among German healthcare workers at the end of the third wave of the COVID-19 pandemic
Brehm T, Thompson M, Ullrich F, Schwinge D, Addo M, Spier A, Knobloch J, Aepfelbacher M, Lohse A, Lütgehetmann M, Schulze Zur Wiesch J
INT J HYG ENVIR HEAL. 2021;238:.

Contamination of multi dose eyedrops in the intra and perioperative context
Daehn T, Schneider A, Knobloch J, Hellwinkel O, Spitzer M, Kromer R
SCI REP-UK. 2021;11(1):.

An automated room disinfection system using ozone is highly active against surrogates for SARS-CoV-2
Franke G, Knobling B, Brill F, Becker B, Klupp E, Belmar Campos C, Pfefferle S, Lütgehetmann M, Knobloch J
J HOSP INFECT. 2021;112:108-113.

Evaluation of the Effectiveness of Two Automated Room Decontamination Devices Under Real-Life Conditions
Knobling B, Franke G, Klupp E, Belmar Campos C, Knobloch J

Clinical performance and accuracy of a qPCR-based SARS-CoV-2 mass-screening workflow for healthcare-worker surveillance using pooled self-sampled gargling solutions: a cross-sectional study
Olearo F, Nörz D, Hoffman A, Grunwald M, Gatzemeyer K, Christner M, Both A, Campos C, Braun P, Andersen G, Pfefferle S, Zapf A, Aepfelbacher M, Knobloch J, Lütgehetmann M
J INFECTION. 2021;83(5):589-593.

SARS Coronavirus-2 variant tracing within the first Coronavirus Disease 19 clusters in northern Germany
Pfefferle S, Günther T, Kobbe R, Czech-Sioli M, Nörz D, Santer R, Oh J, Kluge S, Oestereich L, Peldschus K, Indenbirken D, Huang J, Grundhoff A, Aepfelbacher M, Knobloch J, Lütgehetmann M, Fischer N
CLIN MICROBIOL INFEC. 2021;27(1):130.e5-130.e8.

Development of the "Hamburg Best Practice Guidelines for ICV-Enzyme Replacement therapy (ERT) in CLN2 Disease" Based on 6 Years Treatment Experience in 48 Patients
Schwering C, Kammler G, Wibbeler E, Christner M, Knobloch J, Nickel M, Denecke J, Baehr M, Schulz A
J CHILD NEUROL. 2021;36(8):635-641.

Milde COVID-19-Verläufe bei Mitarbeitenden einer Universitätsklinik: Die „erste Welle“ am Universitätsklinikum Hamburg-Eppendorf
von Felden J, Brehm T, Schulze-Zur-Wiesch J, Addo M, Lohse A, Knobloch J, Koch T
BUNDESGESUNDHEITSBLATT. 2021;64(9):1165-1168.

High effectiveness of multimodal infection control interventions in preventing SARS−CoV−2 infections in healthcare professionals: a prospective longitudinal seroconversion study
Brehm T, Schwinge D, Lampalzer S, Schlicker V, Küchen J, Thompson M, Ullrich F, Huber S, Schmiedel S, Addo M, Lütgehetmann M, Knobloch J, Schulze zur Wiesch J, Lohse A
medRxiv BMJ. 2020.

Modulation of S. epidermidis-induced innate immune responses in neonatal whole blood
Tröger B, Heidemann M, Osthues I, Knaack D, Göpel W, Herting E, Knobloch J, Härtel C
J MICROBIOL IMMUNOL. 2020;53(2):240-249.

Implications of SARS-CoV-2 Infection and COVID-19 Crisis on Clinical Cancer Care: Report of the University Cancer Center Hamburg: Report of the University Cancer Center Hamburg
Weisel K, Morgner-Miehlke A, Petersen C, Fiedler W, Block A, Schafhausen P, Knobloch J, Bokemeyer C
ONCOL RES TREAT. 2020;43(6):307-313.

Hygienemanagement - Implementierung in Organisation und Prozesse
Knobloch J
2019. Pflegemanagement. Prölß J, Lux V, Bechtel P (Hrsg.). 1. Aufl. Berlin: Mwv Medizinisch Wissenschaftliche Verlagsges, 399-402.

Combined culture and metagenomic analyses reveal significant shifts in the composition of the cutaneous microbiome in psoriasis
Langan E, Künstner A, Miodovnik M, Zillikens D, Thaçi D, Baines J, Ibrahim S, Solbach W, Knobloch J
BRIT J DERMATOL. 2019;181(6):1254-1264.

The role of the microbiome in Psoriasis: moving from disease description to treatment selection?
Langan E, Griffiths C, Solbach W, Knobloch J, Zillikens D, Thaçi D
BRIT J DERMATOL. 2018;178(5):1020-1027.

Incidence of infections due to third generation cephalosporin-resistant - a prospective multicentre cohort study in six German university hospitals
Rohde A, Zweigner J, Wiese-Posselt M, Schwab F, Behnke M, Kola A, Obermann B, Knobloch J, Feihl S, Querbach C, Gebhardt F, Mischnik A, Ihle V, Schröder W, Armean S, Peter S, Tacconelli E, Hamprecht A, Seifert H, Vehreschild M, Kern W, Gastmeier P

"Life-like" assessment of antimicrobial surfaces by a new touch transfer assay displays strong superiority of a copper alloy compared to silver containing surfaces
Knobloch J, Tofern S, Kunz W, Schütze S, Riecke M, Solbach W, Wuske T
PLOS ONE. 2017;12(11):e0187442.

In vitro susceptibility to 19 agents other than β-lactams among third-generation cephalosporin-resistant Enterobacteriaceae recovered on hospital admission
Mischnik A, Baumert P, Hamprecht A, Rohde A, Peter S, Feihl S, Knobloch J, Gölz H, Kola A, Obermann B, Querbach C, Willmann M, Gebhardt F, Tacconelli E, Gastmeier P, Seifert H, Kern W
J ANTIMICROB CHEMOTH. 2017;72(5):1359-1363.

Susceptibility to cephalosporin combinations and aztreonam/avibactam among third-generation cephalosporin-resistant Enterobacteriaceae recovered on hospital admission
Mischnik A, Baumert P, Hamprecht A, Rohde A, Peter S, Feihl S, Knobloch J, Gölz H, Kola A, Obermann B, Querbach C, Willmann M, Gebhardt F, Tacconelli E, Gastmeier P, Seifert H, Kern W
INT J ANTIMICROB AG. 2017;49(2):239-242.

Hypertension and mild chronic kidney disease persist following severe haemolytic uraemic syndrome caused by Shiga toxin-producing Escherichia coli O104:H4 in adults
Derad I, Obermann B, Katalinic A, Eisemann N, Knobloch J, Sayk F, Wellhöner P, Lehnert H, Solbach W, Süfke S, Steinhoff J, Nitschke M
NEPHROL DIAL TRANSPL. 2016;31(1):95-103.

Colonization with third-generation cephalosporin-resistant Enterobacteriaceae on hospital admission: prevalence and risk factors
Hamprecht A, Rohde A, Behnke M, Feihl S, Gastmeier P, Gebhardt F, Kern W, Knobloch J, Mischnik A, Obermann B, Querbach C, Peter S, Schneider C, Schröder W, Schwab F, Tacconelli E, Wiese-Posselt M, Wille T, Willmann M, Seifert H, Zweigner J
J ANTIMICROB CHEMOTH. 2016;71(10):2957-63.

Comparison of Two Test Strategies for Clarification of Reactive Results for Anti-HBc in Blood Donors
Juhl D, Knobloch J, Görg S, Hennig H
TRANSFUS MED HEMOTH. 2016;43(1):37-43.

Susceptibility to penicillin derivatives among third-generation cephalosporin-resistant Enterobacteriaceae recovered on hospital admission
Mischnik A, Baumert P, Hamprecht A, Rohde A, Peter S, Feihl S, Knobloch J, Gölz H, Kola A, Obermann B, Querbach C, Willmann M, Gebhardt F, Tacconelli E, Gastmeier P, Seifert H, Kern W
DIAGN MICR INFEC DIS. 2016;87(1):71-73.

Management of Food-Related Diarrhea Outbreak in the Emergency Department: Lessons Learned from the German STEC O104:H4 Epidemic
Sayk F, Asselborn N, Eisemann N, Katalinic A, Metzner J, Wolfrum S, Fellermann K, Knobloch J, Nitschke M
BIOMED RES INT . 2015;2015:480680.

The effect of a bacterial contamination on the formation of capsular contracture with polyurethane breast implants in comparison with textured silicone implants:an animal study
Bergmann P, Tamouridis G, Lohmeyer J, Mauss K, Becker B, Knobloch J, Mailänder P, Siemers F
J PLAST RECONSTR AES. 2014;67(10):1364-70.

Whole-genome sequencing for risk assessment of long-term Shiga toxin-producing Escherichia coli
Knobloch J, Niemann S, Kohl T, Lindner U, Nitschke M, Sayk F, Solbach W
EMERG INFECT DIS. 2014;20(4):732-3.

Successful treatment of extensively drug-resistant Pseudomonas aeruginosa osteomyelitis using a colistin- and tobramycin-impregnated PMMA spacer
Krajewski J, Bode-Böger S, Tröger U, Martens-Lobenhoffer J, Mulrooney T, Mittelstädt H, Russlies M, Kirchner R, Knobloch J
INT J ANTIMICROB AG. 2014;44(4):363-6.

Detection of esterified cholesterol in murine Bruch's membrane wholemounts with a perfringolysin O-based cholesterol marker
Rudolf M, Mohi A, Dettbarn M, Miura Y, Aherrahrou Z, Ranjbar M, Mutus B, Knobloch J
INVEST OPHTH VIS SCI. 2014;55(8):4759-67.

Microevolution of the chromosomal region of acute disease antigen A (adaA) in the query (Q) fever agent Coxiella burnetii
Frangoulidis D, Splettstoesser W, Landt O, Dehnhardt J, Henning K, Hilbert A, Bauer T, Antwerpen M, Meyer H, Walter M, Knobloch J
PLOS ONE. 2013;8(1):e53440.

Lessons Learned From Outbreaks of Shiga Toxin Producing Escherichia coli
Hauswaldt S, Nitschke M, Sayk F, Solbach W, Knobloch J
CURR INFECT DIS REP. 2013;15(1):4-9.

Description of Riemerella columbipharyngis sp. nov., isolated from the pharynx of healthy domestic pigeons (Columba livia f. domestica), and emended descriptions of the genus Riemerella, Riemerella anatipestifer and Riemerella columbina
Rubbenstroth D, Ryll M, Hotzel H, Christensen H, Knobloch J, Rautenschlein S, Bisgaard M
INT J SYST EVOL MICR. 2013;63(Pt 1):280-7.

Evaluation of different diagnostic tools for the detection and identification of Riemerella anatipestifer
Rubbenstroth D, Ryll M, Knobloch J, Köhler B, Rautenschlein S
AVIAN PATHOL. 2013;42(1):17-26.

Validation of treatment strategies for enterohaemorrhagic Escherichia coli O104:H4 induced haemolytic uraemic syndrome:case-control study
Menne J, Nitschke M, Stingele R, Abu-Tair M, Beneke J, Bramstedt J, Bremer J, Brunkhorst R, Busch V, Dengler R, Deuschl G, Fellermann K, Fickenscher H, Gerigk C, Goettsche A, Greeve J, Hafer C, Hagenmüller F, Haller H, Herget-Rosenthal S, Hertenstein B, Hofmann C, Lang M, Kielstein J, Klostermeier U, Knobloch J, Kuehbacher M, Kunzendorf U, Lehnert H, Manns M, Menne T, Meyer T, Michael C, Münte T, Neumann-Grutzeck C, Nuernberger J, Pavenstaedt H, Ramazan L, Renders L, Repenthin J, Ries W, Rohr A, Rump L, Samuelsson O, Sayk F, Schmidt B, Schnatter S, Schöcklmann H, Schreiber S, von Seydewitz C, Steinhoff J, Stracke S, Suerbaum S, van de Loo A, Vischedyk M, Weissenborn K, Wellhöner P, Wiesner M, Zeissig S, Büning J, Schiffer M, Kuehbacher T
BMJ-BRIT MED J. 2012;345:e4565.

Association between azithromycin therapy and duration of bacterial shedding among patients with Shiga toxin-producing enteroaggregative Escherichia coli O104:H4
Nitschke M, Sayk F, Härtel C, Roseland R, Hauswaldt S, Steinhoff J, Fellermann K, Derad I, Wellhöner P, Büning J, Tiemer B, Katalinic A, Rupp J, Lehnert H, Solbach W, Knobloch J
JAMA-J AM MED ASSOC. 2012;307(10):1046-52.

Isolation and characterization of atypical Riemerella columbina strains from pigeons and their differentiation from Riemerella anatipestifer
Rubbenstroth D, Hotzel H, Knobloch J, Teske L, Rautenschlein S, Ryll M
VET MICROBIOL. 2011;147(1-2):103-12.

Abiotrophia defectiva endophthalmitis with retinal involvement and infiltrative keratitis: case report and review of the literature
Horstkotte M, Dobinsky S, Rohde H, Knobloch J, Hassenstein A, Kalitzky M, Richard G, Linke S
EUR J CLIN MICROBIOL. 2010;29(6):727-731.

Infektionsdiagnostik in der Pneumologie
Strassburg A, Dalhoff K, Engelmann I, Ewig S, Herth F, Knobloch J, Rohde G, Sahly H, Schaaf B, Lange C
PNEUMOLOGIE. 2010;64(5):291-9.

Regulation of biofilm formation by sigma B is a common mechanism in Staphylococcus epidermidis and is not mediated by transcriptional regulation of sarA.
Jäger S, Jonas B, Pfanzelt D, Horstkotte M, Rohde H, Mack D, Knobloch J
INT J ARTIF ORGANS. 2009;32(9):584-591.

Biofilm formation is not necessary for development of quinolone-resistant "persister" cells in an attached Staphylococcus epidermidis population
Knobloch J, Von Osten H, Horstkotte M, Rohde H, Mack D
INT J ARTIF ORGANS. 2008;31(9):752-760.

Expression and functional characterization of gfpmut3.1 and its unstable variants in Staphylococcus epidermidis.
Franke G, Dobinsky S, Mack D, Wang C, Sobottka I, Christner M, Knobloch J, Horstkotte M, Aepfelbacher M, Rohde H
J MICROBIOL METH. 2007;71(2):123-132.

Microbial interactions in Staphylococcus epidermidis biofilms
Mack D, Davies A, Harris L, Rohde H, Horstkotte M, Knobloch J
ANAL BIOANAL CHEM. 2007;387(2):399-408.

Polysaccharide intercellular adhesin or protein factors in biofilm accumulation of Staphylococcus epidermidis and Staphylococcus aureus isolated from prosthetic hip and knee joint infections.
Rohde H, Burandt E, Siemssen N, Frommelt L, Burdelski C, Wurster S, Scherpe S, Davies A, Harris L, Horstkotte M, Knobloch J, Ragunath C, Kaplan J, Mack D
BIOMATERIALS. 2007;28(9):1711-1720.

Induction of Staphylococcus epidermidis biofilm formation via proteolytic processing of the accumulation-associated protein by staphylococcal and host proteases.
Rohde H, Burdelski C, Bartscht K, Hussain M, Buck F, Horstkotte M, Knobloch J, Heilmann C, Herrmann M, Mack D
MOL MICROBIOL. 2005;55(6):1883-1895.

Evaluation of the BD PHOENIX automated microbiology system for detection of methicillin resistance in coagulase-negative staphylococci.
Horstkotte M, Knobloch J, Rohde H, Dobinsky S, Mack D
J CLIN MICROBIOL. 2004;42(11):5041-5046.

Mechanisms of biofilm formation in Staphylococcus epidermidis and Staphylococcus aureus: functional molecules, regulatory circuits, and adaptive responses
Mack D, Becker P, Chatterjee I, Dobinsky S, Knobloch J, Peters G, Rohde H, Herrmann M
INT J MED MICROBIOL. 2004;294(2-3):203-212.

Detection of virulence-associated genes not useful for discriminating between invasive and commensal Staphylococcus epidermidis strains from a bone marrow transplant unit.
Rohde H, Kalitzky M, Kröger N, Scherpe S, Horstkotte M, Knobloch J, Zander A, Mack D
J CLIN MICROBIOL. 2004;42(12):5614-5619.

Biofilm formation by Staphylococcus epidermidis depends on functional RsbU, an activator of the sigB operon: differential activation mechanisms due to ethanol and salt stress.
Knobloch J, Bartscht K, Sabottke A, Rohde H, Feucht H, Mack D
J BACTERIOL. 2001;183(8):2624-2633.

Identification of three essential regulatory gene loci governing expression of Staphylococcus epidermidis polysaccharide intercellular adhesin and biofilm formation
Mack D, Rohde H, Dobinsky S, Riedewald J, Nedelmann M, Knobloch J, Elsner H, Feucht H
INFECT IMMUN. 2000;68(7):3799-3807.

Letzte Aktualisierung aus dem FIS: 04.06.2023 - 00:34 Uhr