Jörg Flitsch
Prof. Dr. med.
Jörg Flitsch
  • Stellvertretender Klinikdirektor
  • Facharzt für Neurochirurgie



Hauptgebäude O10 , 2. Etage
Deutsch (Muttersprache)







Prevalence of Signs and Symptoms of Pseudotumor Cerebri Syndrome Before and After Transsphenoidal Surgery for Cushing's Disease - A Prospective Consecutive Case Series
Huckhagel T, Flitsch J, Rotermund R, Knospe V
EXP CLIN ENDOCR DIAB. 2020 [Epub ahead of print].

Clinical Situation, Therapy, and Follow-Up of Adult Craniopharyngioma: Report from the German Craniopharyngioma Registry
Mende K, Kellner T, Petersenn S, Honegger J, Evangelista-Zamora R, Droste M, Stalla G, Deutschbein T, Wang Y, Moskopp D, Knappe U, Schilbach K, Flitsch J
J CLIN ENDOCR METAB. 2020;105(1):.

Revived Attention for Adult Craniopharyngioma
Mende K, Pantel T, Flitsch J
EXP CLIN ENDOCR DIAB. 2020 [Epub ahead of print].

Bevacizumab in Aggressive Pituitary Adenomas - Experience with 3 Patients
Osterhage K, Rotermund R, Droste M, Dierlamm J, Saeger W, Petersenn S, Aberle J, Flitsch J
EXP CLIN ENDOCR DIAB. 2020 [Epub ahead of print].

Real-life analysis of 280 patients with surgically treated acromegaly: a single-center experience from 2008 to 2015
Rotermund R, Mader M, Burkhardt T, Matschke J, Aberle J, Krajewski K, Flitsch J, Rahvar A
Neurosurg Focus. 2020;48(6):E9.

Co-expression of intermediate filaments glial fibrillary acidic protein and cytokeratin in pituitary adenoma
Wiesnagrotzki N, Bernreuther C, Saeger W, Flitsch J, Glatzel M, Hagel C
PITUITARY. 2020 [Epub ahead of print].


Imaging flow cytometry facilitates multiparametric characterization of extracellular vesicles in malignant brain tumours
Ricklefs F, Maire C, Reimer R, Dührsen L, Kolbe K, Holz M, Schneider E, Rissiek A, Babayan A, Hille C, Pantel K, Krasemann S, Glatzel M, Heiland D, Flitsch J, Martens T, Schmidt N, Peine S, Breakefield X, Lawler S, Chiocca E, Fehse B, Giebel B, Görgens A, Westphal M, Lamszus K
Journal of extracellular vesicles. 2019;8(1):1588555.

Driver mutations in USP8 wild type Cushing's disease
Sbiera S, Perez-Rivas L, Taranets L, Weigand I, Flitsch J, Graf E, Monoranu C, Saeger W, Hagel C, Honegger J, Assie G, Hermus A, Stalla G, Herterich S, Ronchi C, Deutschbein T, Reincke M, Strom T, Popov N, Theodoropoulou M, Fassnacht M
NEURO-ONCOLOGY. 2019;21(10):1273-1283.

Impact of USP8 Gene Mutations on Protein Deregulation in Cushing Disease
Weigand I, Knobloch L, Flitsch J, Saeger W, Monoranu C, Höfner K, Herterich S, Rotermund R, Ronchi C, Buchfelder M, Glatzel M, Hagel C, Fassnacht M, Deutschbein T, Sbiera S
J CLIN ENDOCR METAB. 2019;104(7):2535-2546.

Non-secreting pituitary tumours characterised by enhanced expression of YAP/TAZ
Xekouki P, Lodge E, Matschke J, Santambrogio A, Apps J, Sharif A, Jacques T, Aylwin S, Prevot V, Li R, Flitsch J, Bornstein S, Theodoropoulou M, Andoniadou C
ENDOCR-RELAT CANCER. 2019;26(1):215-225.


Specificity of late-night salivary cortisol measured by automated electrochemiluminescence immunoassay for Cushing's disease in an obese population
Aberle J, Schulze Zur Wiesch C, Flitsch J, Veigel J, Schön G, Jung R, Reining F, Lautenbach A, Rotermund R, Riedel N
J ENDOCRINOL INVEST. 2018;41(11):1325-1331.

Symptomatic Vasospasms as a Life-Threatening Complication After Transsphenoidal Surgery
Osterhage K, Czorlich P, Burkhardt T, Rotermund R, Grzyska U, Flitsch J
WORLD NEUROSURG. 2018;110:180-188.

Development of Obesity-Associated Comorbidities Post Bariatric Surgery with a Special Focus on Diabetes Remission and Short-Term Relapse
Riedel N, Lautenbach A, Wienecke J, Mann O, Flitsch J, Aberle J
EXP CLIN ENDOCR DIAB. 2018;126(9):577-583.

Value of early postoperative random growth hormone levels and nadir growth hormone levels after oral glucose tolerance testing in acromegaly
Rotermund R, Burkhardt T, Rohani Z, Jung R, Aberle J, Flitsch J
GROWTH HORM IGF RES. 2018;41:64-70.


IgG4-related hypophysitis is highly prevalent among cases of histologically confirmed hypophysitis
Bernreuther C, Illies C, Flitsch J, Buchfelder M, Buslei R, Glatzel M, Saeger W
BRAIN PATHOL. 2017;27(6):839-845.

A 42-Year-Old Male with Diabetes Insipidus
Bremer Pais I, Bernreuther C, Minnemann T, Saeger W, Hagel C, Iking-Konert C, Aberle J, Flitsch J
BRAIN PATHOL. 2017;27(5):695-696.

Immunoprofiling of glial tumours of the neurohypophysis suggests a common pituicytic origin of neoplastic cells
Hagel C, Buslei R, Buchfelder M, Fahlbusch R, Bergmann M, Giese A, Flitsch J, Lüdecke D, Glatzel M, Saeger W
PITUITARY. 2017;20(2):211-217.

Intracystic interferon-alpha in pediatric craniopharyngioma patients: an international multicenter assessment on behalf of SIOPE and ISPN
Kilday J, Caldarelli M, Massimi L, Chen R, Lee Y, Liang M, Parkes J, Naiker T, van Veelen M, Michiels E, Mallucci C, Pettorini B, Meijer L, Dorfer C, Czech T, Diezi M, Schouten-van Meeteren A, Holm S, Gustavsson B, Benesch M, Müller H, Hoffmann A, Rutkowski S, Flitsch J, Escherich G, Grotzer M, Spoudeas H, Azquikina K, Capra M, Jiménez-Guerra R, MacDonald P, Johnston D, Dvir R, Constantini S, Kuo M, Yang S, Bartels U
NEURO-ONCOLOGY. 2017;19(10):1398-1407.

Pituicytoma-An outlook on possible targeted therapies
Mende K, Matschke J, Burkhardt T, Saeger W, Buslei R, Buchfelder M, Fahlbusch R, Westphal M, Flitsch J
CNS NEUROSCI THER. 2017;23(7):620-626.

Surgical treatment and outcome of TSH-producing pituitary adenomas
Rotermund R, Riedel N, Burkhardt T, Matschke J, Schmidt N, Aberle J, Flitsch J
ACTA NEUROCHIR. 2017;159(7):1219-1226.


Surgical management of pituitary metastases
Burkhardt T, Henze M, Kluth L, Westphal M, Schmidt N, Flitsch J
PITUITARY. 2016;19(1):11-18.

Health-related Quality of Life in Patients After Treatment of Cushing's Disease
Nader S, Burkhardt T, Vettorazzi E, Milian M, Aberle J, Petersenn S, Flitsch J
EXP CLIN ENDOCR DIAB. 2016;124(3):187-191.


Cavernous sinus sampling in patients with Cushing's disease
Burkhardt T, Flitsch J, van Leyen P, Sauer N, Aberle J, Grzyska U, Lüdecke D
Neurosurg Focus. 2015;38(2):E6.

Hippocampal and cerebellar atrophy in patients with Cushing's disease
Burkhardt T, Lüdecke D, Spies L, Wittmann L, Westphal M, Flitsch J
Neurosurg Focus. 2015;39(5):E5.

Surgery for pediatric craniopharyngiomas: is less more?
Flitsch J, Aberle J, Burkhardt T
J PEDIATR ENDOCRINOL METAB. 2015;28(1-2):27-33.

A pitfall in diagnosing Cushing's disease: ectopic ACTH-producing pituitary adenoma in the sphenoid sinus
Flitsch J, Schmid S, Bernreuther C, Winterberg B, Ritter M, Lehnert H, Burkhardt T
PITUITARY. 2015;18(2):279-82.

Treatment of Primary Hypophysitis in Germany
Honegger J, Buchfelder M, Schlaffer S, Droste M, Werner S, Strasburger C, Störmann S, Schopohl J, Kacheva S, Deutschbein T, Stalla G, Flitsch J, Milian M, Petersenn S
J CLIN ENDOCR METAB. 2015;100(9):3460-9.

Histological criteria for atypical pituitary adenomas - data from the German pituitary adenoma registry suggests modifications
Miermeister C, Petersenn S, Buchfelder M, Fahlbusch R, Lüdecke D, Hölsken A, Bergmann M, Knappe H, Hans V, Flitsch J, Saeger W, Buslei R
Acta Neuropathol Comm. 2015;3:50.

BRAF V600E analysis for the differentiation of papillary Craniopharyngiomas and Rathke's Cleft Cysts
Schweizer L, Capper D, Hölsken A, Fahlbusch R, Flitsch J, Buchfelder M, Herold-Mende C, von Deimling A, Buslei R

Insights into the Infiltrative Behavior of Adamantinomatous Craniopharyngioma in a New Xenotransplant Mouse Model
Stache C, Hölsken A, Schlaffer S, Hess A, Metzler M, Frey B, Fahlbusch R, Flitsch J, Buchfelder M, Buslei R
BRAIN PATHOL. 2015;25(1):1-10.


Expression analysis of GADD45γ, MEG3, and p8 in pituitary adenomas
Binse I, Ueberberg B, Sandalcioglu I, Flitsch J, Luedecke D, Mann K, Petersenn S
HORM METAB RES. 2014;46(9):644-50.

Dexamethasone PONV Prophylaxis Alters the Hypothalamic-Pituitary-Adrenal Axis After Transsphenoidal Pituitary Surgery
Burkhardt T, Rotermund R, Schmidt N, Kiefmann R, Flitsch J
J NEUROSURG ANESTH. 2014;26(3):216-9.

Hyponatremia after trans-sphenoidal surgery
Janneck M, Burkhardt T, Rotermund R, Sauer N, Flitsch J, Aberle J
MINERVA ENDOCRINOL. 2014;39(1):27-31.

Long-term follow-up and quality of life in patients with intracranial germinoma
Martens T, Rotermund R, Zu Eulenburg C, Westphal M, Flitsch J
NEUROSURG REV. 2014;37(3):445-451.

Non-functioning pituitary macroadenomas: Benefit from early growth hormone substitution after surgery
Sauer N, Flitsch J, Döing I, Dannheim V, Burkhardt T, Aberle J
GROWTH HORM IGF RES. 2014;24(2-3):71-5.

Cushing's Syndrome Due to a Corticotropin-Releasing Hormone- and Adrenocorticotrophic Hormone-Producing Neuroendocrine Pancreatic Tumor
Sauer N, Zur Wiesch C, Flitsch J, Saeger W, Klutmann S, Zustin J, Lübke A, Aberle J
ENDOCR PRACT. 2014;20(4):e53-7.

Frequency of AIP gene mutations in young patients with acromegaly: a registry-based study
Schöfl C, Honegger J, Droste M, Grussendorf M, Finke R, Plöckinger U, Berg C, Willenberg H, Lammert A, Klingmüller D, Jaursch-Hancke C, Tönjes A, Schneidewind S, Flitsch J, Bullmann C, Dimopoulou C, Stalla G, Mayr B, Hoeppner W, Schopohl J
J CLIN ENDOCR METAB. 2014;99(12):E2789-93.

Tight junction protein claudin-1 is differentially expressed in craniopharyngioma subtypes and indicates invasive tumor growth
Stache C, Hölsken A, Fahlbusch R, Flitsch J, Schlaffer S, Buchfelder M, Buslei R
NEURO-ONCOLOGY. 2014;16(2):256-64.

Reactive Pituitary Enlargement Mimicking a Sellar Mass
Sterkenburg A, Niekrens C, Hoffmann A, Warmuth-Metz M, Flitsch J, Müller H


DHEA(S)--a novel marker in Cushing's disease
Burkhardt T, Schmidt N, Vettorazzi E, Aberle J, Mengel M, Flitsch J
ACTA NEUROCHIR. 2013;155(3):479-84; discussion 484.

Adamantinomatous craniopharyngiomas express tumor stem cell markers in cells with activated Wnt signaling: further evidence for the existence of a tumor stem cell niche?
Hölsken A, Stache C, Schlaffer S, Flitsch J, Fahlbusch R, Buchfelder M, Buslei R


Metformin after bariatric surgery--an acid problem.
Aberle J, Reining F, Dannheim V, Flitsch J, Klinge A, Mann O
EXP CLIN ENDOCR DIAB. 2012;120(3):152-153.

Salivary cortisol as a diagnostic tool for Cushing's syndrome and adrenal insufficiency: improved screening by an automatic immunoassay.
Deutschbein T, Broecker-Preuss M, Flitsch J, Jaeger A, Althoff R, Walz M, Mann K, Petersenn S
EUR J ENDOCRINOL. 2012;166(4):613-618.

CSF fistulas after transsphenoidal pituitary surgery--a solved problem?
Malik M, Aberle J, Flitsch J
CENT EUR NEUROSURG. 2012;73(5):275-280.

DG3173 (somatoprim), a unique somatostatin receptor subtypes 2-, 4- and 5-selective analogue, effectively reduces GH secretion in human GH-secreting pituitary adenomas even in Octreotide non-responsive tumours.
Plöckinger U, Hoffmann U, Geese M, Lupp A, Buchfelder M, Flitsch J, Vajkoczy P, Jakob W, Saeger W, Schulz S, Dohrmann C
EUR J ENDOCRINOL. 2012;166(2):223-234.


Surgical strategies in childhood craniopharyngioma
Flitsch J, Müller H, Burkhardt T

Ectopic craniopharyngioma.
Kordes U, Flitsch J, Hagel C, Goebell E, Schwarz R, Herberhold T, von Bueren A, Rutkowski S, Müller H
KLIN PADIATR. 2011;223(3):176-177.


[Acromegaly-associated lesions of the nasal mucosa : Case report.]
Flitsch J, Lüdecke D, Saeger W, Veit J, Metternich F
HNO. 2009.


Genetic variation may influence obesity only under conditions of diet: analysis of three candidate genes.
Aberle J, Flitsch J, Beck N, Mann O, Busch P, Peitsmeier P, Beil F
MOL GENET METAB. 2008;95(3):188-191.

A 61-year-old man with hyponatremia.
Bernreuther C, Flitsch J, Lüdecke D, Hagel C
BRAIN PATHOL. 2008;18(2):283-287.

Hypophysectomy for prostate cancer: a revival of old knowledge?
Flitsch J, Bernreuther C, Hagel C, Lüdecke D
J NEUROSURG. 2008;109(4):760-764.


Diagnosis and treatment of an intramedullary cavernoma in a young male with an implanted cardiac pacemaker.
Fritzsche E, Flitsch J, Kucinski T, Lund G, Papavero L, Westphal M
ACTA NEUROCHIR. 2006;148(11):1213-1215.


Salivary cortisol measurement--a reliable method for the diagnosis of Cushing's syndrome.
Trilck M, Flitsch J, Lüdecke D, Jung R, Petersenn S
EXP CLIN ENDOCR DIAB. 2005;113(4):225-230.


Spondylodiscitis caused by occult endocarditis.
Flitsch J, Fritzsche E, Papavero L
ACTA NEUROCHIR. 2004;146(12):1377-1378.


HERG K(+) currents in human prolactin-secreting adenoma cells.
Bauer C, Wulfsen I, Schäfer R, Glassmeier G, Wimmers S, Flitsch J, Lüdecke D, Schwarz J
PFLUG ARCH EUR J PHY. 2003;445(5):589-600.

The use of postoperative ACTH levels as a marker for successful transsphenoidal microsurgery in Cushing's disease.
Flitsch J, Knappe U, Lüdecke D
ZBL NEUROCHIR. 2003;64(1):6-11.


Cavernous sinus sampling in selected cases of Cushing's disease.
Flitsch J, Lüdecke D, Knappe U, Grzyska U
EXP CLIN ENDOCR DIAB. 2002;110(7):329-335.


Cranial neuroendocrine carcinoma primarily diagnosed as malignant paraganglioma with rapid progress to a fatal outcome.
Flitsch J, Schröder F, Hagel C, Papavero L
ACTA NEUROCHIR. 2001;143(5):523-524.

Cushing's disease: a surgical view.
Lüdecke D, Flitsch J, Knappe U, Saeger W
J NEURO-ONCOL. 2001;54(2):151-166.


Transsphenoidal surgery for pituitary gigantism and galactorrhea in a 3.5 year old child.
Flitsch J, Lüdecke D, Stahnke N, Wiebel J, Saeger W
PITUITARY. 2000;2(4):261-267.

Emotional disorders in patients with different types of pituitary adenomas and factors affecting the diagnostic process.
Flitsch J, Spitzner S, Lüdecke D
EXP CLIN ENDOCR DIAB. 2000;108(7):480-485.

Surgical treatment of clinically nonsecreting pituitary adenomas in elderly patients.
Kurosaki M, Lüdecke D, Flitsch J, Saeger W
NEUROSURGERY. 2000;47(4):843-849.

The value of intraoperative cytology during transsphenoidal surgery for ACTH-secreting microadenoma.
Kurosaki M, Luedecke D, Knappe U, Flitsch J, Saeger W
ACTA NEUROCHIR. 2000;142(8):865-870.


Direct intraoperative micromethod for hormone measurements of pituitary tissue in Cushing's disease.
Flitsch J, Knappe U, Lüdecke D
SURG NEUROL. 1999;52(6):581-585.

Correlates of long-term hypocortisolism after transsphenoidal microsurgery for Cushing's disease.
Flitsch J, Lüdecke D, Knappe U, Saeger W
EXP CLIN ENDOCR DIAB. 1999;107(3):183-189.

Letzte Aktualisierung aus dem FIS: 19.01.2021 - 00:49 Uhr