Ansgar Lohse
Prof. Dr. med.
Ansgar W. Lohse
  • Klinikdirektor
  • Facharzt für Innere Medizin und Gastroenterologie


Hauptgebäude O10 , 2. Etage, Raumnummer
Deutsch (Muttersprache)







  • 2023
  • 2022
  • 2021
  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011
  • 2010

Adequate versus deep response to ursodeoxycholic acid in primary biliary cholangitis: To what extent and under what conditions is normal ALP level associated with complication-free survival gain?

HEPATOLOGY. 2023 [Epub ahead of print].

Cancer associated fibroblasts induce proliferation and therapeutic resistance to everolimus in neuroendocrine tumors through STAT3 activation
Amin T, Viol F, Krause J, Fahl M, Eggers C, Awwad F, Schmidt B, Benten D, Ungefroren H, Fraune C, Clauditz T, Sauter G, Izbicki J, Lohse A, Huber S, Schrader J
NEUROENDOCRINOLOGY. 2023;113(5):501-518.

Comparative analysis of characteristics and outcomes in hospitalized COVID-19 patients infected with different SARS-CoV-2 variants between January 2020 and April 2022 - A retrospective single-center cohort study
Brehm T, Heyer A, Woo M, Fischer M, van der Meirschen M, Wichmann D, Jarczak D, Roedl K, Schmiedel S, Addo M, Lütgehetmann M, Christner M, Huber S, Lohse A, Kluge S, Schulze Zur Wiesch J
J INFECT PUBLIC HEAL. 2023;16(11):1806-1812.

FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2
Brevini T, Maes M, Webb G, John B, Fuchs C, Buescher G, Wang L, Griffiths C, Brown M, Scott W, Pereyra-Gerber P, Gelson W, Brown S, Dillon S, Muraro D, Sharp J, Neary M, Box H, Tatham L, Stewart J, Curley P, Pertinez H, Forrest S, Mlcochova P, Varankar S, Darvish-Damavandi M, Mulcahy V, Kuc R, Williams T, Heslop J, Rossetti D, Tysoe O, Galanakis V, Vila-Gonzalez M, Crozier T, Bargehr J, Sinha S, Upponi S, Fear C, Swift L, Saeb-Parsy K, Davies S, Wester A, Hagström H, Melum E, Clements D, Humphreys P, Herriott J, Kijak E, Cox H, Bramwell C, Valentijn A, Illingworth C, , Dahman B, Bastaich D, Ferreira R, Marjot T, Barnes E, Moon A, Barritt A, Gupta R, Baker S, Davenport A, Corbett G, Gorgoulis V, Buczacki S, Lee J, Matheson N, Trauner M, Fisher A, Gibbs P, Butler A, Watson C, Mells G, Dougan G, Owen A, Lohse A, Vallier L, Sampaziotis F
NATURE. 2023;615(7950):134-142.

Frequency of IRF5+ dendritic cells is associated with the TLR7-induced inflammatory cytokine response in SARS-CoV-2 infection
Cords L, Woost R, Kummer S, Brehm T, Kluge S, Schmiedel S, Jordan S, Lohse A, Altfeld M, Addo M, Schulze Zur Wiesch J, Beisel C
CYTOKINE. 2023;162:.

Psychological risk factors for Long COVID and their modification: study protocol of a three-arm, randomised controlled trial (SOMA.COV)
Engelmann P, Büchel C, Frommhold J, Klose H, Lohse A, Maehder K, Nestoriuc Y, Scherer M, Suling A, Toussaint A, Weigel A, Zapf A, Löwe B

Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22
Giannou A, Kempski J, Shiri A, Lücke J, Zhang T, Zhao L, Zazara D, Cortesi F, Riecken K, Amezcua Vesely M, Low J, Xu H, Kaffe E, Garcia-Perez L, Agalioti T, Yamada Y, Jungraithmayr W, Zigmond E, Karstens K, Steglich B, Wagner J, Konczalla L, Carambia A, Schulze K, von Felden J, May P, Briukhovetska D, Bedke T, Brockmann L, Starzonek S, Lange T, Koch C, Riethdorf S, Pelczar P, Böttcher M, Sabihi M, Huber F, Reeh M, Grass J, Wahib R, Seese H, Stüben B, Fard-Aghaie M, Duprée A, Scognamiglio P, Plitzko G, Meiners J, Soukou S, Wittek A, Manthey C, Maroulis I, Arck P, Perez D, Gao B, Zarogiannis S, Strowig T, Pasqualini R, Arap W, Gosálvez J, Kobold S, Prinz I, Guse A, Tachezy M, Ghadban T, Heumann A, Li J, Melling N, Mann O, Izbicki J, Pantel K, Schumacher U, Lohse A, Flavell R, Gagliani N, Huber S
IMMUNITY. 2023;56(1):125-142.e12.

Analysis of the humoral and cellular response after the third COVID-19 vaccination in patients with autoimmune hepatitis
Hartl J, Rüther D, Duengelhoef P, Brehm T, Steinmann S, Weltzsch J, Glaser F, Sterneck M, Sebode M, Weiler-Normann C, Lütgehetmann M, Schaub G, Haag F, Schramm C, Schulze Zur Wiesch J, Lohse A
LIVER INT. 2023;43(2):393-400.

Tecovirimat therapy for severe monkeypox infection: Longitudinal assessment of viral titers and clinical response pattern-A first case-series experience
Hermanussen L, Grewe I, Tang H, Nörz D, Bal L, Pfefferle S, Unger S, Hoffmann C, Berzow D, Kohsar M, Aepfelbacher M, Lohse A, Addo M, Lütgehetmann M, Schulze zur Wiesch J, Schmiedel S
J MED VIROL. 2023;95(1):e28181.

Non-organ-specific autoantibodies with unspecific patterns are a frequent para-infectious feature of chronic hepatitis D
Hermanussen L, Lampalzer S, Bockmann J, Ziegler A, Piecha F, Dandri M, Pischke S, Haag F, Lohse A, Lütgehetmann M, Weiler-Normann C, Zur Wiesch J
FRONT MED-LAUSANNE. 2023;10:1169096.

Clinical Outcomes of SARS-CoV-2 Breakthrough Infections in Liver Transplant Recipients during the Omicron Wave
Herting A, Jahnke-Triankowski J, Harberts A, Schaub G, Lütgehetmann M, Ruether D, Fischer L, Addo M, Lohse A, Schulze Zur Wiesch J, Sterneck M
VIRUSES-BASEL. 2023;15(2):.

MELD-Lactate Predicts Poor Outcome in Variceal Bleeding in Cirrhosis
Horvatits T, Mahmud N, Serper M, Seiz O, Reher D, Drolz A, Sarnast N, Gu W, Erasmus H, Allo G, Ferstl P, Wittmann S, Piecha F, Groth S, Zeuzem S, Schramm C, Huber S, Rösch T, Lohse A, Trebicka J, Ogola G, Asrani S, Kluwe J
DIGEST DIS SCI. 2023;68(3):1042-1050.

A prospective pilot study of a gluten-free diet for primary sclerosing cholangitis and associated colitis
Liwinski T, Hübener S, Henze L, Hübener P, Heinemann M, Tetzlaff M, Hiller M, Jagemann B, Surabattula R, Leeming D, Karsdal M, Monguzzi E, Schachschal G, Rösch T, Bang C, Franke A, Lohse A, Schuppan D, Schramm C
ALIMENT PHARM THER. 2023;57(2):224-236.

Intestinal IL-1β Plays a Role in Protecting against SARS-CoV-2 Infection
Lücke J, Heinrich F, Malsy J, Meins N, Schnell J, Böttcher M, Nawrocki M, Zhang T, Bertram F, Sabihi M, Kempski J, Blankenburg T, Duprée A, Reeh M, Wolter S, Mann O, Izbicki J, Lohse A, Gagliani N, Lütgehetmann M, Bunders M, Altfeld M, Sauter G, Giannou A, Krasemann S, Ondruschka B, Huber S
J IMMUNOL. 2023;211(6):1052-1061.

Diagnosis and management of autoimmune hepatitis
Muratori L, Lohse A, Lenzi M
BMJ-BRIT MED J. 2023;380:.

Accuracy of controlled attenuation parameter measurement for the detection of steatosis in autoimmune liver diseases
Steinmann S, Hartl J, Weidemann S, Füssel K, Kroll C, Sebode M, Lohse A, Schramm C
JHEP REP. 2023;5(12):100898.

Improving quality of life in patients with rare autoimmune liver diseases by structured peer-delivered support (Q.RARE.LI): study protocol for a transnational effectiveness-implementation hybrid trial
Uhlenbusch N, Bal A, Balogh B, Braun A, Geerts A, Hirschfield G, Janik M, Lohse A, Milkiewicz P, Papp M, Poppe C, Schramm C, Löwe B
BMC PSYCHIATRY. 2023;23(1):193.

Autoimmune Hepatitis: Von Autoantikörpern bis Zirrhose
Weltzsch J, Ziegler A, Lohse A
INNERE MED. 2023;64(7):655-667.

Multicytokine-producing CD4+ T cells characterize the livers of patients with NASH
Woestemeier A, Scognamiglio P, Zhao Y, Wagner J, Muscate F, Casar C, Siracusa F, Cortesi F, Agalioti T, Müller S, Sagebiel A, Konczalla L, Wahib R, Karstens K, Giannou A, Duprée A, Wolter S, Wong M, Mühlig A, Bielecka A, Bansal V, Zhang T, Mann O, Puelles V, Huber T, Lohse A, Izbicki J, Palm N, Bonn S, Huber S, Gagliani N
JCI INSIGHT. 2023;8(1):.

Sotrovimab in Hospitalized Patients with SARS-CoV-2 Omicron Variant Infection: a Propensity Score-Matched Retrospective Cohort Study
Woo M, Brehm T, Fischer M, Heyer A, Wichmann D, Jordan S, Nörz D, Lütgehetmann M, Addo M, Lohse A, Schmiedel S, Kluge S, Schulze Zur Wiesch J
MICROBIOL SPECTR. 2023;11(1):.

Absence of self-reported neuropsychiatric and somatic symptoms after Omicron variant SARS-CoV-2 breakthrough infections
Woo M, Mayer C, Brehm T, Andersen G, Weigel A, Löwe B, Lohse A, Addo M, Gerloff C, Knobloch J, Schulze Zur Wiesch J, Friese M
BRAIN COMMUN. 2023;5(2):fcad092.

Confidence in treatment is contributing to quality of life in autoimmune liver diseases. The results of ERN RARE-LIVER online survey
Wunsch E, Krause L, Gevers T, Schramm C, Janik M, Krawczyk M, Willemse J, Uhlenbusch N, Löwe B, Lohse A, Milkiewicz P
LIVER INT. 2023;43(2):381-392.

Treatment responses and outcomes in patients with autoimmune hepatitis and concomitant features of non-alcoholic fatty liver disease
Zachou K, Azariadis K, Lytvyak E, Snijders R, Takahashi A, Gatselis N, Robles M, Andrade R, Schramm C, Lohse A, Tanaka A, Drenth J, Montano-Loza A, Dalekos G
JHEP REP. 2023;5(8):.

Bile duct colonization with Enterococcus sp. associates with disease progression in Primary Sclerosing Cholangitis
Zigmond E, Zecher B, Bartels A, Ziv-Baran T, Rösch T, Schachschal G, Lohse A, Ehlken H, Schramm C
CLIN GASTROENTEROL H. 2023;21(5):1223-1232.e3.

Advances in genetic, epigenetic and environmental aspects of rare liver diseases
Andersson E, Lohse A
EUR J MED GENET. 2022;65(2):.

Metabolic Syndrome Is Associated with Impaired Survival after Surgery for Pancreatic Neuroendocrine Tumors
Awwad F, Ozga A, Amin T, Schlueter C, Kailani S, Perez D, Wolter S, Sauter G, Izbicki J, Lohse A, Schrader J
NEUROENDOCRINOLOGY. 2022;112(12):1225-1236.

Diagnosis of abdominal tuberculosis by mini-laparoscopy
Brehm T, Schmiedel S, Lohse A
INFECTION. 2022;50(4):1049-1050.

Three Separate Spike Antigen Exposures by COVID-19 Vaccination or SARS-CoV-2 Infection Elicit Strong Humoral Immune Responses in Healthcare Workers
Brehm T, Ullrich F, Thompson M, Küchen J, Schwinge D, Spier A, Huber S, Knobloch J, Aepfelbacher M, Addo M, Lohse A, Lütgehetmann M, Schulze Zur Wiesch J
VACCINES-BASEL. 2022;10(7):.

SARS-CoV-2 in Pediatric Liver Transplant Recipients: The European Experience
Buescher G, Sebode M, Marjot T, Webb G, Moon A, Barnes E, Barritt A, Cananzi M, Lohse A, Jørgensen M, McLin V
J PEDIATR GASTR NUTR. 2022;74(2):e41-e42.

Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022
de Kleine R, Lexmond W, Buescher G, Sturm E, Kelly D, Lohse A, Lenz D, Jørgensen M

SARS-CoV-2 vaccination response in patients with autoimmune hepatitis and autoimmune cholestatic liver disease
Duengelhoef P, Hartl J, Rüther D, Steinmann S, Brehm T, Weltzsch J, Glaser F, Schaub G, Sterneck M, Sebode M, Weiler-Normann C, Addo M, Lütgehetmann M, Haag F, Schramm C, Schulze Zur Wiesch J, Lohse A
UNITED EUR GASTROENT. 2022;10(3):319-329.

Risk factors for worsening of somatic symptom burden in a prospective cohort during the COVID-19 pandemic
Engelmann P, Löwe B, Brehm T, Weigel A, Ullrich F, Addo M, Schulze zur Wiesch J, Lohse A, Toussaint A
FRONT PSYCHOL. 2022;13:1022203.

Predictors of somatic symptom burden in healthcare professionals during the COVID-19 pandemic: an 8-week follow-up study
Engelmann P, Toussaint A, Addo M, Brehm T, Lohse A, Weigel A, Thompson M, Löwe B
J MENT HEALTH. 2022 [Epub ahead of print];1-11.

Equal Efficacy and Safety Profile in Elderly Patients with Hepatocellular Carcinoma Receiving Palliative Treatment
Fründt T, Casar C, von Felden J, Schöler U, Priebe M, Kraczyk J, Ahrend H, Salamon J, Adam G, Huber S, Lohse A, Wege H, Schulze K
CANCERS. 2022;14(3):.

Low incidence of colonic complications after severe Shiga toxin-producing E. coli O104:H4 infection
Fründt T, Leuffert J, Groth S, Rösch T, Steurer S, Lohse A, Ullrich S, Lüth S
Z GASTROENTEROL. 2022;60(7):1104-1110.

Prevalence and risk factors of undiagnosed diabetes mellitus among gastroenterological patients: a HbA1c-based single center experience – Prevalence of undiagnosed diabetes in gastroenterological patients
Fründt T, Schröder N, Hölzemer A, Pinnschmidt H, de Heer J, Behrends B, Renne T, Lautenbach A, Lohse A, Schrader J
Z GASTROENTEROL. 2022;60(9):1306-1313.

Circulating tumor cells as a preoperative risk marker for occult metastases in patients with resectable cholangiocarcinoma
Fründt T, von Felden J, Krause J, Heumann A, Li J, Riethdorf S, Pantel K, Huber S, Lohse A, Wege H, Schulze K
FRONT ONCOL. 2022;12:.

Humoral and Cellular Immune Response After Third and Fourth SARS-CoV-2 mRNA Vaccination in Liver Transplant Recipients
Harberts A, Schaub G, Ruether D, Duengelhoef P, Brehm T, Karsten H, Fathi A, Jahnke-Triankowski J, Fischer L, Addo M, Haag F, Lütgehetmann M, Lohse A, Schulze zur Wiesch J, Sterneck M
CLIN GASTROENTEROL H. 2022;20(11):2558-2566.e5.

Long-term outcome after living donor liver transplantation compared to donation after brain death in autoimmune liver diseases: Experience from the European Liver Transplant Registry
Heinemann M, Liwinski T, Adam R, Berenguer M, Mirza D, Malek-Hosseini S, Heneghan M, Lodge P, Pratschke J, Boudjema K, Paul A, Zieniewicz K, Fronek J, Mehrabi A, Acarli K, Tokat Y, Coker A, Yilmaz S, Karam V, Duvoux C, Lohse A, Schramm C
AM J TRANSPLANT. 2022;22(2):626-633.

Hepatische Granulome – eine diagnostische Herausforderung
Horst L, Weidemann S, Lohse A, Sebode M
Z RHEUMATOL. 2022;81(7):567-576.

Einführung "Symposium Infektionen und Gesellschaft - was wir gelernt haben"
Lohse A, Mettenleiter T
2022. Infektionen und Gesellschaft. Lohse A, Mettenleiter T (Hrsg.). 1. Aufl. Berlin: Springer Spektrum, Berlin, Heidelberg, 3-8.

Consensus recommendations for histological criteria of autoimmune hepatitis from the International AIH Pathology Group: Results of a workshop on AIH histology hosted by the European Reference Network on Hepatological Diseases and the European Society of Pathology
Lohse A, Sebode M, Bhathal P, Clouston A, Dienes H, Jain D, Gouw A, Guindi M, Kakar S, Kleiner D, Krech T, Lackner C, Longerich T, Saxena R, Terracciano L, Washington K, Weidemann S, Hübscher S, Tiniakos D
LIVER INT. 2022;42(5):1058-1069.

Persistent SOMAtic symptoms ACROSS diseases - from risk factors to modification: scientific framework and overarching protocol of the interdisciplinary SOMACROSS research unit (RU 5211)
Löwe B, Andresen V, Van den Bergh O, Huber T, von dem Knesebeck O, Lohse A, Nestoriuc Y, Schneider G, Schneider S, Schramm C, Ständer S, Vettorazzi E, Zapf A, Shedden-Mora M, Toussaint A
BMJ OPEN. 2022;12(1):.

Persistence of gastrointestinal symptoms in irritable bowel syndrome and ulcerative colitis: study protocol for a three-arm randomised controlled trial (SOMA.GUT-RCT)
Löwe B, Nestoriuc Y, Andresen V, Vettorazzi E, Zapf A, Hübener S, Maehder K, Peters L, Lohse A
BMJ OPEN. 2022;12(6):.

Disturbed lipid and amino acid metabolisms in COVID-19 patients
Masoodi M, Peschka M, Schmiedel S, Haddad M, Frye M, Maas C, Lohse A, Huber S, Kirchhof P, Nofer J, Renné T
J MOL MED. 2022;100(4):555-568.

Risk factors and outcomes associated with recurrent autoimmune hepatitis following liver transplantation
Montano-Loza A, Ronca V, Ebadi M, Hansen B, Hirschfield G, Elwir S, Alsaed M, Milkiewicz P, Janik M, Marschall H, Burza M, Efe C, Calışkan A, Harputluoglu M, Kabaçam G, Terrabuio D, de Quadros Onofrio F, Selzner N, Bonder A, Parés A, Llovet L, Akyıldız M, Arikan C, Manns M, Taubert R, Weber A, Schiano T, Haydel B, Czubkowski P, Socha P, Ołdak N, Akamatsu N, Tanaka A, Levy C, Martin E, Goel A, Sedki M, Jankowska I, Ikegami T, Rodriguez M, Sterneck M, Weiler-Normann C, Schramm C, Donato M, Lohse A, Andrade R, Patwardhan V, van Hoek B, Biewenga M, Kremer A, Ueda Y, Deneau M, Pedersen M, Mayo M, Floreani A, Burra P, Secchi M, Beretta-Piccoli B, Sciveres M, Maggiore G, Jafri S, Debray D, Girard M, Lacaille F, Lytvyak E, Mason A, Heneghan M, Oo Y
J HEPATOL. 2022;77(1):84-97.

Inflammatory type 2 conventional dendritic cells contribute to murine and human cholangitis
Müller A, Casar C, Preti M, Krzikalla D, Gottwick C, Averhoff P, Rosenstiel P, Gelderblom M, Altfeld M, Lohse A, Steinmann S, Sebode M, Krause J, Schwinge D, Schramm C, Carambia A, Herkel J
J HEPATOL. 2022;77(6):1532-1544.

Systematic review of response criteria and endpoints in autoimmune hepatitis by the International Autoimmune Hepatitis Group
Pape S, Snijders R, Gevers T, Chazouilleres O, Dalekos G, Hirschfield G, Lenzi M, Trauner M, Manns M, Vierling J, Montano-Loza A, Lohse A, Schramm C, Drenth J, Heneghan M
J HEPATOL. 2022;76(4):841-849.

Localization defines streptozotocin/5-FU response in primary pancreatic neuroendocrine tumours
Reher D, Fehrenbach U, Radiology D, Radiology D, Henes F, Cremer B, Hörsch D, Izbicki J, Lohse A, Rinke A, Schrader J
NEUROENDOCRINOLOGY. 2022;112(6):595-605.

SARS-CoV2-specific humoral and T-cell immune response after second vaccination in liver cirrhosis and transplant patients
Ruether D, Schaub G, Duengelhoef P, Haag F, Brehm T, Fathi A, Wehmeyer M, Jahnke-Triankowski J, Mayer L, Hoffmann A, Fischer L, Addo M, Lütgehetmann M, Lohse A, Schulze Zur Wiesch J, Sterneck M
CLIN GASTROENTEROL H. 2022;20(1):162-172.e9.

Autoimmune hepatitis and COVID-19: No increased risk for AIH after vaccination but reduced care
Rüther D, Weltzsch J, Schramm C, Sebode M, Lohse A
J HEPATOL. 2022;77(1):250-251.

Tolerance and autoimmunity in the liver
Schramm C, Oo Y, Lohse A
SEMIN IMMUNOPATHOL. 2022;44(4):393-395.

B cells in autoimmune hepatitis: bystanders or central players?
Schultheiß C, Steinmann S, Lohse A, Binder M
SEMIN IMMUNOPATHOL. 2022;44(4):411-427.

Histological spectrum of autoimmune hepatitis-reply to Fujiwara K. et al
Sebode M, Lohse A, Hübscher S, Tiniakos D
LIVER INT. 2022;42(7):1704-1705.

Increased concentrations of conjugated bile acids are associated with osteoporosis in PSC patients
Stürznickel J, Behler-Janbeck F, Baranowsky A, Schmidt T, Schwinge D, John C, Lohse A, Schramm C, Heeren J, Schinke T, Amling M
SCI REP-UK. 2022;12(1):.

Quantification of polyreactive immunoglobulin G facilitates the diagnosis of autoimmune hepatitis
Taubert R, Engel B, Diestelhorst J, Hupa-Breier K, Behrendt P, Baerlecken N, Sühs K, Janik M, Zachou K, Sebode M, Schramm C, Londoño M, Habes S, Oo Y, Lalanne C, Pape S, Schubert M, Hust M, Dübel S, Thevis M, Jonigk D, Beimdiek J, Buettner F, Drenth J, Muratori L, Adams D, Dyson J, Renand A, Graupera I, Lohse A, Dalekos G, Milkiewicz P, Stangel M, Maasoumy B, Witte T, Wedemeyer H, Manns M, Jaeckel E
HEPATOLOGY. 2022;75(1):13-27.

Psychosoziale Unterstützung von Menschen mit Colitis ulcerosa und Reizdarmsyndrom: eine Machbarkeitsstudie zu Bedarf, Fokus und Durchführbarkeit
Uhlenbusch N, Manthey C, Nestoriuc Y, Andresen V, Lohse A, Löwe B
PSYCHOTHER PSYCH MED. 2022;72(11):481-490.

Novel preclinical gastroenteropancreatic neuroendocrine neoplasia models demonstrate the feasibility of mutation-based targeted therapy
Viol F, Sipos B, Fahl M, Clauditz T, Amin T, Kriegs M, Nieser M, Izbicki J, Huber S, Lohse A, Schrader J
CELL ONCOL. 2022;45(6):1401-1419.

High risk of complications and acute-on-chronic liver failure in cirrhosis patients with acute pancreatitis
Vogel M, Ehlken H, Kluge S, Roesch T, Lohse A, Huber S, Sterneck M, Hübener P
EUR J INTERN MED. 2022;102:54-62.

Erratum zu: Milde COVID-19-Verläufe bei Mitarbeitenden einer Universitätsklinik : Die „erste Welle“ am Universitätsklinikum Hamburg-Eppendorf
von Felden J, Brehm T, Schulze Zur Wiesch J, Addo M, Lohse A, Knobloch J, Koch T

Molecular consequences of SARS-CoV-2 liver tropism
Wanner N, Andrieux G, Badia-I-Mompel P, Edler C, Pfefferle S, Lindenmeyer M, Schmidt-Lauber C, Czogalla J, Wong M, Okabayashi Y, Braun F, Lütgehetmann M, Meister E, Lu S, Noriega M, Günther T, Grundhoff A, Fischer N, Bräuninger H, Lindner D, Westermann D, Haas F, Roedl K, Kluge S, Addo M, Huber S, Lohse A, Reiser J, Ondruschka B, Sperhake J, Saez-Rodriguez J, Boerries M, Hayek S, Aepfelbacher M, Scaturro P, Puelles V, Huber T
NAT METAB. 2022;4(3):310-319.

Stop of proton-pump inhibitor treatment in patients with liver cirrhosis (STOPPIT): study protocol for a prospective, multicentre, controlled, randomized, double-blind trial
Wehmeyer M, Horvatits T, Buchholz A, Krause L, Walter S, Zapf A, Lohse A, Kluwe J
TRIALS. 2022;23(1):302.

Frequent detection of functional hyposplenism via assessment of pitted erythrocytes in patients with advanced liver cirrhosis
Wehmeyer M, Sekhri H, Wroblewski R, Galante A, Meyer T, Lohse A, Schulze Zur Wiesch J
PLOS ONE. 2022;17(7):.

Einstellungen gegenüber der COVID-19-Impfung im Vergleich zur Grippeschutzimpfung bei Krankenhauspersonal
Weigel A, Brehm T, Schulze zur Wiesch J, Vogt B, Lohse A, Löwe B
PSYCHOTHER PSYCH MED. 2022;72(8):382-385.

High Rates of Liver Cirrhosis and Hepatocellular Carcinoma in Chronic Hepatitis B Patients with Metabolic and Cardiovascular Comorbidities
Bockmann J, Kohsar M, Murray J, Hamed V, Dandri-Petersen M, Lüth S, Lohse A, Schulze-Zur-Wiesch J

Patient Characteristics and Clinical Course of COVID-19 Patients Treated at a German Tertiary Center during the First and Second Waves in the Year 2020
Brehm T, Heyer A, Roedl K, Jarczak D, Nierhaus A, Nentwich M, van der Meirschen M, Schultze A, Christner M, Fiedler W, Kröger N, Huber T, Klose H, Sterneck M, Jordan S, Kreuels B, Schmiedel S, Addo M, Huber S, Lohse A, Kluge S, Schulze Zur Wiesch J
J CLIN MED. 2021;10(11):.

Lower Levels of Transaminases but Higher Levels of Serum Creatinine in Patients with Acute Hepatitis E in Comparison to Patients with Hepatitis A
Brehm T, Mazaheri O, Horvatits T, Lütgehetmann M, Schulze Zur Wiesch J, Lohse A, Polywka S, Pischke S
PATHOGENS. 2021;10(1):60.

SARS-CoV-2 Reinfection in a Healthcare Worker Despite the Presence of Detectable Neutralizing Antibodies
Brehm T, Pfefferle S, von Possel R, Kobbe R, Nörz D, Schmiedel S, Grundhoff A, Olearo F, Emmerich P, Robitaille A, Günther T, Braun P, Andersen G, Knobloch J, Addo M, Lohse A, Aepfelbacher M, Fischer N, Schulze Zur Wiesch J, Lütgehetmann M
VIRUSES-BASEL. 2021;13(4):.

Seroprevalence of SARS-CoV-2 antibodies among hospital workers in a German tertiary care center: A sequential follow-up study
Brehm T, Schwinge D, Lampalzer S, Schlicker V, Küchen J, Thompson M, Ullrich F, Huber S, Schmiedel S, Addo M, Lütgehetmann M, Knobloch J, Schulze Zur Wiesch J, Lohse A
INT J HYG ENVIR HEAL. 2021;232:.

Low SARS-CoV-2 infection rates and high vaccine-induced immunity among German healthcare workers at the end of the third wave of the COVID-19 pandemic
Brehm T, Thompson M, Ullrich F, Schwinge D, Addo M, Spier A, Knobloch J, Aepfelbacher M, Lohse A, Lütgehetmann M, Schulze Zur Wiesch J
INT J HYG ENVIR HEAL. 2021;238:.

Nanoparticle-mediated targeting of autoantigen peptide to cross-presenting liver sinusoidal endothelial cells protects from CD8 T-cell-driven autoimmune cholangitis
Carambia A, Gottwick C, Schwinge D, Stein S, Digigow R, Şeleci M, Mungalpara D, Heine M, Schuran F, Corban C, Lohse A, Schramm C, Heeren J, Herkel J
IMMUNOLOGY. 2021;162(4):452-463.

Failure on voxilaprevir, velpatasvir, sofosbuvir and efficacy of rescue therapy
Dietz J, Di Maio V, de Salazar A, Merino D, Vermehren J, Paolucci S, Kremer A, Lara M, Pardo M, Zoller H, Degasperi E, Peiffer K, Sighinolfi L, Téllez F, Graf C, Ghisetti V, Schreiber J, Fernández-Fuertes E, Boglione L, Muñoz-Medina L, Stauber R, Gennari W, Figueruela B, Santos J, Lampertico P, Zeuzem S, Ceccherini-Silberstein F, García F, Sarrazin C
J HEPATOL. 2021;74(4):801-810.

Risk factors associated with bleeding after prophylactic endoscopic variceal ligation in cirrhosis
Drolz A, Schramm C, Seiz O, Groth S, Vettorazzi E, Horvatits T, Wehmeyer M, Schramm C, Goeser T, Roesch T, Lohse A, Kluwe J
ENDOSCOPY. 2021;53(3):226-234.

Performance of non-invasive fibrosis scores in non-alcoholic fatty liver disease with and without morbid obesity
Drolz A, Wolter S, Wehmeyer M, Piecha F, Horvatits T, Schulze Zur Wiesch J, Lohse A, Mann O, Kluwe J
INT J OBESITY. 2021;45(10):2197-2204.

Diagnostic and Prognostic Value of miR-16, miR-146a, miR-192 and miR-221 in Exosomes of Hepatocellular Carcinoma and Liver Cirrhosis Patients
Fründt T, Krause L, Hussey E, Steinbach B, Köhler D, von Felden J, Schulze K, Lohse A, Wege H, Schwarzenbach H
CANCERS. 2021;13(10):2484.

Update of the simplified criteria for autoimmune hepatitis: evaluation of the methodology for immunoserological testing
Galaski J, Weiler-Normann C, Schakat M, Zachou K, Muratori P, Lampalzer S, Haag F, Schramm C, Lenzi M, Dalekos G, Lohse A
J HEPATOL. 2021;74(2):312-320.

Liver transplantation for acute‐on‐chronic liver failure predicts post‐transplant mortality and impaired long‐term quality of life
Goosmann L, Buchholz A, Bangert K, Fuhrmann V, Kluge S, Lohse A, Huber S, Fischer L, Sterneck M, Hübener P
LIVER INT. 2021;41(3):574-584.

Improvement of renal function prior to liver transplantation is not associated with better long-term renal outcome or survival
Horvatits T, Hübener P, Touma M, Horvatits K, Fischer L, Lohse A, Sterneck M
ANN HEPATOL. 2021;26:.

Hepatitis E virus persists in the ejaculate of chronically infected men
Horvatits T, Wißmann J, Johne R, Groschup M, Gadicherla A, Wiesch J, Eiden M, Todt D, Reimer R, Dähnert L, Schöbel A, Horvatits K, Lübke R, Wolschke C, Ayuk F, Rybczynski M, Lohse A, Addo M, Herker E, Lütgehetmann M, Steinmann E, Pischke S
J HEPATOL. 2021;75(1):55-63.

Früherkennung von psychischer Komorbidität in der stationären dermatologischen und internistischen Versorgung: Darstellung eines neuen Versorgungskonzeptes
Kohlmann S, Köster F, Braunschneider L, Meier A, Lohse A, Schneider S, Loeper S, Löwe B
PSYCHOTHER PSYCH MED. 2021;71(9-10):406-411.

Histological activity despite normal ALT and IgG serum levels in patients with autoimmune hepatitis and cirrhosis
Laschtowitz A, Zachou K, Lygoura V, Pape S, Derben F, Jaeckel E, Oller-Moreno S, Weidemann S, Krech T, Piecha F, Schön G, Liebhoff A, Al Tarrah M, Heneghan M, Drenth J, Dalekos G, Taubert R, Lohse A, Schramm C
JHEP REP. 2021;3(4):100321.

Infektionen und Gesellschaft
Lohse A, Addo M
2021. Infektionen und Gesellschaft. Lohse A (Hrsg.). 1. Aufl. Hamburg: Springer, 3-4; 135-147.

Das Schweigen der Leber
Lohse A, Goettges U
2021. Das Schweigen der Leber. 1. Aufl. Stuttgart: Georg Thieme Verlag, 1-271.

Magen-Darm-Mittel und Lebertherapeutika
Lohse A, Huber S
2021. Arzneiverordnungs-Report 2021. Ludwig W, Mühlbauer B, Seifert R (Hrsg.). 1. Aufl. Berlin: Springer-Verlag, Berlin, 523-550.

Reply to: "Both tacrolimus and mycophenylate mophetil should be considered second-line therapy for autoimmune hepatitis"
Lohse A, Sebode M, Vesterhus M
J HEPATOL. 2021;74(3):755-756.

SARS-CoV-2 infection in patients with autoimmune hepatitis
Marjot T, Buescher G, Sebode M, Barnes E, Barritt A, Armstrong M, Baldelli L, Kennedy J, Mercer C, Ozga A, Casar C, Schramm C, Moon A, Webb G, Lohse A
J HEPATOL. 2021;74(6):1335-1343.

SARS-CoV-2 vaccination in patients with liver disease: responding to the next big question
Marjot T, Webb G, Barritt A, Ginès P, Lohse A, Moon A, Pose E, Trivedi P, Barnes E
LANCET GASTROENTEROL. 2021;6(3):156-158.

TIPS and splenorenal shunt for complications of portal hypertension in chronic hepatosplenic schistosomiasis-A case series and review of the literature
Nordmann T, Schlabe S, Feldt T, Gobbi F, Krieg A, Bode J, Fuchs A, Kraef C, Praktiknjo M, Trebicka J, Ramharter M, Addo M, Strassburg C, Lohse A, Luedde T, Schmiedel S, Orth H
PLOS NEGLECT TROP D. 2021;15(12):.

Bilateral Hematothorax without Hematemesis - an unusual Presentation of Variceal Bleeding
Paparoupa M, Schrader J, Jung C, Boenisch O, Lohse A, Kluge S
HEPATOLOGY. 2021;73(3):1233-1235.

Evolution of liver stiffness and post-treatment surveillance by liver elastography for HCV patients in the DAA era
Piecha F, Gänßler J, Ozga A, Wehmeyer M, Kluwe J, Lampalzer S, Creutzfeldt A, Buescher G, Horvatits T, Sterneck M, Pischke S, Lohse A, Schulze Zur Wiesch J
SCAND J GASTROENTERO. 2021;56(7):840-848.

Single-cell atlas of hepatic T cells reveals expansion of liver-resident naive-like CD4+ T cells in primary sclerosing cholangitis
Poch T, Krause J, Casar C, Liwinski T, Glau L, Kaufmann M, Ahrenstorf A, Hess L, Ziegler A, Martrus G, Lunemann S, Sebode M, Li J, Schwinge D, Krebs C, Franke A, Friese M, Oldhafer K, Fischer L, Altfeld M, Lohse A, Huber S, Tolosa E, Gagliani N, Schramm C
J HEPATOL. 2021;75(2):414-423.

Failure of thymic deletion and instability of autoreactive Tregs drive autoimmunity in immune-privileged liver
Preti M, Schlott L, Lübbering D, Krzikalla D, Müller A, Schuran F, Poch T, Schakat M, Weidemann S, Lohse A, Weiler-Normann C, Sebode M, Schwinge D, Schramm C, Carambia A, Herkel J
JCI INSIGHT. 2021;6(6):141462.

Cardiovascular magnetic resonance demonstrates structural cardiac changes following transjugular intrahepatic portosystemic shunt
Radunski U, Kluwe J, Klein M, Galante A, Lund G, Sinning C, Bohnen S, Tahir E, Starekova J, Bannas P, Stehning C, Adam G, Lohse A, Blankenberg S, Muellerleile K, Benten D
SCI REP-UK. 2021;11(1):.

Drug-induced liver injury at a tertiary care centre in Germany: Model for End-stage Liver Disease is the best predictor of outcome
Reike-Kunze M, Zenouzi R, Hartl J, Krech T, Weidemann S, Sterneck M, Weiler-Normann C, Lohse A, Schramm C, Sebode M
LIVER INT. 2021;41(10):2383-2395.

Clinical and Radiological Characterization of Patients with Immobilizing and Progressive Stress Fractures in Methotrexate Osteopathy
Rolvien T, Jandl N, Stürznickel J, Beil F, Kötter I, Oheim R, Lohse A, Barvencik F, Amling M
CALCIFIED TISSUE INT. 2021;108(2):219-230.

Mobile app requirements for patients with rare liver diseases: A single center survey for the ERN RARE-LIVER‬‬‬
Rüther D, Sebode M, Lohse A, Wernicke S, Böttinger E, Casar C, Braun F, Schramm C
CLIN RES HEPATOL GAS. 2021;45(6):.

Bone microarchitecture in patients with autoimmune hepatitis
Schmidt C, Stürznickel J, Strahl A, Oheim R, Weiler-Normann C, Sebode M, Barvencik F, Lohse A, Schinke T, Amling M, Schramm C, Rolvien T
J BONE MINER RES. 2021;36(7):1316-1325.

Next-generation immunosequencing reveals pathological T cell architecture in autoimmune hepatitis
Schultheiß C, Germany D, Willscher E, Oberle A, Fanchi L, Bonzanni N, Wildner N, Schulze-Zur-Wiesch J, Weiler-Normann C, Lohse A, Binder M
HEPATOLOGY. 2021;73(4):1436-1448.

Early Detection of Hepatocellular Carcinoma Since the Introduction of the German Clinical Practice Guideline in 2013
Schulze K, Felden J, Fründt T, Krause J, Werner T, Casar C, Jung C, Ittrich H, Sterneck M, Li J, Heumann A, Fischer L, Adam G, Lohse A, Wege H
DTSCH ARZTEBL INT. 2021;118(31-32):540-541.

Europäisches Referenznetzwerk für seltene Lebererkrankungen (ERN RARE-LIVER)
Schulz L, Sebode M, Schramm C, Lohse A
INTERNIST. 2021;62(4):441-448.

A Randomized Trial of a Transglutaminase 2 Inhibitor for Celiac Disease
Schuppan D, Mäki M, Lundin K, Isola J, Friesing-Sosnik T, Taavela J, Popp A, Koskenpato J, Langhorst J, Hovde Ø, Lähdeaho M, Fusco S, Schumann M, Török H, Kupcinskas J, Zopf Y, Lohse A, Scheinin M, Kull K, Biedermann L, Byrnes V, Stallmach A, Jahnsen J, Zeitz J, Mohrbacher R, Greinwald R
NEW ENGL J MED. 2021;385(1):35-45.

Aryl Hydrocarbon Receptor Activity in Hepatocytes Sensitizes to Hyperacute Acetaminophen-Induced Hepatotoxicity in Mice
Schuran F, Lommetz C, Steudter A, Ghallab A, Wieschendorf B, Schwinge D, Zuehlke S, Reinders J, Heeren J, Lohse A, Schramm C, Herkel J, Carambia A
CELL MOL GASTROENTER. 2021;11(2):371-388.

Leukocyte-Derived High-Mobility Group Box 1 Governs Hepatic Immune Responses to Listeria monocytogenes
Volmari A, Foelsch K, Zierz E, Yan K, Qi M, Bartels K, Kondratowicz S, Boettcher M, Reimers D, Nishibori M, Liu K, Schwabe R, Lohse A, Huber S, Mittruecker H, Hübener P
HEPATOL COMMUN. 2021;5(12):2104-2120.

Milde COVID-19-Verläufe bei Mitarbeitenden einer Universitätsklinik: Die „erste Welle“ am Universitätsklinikum Hamburg-Eppendorf
von Felden J, Brehm T, Schulze-Zur-Wiesch J, Addo M, Lohse A, Knobloch J, Koch T
BUNDESGESUNDHEITSBLA. 2021;64(9):1165-1168.

Sequential Systemic Treatment in Advanced Hepatocellular Carcinoma Is Able to Prolong Median Survival to More than 3 Years in a Selected Real-World Cohort
von Felden J, Karkmann K, Ittrich H, Gil-Ibanez I, Fründt T, Krause J, Lohse A, Wege H, Schulze K
VISC MED. 2021;37(2):87-93.

Autoimmune hepatitis: from immunopathogenesis to diagnostic and therapeutic innovation
Weiler-Normann C, Lohse A
CURR OPIN GASTROEN. 2021;37(2):86-90.

Prevalence of COVID-19 in patients with autoimmune liver disease in Europe: A patient-oriented online survey
Zecher B, Buescher G, Willemse J, Walmsley M, Taylor A, Leburgue A, Schramm C, Lohse A, Sebode M
UNITED EUR GASTROENT. 2021;9(7):797-808.

Schwere sekundär sklerosierende Cholangitis als Manifestation einer sehr seltenen Grunderkrankung
Zecher B, Zenouzi R, Lang M, Karagiannis P, Clauditz T, Fischer L, Sterneck M, Schramm C, Lohse A, Sebode M
INTERNIST. 2021;62(12):1349-1353.

Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients
Zhao Y, Kilian C, Turner J, Bosurgi L, Roedl K, Bartsch P, Gnirck A, Cortesi F, Schultheiß C, Hellmig M, Enk L, Hausmann F, Borchers A, Wong M, Paust H, Siracusa F, Scheibel N, Herrmann M, Rosati E, Bacher P, Kylies D, Jarczak D, Lütgehetmann M, Pfefferle S, Steurer S, Zur Wiesch J, Puelles V, Sperhake J, Addo M, Lohse A, Binder M, Huber S, Huber T, Kluge S, Bonn S, Panzer U, Gagliani N, Krebs C
SCI IMMUNOL. 2021;6(56):.

High rates of cirrhosis and severe clinical events in patients with HBV/HDV co-infection:longitudinal analysis of a German cohort:longitudinal analysis of a German cohort
Bockmann J, Grube M, Hamed V, von Felden J, Landahl J, Wehmeyer M, Giersch K, Hall M, Murray J, Dandri M, Lüth S, Lohse A, Lütgehetmann M, Schulze Zur Wiesch J
BMC GASTROENTEROL. 2020;20(1):24.

Risk factors for different intestinal pathogens among patients with traveler's diarrhea: A retrospective analysis at a German travel clinic (2009-2017)
Brehm T, Lütgehetmann M, Tannich E, Addo M, Lohse A, Rolling T, Vinnemeier C
TRAVEL MED INFECT DI. 2020;37:101706.

High effectiveness of multimodal infection control interventions in preventing SARS−CoV−2 infections in healthcare professionals: a prospective longitudinal seroconversion study
Brehm T, Schwinge D, Lampalzer S, Schlicker V, Küchen J, Thompson M, Ullrich F, Huber S, Schmiedel S, Addo M, Lütgehetmann M, Knobloch J, Schulze zur Wiesch J, Lohse A
medRxiv BMJ. 2020.

Sofosbuvir monotherapy fails to achieve HEV RNA elimination in patients with chronic hepatitis E - The HepNet SofE pilot study
Cornberg M, Pischke S, Müller T, Behrendt P, Piecha F, Benckert J, Todt D, Steinmann E, Papkalla A, von Karpowitz M, Koch A, Lohse A, Hardtke S, Manns M, Wedemeyer H
J HEPATOL. 2020;73(3):696-699.

Long-term outcome in PSC patients receiving azathioprine: Does immunosuppression have a positive effect on survival?
Creutzfeldt A, Piecha F, Schattenberg J, Schramm C, Lohse A
J HEPATOL. 2020;73(5):1285-1287.

Characterization of the immune cell landscape of patients with NAFLD
Diedrich T, Kummer S, Galante A, Drolz A, Schlicker V, Lohse A, Kluwe J, Eberhard J, Schulze Zur Wiesch J
PLOS ONE. 2020;15(3):e0230307.

Autoantibodies to intracellular "rods and rings" structures in two patients with autoimmune hepatitis treated with azathioprine
Galaski J, Koop A, Lütgehetmann M, Lohse A, Weiler-Normann C
AUTOIMMUNITY. 2020;53(6):362-365.

Features and outcome of AIH patients without elevation of IgG
Hartl J, Miquel R, Zachou K, Wong G, Asghar A, Pape S, Sebode M, Peiseler M, Zenouzi R, Ehlken H, Krech T, Weiler-Normann C, Drenth J, Oo Y, Dalekos G, Heneghan M, Schramm C, Lohse A
JHEP REP. 2020;2(3):100094.

Long-term survival after liver transplantation for autoimmune hepatitis - results from the European Liver Transplant Registry
Heinemann M, Adam R, Berenguer M, Mirza D, Malek-Hosseini S, O'Grady J, Lodge P, Pratschke J, Boudjema K, Paul A, Zieniewicz K, Fronek J, Weiss K, Karam V, Duvoux C, Lohse A, Schramm C
LIVER TRANSPLANT. 2020;26(7):866-877.

Autoimmune hepatitis: Possible triggers, potential treatments
Herkel J, Carambia A, Lohse A
J HEPATOL. 2020;73(2):446-448.

Analysis of Co-inhibitory Receptor Expression in COVID-19 Infection Compared to Acute Plasmodium falciparum Malaria: LAG-3 and TIM-3 Correlate With T Cell Activation and Course of Disease
Herrmann M, Schulte S, Wildner N, Wittner M, Brehm T, Ramharter M, Woost R, Lohse A, Jacobs T, Schulze zur Wiesch J
FRONT IMMUNOL. 2020;11:1870.

Significance of Anti-Nuclear Antibodies and Cryoglobulins in Patients with Acute and Chronic HEV Infection
Horvatits T, Schulze Zur Wiesch J, Polywka S, Buescher G, Lütgehetmann M, Hussey E, Horvatits K, Peine S, Haag F, Addo M, Lohse A, Weiler-Normann C, Pischke S
PATHOGENS. 2020;9(9):.

No link between male infertility and HEV genotype 3 infection
Horvatits T, Varwig-Janssen D, Schulze Zur Wiesch J, Lübke R, Reucher S, Frerk S, Addo M, Schneider S, Lohse A, Luetgehetmann M, Pischke S
GUT. 2020;69(6):1150-1151.

Systemic interleukin 10 levels indicate advanced stages while interleukin 17A levels correlate with reduced survival in esophageal adenocarcinomas
Karstens K, Kempski J, Giannou A, Freiwald E, Reeh M, Tachezy M, Izbicki J, Lohse A, Gagliani N, Huber S, Pelczar P
PLOS ONE. 2020;15(4):e0231833.

Anti-inflammatory microenvironment of esophageal adenocarcinomas negatively impacts survival
Karstens K, Kempski J, Giannou A, Pelczar P, Steglich B, Steurer S, Freiwald E, Woestemeier A, Konczalla L, Tachezy M, Reeh M, Bockhorn M, Perez D, Mann O, Lohse A, Roesch T, Izbicki J, Gagliani N, Huber S
CANCER IMMUNOL IMMUN. 2020;69(6):1043-1056.

IL22BP Mediates the Anti-Tumor Effects of Lymphotoxin Against Colorectal Tumors in Mice and Humans
Kempski J, Giannou A, Riecken K, Zhao L, Steglich B, Lücke J, Garcia-Perez L, Karstens K, Wöstemeier A, Nawrocki M, Pelczar P, Witkowski M, Nilsson S, Konczalla L, Shiri A, Kempska J, Wahib R, Brockmann L, Huber P, Gnirck A, Turner J, Zazara D, Arck P, Stein A, Simon R, Daubmann A, Meiners J, Perez D, Strowig T, Koni P, Kruglov A, Sauter G, Izbicki J, Guse A, Roesch T, Lohse A, Flavell R, Gagliani N, Huber S
GASTROENTEROLOGY. 2020;159(4):1417-1430.e3.

Safety and immunogenicity of a modified vaccinia virus Ankara vector vaccine candidate for Middle East respiratory syndrome: an open-label, phase 1 trial
Koch T, Dahlke C, Fathi A, Kupke A, Krähling V, Okba N, Halwe S, Rohde C, Eickmann M, Volz A, Hesterkamp T, Jambrecina A, Borregaard S, Ly M, Zinser M, Bartels E, Poetsch J, Neumann R, Fux R, Schmiedel S, Lohse A, Haagmans B, Sutter G, Becker S, Addo M
LANCET INFECT DIS. 2020;20(7):827-838.

Therapeutic Targeting of Myeloperoxidase Attenuates NASH in Mice
Koop A, Thiele N, Steins D, Michaëlsson E, Wehmeyer M, Scheja L, Steglich B, Huber S, Schulze zur Wiesch J, Lohse A, Heeren J, Kluwe J
HEPATOL COMMUN. 2020;4(10):1441-1458.

Hepatocellular carcinoma: Intratumoral EpCAM-positive cancer stem cell heterogeneity identifies high-risk tumor subtype
Krause J, von Felden J, Casar C, Fründt T, Galaski J, Schmidt C, Jung C, Ittrich H, Weidemann S, Krech T, Heumann A, Li J, Fischer L, Sauter G, Lohse A, Wege H, Schulze K
BMC CANCER. 2020;20(1):1130.

Monocytes as potential mediators of pathogen-induced Th17 differentiation in patients with primary sclerosing cholangitis (PSC)
Kunzmann L, Schoknecht T, Poch T, Henze L, Stein S, Kriz M, Grewe I, Preti M, Hartl J, Pannicke N, Peiseler M, Sebode M, Zenouzi R, Horvatits T, Böttcher M, Petersen B, Weiler-Normann C, Hess L, Ahrenstorf A, Lunemann S, Martrus G, Fischer L, Li J, Carambia A, Kluwe J, Huber S, Lohse A, Franke A, Herkel J, Schramm C, Schwinge D
HEPATOLOGY. 2020;72(4):1310-1326.

A disease-specific decline of the relative abundance of Bifidobacterium in patients with autoimmune hepatitis
Liwinski T, Casar C, Ruehlemann M, Bang C, Sebode M, Hohenester S, Denk G, Lieb W, Lohse A, Franke A, Schramm C
ALIMENT PHARM THER. 2020;51(12):1417-1428.

Alterations of the bile microbiome in primary sclerosing cholangitis
Liwinski T, Zenouzi R, John C, Ehlken H, Rühlemann M, Bang C, Groth S, Lieb W, Kantowski M, Andersen N, Schachschal G, Karlsen T, Hov J, Rösch T, Lohse A, Heeren J, Franke A, Schramm C
GUT. 2020;69(4):665-672.

Management of patients with autoimmune liver disease during COVID-19 pandemic
Lleo A, Invernizzi P, Lohse A, Aghemo A, Carbone M
J HEPATOL. 2020;73(2):453-455.

Second-line and third-line therapy for autoimmune hepatitis: A position statement from the European Reference Network on Hepatological Diseases and the International Autoimmune Hepatitis Group
Lohse A, Sebode M, Jørgensen M, Ytting H, Karlsen T, Kelly D, Manns M, Vesterhus M
J HEPATOL. 2020;73(6):1496-1506.

Rapid Response to Treatment of Autoimmune Hepatitis Associated With Remission at 6 and 12 Months
Pape S, Gevers T, Vrolijk J, van Hoek B, Bouma G, van Nieuwkerk C, Taubert R, Jaeckel E, Manns M, Papp M, Sipeki N, Stickel F, Efe C, Ozaslan E, Purnak T, Nevens F, Kessener D, Kahraman A, Wedemeyer H, Hartl J, Schramm C, Lohse A, Drenth J, Heneghan M
CLIN GASTROENTEROL H. 2020;18(7):1609-1617.e4.

High discontinuation rate of azathioprine in autoimmune hepatitis, independent of time of treatment initiation
Pape S, Gevers T, Vrolijk J, van Hoek B, Bouma G, van Nieuwkerk C, Taubert R, Jaeckel E, Manns M, Papp M, Sipeki N, Stickel F, Efe C, Ozaslan E, Purnak T, Nevens F, Kessener D, Kahraman A, Wedemeyer H, Hartl J, Schramm C, Lohse A, Heneghan M, Drenth J
LIVER INT. 2020;40(9):2164-2171.

Clinical evaluation of five different automated SARS-CoV-2 serology assays in a cohort of hospitalized COVID-19 patients
Pflüger L, Bannasch J, Brehm T, Pfefferle S, Hoffmann A, Nörz D, van der Meirschen M, Kluge S, Haddad M, Pischke S, Hiller J, Addo M, Lohse A, Wiesch J, Peine S, Aepfelbacher M, Lütgehetmann M
J CLIN VIROL. 2020;130:104549.

Treatment and re-treatment results of HCV patients in the DAA era
Piecha F, Gänßler J, Ozga A, Wehmeyer M, Dietz J, Kluwe J, Laschtowitz A, von Felden J, Sterneck M, Jordan S, Pischke S, Lohse A, Schulze Zur Wiesch J
PLOS ONE. 2020;15(5):e0232773.

A System to Determine Risk of Osteoporosis in Patients With Autoimmune Hepatitis
Schmidt T, Schmidt C, Strahl A, Mussawy H, Rolvien T, Jandl N, Casar C, Oheim R, Schinke T, Lohse A, Amling M, Schramm C, Barvencik F
CLIN GASTROENTEROL H. 2020;18(1):226-233.e3.

Population-based study of autoimmune hepatitis and primary biliary cholangitis in Germany: rising prevalences based on ICD codes, yet deficits in medical treatment
Sebode M, Kloppenburg A, Aigner A, Lohse A, Schramm C, Linder R
Z GASTROENTEROL. 2020;58(5):431-438.

Metamizole Has Been Overlooked as a Trigger for Acute Liver Injury and Acute Liver Failure
Sebode M, Lohse A, Schramm C
DTSCH ARZTEBL INT. 2020;117(37):610.

Metamizole: An underrated agent causing severe idiosyncratic drug-induced liver injury
Sebode M, Reike-Kunze M, Weidemann S, Zenouzi R, Hartl J, Peiseler M, Liwinski T, Schulz L, Weiler-Normann C, Sterneck M, Lohse A, Schramm C
BRIT J CLIN PHARMACO. 2020;86(7):1406-1415.

Permanent immunosuppression in SLA/LP-positive autoimmune hepatitis is required although overall response and survival are similar
Zachou K, Weiler-Normann C, Muratori L, Muratori P, Lohse A, Dalekos G
LIVER INT. 2020;40(2):368-376.

Das Europäische Referenznetzwerk für seltene Lebererkrankungen (ERN RARE-LIVER): Betroffene Patienten besser versorgen, Konsilangebot für ärztliche Kollegen
Zecher B, Sebode M, Lohse A
Z GASTROENTEROL. 2020;58(10):1006.

Sex differences in clinical presentation and prognosis in patients with primary biliary cholangitis
Abdulkarim M, Zenouzi R, Sebode M, Schulz L, Quaas A, Lohse A, Schramm C, Weiler-Normann C
SCAND J GASTROENTERO. 2019;54(11):1391-1396.

HCV-specific CD4+ T cells of patients with acute and chronic HCV infection display high expression of TIGIT and other co-inhibitory molecules
Ackermann C, Smits M, Woost R, Eberhard J, Peine S, Kummer S, Marget M, Kuntzen T, Kwok W, Lohse A, Jacobs T, Boettler T, Schulze Zur Wiesch J
SCI REP-UK. 2019;9(1):10624.

Chronic Hepatitis E is associated with cholangitis
Beer A, Holzmann H, Pischke S, Behrendt P, Wrba F, Schlue J, Drebber U, Neudert B, Halilbasic E, Kreipe H, Lohse A, Sterneck M, Wedemeyer H, Manns M, Dienes H
LIVER INT. 2019;39(10):1876-1883.

Position statement on access to care in rare liver diseases: advancements of the European reference network (ERN) RARE-LIVER
Bernts L, Jones D, Kaatee M, Lohse A, Schramm C, Sturm E, Drenth J
ORPHANET J RARE DIS. 2019;14(1):169.

TNF-Producing Th1 Cells Are Selectively Expanded in Liver Infiltrates of Patients with Autoimmune Hepatitis
Bovensiepen C, Schakat M, Sebode M, Zenouzi R, Hartl J, Peiseler M, Li J, Henze L, Woestemeier A, Schramm C, Lohse A, Herkel J, Weiler-Normann C
J IMMUNOL. 2019;203(12):3148-3156.

Lactate Improves Prediction of Short-Term Mortality in Critically Ill Patients With Cirrhosis
Drolz A, Horvatits T, Rutter K, Landahl F, Roedl K, Meersseman P, Wilmer A, Kluwe J, Lohse A, Kluge S, Trauner M, Fuhrmann V
HEPATOLOGY. 2019;69(1):258-269.

Review article: unanswered clinical and research questions in autoimmune hepatitis-conclusions of the International Autoimmune Hepatitis Group Research Workshop.
Dyson J, De Martin E, Dalekos G, Drenth J, Herkel J, Hubscher S, Kelly D, Lenzi M, Milkiewicz P, Oo Y, Heneghan M, Lohse A
ALIMENT PHARM THER. 2019;49(5):528-536.

Hepatitis delta virus persists during liver regeneration and is amplified through cell division both in vitro and in vivo
Giersch K, Bhadra O, Volz T, Allweiss L, Riecken K, Fehse B, Lohse A, Petersen J, Sureau C, Urban S, Dandri M, Lütgehetmann M
GUT. 2019;68(1):150-157.

Liver infiltrating T cells regulate bile acid metabolism in experimental cholangitis
Glaser F, John C, Engel B, Höh B, Weidemann S, Dieckhoff J, Stein S, Becker N, Casar C, Amrei Schuran F, Wieschendorf B, Preti M, Jessen F, Franke A, Carambia A, Lohse A, Ittrich H, Herkel J, Heeren J, Schramm C, Schwinge D
J HEPATOL. 2019;71(4):783-792.

Endoscopic retrograde cholangiography and percutaneous transhepatic cholangiodrainage in biliary strictures after liver transplantation: Long-term outcome predictors and influence on patient survival
Heinemann M, Tafrishi B, Pischke S, Fischer L, Rösch T, Lohse A, Sterneck M, Denzer U
LIVER INT. 2019;39(6):1155-1164.

Einsatz von Protonenpumpenhemmern bei Patienten mit Leberzirrhose – eine Umfrage unter Hepatologen in Deutschland
Horvatits T, Drolz A, Wehmeyer M, Steib C, Trebicka J, Lohse A, Kluwe J
Z GASTROENTEROL. 2019;57(6):729-733.

The Clinical Perspective on Hepatitis E
Horvatits T, Schulze Zur Wiesch J, Lütgehetmann M, Lohse A, Pischke S
VIRUSES-BASEL. 2019;11(7):.

Rate of Spleen Length Progression is a Marker of Outcome in Patients with Primary Sclerosing Cholangitis
Jung F, Cazzagon N, Vettorazzi E, Corpechot C, Chazouilleres O, Arrivé L, Lohse A, Schramm C, Ehlken H
CLIN GASTROENTEROL H. 2019;17(12):2613-2615.

Prospective comparison of diffusion-weighted MRI and dynamic Gd-EOB-DTPA-enhanced MRI for detection and staging of hepatic fibrosis in primary sclerosing cholangitis
Keller S, Sedlacik J, Schuler T, Buchert R, Avanesov M, Zenouzi R, Lohse A, Kooijman H, Fiehler J, Schramm C, Yamamura J
EUR RADIOL. 2019;29(2):818-828.

Transjugular Intrahepatic Portosystemic Shunt (TIPS) for primary and secondary prophylaxis of variceal bleeding in hepatic schistosomiasis
Kraef C, Arand J, Galaski J, Jordan S, Kluwe J, Lohse A, Addo M, Ramharter M, Schmiedel S
TRAVEL MED INFECT DI. 2019;30:130-132.

Management der saisonalen Influenza 2017/2018: Erfahrungen an einem deutschen Universitätsklinikum
Kraef C, van der Meirschen M, Wichmann D, Kutza M, Restemeyer C, Addo M, Lohse A, Schmiedel S, Kluge S, Schulze Zur Wiesch J
BUNDESGESUNDHEITSBLA. 2019;62(7):870-880.

Detection of a Broad Range of Low-Level Major Histocompatibility Complex Class II-Restricted, Hepatitis Delta Virus (HDV)-Specific T-Cell Responses Regardless of Clinical Status
Landahl J, Bockmann J, Scheurich C, Ackermann C, Matzat V, Heide J, Nuurei T, D'Antonio G, von Felden J, Sette A, Peine S, Lohse A, Lütgehetmann M, Marget M, Sidney J, Schulze Zur Wiesch J
J INFECT DIS. 2019;219(4):568-577.

Infektionsausbrüche: Grenzen und Defizite im Risikomanagement: Kommentar zu: Ammon, A: Rapid Risk Assessments für akute Infektionsereignisse: Methoden und praktische Anwendung
Lohse A
2019. Rationale Entscheidungen unter Unsicherheit. Fleischer B, Lauterbach R, Pawlik K (Hrsg.). 1. Aufl. Berlin: Walter de Gruyter GmbH, Berlin/Boston, 54-58.

Unbestechlicher Streiter für die akademische Medizin: die nationale und internationale Gastroenterologie und Hepatologie trauert um Karl-Hermann Meyer zum Büschenfelde
Manns M, Lohse A
Z GASTROENTEROL. 2019;2019(11):1418-1419.

Initial therapy affects duration of diarrhoea in critically ill patients with Clostridioides difficile infection (CDI)
Manthey C, Dranova D, Christner M, Drolz A, Kluge S, Lohse A, Fuhrmann V
CRIT CARE. 2019;23(1):399.

Predniso(lo)ne Dosage and Chance of Remission in Patients With Autoimmune Hepatitis
Pape S, Gevers T, Belias M, Mustafajev I, Vrolijk J, van Hoek B, Bouma G, van Nieuwkerk C, Hartl J, Schramm C, Lohse A, Taubert R, Jaeckel E, Manns M, Papp M, Stickel F, Heneghan M, Drenth J
CLIN GASTROENTEROL H. 2019;17(10):2068-2075.e2.

Transjugular Intrahepatic Portosystemic Shunt: A Possible Risk Factor for Direct-Acting Antiviral Treatment Failure in Patients With Hepatitis C?
Piecha F, Gänßler J, Jordan S, Ergen C, Ittrich H, Kluwe J, Pischke S, Lohse A, Schulze Zur Wiesch J
HEPATOL COMMUN. 2019;3(5):614-619.

Ascites control by TIPS is more successful in patients with a lower paracentesis frequency and is associated with improved survival
Piecha F, Radunski U, Ozga A, Steins D, Drolz A, Horvatits T, Spink C, Ittrich H, Benten D, Lohse A, Sinning C, Kluwe J
JHEP REP. 2019;1(2):90-98.

Chronic Hepatitis E in Rheumatology and Internal Medicine Patients: A Retrospective Multicenter European Cohort Study
Pischke S, Peron J, von Wulffen M, von Felden J, Höner Zu Siederdissen C, Fournier S, Lütgehetmann M, Iking-Konert C, Bettinger D, Par G, Thimme R, Cantagrel A, Lohse A, Wedemeyer H, de Man R, Mallet V
VIRUSES-BASEL. 2019;11(2):.

Detectable Vesicular Stomatitis Virus (VSV)-Specific Humoral and Cellular Immune Responses Following VSV-Ebola Virus Vaccination in Humans
Poetsch J, Dahlke C, Zinser M, Kasonta R, Lunemann S, Rechtien A, Ly M, Stubbe H, Krähling V, Biedenkopf N, Eickmann M, Fehling S, Olearo F, Strecker T, Sharma P, Lang K, Lohse A, Schmiedel S, Becker S, Addo M
J INFECT DIS. 2019;219(4):556-561.

Pancreatitis due to pancreatic metastases of small bowel and lung neuroendocrine tumors
Reher D, Henes F, Clauditz T, Klutmann S, Izbicki J, Lohse A, Perez D, Schrader J
2019. ENETS Conference Programm. 73.

Response of the primary tumor in patients with pNETs treated with streptozotocin / 5-FU – a preliminary retrospective study
Reher D, Henes F, Gress T, Lohse A, Hörsch D, Cremer B, Rinke A, Schrader J
2019. 16th Annual ENETS Conference . 68.

Stress fractures in systemic lupus erythematosus after long-term MTX use successfully treated by MTX discontinuation and individualized bone-specific therapy
Rolvien T, Creutzfeldt A, Lohse A, Amling M
LUPUS. 2019;28(6):790-793.

Consistent alterations in faecal microbiomes of patients with primary sclerosing cholangitis independent of associated colitis
Rühlemann M, Liwinski T, Heinsen F, Bang C, Zenouzi R, Kummen M, Thingholm L, Tempel M, Lieb W, Karlsen T, Lohse A, Hov J, Denk G, Lammert F, Krawczyk M, Schramm C, Franke A
ALIMENT PHARM THER. 2019;50(5):580-589.

Immediate versus deferred antiretroviral therapy in HIV-infected patients presenting with acute AIDS-defining events (toxoplasmosis, Pneumocystis jirovecii-pneumonia): a prospective, randomized, open-label multicenter study (IDEAL-study)
Schäfer G, Hoffmann C, Arasteh K, Schürmann D, Stephan C, Jensen B, Stoll M, Bogner J, Faetkenheuer G, Rockstroh J, Klinker H, Härter G, Stöhr A, Degen O, Bibiza-Freiwald E, Hüfner A, Jordan S, Schulze Zur Wiesch J, Addo M, Lohse A, van Lunzen J, Schmiedel S
AIDS RES THER. 2019;16(1):34.

Th17 cell frequency is associated with low bone mass in primary sclerosing cholangitis
Schmidt T, Schwinge D, Rolvien T, Jeschke A, Schmidt C, Neven M, Butscheidt S, Kriz M, Kunzmann L, Mussawy H, Hubert J, Hawellek T, Rüther W, Oheim R, Barvencik F, Lohse A, Schramm C, Schinke T, Amling M
J HEPATOL. 2019;70(5):941-953.

Extended cycle streptozotocin/5-FU chemotherapy for maintenance therapy in pancreatic neuroendocrine tumors
Schrader J, Henes F, Blaeker M, Zimmermann-Fraedrich K, Pace A, Perez D, Izbicki J, Lohse A, Benten D
ENDOCRINE. 2019;65(2):460-467.

Autoimmune hepatitis: Is the autoimmunity in the family?
Sebode M, Lohse A
LIVER INT. 2019;39(1):42-44.

Inflammatory Phenotype of Intrahepatic Sulfatide-Reactive Type II NKT Cells in Humans With Autoimmune Hepatitis
Sebode M, Wigger J, Filpe P, Fischer L, Weidemann S, Krech T, Weiler-Normann C, Peiseler M, Hartl J, Tolosa E, Herkel J, Schramm C, Lohse A, Arrenberg P
FRONT IMMUNOL. 2019;10:1065.

High-Throughput Immunogenetics Reveals a Lack of Physiological T Cell Clusters in Patients With Autoimmune Cytopenias
Simnica D, Schliffke S, Schultheiß C, Bonzanni N, Fanchi L, Akyüz N, Gösch B, Casar C, Thiele B, Schlüter J, Lohse A, Binder M
FRONT IMMUNOL. 2019;10:1897.

The burden of hepatitis E among patients with haematological malignancies: A retrospective European cohort study
von Felden J, Alric L, Pischke S, Aitken C, Schlabe S, Spengler U, Giordani M, Schnitzler P, Bettinger D, Thimme R, Xhaard A, Binder M, Ayuk F, Lohse A, Cornelissen J, de Man R, Mallet V
J HEPATOL. 2019;71(3):465-472.

Proliferation of primary human hepatocytes and prevention of hepatitis B virus reinfection efficiently deplete nuclear cccDNA in vivo
Allweiss L, Volz T, Giersch K, Kah J, Raffa G, Petersen J, Lohse A, Beninati C, Pollicino T, Urban S, Lütgehetmann M, Dandri M
GUT. 2018;67(3):542-552.

Establishment of the First Well-differentiated Human Pancreatic Neuroendocrine Tumor Model
Benten D, Behrang Y, Unrau L, Weissmann V, Wolters-Eisfeld G, Burdak-Rothkamm S, Stahl F, Anlauf M, Grabowski P, Möbs M, Dieckhoff J, Sipos B, Fahl M, Eggers C, Perez D, Bockhorn M, Izbicki J, Lohse A, Schrader J
MOL CANCER RES. 2018;16(3):496-507.

Epidemiology, clinical and laboratory features of 24 consecutive cases of leptospirosis at a German infectious disease center.
Brehm T, Schulze zur Wiesch J, Lütgehetmann M, Tappe D, Eisermann P, Lohse A, Addo M, Schmiedel S
INFECTION. 2018;46(6):847-853.

Molecular and functional heterogeneity of IL-10-producing CD4+ T cells
Brockmann L, Soukou S, Steglich B, Czarnewski P, Zhao L, Wende S, Bedke T, Ergen C, Manthey C, Agalioti T, Geffken M, Seiz O, Parigi S, Sorini C, Geginat J, Fujio K, Jacobs T, Roesch T, Izbicki J, Lohse A, Flavell R, Krebs C, Gustafsson J, Antonson P, Roncarolo M, Villablanca E, Gagliani N, Huber S
NAT COMMUN. 2018;9(1):5457.

Patterns of Resistance-Associated Substitutions in Patients With Chronic HCV Infection Following Treatment With Direct-Acting Antivirals
Dietz J, Susser S, Vermehren J, Peiffer K, Grammatikos G, Berger A, Ferenci P, Buti M, Müllhaupt B, Hunyady B, Hinrichsen H, Mauss S, Petersen J, Buggisch P, Felten G, Hüppe D, Knecht G, Lutz T, Schott E, Berg C, Spengler U, von Hahn T, Berg T, Zeuzem S, Sarrazin C
GASTROENTEROLOGY. 2018;154(4):976-988.e4.

Primary sclerosing cholangitis
Dyson J, Beuers U, Jones D, Lohse A, Hudson M
LANCET. 2018;391(10139):2547-2559.

Inequity of care provision and outcome disparity in autoimmune hepatitis in the United Kingdom
Dyson J, Wong L, Bigirumurame T, Hirschfield G, Kendrick S, Oo Y, Lohse A, Heneghan M, Jones D
ALIMENT PHARM THER. 2018;48(9):951-960.

Dynamic changes of circulating miRNAs induced by the Ebola virus vaccine VSV-EBOV
Fischer T, Spohn M, Olearo F, Zinser M, Kasonta R, Stubbe H, Rechtien A, Ly M, Schmiedel S, Lohse A, Grundhoff A, Addo M, Dahlke C
VACCINE. 2018;36(46):7083-7094.

HbA1c-basiertes Screening zur Erfassung eines unerkannten Diabetes mellitus bei gastroenterologischen Patienten in einer Klinik der Maximalversorgung
Fründt T, Schröder N, Pinnschmidt H, Hölzemer A, Heer J, Lohse A, Schrader J
Z GASTROENTEROL. 2018;56(08):e388-e389.

Discordance in steatosis classification between liver biopsy and transient elastography for high controlled attenuation parameter (CAP) values
Galaski J, Schulz L, Krause J, Lohse A
Z GASTROENTEROL. 2018;56(1):36-42.

Usefulness of biochemical remission and transient elastography in monitoring disease course in autoimmune hepatitis
Hartl J, Ehlken H, Sebode M, Peiseler M, Krech T, Zenouzi R, von Felden J, Weiler-Normann C, Schramm C, Lohse A
J HEPATOL. 2018;68(4):754-763.

Response for letter "Be cautious in comparing the seroprevalence of hepatitis E detected at different years in different countries"
Horvatits T, Ozga A, Lohse A, Dalton H, Pischke S
LIVER INT. 2018;38(12):2341.

Hepatitis E seroprevalence in the Americas: A systematic review and meta-analysis
Horvatits T, Ozga A, Westhölter D, Hartl J, Manthey C, Lütgehetmann M, Rauch G, Kriston L, Lohse A, Bendall R, Wedemeyer H, Dalton H, Pischke S
LIVER INT. 2018;38(11):1951-1964.

Outcome and natural course of renal dysfunction in liver transplant recipients with severely impaired kidney function prior to transplantation
Horvatits T, Pischke S, Proske V, Fischer L, Scheidat S, Thaiss F, Fuhrmann V, Lohse A, Nashan B, Sterneck M
UNITED EUR GASTROENT. 2018;6(1):104-111.

Lack of evidence for human serum albumin as major source of HEV infections
Horvatits T, Westhölter D, Peine S, Schulze Zur Wiesch J, Lohse A, Lütgehetmann M, Pischke S
TRANSFUSION MED. 2018;28(6):470-471.

Stabilisation of acute-on-chronic liver failure patients before liver transplantation predicts post-transplant survival
Hübener P, Sterneck M, Bangert K, Drolz A, Lohse A, Kluge S, Fischer L, Fuhrmann V
ALIMENT PHARM THER. 2018;47(11):1502-1510.

Access to care in rare liver diseases: New challenges and new opportunities
Jones D, Sturm E, Lohse A
J HEPATOL. 2018;68(3):577-585.

Association of gadolinium-enhanced magnetic resonance imaging with hepatic fibrosis and inflammation in primary sclerosing cholangitis.
Keller S, Aigner A, Zenouzi R, Kim A, Meijer A, Weidemann S, Krech T, Lohse A, Adam G, Schramm C, Yamamura J
PLOS ONE. 2018;13(3):e0193929.

Course of HEV viremia and anti-HEV IgM/IgG response in asymptomatic blood donors
Kraef C, Schlein C, Hiller J, Westhölter D, Denzer U, Horvatits T, Peine S, Lohse A, Lütgehetmann M, Polywka S, Pischke S
J CLIN VIROL. 2018;105:26-30.

GASL 2018
Lohse A
Z GASTROENTEROL. 2018;56(1):28.

Stool cultures at the ICU: get rid of it!
Manthey C, Dranova D, Christner M, Berneking L, Kluge S, Lohse A, Fuhrmann V
ANN INTENSIVE CARE. 2018;8(1):10.

Gastrointestinale Infektionen – Aktuelles
Manthey C, Lohse A, Stallmach A
Gastroenterologie up2date. 2018;14:1–17.

Fast and facile analysis of glycosylation and phosphorylation of fibrinogen from human plasma-correlation with liver cancer and liver cirrhosis
Nagel T, Klaus F, Ibanez I, Wege H, Lohse A, Meyer B
ANAL BIOANAL CHEM. 2018;410(30):7965-7977.

Efficacy and Limitations of Budesonide as a Second-line Treatment for Patients With Autoimmune Hepatitis
Peiseler M, Liebscher T, Sebode M, Zenouzi R, Hartl J, Ehlken H, Pannicke N, Weiler-Normann C, Lohse A, Schramm C
CLIN GASTROENTEROL H. 2018;16(2):260-267.e1.

Risk of endoscopic biliary interventions in primary sclerosing cholangitis is similar between patients with and without cirrhosis
Peiseler M, Reiners D, Pinnschmidt H, Sebode M, Jung F, Hartl J, Zenouzi R, Ehlken H, Groth S, Schachschal G, Rösch T, Weiler-Normann C, Lohse A, Schramm C
PLOS ONE. 2018;13(8):.

Persistierender Aszites nach TIPS-Implantation ist prädiktiv für ein geringeres transplantationsfreies Überleben bei Patienten mit Leberzirrhose
Piecha F, Steins D, Drolz A, Wehmeyer M, Horvatits T, Spink C, Ittrich H, Lohse A, Kluwe J
2018. Abstractband GASL 2018. 2018. Aufl. Thieme Deutschlnad, .

Immunosuppression as effective therapy for eosinophilic cholangiopathy: A case series and review of the literature
Reher D, Schramm C, Brinkert F, Weidemann S, Plauth M, Lohse A, Weiler-Normann C
GastroHep. 2018;1(1):33-44.

Immunosuppression as efficient therapy for Eosinophilic Cholangitis: A case series and review of the literature
Reher D, Schramm C, Brinkert F, Weidemann S, Plauth M, Lohse A, Weiler-Normann C
2018. Zeitschrift für Gastroenterologie. 01. Aufl. Georg Thieme Verlag KG, E2-E89.

Autoimmune Hepatitis
Sanyal A, Boyer T, Lindor K, Terrault N, Lohse A, Weiler-Normann C
2018. Zakim and Boyer's Hepatology. 7. Aufl. Philadelphia: Elsevier, .

Disease duration and stage influence bone microstructure in patients with primary biliary cholangitis
Schmidt T, Schmidt C, Schmidt F, Butscheidt S, Mussawy H, Hubert J, Hawellek T, Oehler N, Barvencik F, Lohse A, Schinke T, Schramm C, Amling M, Rolvien T
J BONE MINER RES. 2018;33(6):1011-1019.

Variant syndromes of primary biliary cholangitis
Schulz L, Sebode M, Weidemann S, Lohse A
BEST PRACT RES CL GA. 2018;34-35:55-61.

Autoimmune hepatitis: From current knowledge and clinical practice to future research agenda
Sebode M, Hartl J, Vergani D, Lohse A
LIVER INT. 2018;38(1):15-22.

Successful treatment of chronic hepatitis C with ground ledipasvir/sofosbuvir in a patient with Crohn's disease and short bowel syndrome
von Felden J, Scheurich C, Yamamura J, Brainard D, Mogalian E, Lohse A, Schulze Zur Wiesch J
J VIRAL HEPATITIS. 2018;25(2):214-215.

Time trend of reported cases and publications: hepatitis E in comparison to hepatitis A - D in Germany from 2001 to 2016
Wehmeyer M, Hartl J, von Wulffen M, Lohse A, Pischke S
Z GASTROENTEROL. 2018;56(1):29-35.

HEV-positive blood donations represent a relevant infection risk for immunosuppressed recipients
Westhölter D, Hiller J, Denzer U, Polywka S, Ayuk F, Rybczynski M, Horvatits T, Gundlach S, Blöcker J, Schulze Zur Wiesch J, Fischer N, Addo M, Peine S, Göke B, Lohse A, Lütgehetmann M, Pischke S
J HEPATOL. 2018;69(1):36-42.

Follow-up magnetic resonance imaging/3D-magnetic resonance cholangiopancreatography in patients with primary sclerosing cholangitis: challenging for experts to interpret
Zenouzi R, Liwinski T, Yamamura J, Weiler-Normann C, Sebode M, Keller S, Lohse A, Schramm C
ALIMENT PHARM THER. 2018;48(2):169-178.

Patients with primary biliary cholangitis and fatigue present with depressive symptoms and selected cognitive deficits, but with normal attention performance and brain structure
Zenouzi R, von der Gablentz J, Heldmann M, Göttlich M, Weiler-Normann C, Sebode M, Ehlken H, Hartl J, Fellbrich A, Siemonsen S, Schramm C, Münte T, Lohse A
PLOS ONE. 2018;13(1):e0190005.

Improved detection of alcohol consumption using the novel marker phosphatidylethanol in the transplant setting: results of a prospective study
Andresen-Streichert H, Beres Y, Weinmann W, Schröck A, Müller A, Skopp G, Pischke S, Vettorazzi E, Lohse A, Nashan B, Sterneck M
TRANSPL INT. 2017;30(6):611-620.

TLR7-mediated activation of XBP1 correlates with the IFNα production in humans
Beisel C, Ziegler S, Martrus Zapater G, Chapel A, Griesbeck M, Hildebrandt H, Lohse A, Altfeld M
CYTOKINE. 2017;94:55-58.

Dose-dependent T-cell Dynamics and Cytokine Cascade Following rVSV-ZEBOV Immunization
Dahlke C, Kasonta R, Lunemann S, Krähling V, Zinser M, Biedenkopf N, Fehling S, Ly M, Rechtien A, Stubbe H, Olearo F, Borregaard S, Jambrecina A, Stahl F, Strecker T, Eickmann M, Lütgehetmann M, Spohn M, Schmiedel S, Lohse A, Becker S, Addo M
EBIOMEDICINE. 2017;19:107-118.

Comprehensive characterization of cellular immune responses following Ebola virus infection
Dahlke C, Lunemann S, Kasonta R, Kreuels B, Schmiedel S, Ly M, Fehling S, Strecker T, Becker S, Altfeld M, Sow A, Lohse A, Muñoz-Fontela C, Addo M
J INFECT DIS. 2017;215(2):287-292.

Increased frequency of CD39+ CD56 bright Natural Killer cells in HIV-1 infection correlates with immune activation and disease progression
Dierks P, Wroblewski R, Eberhard J, Martrus G, Degen O, Hertling S, Schmiedel S, Lunemann S, Hüfner A, Lohse A, Altfeld M, van Lunzen J, Schulze Zur Wiesch J
JAIDS-J ACQ IMM DEF. 2017;74(4):467-472.

Both interferon alpha and lambda can reduce all intrahepatic HDV infection markers in HBV/HDV infected humanized mice
Giersch K, Homs M, Volz T, Helbig M, Allweiss L, Lohse A, Petersen J, Buti M, Pollicino T, Sureau C, Dandri M, Lütgehetmann M
SCI REP-UK. 2017;7(1):3757.

Activation of the Akt-CREB signalling axis by a proline-rich heptapeptide confers resistance to stress-induced cell death and inflammation
Herkel J, Schrader J, Erez N, Lohse A, Cohen I
IMMUNOLOGY. 2017;151(4):474-480.

Heme oxygenase-1 polymorphisms can affect HCV replication and treatment responses with different efficacy in humanized mice
Kah J, Volz T, Lütgehetmann M, Groth A, Lohse A, Tiegs G, Sass G, Dandri-Petersen M
LIVER INT. 2017;37(8):1128-1137.

Risk factors for excessively prolonged meropenem use in the intensive care settinga case-contol study
Katchanov J, Kreuels B, Maurer F, Wöstmann K, Jochum J, König C, Seoudy K, Rohde H, Lohse A, Wichmann D, Baehr M, Rothe C, Kluge S
BMC INFECT DIS. 2017;17(1):131.

A Protective Function of IL-22BP in Ischemia Reperfusion and Acetaminophen-Induced Liver Injury
Kleinschmidt D, Giannou A, McGee H, Kempski J, Steglich B, Huber F, Ernst T, Shiri A, Wegscheid C, Tasika E, Hübener P, Huber P, Bedke T, Steffens N, Agalioti T, Fuchs T, Noll J, Lotter H, Tiegs G, Lohse A, Axelrod J, Galun E, Flavell R, Gagliani N, Huber S
J IMMUNOL. 2017;199(12):4078-4090.

Expert clinical management of autoimmune hepatitis in the real world
Liberal R, de Boer Y, Andrade R, Bouma G, Dalekos G, Floreani A, Gleeson D, Hirschfield G, Invernizzi P, Lenzi M, Lohse A, Macedo G, Milkiewicz P, Terziroli B, van Hoek B, Vierling J, Heneghan M
ALIMENT PHARM THER. 2017;45(5):723-732.

Can Understanding the Pathogenesis of Autoimmune Hepatitis Lead to Rational Therapy?
Lohse A, Herkel J, Weiler-Normann C
DIGEST DIS. 2017;35(4):367-370.

Wichtige aktuelle Leitlinien - kurz erläutert
Manthey C, Stallmach A, Lohse A
2017. Gastroenterologische Infektiologie. Lübbert C, Vogelmann R (Hrsg.). 1. Aufl. Berlin: Walter de Gruyter GmbH & Co. KG, 505-514.

Potential impact of screening for fatty liver disease by transient elastography with liver stiffness and controlled attenuation parameter measurements: a pilot study
Peiseler M, Creutzfeldt A, Cassens I, Glaubke C, Kroll C, Lohse A, Weiler-Normann C
Z GASTROENTEROL. 2017;55(8):754-760.

Very Severe Secondary Sclerosing Cholangitis as a Sequela of Influenza
Pischke S, Fischer L, Lohse A
DTSCH ARZTEBL INT. 2017;114(25):429.

Hepatitis E virus infection beyond the liver?
Pischke S, Hartl J, Pas S, Lohse A, Jacobs B, van der Eijk A
J HEPATOL. 2017;66(5):1082-1095.

Factors associated with long-term survival after liver Transplantation, a retrospective cohort study
Pischke S, Lege M, von Wulffen M, Galante A, Otto B, Wehmeyer M, Herden U, Fischer L, Nashan B, Lohse A, Sterneck M
WORLD J HEPATOL. 2017;9(8):427-435.

High clinical manifestation rate in an imported outbreak of hepatitis E genotype 1 infection in a German group of travellers returning from India
Pischke S, Schulze zur Wiesch J, Lütgehetmann M, Kreuels B, Lüth S, Kapaun P, Benten D, Schmiedel S, Sterneck M, Lohse A, Polywka S
ANN HEPATOL. 2017;16(1):57-62.

Systems Vaccinology Identifies an Early Innate Immune Signature as a Correlate of Antibody Responses to the Ebola Vaccine rVSV-ZEBOV
Rechtien A, Richert L, Lorenzo H, Martrus G, Hejblum B, Dahlke C, Kasonta R, Zinser M, Stubbe H, Matschl U, Lohse A, Krähling V, Eickmann M, Becker S, Thiébaut R, Altfeld M, Addo M
CELL REP. 2017;20(9):2251-2261.

CD4+ T cells from patients with primary sclerosing cholangitis exhibit reduced apoptosis and down-regulation of proapoptotic Bim in peripheral blood
Schoknecht T, Schwinge D, Stein S, Weiler-Normann C, Sebode M, Mucha S, Otto B, Ellinghaus E, Stahl F, Franke A, Lohse A, Herkel J, Schramm C
J LEUKOCYTE BIOL. 2017;101(2):589-597.

Successful mTOR inhibitor therapy for a metastastic neuroendocrine tumour in a patient with a germline TSC2 mutation
Schrader J, Henes F, Perez D, Burdak-Rothkamm S, Stein A, Izbicki J, Lohse A
ANN ONCOL. 2017;28(4):904-905.

Dysfunction of hepatic regulatory T cells in experimental sclerosing cholangitis is related with IL-12 signaling
Schwinge D, von Haxthausen F, Quaas A, Carambia A, Otto B, Glaser F, Höh B, Thiele N, Schoknecht T, Huber S, Steffens N, Lohse A, Herkel J, Schramm C
J HEPATOL. 2017;66(4):798-805.

"Autoimmune(-Like)" Drug and Herb Induced Liver Injury: New Insights into Molecular Pathogenesis: New Insights into Molecular Pathogenesis
Sebode M, Schulz L, Lohse A
INT J MOL SCI. 2017;18(9):E1954.

Anti-TNF-α for necrotizing sarcoid granulomatosis of the liver
Sebode M, Weidemann S, Wehmeyer M, Lohse A, Schramm C
HEPATOLOGY. 2017;65(4):1410-1412.

TIMP-1 is upregulated, but not essential in hepatic fibrogenesis and carcinogenesis in mice
Thiele N, Wirth J, Steins D, Koop A, Ittrich H, Lohse A, Kluwe J
SCI REP-UK. 2017;7(1):714.

High expression of micro RNA-135A in hepatocellular carcinoma is associated with recurrence within 12 months after resection
von Felden J, Heim D, Schulze K, Krech T, Ewald F, Nashan B, Lohse A, Wege H
BMC CANCER. 2017;17(1):60.

Circulating tumor cells as liquid biomarker for high HCC recurrence risk after curative liver resection
von Felden J, Schulze K, Krech T, Ewald F, Nashan B, Pantel K, Lohse A, Riethdorf S, Wege H
ONCOTARGET. 2017;8(52):89978-89987.

Chronic pancreatitis in patients with liver cirrhosis negatively affects graft survival after liver transplantation
Wehmeyer M, Dammermann W, Seiz O, Zinser M, Galante A, Lohse A, Sterneck M, Nashan B, Herden U, Lüth S
PANCREATOLOGY. 2017;17(6):898-904.

Synergistische Therapiewirkung der Kombination des Hsp90 Inhibitor AUY922 und des PI3K Inhibitors BYL719 mit Everolimus bei neuroendokrinen Tumoren
Weißmann V, Benten D, Wolters-Eisfeld G, Perez D, Izbicki J, Lohse A, Schrader J
Z GASTROENTEROL. 2017;55(08):KV 402.

Viren überlisten: Globale Virusinfektionen werden beherrschbar - aber neue Gefahren drohen
Addo M, Lohse A
2016. Erkenntnis, Wissenschaft und Gesellschaft. Buchmüller W, Jakobeit C (Hrsg.). 1. Aufl. Springer-Verlag GmbH and Co. KG, 101-118.

Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe
Agnandji S, Huttner A, Zinser M, Njuguna P, Dahlke C, Fernandes J, Yerly S, Dayer J, Kraehling V, Kasonta R, Adegnika A, Altfeld M, Auderset F, Bache E, Biedenkopf N, Borregaard S, Brosnahan J, Burrow R, Combescure C, Desmeules J, Eickmann M, Fehling S, Finckh A, Goncalves A, Grobusch M, Hooper J, Jambrecina A, Kabwende A, Kaya G, Kimani D, Lell B, Lemaître B, Lohse A, Massinga-Loembe M, Matthey A, Mordmüller B, Nolting A, Ogwang C, Ramharter M, Schmidt-Chanasit J, Schmiedel S, Silvera P, Stahl F, Staines H, Strecker T, Stubbe H, Tsofa B, Zaki S, Fast P, Moorthy V, Kaiser L, Krishna S, Becker S, Kieny M, Bejon P, Kremsner P, Addo M, Siegrist C
NEW ENGL J MED. 2016;374(17):1647-60.

Human liver chimeric mice as a new model of chronic hepatitis E virus infection and preclinical drug evaluation
Allweiss L, Gass S, Giersch K, Groth A, Kah J, Volz T, Rapp G, Schöbel A, Lohse A, Polywka S, Pischke S, Herker E, Dandri-Petersen M, Lütgehetmann M
J HEPATOL. 2016;64(5):1033-1040.

Determinants and frequency of irritable bowel syndrome in a German sample
Althaus A, Broicher W, Wittkamp P, Andresen V, Lohse A, Löwe B
Z GASTROENTEROL. 2016;54(3):217-225.

Post-infectious irritable bowel syndrome (PI-IBS) after infection with Shiga-like toxin-producing Escherichia coli (STEC) O104:H4: A cohort study with prospective follow-up
Andresen V, Löwe B, Broicher W, Riegel B, Zimmermann-Fraedrich K, von Wulffen M, Gappmayer K, Wegscheider K, Treszl A, Rose M, Layer P, Lohse A
UNITED EUR GASTROENT. 2016;4(1):121-31.

Infections complicating severe alcoholic Hepatitis: Enterococcus species represent the most frequently identified pathogen
Beisel C, Blessin U, Schulze Zur Wiesch J, Wehmeyer M, Lohse A, Benten D, Kluwe J
SCAND J GASTROENTERO. 2016;51(7):807-13.

Two Cases of Hepatosplenic T-Cell Lymphoma in Adolescents Treated for Autoimmune Hepatitis
Brinkert F, Arrenberg P, Krech T, Grabhorn E, Lohse A, Schramm C
PEDIATRICS. 2016;138(3):e20154245.

Efficacy and safety of sofosbuvir/ledipasvir for the treatment of patients with hepatitis C virus re-infection after liver transplantation
Ciesek S, Proske V, Otto B, Pischke S, Costa R, Lütgehetmann M, Polywka S, Klempnauer J, Nashan B, Manns M, von Hahn T, Lohse A, Wedemeyer H, Mix H, Sterneck M
TRANSPL INFECT DIS. 2016;18(3):326-32.

Systemic inflammation in decompensated cirrhosis Characterization and role in acute-on-chronic liver failure
Clària J, Stauber R, Coenraad M, Moreau R, Jalan R, Pavesi M, Amorós À, Titos E, Alcaraz-Quiles J, Oettl K, Morales-Ruiz M, Angeli P, Domenicali M, Alessandria C, Gerbes A, Wendon J, Nevens F, Trebicka J, Laleman W, Saliba F, Welzel T, Albillos A, Gustot T, Benten D, Durand F, Ginès P, Bernardi M, Arroyo V
HEPATOLOGY. 2016;64(4):1249-64.

Reduced CD161(+) MAIT cell frequencies in HCV and HIV/HCV co-infection: Is the liver the heart of the matter?
Eberhard J, Kummer S, Hartjen P, Hüfner A, Diedrich T, Degen O, Lohse A, Lunzen J, Schulze Zur Wiesch J
J HEPATOL. 2016;65(6):1261-1263.

Spleen size for the prediction of clinical outcome in patients with primary sclerosing cholangitis
Ehlken H, Wroblewski R, Corpechot C, Arrivé L, Lezius S, Hartl J, Denzer U, Lohse A, Chazouilleres O, Schramm C
GUT. 2016;65(7):1230-1232.

Validation of Transient Elastography and Comparison with Spleen Length Measurement for Staging of Fibrosis and Clinical Prognosis in Primary Sclerosing Cholangitis
Ehlken H, Wroblewski R, Corpechot C, Arrivé L, Rieger T, Hartl J, Lezius S, Hübener P, Schulze K, Zenouzi R, Sebode M, Peiseler M, Denzer U, Quaas A, Weiler-Normann C, Lohse A, Chazouilleres O, Schramm C
PLOS ONE. 2016;11(10):e0164224.

Saccharomyces boulardii to Prevent Antibiotic-Associated Diarrhea: A Randomized, Double-Masked, Placebo-Controlled Trial
Ehrhardt S, Guo N, Hinz R, Schoppen S, May J, Reiser M, Schroeder M, Schmiedel S, Keuchel M, Reisinger E, Langeheinecke A, de Weerth A, Schuchmann M, Schaberg T, Ligges S, Eveslage M, Hagen R, Burchard G, Lohse A
OPEN FORUM INFECT DI. 2016;3(1):ofw011.

Fäkaler Mikrobiota-Transfer bei rezidivierenden Clostridium-difficile-Infektionen: Eine retrospektive multizentrische Beobachtungsstudie des MicroTrans-Registers
Hagel S, Fischer A, Ehlermann P, Frank T, Tueffers K, Sturm A, Link A, Demir M, Siebenhaar A, Storr M, Glueck T, Siegel E, Solbach P, Goeser F, Koelbel C, Lohse A, Luebbert C, Kandzi U, Maier M, Schuerle S, Lerch M, Tacke D, Cornely O, Stallmach A, Vehreschild M, German Clinical Microbiome Study Group (GCMSG) o
DTSCH ARZTEBL INT. 2016;113(35-36):583-9.

Transient elastography in autoimmune hepatitis: Timing determines the impact of inflammation and fibrosis
Hartl J, Denzer U, Ehlken H, Zenouzi R, Peiseler M, Sebode M, Hübener S, Pannicke N, Weiler-Normann C, Quaas A, Lohse A, Schramm C
J HEPATOL. 2016;65(4):769-75.

Hepatitis E Seroprevalence in Europe: A Meta-Analysis
Hartl J, Otto B, Madden R, Webb G, Woolson K, Kriston L, Vettorazzi E, Lohse A, Dalton H, Pischke S
VIRUSES-BASEL. 2016;8(8):E211.

Constitutive gp130 activation rapidly accelerates the transformation of human hepatocytes via an impaired oxidative stress response
Heim D, Gil-Ibanez I, Herden J, Parplys A, Borgmann K, Schmidt-Arras D, Lohse A, Rose-John S, Wege H
ONCOTARGET. 2016;7(34):55639-55648.

Efficacy of 6-Mercaptopurine as Second-Line Treatment for Patients With Autoimmune Hepatitis and Azathioprine Intolerance
Hübener S, Oo Y, Than N, Hübener P, Weiler-Normann C, Lohse A, Schramm C
CLIN GASTROENTEROL H. 2016;14(3):445-453.

Reply to: Efficacy of 6-Mercaptopurine as Second-Line Treatment for Patients With Autoimmune Hepatitis and Azathioprine Intolerance.
Hübener S, Than N, Oo Y, Lohse A, Schramm C
CLIN GASTROENTEROL H. 2016;14(7):1063-4.

Diffusion-weighted MRI for detection of hepatic osteodystrophy in primary sclerosing cholangitis a comparison study with dual-energy X-ray absorptiometry
Keller S, Ittrich H, Schramm C, Lohse A, Amling M, Adam G, Yamamura J
JPN J RADIOL. 2016;34(10):677-683.

Acute Ebola virus disease patient treatment and health-related quality of life in health care professionals: A controlled study
Lehmann M, Brünahl C, Addo M, Becker S, Schmiedel S, Lohse A, Schramm C, Löwe B
J PSYCHOSOM RES. 2016;83:69-74.

Reply to "Further considerations in autoimmune hepatitis"
Lohse A, Chazouilleres O, Dalekos G, Drenth J, Heneghan M, Hofer H, Lammert F, Lenzi M
J HEPATOL. 2016;64(6):1458-9.

The Development of Irritable Bowel Syndrome: A Prospective Community-Based Cohort Study
Löwe B, Lohse A, Andresen V, Vettorazzi E, Rose M, Broicher W
AM J GASTROENTEROL. 2016;111(9):1320-9.

Gastrointestinale Infektionen – Aktuelle Leitlinie und Empfehlungen
Manthey C, Stallmach A, Lohse A
Gastroenterologie up2date. 2016;12:39-49.

A pathogenic role for T cell-derived IL-22BP in inflammatory bowel disease
Pelczar P, Witkowski M, Perez L, Kempski J, Hammel A, Brockmann L, Kleinschmidt D, Wende S, Haueis C, Bedke T, Krasemann S, Steurer S, Booth C, Busch C, König A, Rauch U, Benten D, Izbicki J, Rösch T, Lohse A, Strowig T, Gagliani N, Flavell R, Huber S
SCIENCE. 2016;354(6310):358-362.

Blood-borne Hepatitis E Virus Transmission: A Relevant Risk for Immunosuppressed Patients
Pischke S, Hiller J, Lütgehetmann M, Polywka S, Rybczynski M, Ayuketang F, Lohse A
CLIN INFECT DIS. 2016;63(4):569-570.

Course of hepatitis C virus (HCV) RNA and HCV core antigen testing are predictors for reaching sustained virologic response in liver transplant recipients undergoing sofosbuvir treatment in a real-life setting
Pischke S, Polywka S, Proske V, Lang M, Jordan S, Nashan B, Lohse A, Sterneck M
TRANSPL INFECT DIS. 2016;18:141-145.

Surrogate endpoints for clinical trials in primary sclerosing cholangitis: Review and results from an International PSC Study Group consensus process
Ponsioen C, Chapman R, Chazouillères O, Hirschfield G, Karlsen T, Lohse A, Pinzani M, Schrumpf E, Trauner M, Gores G
HEPATOLOGY. 2016;63(4):1357-67.

Multiple Abszesse nach Südamerikakreuzfahrt
Reynolds K, Schofer N, Zengin E, Lohse A, Faiss S, Schmiedel S
INTERNIST. 2016;57(3):284-8.

Unique human immune signature of Ebola virus disease in Guinea
Ruibal P, Oestereich L, Lüdtke A, Becker-Ziaja B, Wozniak D, Kerber R, Korva M, Cabeza-Cabrerizo M, Bore J, Koundouno F, Duraffour S, Weller R, Thorenz A, Cimini E, Viola D, Agrati C, Repits J, Afrough B, Cowley L, Ngabo D, Hinzmann J, Mertens M, Vitoriano I, Logue C, Boettcher J, Pallasch E, Sachse A, Bah A, Nitzsche K, Kuisma E, Michel J, Holm T, Zekeng E, García-Dorival I, Wölfel R, Stoecker K, Fleischmann E, Strecker T, Di Caro A, Avšič-Županc T, Kurth A, Meschi S, Mély S, Newman E, Bocquin A, Kis Z, Kelterbaum A, Molkenthin P, Carletti F, Portmann J, Wolff S, Castilletti C, Schudt G, Fizet A, Ottowell L, Herker E, Jacobs T, Kretschmer B, Severi E, Ouedraogo N, Lago M, Negredo A, Franco L, Anda P, Schmiedel S, Kreuels B, Wichmann D, Addo M, Lohse A, De Clerck H, Nanclares C, Jonckheere S, Van Herp M, Sprecher A, Xiaojiang G, Carrington M, Miranda O, Castro C, Gabriel M, Drury P, Formenty P, Diallo B, Koivogui L, Magassouba N, Carroll M, Günther S, Muñoz-Fontela C
NATURE. 2016;533(7601):100-4.

Medizinische Versorgung von Flüchtlingen: Eine Fallserie des Universitätsklinikums Hamburg-Eppendorf
Sothmann P, Schmedt auf der Günne N, Addo M, Lohse A, Schmiedel S
DEUT MED WOCHENSCHR. 2016;141(1):34-37.

Medizinische Versorgung von Flüchtlingen – Eine Fallserie des Universitätsklinikums Hamburg-Eppendorf
Sothmann P, Schmedt auf der Günne N, Roggelin L, Kreuels B, Rothe C, Addo M, Lohse A, Schulze zur Wiesch J, Schmiedel S
FLUGMEDIZIN TROPENME. 2016;23(1):45-49.

Long-term follow-up of patients with difficult to treat type 1 autoimmune hepatitis on Tacrolimus therapy
Than N, Wiegard C, Weiler-Normann C, Füssel K, Mann J, Hodson J, Hirschfield G, Lohse A, Adams D, Schramm C, Oo Y
SCAND J GASTROENTERO. 2016;51(3):329-336.

Nonalcoholic fatty liver disease is associated with excessive calorie intake rather than a distinctive dietary pattern
Wehmeyer M, Zyriax B, Jagemann B, Roth E, Windler E, Schulze Zur Wiesch J, Lohse A, Kluwe J
MEDICINE. 2016;95(23):e3887.

Nonalcoholic Fatty Liver Disease in Patients with Autoimmune Hepatitis: Further Reason for Teeth GNASHing?
Weiler-Normann C, Lohse A
DIGEST DIS SCI. 2016;61(9):2462 - 64.

Variant Syndromes of Autoimmune Liver Diseases: Classification, Diagnosis and Management
Weiler-Normann C, Lohse A
DIGEST DIS. 2016;34(4):334-9.

Opposing role of tumor necrosis factor receptor 1 signaling in T cell-mediated hepatitis and bacterial infection in mice
Wroblewski R, Armaka M, Kondylis V, Pasparakis M, Walczak H, Mittrücker H, Schramm C, Lohse A, Kollias G, Ehlken H
HEPATOLOGY. 2016;64(2):508-521.

No Evidence That Azathioprine Increases Risk of Cholangiocarcinoma in Patients With Primary Sclerosing Cholangitis
Zenouzi R, Weismüller T, Jørgensen K, Bubenheim M, Lenzen H, Hübener P, Schulze K, Weiler-Normann C, Sebode M, Ehlken H, Pannicke N, Hartl J, Peiseler M, Hübener S, Karlsen T, Boberg K, Manns M, Lohse A, Schramm C
CLIN GASTROENTEROL H. 2016;14(12):1806-1812.

Efficacy and safety of faldaprevir, deleobuvir, and ribavirin in Treatment-naive patients with chronic Hepatitis C Virus infection and advanced liver fibrosis or cirrhosis.

J ANTIMICROB CHEMOTH. 2015;59(2):1282-1291.

Determination of ethyl glucuronide in hair for detection of alcohol consumption in patients after livertransplantation.
Andresen-Streichert H, von Rothkirch G, Vettorazzi E, Müller A, Lohse A, Frederking D, Seegers B, Nashan B, Sterneck M
THER DRUG MONIT. 2015;37(4):539-545.

Geschlechtsunterschiede bei Infektionserkrankungen
Beisel C, Lunzen J, Lohse A, Addo M, Altfeld M
DEUT MED WOCHENSCHR. 2015;140(18):1385-90.

Combined glucocorticoid and antiviral therapy of hepatitis B virus-related liver failure
Bockmann J, Dandri-Petersen M, Lüth S, Pannicke N, Lohse A, Dandri-Petersen M
WORLD J GASTROENTERO. 2015;21(7):2214-9.

Nanoparticle-based autoantigen delivery to Treg-inducing liver sinusoidal endothelial cells enables control of autoimmunity in mice
Carambia A, Freund B, Schwinge D, Bruns O, Salmen S, Ittrich H, Reimer R, Heine M, Huber S, Waurisch C, Eychmüller A, Wraith D, Korn T, Nielsen P, Weller H, Schramm C, Lüth S, Lohse A, Heeren J, Herkel J
J HEPATOL. 2015;62(6):1349-1356.

Unmet clinical need in autoimmune liver diseases
Dyson J, Webb G, Hirschfield G, Lohse A, Beuers U, Lindor K, Jones D
J HEPATOL. 2015;62(1):208-18.

Relevance of chronic hepatitis E in liver transplant recipients: a real-life setting
Galante A, Pischke S, Polywka S, Lütgehetmann M, Suneetha P, Gisa A, Hiller J, Dienes H, Nashan B, Lohse A, Sterneck M
TRANSPL INFECT DIS. 2015;17(4):617-22.

Hepatitis Delta co-infection in humanized mice leads to pronounced induction of innate immune responses in comparison to HBV mono-infection
Giersch K, Allweiss L, Volz T, Helbig M, Bierwolf J, Lohse A, Pollok J, Petersen J, Dandri-Petersen M, Lütgehetmann M
J HEPATOL. 2015;63(2):346-53.

Ökonomische Auswirkungen einer Clostridium-difficile-Enterokoloitis in deutschen Krankenhäusern auf der Basis von DRG-Kostendaten
Grube R, Heinlein W, Scheffer H, Rathmayer M, Schepp W, Lohse A
Z GASTROENTEROL. 2015;53(5):391-397.

S2k-Leitlinie Gastrointestinale Infektionen und Morbus Whipple
Hagel S, Epple H, Feurle G, Kern W, Lynen-Jansen P, Malfertheiner P, Marth T, Meyer E, Mielke M, Moos V, von Müller L, Nattermann J, Nothacker M, Pox C, Reisinger E, Salzberger B, Salzer H, Weber M, Weinke T, Suerbaum S, Lohse A, Stallmach A
Z GASTROENTEROL. 2015;53(05):418-459.

Patient selection based on treatment duration and liver biochemistry increases success rates after treatment withdrawal in autoimmune hepatitis
Hartl J, Ehlken H, Weiler-Normann C, Sebode M, Kreuels B, Pannicke N, Zenouzi R, Glaubke C, Lohse A, Schramm C
J HEPATOL. 2015;62(3):642-6.

Comparison of autochthonous and imported cases of hepatitis A or hepatitis E
Hartl J, Kreuels B, Polywka S, Addo M, Lütgehetmann M, Dandri-Petersen M, Dammermann W, Sterneck M, Lohse A, Pischke S
Z GASTROENTEROL. 2015;53(7):639-643.

Retroviral insertional mutagenesis in telomerase-immortalized hepatocytes identifies RIPK4 as novel tumor suppressor in human hepatocarcinogenesis
Heim D, Cornils K, Schulze K, Fehse B, Lohse A, Brümmendorf T, Wege H
ONCOGENE. 2015;34(3):385-393.

Ebola and psychological stress of health care professionals
Lehmann M, Brünahl C, Löwe B, Addo M, Schmiedel S, Lohse A, Schramm C
EMERG INFECT DIS. 2015;21(5):913-914.

Psychosoziale Belastungen von Ärzten und Pflegepersonal bei der Behandlung eines mit dem Ebola-Virus infizierten Patienten am Universitätsklinikum Hamburg Eppendorf im September 2014
Lehmann M, Brünahl C, Löwe B, Addo M, Schramm C, Schmiedel S, Lohse A
2015. Psycho - Somatik. .

Diagnostic Criteria for Autoimmune Hepatitis: Scores and More
Lohse A
DIGEST DIS. 2015;33( Suppl. 2):47-52.

Autoimmune Hepatitis - Update 2015
Manns M, Lohse A, Vergani D
J HEPATOL. 2015;62(1 Suppl):S100-S111.

Neue S2k-Leitlinie "Gastrointestinale Infektionen und Morbus Whipple"
Manthey C, Hagel S, Lohse A, Stallmach A
Ärzteblatt Thüringen. 2015;26(12):696-700.

Neue Leitlinie: Wann eine Erregerdiagnostik sinnvoll ist.
Manthey C, Hagel S, Stallmach A, Lohse A
Hamb Ärztebl. 2015;69(11):24-25.

Definition of Chronic Hepatitis E after Liver Transplantation Conforms to Convention
Meisner S, Polywka S, Memmler M, Nashan B, Lohse A, Sterneck M, Pischke S
AM J TRANSPLANT. 2015;15(11):3011-3012.

Quality of life one year post-Shiga Toxin-producing Eschericia coli O104 infection - A prospective cohort study
Riegel B, Broicher W, Wegscheider K, Andresen V, Brähler E, Lohse A, Löwe B
NEUROGASTROENT MOTIL. 2015;27(3):370-378.

Primary Biliary Cirrhosis: Time to Replace a Misnomer: Reply to Giovanni Battista Levi Sandri
Schramm C, Wahl I, Lohse A
HEPATOLOGY. 2015;61(4):1435.

Criteria Used in Clinical Practice to Guide Immunosuppressive Treatment in Patients with PrimarCortico-Cerebellar Structural Connectivity Is Related to Residual Motor Output in Chronic Strokey Sclerosing Cholangitis
Schulze K, Weismüller T, Bubenheim M, Hübener P, Zenouzi R, Lenzen H, Rupp C, Gotthardt D, de Leuw P, Teufel A, Zimmer V, Reiter F, Rust C, Tharun L, Quaas A, Weidemann S, Lammert F, Sarrazin C, Manns M, Lohse A, Schramm C
PLOS ONE. 2015;10(10):Art. e0140525.

Testosterone Suppresses Hepatic Inflammation by the Downregulation of IL-17, CXCL-9, and CXCL-10 in a Mouse Model of Experimental Acute Cholangitis
Schwinge D, Carambia A, Quaas A, Krech T, Wegscheid C, Tiegs G, Prinz I, Lohse A, Herkel J, Schramm C
J IMMUNOL. 2015;194(6):2522-30.

Phenotypic alterations of regulatory T cells in autoimmune hepatitis: causal or associated with treatment and remission?
Sebode M, Peiseler M, Weiler-Normann C, Schramm C, Lohse A, Herkel J
HEPATOLOGY. 2015;61(2):736-737.

Diagnostik und Therapie infektiöser Durchfallerkrankungen Was ist gesichert?
Stallmach A, Hagel S, Lohse A
INTERNIST. 2015;56:1353-1360.

Adjuvant chemotherapy with gemcitabine and cisplatin compared to observation after curative intent resection of cholangiocarcinoma and muscle invasive gallbladder carcinoma (ACTICCA-1 trial) - a randomized, multidisciplinary, multinational phase III trial
Stein A, Arnold D, Bridgewater J, Goldstein D, Jensen L, Klümpen H, Lohse A, Nashan B, Primrose J, Schrum S, Shannon J, Vettorazzi E, Wege H
BMC CANCER. 2015;15:Art. 564.

Temoporfin improves efficacy of photodynamic therapy in advanced biliary tract carcinoma: A multicenter prospective phase II study
Wagner A, Denzer U, Neureiter D, Kiesslich T, Puespoeck A, Rauws E, Emmanuel K, Degenhardt N, Frick U, Beuers U, Lohse A, Berr F, Wolkersdörfer G
HEPATOLOGY. 2015;62(5):1456-65.

Primary biliary "cirrhosis" time to replace a misnomer
Wahl I, Feige A, Löwe B, Weiler-Normann C, Rose M, Lohse A, Schramm C
HEPATOLOGY. 2015;61(3):1091.

High Rate of Cardiac Abnormalities in a Postmortem Analysis of Patients Suffering From Liver Cirrhosis
Wehmeyer M, Heuer A, Benten D, Püschel K, Sydow K, Lohse A, Lüth S
J CLIN GASTROENTEROL. 2015;49(10):866-872.

Efficacy and safety of sofosbuvir-based triple therapy in hepatitis C genotype 4 infection.
Wehmeyer M, Jordan S, Lüth S, Hartl J, Stoehr A, Eißing C, Lohse A, Petersen J, Buggisch P, Schulze zur Wiesch J
DIGEST LIVER DIS. 2015;47(9):811-814.

Immune cell responses are not required to induce substantial hepatitis B virus antigen decline during pegylated interferon-alpha administration
Allweiss L, Volz T, Lütgehetmann M, Giersch K, Bornscheuer T, Lohse A, Petersen J, Ma H, Klumpp K, Fletcher S, Dandri M
J HEPATOL. 2014;60(3):500-7.

Association of autoimmune hepatitis and systemic lupus erythematodes: a case series and review of the literature
Beisel C, Weiler-Normann C, Teufel A, Lohse A
WORLD J GASTROENTERO. 2014;20(35):12662-12667.

TGF-β-dependent induction of CD4⁺CD25⁺Foxp3⁺ Tregs by liver sinusoidal endothelial cells
Carambia A, Freund B, Schwinge D, Heine M, Laschtowitz A, Huber S, Wraith D, Korn T, Schramm C, Lohse A, Heeren J, Herkel J
J HEPATOL. 2014;61(3):594-9.

Genome-wide association study identifies variants associated with autoimmune hepatitis type 1
de Boer Y, van Gerven N, Zwiers A, Verwer B, van Hoek B, van Erpecum K, Beuers U, van Buuren H, Drenth J, den Ouden J, Verdonk R, Koek G, Brouwer J, Guichelaar M, Vrolijk J, Kraal G, Mulder C, van Nieuwkerk C, Fischer J, Berg T, Stickel F, Sarrazin C, Schramm C, Lohse A, Weiler-Normann C, Lerch M, Nauck M, Völzke H, Homuth G, Bloemena E, Verspaget H, Kumar V, Zhernakova A, Wijmenga C, Franke L, Bouma G
GASTROENTEROLOGY. 2014;147(2):443-452.

Transient elastography in primary sclerosing cholangitis-the value as a prognostic factor and limitations
Ehlken H, Lohse A, Schramm C
GASTROENTEROLOGY. 2014;147(2):542-543.

Persistent hepatitis D virus mono-infection in humanized mice is efficiently converted by hepatitis B virus to a productive co-infection
Giersch K, Helbig M, Volz T, Allweiss L, Mancke L, Lohse A, Polywka S, Pollok J, Petersen J, Taylor J, Dandri M, Lütgehetmann M
J HEPATOL. 2014;60(3):538-44.

Development and validation of a prognostic score to predict mortality in patients with acute-on-chronic liver failure
Jalan R, Saliba F, Pavesi M, Amoros A, Moreau R, Ginès P, Levesque E, Durand F, Angeli P, Caraceni P, Hopf C, Alessandria C, Rodriguez E, Solis-Muñoz P, Laleman W, Trebicka J, Zeuzem S, Gustot T, Mookerjee R, Elkrief L, Soriano G, Cordoba J, Morando F, Gerbes A, Agarwal B, Samuel D, Bernardi M, Arroyo V
J HEPATOL. 2014;61(5):1038-1047.

A case of severe Ebola virus infection complicated by gram-negative septicemia
Kreuels B, Wichmann D, Emmerich P, Schmidt-Chanasit J, Heer G, Kluge S, Sow A, Renné T, Günther S, Lohse A, Addo M, Schmiedel S
NEW ENGL J MED. 2014;371(25):2394-401.

Psychological Outcome, Fatigue, and Quality of Life After Infection With Shiga Toxin-Producing Escherichia coli O104
Löwe B, Andresen V, Zimmermann-Fraedrich K, Gappmayer K, Wegscheider K, Treszl A, Riegel B, Rose M, Lohse A, Broicher W

Prevention of hemolytic uremic syndrome with daily bowel lavage in patients with Shiga toxin-producing enterohemorrhagic Escherichia coli O104:H4 infection
Lüth S, Fründt T, Rösch T, Schlee C, Lohse A
JAMA INTERN MED. 2014;174(6):1003-5.

Entwicklung infektiöser Durchfallerkrankungen zwischen den Jahren 2000 und 2012
Lynen Jansen P, Stallmach A, Lohse A, Lerch M
Z GASTROENTEROL. 2014;52(6):549-57.

Gemcitabine plus sorafenib versus gemcitabine alone in advanced biliary tract cancer: a double-blind placebo-controlled multicentre phase II AIO study with biomarker and serum programme
Moehler M, Maderer A, Schimanski C, Kanzler S, Denzer U, Kolligs F, Ebert M, Distelrath A, Geissler M, Trojan J, Schütz M, Berie L, Sauvigny C, Lammert F, Lohse A, Dollinger M, Lindig U, Duerr E, Lubomierski N, Zimmermann S, Wachtlin D, Kaiser A, Schadmand-Fischer S, Galle P, Woerns M, , Denzer U
EUR J CANCER. 2014;50(18):3125-35.

Analysis of the power of common diagnostic tools in the management of acute pancreatitis
Nistal M, Zoltani M, Lohse A, Di Daniele N, Tesauro M, Pace A
GASTROENT RES PRACT. 2014;2014:438697.

Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism
Oehler N, Volz T, Bhadra O, Kah J, Allweiss L, Giersch K, Bierwolf J, Riecken K, Pollok J, Lohse A, Fehse B, Petersen J, Urban S, Lütgehetmann M, Heeren J, Dandri M

Age-related differences in response to peginterferon alfa-2a/ribavirin in patients with chronic hepatitis C infection
Roeder C, Jordan S, Schulze Zur Wiesch J, Pfeiffer-Vornkahl H, Hueppe D, Mauss S, Zehnter E, Stoll S, Alshuth U, Lohse A, Lüth S
WORLD J GASTROENTERO. 2014;20(31):10984-10993.

Autoimmune hepatitis on the rise
Schramm C, Lohse A
J HEPATOL. 2014;60(3):478-479.

Health-related quality of life, depression, and anxiety in patients with autoimmune hepatitis
Schramm C, Wahl I, Weiler-Normann C, Voigt K, Wiegard C, Glaubke C, Brähler E, Löwe B, Lohse A, Rose M
J HEPATOL. 2014;60(3):618-624.

Future perspective: immunomodulatory therapy for autoimmune hepatitis
Sebode M, Lohse A
DIGEST DIS. 2014;32(5):502-506.

Reduced FOXP3(+) regulatory T cells in patients with primary sclerosing cholangitis are associated with IL2RA gene polymorphisms
Sebode M, Peiseler M, Franke B, Schwinge D, Schoknecht T, Wortmann F, Quaas A, Petersen B, Ellinghaus E, Baron U, Olek S, Wiegard C, Weiler-Normann C, Lohse A, Herkel J, Schramm C
J HEPATOL. 2014;60(5):1010-6.

New foe treated with old guns - supportive role of steroids in the treatment of acute severe hepatitis E
Sebode M, Pischke S, Lütgehetmann M, Polywka S, Quaas A, Lohse A, Wege H
BMC GASTROENTEROL. 2014;14(191):.

CD4+ T-cell help is required for effective CD8+ T cell-mediated resolution of acute viral hepatitis in mice
Trautmann T, Kozik J, Carambia A, Richter K, Lischke T, Schwinge D, Mittrücker H, Lohse A, Oxenius A, Wiegard C, Herkel J
PLOS ONE. 2014;9(1):e86348.

Safety and efficacy of protease inhibitor based combination therapy in a single-center "real-life" cohort of 110 patients with chronic hepatitis C genotype 1 infection
Wehmeyer M, Eißing F, Jordan S, Röder C, Hennigs A, Degen O, Hüfner A, Hertling S, Schmiedel S, Sterneck M, Lunzen J, Lohse A, Schulze Zur Wiesch J, Lüth S

Prediction of spontaneous bacterial peritonitis in cirrhotic ascites by a simple scoring system
Wehmeyer M, Krohm S, Kastein F, Lohse A, Lüth S
SCAND J GASTROENTERO. 2014;49(5):595-603.

Reply to: "Anti-TNF-induced autoimmune hepatitis"
Weiler-Normann C, Herkel J, Schramm C, Lohse A
J HEPATOL. 2014;61(1):170-171.

Matrix Conditions and KLF2-Dependent Induction of Heme Oxygenase-1 Modulate Inhibition of HCV Replication by Fluvastatin
Wüstenberg A, Kah J, Singethan K, Sirma H, Keller A, Perez Rosal S, Schrader J, Loscher C, Volz T, Bartenschlager R, Lohmann V, Protzer U, Dandri M, Lohse A, Tiegs G, Sass G
PLOS ONE. 2014;9(5):e96533.

Autoimmune Hepatitis - aktuelle Entwicklungen einer zunehmenden Erkrankung
Zenouzi R, Hartl J, Lohse A
DEUT MED WOCHENSCHR. 2014;139(40):2020-2.

Long-term outcome in PSC/AIH "overlap syndrome": does immunosuppression also treat the PSC component?
Zenouzi R, Lohse A
J HEPATOL. 2014;61(5):1189-1191.

Low Risk of Hepatocellular Carcinoma in Patients With Primary Sclerosing Cholangitis With Cirrhosis
Zenouzi R, Weismüller T, Hübener P, Schulze K, Bubenheim M, Pannicke N, Weiler-Normann C, Lenzen H, Manns M, Lohse A, Schramm C

Inhibition of inflammatory CD4 T cell activity by murine liver sinusoidal endothelial cells
Carambia A, Frenzel C, Bruns O, Schwinge D, Reimer R, Hohenberg H, Huber S, Tiegs G, Schramm C, Lohse A, Herkel J
J HEPATOL. 2013;58(1):112-8.

Increased expression of complement regulators CD55 and CD59 on peripheral blood cells in patients with EAHEC O104:H4 infection
Dammermann W, Schipper P, Ullrich S, Zimmermann-Fraedrich K, Schulze Zur Wiesch J, Fründt T, Tiegs G, Lohse A, Lüth S
PLOS ONE. 2013;8(9):e74880.

Toll like receptor 2 agonists lipoteichoic acid and peptidoglycan are able to enhance antigen specific IFNγ release in whole blood during recall antigen responses
Dammermann W, Wollenberg L, Bentzien F, Lohse A, Lüth S
J IMMUNOL METHODS. 2013;396(1-2):107-15.

EHEC-O104:H4-Ausbruch im Sommer 2011: Charakterisierung der Hamburger Todesfälle
Fründt T, Höpker W, Hagel C, Sperhake J, Isenberg A, Lüth S, Lohse A, Sauter G, Glatzel M, Püschel K
RECHTSMEDIZIN. 2013;23:374–382 .

44-jährige Patientin mit hereditärem nichtpolypösem Kolonkarzinom: Vorsorgeuntersuchungen nichtkolonischer Tumoren
Holzhüter J, Rösch T, Block A, Lohse A, Lüth S
INTERNIST. 2013;54(3):353-8.

A 44-year-old woman with hereditary nonpolyposis colon carcinoma: screening examinations for non-colonic tumors.
Holzhüter J, Rösch T, Block A, Lohse A, Lüth S
INTERNIST. 2013;54:353-358.

Increased T helper type 17 response to pathogen stimulation in patients with primary sclerosing cholangitis
Katt J, Schwinge D, Schoknecht T, Quaas A, Sobottka I, Burandt E, Becker C, Neurath M, Lohse A, Herkel J, Schramm C
HEPATOLOGY. 2013;58(3):1084-93.

Antiviral effect, safety, and pharmacokinetics of five-day oral administration of Deleobuvir (BI 207127), an investigational hepatitis C virus RNA polymerase inhibitor, in patients with chronic hepatitis C
Larrey D, Lohse A, Trepo C, Bronowicki J, Arastéh K, Bourlière M, Calleja J, Stern J, Nehmiz G, Abdallah N, Berger K, Marquis M, Steffgen J, Kukolj G
ANTIMICROB AGENTS CH. 2013;57(10):4727-35.

Not all PBC is the same!
Lohse A, Weiler-Normann C
GASTROENTEROLOGY. 2013;144(3):494-7.

Komorbidität rheumatischer und hepatologischer Erkrankungen
Mayet W, Lohse A
Z RHEUMATOL. 2013;72(6):547-54.

Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis
Moreau R, Jalan R, Gines P, Pavesi M, Angeli P, Cordoba J, Durand F, Gustot T, Saliba F, Domenicali M, Gerbes A, Wendon J, Alessandria C, Laleman W, Zeuzem S, Trebicka J, Bernardi M, Arroyo V
GASTROENTEROLOGY. 2013;144(7):1426-37, 1437.e1-9.

Hepatopulmonary syndrome caused by sarcoidosis of the liver treated with transjugular intrahepatic portosystemic shunt.
Nistal M, Pace A, Klose H, Benten D, Lohse A
THORAX. 2013;68(9):889-890.

Antibiotika-Forschung: Probleme und Perspektiven: Stellungnahme
Reinitzer H, Lohse A, Hacker J

Infiltration of peritumoural but tumour-free parenchyma with IgG4-positive plasma cells in hilar cholangiocarcinoma and pancreatic adenocarcinoma
Resheq Y, Quaas A, von Renteln D, Schramm C, Lohse A, Lüth S
DIGEST LIVER DIS. 2013;45(10):859-65.

Presence of EpCAM-positive circulating tumor cells as biomarker for systemic disease strongly correlates to survival in patients with hepatocellular carcinoma
Schulze K, Gasch C, Staufer K, Nashan B, Lohse A, Pantel K, Riethdorf S, Wege H
INT J CANCER. 2013;133(9):2165-71.

Inflammatorische Erkrankungen mit Leber- und Gelenkbeteiligung. Eine differenzialdiagnostische Herausforderung
Sebode M, Schramm C, Lohse A
INTERNIST. 2013;54(4):441-448.

Decreased frequency of CD73+CD8+ T cells of HIV-infected patients correlates with immune activation and T cell exhaustion
Tóth I, Le A, Hartjen P, Thomssen A, Matzat V, Lehmann C, Scheurich C, Beisel C, Busch C, Degen O, Lohse A, Eiermann T, Fätkenheuer G, Meyer-Olson D, Bockhorn M, Hauber J, Lunzen J, Schulze Zur Wiesch J
J LEUKOCYTE BIOL. 2013;94(4):551-61.

The entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with hepatitis B virus
Volz T, Allweiss L, Ben MBarek M, Warlich M, Lohse A, Pollok J, Alexandrov A, Urban S, Petersen J, Lütgehetmann M, Dandri M
J HEPATOL. 2013;58(5):861-7.

Photodynamic therapy for hilar bile duct cancer: clinical evidence for improved tumoricidal tissue penetration by temoporfin
Wagner A, Kiesslich T, Neureiter D, Friesenbichler P, Puespoek A, Denzer U, Wolkersdörfer G, Emmanuel K, Lohse A, Berr F
PHOTOCH PHOTOBIO SCI. 2013;12(6):1065-73.

Some unusual cystic lesions of the liver
Wehmeyer M, Lohse A, Schramm C
GASTROENTEROLOGY. 2013;145(6):e1-2.

Autoimmune hepatitis: a life-long disease.
Weiler-Normann C, Lohse A
J HEPATOL. 2013;58(1):5-7.

Reply to: "Use of TNFα antagonists in refractory AIH: revealing the unforeseen"
Weiler-Normann C, Schramm C, Lohse A
J HEPATOL. 2013;59(1):198-9.

Infliximab as a rescue treatment in difficult-to-treat autoimmune hepatitis.
Weiler-Normann C, Schramm C, Quaas A, Wiegard C, Glaubke C, Pannicke N, Hübener S, Lohse A
J HEPATOL. 2013;58(3):529-534.

Autoimmune hepatitis 2013 and beyond
Weiler-Normann C, Sebode M, Lohse A
Minerva Gastroenterol Dietol. 2013;59(2):133-41.

Is fatigue in primary biliary cirrhosis cured by transplantation?
Zenouzi R, Weiler-Normann C, Lohse A
J HEPATOL. 2013;59(3):418-9.

Faldaprevir (BI 201335), deleobuvir (BI 207127) and ribavirin oral therapy for treatment-naive HCV genotype 1: SOUND-C1 final results
Zeuzem S, Asselah T, Angus P, Zarski J, Larrey D, Müllhaupt B, Gane E, Schuchmann M, Lohse A, Pol S, Bronowicki J, Roberts S, Arasteh K, Zoulim F, Heim M, Stern J, Nehmiz G, Kukolj G, Böcher W, Mensa F
ANTIVIR THER. 2013;18(8):1015-9.

Faldaprevir and deleobuvir for HCV genotype 1 infection
Zeuzem S, Soriano V, Asselah T, Bronowicki J, Lohse A, Müllhaupt B, Schuchmann M, Bourlière M, Buti M, Roberts S, Gane E, Stern J, Vinisko R, Kukolj G, Gallivan J, Böcher W, Mensa F
NEW ENGL J MED. 2013;369(7):630-9.

Risk factors for development of hemolytic uremic syndrome in a cohort of adult patients with STEC 0104:H4 infection.
Zoufaly A, Cramer J, Vettorazzi E, Sayk F, Bremer J, Koop I, de Weerth A, Schmiedel S, Jordan S, Zimmermann-Fraedrich K, Asselborn N, Nitschke M, Neumann-Grutzeck C, Magnus T, Rüther C, Fellermann K, Stahl R, Wegscheider K, Lohse A
PLOS ONE. 2013;8(3):e59209.

[Intermittent fever under iatrogenic immunosuppression].
Bönstrup M, Schmiedel S, Lohse A
INTERNIST. 2012;53(2):213-217.

Targeting aurora kinases with danusertib (PHA-739358) inhibits growth of liver metastases from gastroenteropancreatic neuroendocrine tumors in an orthotopic xenograft model.
Fraedrich K, Schrader J, Ittrich H, von Amsberg G, Gontarewicz A, Matzat V, Kromminga A, Pace A, Moll J, Bläker M, Lohse A, Hörsch D, Brümmendorf T, Benten D
CLIN CANCER RES. 2012;18(17):4621-4632.

Complications and risk factors in 2731 diagnostic mini-laparoscopies in patients with liver disease.
Frenzel C, Koch J, Lorenzen V, Werner T, Lohse A, Denzer U
LIVER INT. 2012;32(6):970-976.

Acute liver failure following minocycline treatment - a case report and review of the literature.
Kuhn A, Weiler-Normann C, Schramm C, Kluge S, Behne M, Lohse A, Benten D
Z GASTROENTEROL. 2012;50(8):771-775.

Rapid and strong antiviral activity of the non-nucleosidic NS5B polymerase inhibitor BI 207127 in combination with peginterferon alfa 2a and ribavirin.
Larrey D, Lohse A, de Ledinghen V, Trepo C, Gerlach T, Zarski J, Tran A, Mathurin P, Thimme R, Arastéh K, Trautwein C, Cerny A, Dikopoulos N, Schuchmann M, Heim M, Gerken G, Stern J, Wu K, Abdallah N, Girlich B, Scherer J, Berger F, Marquis M, Kukolj G, Böcher W, Steffgen J
J HEPATOL. 2012;57(1):39-46.

Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation.
Lütgehetmann M, Mancke L, Volz T, Helbig M, Allweiss L, Bornscheuer T, Pollok J, Lohse A, Petersen J, Urban S, Dandri-Petersen M
HEPATOLOGY. 2012;55(3):685-694.

[Autoimmune liver diseases].
Pannicke N, Schramm C, Lohse A
INTERNIST. 2012;53(8):943-946.

Autoimmunerkrankungen der Leber
Pannicke N, Schramm C, Lohse A
INTERNIST. 2012;53(8):943-54; quiz 955-6.

FOXP3+ regulatory T cells in autoimmune hepatitis are fully functional and not reduced in frequency
Peiseler M, Sebode M, Franke B, Wortmann F, Schwinge D, Quaas A, Baron U, Olek S, Wiegard C, Lohse A, Weiler-Normann C, Schramm C, Herkel J
J HEPATOL. 2012;57(1):125-132.

An unusual cause of hypertriglyceridemic acute pancreatitis.
Resheq Y, Rinninger F, Lohse A, Schramm C
AM J GASTROENTEROL. 2012;107(6):957-959.

Gallbladder polyps in primary sclerosing cholangitis: indication for early intervention.
Schramm C, Lohse A
HEPATOLOGY. 2012;56(1):396.

Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence.
Schulze Zur Wiesch J, Ciuffreda D, Lewis-Ximenez L, Kasprowicz V, Nolan B, Streeck H, Aneja J, Reyor L, Allen T, Lohse A, McGovern B, Chung R, Kwok W, Kim A, Lauer G
J EXP MED. 2012;209(1):61-75.

Autoimmunerkrankungen mit Leberbeteiligung
Sebode M, Wiegard C, Lohse A
Gastroenterologie up2date. 2012;08(02):129-141.

The indications for liver biopsy.
Tannapfel A, Dienes H, Lohse A
DTSCH ARZTEBL INT. 2012;109(27-28):477-483.

Treatment adherence - room for improvement, not only in autoimmune hepatitis.
Weiler-Normann C, Lohse A
J HEPATOL. 2012;57(6):1168-1170.

Effectiveness and safety of minilaparoscopy-guided spleen biopsy: a retrospective series of 57 cases.
Werner T, Koch J, Frenzel C, Lohse A, Denzer U
SURG ENDOSC. 2012;26(9):2416-2422.

[Pyogenic liver abscess: a retrospective patient study].
Zenouzi R, Schmiedel S, Lohse A
Z GASTROENTEROL. 2012;50(6):578-584.

The transhepatic endotoxin gradient is present despite liver cirrhosis and is attenuated after transjugular portosystemic shunt (TIPS).
Benten D, Schulze Zur Wiesch J, Sydow K, Koops A, Buggisch P, Böger R, Gaydos C, Won H, Franco V, Lohse A, Ray S, Balagopal A

Overlap syndromes: the International Autoimmune Hepatitis Group (IAIHG) position statement on a controversial issue.
Boberg K, Chapman R, Hirschfield G, Lohse A, Manns M, Schrumpf E
J HEPATOL. 2011;54(2):374-385.

Der besondere Fall · Suizidversuch mit Knollenblätterpilz
Harlandt O, Wichmann D, de Heer G, Fischer L, Nashan B, Reimer J, Benten D, Lohse A, Kluge S
Hamb Ärztebl. 2011;65(5):34-35.

Lebensmüde ernten ihr Gift neuerdings im Wald ... Suizidversuch mit Knollenblätterpilz
Harlandt O, Wichmann D, de Heer G, Fischer L, Nashan B, Reimer J, Benten D, Lohse A, Kluge S
Medical Tribune. 2011;43(40):7.

Recognizing autoimmune hepatitis: scores help, but no more.
Lohse A
J HEPATOL. 2011;54(2):193-194.

Rolls Royce for everybody? Diagnosing liver disease by mini-laparoscopy.
Lohse A
J HEPATOL. 2011;54(3):584-585.

Reactivation of autoimmune hepatitis during budesonide monotherapy, and response to standard treatment.
Lohse A, Gil H
J HEPATOL. 2011;54(4):837-839.

Autoimmune hepatitis.
Lohse A, Mieli-Vergani G
J HEPATOL. 2011;55(1):171-182.

Diagnostic criteria for autoimmune hepatitis.
Lohse A, Wiegard C
BEST PRACT RES CL GA. 2011;25(6):665-671.

Hepatitis B virus limits response of human hepatocytes to interferon-α in chimeric mice.
Lütgehetmann M, Bornscheuer T, Volz T, Allweiss L, Bockmann J, Pollok J, Lohse A, Petersen J, Dandri-Petersen M
GASTROENTEROLOGY. 2011;140(7):1-2, 2074-2083.

Chronic inflammatory IFN-γ signaling suppresses hepatocarcinogenesis in mice by sensitizing hepatocytes for apoptosis.
Lüth S, Schrader J, Zander S, Carambia A, Buchkremer J, Huber S, Reifenberg K, Yamamura K, Schirmacher P, Lohse A, Herkel J
CANCER RES. 2011;71(11):3763-3771.

Case report of aseptic meningitis in a patient with Crohn's disease under infliximab therapy.
Manthey C, Lohse A, Pace A
INFLAMM BOWEL DIS. 2011;17(2):10.

A randomized, double-blind, multicenter phase II AIO trial with gemcitabine plus sorafenib versus gemcitabine plus placebo in patients with chemotherapy-naive advanced or metastatic biliary tract cancer: First safety and efficacy data
Moehler M, Schimanski C, Kanzler S, Woerns M, Denzer U, Kolligs F, Ebert M, Distelrath A, Geissler M, Zeuzem S, Lammert F, Lohse A, Dollinger M, Lindig U, Duerr E, Lubomierski N, Zimmermann S, Kabisch M, Schadmann-Fischer S, Galle P
J CLIN ONCOL. 2011;29(15_suppl):4077.

[Lack of data relevant for German transplantation medicine].
Otto G, Lohse A
Z GASTROENTEROL. 2011;49(12):1549-1552.

Role of mycophenolate mofetil in the treatment of autoimmune hepatitis.
Schramm C, Lohse A
J HEPATOL. 2011;55(3):510-511.

Real-Life comparison of pegylated-interferon 2a versus 2b combination therapy of chronic hepatitis C virus.
Schulze Zur Wiesch J, Pudelski N, Hoepner L, Supplieth M, Buggisch P, Lohse A, Lüth S
HEPATOLOGY. 2011;53(4):1405-1407.

Comprehensive analysis of frequency and phenotype of T regulatory cells in HIV infection: CD39 expression of FoxP3+ T regulatory cells correlates with progressive disease.
Schulze Zur Wiesch J, Thomssen A, Hartjen P, Toth I, Lehmann C, Meyer-Olson D, Colberg K, Frerk S, Babikir D, Schmiedel S, Degen O, Mauss S, Rockstroh J, Staszewski S, Khaykin P, Strasak A, Lohse A, Fätkenheuer G, Hauber J, van Lunzen J
J VIROL. 2011;85(3):1287-1297.

Forced activation of β-catenin signaling supports the transformation of hTERT-immortalized human fetal hepatocytes.
Wege H, Heim D, Lütgehetmann M, Dierlamm J, Lohse A, Brümmendorf T
MOL CANCER RES. 2011;9(9):1222-1231.

Pregnancy in primary sclerosing cholangitis.
Wellge B, Sterneck M, Teufel A, Rust C, Franke A, Schreiber S, Berg T, Günther R, Kreisel W, Zu Eulenburg C, Braun F, Beuers U, Galle P, Lohse A, Schramm C
GUT. 2011;60(8):1117-1121.

Efficacy of the protease inhibitor BI 201335, polymerase inhibitor BI 207127, and ribavirin in patients with chronic HCV infection.
Zeuzem S, Asselah T, Angus P, Zarski J, Larrey D, Müllhaupt B, Gane E, Schuchmann M, Lohse A, Pol S, Bronowicki J, Roberts S, Arasteh K, Zoulim F, Heim M, Stern J, Kukolj G, Nehmiz G, Haefner C, Boecher W
GASTROENTEROLOGY. 2011;141(6):2014-2047.

CCK1 and CCK2 receptors are expressed on pancreatic stellate cells and induce collagen production.
Berna M, Seiz O, Nast J, Benten D, Bläker M, Koch J, Lohse A, Pace A
J BIOL CHEM. 2010;285(50):38905-38914.

Orthotopic Liver Transplantation: Is There a Risk for Listeria monocytogenes Infection?
Ehehalt U, Schmiedel S, Lohse A
CASE REP MED. 2010;2010:901894.

Immune-mediated liver injury.
Lohse A, Weiler-Normann C, Tiegs G
J HEPATOL. 2010;52:136-144.

Wissensstand, Präventionsverhalten und Therapieadhärenz von Patienten mit chronischer Hepatitis B in einem großen tertiären Zentrum in Deutschland
Lutgehetmann M, Meyer F, Volz T, Lohse A, Fischer C, Dandri M, Petersen J
Z GASTROENTEROL. 2010;48(9):1126-32.

[Knowledge about HBV, prevention behaviour and treatment adherence of patients with chronic hepatitis B in a large referral centre in Germany].
Lütgehetmann M, Meyer F, Volz T, Lohse A, Fischer C, Dandri-Petersen M, Petersen J
Z GASTROENTEROL. 2010;48(9):1126-1132.

In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice.
Lütgehetmann M, Volz T, Köpke A, Broja T, Tigges E, Lohse A, Fuchs E, Murray J, Petersen J, Dandri-Petersen M
HEPATOLOGY. 2010;52(1):16-24.

Budesonide induces remission more effectively than prednisone in a controlled trial of patients with autoimmune hepatitis.
Manns M, Woynarowski M, Kreisel W, Lurie Y, Rust C, Zuckerman E, Bahr M, Günther R, Hultcrantz R, Spengler U, Lohse A, Szalay F, Färkkilä M, Pröls M, Strassburg C
GASTROENTEROLOGY. 2010;139(4):1198-1206.

[A rare cause of variceal bleeding].
Naderi J, Lohse A, Galle P, Schramm C
Z GASTROENTEROL. 2010;48(10):1215-1218.

Seltene Ursache einer Fundusvarizenblutung
Naderi J, Lohse A, Galle P, Schramm C
Z GASTROENTEROL. 2010;48(10):1215-8.

Human SepSecS or SLA/LP: selenocysteine formation and autoimmune hepatitis.
Palioura S, Herkel J, Simonovi M, Lohse A, Söll D
BIOL CHEM. 2010;391(7):771-776.

Primary liver transplantation for autoimmune Hepatitis: A comparative analysis of the European Liver Transplant Registry
Schramm C, Bubenheim M, Adam R, Karam V, Buckels J, O'Grady J, Jamieson N, Pollard S, Neuhaus P, Manns M, Porte R, Castaing D, Paul A, Traynor O, Garden J, Friman S, Ericzon B, Fischer L, Vitko S, Krawczyk M, Metselaar H, Foss A, Kilic M, Rolles K, Burra P, Rogiers X, Lohse A
LIVER TRANSPLANT. 2010;16(4):461-469.

Treatment response in patients with autoimmune hepatitis.
Schramm C, Weiler-Normann C, Wiegard C, Hellweg S, Müller S, Lohse A
HEPATOLOGY. 2010;52(6):2247-2248.

Concurrent autoimmune diseases in patients with autoimmune hepatitis.
Teufel A, Weinmann A, Kahaly G, Centner C, Piendl A, Wörns M, Lohse A, Galle P, Kanzler S
J CLIN GASTROENTEROL. 2010;44(3):208-213.

Immune tolerance: what is unique about the liver.
Tiegs G, Lohse A
J AUTOIMMUN. 2010;34:1-6.

Letzte Aktualisierung aus dem FIS: 05.12.2023 - 00:38 Uhr