Tobias Lange
Prof. Dr. med.
Tobias Lange
PhD
  • Wissenschaftlicher Mitarbeiter
  • Facharzt für Anatomie
Arbeitsbereich

Standort

N62 , EG, Raumnummer 1
Sprachen
Deutsch (Muttersprache)
Englisch

Fachgebiete

Tätigkeitsschwerpunkte

Publikationen

Zurück
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011
  • 2009
  • 2008
Vor

A functional ex vivo assay to detect PARP1-EJ repair and radiosensitization by PARP-inhibitor in prostate cancer
Köcher S, Beyer B, Lange T, Nordquist L, Volquardsen J, Burdak-Rothkamm S, Schlomm T, Petersen C, Rothkamm K, Mansour W
INT J CANCER. 2019;144(7):1685-1696.

Probennahme per Laserablation von Krebsgeweben für Proteomics
Lange T, Schlüter H
BIOspektrum. 2019;25(1):32-34.

Effect of the actin- and calcium-regulating activities of ITPKB on the metastatic potential of lung cancer cells
Bäder S, Glaubke E, Grüb S, Muhs S, Wellbrock J, Nalaskowski M, Lange T, Windhorst S
BIOCHEM J. 2018;475(12):2057-2071.

Knockdown of L1CAM significantly reduces metastasis in a xenograft model of human melanoma: L1CAM is a potential target for anti-melanoma therapy
Ernst A, Putscher A, Samatov T, Suling A, Galatenko V, Shkurnikov M, Knyazev E, Tonevitsky A, Haalck T, Lange T, Maar H, Schröder-Schwarz J, Riecken K, Schumacher U, Wicklein D
PLOS ONE. 2018;13(2):e0192525.

Locally Ablative Radiation Therapy of a Primary Human Small Cell Lung Cancer Tumor Decreases the Number of Spontaneous Metastases in Two Xenograft Models
Frenzel T, Siekmann J, Grohmann C, Valentiner U, Schmitz R, Riecken K, Fehse B, Schumacher U, Lange T, Krüll A
INT J RADIAT ONCOL. 2018;100(4):1044-1056.

Differential Proteome Analysis of Human Neuroblastoma Xenograft Primary Tumors and Matched Spontaneous Distant Metastases
Hänel L, Gosau T, Maar H, Valentiner U, Schumacher U, Riecken K, Windhorst S, Hansen N, Heikaus L, Wurlitzer M, Nolte I, Schlüter H, Lange T
SCI REP-UK. 2018;8(1):13986.

Development and Characterization of a Spontaneously Metastatic Patient-Derived Xenograft Model of Human Prostate Cancer
Lange T, Oh-Hohenhorst S, Joosse S, Pantel K, Hahn O, Gosau T, Dyshlovoy S, Wellbrock J, Feldhaus S, Maar H, Gehrcke R, Kluth M, Simon R, Schlomm T, Huland H, Schumacher U
SCI REP-UK. 2018;8:17535.

Clinical relevance of cytoskeleton associated proteins for ovarian cancer
Schiewek J, Schumacher U, Lange T, Joosse S, Wikman H, Pantel K, Mikhaylova M, Kneussel M, Linder S, Schmalfeldt B, Oliveira-Ferrer L, Windhorst S
J CANCER RES CLIN. 2018;144(11):2195-2205.

CEACAM1 promotes melanoma metastasis and is involved in the regulation of the EMT associated gene network in melanoma cells
Wicklein D, Otto B, Suling A, Elies E, Lüers G, Lange T, Feldhaus S, Maar H, Schröder-Schwarz J, Brunner G, Wagener C, Schumacher U
SCI REP-UK. 2018;8:11893.

Strong fascin expression promotes metastasis independent of its F-actin bundling activity
Heinz L, Muhs S, Schiewek J, Grüb S, Nalaskowski M, Lin Y, Wikman H, Oliveira-Ferrer L, Lange T, Wellbrock J, Konietzny A, Mikhaylova M, Windhorst S
ONCOTARGET. 2017;8(66):110077-110091.

Selection and Characterization of an α6β4 Integrin blocking DNA Aptamer
Berg K, Lange T, Mittelberger F, Schumacher U, Hahn U
MOL THER-NUCL ACIDS. 2016;5:e294.

Marine compound rhizochalinin shows high in vitro and in vivo efficacy in castration resistant prostate cancer
Dyshlovoy S, Otte K, Alsdorf W, Hauschild J, Lange T, Venz S, Bauer C, Bähring R, Amann K, Mandanchi R, Schumacher U, Schröder-Schwarz J, Makarieva T, Guzii A, Tabakmakher K, Fedorov S, Shubina L, Kasheverov I, Ehmke H, Steuber T, Stonik V, Bokemeyer C, Honecker F, von Amsberg G
ONCOTARGET. 2016;7(43):69703 - 69717.

Downregulation of AKT3 Increases Migration and Metastasis in Triple Negative Breast Cancer Cells by Upregulating S100A4
Grottke A, Ewald F, Lange T, Nörz D, Herzberger C, Bach J, Grabinski N, Gräser L, Höppner F, Nashan B, Schumacher U, Jücker M
PLOS ONE. 2016;11(1):e0146370.

Intracellular and extracellular microRNA: An update on localization and biological role
Makarova J, Shkurnikov M, Wicklein D, Lange T, Samatov T, Turchinovich A, Tonevitsky A
PROG HISTOCHEM CYTO. 2016;51(3-4):33-49.

Drosophila homologue of Diaphanous 1 (DIAPH1) controls the metastatic potential of colon cancer cells by regulating microtubule-dependent adhesion
Lin Y, Bhuwania R, Gromova K, Failla A, Lange T, Riecken K, Linder S, Kneussel M, Izbicki J, Windhorst S
ONCOTARGET. 2015;6(21):18577-89.

SDA, a DNA aptamer inhibiting E- and P-selectin mediated adhesion of cancer and leukemia cells, the first and pivotal step in transendothelial migration during metastasis formation
Faryammanesh R, Lange T, Magbanua E, Haas S, Meyer C, Wicklein D, Schumacher U, Hahn U
PLOS ONE. 2014;9(4):e93173.

Aberrant presentation of HPA-reactive carbohydrates implies Selectin-independent metastasis formation in human prostate cancer
Lange T, Kupfernagel M, Wicklein D, Gebauer F, Maar H, Brügge K, Müller I, Simon R, Schlomm T, Sauter G, Schumacher U
CLIN CANCER RES. 2014;20(7):1791-802.

Importance of altered glycoprotein-bound N- and O-glycans for epithelial-to-mesenchymal transition and adhesion of cancer cells
Lange T, Samatov T, Tonevitsky A, Schumacher U
CARBOHYD RES. 2014;389:39-45.

Expression of DIAPH1 is up-regulated in colorectal cancer and its down-regulation strongly reduces the metastatic capacity of colon carcinoma cells
Lin Y, Izbicki J, König A, Habermann J, Blechner C, Lange T, Schumacher U, Windhorst S
INT J CANCER. 2014;134(7):1571-82.

Expression of the coxsackie adenovirus receptor in neuroendocrine lung cancers and its implications for oncolytic adenoviral infection.
Wunder T, Schmid K, Wicklein D, Groitl P, Dobner T, Lange T, Anders M, Schumacher U
CANCER GENE THER. 2013;20(1):25-32.

Divergent resorbability and effects on osteoclast formation of commonly used bone substitutes in a human in vitro-assay.
Keller J, Brink S, Busse B, Schilling A, Schinke T, Amling M, Lange T
PLOS ONE. 2012;7(10):46757.

Human prostate cancer in a clinically relevant xenograft mouse model: identification of β(1,6)-branched oligosaccharides as a marker of tumor progression.
Lange T, Ullrich S, Müller I, Nentwich M, Stübke K, Feldhaus S, Knies C, Hellwinkel O, Vessella R, Abramjuk C, Anders M, Schröder-Schwarz J, Schlomm T, Huland H, Sauter G, Schumacher U
CLIN CANCER RES. 2012;18(5):1364-1373.

p65-Dependent production of interleukin-1β by osteolytic prostate cancer cells causes an induction of chemokine expression in osteoblasts.
Schulze J, Riecken K, Baranowsky A, Streichert T, Lange T, Spiro A, Albers J, Seitz S, Zustin J, Amling M, Fehse B, Schinke T
CANCER LETT. 2012;317(1):106-113.

Neuronal differentiation by indomethacin and IBMX inhibits proliferation of small cell lung cancer cells in vitro.
Lange A, Gustke H, Glassmeier G, Heine M, Zangemeister-Wittke U, Schwarz J, Schumacher U, Lange T
LUNG CANCER. 2011;74(2):178-187.

Trastuzumab has anti-metastatic and anti-angiogenic activity in a spontaneous metastasis xenograft model of esophageal adenocarcinoma.
Lange T, Nentwich M, Lueth M, Yekebas E, Schumacher U
CANCER LETT. 2011;308(1):54-61.

Size dependent induction of proinflammatory cytokines and cytotoxicity of particulate beta-tricalciumphosphate in vitro.
Lange T, Schilling A, Peters F, Mujas J, Wicklein D, Amling M
BIOMATERIALS. 2011;32(17):4067-4075.

Adhesion of small cell lung cancer cells to E- and P-selectin under physiological flow conditions: implications for metastasis formation.
Richter U, Schröder C, Wicklein D, Lange T, Geleff S, Dippel V, Schumacher U, Klutmann S
Histochem Cell Biol. 2011;135(5):499-512.

Proinflammatory and osteoclastogenic effects of beta-tricalciumphosphate and hydroxyapatite particles on human mononuclear cells in vitro.
Lange T, Schilling A, Peters F, Haag F, Morlock M, Rueger J, Amling M
BIOMATERIALS. 2009;30(29):5312-5318.

Gap junctional communication in human osteoclasts in vitro and in vivo.
Schilling A, Filke S, Lange T, Gebauer M, Brink S, Baranowsky A, Zustin J, Amling M
J CELL MOL MED. 2008;12(6):2497-2504.

Letzte Aktualisierung aus dem FIS: 15.12.2019 - 00:38 Uhr