Dr. rer. nat. Dipl.-Biol.
Jakob Körbelin
  • Wissenschaftler
Arbeitsbereich

Standort

Campus Forschung N27 , EG, Raumnummer 00.061
Sprachen
Deutsch (Muttersprache)
Englisch

Tätigkeitsschwerpunkte

Auszeichnungen

Publikationen

Zurück
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2012
  • 2011
Vor

Nanobody-Enhanced Targeting of AAV Gene Therapy Vectors
Eichhoff A, Börner K, Albrecht B, Schäfer W, Baum N, Haag F, Körbelin J, Trepel M, Braren I, Grimm D, Adriouch S, Koch-Nolte F
MOL THER-METH CLIN D. 2019;15:211-220.

The P2-receptor-mediated Ca2+ signalosome of the human pulmonary endothelium - implications for pulmonary arterial hypertension
Hennigs J, Lüneburg N, Stage A, Schmitz M, Körbelin J, Harbaum L, Matuszcak C, Mienert J, Bokemeyer C, Böger R, Kiefmann R, Klose H
PURINERG SIGNAL. 2019;15(3):299-311.

Endothelium-Derived Semaphorin 3G Regulates Hippocampal Synaptic Structure and Plasticity via Neuropilin-2/PlexinA4
Tan C, Lu N, Wang C, Chen D, Sun N, Lyu H, Körbelin J, Shi W, Fukunaga K, Lu Y, Han F
NEURON. 2019;101(5):920-937.e13.

Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1
Yousef H, Czupalla C, Lee D, Chen M, Burke A, Zera K, Zandstra J, Berber E, Lehallier B, Mathur V, Nair R, Bonanno L, Yang A, Peterson T, Hadeiba H, Merkel T, Körbelin J, Schwaninger M, Buckwalter M, Quake S, Butcher E, Wyss-Coray T
NAT MED. 2019;25(6):988-1000.

Novel Gene Therapy Approaches for Whole Brain Delivery of the Lysosomal Gcase Enzyme for Wide Protection from Alpha-Synuclein Toxic Aggregates
Broccoli V, Ordozza G, Bido S, Valtorta M, Morabito G, Körbelin J, Cacellieri C, Giannelli S
MOL THER. 2018;26(5 Suppl.):131-131.

Assessing the transduction profile of the brain-endothelial directed gene vector AAV-BR1
Körbelin J, Kleint M, Dogbevia G, Ohnmacht J, Trepel M, Schwaninger M
N-S ARCH PHARMACOL. 2018;(391):.

Gene Therapy Decreases Seizures in a Model of Incontinentia Pigmenti
Dogbevia G, Töllner K, Körbelin J, Bröer S, Ridder D, Grasshoff H, Brandt C, Wenzel J, Straub B, Trepel M, Löscher W, Schwaninger M
ANN NEUROL. 2017;82(1):93-104.

Brain Endothelial-Targeted Gene Therapy in a Mouse Model of Incontinentia Pigmenti
Körbelin J, Dogbevia G, Töllner K, Bröer S, Ridder D, Grasshoff H, Brandt C, Straub B, Trepel M, Löscher W, Schwaninger M
MOL THER. 2017;25(5):256-257.

Optimization of design and production strategies for novel adeno-associated viral display peptide libraries
Körbelin J, Hunger A, Alawi M, Sieber T, Binder M, Trepel M
GENE THER. 2017;24(8):470-481.

Viral vector for the targeted transfer of genes in the brain and spinal cord
Körbelin J, Michelfelder S, Trepel M
2017.

How to successfully screen random AAV display peptide libraries in vivo
Körbelin J, Trepel M
HUM GENE THER METHOD. 2017;28(3):109-123.

Genetic manipulation of brain endothelial cells in vivo
Assmann J, Körbelin J, Schwaninger M
BBA-MOL BASIS DIS. 2016;1862(3):381-94.

A brain microvasculature endothelial cell-specific viral vector with the potential to treat neurovascular and neurological diseases
Körbelin J, Dogbevia G, Michelfelder S, Ridder D, Hunger A, Wenzel J, Seismann H, Lampe M, Bannach J, Pasparakis M, Kleinschmidt J, Schwaninger M, Trepel M
EMBO MOL MED. 2016;8(6):609-25.

Vascular-targeted recombinant adeno-associated viral vectors for the treatment of rare diseases
Körbelin J, Schwaninger M, Trepel M
Rare Diseases. 2016;4(1):.

Pulmonary Targeting of Adeno-associated Viral Vectors by Next-generation Sequencing-guided Screening of Random Capsid Displayed Peptide Libraries
Körbelin J, Sieber T, Michelfelder S, Lunding L, Spies E, Hunger A, Alawi M, Rapti K, Indenbirken D, Müller O, Pasqualini R, Arap W, Kleinschmidt J, Trepel M
MOL THER. 2016;24(6):1050-61.

Erratum for "Treatment of multifocal breast cancer by systemic delivery of dual-targeted adeno-associated viral vectors"
Trepel M, Körbelin J, Spies E, Heckmann M, Hunger A, Fehse B, Katus H, Kleinschmidt J, Müller O, Michelfelder S
GENE THER. 2015;22(10):840-847.

Treatment of multifocal breast cancer by systemic delivery of dual-targeted adeno-associated viral vectors
Trepel M, Körbelin J, Spies E, Heckmann M, Hunger A, Fehse B, Katus H, Kleinschmidt J, Müller O, Michelfelder S
GENE THER. 2015;22(10):840-7.

Neue Peptide mit Spezifität für die Lunge
Trepel M, Körbelin J, Michelfelder S
2014.

The complete sequence of tobacco mosaic virus isolate Ohio V reveals a high accumulation of silent mutations in all open reading frames
Körbelin J, Willingmann P, Adam G, Heinze C
ARCH VIROL. 2012;157(2):387-9.

Peptide ligands incorporated into the threefold spike capsid domain to re-direct gene transduction of AAV8 and AAV9 in vivo.
Michelfelder S, Varadi K, Raupp C, Hunger A, Körbelin J, Pahrmann C, Schrepfer S, Müller O, Kleinschmidt J, Trepel M
PLOS ONE. 2011;6(8):23101.

Letzte Aktualisierung aus dem FIS: 12.11.2019 - 00:35 Uhr

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