Samuel Huber
Prof. Dr. med.
Samuel Huber
  • Leiter der molekularen Gastroenterologie und Immunologie
  • Heisenberg-Professur für Intestinale Immunregulation
  • Oberarzt
  • Facharzt für Innere Medizin
Arbeitsbereich
Kontakt
Telefon
+49 (0) 40 7410 - 57273
Telefax
+49 (0) 40 7410 - 59038
E-Mail
shuber@uke.de
Standort
Campus Forschung N27 , 4. Etage, Raumnummer 04.038
Sprachen
Deutsch (Muttersprache)
Englisch

Tätigkeitsschwerpunkte

  • Chronisch entzündliche Darmerkrankungen

Lebenslauf

Auszeichnungen

  • Postdoctoral Fellowship award der „Crohn's and Colitis Foundation of America“

  • Ernst Jung-Karriere-Förder-Preis für medizinische Forschung

  • Peter Hans Hofschneider Stiftungsprofessur

  • Heisenberg Professur für Intestinale Immunregulation

Mitgliedschaften

  • DGVS

  • DGIM

  • ECCO

Publikationen

  • Brockmann, L., Gagliani, N., Steglich, B., Giannou, A.D., Kempski, J., Pelczar, P., Geffken, M., Mfarrej, B., Huber, F., Herkel, J., Wan, Y.Y., Esplugues, E., Battaglia, M., Krebs, C.F., Flavell, R.A.*, and Huber, S.* (*equally contributing senior authors). (2017) IL-10 Receptor Signaling Is Essential for TR1 Cell Function In Vivo. J Immunol. 198, 1130-1141

  • Pelczar, P., Witkowski, M., Perez, L.G., Kempski, J., Hammel, A.G., Brockmann, L., Kleinschmidt, D., Wende, S., Haueis, C., Bedke, T., Witkowski, M., Krasemann, S., Steurer, S., Booth, C.J., Busch, P., Konig, A., Rauch, U., Benten, D., Izbicki, J.R., Rosch, T., Lohse, A.W., Strowig, T., Gagliani, N., Flavell, R.A.*, and Huber, S.* (*equally contributing senior authors). (2016) A pathogenic role for T cell-derived IL-22BP in inflammatory bowel disease. Science 354, 358-362.

  • Gagliani, N., M. C. Vesely, A. Iseppon, L. Brockmann, H. Xu, N. W. Palm, M. R. de Zoete, P. Licona-Limon, R. S. Paiva, T. Ching, C. Weaver, X. Zi, X. Pan, R. Fan, L. X. Garmire, M. J. Cotton, Y. Drier, B. Bernstein, J. Geginat, B. Stockinger, E. Esplugues, S. Huber*, and R. A. Flavell* (*equally contributing senior authors). (2015). Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation. Nature 523, 221-225

  • Gagliani, N.*, Magnani, C.F.*, Huber, S.* (*equally contributing authors), Gianolini, M.E., Pala, M., Licona-Limon, P., Guo, B., Herbert, D.R., Bulfone, A., Trentini, F., Di Serio, C., Bacchetta, R., Andreani, M., Brockmann, L., Gregori, S., Flavell, R. A., Roncarolo, M. G. (2013). Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells. Nat Med. 19, 739-46.

  • Huber, S.*, Gagliani, N.* (*equally contributing authors), Zenewicz, L.A., Huber, F.J., Bosurgi, L., Hu, B., Hedl, M., Zhang, W., O’Connor, W., Murphy, A.J., Valenzuela, D.M., Yancopoulos, G.D., Booth, C.J. Cho, J.H., Ouyang, W., Abraham, C., and Flavell, R.A. (2012). IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine. Nature 491, 259-263. (S.H and R.A.F. are co-corresponding authors)

  • Esplugues, E.*, Huber, S.* (*equally contributing authors), Gagliani, N., Hauser, A.E., Town, T., Wan, Y.Y., O'Connor, W., Jr., Rongvaux, A., Van Rooijen, N., Haberman, A.M., Iwakura, Y., Kuchroo, V.K., Kolls, J.K., Bluestone, J.A., Herold, K.C., and Flavell, R.A. (2011). Control of TH17 cells occurs in the small intestine. Nature 475, 514-518.

  • Huber, S.*, Gagliani, N.*, Esplugues, E.* (*equally contributing authors), O'Connor, W., Jr., Huber, F.J., Chaudhry, A., Kamanaka, M., Kobayashi, Y., Booth, C.J., Rudensky, A.Y., Roncarolo, M.G., Battaglia, M., and Flavell, R.A. (2011). Th17 cells express interleukin-10 receptor and are controlled by Foxp3 and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner. Immunity 34, 554-565.

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