Sandra Blois
Univ.-Prof. Dr. rer. nat.
Sandra Maria Blois
PhD
  • Glycoimmunologie und Reproduktion
Arbeitsbereich

Kontakt

Standort

N26 , 2. Etage, Raumnummer 205
Sprachen
Spanisch (Muttersprache)
Englisch
Deutsch
Italienisch

Fachgebiete

Publikationen

Zurück
  • 2025
  • 2024
  • 2023
  • 2022
  • 2021
  • 2020
  • 2019
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011
  • 2009
  • 2008
  • 2007
  • 2006
  • 2005
  • 2004
Vor

2023 ISIR Meeting as the Impetus for Centers for Reproductive Sciences (CERES): Driving reproductive health research forward in Germany
Blois S, Diemert A
J REPROD IMMUNOL. 2025;170:104618.

Platelet-Immune Cell Communication in Pregnancy: Exploring a New Frontier in Maternal Immunology
Kohli S, Blois S
J THROMB HAEMOST. 2025 [Epub ahead of print].

Maternal and placental galectins: key players in the feto-maternal symbiotic tango
Oravecz O, Xie Y, Balogh A, Posta M, Harms C, Farkas E, Borowski S, Szekeres-Barthó J, Than N, Blois S
SEMIN IMMUNOPATHOL. 2025;47(1):35.

High-Sensitivity Cardiac Troponin I Enhances Preeclampsia Prediction Beyond Maternal Factors and the sFlt-1/PlGF Ratio
Bacmeister L, Goßling A, Buellesbach A, Birukov A, Myers J, Thomas S, Lee S, Andersen M, Jorgensen J, Diemert A, Blois S, Arck P, Hecher K, Herse F, Blankenberg S, Dechend R, Westermann D, Zeller T
CIRCULATION. 2024;149(2):95-106.

Placental glycosylation senses the anti-angiogenic milieu induced by human sFLT1 during pregnancy
Kirkgöz K, Vogtmann R, Xie Y, Zhao F, Riedel A, Adam L, Freitag N, Harms C, Garcia M, Plösch T, Gellhaus A, Blois S
J REPROD IMMUNOL. 2024;164:.

Modulation of galectin-9 mediated responses in monocytes and T-cells by pregnancy-specific glycoprotein 1
Mendoza M, Ballesteros A, Rendon-Correa E, Tonk R, Warren J, Snow A, Stowell S, Blois S, Dveksler G
J BIOL CHEM. 2024;300(9):.

Dissecting humoral immune responses to an MVA-vectored MERS-CoV vaccine in humans using a systems serology approach
Weskamm L, Tarnow P, Harms C, Huchon M, Raadsen M, Friedrich M, Rübenacker L, Grüttner C, Garcia M, Koch T, Becker S, Sutter G, Lhomme E, Haagmans B, Fathi A, Blois S, Dahlke C, Richert L, Addo M
ISCIENCE. 2024;27(8):110470.

Fetal growth restriction induced by maternal gal-3 deficiency is associated with altered gut-placenta axis
Xie Y, Zhao F, Wang Y, Borowski S, Freitag N, Tirado-Gonzalez I, Hofsink N, Matschl U, Plösch T, Garcia M, Blois S
CELL DEATH DIS. 2024;15(8):.

Maternal-derived galectin-1 shapes the placenta niche through Sda terminal glycosylation: Implication for preeclampsia
Xie Y, Zhao F, Freitag N, Borowski S, Wang Y, Harms C, Pang P, Desforges J, Wen T, Schwedhelm E, Singh M, Dechend R, Dell A, Haslam S, Dveksler G, Garcia M, Blois S
PNAS NEXUS. 2023;2(8):.

A unique maternal and placental galectin signature upon SARS-CoV-2 infection suggests galectin-1 as a key alarmin at the maternal-fetal interface
Zhao F, Tallarek A, Wang Y, Xie Y, Diemert A, Lu-Culligan A, Vijayakumar P, Kittmann E, Urbschat C, Bayo J, Arck P, Farhadian S, Dveksler G, Garcia M, Blois S
FRONT IMMUNOL. 2023;14:1196395.

Editorial: The placenta, fetomaternal tolerance and beyond: A tribute to Sir Peter Medawar on the 60th anniversary of his Nobel Prize
Barrientos G, Solano M, Blois S, Sharma S
FRONT IMMUNOL. 2022;13:.

Examination of the Contributions of Maternal/Placental-Derived Galectin-1 to Pregnancy Outcome
Borowski S, Freitag N, Urban I, Michel G, Barrientos G, Blois S
2022. Galectins. Stowell S, Arthur C, Cummings R (Hrsg.). 1. Aufl. New York, NY: Humana Press, 603-619.

Soluble CD146 is increased in preeclampsia and interacts with galectin-1 to regulate trophoblast migration through VEGFR2 receptor
Bouvier S, Traboulsi W, Blois S, Demattei C, Joshkon A, Mousty E, Nollet M, Paulmyer-Lacroix O, Foucault-Bertaud A, Fortier M, Leroyer A, Bachelier R, Letouzey V, Alfaidy N, Dignat-George F, Blot-Chabaud M, Gris J, Bardin N
F&S science. 2022;3(1):84-94.

Acceleration of TAA-Induced Liver Fibrosis by Stress Exposure Is Associated with Upregulation of Nerve Growth Factor and Glycopattern Deviations
Atorrasagasti C, Piccioni F, Borowski S, Tirado-González I, Freitag N, Cantero M, Bayo J, Mazzolini G, Alaniz L, Blois S, Garcia M
INT J MOL SCI. 2021;22(10):.

Placental Glycoredox Dysregulation Associated with Disease Progression in an Animal Model of Superimposed Preeclampsia
Blois S, Prince P, Borowski S, Galleano M, Barrientos G
CELLS-BASEL. 2021;10(4):.

Phenotyping placental oxygenation in Lgals1 deficient mice using 19F MRI
Boehm-Sturm P, Mueller S, Freitag N, Borowski S, Foddis M, Koch S, Temme S, Flögel U, Blois S
SCI REP-UK. 2021;11(1):2126.

Galectin-Levels Are Elevated in Infants Born Preterm Due to Amniotic Infection and Rapidly Decline in the Neonatal Period
Faust K, Freitag N, Barrientos G, Hartel C, Blois S
FRONT IMMUNOL. 2021;11:.

Expression of the alternative splicing regulator Rbfox2 during placental development is differentially regulated in preeclampsia mouse models
Freitag N, Xie Y, Adam L, Borowski S, Blois S, Barrientos G
AM J REPROD IMMUNOL. 2021;86(6):e13491.

Targeted disruption of galectin 3 in mice delays the first wave of spermatogenesis and increases germ cell apoptosis
Lei T, Blois S, Freitag N, Bergmann M, Bhushan S, Wahle E, Huang A, Chen H, Hartmann M, Wudy S, Liu F, Meinhardt A, Fijak M
CELL MOL LIFE SCI. 2021;78(7):3621-3635.

Medawar's PostEra: Galectins Emerged as Key Players During Fetal-Maternal Glycoimmune Adaptation
Menkhorst E, Than N, Jeschke U, Barrientos G, Szereday L, Dveksler G, Blois S
FRONT IMMUNOL. 2021;12:.

Immunobiology of Gestational Diabetes Mellitus in Post-Medawar Era
Sharma S, Banerjee S, Krueger P, Blois S
FRONT IMMUNOL. 2021;12:.

Role of galectin-glycan circuits in reproduction: from healthy pregnancy to preterm birth (PTB)
Blois S, Verlohren S, Wu G, Clark G, Dell A, Haslam S, Barrientos G
SEMIN IMMUNOPATHOL. 2020;42(4):469-486.

Altered Glycosylation Contributes to Placental Dysfunction Upon Early Disruption of the NK Cell-DC Dynamics
Borowski S, Tirado-Gonzalez I, Freitag N, Garcia M, Barrientos G, Blois S
FRONT IMMUNOL. 2020;11:1316.

The chimera-type galectin-3 is a positive modulator of trophoblast functions with dysregulated expression in gestational diabetes mellitus
Freitag N, Tirado-González I, Barrientos G, Cohen M, Daher S, Goldman-Wohl D, Mincheva-Nilsson L, John C, Jeschke U, Blois S
AM J REPROD IMMUNOL. 2020;84(6):e13311.

Galectin-3 deficiency in pregnancy increases the risk of fetal growth restriction (FGR) via placental insufficiency
Freitag N, Tirado-Gonzalez I, Barrientos G, Powell K, Boehm-Sturm P, Koch S, Hecher K, Staff A, Arck P, Diemert A, Blois S
CELL DEATH DIS. 2020;11(7):560.

Glycan characterization of pregnancy-specific glycoprotein 1 and its identification as a novel Galectin-1 ligand
Mendoza M, Lu D, Ballesteros A, Blois S, Abernathy K, Feng C, Dimitroff C, Zmuda J, Panico M, Dell A, Vasta G, Haslam S, Dveksler G
GLYCOBIOLOGY. 2020;30(11):895-909.

Pregnancy Galectinology: Insights Into a Complex Network of Glycan Binding Proteins
Blois S, Dveksler G, Vasta G, Freitag N, Blanchard V, Barrientos G
FRONT IMMUNOL. 2019;10:1166.

Interaction of Pregnancy-Specific Glycoprotein 1 With Integrin Α5β1 Is a Modulator of Extravillous Trophoblast Functions
Rattila S, Dunk C, Im M, Grichenko O, Zhou Y, Yanez-Mo M, Blois S, Yamada K, Erez O, Gomez-Lopez N, Lye S, Hinz B, Romero R, Cohen M, Dveksler G
CELLS-BASEL. 2019;8(11):.

Defective trophoblast invasion underlies fetal growth restriction and preeclampsia-like symptoms in the stroke-prone spontaneously hypertensive rat
Barrientos G, Pussetto M, Rose M, Staff A, Blois S, Toblli J
MOL HUM REPROD. 2017;23(7):509-519.

NK cell-derived IL-10 is critical for DC-NK cell dialogue at the maternal-fetal interface
Blois S, Freitag N, Tirado-González I, Cheng S, Heimesaat M, Bereswill S, Rose M, Conrad M, Barrientos G, Sharma S
SCI REP-UK. 2017;7(1):2189.

Endogenous lysophosphatidic acid participates in vascularisation and decidualisation at the maternal-fetal interface in the rat
Sordelli M, Beltrame J, Zotta E, Gomez N, Dmytrenko G, Sales M, Blois S, Davio C, Martinez S, Franchi A, Ribeiro M
REPROD FERT DEVELOP. 2017;29(11):2112-2126.

Evidence for Differential Glycosylation of Trophoblast Cell Types
Chen Q, Pang P, Cohen M, Longtine M, Schust D, Haslam S, Blois S, Dell A, Clark G
MOL CELL PROTEOMICS. 2016;15(6):1857-1866.

Differential Spatiotemporal Patterns of Galectin Expression are a Hallmark of Endotheliochorial Placentation
Conrad M, Freitag N, Diessler M, Hernandez R, Barrientos G, Rose M, Casas L, Barbeito C, Blois S
AM J REPROD IMMUNOL. 2016;75(3):317-325.

Elevated systemic galectin-1 levels characterize HELLP syndrome
Schnabel A, Blois S, Meint P, Freitag N, Ernst W, Barrientos G, Conrad M, Rose M, Seelbach-Göbel B
J REPROD IMMUNOL. 2016;114:38-43.

Leptin promotes HLA-G expression on placental trophoblasts via the MEK/Erk and PI3K signaling pathways
Barrientos G, Toro A, Moschansky P, Cohen M, Garcia M, Rose M, Maskin B, Sánchez-Margalet V, Blois S, Varone C
PLACENTA. 2015;36(4):419-426.

Galectins in angiogenesis: consequences for gestation
Blois S, Conrad M, Freitag N, Barrientos G
J REPROD IMMUNOL. 2015;108:33-41.

A potential pathophysiological role for galectins and the renin-angiotensin system in preeclampsia
Blois S, Dechend R, Barrientos G, Staff A
CELL MOL LIFE SCI. 2015;72(1):39-50.

Involvement of galectin-1 in reproduction: past, present and future
Barrientos G, Freitag N, Tirado-González I, Unverdorben L, Jeschke U, Thijssen V, Blois S
HUM REPROD UPDATE. 2014;20(2):175-193.

Galectin signature in normal pregnancy and preeclampsia
Blois S, Barrientos G
J REPROD IMMUNOL. 2014;101-102:127-134.

Getting too sweet: galectin-1 dysregulation in gestational diabetes mellitus
Blois S, Gueuvoghlanian-Silva B, Tirado-González I, Torloni M, Freitag N, Mattar R, Conrad M, Unverdorben L, Barrientos G, Knabl J, Toldi G, Molvarec A, Rose M, Markert U, Jeschke U, Daher S
MOL HUM REPROD. 2014;20(7):644-649.

Dendritic cells regulate angiogenesis associated with liver fibrogenesis
Blois S, Piccioni F, Freitag N, Tirado-González I, Moschansky P, Lloyd R, Hensel-Wiegel K, Rose M, Garcia M, Alaniz L, Mazzolini G
ANGIOGENESIS. 2014;17(1):119-128.

Pregnancy-specific glycoprotein 1 (PSG1) activates TGF-β and prevents dextran sodium sulfate (DSS)-induced colitis in mice
Blois S, Sulkowski G, Tirado-González I, Warren J, Freitag N, Klapp B, Rifkin D, Fuss I, Strober W, Dveksler G
MUCOSAL IMMUNOL. 2014;7(2):348-158.

Balanced levels of nerve growth factor are required for normal pregnancy progression
Frank P, Barrientos G, Tirado-González I, Cohen M, Moschansky P, Peters E, Klapp B, Rose M, Tometten M, Blois S
REPRODUCTION. 2014;148(2):179-189.

Influence of relative NK-DC abundance on placentation and its relation to epigenetic programming in the offspring
Freitag N, Zwier M, Barrientos G, Tirado-González I, Conrad M, Rose M, Scherjon S, Plösch T, Blois S
CELL DEATH DIS. 2014;5(8):e1392.

Differential immunoregulation in successful oocyte donation pregnancies compared with naturally conceived pregnancies
van der Hoorn M, van Egmond A, Swings G, van Beelen E, van der Keur C, Tirado-González I, Blois S, Karumanchi S, Bianchi D, Claas F, Scherjon S
J REPROD IMMUNOL. 2014;101-102:96-103.

CXCR4(+) dendritic cells promote angiogenesis during embryo implantation in mice
Barrientos G, Tirado-González I, Freitag N, Kobelt P, Moschansky P, Klapp B, Thijssen V, Blois S
ANGIOGENESIS. 2013;16(2):417-427.

Interfering with Gal-1-mediated angiogenesis contributes to the pathogenesis of preeclampsia
Freitag N, Tirado-González I, Barrientos G, Herse F, Thijssen V, Weedon-Fekjær S, Schulz H, Wallukat G, Klapp B, Nevers T, Sharma S, Staff A, Dechend R, Blois S
P NATL ACAD SCI USA. 2013;110(28):11451-1146.

Profiling Lgals9 splice variant expression at the fetal-maternal interface: implications in normal and pathological human pregnancy
Heusschen R, Freitag N, Tirado-González I, Barrientos G, Moschansky P, Muñoz-Fernández R, Leno-Durán E, Klapp B, Thijssen V, Blois S
BIOL REPROD. 2013;88(1):22.

Cell-intrinsic regulation of murine dendritic cell function and survival by prereceptor amplification of glucocorticoid
Soulier A, Blois S, Sivakumaran S, Fallah-Arani F, Henderson S, Flutter B, Rabbitt E, Stewart P, Lavery G, Bennett C, Curnow S, Chakraverty R
BLOOD. 2013;122(19):3288-3297.

NKG2D blockade inhibits poly(I:C)-triggered fetal loss in wild type but not in IL-10-/- mice
Thaxton J, Nevers T, Lippe E, Blois S, Saito S, Sharma S
J IMMUNOL. 2013;190(7):3639-3647.

Galectin-1 influences trophoblast immune evasion and emerges as a predictive factor for the outcome of pregnancy
Tirado-González I, Freitag N, Barrientos G, Shaikly V, Nagaeva O, Strand M, Kjellberg L, Klapp B, Mincheva-Nilsson L, Cohen M, Blois S
MOL HUM REPROD. 2013;19(1):43-53.

Decidual angiogenesis and placental orientation are altered in mice heterozygous for a dominant loss-of-function Gja1 (connexin43) mutation
Winterhager E, Gellhaus A, Blois S, Hill L, Barr K, Kidder G
BIOL REPROD. 2013;89(5):111.

Early expression of pregnancy-specific glycoprotein 22 (PSG22) by trophoblast cells modulates angiogenesis in mice
Blois S, Tirado-González I, Wu J, Barrientos G, Johnson B, Warren J, Freitag N, Klapp B, Irmak S, Ergun S, Dveskler G
BIOL REPROD. 2012;86(6):191.

Uterine NK cells are critical in shaping DC immunogenic functions compatible with pregnancy progression
Tirado-González I, Barrientos G, Freitag N, Otto T, Thijssen V, Moschansky P, von Kwiatkowski P, Klapp B, Winterhager E, Bauersachs S, Blois S
PLOS ONE. 2012;7(10):e46755.

Decidualization and angiogenesis in early pregnancy: unravelling the functions of DC and NK cells
Blois S, Klapp B, Barrientos G
J REPROD IMMUNOL. 2011;88(2):86-92.

Neutralization of LPS or blockage of TLR4 signaling prevents stress-triggered fetal loss in murine pregnancy.
Friebe A, Douglas A, Solano M, Blois S, Hagen E, Klapp B, Clark D, Arck P
J MOL MED. 2011;89(7):689-699.

Peripheral blood galectin-1-expressing T and natural killer cells in normal pregnancy and preeclampsia
Molvarec A, Blois S, Stenczer B, Toldi G, Tirado-Gonzalez I, Ito M, Shima T, Yoneda S, Vásárhelyi B, Rigó J, Saito S
CLIN IMMUNOL. 2011;139(1):48-56.

Substance P is a key mediator of stress-induced protection from allergic sensitization via modified antigen presentation
Pavlovic S, Liezmann C, Blois S, Joachim R, Kruse J, Romani N, Klapp B, Peters E
J IMMUNOL. 2011;186(2):848-855.

Murine abortion is associated with enhanced hyaluronan expression and abnormal localization at the fetomaternal interface
Cordo-Russo R, Garcia M, Barrientos G, Orsal A, Viola M, Moschansky P, Ringel F, Passi A, Alaniz L, Hajos S, Blois S
PLACENTA. 2009;30(1):88-95.

Administration of interferon-alpha in mice provokes peripheral and central modulation of immune cells, accompanied by behavioral effects
Orsal A, Blois S, Bermpohl D, Schaefer M, Coquery N
NEUROPSYCHOBIOLOGY. 2008;58(3-4):211-22.

Analysis of HLA-G in maternal plasma, follicular fluid, and preimplantation embryos reveal an asymmetric pattern of expression
Shaikly V, Morrison I, Taranissi M, Noble C, Withey A, Cherry R, Blois S, Fernández N
J IMMUNOL. 2008;180(6):4330-7.

A pivotal role for galectin-1 in fetomaternal tolerance
Blois S, Ilarregui J, Tometten M, Garcia M, Orsal A, Cordo-Russo R, Toscano M, Bianco G, Kobelt P, Handjiski B, Tirado I, Markert U, Klapp B, Poirier F, Szekeres-Bartho J, Rabinovich G, Arck P
NAT MED. 2007;13(12):1450-7.

Dendritic cells: key to fetal tolerance?
Blois S, Kammerer U, Alba Soto C, Tometten M, Shaikly V, Barrientos G, Jurd R, Rukavina D, Thomson A, Klapp B, Fernández N, Arck P
BIOL REPROD. 2007;77(4):590-8.

An impaired breeding phenotype in mice with a genetic deletion of beta-2 microglobulin and diminished MHC class I expression: role in reproductive fitness
Cooper J, Dealtry G, Ahmed M, Arck P, Klapp B, Blois S, Fernández N
BIOL REPROD. 2007;77(2):274-9.

High expression of survivin and down-regulation of Stat-3 characterize the feto-maternal interface in failing murine pregnancies during the implantation period
Garcia M, Tirado-Gonzalez I, Handjiski B, Tometten M, Orsal A, Hajos S, Fernández N, Arck P, Blois S
PLACENTA. 2007;28(7):650-7.

Antigen-presenting cells and materno-fetal tolerance: an emerging role for dendritic cells
Laskarin G, Kämmerer U, Rukavina D, Thomson A, Fernandez N, Blois S
AM J REPROD IMMUNOL. 2007;58(3):255-67.

Neuroendocrine-immune disequilibrium and endometriosis: an interdisciplinary approach
Tariverdian N, Theoharides T, Siedentopf F, Gutiérrez G, Jeschke U, Rabinovich G, Blois S, Arck P
SEMIN IMMUNOPATHOL. 2007;29(2):193-210.

Dendritic cells therapy confers a protective microenvironment in murine pregnancy
Miranda S, Litwin S, Barrientos G, Szereday L, Chuluyan E, Bartho J, Arck P, Blois S
SCAND J IMMUNOL. 2006;64(5):493-9.

The progesterone derivative dydrogesterone down-regulates neurokinin 1 receptor expression on lymphocytes, induces a Th2 skew and exerts hypoalgesic effects in mice
Orsal A, Blois S, Labuz D, Peters E, Schaefer M, Arck P
J MOL MED. 2006;84(2):159-67.

Prenatal stress enhances susceptibility of murine adult offspring toward airway inflammation
Pincus-Knackstedt M, Joachim R, Blois S, Douglas A, Orsal A, Klapp B, Wahn U, Hamelmann E, Arck P
J IMMUNOL. 2006;177(12):8484-92.

Nerve growth factor translates stress response and subsequent murine abortion via adhesion molecule-dependent pathways
Tometten M, Blois S, Kuhlmei A, Stretz A, Klapp B, Arck P
BIOL REPROD. 2006;74(4):674-83.

Intercellular adhesion molecule-1/LFA-1 cross talk is a proximate mediator capable of disrupting immune integration and tolerance mechanism at the feto-maternal interface in murine pregnancies
Blois S, Tometten M, Kandil J, Hagen E, Klapp B, Margni R, Arck P
J IMMUNOL. 2005;174(4):1820-9.

Lineage, maturity, and phenotype of uterine murine dendritic cells throughout gestation indicate a protective role in maintaining pregnancy
Blois S, Alba Soto C, Tometten M, Klapp B, Margni R, Arck P
BIOL REPROD. 2004;70(4):1018-23.

Depletion of CD8+ cells abolishes the pregnancy protective effect of progesterone substitution with dydrogesterone in mice by altering the Th1/Th2 cytokine profile
Blois S, Joachim R, Kandil J, Margni R, Tometten M, Klapp B, Arck P
J IMMUNOL. 2004;172(10):5893-9.

Letzte Aktualisierung aus dem FIS: 02.11.2025 - 00:32 Uhr