Tätigkeitsschwerpunkte
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Humane Immunologie
Publikationen
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Schneider E#, Winzer R#, Rissiek A, .., Magnus T, Fliegert R, Müller CE, Gagliani N, Tolosa E (2021) CD73-mediated adenosine production by CD8 T cell-derived extracellular vesicles constitutes an intrinsic mechanism of immune suppression in humans. Nat Commun. 2021 8;12:5911
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Poch T, Krause J, Casar C, Liwinski T, Glau L, …Huber S, Tolosa E#, Gagliani N#, Schramm C# (2021) Single-cell atlas of hepatic T cells reveals expansion of liver-resident naive-like CD4+ T cells in primary sclerosing cholangitis. J Hepatol; S0168-8278(21)00219-1
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Mohme M, Schliffke S, Maire CL, Runger A, Glau L, … Westphal M, Binder M#, Tolosa E#, Lamszus K# (2018) Immunophenotyping of Newly Diagnosed and Recurrent Glioblastoma Defines Distinct Immune Exhaustion Profiles in Peripheral and Tumor-infiltrating Lymphocytes. Clin Cancer Res; 24(17):4187-200
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Lessel D, Gehbauer C, Bramswig NC, Schluth-Bolard C, Venkataramanappa S, van Gassen KLI,… Agrawal PB, Britsch S, Tolosa E#, Kubisch C# (2018) BCL11B mutations in patients affected by a neurodevelopmental disorder with reduced type 2 innate lymphoid cells. Brain; 141(8):2299-311
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Thom V, Schmid S, Gelderblom M, Hackbusch R, Kolster M, .., Pless O, Bernreuther C, Glatzel M, Wegscheider K, Gerloff C, Magnus T#, Tolosa E# (2016) IL-17 production by CSF lymphocytes as a biomarker for cerebral vasculitis. Neurol Neuroimmunol Neuroinflamm; 3(2):e214.
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Rissiek A, Baumann I, Cuapio A, Mautner A, Kolster M, Arck PC, Dodge-Khatami A, Mittrucker HW, Koch-Nolte F, Haag F, Tolosa E (2015) The expression of CD39 on regulatory T cells is genetically driven and further upregulated at sites of inflammation. J Autoimmun; 58:12-20.
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Stoeckle C, Quecke P, Ruckrich T, Burster T, Reich M, Weber E, Kalbacher H, Driessen C, Melms A, Tolosa E (2012) Cathepsin S dominates autoantigen processing in human thymic dendritic cells. J Autoimmun; 38(4):332-43.
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Feger U#, Tolosa E#, Huang YH, Waschbisch A, Biedermann T, Melms A, Wiendl H (2007) HLA-G expression defines a novel regulatory T-cell subset present in human peripheral blood and sites of inflammation. Blood; 110(2):568-77.
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Tolosa E, Li W, Yasuda Y, … Driessen C, Schnorrer P, Weber E, Stevanovic S, Kurek R, Melms A, Bromme D (2003) Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis. J Clin Invest; 112(4):517-26.
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Tolosa E, King LB, Ashwell JD (1998) Thymocyte glucocorticoid resistance alters positive selection and inhibits autoimmunity and lymphoproliferative disease in MRL-lpr/lpr mice. Immunity; 8(1):67-76.
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#shared authorships