- Wissenschaftlicher Mitarbeiter
- Forschungsgruppenleiter
- Facharzt für Mikrobiologie, Virologie und Infektionsepidemiologie
Tätigkeitsschwerpunkte
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Erforschung der Mechanismen der Immunmodulation durch enteropathogene Yersinien
Publikationen
Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells
Berneking L, Schnapp M, Rumm A, Trasak C, Ruckdeschel K, Alawi M, Grundhoff A, Kikhney A, Nolte F, Buck F, Perbandt M, Betzel C, Svergun D, Hentschke M, Aepfelbacher M
PLOS PATHOG. 2016;12(6):e1005660.
Cell death triggered by Yersinia enterocolitica identifies processing of the proinflammatory signal adapter MyD88 as a general event in the execution of apoptosis
Novikova L, Czymmeck N, Deuretzbacher A, Buck F, Richter K, Weber A, Aepfelbacher M, Ruckdeschel K
J IMMUNOL. 2014;192(3):1209-19.
Cytotoxic necrotizing factor-Y boosts Yersinia effector translocation by activating Rac protein
Wolters M, Boyle C, Lardong K, Trülzsch K, Steffen A, Rottner K, Ruckdeschel K, Aepfelbacher M
J BIOL CHEM. 2013;288(32):23543-53.
Guidelines for the use and interpretation of assays for monitoring autophagy.
Klionsky D, Abdalla F, Abeliovich H, Abraham R, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso J, Ahn H, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes H, Al-Zeer M, Albert M, Albin R, Alegre-Abarrategui J, Aleo M, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer A, Andrieu-Abadie N, Anantharam V, Ann D, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris J, Asanuma K, Asare N, Ashida H, Askanas V, Askew D, Auberger P, Baba M, Backues S, Baehrecke E, Bahr B, Bai X, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber B, Bampton E, Bánhegyi G, Bartholomew C, Bassham D, Bast R, Batoko H, Bay B, Beau I, Béchet D, Begley T, Behl C, Behrends C, Bekri S, Bellaire B, Bendall L, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Besteiro S, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum J, Boise L, Bonaldo P, Boone D, Bornhauser B, Bortoluci K, Bossis I, Bost F, Bourquin J, Boya P, Boyer-Guittaut M, Bozhkov P, Brady N, Brancolini C, Brech A, Brenman J, Brennand A, Bresnick E, Brest P, Bridges D, Bristol M, Brookes P, Brown E, Brumell J, Brunetti-Pierri N, Brunk U, Bulman D, Bultman S, Bultynck G, Burbulla L, Bursch W, Butchar J, Buzgariu W, Bydlowski S, Cadwell K, Cahová M, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan A, Carding S, Cardoso S, Carew J, Carlin C, Carmignac V, Carneiro L, Carra S, Caruso R, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae H, Chai C, Chan D, Chan E, Chang R, Che C, Chen C, Chen G, Chen G, Chen M, Chen Q, Chen S, Chen W, Chen X, Chen X, Chen X, Chen Y, Chen Y, Chen Y, Chen Y, Chen Z, Cheng A, Cheng C, Cheng Y, Cheong H, Cheong J, Cherry S, Chess-Williams R, Cheung Z, Chevet E, Chiang H, Chiarelli R, Chiba T, Chin L, Chiou S, Chisari F, Cho C, Cho D, Choi A, Choi D, Choi K, Choi M, Chouaib S, Choubey D, Choubey V, Chu C, Chuang T, Chueh S, Chun T, Chwae Y, Chye M, Ciarcia R, Ciriolo M, Clague M, Clark R, Clarke P, Clarke R, Codogno P, Coller H, Colombo M, Comincini S, Condello M, Condorelli F, Cookson M, Coombs G, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon F, Cregg J, Crespo J, Cronjé M, Cuervo A, Cullen J, Czaja M, D'Amelio M, Darfeuille-Michaud A, Davids L, Davies F, Massimo D, Groot d, John F, Haan d, Cornelis A, Luisa D, Angelo D, Vincenzo D, Debnath J, Degterev A, Dehay B, Delbridge L, Demarchi F, Deng Y, Dengjel J, Dent P, Denton D, Deretic V, Desai S, Devenish R, Mario D, Gilbert D, Chiara D, Díaz-Araya G, Díaz-Laviada I, Diaz-Meco M, Diaz-Nido J, Dikic I, Dinesh-Kumar S, Ding W, Dis [, Ruckdeschel K
AUTOPHAGY. 2012;8(4):445-544.
Activity modulation of the bacterial Rho GAP YopE: an inspiration for the investigation of mammalian Rho GAPs.
Aepfelbacher M, Roppenser B, Hentschke M, Ruckdeschel K
EUR J CELL BIOL. 2011;90(11):951-954.
Destabilization of YopE by the Ubiquitin-Proteasome Pathway Fine-Tunes Yop Delivery into Host Cells and Facilitates Systemic Spread of Yersinia enterocolitica in Host Lymphoid Tissue.
Gaus K, Hentschke M, Czymmeck N, Novikova L, Trülzsch K, Valentin-Weigand P, Aepfelbacher M, Ruckdeschel K
INFECT IMMUN. 2011;79(3):1166-1175.
Staphylococcus epidermidis uses distinct mechanisms of biofilm formation to interfere with phagocytosis and activation of mouse macrophage-like cells 774A.1.
Schommer N, Christner M, Hentschke M, Ruckdeschel K, Aepfelbacher M, Rohde H
INFECT IMMUN. 2011;79(6):2267-2276.
Yersinia virulence factor YopM induces sustained RSK activation by interfering with dephosphorylation.
Hentschke M, Berneking L, Campos C, Buck F, Ruckdeschel K, Aepfelbacher M
PLOS ONE. 2010;5(10):.
Beta1 integrin-dependent engulfment of Yersinia enterocolitica by macrophages is coupled to the activation of autophagy and suppressed by type III protein secretion.
Deuretzbacher A, Czymmeck N, Reimer R, Trülzsch K, Gaus K, Hohenberg H, Heesemann J, Aepfelbacher M, Ruckdeschel K
J IMMUNOL. 2009;183(9):5847-5860.
Yersinia enterocolitica differentially modulates RhoG activity in host cells.
Roppenser B, Röder A, Hentschke M, Ruckdeschel K, Aepfelbacher M
J CELL SCI. 2009;122(5):696-705.
Crosstalk of signalling processes of innate immunity with Yersinia Yop effector functions.
Ruckdeschel K, Deuretzbacher A, Haase R
IMMUNOBIOLOGY. 2008;213(3-4):261-269.
If the rumor is tumor, the issue is tissue.
Wichmann D, Scherpe S, Heese O, Schmiedel S, Burchard G, Ruckdeschel K, Sobottka I
NEUROSURGERY. 2008;63(4):820.
Effector functions of pathogenic Yersinia species.
Aepfelbacher M, Trasak C, Ruckdeschel K
THROMB HAEMOSTASIS. 2007;98(3):521-529.
Yersinia enterocolitica YopP inhibits MAP kinase-mediated antigen uptake in dendritic cells.
Autenrieth S, Soldanova I, Rösemann R, Gunst D, Zahir N, Kracht M, Ruckdeschel K, Wagner H, Borgmann S, Autenrieth I
CELL MICROBIOL. 2007;9(2):425-437.
Catalytically active Yersinia outer protein P induces cleavage of RIP and caspase-8 at the level of the DISC independently of death receptors in dendritic cells.
Gröbner S, Adkins I, Schulz S, Richter K, Borgmann S, Wesselborg S, Ruckdeschel K, Micheau O, Autenrieth I
APOPTOSIS. 2007;12(10):1813-1825.
Letzte Aktualisierung aus dem FIS: 17.07.2017 - 00:04 Uhr