Lepu Zhou
Dr. med.
Lepu Zhou
  • Wissenschaftler
Arbeitsbereich

Standort

N61 , 3. Etage, Raumnummer 305.2
Sprachen
Chinesisch (Muttersprache)
Deutsch
Englisch

Tätigkeitsschwerpunkte

Publikationen

2018

Neurodegeneration and NLRP3 inflammasome expression in the anterior thalamus of SOD1(G93A) ALS mice
Debye B, Schmülling L, Zhou L, Rune G, Beyer C, Johann S
BRAIN PATHOL. 2018;28(1):14-27.

Reelin and aromatase cooperate in ovarian follicle development
Meseke M, Pröls F, Schmahl C, Seebo K, Kruse C, Brandt N, Fester L, Zhou L, Bender R, Rune G
SCI REP-UK. 2018;8(1):8722.

2017

Sex-dependent regulation of aromatase-mediated synaptic plasticity in the basolateral amygdala
Bender R, Zhou L, Vierk R, Brandt N, Keller A, Gee C, Schäfer M, Rune G
J NEUROSCI. 2017;37(6):1532-1545.

Synaptopodin is regulated by aromatase activity
Fester L, Zhou L, Ossig C, Labitzke J, Bläute C, Bader M, Vollmer G, Jarry H, Rune G
J NEUROCHEM. 2017;140(1):126-139.

The serine protease inhibitor neuroserpin is required for normal synaptic plasticity and regulates learning and social behavior
Reumann R, Vierk R, Zhou L, Gries F, Kraus V, Mienert J, Romswinkel E, Morellini F, Ferrer I, Nicolini C, Fahnestock M, Rune G, Glatzel M, Galliciotti G
LEARN MEMORY. 2017;24(12):650-659.

2014

Geschlecht und Effekte von Steroidhormonen im Zentralnervensystem (ZNS)
Brandt N, Vierk R, Fester L, Zhou L, Imholz P, Rune G
BUNDESGESUNDHEITSBLATT. 2014;57(9):1054-60.

Oestradiol-induced synapse formation in the female hippocampus: roles of oestrogen receptor subtypes
Zhou L, Fester L, Haghshenas S, de Vrese X, von Hacht R, Gloger S, Brandt N, Bader M, Vollmer G, Rune G
J NEUROENDOCRINOL. 2014;26(7):439-47.

2013

Endocrine regulation of estrogen synthesis in the hippocampus?
Prange-Kiel J, Schmutterer T, Fester L, Zhou L, Imholz P, Brandt N, Vierk R, Jarry H, Rune G
PROG HISTOCHEM CYTO. 2013;48(2):49-64.

2012

Estrogen-regulated synaptogenesis in the hippocampus: sexual dimorphism in vivo but not in vitro.
Fester L, Prange-Kiel J, Zhou L, von Blittersdorf B, Böhm J, Jarry H, Schumacher M, Rune G
J STEROID BIOCHEM. 2012;131(1-2):24-29.

Aromatase inhibition abolishes LTP generation in female but not in male mice.
Vierk R, Glassmeier G, Zhou L, Brandt N, Fester L, Dudzinski D, Wilkars W, Bender R, Lewerenz M, Gloger S, Graser L, Schwarz J, Rune G
J NEUROSCI. 2012;32(24):8116-8126.

2011

Tau-induced defects in synaptic plasticity, learning, and memory are reversible in transgenic mice after switching off the toxic Tau mutant.
Sydow A, Ann V, Zheng F, Ahmed T, Balschun D, Petrova O, Drexler D, Zhou L, Rune G, Mandelkow E, Alzheimer C, Mandelkow E
J NEUROSCI. 2011;31(7):2511-2525.

Reversibility of Tau-related cognitive defects in a regulatable FTD mouse model.
Sydow A, Ann V, Zheng F, Ahmed T, Balschun D, Petrova O, Drexler D, Zhou L, Rune G, Mandelkow E, D'Hooge R, Alzheimer C, Mandelkow E
J MOL NEUROSCI. 2011;45(3):432-437.

2010

Roles of 17ß-estradiol involve regulation of reelin expression and synaptogenesis in the dentate gyrus.
Bender R, Zhou L, Wilkars W, Fester L, Lanowski J, Paysen D, König A, Rune G
CEREB CORTEX. 2010;20(12):2985-2995.

Aromatase inhibitors induce spine synapse loss in the hippocampus of ovariectomized mice.
Zhou L, Fester L, von Blittersdorf B, Hassu B, Nogens H, Prange-Kiel J, Jarry H, Wegscheider K, Rune G
ENDOCRINOLOGY. 2010;151(3):1153-1160.

2009

Cholesterol-promoted synaptogenesis requires the conversion of cholesterol to estradiol in the hippocampus.
Fester L, Zhou L, Bütow A, Huber C, von Lossow R, Prange-Kiel J, Jarry H, Rune G
HIPPOCAMPUS. 2009.

The opposing roles of estradiol on synaptic protein expression in hippocampal cultures.
Fester L, Zhou L, Voets C, Ossig C, Disteldorf E, Peters C, Bläute F, Prange-Kiel J, Dudzinski D, Jarry H, Rune G
PSYCHONEUROENDOCRINO. 2009;34(1):123-129.

Estrus cyclicity of spinogenesis: underlying mechanisms.
Prange-Kiel J, Fester L, Zhou L, Jarry H, Rune G
J NEURAL TRANSM. 2009;116(11):1417-1425.

2008

The potential for beta-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy.
Mocanu M, Nissen A, Eckermann K, Khlistunova I, Biernat J, Drexler D, Petrova O, Schönig K, Bujard H, Mandelkow E, Zhou L, Rune G, Mandelkow E
J NEUROSCI. 2008;28(3):737-748.

Gonadotropin-releasing hormone regulates spine density via its regulatory role in hippocampal estrogen synthesis.
Prange-Kiel J, Jarry H, Schoen M, Kohlmann P, Lohse C, Zhou L, Rune G
J CELL BIOL. 2008;180(2):417-426.

2007

The beta-propensity of Tau determines aggregation and synaptic loss in inducible mouse models of tauopathy.
Eckermann K, Mocanu M, Khlistunova I, Biernat J, Nissen A, Hofmann A, Schönig K, Bujard H, Haemisch A, Mandelkow E, Zhou L, Rune G, Mandelkow E
J BIOL CHEM. 2007;282(43):31755-31765.

Neuroprotection by estradiol: a role of aromatase against spine synapse loss after blockade of GABA(A) receptors.
Zhou L, Lehan N, Wehrenberg U, Disteldorf E, von Lossow R, Mares U, Jarry H, Rune G
EXP NEUROL. 2007;203(1):72-81.

2006

Inhibition of hippocampal estrogen synthesis causes region-specific downregulation of synaptic protein expression in hippocampal neurons.
Prange-Kiel J, Fester L, Zhou L, Lauke H, Carrétero J, Rune G
HIPPOCAMPUS. 2006;16(5):464-471.

2004

Hippocampal synapses depend on hippocampal estrogen synthesis.
Kretz O, Fester L, Wehrenberg U, Zhou L, Brauckmann S, Zhao S, Prange-Kiel J, Naumann T, Jarry H, Frotscher M, Rune G
J NEUROSCI. 2004;24(26):5913-5921.

1996

Expression of ciliary neurotrophic factor is maintained in spinal motor neurons of amyotrophic lateral sclerosis
Schorr M, Zhou L, Schwechheimer K
J NEUROL SCI. 1996;140(1-2):117-22.

Letzte Aktualisierung aus dem FIS: 15.12.2019 - 00:37 Uhr