Staff

Principal Investigators
Prof. Dr. med. Walter Fiedler fiedler@uke.uni-hamburg.de
Dr. rer. nat. Jasmin Wellbrock j.wellbrock@uke.de

Nader Attar (Medizin-Doktorand)
Dr. Lena Behrmann (Postdoc)
Franziska Braueck (Ärztin)
Fabian Freisleben (Medizin-Doktorand)
Frauke Fuchs (naturwissenschaftliche Doktorandin)
Zoran Kneszevic (naturwissenschaftlicher Doktorand)
Alexander Krispien (Medizin-Doktorand)
Dr. Franziska Modemann (Ärztin)
Jana Muschhammer (BTA)
Leonie Ramke (Medizin-Doktorandin)
Vanessa Thaden (BTA)
Gabi Vohwinkel (MTA)
Ella Walz (TA-Praktikantin)

Interested in our research? We offer research projects to all interested and dedicated students for their master thesis or medical doctoral thesis. If you are interested, please contact: j.wellbrock@uke.de.

Research focus

Leukemic stem cells reside within the bone marrow niche which provides a protected environment resulting in resistance to chemotherapy. The complex interactions between leukemic and stromal cells within the niche are not yet fully understood. Our research focuses on the identification of those complex interaction networks which may provide novel approaches of targeted therapies for leukemia patients. Our main research focus concentrates on acute myeloid leukemia. We have access to bone marrow and peripheral blood samples of AML patients which are collected in an AML biobank at our department. Furthermore, we are members of one of the leading German AML study groups allowing direct correlation of our research findings to clinical data. We often work in close collaboration with the pharmaceutical industry.
Our ongoing research projects concentrate on stem cell signalling pathways being relevant for the leukemic stem cell niche, the influence of a hypoxic microenvironment in the bone marrow and novel aspects of immune therapies for the treatment of AML patients.

Cooperation partners

• Prof. Dr. Manfred Jücker, Dr. Sabine Windhorst, Department of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
• Prof. Dr. Boris Fehse, Dr. Kerstin Cornils, Dr. Stefan Horn, Dr. Kristoffer Rieken, Department of Stem Cell Transplantation, Research Department Cell and Gene Therapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
• Prof. Dr. Nicolaus Kröger, Dr. Max Christopeit, Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
• Prof. Dr. Tobias Lange, Dr. Daniel Wicklein, Institute of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
• Dr. Malte Schröder, Dr. Lennart Viezens, Trauma and Reconstructive Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
• Dr. Leticia Oliveira-Ferrer, Department of Gynecology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
• Prof. Dr. Yskert von Kodolitsch, Center of Cardiology and Cardiovascular Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
• Dr. Andrea Horst, Institute of Experimental Immunology and Hematology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
• Dr. Carol Stocking, Retroviral Pathogenesis, Heinrich-Pette-Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany
• Prof. Dr. Martin Horstmann, Research Institute Children's Cancer Center and Clinic of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
• Dr. Michael Heuser, Dr. Felicitas Thol, Medical School Hannover, Hannover, Germany · Dr. Lars Bullinger, University Medical Center Ulm, Ulm, Germany
• Dr. Thomas Oellerich, University Medical Center Frankfurt, Frankfurt, Germany
• Dr. César Nombela Arrieta, Division of Experimental Hematology, University Hospital Zurich, University of Zurich, Zurich, Switzerland
• Dr. Cedric dos Santos, Amgen, Thousand Oaks, USA
• Dr. Marie O´Farrell, 3.V Biosciences, Menlo Park, USA
• Dr. Diego Alvarado, Kolltan Pharmaceuticals, New Haven, USA
• Dr. Eric Campeau, Zenith Epigenetics, Calgary, Canada
• Dr. Vadim Sumbayev, Prof. Dr. Yuri Ushkaryov, Medway School of Pharmacy, University of Kent, UK

Contact information

Acute Leukemia Group

Department of Oncology, Haematology and Bone Marrow Transplantation with section Pneumology

Campus Forschung (N27), 4th floor, rooms 077/078/091

University Medical Center Hamburg-Eppendorf
Martinistr. 52
D-20246 Hamburg

Telephone: 040/7410-55606 (office), -55031 und -55931 (lab)
Telefax: 040/7410-55896