2025

Underlying biology, challenges and emergent concepts in the treatment of relapsed and refractory pediatric T-cell acute lymphoblastic leukemia
Amaral P, Christie R, Gresham D, Lucas E, Xu L, Behrmann L, Bond J, Degerman S, Delft F, Goossens S, Hagleitner M, Halsey C, Jones N, Lammens T, Leeuwen F, Mansour M, Ntziachristos P, O’Connor D, Barata J
LEUKEMIA. 2025.

A case report of a pediatric T-cell acute lymphoblastic leukemia with a subclonal GCC2::PDGFRB t(2;5) translocation - implementation for the selection of MRD-targets
Monsees E, Hauch R, Wrzeszcz A, Spohn M, Strauss J, Zur Stadt U, Horstmann M, Escherich G, Behrmann L
LEUKEMIA LYMPHOMA. 2025;66(8):1526-1530.

Characterization of a PRKCE::ETV6 fusion as a potential oncogenic driver in T-cell acute lymphoblastic leukemia.
Monsees E, Zur S, Strauss J, Schuster S, Kleist N, Hauch R, Spohn M, Wolters-Eisfeld G, Horstmann M, Escherich G, Behrmann L
MOL CELL PEDIATR. 2025;12(1):16.

2024

Murine Regulatory CD4+ T Cells Are Increased in Leukemic Spleens and Show High Co-Expression of Co-Regulatory Molecules CD39, CD73, PD1, and TIGIT
Krüger J, Wellbrock J, Witt M, Kruppa N, Muschhammer J, Bokemeyer C, Modemann F, Fiedler W, Behrmann L, Brauneck F
INT J MOL SCI. 2024;25(21):.

Pediatric T-cell lymphoblastic lymphomas but not leukemias harbor TRB::NOTCH1 fusions with unfavorable outcome
Te Vrugt M, Wessolowski J, Randau G, Alfert A, Mueller S, Scholten K, Sopalla C, Lanvers-Kaminsky C, Hotfilder M, Lamp F, Damm-Welk C, Luedersen J, Escherich G, Zur Stadt U, Behrmann L, Woessmann W, Oschlies I, Marzi M, Zimmermann M, Burkhardt B
BLOOD. 2024;144(13):1412-1417.

2021

The BET bromodomain inhibitor ZEN-3365 targets the Hedgehog signaling pathway in acute myeloid leukemia
Wellbrock J, Behrmann L, Muschhammer J, Modemann F, Khoury K, Brauneck F, Bokemeyer C, Campeau E, Fiedler W
ANN HEMATOL. 2021;100(12):2933-2941.

2020

The bone marrow stromal niche: a therapeutic target of hematological myeloid malignancies
Behrmann L, Wellbrock J, Fiedler W
EXPERT OPIN THER TAR. 2020;24(5):451-462.

Downregulation of GLI3 Expression Mediates Chemotherapy Resistance in Acute Myeloid Leukemia
Freisleben F, Behrmann L, Thaden V, Muschhammer J, Bokemeyer C, Fiedler W, Wellbrock J
INT J MOL SCI. 2020;21(14):.

2018

Acute Myeloid Leukemia and the Bone Marrow Niche-Take a Closer Look
Behrmann L, Wellbrock J, Fiedler W
FRONT ONCOL. 2018;8:444.

Combined inhibition of receptor tyrosine and p21-activated kinases as a therapeutic strategy in childhood ALL
Siekmann I, Dierck K, Prall S, Klokow M, Strauss J, Buhs S, Wrzeszcz A, Bockmayr M, Beck F, Trochimiuk M, Gottschling K, Martens V, Khosh-Naucke M, Gerull H, Müller J, Behrmann L, Blohm M, Zahedi R, Jeremias I, Sickmann A, Nollau P, Horstmann M
BLOOD ADV. 2018;2(19):2554-2567.

Letzte Aktualisierung aus dem FIS: 11.01.2026 - 07:05 Uhr