Welcome to the Institute for Infection Research and Vaccine Development - IIRVD

The Institute for Infection Research and Vaccine Development at the Center for Internal Medicine of the University Medical Center Hamburg-Eppendorf (UKE) was founded in January 2022 under the leadership of Director Marylyn M. Addo .

The scientific focus of the institute is basic and translational infection and vaccine research . The interdisciplinary scientific team's research includes new and re-emerging viruses, such as Ebola and coronaviruses – such as SARS-CoV-2 and the Middle East Respiratory Syndrome coronavirus (MERS-CoV). Other viruses such as hepatitis B may also be the focus of research.

One focus of research is the study of immunity to viruses and vaccines, including analysis of sex differences (DFG Research Unit 5068 ). In addition, early safety and efficacy studies of vaccines, as well as treatment and observational studies in the field of infectious dieseases are are conducted at the Institute.

Two BMBF-funded Clinician-Scientist junior research groups are affiliated with the Institute for Infection Research and Vaccine Development: The junior research group "Genomics of Retroviral Infections" headed by PD Dr. Dr. Ulrike Lange at LIV (formerly HPI) and the research group "Infection & Immune Regulation" headed by Dr. Dr. Angelique Hölzemer MD/PhD at the I. Medical Clinic of the Center for Internal Medicine and the Institute for Infection Research and Vaccine Development.


The latest publications, prices and events of the IIRVD.

Our interdisciplinary team

Our interdisciplinary team consists of scientists, clinicians, technical assistance.

Our research partners and funding sources

Our research is funded by national and international institutions.

Clinical trials

We initiate and coordinate translational clinical trials, including immunological studies, vaccine development and testing of novel anti-infectives.

Research at the institute

Our research aims to investigate and develop vaccine strategies for infections with emerging viruses.


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You can find images in the download area of the Press office .