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A fetal wave of human type 3 effector γδ cells with restricted TCR diversity persists into adulthood
Tan L, Fichtner A, Bruni E, Odak I, Sandrock I, Bubke A, Borchers A, Schultze-Florey C, Koenecke C, Förster R, Jarek M, von Kaisenberg C, Schulz A, Chu X, Zhang B, Li Y, Panzer U, Krebs C, Ravens S, Prinz I
Sci Immunol. 2021;6(58):.

Influenza A virus-induced thymus atrophy differentially affects dynamics of conventional and regulatory T cell development in mice
Elfaki Y, Robert P, Binz C, Falk C, Bruder D, Prinz I, Floess S, Meyer-Hermann M, Huehn J
EUR J IMMUNOL. 2021;51(5):1166-1181.

Maturation of the neonatal oral mucosa involves unique epithelium-microbiota interactions
Koren N, Zubeidat K, Saba Y, Horev Y, Barel O, Wilharm A, Heyman O, Wald S, Eli-Berchoer L, Shapiro H, Nadler C, Elinav E, Wilensky A, Prinz I, Bercovier H, Hovav A
CELL HOST MICROBE. 2021;29(2):197-209.e5.

IL-17 controls central nervous system autoimmunity through the intestinal microbiome
Regen T, Isaac S, Amorim A, Núñez N, Hauptmann J, Shanmugavadivu A, Klein M, Sankowski R, Mufazalov I, Yogev N, Huppert J, Wanke F, Witting M, Grill A, Gálvez E, Nikolaev A, Blanfeld M, Prinz I, Schmitt-Kopplin P, Strowig T, Reinhardt C, Prinz M, Bopp T, Becher B, Ubeda C, Waisman A
Sci Immunol. 2021;6(56):.

Peritoneal dialysate-range hypertonic glucose promotes T-cell IL-17 production that induces mesothelial inflammation
Helmke A, Hüsing A, Gaedcke S, Brauns N, Balzer M, Reinhardt M, Hiss M, Shushakova N, de Luca D, Prinz I, Haller H, von Vietinghoff S
EUR J IMMUNOL. 2021;51(2):354-367.

γδT Cells Are Essential for Orthodontic Tooth Movement
Wald S, Leibowitz A, Aizenbud Y, Saba Y, Zubeidat K, Barel O, Koren N, Heyman O, Wilharm A, Sandrock I, Fleissig O, Tal Y, Prinz I, Aizenbud D, Chaushu S, Hovav A
J DENT RES. 2021;22034520984774.

Correction: Microbiota-dependent expansion of testicular IL-17-producing Vγ6+ γδ T cells upon puberty promotes local tissue immune surveillance
Wilharm A, Brigas H, Sandrock I, Ribeiro M, Amado T, Reinhardt A, Demera A, Hoenicke L, Strowig T, Carvalho T, Prinz I, Ribot J
Mucosal Immunol. 2021;14(1):278.

Microbiota-dependent expansion of testicular IL-17-producing Vγ6+ γδ T cells upon puberty promotes local tissue immune surveillance
Wilharm A, Brigas H, Sandrock I, Ribeiro M, Amado T, Reinhardt A, Demera A, Hoenicke L, Strowig T, Carvalho T, Prinz I, Ribot J
Mucosal Immunol. 2021;14(1):242-252.

Synthetic retinoid AM80 inhibits IL-17 production of gamma delta T cells and ameliorates biliary atresia in mice
Möhn N, Bruni E, Schröder A, Frömmel S, Gueler F, Vieten G, Prinz I, Kuebler J, Petersen C, Klemann C
LIVER INT. 2020;40(12):3031-3041.

From basic research to clinical application of γδ T cells
Déchanet-Merville J, Prinz I
Immunological reviews. 2020;298(1):5-9.

Ligand recognition by the γδ TCR and discrimination between homeostasis and stress conditions
Deseke M, Prinz I
CELL MOL IMMUNOL. 2020;17(9):914-924.

PD-L1 Checkpoint Inhibition Narrows the Antigen-Specific T Cell Receptor Repertoire in Chronic Lymphocytic Choriomeningitis Virus Infection
Klein S, Ghersi D, Manns M, Prinz I, Cornberg M, Kraft A
J VIROL. 2020;94(18):.

Microbial exposure drives polyclonal expansion of innate γδ T cells immediately after birth
Ravens S, Fichtner A, Willers M, Torkornoo D, Pirr S, Schöning J, Deseke M, Sandrock I, Bubke A, Wilharm A, Dodoo D, Egyir B, Flanagan K, Steinbrück L, Dickinson P, Ghazal P, Adu B, Viemann D, Prinz I
P NATL ACAD SCI USA. 2020;117(31):18649-18660.

IL-17 regulates DC migration to the peribronchial LNs and allergen presentation in experimental allergic asthma
Jirmo A, Busse M, Happle C, Skuljec J, Dalüge K, Habener A, Grychtol R, DeLuca D, Breiholz O, Prinz I, Hansen G
EUR J IMMUNOL. 2020;50(7):1019-1033.

Reappearance of effector T cells is associated with recovery from COVID-19
Odak I, Barros-Martins J, Bošnjak B, Stahl K, David S, Wiesner O, Busch M, Hoeper M, Pink I, Welte T, Cornberg M, Stoll M, Goudeva L, Blasczyk R, Ganser A, Prinz I, Förster R, Koenecke C, Schultze-Florey C
EBioMedicine. 2020;57:102885.

TCR repertoire analysis reveals phosphoantigen-induced polyclonal proliferation of Vγ9Vδ2 T cells in neonates and adults
Fichtner A, Bubke A, Rampoldi F, Tan L, Wilharm A, Steinbrück L, Schultze-Florey C, von Kaisenberg C, Prinz I, Herrmann T, Ravens S
J LEUKOCYTE BIOL. 2020;107(6):1023-1032.

Development and Function of γδT Cells in the Oral Mucosa
Hovav A, Wilharm A, Barel O, Prinz I
J DENT RES. 2020;99(5):498-505.

Regulatory T Cells Limit Pneumococcus-Induced Exacerbation of Lung Fibrosis in Mice
Moyé S, Bormann T, Maus R, Sparwasser T, Sandrock I, Prinz I, Warnecke G, Welte T, Gauldie J, Kolb M, Maus U
J IMMUNOL. 2020;204(9):2429-2438.

γδ T-cell Receptors Derived from Breast Cancer-Infiltrating T Lymphocytes Mediate Antitumor Reactivity
Janssen A, Villacorta Hidalgo J, Beringer D, van Dooremalen S, Fernando F, van Diest E, Terrizi A, Bronsert P, Kock S, Schmitt-Gräff A, Werner M, Heise K, Follo M, Straetemans T, Sebestyen Z, Chudakov D, Kasatskaya S, Frenkel F, Ravens S, Spierings E, Prinz I, Küppers R, Malkovsky M, Fisch P, Kuball J
Cancer Immunol Res. 2020;8(4):530-543.

Human γδ TCR Repertoires in Health and Disease
Fichtner A, Ravens S, Prinz I
CELLS-BASEL. 2020;9(4):.

Revisiting the Interaction of γδ T-Cells and B-Cells
Rampoldi F, Ullrich L, Prinz I
CELLS-BASEL. 2020;9(3):.

Translating gammadelta (γδ) T cells and their receptors into cancer cell therapies
Sebestyen Z, Prinz I, Déchanet-Merville J, Silva-Santos B, Kuball J
NAT REV DRUG DISCOV. 2020;19(3):169-184.

Interleukin-17 cytokines: Effectors and targets in psoriasis-A breakthrough in understanding and treatment
Prinz I, Sandrock I, Mrowietz U
J EXP MED. 2020;217(1):.

Donor-derived IL-17A and IL-17F deficiency triggers Th1 allo-responses and increases gut leakage during acute GVHD
Odak I, Depkat-Jakob A, Beck M, Jarek M, Yu Y, Seidler U, David S, Ganser A, Förster R, Prinz I, Koenecke C
PLOS ONE. 2020;15(4):e0231222.

NKp46-expressing human gut-resident intraepithelial Vδ1 T cell subpopulation exhibits high antitumor activity against colorectal cancer
Mikulak J, Oriolo F, Bruni E, Roberto A, Colombo F, Villa A, Bosticardo M, Bortolomai I, Lo Presti E, Meraviglia S, Dieli F, Vetrano S, Danese S, Della Bella S, Carvello M, Sacchi M, Cugini G, Colombo G, Klinger M, Spaggiari P, Roncalli M, Prinz I, Ravens S, di Lorenzo B, Marcenaro E, Silva-Santos B, Spinelli A, Mavilio D
JCI Insight. 2019;4(24):.

Focusing of the regulatory T-cell repertoire after allogeneic stem cell transplantation indicates protection from graft-versus-host disease
Odak I, Raha S, Schultze-Florey C, Tavil S, Ravens S, Ganser A, Förster R, Prinz I, Koenecke C
HAEMATOLOGICA. 2019;104(12):e577-e580.

Dangerous γδ T cells in aged mice
Prinz I, Sandrock I
EMBO REP. 2019;20(8):e48678.

Styk1 is specifically expressed in NK1.1+ lymphocytes including NK, γδ T, and iNKT cells in mice, but is dispensable for their ontogeny and function
Wilharm A, Sandrock I, Marotel M, Demera A, Naumann R, Walzer T, Prinz I
EUR J IMMUNOL. 2019;49(5):686-693.

Broad Cytotoxic Targeting of Acute Myeloid Leukemia by Polyclonal Delta One T Cells
Di Lorenzo B, Simões A, Caiado F, Tieppo P, Correia D, Carvalho T, da Silva M, Déchanet-Merville J, Schumacher T, Prinz I, Norell H, Ravens S, Vermijlen D, Silva-Santos B
Cancer Immunol Res. 2019;7(4):552-558.

Robust Identification of Suitable T-Cell Subsets for Personalized CMV-Specific T-Cell Immunotherapy Using CD45RA and CD62L Microbeads
Mangare C, Tischer-Zimmermann S, Riese S, Dragon A, Prinz I, Blasczyk R, Maecker-Kolhoff B, Eiz-Vesper B
INT J MOL SCI. 2019;20(6):.

Germ Line Deletion Reveals a Nonessential Role of Atypical Mitogen-Activated Protein Kinase 6/Extracellular Signal-Regulated Kinase 3
Ronkina N, Schuster-Gossler K, Hansmann F, Kunze-Schumacher H, Sandrock I, Yakovleva T, Lafera J, Baumgärtner W, Krueger A, Prinz I, Gossler A, Kotlyarov A, Gaestel M
MOL CELL BIOL. 2019;39(6):.

The Skin Commensal Yeast Malassezia Triggers a Type 17 Response that Coordinates Anti-fungal Immunity and Exacerbates Skin Inflammation
Sparber F, De Gregorio C, Steckholzer S, Ferreira F, Dolowschiak T, Ruchti F, Kirchner F, Mertens S, Prinz I, Joller N, Buch T, Glatz M, Sallusto F, LeibundGut-Landmann S
CELL HOST MICROBE. 2019;25(3):389-403.e6.

miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity
Łyszkiewicz M, Winter S, Witzlau K, Föhse L, Brownlie R, Puchałka J, Verheyden N, Kunze-Schumacher H, Imelmann E, Blume J, Raha S, Sekiya T, Yoshimura A, Frueh J, Ullrich E, Huehn J, Weiss S, Gutierrez M, Prinz I, Zamoyska R, Ziętara N, Krueger A
PLOS BIOL. 2019;17(3):e2006716.

Mutual interplay between IL-17-producing γδT cells and microbiota orchestrates oral mucosal homeostasis
Wilharm A, Tabib Y, Nassar M, Reinhardt A, Mizraji G, Sandrock I, Heyman O, Barros-Martins J, Aizenbud Y, Khalaileh A, Eli-Berchoer L, Elinav E, Wilensky A, Förster R, Bercovier H, Prinz I, Hovav A
P NATL ACAD SCI USA. 2019;116(7):2652-2661.

Hepatitis E Virus (HEV)-Specific T Cell Receptor Cross-Recognition: Implications for Immunotherapy
Soon C, Zhang S, Suneetha P, Antunes D, Manns M, Raha S, Schultze-Florey C, Prinz I, Wedemeyer H, Sällberg Chen M, Cornberg M
FRONT IMMUNOL. 2019;10:2076.

Letzte Aktualisierung aus dem FIS: 15.06.2021 - 12:02 Uhr