Researcher

Prof. Dr. med. Markus Glatzel FIS Profil Researchgate Profil

Prof. Dr. med. Christian Hagel FIS Profil Researchgate Profil

PD Dr. Christian Bernreuther FIS Profil

PD Dr. Jakob Matschke Researchgate Profil

PD Dr. rer. nat. Susanne Krasemann FIS Profil Researchgate Profil

Dr. rer. nat. Hermann Altmeppen FIS Profil Researchgate Profil

Dr. med. Diego Sepulveda-Falla FIS Pro FIS-Profile fil Researchgate Profil

Dr. sc. nat. Giovanna Galliciotti Researchgate Profil

Dr. rer. nat. Beata Puig Researchgate Profil

Alexander Hartmann Researchgate Profil

Christiane Muth FIS Profil

Research

A main area of research in the Department of Neuropathology involves research on mechanisms of neurodegenerative diseases. Diseases studied are prion diseases, Alzheimer’s disease and familial encephalopathy with neuroserpin inclusions (FENIB) which share the common feature of protein deposits in the brain. Our research aims at answering the following questions:

- How does the disease spread in the organism?
- Which mechanisms link pathologic protein deposits with neurodegeneration?
- How can the diagnostic process be optimised with molecularpathologic methods?

A second area of research involves neurooncology. Different projects investigate genetic alterations in tumours of the nervous system, the immunobiology of brain tumours, and especially the neuropathology of neurofibromatosis. Current projects:

  • Expression of neuronal marker proteins in brain tumors
  • The role of CD44 in cell adhesion and migration in gliomas
  • Expression of hyaluronic acid in glioma and peripheral nerve sheath tumours

Another area of research involves stem cell biology with special interest in protein degradation during differentiation of neural stem cells.

The Department of Neuropathology is part of the "Neuronal Protein Turnover" research group (spokesperson: Prof. Markus Glatzel), the Post-Graduate Study Program 1459 "Sorting and Interaction of Proteins of Subcellular Compartments" and the Leibnitz Graduate School on infectious diseases.

Experimental topics for doctoral theses are assigned to interested medical students, which will require at least nine months to complete working fulltime and at least one year when done parallel to medical school (including semester break and one free study trimester).

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