Welcome to the Laboratory for Radiobiology & Experimental Radiation Oncology

The Laboratory for Radiobiology & Experimental Radiation Oncology is part of the Department of Radiotherapy and Radiation Oncology within the Center for Oncology and the University Cancer Center Hamburg (UCCH) . We study fundamental cellular processes and obtain preclinical data in order to better understand how cells, normal tissues and tumours respond to ionising radiation. We want to utilise this information to advance the efficacy and safety of radiotherapy-based cancer treatments.

Our main focus is on the repair of radiation-induced DNA lesions, ranging from the underlying biochemical mechanisms to their clinical relevance. Specifically, we aim to identify and exploit tumour-specific deficiencies in the DNA damage response for the selective radiosensitisation of tumours using molecular-targeted agents and DNA repair-associated biomarkers.

We collaborate with numerous academic and clinical colleagues at the University Medical Center Hamburg-Eppendorf as well as with national and international partners. The Deutsche Forschungsgemeinschaft, German Cancer Aid as well as various federal government departments and charities have been supporting our work.

Head: Prof. Dr. rer. nat. Kai Rothkamm
Deputy Head: Prof. Dr. rer. nat. Kerstin Borgmann
Business Administration Manager: Prof. Dr. med. Andrea Morgner-Miehlke
Secretariat: Susanne Scheibner
Phone: +49 (0)40 7410-53593
Fax: +49 (0)40 7410-55139
e-Mail: strahlenbiologie@uke.de
Building: N27, Campus Research

Research Groups

Homologous Recombination (Head Prof. Dr. Kerstin Borgmann)
DSB Repair in Tumours (Head PD Dr. Wael Mansour)
Biological Targeting (Head PD Dr. Malte Kriegs)
Radiobiology of Head and Neck Cancer (Head PD Dr. Thorsten Rieckmann)

Teaching

PD Dr. Annette Raabe

Learned Societies and Conferences