• Klüssendorf M, Song I, Schau L, Morellini F, Dityatev A, Koliwer, Kreienkamp HJ.
    The Golgi-Associated PDZ Domain Protein Gopc/PIST Is Required for
    Synaptic Targeting of mGluR5.
    Mol Neurobiol. 2021 Aug 12. doi: 10.1007/s12035-021-02504-9
  • Yang W, Chini M, Pöpplau JA, Formozov A, Dieter A, Piechocinski P, Rais C, Morellini F, Sporns O, Hanganu-Opatz IL, Wiegert JS.
    Anesthetics fragment hippocampal network activity, alter spine dynamics, and affect memory consolidation.
    PLoS Biol. 2021 Apr 1;19(4):e3001146.
  • Kähler B, Romswinkel EV, Jakovcevski M, Moses A, Schachner M, Morellini F.
    Hyperfunction of the stress response system and novelty-induced hyperactivity correlate with enhanced cocaine-induced conditioned place preference in NCAM-deficient mice.
    Addict Biol. 2021 Mar;26(2):e12887. doi: 10.1111/adb.12887.
  • Westermann LM, Fleischhauer L, Vogel J, Jenei-Lanzl Z, Floriano Ludwig N, Schau L, Morellini F, Baranowsky A, Yorgan TA, Di Lorenzo G, Schweizer M, de Souza Pinheiro B, Guarany NR, Sperb-Ludwig F, Visioli F, Oliveira Silva T, Soul J, Hendrickx G, Wiegert JS, Schwartz IVD, Clausen-Schaumann H, Zaucke F, Schinke T, Pohl S, Danyukova T. Imbalanced cellular metabolism compromises cartilage homeostasis and joint function in a mouse model of mucolipidosis type III gamma.
    Dis Model Mech. 2020 Oct 6:dmm.046425.
  • Meier K, Merseburg A, Isbrandt D, Marguet SL, Morellini F.
    Dentate Gyrus Sharp Waves, a Local Field Potential Correlate of Learning in the Dentate Gyrus of Mice.
    J Neurosci. 2020 Sep 9;40(37):7105-7118.
  • Blechner C, Becker L, Fuchs H, Rathkolb B, Prehn C, Adler T, Calzada-Wack J, Garrett L, Gailus-Durner V, Morellini F, Conrad S, Hölter SM, Wolf E, Klopstock T, Adamski J, Busch D, de Angelis MH, Schmeisser MJ, Windhorst S.
    Physiological relevance of the neuronal isoform of inositol-1,4,5-trisphosphate 3-kinases in mice.
    Neurosci Lett. 2020 Sep 14;735:135206. doi: 10.1016/j.neulet.2020.135206.
  • Kähler B, Romswinkel EV, Jakovcevski M, Moses A, Schachner M, Morellini F.
    Hyperfunction of the stress response system and novelty-induced hyperactivity correlate with enhanced cocaine-induced conditioned place preference in NCAM-deficient mice.
    Addict Biol. 2020 Mar 2:e12887.
  • Reinicke AT*, Laban K*, Sachs M, Kraus V, Walden M, Damme M, Sachs W, Reichelt J, Schweizer M, Janiesch PC, Duncan KE, Saftig P, Rinschen MM, Morellini F*, Meyer-Schwesinger C*.
    Ubiquitin C-terminal hydrolase L1 (UCH-L1) loss causes neurodegeneration by altering protein turnover in the first postnatal weeks.
    Proc Natl Acad Sci USA. 2019 Mar 28. pii: 201812413. doi: 10.1073/pnas.1812413116.
    * Authors contributed equally to this work
  • Schob C, Morellini F, Ohana O, Bakota L, Hrynchak MV, Brandt R, Brockmann MD, Cichon N, Hartung H, Hanganu-Opatz IL, Kraus V, Scharf S, Herrmans-Borgmeyer I, Schweizer M, Kuhl D, Wöhr M, Vörckel KJ, Calzada-Wack J, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Garner CC, Kreienkamp HJ, Kindler S.
    Cognitive impairment and autistic-like behaviour in SAPAP4-deficient mice.
    Transl Psychiatry. 2019 Jan 16;9(1):7. doi: 10.1038/s41398-018-0327-z.
  • Stanelle-Bertram S, Walendy-Gnirß K, Speiseder T, Thiele S, Asante IA, Dreier C, Kouassi NM, Preuß A, Pilnitz-Stolze G, Müller U, Thanisch S, Richter M, Scharrenberg R, Kraus V, Dörk R, Schau L, Herder V4,5, Gerhauser I, Pfankuche VM, Käufer C, Waltl I, Moraes T, Sellau J, Hoenow S, Schmidt-Chanasit J, Jansen S, Schattling B, Ittrich H, Bartsch U, Renné T, Bartenschlager R, Arck P, Cadar D, Friese MA, Vapalahti O, Lotter H, Benites S, Rolling L, Gabriel M, Baumgärtner W, Morellini F, Hölter SM, Amarie O, Fuchs H, Hrabe de Angelis M, Löscher W, Calderon de Anda F, Gabriel G.
    Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood.
    Nat Microbiol. 2018 Oct;3(10):1161-1174. doi: 10.1038/s41564-018-0236-1.
  • Richter M, Murtaza N, Scharrenberg R, White SH, Johanns O, Walker S, Yuen RKC, Schwanke B, Bedürftig B, Henis M, Scharf S, Kraus V, Dörk R, Hellmann J, Lindenmaier Z, Ellegood J, Hartung H, Kwan V, Sedlacik J, Fiehler J, Schweizer M, Lerch JP, Hanganu-Opatz IL, Morellini F, Scherer SW, Singh KK, Calderon de Anda F.
    Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling. Mol Psychiatry. 2018 Feb 21. doi: 10.1038/s41380-018-0025-5.
  • Reumann R, Vierk R, Zhou L, Gries F, Kraus V, Mienert J, Romswinkel E, Morellini F, Ferrer I, Nicolini C, Fahnestock M, Rune G, Glatzel M, Galliciotti G.
    The serine protease inhibitor neuroserpin is required for normal synaptic plasticity and regulates learning and social behavior. Learn Mem. 2017 Nov 15;24(12):650-659
  • Morellini F, Malyshev A, Volgushev M, Chistiakova M, Papashvili G, Fellini L, Kleene R, Schachner M, Dityatev A.
    Impaired Fear Extinction Due to a Deficit in Ca2+ Influx Through L-Type Voltage-Gated Ca2+ Channels in Mice Deficient for Tenascin-C. Front Integr Neurosci. 2017 Aug 2;11:16.
  • Marguet SL, Le-Schulte VT, Merseburg A, Neu A, Eichler R, Jakovcevski I, Ivanov A, Hanganu-Opatz IL, Bernard C, Morellini F, Isbrandt D (2015) Treatment during a vulnerable developmental period rescues a genetic epilepsy.Nat Med. 21:1436-44
  • Hochgräfe K, Sydow A, Matenia D, Cadinu D, Könen S, Petrova O, Pickhardt M, Goll P, Morellini F, Mandelkow E, Mandelkow EM (2015).Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau. Acta Neuropathol Commun. 3:25
  • Morellini F (2013) Spatial memory tasks in rodents: what do they model? Cell Tissue Res 354:273-286.

  • Haaker J, Gaburro S, Sah A, Gartmann N, Lonsdorf TB, Meier K, Singewald N, Pape HC, Morellini F*, Kalisch R* (2013) Single dose of L-dopa makes extinction memories context-independent and prevents the return of fear. Proc Natl Acad Sci U S A 110: E2428-2436. * equally contributing authors

  • Fellini L, Morellini F (2013) Mice create what-where-when hippocampus-dependent memories of unique experiences. J Neurosci 33:1038-1043.

  • Choe CU, Nabuurs C, Stockebrand MC, Neu A, Nunes P, Morellini F, Sauter K, Schillemeit S, Hermans-Borgmeyer I, Marescau B, Heerschap A, Isbrandt D (2013) L-arginine:glycine amidinotransferase deficiency protects from metabolic syndrome. Hum Mol Genet. 22:110-123.

  • Jakovcevski M, Schachner M, Morellini F (2011) Susceptibility to the long-term anxiogenic effects of an acute stressor is mediated by the activation of the glucocorticoid receptors. Neuropharmacology 61:1297-1305.

  • Tereshchenko Y, Morellini F, Dityatev A, Schachner M, Irintchev A (2011) Neural cell adhesion molecule ablation in mice causes hippocampal dysplasia and loss of septal cholinergic neurons. J Comp Neurol 519:2475-2492.

  • Yu YM, Cristofanilli M, Valiveti A, Ma L, Yoo M, Morellini F, Schachner M (2011) The extracellular matrix glycoprotein tenascin-C promotes locomotor recovery after spinal cord injury in adult zebrafish. Neuroscience 183:238-250.

  • Fellini L, Morellini F (2011) Geometric information is required for allothetic navigation in mice. Behav Brain Res 222:380-384.

  • Morellini F, Sivukhina E, Stoenica L, Oulianova E, Bukalo O, Jakovcevski I, Dityatev A, Irintchev A, Schachner M (2010) Improved reversal learning and working memory and enhanced reactivity to novelty in mice with enhanced GABAergic innervation in the dentate gyrus. Cereb Cortex 20:2712-2727.

  • Meier I, Fellini L, Jakovcevski M, Schachner M, Morellini F (2010) Expression of the snoRNA host gene gas5 in the hippocampus is upregulated by age and psychogenic stress and correlates with reduced novelty-induced behavior in C57BL/6 mice. Hippocampus 20:1027 1036.

  • Sawallisch C, Berhörster K, Disanza A, Mantoani S, Kintscher M, Stoenica L, Dityatev A, Sieber S, Kindler S, Morellini F, Schweizer M, Boeckers TM, Korte M, Scita G, Kreienkamp HJ (2009) The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity. J Biol Chem 284:9225-9236.

  • Desarnaud F, Jakovcevski M, Morellini F, Schachner M (2008) Stress downregulates hippocampal expression of the adhesion molecules NCAM and CHL1 in mice by mechanisms independent of DNA methylation of their promoters. Cell Adh Migr 2:38-44.

  • Jakovcevski M, Schachner M, Morellini F (2008) Individual variability in the stress response of C57BL/6. Genes Brain Behav 7:235-243.

  • Tereshchenko Y, Brandewiede J, Schachner M, Irintchev A, Morellini F (2008) Novelty-induced behavioral traits correlate with numbers of brainstem noradrenergic neurons and septal cholinergic neurons in C57BL/6J mice. Behav Brain Res 191:280-284.

  • Morellini F, Lepsveridze E, Kahler B, Dityatev A, Schachner M (2007) Reduced reactivity to novelty, impaired social behavior, and enhanced basal synaptic excitatory activity in perforant path projections to the dentate gyrus in young adult mice deficient in the neural cell adhesion molecule CHL1. Mol Cell Neurosci 34:121-36.

  • Fellini L, Schachner M, Morellini F (2006) Navigation by means of geometry is impaired in aged C57BL/6J mice. Learn Mem 13:473-481.

  • Morellini F, Schachner M (2006) Enhanced novelty-induced activity, reduced anxiety, delayed resynchronization to daylight reversal and weaker muscle strength in tenascin-C deficient mice. Eur J Neurosci 23:1255-1268.

  • Orlando Guntinas-Lichius O, Angelov DN, Morellini F, Lenzen M, Skouras E, Schachner M, and Irintchev A (2005) Opposite impacts of tenascin-C and tenascin-R deficiency in mice on the functional outcome of facial nerve repair. Eur J Neurosci 22:2171-2179.

  • Irintchev A, Simova O, Eberhardt KA, Morellini F, Schachner M (2005) Impacts of lesion severity and tyrosine kinase receptor B deficiency on functional outcome of femoral nerve injury assessed by a novel single-frame motion analysis in mice. Eur J Neurosci 22:802-808.

  • Brandewiede J, Schachner M, Morellini F (2005) Ethological analysis of the senescence-accelerated P/8 mouse. Behav Brain Res 158:109-121.

  • Becker CG, Lieberoth BC, Morellini F, Feldner J, Becker T, Schachner M (2004) L1.1 is involved in spinal cord regeneration in adult zebrafish. J Neurosci 24:7837-7842.

  • Law JW, Lee AY, Sun M, Nikonenko AG, Chung SK, Dityatev A, Schachner M, Morellini F (2003) Decreased anxiety, altered place learning, and increased CA1 basal excitatory synaptic transmission in mice with conditional ablation of the neural cell adhesion molecule L1. J Neurosci 23:10419-10432.

  • Freitag S, Schachner M, Morellini F (2003) Behavioral alterations in mice deficient for the extracellular matrix glycoprotein tenascin-R. Behav. Brain Res 145:189-207.

  • Senn C, Kutsche M, Saghatelyan A, Bosl MR, Lohler J, Bartsch U, Morellini F, Schachner M (2002) Mice deficient for the HNK-1 sulfotransferase show alterations in synaptic efficacy and spatial learning and memory. Mol Cell Neurosci 20: 712-729.

  • Evers MR, Salmen B, Bukalo O, Rollenhagen A, Bosl MR, Morellini F, Bartsch U, Dityatev A, Schachner M. (2002). Impairment of L-type Ca2+ channel-dependent forms of hippocampal synaptic plasticity in mice deficient in the extracellular matrix glycoprotein tenascin-C. J Neurosci 22: 7177-7194.

  • Palanza P, Morellini F, Parmigiani S, vom Saal FS (2002) Ethological methods to study the effects of maternal exposure to estrogenic endocrine disrupters: a study with methoxychlor. Neurotoxicol Teratol 24:55-69.

  • Palanza P, Morellini F, Parmigiani S, vom Saal FS (1999) Prenatal exposure to endocrine disrupting chemicals: effects on behavioral development. Neurosci Biobehav Rev 23:1011-1027.


  • Dityatev A, Irintchev A, Morellini F, Schachner M (2007) Extracellular matrix molecules, synaptic plasticity and learning. In: Squire L (ed.) New Encyclopedia of Neuroscience, Elsevier.