Marylyn M. Addo
Prof. Dr. med. Marylyn M. Addo is a German internist, clinician scientist and specialist in infectious diseases and vaccine development. She studied medicine in Bonn (Germany), Strasbourg (France) and Lausanne (Switzerland) and received her MD degree in 1996 and her PhD in 1998.
After a Master's degree in "Applied Molecular Biology of Infectious Diseases" and a Diploma in Tropical Medicine and Hygiene (DTM & H) from the London School of Hygiene and Tropical Medicine in 1999, she did postdoctoral research in HIV immunology at the Massachusetts General Hospital (MGH) / Harvard Medical School (HMS) in Boston, USA.
She then became Assistant Professor of Medicine at Harvard Medical School. She was Director of the International Program and Group Leader at the Ragon Institute of MGH, MIT and Harvard and Associate Director of the International Program of the Harvard Center for AIDS Research (CFAR).
At the UKE, she is Full Professor (W3) of Medicine/Infectious Diseases and Head of the Division of Infectious Diseases and Tropical Medicine. Her research group and laboratories are located at both the UKE and the Department of Clinical Immunology of Infectious Diseases at the Bernhard-Nocht-Institute for Tropical Medicine.
Since 2022 she is the director of the newly funded Institute for Infection Research and Vaccine Development.
Since October 2024, Marylyn Addo has served as the spokesperson for the recently established DFG
Collaborative Research Centre 1648
, entitled "Emerging Viruses: Pathogenesis, Structure, Immunity." The Centre is dedicated to the identification of critical interactions between viruses and their hosts, as well as to the elucidation of the molecular mechanisms underlying infection processes.
Marylyn M. Addos outstanding work is published in numerous high ranking articles.
S2k-Leitlinie Gastrointestinale Infektionen der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS)
Z GASTROENTEROL. 2024;62(7):1090-1149.
Invasive Pilzinfektionen: Herausforderungen und aktuelle Entwicklungen
Addo M
DEUT MED WOCHENSCHR. 2024;149(10):541.
RSV vaccination strategies for high-risk patients 2023: a collaborative position paper by leading German medical societies and organizations
Addo M, Cornely O, Denkinger M, Ertl G, Herold S, Pletz M, Rohde G, Welte T, Windisch W, Witzenrath M
INFECTION. 2024;52(1):285-288.
Definition of the Post-COVID syndrome using a symptom-based Post-COVID score in a prospective, multi-center, cross-sectoral cohort of the German National Pandemic Cohort Network (NAPKON)
Appel K, Nürnberger C, Bahmer T, Förster C, Polidori M, Kohls M, Kraus T, Hettich-Damm N, Petersen J, Blaschke S, Bröhl I, Butzmann J, Dashti H, Deckert J, Dreher M, Fiedler K, Finke C, Geisler R, Hanses F, Hopff S, Jensen B, Konik M, Lehnert K, de Miranda S, Mitrov L, Miljukov O, Reese J, Rohde G, Scherer M, Tausche K, Tebbe J, Vehreschild J, Voit F, Wagner P, Weigl M, Lemhöfer C
INFECTION. 2024;52(5):1813-1829.
Prevalence of infectious diseases, immunity to vaccine-preventable diseases and chronic medical conditions among Ukrainian refugees in Germany - A cross sectional study from the German Network University Medicine (NUM)
Brinkmann F, Friedrichs A, Behrens G, Behrens P, Berner R, Caliebe A, Denkinger C, Giesbrecht K, Gussew A, Hoffmann A, Hojenski L, Hovardovska O, Dopfer-Jablonka A, Kaasch A, Kobbe R, Kraus M, Lindner A, Maier C, Mitrov L, Nauck M, de Miranda S, Scherer M, Schmiedel Y, Stahl D, Timmesfeld N, Toepfner N, Vehreschild J, Wohlgemuth W, Petersmann A, Vehreschild M
J INFECT PUBLIC HEAL. 2024;17(4):642-649.
SARS-CoV-2 vaccination may mitigate dysregulation of IL-1/IL-18 and gastrointestinal symptoms of the post-COVID-19 condition
Fischer C, Willscher E, Paschold L, Gottschick C, Klee B, Diexer S, Bosurgi L, Dutzmann J, Sedding D, Frese T, Girndt M, Hoell J, Gekle M, Addo M, Schulze Zur Wiesch J, Mikolajczyk R, Binder M, Schultheiß C
NPJ VACCINES. 2024;9(1):23.
Identification of a spike-specific CD8+ T cell epitope following vaccination against the Middle East respiratory syndrome coronavirus in humans
Harrer C, Mayer L, Fathi A, Lassen S, Ly M, Zinser M, Wolf T, Becker S, Sutter G, Dahlke C, Addo M
J INFECT DIS. 2024;230(2):e327-e332.
Leitlinienreport der aktualisierten S2k-Leitlinie Gastrointestinale Infektionen der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS)
Klug L, Lorenz P, Addo M, Lohse A, Manthey C, Reuken P, Stallmach A, Jansen P
Z GASTROENTEROL. 2024;62(7):e517-e530.
Delayed Induction of Noninflammatory SARS-CoV-2 Spike-Specific IgG4 Antibodies Detected 1 Year After BNT162b2 Vaccination in Children
Kobbe R, Rau C, Schulze-Sturm U, Stahl F, Fonseca-Brito L, Diemert A, Lütgehetmann M, Addo M, Arck P, Weskamm L
PEDIATR INFECT DIS J. 2024 [Epub ahead of print];43(12):1200-3.
Challenges in Diagnosing and Treating Acutely Febrile Children with Suspected Malaria at Health Care Facilities in the Lake Mwanza Region of Tanzania
Koliopoulos P, Kayange N, Jensen C, Gröndahl B, Eichmann J, Daniel T, Huth F, Eckert T, Klamm N, Follmann M, Medina-Montaño G, Hokororo A, Pretsch L, Klüber J, Schmidt C, Züchner A, Addo M, Okamo B, Mshana S, Gehring S
AM J TROP MED HYG. 2024;110(2):202-208.
Editorial zur Aktualisierung der S2k-Leitlinie Gastrointestinale Infektionen v2.0
Manthey C, Addo M, Stallmach A, Lohse A
Z GASTROENTEROL. 2024;62(7):1088-1089.
Next-generation mpox vaccines: efficacy of mRNA-1769 compared to modified vaccinia virus Ankara in non-human primates
Mayer L, Weskamm L, Addo M
SIGNAL TRANSDUCT TAR. 2024;9(1):327.
MVA-based vaccine candidates encoding the native or prefusion-stabilized SARS-CoV-2 spike reveal differential immunogenicity in humans
Mayer L, Weskamm L, Fathi A, Kono M, Heidepriem J, Krähling V, Mellinghoff S, Ly M, Friedrich M, Hardtke S, Borregaard S, Hesterkamp T, Loeffler F, Volz A, Sutter G, Becker S, Dahlke C, Addo M
NPJ VACCINES. 2024;9(1):20.
Hybrid immunity to SARS-CoV-2 in patients with chronic lymphocytic leukemia
Mellinghoff S, Robrecht S, Sprute R, Mayer L, Weskamm L, Dahlke C, Gruell H, Teipel F, Schlößer H, Siepmann K, Thelen M, Fink A, Fischer K, Klein F, Addo M, Kolovou A, Cornely O, Eichhorst B, Hallek M, Langerbeins P
EUR J HAEMATOL. 2024;112(5):788-793.
Systems biology analysis reveals distinct molecular signatures associated with immune responsiveness to the BNT162b COVID-19 vaccine
Odak I, Riemann L, Sandrock I, Cossmann A, Ramos G, Hammerschmidt S, Ritter C, Friedrichsen M, Hassan A, Dopfer-Jablonka A, Stankov M, Weskamm L, Addo M, Ravens I, Willenzon S, Schimrock A, Ristenpart J, Janssen A, Barros-Martins J, Hansen G, Falk C, Behrens G, Förster R
EBIOMEDICINE. 2024;99:.
Safety, immunogenicity, and optimal dosing of a modified vaccinia Ankara-based vaccine against MERS-CoV in healthy adults: a phase 1b, double-blind, randomised placebo-controlled clinical trial
Raadsen M, Dahlke C, Fathi A, Hardtke S, Klüver M, Krähling V, Gerresheim G, Mayer L, Mykytyn A, Weskamm L, Zoran T, van Gorp E, Sutter G, Becker S, Haagmans B, Addo M
LANCET INFECT DIS. 2024.
Lack of evidence of acute HEV infections as a sexually transmitted disease: Data from a German cohort of PrEP users
Schäfer G, Lübke R, Degen O, Mader M, Scheiter R, Wolski A, Addo M, Schulze Zur Wiesch J, Pischke S
BRAZ J INFECT DIS. 2024;28(1):103720.
High vaccination coverage and infection rate result in a robust SARS-CoV-2-specific immunity in the majority of liver cirrhosis and transplant patients: A single-center cross-sectional study
von der Schulenburg P, Herting A, Harberts A, Lütgehetmann M, Jahnke-Triankowski J, Pischke S, Piecha F, Drolz A, Jörg V, Hübener P, Wehmeyer M, Addo M, Fischer L, Lohse A, Schulze Zur Wiesch J, Sterneck M
UNITED EUR GASTROENT. 2024;12(3):339-351.
Dissecting humoral immune responses to an MVA-vectored MERS-CoV vaccine in humans using a systems serology approach
Weskamm L, Tarnow P, Harms C, Huchon M, Raadsen M, Friedrich M, Rübenacker L, Grüttner C, Garcia M, Koch T, Becker S, Sutter G, Lhomme E, Haagmans B, Fathi A, Blois S, Dahlke C, Richert L, Addo M
ISCIENCE. 2024;27(8):110470.
Think Tbc!: An Tuberkulose denken, rechtzeitig diagnostizieren und sachgerecht behandeln
Addo M
DEUT MED WOCHENSCHR. 2023;148(19):1213-1214.
Positionspapier zur RSV-Schutzimpfung bei besonders gefährdeten Patientinnen und Patienten der Deutsche Gesellschaft für Pneumologie und Beatmungsmedizin e.V.
Addo M, Cornely O, Denkinger M, Ertl G, Herold S, Pletz M, Rohde G, Welte T, Windisch W, Witzenrath M
2023.
Sex differences in the percentage of IRF5 positive B cells are associated with higher production of TNF-α in women in response to TLR9 in humans
Beisel C, Jordan-Paiz A, Köllmann S, Ahrenstorf A, Padoan B, Barkhausen T, Addo M, Altfeld M
BIOL SEX DIFFER. 2023;14(1):11.
Comparative analysis of characteristics and outcomes in hospitalized COVID-19 patients infected with different SARS-CoV-2 variants between January 2020 and April 2022 - A retrospective single-center cohort study
Brehm T, Heyer A, Woo M, Fischer M, van der Meirschen M, Wichmann D, Jarczak D, Roedl K, Schmiedel S, Addo M, Lütgehetmann M, Christner M, Huber S, Lohse A, Kluge S, Schulze Zur Wiesch J
J INFECT PUBLIC HEAL. 2023;16(11):1806-1812.
Mini-laparoscopy as a diagnostic tool for abdominal tuberculosis: a retrospective series of 29 cases
Brehm T, Ndzedzeka-Völz N, Wehmeyer M, Christner M, Clauditz T, Hübener P, Addo M, Lohse A, Schmiedel S
SURG ENDOSC. 2023;37(3):1830-1837.
Frequency of IRF5+ dendritic cells is associated with the TLR7-induced inflammatory cytokine response in SARS-CoV-2 infection
Cords L, Woost R, Kummer S, Brehm T, Kluge S, Schmiedel S, Jordan S, Lohse A, Altfeld M, Addo M, Schulze Zur Wiesch J, Beisel C
CYTOKINE. 2023;162:.
Epidemiology of co-infections in pregnant women living with human immunodeficiency virus 1 in rural Gabon: a cross-sectional study
Davi S, Okwu D, Luetgehetmann M, Abba F, Aepfelbacher M, Endamne L, Alabi A, Zoleko-Manego R, Mombo-Ngoma G, Mahmoudou S, Addo M, Ramharter M, Mischlinger J
INFECT DIS POVERTY. 2023;12(1):.
Anti-SARS-CoV-2 antibody-containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19: a randomized clinical trial
Denkinger C, Janssen M, Schäkel U, Gall J, Leo A, Stelmach P, Weber S, Krisam J, Baumann L, Stermann J, Merle U, Weigand M, Nusshag C, Bullinger L, Schrezenmeier J, Bornhäuser M, Alakel N, Witzke O, Wolf T, Vehreschild M, Schmiedel S, Addo M, Herth F, Kreuter M, Tepasse P, Hertenstein B, Hänel M, Morgner A, Kiehl M, Hopfer O, Wattad M, Schimanski C, Celik C, Pohle T, Ruhe M, Kern W, Schmitt A, Lorenz H, Souto-Carneiro M, Gaeddert M, Halama N, Meuer S, Kräusslich H, Müller B, Schnitzler P, Parthé S, Bartenschlager R, Gronkowski M, Klemmer J, Schmitt M, Dreger P, Kriegsmann K, Schlenk R, Müller-Tidow C
NAT CANCER. 2023;4(1):96-107.
Predictors of somatic symptom burden in healthcare professionals during the COVID-19 pandemic: an 8-week follow-up study
Engelmann P, Toussaint A, Addo M, Brehm T, Lohse A, Weigel A, Thompson M, Löwe B
J MENT HEALTH. 2023;32(6):1111-1121.
High burden of RSV and influenza in patients presenting with suspected pneumonia in the emergency room of a German tertiary hospital in fall of 2022
Ettemeyer M, Florey M, Tanida K, Jochum J, Schulze-Sturm U, Lütgehetmann M, Baehr M, Addo M, Schmiedel S, Rohde H, Koch T
INFECTION. 2023;51(5):1569-1575.
Impact of antibiotic intake on the incidence of extended-spectrum β-lactamase-producing Enterobacterales in sub-Saharan Africa
Heinemann M, Kleinjohann L, Rolling T, Winter D, Hackbarth N, Ramharter M, Addo M, Eibach D, Phillips R, Owusu-Ofori A, Vinnemeier C
CLIN MICROBIOL INFEC. 2023;29(3):340-345.
Tecovirimat for the treatment of severe Mpox in Germany
Hermanussen L, Brehm T, Wolf T, Boesecke C, Schlabe S, Borgans F, Monin M, Jensen B, Windhaber S, Scholten S, Jordan S, Lütgehetmann M, Wiesch J, Addo M, Mikolajewska A, Niebank M, Schmiedel S
INFECTION. 2023;51(5):1563-1568.
Tecovirimat therapy for severe monkeypox infection: Longitudinal assessment of viral titers and clinical response pattern-A first case-series experience
Hermanussen L, Grewe I, Tang H, Nörz D, Bal L, Pfefferle S, Unger S, Hoffmann C, Berzow D, Kohsar M, Aepfelbacher M, Lohse A, Addo M, Lütgehetmann M, Schulze zur Wiesch J, Schmiedel S
J MED VIROL. 2023;95(1):e28181.
Clinical Outcomes of SARS-CoV-2 Breakthrough Infections in Liver Transplant Recipients during the Omicron Wave
Herting A, Jahnke-Triankowski J, Harberts A, Schaub G, Lütgehetmann M, Ruether D, Fischer L, Addo M, Lohse A, Schulze Zur Wiesch J, Sterneck M
VIRUSES-BASEL. 2023;15(2):.
Discovery and systematic assessment of early biomarkers that predict progression to severe COVID-19 disease
Hufnagel K, Fathi A, Stroh N, Klein M, Skwirblies F, Girgis R, Dahlke C, Hoheisel J, Lowy C, Schmidt R, Griesbeck A, Merle U, Addo M, Schröder C
COMMUN MED-LONDON. 2023;3(1):51.
Antibody responses to recombinant vesicular stomatitis virus-Zaire Ebolavirus vaccination for Ebola virus disease across doses and continents: 5-year durability
Huttner A, Agnandji S, Engler O, Hooper J, Kwilas S, Ricks K, Clements T, Jonsdottir H, Nakka S, Rothenberger S, Kremsner P, Züst R, Medaglini D, Ottenhoff T, Harandi A, Siegrist C
CLIN MICROBIOL INFEC. 2023;29(12):1587-1594.
History of cerebrovascular disease but not dementia increases the risk for secondary vascular events during SARS-CoV-2 infection with presumed Omicron variant: a retrospective observational study
Mayer C, Woo M, Brehm T, Heyer A, Fischer M, Fischbach F, Bal L, Addo M, Kluge S, Thomalla G, Schweingruber N, Wiesch J
EUR J NEUROL. 2023;30(8):2297-2304.
β-Propiolactone (BPL)-inactivation of SARS-Co-V-2: In vitro validation with focus on saliva from COVID-19 patients for scent dog training
Pilchová V, Prajeeth C, Jendrny P, Twele F, Meller S, Pink I, Fathi A, Addo M, Volk H, Osterhaus A, von Köckritz-Blickwede M, Schulz C
J VIROL METHODS. 2023;317:.
Monkeypox Virus Cross-Neutralizing Antibodies in Clinical Trial Participants Vaccinated With Modified Vaccinia Virus Ankara Encoding Middle East Respiratory Syndrome–Coronavirus Spike Protein
Raadsen M, Dahlke C, Fathi A, Lamers M, van den Doel P, Zaeck L, van Royen M, de Bruin E, Sikkema R, Koopmans M, van Gorp E, Sutter G, de Vries R, Addo M, Haagmans B
J INFECT DIS. 2023;228(5):586-590.
Symptoms of illness during travel and risk factors for non-adherence to malaria prophylaxis-a cross-sectional study in travellers from Germany
Reinsberg F, Moehlmann M, Krumkamp R, Landsmann L, Heitkamp C, Jochum J, Addo M, Ramharter M, Radt C, Rothe C, Vinnemeier C, Kreuels B
J TRAVEL MED. 2023;30(3):taad055.
Persistent symptoms and risk factors predicting prolonged time to symptom-free after SARS‑CoV‑2 infection: an analysis of the baseline examination of the German COVIDOM/NAPKON-POP cohort
Shi Y, Strobl R, Apfelbacher C, Bahmer T, Geisler R, Heuschmann P, Horn A, Hoven H, Keil T, Krawczak M, Krist L, Lemhöfer C, Lieb W, Lorenz-Depiereux B, Mikolajczyk R, Montellano F, Reese J, Schreiber S, Skoetz N, Störk S, Vehreschild J, Witzenrath M, Grill E
INFECTION. 2023;51(6):1679-1694.
Evidence for broad cross-reactivity of the SARS-CoV-2 NSP12-directed CD4+ T-cell response with pre-primed responses directed against common cold coronaviruses
Westphal T, Mader M, Karsten H, Cords L, Knapp M, Schulte S, Hermanussen L, Peine S, Ditt V, Grifoni A, Addo M, Huber S, Sette A, Lütgehetmann M, Pischke S, Kwok W, Sidney J, Schulze Zur Wiesch J
FRONT IMMUNOL. 2023;14:.
Higher Risk of HEV Transmission and Exposure among Blood Donors in Europe and Asia in Comparison to North America: A Meta-Analysis
Wolski A, Pischke S, Ozga A, Addo M, Horvatits T
PATHOGENS. 2023;12(3):425.
Sotrovimab in Hospitalized Patients with SARS-CoV-2 Omicron Variant Infection: a Propensity Score-Matched Retrospective Cohort Study
Woo M, Brehm T, Fischer M, Heyer A, Wichmann D, Jordan S, Nörz D, Lütgehetmann M, Addo M, Lohse A, Schmiedel S, Kluge S, Schulze Zur Wiesch J
MICROBIOL SPECTR. 2023;11(1):.
Absence of self-reported neuropsychiatric and somatic symptoms after Omicron variant SARS-CoV-2 breakthrough infections
Woo M, Mayer C, Brehm T, Andersen G, Weigel A, Löwe B, Lohse A, Addo M, Gerloff C, Knobloch J, Schulze Zur Wiesch J, Friese M
BRAIN COMMUN. 2023;5(2):fcad092.
Vagus nerve inflammation contributes to dysautonomia in COVID-19
Woo M, Shafiq M, Fitzek A, Dottermusch M, Altmeppen H, Mohammadi B, Mayer C, Bal L, Raich L, Matschke J, Krasemann S, Pfefferle S, Brehm T, Lütgehetmann M, Schädler J, Addo M, Schulze Zur Wiesch J, Ondruschka B, Friese M, Glatzel M
ACTA NEUROPATHOL. 2023;146(3):387-394.
Notfallimpfstoffe: Wie sieht die Zukunft aus?
Addo M
2022. Infektionen und Gesellschaft. Lohse A, Mettenleiter T (eds.). 1. ed. Berlin, Heidelberg: Springer Spektrum, Berlin, Heidelberg, 68-71.
Reisemedizin nimmt wieder an Fahrt auf!
Addo M
DEUT MED WOCHENSCHR. 2022;147(12):729-730.
T cells expressing multiple co-inhibitory molecules in acute malaria are not exhausted but exert a suppressive function in mice
Brandi J, Lehmann C, Kaminski L, Schulze Zur Wiesch J, Addo M, Ramharter M, Mackroth M, Jacobs T, Riehn M
EUR J IMMUNOL. 2022;52(2):312-327.
Attitudes, practices, and obstacles towards influenza vaccination for international travelers among travel health advisors in Germany: A questionnaire-based survey
Brehm T, Jordan S, Addo M, Ramharter M, Kreuels B
TRAVEL MED INFECT DI. 2022;45:.
Clinical efficacy and in vitro neutralization capacity of monoclonal antibodies for severe acute respiratory syndrome coronavirus 2 delta and omicron variants
Brehm T, Pfefferle S, von Possel R, Karolyi M, Zoufaly A, Wichmann D, Kobbe R, Emmerich P, Nörz D, Aepfelbacher M, Schulze Zur Wiesch J, Addo M, Schmiedel S, Lütgehetmann M
J MED VIROL. 2022;94(10):5038-5043.
Three Separate Spike Antigen Exposures by COVID-19 Vaccination or SARS-CoV-2 Infection Elicit Strong Humoral Immune Responses in Healthcare Workers
Brehm T, Ullrich F, Thompson M, Küchen J, Schwinge D, Spier A, Huber S, Knobloch J, Aepfelbacher M, Addo M, Lohse A, Lütgehetmann M, Schulze Zur Wiesch J
VACCINES-BASEL. 2022;10(7):.
High and Sustained Ex Vivo Frequency but Altered Phenotype of SARS-CoV-2-Specific CD4+ T-Cells in an Anti-CD20-Treated Patient with Prolonged COVID-19
Cords L, Knapp M, Woost R, Schulte S, Kummer S, Ackermann C, Beisel C, Peine S, Johansson A, Kwok W, Günther T, Fischer N, Wittner M, Addo M, Huber S, Schulze Zur Wiesch J
VIRUSES-BASEL. 2022;14(6):.
SARS-CoV-2 vaccination response in patients with autoimmune hepatitis and autoimmune cholestatic liver disease
Duengelhoef P, Hartl J, Rüther D, Steinmann S, Brehm T, Weltzsch J, Glaser F, Schaub G, Sterneck M, Sebode M, Weiler-Normann C, Addo M, Lütgehetmann M, Haag F, Schramm C, Schulze Zur Wiesch J, Lohse A
UNITED EUR GASTROENT. 2022;10(3):319-329.
Risk factors for worsening of somatic symptom burden in a prospective cohort during the COVID-19 pandemic
Engelmann P, Löwe B, Brehm T, Weigel A, Ullrich F, Addo M, Schulze zur Wiesch J, Lohse A, Toussaint A
FRONT PSYCHOL. 2022;13:1022203.
Increased neutralization and IgG epitope identification after MVA-MERS-S booster vaccination against Middle East respiratory syndrome
Fathi A, Dahlke C, Krähling V, Kupke A, Okba N, Raadsen M, Heidepriem J, Müller M, Paris G, Lassen-Haartje S, Klüver M, Volz A, Koch T, Ly M, Friedrich M, Fux R, Tscherne A, Kalodimou G, Schmiedel S, Corman V, Hesterkamp T, Drosten C, Loeffler F, Haagmans B, Sutter G, Becker S, Addo M
NAT COMMUN. 2022;13(1):4182.
Natural killer cell-mediated ADCC in SARS-CoV-2-infected individuals and vaccine recipients
Hagemann K, Riecken K, Jung J, Hildebrandt H, Menzel S, Bunders M, Fehse B, Koch-Nolte F, Heinrich F, Peine S, Schulze Zur Wiesch J, Brehm T, Addo M, Lütgehetmann M, Altfeld M
EUR J IMMUNOL. 2022;52(8):1297-1307.
Humoral and Cellular Immune Response After Third and Fourth SARS-CoV-2 mRNA Vaccination in Liver Transplant Recipients
Harberts A, Schaub G, Ruether D, Duengelhoef P, Brehm T, Karsten H, Fathi A, Jahnke-Triankowski J, Fischer L, Addo M, Haag F, Lütgehetmann M, Lohse A, Schulze zur Wiesch J, Sterneck M
CLIN GASTROENTEROL H. 2022;20(11):2558-2566.e5.
Respiratory muscle dysfunction in long-COVID patients
Hennigs J, Huwe M, Hennigs A, Oqueka T, Simon M, Harbaum L, Körbelin J, Schmiedel S, Schulze Zur Wiesch J, Addo M, Kluge S, Klose H
INFECTION. 2022;50(5):1391-1397.
Remdesivir-induced emergence of SARS-CoV2 variants in patients with prolonged infection
Heyer A, Günther T, Robitaille A, Lütgehetmann M, Addo M, Jarczak D, Kluge S, Aepfelbacher M, Schulze Zur Wiesch J, Fischer N, Grundhoff A
CELL REP MED. 2022;3(9):.
Die COVID-19-Pandemie – ein epochales Ereignis
Janssens U, Addo M, von Bergwelt-Baildon M
DEUT MED WOCHENSCHR. 2022;147(20):1297-1298.
Erratum: Die COVID-19-Pandemie – ein epochales Ereignis
Janssens U, Addo M, von Bergwelt-Baildon M
DEUT MED WOCHENSCHR. 2022;147(20):e114.
High-resolution analysis of individual spike peptide-specific CD4+ T-cell responses in vaccine recipients and COVID-19 patients
Karsten H, Cords L, Westphal T, Knapp M, Brehm T, Hermanussen L, Omansen T, Schmiedel S, Woost R, Ditt V, Peine S, Lütgehetmann M, Huber S, Ackermann C, Wittner M, Addo M, Sette A, Sidney J, Schulze Zur Wiesch J
CLIN TRANSL IMMUNOL. 2022;11(8):.
Eine Erhebung zum Impfstatus von COVID-19-Patienten auf Normal- und Intensivstationen in Hamburg
Kluge S, Jarczak D, Eberhardt R, Herrlinger K, Janneck M, Borlich O, Weber C, Schley J, Emami P, Bergmann M, Addo M, Kerner T
DEUT MED WOCHENSCHR. 2022;147(8):492-494.
Statistical biases due to anonymization evaluated in an open clinical dataset from COVID-19 patients
Koll C, Hopff S, Meurers T, Lee C, Kohls M, Stellbrink C, Thibeault C, Reinke L, Steinbrecher S, Schreiber S, Mitrov L, Frank S, Miljukov O, Erber J, Hellmuth J, Reese J, Steinbeis F, Bahmer T, Hagen M, Meybohm P, Hansch S, Vadász I, Krist L, Jiru-Hillmann S, Prasser F, Vehreschild J
SCI DATA. 2022;9(1):.
SARS-CoV-2-specific cellular response following third COVID-19 vaccination in patients with chronic lymphocytic leukemia
Mellinghoff S, Mayer L, Robrecht S, Weskamm L, Dahlke C, Gruell H, Schlotz M, Vanshylla K, Schloser H, Thelen M, Fink A, Fischer K, Klein F, Addo M, Eichhorst B, Hallek M, Langerbeins P
HAEMATOLOGICA. 2022;107(10):2480-2484.
SARS-CoV-2 specific cellular response following COVID-19 vaccination in patients with chronic lymphocytic leukemia
Mellinghoff S, Robrecht S, Mayer L, Weskamm L, Dahlke C, Gruell H, Vanshylla K, Schlösser H, Thelen M, Fink A, Fischer K, Klein F, Addo M, Eichhorst B, Hallek M, Langerbeins P
LEUKEMIA. 2022;36(2):562-565.
Debunking Misinformation and Communicating Critical Events in Vaccine Trials: Experimental Evidence on Vaccination Intentions in SARS-CoV-2 Pandemic
Memenga P, Eitze S, Shamsrizi P, Addo M, Betsch C
European Journal of Health Communication. 2022;3(2):64-96.
Stabilized recombinant SARS-CoV-2 spike antigen enhances vaccine immunogenicity and protective capacity
Meyer Zu Natrup C, Tscherne A, Dahlke C, Ciurkiewicz M, Shin D, Fathi A, Rohde C, Kalodimou G, Halwe S, Limpinsel L, Schwarz J, Klug M, Esen M, Schneiderhan-Marra N, Dulovic A, Kupke A, Brosinski K, Clever S, Schünemann L, Beythien G, Armando F, Mayer L, Weskamm L, Jany S, Freudenstein A, Tuchel T, Baumgärtner W, Kremsner P, Fendel R, Addo M, Becker S, Sutter G, Volz A
J CLIN INVEST. 2022;132(24):.
Clinical characteristics and comparison of longitudinal qPCR results from different specimen types in a cohort of ambulatory and hospitalized patients infected with monkeypox virus
Nörz D, Brehm T, Tang H, Grewe I, Hermanussen L, Matthews H, Pestel J, Degen O, Günther T, Grundhoff A, Fischer N, Addo M, Jordan S, Hertling S, Unger S, Schäfer G, Schewe K, Hoffmann C, Aepfelbacher M, Pfefferle S, Schulze Zur Wiesch J, Schmiedel S, Lütgehetmann M
J CLIN VIROL. 2022;155:.
Evidence of surface contamination in hospital rooms occupied by patients infected with monkeypox, Germany, June 2022
Nörz D, Pfefferle S, Brehm T, Franke G, Grewe I, Knobling B, Aepfelbacher M, Huber S, Klupp E, Jordan S, Addo M, Schulze Zur Wiesch J, Schmiedel S, Lütgehetmann M, Knobloch J
EUROSURVEILLANCE. 2022;27(26):.
Rapid Adaptation of Established High-Throughput Molecular Testing Infrastructure for Monkeypox Virus Detection
Nörz D, Tang H, Emmerich P, Giersch K, Fischer N, Schmiedel S, Addo M, Aepfelbacher M, Pfefferle S, Lütgehetmann M
EMERG INFECT DIS. 2022;28(9):1765-1769.
The effects of SARS-CoV-2 virus type and of vaccination status on causes of death over the course of the COVID-19 pandemic
Paparoupa M, Schröder A, Braunsteiner J, Addo M, Lütgehetmann M, Roedl K, Kluge S, Ondruschka B, Wichmann D
DTSCH ARZTEBL INT. 2022;119(35-36):607-608.
SARS-CoV2-specific humoral and T-cell immune response after second vaccination in liver cirrhosis and transplant patients
Ruether D, Schaub G, Duengelhoef P, Haag F, Brehm T, Fathi A, Wehmeyer M, Jahnke-Triankowski J, Mayer L, Hoffmann A, Fischer L, Addo M, Lütgehetmann M, Lohse A, Schulze Zur Wiesch J, Sterneck M
CLIN GASTROENTEROL H. 2022;20(1):162-172.e9.
The German National Pandemic Cohort Network (NAPKON): rationale, study design and baseline characteristics
Schons M, Pilgram L, Reese J, Stecher M, Anton G, Appel K, Bahmer T, Bartschke A, Bellinghausen C, Bernemann I, Brechtel M, Brinkmann F, Brünn C, Dhillon C, Fiessler C, Geisler R, Hamelmann E, Hansch S, Hanses F, Hanß S, Herold S, Heyder R, Hofmann A, Hopff S, Horn A, Jakob C, Jiru-Hillmann S, Keil T, Khodamoradi Y, Kohls M, Kraus M, Krefting D, Kunze S, Kurth F, Lieb W, Lippert L, Lorbeer R, Lorenz-Depiereux B, Maetzler C, Miljukov O, Nauck M, Pape D, Püntmann V, Reinke L, Römmele C, Rudolph S, Sass J, Schäfer C, Schaller J, Schattschneider M, Scheer C, Scherer M, Schmidt S, Schmidt J, Seibel K, Stahl D, Steinbeis F, Störk S, Tauchert M, Tebbe J, Thibeault C, Toepfner N, Ungethüm K, Vadasz I, Valentin H, Wiedmann S, Zoller T, Nagel E, Krawczak M, von Kalle C, Illig T, Schreiber S, Witzenrath M, Heuschmann P, Vehreschild J
EUR J EPIDEMIOL. 2022;37(8):849-870.
Erratum zu: Milde COVID-19-Verläufe bei Mitarbeitenden einer Universitätsklinik : Die „erste Welle“ am Universitätsklinikum Hamburg-Eppendorf
von Felden J, Brehm T, Schulze Zur Wiesch J, Addo M, Lohse A, Knobloch J, Koch T
BUNDESGESUNDHEITSBLA. 2022;65(3):398.
Molecular consequences of SARS-CoV-2 liver tropism
Wanner N, Andrieux G, Badia-I-Mompel P, Edler C, Pfefferle S, Lindenmeyer M, Schmidt-Lauber C, Czogalla J, Wong M, Okabayashi Y, Braun F, Lütgehetmann M, Meister E, Lu S, Noriega M, Günther T, Grundhoff A, Fischer N, Bräuninger H, Lindner D, Westermann D, Haas F, Roedl K, Kluge S, Addo M, Huber S, Lohse A, Reiser J, Ondruschka B, Sperhake J, Saez-Rodriguez J, Boerries M, Hayek S, Aepfelbacher M, Scaturro P, Puelles V, Huber T
NAT METAB. 2022;4(3):310-319.
Flow cytometric protocol to characterize human memory B cells directed against SARS-CoV-2 spike protein antigens
Weskamm L, Dahlke C, Addo M
STAR PROTOC. 2022;3(4):.
Persistence of MERS-CoV-spike-specific B cells and antibodies after late third immunization with the MVA-MERS-S vaccine
Weskamm L, Fathi A, Raadsen M, Mykytyn A, Koch T, Spohn M, Friedrich M, , Haagmans B, Becker S, Sutter G, Dahlke C, Addo M
CELL REP MED. 2022;3(7):.
Digital PCR to quantify ChAdOx1 nCoV-19 copies in blood and tissues
Badbaran A, Mailer R, Dahlke C, Woens J, Fathi A, Mellinghoff S, Renné T, Addo M, Riecken K, Fehse B
MOL THER-METH CLIN D. 2021;23:418-423.
Patient Characteristics and Clinical Course of COVID-19 Patients Treated at a German Tertiary Center during the First and Second Waves in the Year 2020
Brehm T, Heyer A, Roedl K, Jarczak D, Nierhaus A, Nentwich M, van der Meirschen M, Schultze A, Christner M, Fiedler W, Kröger N, Huber T, Klose H, Sterneck M, Jordan S, Kreuels B, Schmiedel S, Addo M, Huber S, Lohse A, Kluge S, Schulze Zur Wiesch J
J CLIN MED. 2021;10(11):.
SARS-CoV-2 Reinfection in a Healthcare Worker Despite the Presence of Detectable Neutralizing Antibodies
Brehm T, Pfefferle S, von Possel R, Kobbe R, Nörz D, Schmiedel S, Grundhoff A, Olearo F, Emmerich P, Robitaille A, Günther T, Braun P, Andersen G, Knobloch J, Addo M, Lohse A, Aepfelbacher M, Fischer N, Schulze Zur Wiesch J, Lütgehetmann M
VIRUSES-BASEL. 2021;13(4):.
Seroprevalence of SARS-CoV-2 antibodies among hospital workers in a German tertiary care center: A sequential follow-up study
Brehm T, Schwinge D, Lampalzer S, Schlicker V, Küchen J, Thompson M, Ullrich F, Huber S, Schmiedel S, Addo M, Lütgehetmann M, Knobloch J, Schulze Zur Wiesch J, Lohse A
INT J HYG ENVIR HEAL. 2021;232:.
Low SARS-CoV-2 infection rates and high vaccine-induced immunity among German healthcare workers at the end of the third wave of the COVID-19 pandemic
Brehm T, Thompson M, Ullrich F, Schwinge D, Addo M, Spier A, Knobloch J, Aepfelbacher M, Lohse A, Lütgehetmann M, Schulze Zur Wiesch J
INT J HYG ENVIR HEAL. 2021;238:.
Comparison of clinical characteristics and disease outcome of COVID-19 and seasonal influenza
Brehm T, van der Meirschen M, Hennigs A, Roedl K, Jarczak D, Wichmann D, Frings D, Nierhaus A, Oqueka T, Fiedler W, Christopeit M, Kraef C, Schultze A, Lütgehetmann M, Addo M, Schmiedel S, Kluge S, Schulze Zur Wiesch J
SCI REP-UK. 2021;11(1):.
Hepatitis E seroprevalence and viremia rate in immunocompromised patients: a systematic review and meta-analysis
Buescher G, Ozga A, Lorenz E, Pischke S, May J, Addo M, Horvatits T
LIVER INT. 2021;41(3):449-455.
Weniger ist mehr … in der Infektiologie
Fathi A, Hennigs A, Addo M
INTERNIST. 2021;62(4):373-378.
A call to caution when hydroxychloroquine is given to elderly patients with COVID-19
Gabor J, Kreidenweiss A, Weber S, Salama M, Sulyok M, Sulyok Z, Koehne E, Esen M, Kreuels B, Shamsrizi P, Biecker E, Mordmüller B, Berg C, Fusco S, Köhler C, Kubicka S, Leitlein J, Addo M, Ramharter M, Schwab M, Bissinger A, Velavan T, Krishna S, Kremsner P
INT J INFECT DIS. 2021;106:265-268.
Clinical presentation and disease course of 37 consecutive cases of progressive multifocal leukoencephalopathy (PML) at a German tertiary-care hospital: a retrospective observational study
Graf L, Rosenkranz S, Hölzemer A, Hagel C, Goebell E, Jordan S, Friese M, Addo M, Schulze zur Wiesch J, Beisel C
FRONT NEUROL. 2021;12:632535.
Validation of a Prospective Urinalysis-Based Prediction Model for ICU Resources and Outcome of COVID-19 Disease: A Multicenter Cohort Study
Gross O, Moerer O, Rauen T, Böckhaus J, Hoxha E, Jörres A, Kamm M, Elfanish A, Windisch W, Dreher M, Floege J, Kluge S, Schmidt-Lauber C, Turner J, Huber S, Addo M, Scheithauer S, Friede T, Braun G, Huber T, Blaschke S
J CLIN MED. 2021;10(14):.
A simple, sensitive, and low-cost FACS assay for detecting antibodies against the native SARS-CoV-2 spike protein
Hambach J, Stähler T, Eden T, Wendt D, Tode N, Haag F, Tolosa E, Altfeld M, Fathi A, Dahlke C, Addo M, Menzel S, Koch-Nolte F
IMMUN INFLAMM DIS. 2021;9(3):905-917.
Longitudinal development of antibody responses in covid-19 patients of different severity with elisa, peptide, and glycan arrays: An immunological case series
Heidepriem J, Dahlke C, Kobbe R, Santer R, Koch T, Fathi A, Seco B, Ly M, Schmiedel S, Schwinge D, Serna S, Sellrie K, Reichardt N, Seeberger P, Addo M, Loeffler F
PATHOGENS. 2021;10(4):.
Hepatitis E virus persists in the ejaculate of chronically infected men
Horvatits T, Wißmann J, Johne R, Groschup M, Gadicherla A, Wiesch J, Eiden M, Todt D, Reimer R, Dähnert L, Schöbel A, Horvatits K, Lübke R, Wolschke C, Ayuk F, Rybczynski M, Lohse A, Addo M, Herker E, Lütgehetmann M, Steinmann E, Pischke S
J HEPATOL. 2021;75(1):55-63.
Extensive Antibiotic and Antimalarial Prescription Rate among Children with Acute Febrile Diseases in the Lake Victoria Region, Tanzania
Huth P, Addo M, Daniel T, Groendahl B, Hokororo A, Koliopoulos P, Mshana S, Pretsch L, Schmidt C, Zuechner A, Gehring S, Kayange N
J TROP PEDIATRICS. 2021;67(1):fmaa135.
Scent dog identification of SARS-CoV-2 infections in different body fluids
Jendrny P, Twele F, Meller S, Schulz C, von Köckritz-Blickwede M, Osterhaus A, Ebbers H, Ebbers J, Pilchová V, Pink I, Welte T, Manns M, Fathi A, Addo M, Ernst C, Schäfer W, Engels M, Petrov A, Marquart K, Schotte U, Schalke E, Volk H
BMC INFECT DIS. 2021;21(1):.
Malaria in the Time of COVID-19: Do Not Miss the Real Cause of Illness
Jochum J, Kreuels B, Tannich E, Huber S, Schulze Zur Wiesch J, Schmiedel S, Ramharter M, Addo M
TROP MED INFECT DIS. 2021;6(2):.
The COVID-19 Vaccine Landscape
Koch T, Fathi A, Addo M
ADV EXP MED BIOL. 2021;1318:549-573.
Correlates of Vaccine-Induced Protection against SARS-CoV-2
Koch T, Mellinghoff S, Shamsrizi P, Addo M, Dahlke C
VACCINES-BASEL. 2021;9(3):.
Multiplex-RT-PCR-ELISA panel for detecting mosquito-borne pathogens: Plasmodium sp. preserved and eluted from dried blood spots on sample cards
Koliopoulos P, Kayange N, Daniel T, Huth F, Gröndahl B, Medina-Montaño G, Pretsch L, Klüber J, Schmidt C, Züchner A, Ulbert S, Mshana S, Addo M, Gehring S
MALARIA J. 2021;20(1):.
Infektionen und Gesellschaft
Lohse A, Addo M
2021. Infektionen und Gesellschaft. Lohse A (eds.). 1. ed. Hamburg: Springer, 3-4; 135-147.
Case Report - Clinical Management of a Patient With Metastatic Non-Small Cell Lung Cancer Newly Receiving Immune Checkpoint Inhibition During Symptomatic COVID-19
Mellinghoff S, Vanshylla K, Dahlke C, Addo M, Cornely O, Klein F, Persigehl T, Rybniker J, Gruell H, Bröckelmann P
FRONT IMMUNOL. 2021;12:.
TIPS and splenorenal shunt for complications of portal hypertension in chronic hepatosplenic schistosomiasis-A case series and review of the literature
Nordmann T, Schlabe S, Feldt T, Gobbi F, Krieg A, Bode J, Fuchs A, Kraef C, Praktiknjo M, Trebicka J, Ramharter M, Addo M, Strassburg C, Lohse A, Luedde T, Schmiedel S, Orth H
PLOS NEGLECT TROP D. 2021;15(12):.
Risk factors for and management of metronidazole-refractory giardiasis in international travellers: A retrospective analysis
Peters T, Kreuels B, Addo M, Tannich E, Rothe C
TRAVEL MED INFECT DI. 2021;43:.
Lack of Evidence for an Association between Previous HEV Genotype-3 Exposure and Glomerulonephritis in General
Pischke S, Tamanaei S, Mader M, Wiesch J, Petersen-Benz C, Haddad M, Addo M, Schmidt T, Huber T, Krebs C, Steinmetz O, Turner J, Hoxha E, Horvatits T
PATHOGENS. 2021;11(1):.
Characterization of Individuals Interested in Participating in a Phase I SARS-CoV-2 Vaccine Trial
Shamsrizi P, Kramer F, Addo M, Fathi A
VACCINES-BASEL. 2021;9(10):1208.
Discrimination of SARS-CoV-2 Infections From Other Viral Respiratory Infections by Scent Detection Dogs
Ten Hagen N, Twele F, Meller S, Jendrny P, Schulz C, von Köckritz-Blickwede M, Osterhaus A, Ebbers H, Pink I, Welte T, Manns M, Illig T, Fathi A, Addo M, Nitsche A, Puyskens A, Michel J, Krause E, Ehmann R, von Brunn A, Ernst C, Zwirglmaier K, Wölfel R, Nau A, Philipp E, Engels M, Schalke E, Volk H
FRONT MED-LAUSANNE. 2021;8:.
Less than you'd think-a prospective study on MRSA-colonization in healthy travellers
Tran D, Winter D, Christner M, Ramharter M, Addo M, Rolling T, Vinnemeier C, Koch T
J TRAVEL MED. 2021;28(3):.
Longitudinal monitoring of laboratory markers characterizes hospitalized and ambulatory COVID-19 patients
Velavan T, Kuk S, Linh L, Lamsfus Calle C, Lalremruata A, Pallerla S, Kreidenweiss A, Held J, Esen M, Gabor J, Neurohr E, Shamsrizi P, Fathi A, Biecker E, Berg C, Ramharter M, Addo M, Kreuels B, Kremsner P
SCI REP-UK. 2021;11(1):.
Update 2021: COVID-19 aus Sicht der internistischen Schwerpunkte
von Bergwelt-Baildon M, Addo M
DEUT MED WOCHENSCHR. 2021;146(13-14):.
Milde COVID-19-Verläufe bei Mitarbeitenden einer Universitätsklinik: Die „erste Welle“ am Universitätsklinikum Hamburg-Eppendorf
von Felden J, Brehm T, Schulze-Zur-Wiesch J, Addo M, Lohse A, Knobloch J, Koch T
BUNDESGESUNDHEITSBLA. 2021;64(9):1165-1168.
B cell analysis in SARS‐CoV‐2 versus malaria: Increased frequencies of plasmablasts and atypical memory B cells in COVID‐19
Wildner N, Ahmadi P, Schulte S, Brauneck F, Kohsar M, Lütgehetmann M, Beisel C, Addo M, Haag F, Schulze zur Wiesch J
J LEUKOCYTE BIOL. 2021;109(1):77-90.
Multi-dimensional and longitudinal systems profiling reveals predictive pattern of severe COVID-19
Woo M, Haag F, Nierhaus A, Jarczak D, Roedl K, Mayer C, Brehm T, van der Meirschen M, Hennigs A, Christopeit M, Fiedler W, Karagiannis P, Burdelski C, Schultze A, Huber S, Addo M, Schmiedel S, Friese M, Kluge S, Schulze Zur Wiesch J
ISCIENCE. 2021;24(7):102752.
Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients
Zhao Y, Kilian C, Turner J, Bosurgi L, Roedl K, Bartsch P, Gnirck A, Cortesi F, Schultheiß C, Hellmig M, Enk L, Hausmann F, Borchers A, Wong M, Paust H, Siracusa F, Scheibel N, Herrmann M, Rosati E, Bacher P, Kylies D, Jarczak D, Lütgehetmann M, Pfefferle S, Steurer S, Zur Wiesch J, Puelles V, Sperhake J, Addo M, Lohse A, Binder M, Huber S, Huber T, Kluge S, Bonn S, Panzer U, Gagliani N, Krebs C
SCI IMMUNOL. 2021;6(56):.
Antibiotikatherapie richtig gemacht
Addo M, Thimme R
DEUT MED WOCHENSCHR. 2020;145(23):1657.
Seroconversion of HBsAG coincides with hepatitis A super-infection: A case report
Beisel C, Addo M, Zur Wiesch J
WORLD J CLIN CASES. 2020;8(9):1651-1655.
Risk factors for different intestinal pathogens among patients with traveler's diarrhea: A retrospective analysis at a German travel clinic (2009-2017)
Brehm T, Lütgehetmann M, Tannich E, Addo M, Lohse A, Rolling T, Vinnemeier C
TRAVEL MED INFECT DI. 2020;37:101706.
High effectiveness of multimodal infection control interventions in preventing SARS−CoV−2 infections in healthcare professionals: a prospective longitudinal seroconversion study
Brehm T, Schwinge D, Lampalzer S, Schlicker V, Küchen J, Thompson M, Ullrich F, Huber S, Schmiedel S, Addo M, Lütgehetmann M, Knobloch J, Schulze zur Wiesch J, Lohse A
medRxiv BMJ. 2020.
Sex Differences in Immunity: Implications for the Development of Novel Vaccines Against Emerging Pathogens
Dahlke C, Fathi A, Addo M
FRONT IMMUNOL. 2020;11(11):601170.
Distinct early IgA profile may determine severity of COVID-19 symptoms: an immunological case series
Dahlke C, Heidepriem J, Kobbe R, Santer R, Koch T, Fathi A, Ly M, Schmiedel S, Seeberger P, , Addo M, Loeffler F
medRxiv. 2020.
Integrin alpha E (CD103) limits virus-induced IFN-I production in conventional dendritic cells
Duhan V, Khairnar V, Kitanovski S, Hamdan T, Klein A, Lang J, Ali M, Adomati T, Bhat H, Friedrich S, Li F, Krebs P, Futerman A, Addo M, Hardt C, Hoffmann D, Lang P, Lang K
FRONT IMMUNOL. 2020;11:607889.
Usp18 Expression in CD169+ Macrophages is Important for Strong Immune Response after Vaccination with VSV-EBOV
Friedrich S, Schmitz R, Bergerhausen M, Lang J, Cham L, Duhan V, Häussinger D, Hardt C, Addo M, Prinz M, Asano K, Lang P, Lang K
VACCINES-BASEL. 2020;8(1):.
Epitopes of Naturally Acquired and Vaccine-Induced Anti-Ebola Virus Glycoprotein Antibodies in Single Amino Acid Resolution
Heidepriem J, Krähling V, Dahlke C, Wolf T, Klein F, Addo M, Becker S, Loeffler F
BIOTECHNOL J. 2020;15(9):e2000069.
Relapsing cutaneous leishmaniasis in a patient requiring TNF-α-inhibitor Infliximab for Takayasu-arteritis: Case report and review of the literature
Heinemann M, Omansen T, Hennigs A, Völker K, Menz A, Addo M, Schmiedel S
TRAVEL MED INFECT DI. 2020;37:101700.
Significance of Anti-Nuclear Antibodies and Cryoglobulins in Patients with Acute and Chronic HEV Infection
Horvatits T, Schulze Zur Wiesch J, Polywka S, Buescher G, Lütgehetmann M, Hussey E, Horvatits K, Peine S, Haag F, Addo M, Lohse A, Weiler-Normann C, Pischke S
PATHOGENS. 2020;9(9):.
No link between male infertility and HEV genotype 3 infection
Horvatits T, Varwig-Janssen D, Schulze Zur Wiesch J, Lübke R, Reucher S, Frerk S, Addo M, Schneider S, Lohse A, Luetgehetmann M, Pischke S
GUT. 2020;69(6):1150-1151.
Scent dog identification of samples from COVID-19 patients - a pilot study
Jendrny P, Schulz C, Twele F, Meller S, von Köckritz-Blickwede M, Osterhaus A, Ebbers J, Pilchová V, Pink I, Welte T, Manns M, Fathi A, Ernst C, Addo M, Schalke E, Volk H
BMC INFECT DIS. 2020;20(1):536.
Targeting Endothelial Dysfunction in Eight Extreme-Critically Ill Patients with COVID-19 Using the Anti-Adrenomedullin Antibody Adrecizumab (HAM8101)
Karakas M, Jarczak D, Becker M, Roedl K, Addo M, Hein F, Bergmann A, Zimmermann J, Simon T, Marx G, Lütgehetmann M, Nierhaus A, Kluge S
BIOMOLECULES. 2020;10(8):.
Safety and immunogenicity of a modified vaccinia virus Ankara vector vaccine candidate for Middle East respiratory syndrome: an open-label, phase 1 trial
Koch T, Dahlke C, Fathi A, Kupke A, Krähling V, Okba N, Halwe S, Rohde C, Eickmann M, Volz A, Hesterkamp T, Jambrecina A, Borregaard S, Ly M, Zinser M, Bartels E, Poetsch J, Neumann R, Fux R, Schmiedel S, Lohse A, Haagmans B, Sutter G, Becker S, Addo M
LANCET INFECT DIS. 2020;20(7):827-838.
Ebola Virus Disease Survivors Show More Efficient Antibody Immunity than Vaccinees Despite Similar Levels of Circulating Immunoglobulins
Koch T, Rottstegge M, Ruibal P, Gomez-Medina S, Nelson E, Escudero-Pérez B, Pillny M, Ly M, Koundouno F, Bore J, Magassouba N, Dahlke C, Günther S, Carroll M, Addo M, Muñoz-Fontela C
VIRUSES-BASEL. 2020;12(9):.
Sustained response after remdesivir and convalescent plasma therapy in a B-cell depleted patient with protracted COVID-19
Malsy J, Veletzky L, Heide J, Hennigs A, Gil-Ibanez I, Stein A, Lütgehetmann M, Rosien U, Jasper D, Peine S, Hiller J, Haag F, Schmiedel S, Huber S, Jordan S, Addo M, Schulze Zur Wiesch J
CLIN INFECT DIS. 2020;73(11):e4020–e4024.
Rapid dose-dependent Natural Killer (NK) cell modulation and cytokine responses following human rVSV-ZEBOV Ebolavirus vaccination
Pejoski D, de Rham C, Martinez-Murillo P, Santoro F, Auderset F, Medaglini D, Pozzi G, Vono M, Lambert P, Huttner A, Haks M, Ottenhoff T, Villard J, Siegrist C
NPJ VACCINES. 2020;5(1):32.
Clinical evaluation of five different automated SARS-CoV-2 serology assays in a cohort of hospitalized COVID-19 patients
Pflüger L, Bannasch J, Brehm T, Pfefferle S, Hoffmann A, Nörz D, van der Meirschen M, Kluge S, Haddad M, Pischke S, Hiller J, Addo M, Lohse A, Wiesch J, Peine S, Aepfelbacher M, Lütgehetmann M
J CLIN VIROL. 2020;130:104549.
Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
Polack F, Thomas S, Kitchin N, Absalon J, Gurtman A, Lockhart S, Perez J, Perez Marc G, Moreira E, Zerbini C, Bailey R, Swanson K, Roychoudhury S, Koury K, Li P, Kalina W, Cooper D, Frenck Jr R, Hammitt L, Türeci Ö, Nell H, Schaefer A, Ünal S, Tresnan D, Mather S, Dormitzer P, Sahin U, Jansen K, Gruber W
NEW ENGL J MED. 2020;383(27):2603-2615.
Von den Toten lernen - neue Erkenntnisse zu Covid-19
Püschel K, Kluge S, Addo M, Aepfelbacher M
Hamb Ärztebl. 2020;73(06):34-36.
Next-Generation Sequencing of T and B Cell Receptor Repertoires from COVID-19 Patients Showed Signatures Associated with Severity of Disease
Schultheiß C, Paschold L, Simnica D, Mohme M, Willscher E, von Wenserski L, Scholz R, Wieters I, Dahlke C, Tolosa E, Sedding D, Ciesek S, Addo M, Binder M
IMMUNITY. 2020;53(2):442-455.e4.
Integration of microarray data and literature mining identifies a sex bias in DPP4+CD4+ T cells in HIV-1 infection
Stubbe H, Dahlke C, Rotheneder K, Stirner R, Roider J, Conca R, Seybold U, Bogner J, Addo M, Draenert R
PLOS ONE. 2020;15(9):e0239399.
COVID-19: Wo stehen wir heute?
von Bergwelt Baildon M, Addo M
DEUT MED WOCHENSCHR. 2020;145(15):1019.
Autopsy Findings and Venous Thromboembolism in Patients With COVID-19: A Prospective Cohort Study
Wichmann D, Sperhake J, Lütgehetmann M, Steurer S, Edler C, Heinemann A, Heinrich F, Mushumba H, Kniep I, Schröder A, Burdelski C, de Heer G, Nierhaus A, Frings D, Pfefferle S, Becker H, Bredereke-Wiedling H, de Weerth A, Paschen H, Sheikhzadeh-Eggers S, Stang A, Schmiedel S, Bokemeyer C, Addo M, Aepfelbacher M, Püschel K, Kluge S
ANN INTERN MED. 2020;173(4):268-277.
Frequent neurocognitive deficits after recovery from mild COVID-19
Woo M, Malsy J, Pöttgen J, Seddiq Zai S, Ufer F, Hadjilaou A, Schmiedel S, Addo M, Gerloff C, Heesen C, Schulze zur Wiesch J, Friese M
BRAIN COMMUN. 2020;2(2):fcaa205.
Polyclonal and convergent antibody response to Ebola virus vaccine rVSV-ZEBOV
Ehrhardt S, Zehner M, Krähling V, Cohen-Dvashi H, Kreer C, Elad N, Gruell H, Ercanoglu M, Schommers P, Gieselmann L, Eggeling R, Dahlke C, Wolf T, Pfeifer N, Addo M, Diskin R, Becker S, Klein F
NAT MED. 2019;25(10):1589-1600.
Recombinant vesicular stomatitis virus vector vaccines for WHO blueprint priority pathogens
Fathi A, Dahlke C, Addo M
HUM VACC IMMUNOTHER. 2019;15(10):2269-2285.
Brain magnetic resonance imaging in imported malaria
Frölich A, Tober-Lau P, Schönfeld M, Brehm T, Kurth F, Vinnemeier C, Addo M, Fiehler J, Rolling T
MALARIA J. 2019;18(1):74.
Rezidivierendes Erbrechen und Kopfschmerzen bei einem 26-jährigen Patienten
Heinemann M, Galaski J, Mager A, Ittrich H, Addo M, Jordan S
INTERNIST. 2019;60(7):756-760.
Transjugular Intrahepatic Portosystemic Shunt (TIPS) for primary and secondary prophylaxis of variceal bleeding in hepatic schistosomiasis
Kraef C, Arand J, Galaski J, Jordan S, Kluwe J, Lohse A, Addo M, Ramharter M, Schmiedel S
TRAVEL MED INFECT DI. 2019;30:130-132.
Management der saisonalen Influenza 2017/2018: Erfahrungen an einem deutschen Universitätsklinikum
Kraef C, van der Meirschen M, Wichmann D, Kutza M, Restemeyer C, Addo M, Lohse A, Schmiedel S, Kluge S, Schulze Zur Wiesch J
BUNDESGESUNDHEITSBLA. 2019;62(7):870-880.
Detectable Vesicular Stomatitis Virus (VSV)-Specific Humoral and Cellular Immune Responses Following VSV-Ebola Virus Vaccination in Humans
Poetsch J, Dahlke C, Zinser M, Kasonta R, Lunemann S, Rechtien A, Ly M, Stubbe H, Krähling V, Biedenkopf N, Eickmann M, Fehling S, Olearo F, Strecker T, Sharma P, Lang K, Lohse A, Schmiedel S, Becker S, Addo M
J INFECT DIS. 2019;219(4):556-561.
Immediate versus deferred antiretroviral therapy in HIV-infected patients presenting with acute AIDS-defining events (toxoplasmosis, Pneumocystis jirovecii-pneumonia): a prospective, randomized, open-label multicenter study (IDEAL-study)
Schäfer G, Hoffmann C, Arasteh K, Schürmann D, Stephan C, Jensen B, Stoll M, Bogner J, Faetkenheuer G, Rockstroh J, Klinker H, Härter G, Stöhr A, Degen O, Bibiza-Freiwald E, Hüfner A, Jordan S, Schulze Zur Wiesch J, Addo M, Lohse A, van Lunzen J, Schmiedel S
AIDS RES THER. 2019;16(1):34.
Determinants of post-malarial anemia in African children treated with parenteral artesunate
Scheu K, Adegnika A, Addo M, Ansong D, Cramer J, Fürst S, Kremsner P, Kurth F, Jacobs T, May J, Ramharter M, Sylverken J, Vinnemeier C, Agbenyega T, Rolling T
SCI REP-UK. 2019;9(1):18134.
Author Correction: Differential expression pattern of co-inhibitory molecules on CD4 T cells in uncomplicated versus complicated malaria.
Abel A, Steeg C, Aminkiah F, Addai-Mensah O, Addo M, Gagliani N, Casar C, Yar D, Owusu-Dabo E, Jacobs T, Mackroth M
SCI REP-UK. 2018;8(1):17587.
Differential expression pattern of co-inhibitory molecules on CD4(+) T cells in uncomplicated versus complicated malaria
Abel A, Steeg C, Aminkiah F, Addai-Mensah O, Addo M, Gagliani N, Casar C, Yar D, Owusu-Dabo E, Jacobs T, Mackroth M
SCI REP-UK. 2018;8(1):4789.
Ist die Welt ausreichend gerüstet für das nächste unbekannte Virus?
Addo M
Frankfurter Allgemeine Zeitung. 2018.
Tuberculous Tenosynovitis
Brehm T, Schmiedel S, Addo M
DTSCH ARZTEBL INT. 2018;115(42):714.
Epidemiology, clinical and laboratory features of 24 consecutive cases of leptospirosis at a German infectious disease center.
Brehm T, Schulze zur Wiesch J, Lütgehetmann M, Tappe D, Eisermann P, Lohse A, Addo M, Schmiedel S
INFECTION. 2018;46(6):847-853.
Dynamic changes of circulating miRNAs induced by the Ebola virus vaccine VSV-EBOV
Fischer T, Spohn M, Olearo F, Zinser M, Kasonta R, Stubbe H, Rechtien A, Ly M, Schmiedel S, Lohse A, Grundhoff A, Addo M, Dahlke C
VACCINE. 2018;36(46):7083-7094.
Determinants of antibody persistence across doses and continents after single-dose rVSV-ZEBOV vaccination for Ebola virus disease: an observational cohort study
Huttner A, Agnandji S, Combescure C, Fernandes J, Bache E, Kabwende L, Ndungu F, Brosnahan J, Monath T, Lemaître B, Grillet S, Botto M, Engler O, Portmann J, Siegrist D, Bejon P, Silvera P, Kremsner P, Siegrist C
LANCET INFECT DIS. 2018;18(7):738-748.
HEV-positive blood donations represent a relevant infection risk for immunosuppressed recipients
Westhölter D, Hiller J, Denzer U, Polywka S, Ayuk F, Rybczynski M, Horvatits T, Gundlach S, Blöcker J, Schulze Zur Wiesch J, Fischer N, Addo M, Peine S, Göke B, Lohse A, Lütgehetmann M, Pischke S
J HEPATOL. 2018;69(1):36-42.
Ebola-Impfstoff-Entwicklung: Im Krisenfall schnell, aber mit hohem Sicherheitsanspruch
Zinser M, Borregaard S, Dahlke C, Addo M
DTSCH ARZTEBL INT. 2018;115(Supplement: Perspektiven der Infektiologie):27-28.
Acute HIV-1 infection is associated with increased plasma levels of heme oxygenase-1 and presence of heme oxygenase-1-specific regulatory T cells
Angin M, Fathi A, King M, Ledoux M, Piechocka-Trocha A, Altfeld M, Addo M
AIDS. 2017;31(5):635-641.
Dose-dependent T-cell Dynamics and Cytokine Cascade Following rVSV-ZEBOV Immunization
Dahlke C, Kasonta R, Lunemann S, Krähling V, Zinser M, Biedenkopf N, Fehling S, Ly M, Rechtien A, Stubbe H, Olearo F, Borregaard S, Jambrecina A, Stahl F, Strecker T, Eickmann M, Lütgehetmann M, Spohn M, Schmiedel S, Lohse A, Becker S, Addo M
EBIOMEDICINE. 2017;19:107-118.
Comprehensive characterization of cellular immune responses following Ebola virus infection
Dahlke C, Lunemann S, Kasonta R, Kreuels B, Schmiedel S, Ly M, Fehling S, Strecker T, Becker S, Altfeld M, Sow A, Lohse A, Muñoz-Fontela C, Addo M
J INFECT DIS. 2017;215(2):287-292.
Systems Vaccinology Identifies an Early Innate Immune Signature as a Correlate of Antibody Responses to the Ebola Vaccine rVSV-ZEBOV
Rechtien A, Richert L, Lorenzo H, Martrus G, Hejblum B, Dahlke C, Kasonta R, Zinser M, Stubbe H, Matschl U, Lohse A, Krähling V, Eickmann M, Becker S, Thiébaut R, Altfeld M, Addo M
CELL REP. 2017;20(9):2251-2261.
Pre-travel advice at a crossroad: Medical preparedness of travellers to South and Southeast-Asia - The Hamburg Airport Survey
Rolling T, Mühlenpfordt M, Addo M, Cramer J, Vinnemeier C
TRAVEL MED INFECT DI. 2017;18:41-45.
Helminthic infections in returning travelers and migrants with eosinophilia: Diagnostic value of medical history, eosinophil count and IgE
Salzer H, Rolling T, Vinnemeier C, Tannich E, Schmiedel S, Addo M, Cramer J
TRAVEL MED INFECT DI. 2017;20:49-55.
Response to fever and utilization of standby emergency treatment (SBET) for malaria in travellers to Southeast Asia: a questionnaire-based cohort study
Vinnemeier C, Rothe C, Kreuels B, Addo M, Vygen-Bonnet S, Cramer J, Rolling T
MALARIA J. 2017;16(1):44.
Viren überlisten: Globale Virusinfektionen werden beherrschbar - aber neue Gefahren drohen
Addo M, Lohse A
2016. Erkenntnis, Wissenschaft und Gesellschaft. Buchmüller W, Jakobeit C (eds.). 1. ed. Springer-Verlag GmbH and Co. KG, 101-118.
Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe
Agnandji S, Huttner A, Zinser M, Njuguna P, Dahlke C, Fernandes J, Yerly S, Dayer J, Kraehling V, Kasonta R, Adegnika A, Altfeld M, Auderset F, Bache E, Biedenkopf N, Borregaard S, Brosnahan J, Burrow R, Combescure C, Desmeules J, Eickmann M, Fehling S, Finckh A, Goncalves A, Grobusch M, Hooper J, Jambrecina A, Kabwende A, Kaya G, Kimani D, Lell B, Lemaître B, Lohse A, Massinga-Loembe M, Matthey A, Mordmüller B, Nolting A, Ogwang C, Ramharter M, Schmidt-Chanasit J, Schmiedel S, Silvera P, Stahl F, Staines H, Strecker T, Stubbe H, Tsofa B, Zaki S, Fast P, Moorthy V, Kaiser L, Krishna S, Becker S, Kieny M, Bejon P, Kremsner P, Addo M, Siegrist C
NEW ENGL J MED. 2016;374(17):1647-60.
Molecular Diagnosis of Human Taenia martis Eye Infection
Koch T, Schoen C, Muntau B, Addo M, Ostertag H, Wiechens B, Tappe D
AM J TROP MED HYG. 2016;94(5):1055-7.
Acute Ebola virus disease patient treatment and health-related quality of life in health care professionals: A controlled study
Lehmann M, Brünahl C, Addo M, Becker S, Schmiedel S, Lohse A, Schramm C, Löwe B
J PSYCHOSOM RES. 2016;83:69-74.
Rapid-Antigen Test Negative Malaria in a Traveler Returning From Thailand, Molecularly Diagnosed as Plasmodium knowlesi
Mackroth M, Tappe D, Tannich E, Addo M, Rothe C
OPEN FORUM INFECT DI. 2016;3(1):ofw039.
Sharp increase of imported Plasmodium vivax malaria seen in migrants from Eritrea in Hamburg, Germany
Roggelin L, Tappe D, Noack B, Addo M, Tannich E, Rothe C
MALARIA J. 2016;2016(15):325.
Unique human immune signature of Ebola virus disease in Guinea
Ruibal P, Oestereich L, Lüdtke A, Becker-Ziaja B, Wozniak D, Kerber R, Korva M, Cabeza-Cabrerizo M, Bore J, Koundouno F, Duraffour S, Weller R, Thorenz A, Cimini E, Viola D, Agrati C, Repits J, Afrough B, Cowley L, Ngabo D, Hinzmann J, Mertens M, Vitoriano I, Logue C, Boettcher J, Pallasch E, Sachse A, Bah A, Nitzsche K, Kuisma E, Michel J, Holm T, Zekeng E, García-Dorival I, Wölfel R, Stoecker K, Fleischmann E, Strecker T, Di Caro A, Avšič-Županc T, Kurth A, Meschi S, Mély S, Newman E, Bocquin A, Kis Z, Kelterbaum A, Molkenthin P, Carletti F, Portmann J, Wolff S, Castilletti C, Schudt G, Fizet A, Ottowell L, Herker E, Jacobs T, Kretschmer B, Severi E, Ouedraogo N, Lago M, Negredo A, Franco L, Anda P, Schmiedel S, Kreuels B, Wichmann D, Addo M, Lohse A, De Clerck H, Nanclares C, Jonckheere S, Van Herp M, Sprecher A, Xiaojiang G, Carrington M, Miranda O, Castro C, Gabriel M, Drury P, Formenty P, Diallo B, Koivogui L, Magassouba N, Carroll M, Günther S, Muñoz-Fontela C
NATURE. 2016;533(7601):100-4.
Medizinische Versorgung von Flüchtlingen: Eine Fallserie des Universitätsklinikums Hamburg-Eppendorf
Sothmann P, Schmedt auf der Günne N, Addo M, Lohse A, Schmiedel S
DEUT MED WOCHENSCHR. 2016;141(1):34-37.
Medizinische Versorgung von Flüchtlingen – Eine Fallserie des Universitätsklinikums Hamburg-Eppendorf
Sothmann P, Schmedt auf der Günne N, Roggelin L, Kreuels B, Rothe C, Addo M, Lohse A, Schulze zur Wiesch J, Schmiedel S
FLUGMEDIZIN TROPENME. 2016;23(1):45-49.
Tropheryma whipplei in children with diarrhoea in rural Ghana
Vinnemeier C, Klupp E, Krumkamp R, Rolling T, Fischer N, Owusu-Dabo E, Addo M, Adu-Sarkodie Y, Käsmaier J, Aepfelbacher M, Cramer J, May J, Tannich E
CLIN MICROBIOL INFEC. 2016;22(1):65.e1 - 65.e3.
Geschlechtsunterschiede bei Infektionserkrankungen
Beisel C, Lunzen J, Lohse A, Addo M, Altfeld M
DEUT MED WOCHENSCHR. 2015;140(18):1385-90.
Comparison of autochthonous and imported cases of hepatitis A or hepatitis E
Hartl J, Kreuels B, Polywka S, Addo M, Lütgehetmann M, Dandri-Petersen M, Dammermann W, Sterneck M, Lohse A, Pischke S
Z GASTROENTEROL. 2015;53(7):639-643.
Severe Ebola virus infection complicated by gram-negative septicemia
Kreuels B, Addo M, Schmiedel S
NEW ENGL J MED. 2015;372(14):1377.
Ebola and psychological stress of health care professionals
Lehmann M, Brünahl C, Löwe B, Addo M, Schmiedel S, Lohse A, Schramm C
EMERG INFECT DIS. 2015;21(5):913-914.
Tim-3 blocking rescue macrophage and T cell function against Mycobacterium tuberculosis infection in HIV+ patients
Sada-Ovalle I, Ocaña-Guzman R, Pérez-Patrigeón S, Chávez-Galán L, Sierra-Madero J, Torre-Bouscoulet L, Addo M, Addo M
J INT AIDS SOC. 2015;18(1):20078.
Ex vivo cytosolic delivery of functional macromolecules to immune cells
Sharei A, Trifonova R, Jhunjhunwala S, Hartoularos G, Eyerman A, Lytton-Jean A, Angin M, Sharma S, Poceviciute R, Mao S, Heimann M, Liu S, Talkar T, Khan O, Addo M, von Andrian U, Anderson D, Langer R, Lieberman J, Jensen K
PLOS ONE. 2015;10(4):e0118803.
Sex-based differences in HIV type 1 pathogenesis
Addo M, Altfeld M
J INFECT DIS. 2014;209 Suppl 3(Suppl 3):S86-92.
Regulatory T cells expanded from HIV-1-infected individuals maintain phenotype, TCR repertoire and suppressive capacity
Angin M, Klarenbeek P, King M, Sharma S, Moodley E, Rezai A, Piechocka-Trocha A, Toth I, Chan A, Goulder P, Ndung'u T, Kwon D, Addo M
PLOS ONE. 2014;9(2):e86920.
HIV-1 infection impairs regulatory T-cell suppressive capacity on a per-cell basis
Angin M, Sharma S, King M, Murooka T, Ghebremichael M, Mempel T, Walker B, Bhasin M, Addo M
J INFECT DIS. 2014;210(6):899-903.
A dead-end host: is there a way out? A position piece on the ebola virus outbreak by the international union of immunology societies
Gray C, Addo M, Schmidt R
FRONT IMMUNOL. 2014;5:562.
A case of severe Ebola virus infection complicated by gram-negative septicemia
Kreuels B, Wichmann D, Emmerich P, Schmidt-Chanasit J, Heer G, Kluge S, Sow A, Renné T, Günther S, Lohse A, Addo M, Schmiedel S
NEW ENGL J MED. 2014;371(25):2394-401.
New tools to expand regulatory T cells from HIV-1-infected individuals
Angin M, King M, Addo M
JOVE-J VIS EXP. 2013;(75):e50244.
Dysregulated Tim-3 expression on natural killer cells is associated with increased Galectin-9 levels in HIV-1 infection
Jost S, Moreno-Nieves U, Garcia-Beltran W, Rands K, Reardon J, Toth I, Piechocka-Trocha A, Altfeld M, Addo M
RETROVIROLOGY. 2013;10:74.
Temporal effect of HLA-B*57 on viral control during primary HIV-1 infection
Vaidya S, Streeck H, Beckwith N, Ghebremichael M, Pereyra F, Kwon D, Addo M, Rychert J, Routy J, Jessen H, Kelleher A, Hecht F, Sekaly R, Carrington M, Walker B, Allen T, Rosenberg E, Altfeld M
RETROVIROLOGY. 2013;10:139.
Identification of HIV-1-specific regulatory T-cells using HLA class II tetramers.
Angin M, King M, Altfeld M, Walker B, Wucherpfennig K, Addo M
AIDS. 2012;26(16):2112-2115.
Preserved function of regulatory T cells in chronic HIV-1 infection despite decreased numbers in blood and tissue.
Angin M, Kwon D, Streeck H, Wen F, King M, Rezai A, Law K, Hongo T, Pyo A, Piechocka-Trocha A, Toth I, Pereyra F, Ghebremichael M, Rodig S, Milner D, Richter J, Altfeld M, Kaufmann D, Walker B, Addo M
J INFECT DIS. 2012;205(10):1495-1500.
Regulatory T cell frequencies do not correlate with breadth or magnitude of HIV-1-specific T cell responses.
Angin M, Streeck H, Wen F, King M, Pereyra F, Altfeld M, Walker B, Addo M
AIDS RES HUM RETROV. 2012;28(8):749-751.
Primary HIV-1 infection is associated with increased plasma levels of heme-oxygenase-1 (HO-1) and presence of HO-1-specific regulatory T cells.
Fathi A, Angin M, King M, Piechocka-Trocha A, Altfeld M, Walker B, Addo M
2012. 19th Conference on Retroviruses and Opportunistic Infections, Seattle, WA, USA. .
CD4+ CD25+ regulatory T cells impair HIV-1-specific CD4 T cell responses by upregulating interleukin-10 production in monocytes.
Kwon D, Angin M, Hongo T, Law K, Johnson J, Porichis F, Hart M, Pavlik D, Tighe D, Kavanagh D, Streeck H, Addo M, Kaufmann D
J VIROL. 2012;86(12):6586-6594.
Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion.
Rangachari M, Zhu C, Sakuishi K, Xiao S, Karman J, Chen A, Angin M, Wakeham A, Greenfield E, Sobel R, Okada H, McKinnon P, Mak T, Addo M, Anderson A, Kuchroo V
NAT MED. 2012;18(9):1394-1400.
Lack of detectable HIV-1-specific CD8(+) T cell responses in Zambian HIV-1-exposed seronegative partners of HIV-1-positive individuals.
Addo M, Altfeld M, Brainard D, Rathod A, Piechocka-Trocha A, Fideli U, Mulenga J, Shutes E, Alvino D, Hunter E, Allen S, Walker B
J INFECT DIS. 2011;203(2):258-262.
Increased plasma levels of hemoxygenase-1 (HO-1) and presence of HO-1-specific regulatory T cells in acute HIV-1 infection
Angin M, Fathi A, King M, Addo M
2011. AIDS Vaccine Conference 2011, Bangkok, Thailand. .
Impact of heme oxygenase-1 specific CD8+ regulatory T cells on HIV-1 immunity
Fathi A, Angin M, King M, Addo M
2011. Scientific Advisory Committee 2011 Poster Session, Massachusetts General Hospital, Boston, MA, USA. .
Infrequent recovery of HIV from but robust exogenous infection of activated CD4(+) T cells in HIV elite controllers.
Julg B, Pereyra F, Buzón M, Piechocka-Trocha A, Clark M, Baker B, Lian J, Miura T, Martinez-Picado J, Addo M, Walker B
CLIN INFECT DIS. 2010;51(2):233-238.
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.
Study I, Pereyra F, Jia X, McLaren P, Telenti A, Bakker d, Paul I, Walker B, Ripke S, Brumme C, Pulit S, Carrington M, Kadie C, Carlson J, Heckerman D, Graham R, Plenge R, Deeks S, Gianniny L, Crawford G, Sullivan J, Gonzalez E, Davies L, Camargo A, Moore J, Beattie N, Gupta S, Crenshaw A, Burtt N, Guiducci C, Gupta N, Gao X, Qi Y, Yuki Y, Piechocka-Trocha A, Cutrell E, Rosenberg R, Moss K, Lemay P, O'Leary J, Schaefer T, Verma P, Toth I, Block B, Baker B, Rothchild A, Lian J, Proudfoot J, Alvino D, Addo M, Addo M, Allen T, Altfeld M, Henn M, Sylvie L, Streeck H, Haas D, Kuritzkes D, Robbins G, Shafer R, Gulick R, Shikuma C, Haubrich R, Riddler S, Sax P, Daar E, Ribaudo H, Agan B, Agarwal S, Ahern R, Allen B, Altidor S, Altschuler E, Ambardar S, Anastos K, Anderson B, Anderson V, Andrady U, Antoniskis D, Bangsberg D, Barbaro D, Barrie W, Bartczak J, Barton S, Basden P, Basgoz N, Bazner S, Bellos N, Benson A, Berger J, Bernard N, Bernard A, Birch C, Bodner S, Bolan R, Boudreaux E, Bradley M, Braun J, Brndjar J, Brown S, Brown K, Brown S, Burack J, Bush L, Cafaro V, Campbell O, Campbell J, Carlson R, Carmichael J, Casey K, Cavacuiti C, Celestin G, Chambers S, Chez N, Chirch L, Cimoch P, Cohen D, Cohn L, Conway B, Cooper D, Cornelson B, Cox D, Cristofano M, Cuchural G, Czartoski J, Dahman J, Daly J, Davis B, Davis K, Davod S, DeJesus E, Dietz C, Dunham E, Dunn M, Ellerin T, Eron J, Fangman J, Farel C, Ferlazzo H, Fidler S, Fleenor-Ford A, Frankel R, Freedberg K, French N, Fuchs J, Fuller J, Gaberman J, Gallant J, Gandhi R, Garcia E, Garmon D, Gathe J, Gaultier C, Gebre W, Gilman F, Gilson I, Goepfert P, Gottlieb M, Goulston C, Groger R, Gurley T, Haber S, Hardwicke R, Hardy W, Harrigan P, Hawkins T, Heath S, Hecht F, Henry W, Hladek M, Hoffman R, Horton J, Hsu R, Huhn G, Hunt P, Hupert M, Illeman M, Jaeger H, Jellinger R, John M, Johnson J, Johnson K, Johnson H, Johnson K, Joly J, Jordan W, Kauffman C, Khanlou H, Killian R, Kim A, Kim D, Kinder C, Kirchner J, Kogelman L, Kojic E, Korthuis P, Kurisu W, Kwon D, LaMar M, Lampiris H, Lanzafame M, Lederman M, Lee D, Lee J, Lee M, Lee E, Lemoine J, Levy J, Llibre J, Liguori M, Little S, Liu A, Lopez A, Loutfy M, Loy D, Mohammed D, Man A, Mansour M, Marconi V, Markowitz M, Marques R, Martin J, Martin H, Mayer K, McElrath M, McGhee T, McGovern B, McGowan K, McIntyre D, Mcleod G, Menezes P, Mesa G, Metroka C, Meyer-Olson D, Miller A, Montgomery K, Mounzer K, Nagami E, Nagin I, Nahass R, Nelson M, Nielsen C, Norene D, O'Connor D, Ojikutu B, Okulicz J, Oladehin O, Oldfield E, Olender S, Ostrowski M, Owen W, Pae E, Parsonnet J, Pavlatos A, Perlmutter A, Pierce M, Pincus J, Pisani L, Price L, Proia L, Prokesch [
SCIENCE. 2010;330(6010):1551-1557.
The magnitude and breadth of hepatitis C virus-specific CD8+ T cells depend on absolute CD4+ T-cell count in individuals coinfected with HIV-1
Kim A, Lauer G, Ouchi K, Addo M, Lucas M, Schulze Zur Wiesch J, Timm J, Boczanowski M, Duncan J, Wurcel A, Casson D, Chung R, Draenert R, Klenerman P, Walker B
BLOOD. 2005;105(3):1170-8.
Vpr is preferentially targeted by CTL during HIV-1 infection
J IMMUNOL. 2001;167(5):2743-52.
The HIV-1 regulatory proteins Tat and Rev are frequently targeted by cytotoxic T lymphocytes derived from HIV-1-infected individuals
Addo M, Altfeld M, Rosenberg E, Eldridge R, Philips M, Habeeb K, Khatri A, Brander C, Robbins G, Mazzara G, Goulder P, Walker B
P NATL ACAD SCI USA. 2001;98(4):1781-6.
Identification of novel HLA-A2-restricted human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte epitopes predicted by the HLA-A2 supertype peptide-binding motif
Altfeld M, Livingston B, Reshamwala N, Nguyen P, Addo M, Shea A, Newman M, Fikes J, Sidney J, Wentworth P, Chesnut R, Eldridge R, Rosenberg E, Robbins G, Brander C, Sax P, Boswell S, Flynn T, Buchbinder S, Goulder P, Walker B, Sette A, Kalams S
J VIROL. 2001;75(3):1301-11.
Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection
Altfeld M, Rosenberg E, Shankarappa R, Mukherjee J, Hecht F, Eldridge R, Addo M, Poon S, Phillips M, Robbins G, Sax P, Boswell S, Kahn J, Brander C, Goulder P, Levy J, Mullins J, Walker B
J EXP MED. 2001;193(2):169-80.
Rapid definition of five novel HLA-A*3002-restricted human immunodeficiency virus-specific cytotoxic T-lymphocyte epitopes by elispot and intracellular cytokine staining assays
Goulder P, Addo M, Altfeld M, Rosenberg E, Tang Y, Govender U, Mngqundaniso N, Annamalai K, Vogel T, Hammond M, Bunce M, Coovadia H, Walker B
J VIROL. 2001;75(3):1339-47.
Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection
Goulder P, Altfeld M, Rosenberg E, Nguyen T, Tang Y, Eldridge R, Addo M, He S, Mukherjee J, Phillips M, Bunce M, Kalams S, Sekaly R, Walker B, Brander C
J EXP MED. 2001;193(2):181-94.
Evolution and transmission of stable CTL escape mutations in HIV infection
Goulder P, Brander C, Tang Y, Tremblay C, Colbert R, Addo M, Rosenberg E, Nguyen T, Allen R, Trocha A, Altfeld M, He S, Bunce M, Funkhouser R, Pelton S, Burchett S, McIntosh K, Korber B, Walker B
NATURE. 2001;412(6844):334-8.
T(H)1 to T(H)2 shift of cytokines in peripheral blood of HIV-infected patients is detectable by reverse transcriptase polymerase chain reaction but not by enzyme-linked immunosorbent assay under nonstimulated conditions
Altfeld M, Addo M, Kreuzer K, Rockstroh J, Dumoulin F, Schliefer K, Leifeld L, Sauerbruch T, Spengler U
JAIDS-J ACQ IMM DEF. 2000;23(4):287-94.
Identification of dominant optimal HLA-B60- and HLA-B61-restricted cytotoxic T-lymphocyte (CTL) epitopes: rapid characterization of CTL responses by enzyme-linked immunospot assay
Altfeld M, Trocha A, Eldridge R, Rosenberg E, Phillips M, Addo M, Sekaly R, Kalams S, Burchett S, McIntosh K, Walker B, Goulder P
J VIROL. 2000;74(18):8541-9.
Influence of protease inhibitor therapy on lipoprotein metabolism
Berthold H, Parhofer K, Ritter M, Addo M, Wasmuth J, Schliefer K, Spengler U, Rockstroh J
J INTERN MED. 1999;246(6):567-75.
Reactivation of hepatitis B in a long-term anti-HBs-positive patient with AIDS following lamivudine withdrawal
Altfeld M, Rockstroh J, Addo M, Kupfer B, Pult I, Will H, Spengler U
J HEPATOL. 1998;29(2):306-9.
Transmission of oral Candida albicans strains between HIV-positive patients
Boerlin P, Addo M, Boerlin-Petzold F, Durussel C, Pagani J, Chave J, Bille J
LANCET. 1995;345(8956):1052-3.
Cluster of oral atypical Candida albicans isolates in a group of human immunodeficiency virus-positive drug users
Boerlin P, Boerlin-Petzold F, Durussel C, Addo M, Pagani J, Chave J, Bille J
J CLIN MICROBIOL. 1995;33(5):1129-35.
Letzte Aktualisierung aus dem FIS: 13.12.2024 - 02:59 Uhr