Technology platforms for genetic modification

  • Genome editing platform

    Based on the CRISPR/Cas9 bases genome editing technology different applications can be used. Service is provided during project planning, strategy design, genotyping/ colony maintenance and injection. The service is available by scientific cooperation. For details feel free to contact:

    Prof. Dr. Boris Fehse

    Department of Stem Cell Transplantation

    +49 (0) 40 7410 - 55518

  • Isotope lab & irradiation core facility

    For researchers an isotope lab and an irradiation facility are available on UKE campus. Both are run by the Vice Deanery for Research. For further details and guidelines please follow the links.

    Isotope lab facility

    Irradiation facility

  • Radiobiology platform

    In vitro X-irradiations and assays for clonogenic cell survival, chromosomal aberrations as well as DNA damage & repair, signalling and cell cycle/replication dynamics are available through scientific collaboration at the Laboratory of Radiobiology & Experimental Radiation Oncology .


  • Small animal x-irradiation platform

    The recently established Precision X-Ray “SmART+” facility enables the precise locally ablative irradiation of tumors in small animal models. Cross sectional imaging with two different µCT imaging modalities (50µm and 20µm spatial resolution), several collimators for beam shaping, Monte-Carlo-based treatment planning and a high precision treatment table allow us to mimic the clinical image-guided radiotherapy setting. Furthermore, bioluminescence imaging in therapy position is possible, which allows functional tumor imaging.


    PD Dr. Dr. Thorsten Frenzel

    Department of Radiotherapy

    +49 (0) 40 7410 - 54031

  • Transgenic core facility

    This core facility is located at the Center for Molecular Neurobiology Hamburg (ZMNH).

    For further details please contact:

    ZMNH Core facility for transgenic mice

    +49 (0) 40 7410 - 56663

    Webiste of this core unit

  • Vector core facilities

    This core facility is run by the Vice Deneary for Research. For contact and further details about the service please follow the LINK

  • Xenograft tumor models platform

    This technology platform is provided by the Department of Anatomy and Experimental Morphology. For details and the offered service and conditions of possible scientific collaboration please contact:

    Prof. Dr. Tobias Lange

    Department of Anatomy and Experimental Morphology