- Head of scientific working group
Areas of expertise
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Oncology
Awards
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2021: Dr. Hans Messer-Foundation Award
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2018: Athene Young Investigator Award 2018, Technische Universität Darmstadt
Publications
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
Welsh J, Goberdhan D, O'Driscoll L, Buzas E, Blenkiron C, Bussolati B, Cai H, Di Vizio D, Driedonks T, Erdbrügger U, Falcon-Perez J, Fu Q, Hill A, Lenassi M, Lim S, Mahoney M, Mohanty S, Möller A, Nieuwland R, Ochiya T, Sahoo S, Torrecilhas A, Zheng L, Zijlstra A, Abuelreich S, Bagabas R, Bergese P, Bridges E, Brucale M, Burger D, Carney R, Cocucci E, Crescitelli R, Hanser E, Harris A, Haughey N, Hendrix A, Ivanov A, Jovanovic-Talisman T, Kruh-Garcia N, Ku'ulei-Lyn Faustino V, Kyburz D, Lässer C, Lennon K, Lötvall J, Maddox A, Martens-Uzunova E, Mizenko R, Newman L, Ridolfi A, Rohde E, Rojalin T, Rowland A, Saftics A, Sandau U, Saugstad J, Shekari F, Swift S, Ter-Ovanesyan D, Tosar J, Useckaite Z, Valle F, Varga Z, van der Pol E, van Herwijnen M, Wauben M, Wehman A, Williams S, Zendrini A, Zimmerman A, Théry C, Witwer K
J EXTRACELL VESICLES. 2024;13(2):e12404.
Novel insights into the isolation of extracellular vesicles by anion exchange chromatography
Koch L, Best T, Wüstenhagen E, Adrian K, Rammo O, Saul M
FRONT BIOENG BIOTECH. 2023;11:1298892.
The multiple functions of miR-574-5p in the neuroblastoma tumor microenvironment
Proestler E, Donzelli J, Nevermann S, Breitwieser K, Koch L, Best T, Fauth M, Wickström M, Harter P, Kogner P, Lavieu G, Larsson K, Saul M
FRONT PHARMACOL. 2023;14:1183720.
Detailed Characterization of Small Extracellular Vesicles from Different Cell Types Based on Tetraspanin Composition by ExoView R100 Platform
Breitwieser K, Koch L, Tertel T, Proestler E, Burgers L, Lipps C, Adjaye J, Fürst R, Giebel B, Saul M
INT J MOL SCI. 2022;23(15):8544.
Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer
Donzelli J, Proestler E, Riedel A, Nevermann S, Hertel B, Guenther A, Gattenlöhner S, Savai R, Larsson K, Saul M
J EXTRACELL VESICLES. 2021;10(12):e12143.
Proteomics-Based Characterization of miR-574-5p Decoy to CUGBP1 Suggests Specificity for mPGES-1 Regulation in Human Lung Cancer Cells
Emmerich A, Wellstein J, Ossipova E, Baumann I, Lengqvist J, Kultima K, Jakobsson P, Steinhilber D, Saul M
FRONT PHARMACOL. 2020;11:196.
Standardisierte mikroRNA-Analytik - die große Chance für Biomarkerstudien?
Fauth M, Saul M
BIOspektrum. 2020;26:621–623.
Extracellular miR-574-5p Induces Osteoclast Differentiation via TLR 7/8 in Rheumatoid Arthritis
Hegewald A, Breitwieser K, Ottinger S, Mobarrez F, Korotkova M, Rethi B, Jakobsson P, Catrina A, Wähämaa H, Saul M
FRONT IMMUNOL. 2020;11:585282.
Validation of extracellular miRNA quantification in blood samples using RT-qPCR
Fauth M, Hegewald A, Schmitz L, Krone D, Saul M
FASEB BIOADV. 2019;1(8):481-492.
miR-574-5p as RNA decoy for CUGBP1 stimulates human lung tumor growth by mPGES-1 induction
Saul M, Baumann I, Bruno A, Emmerich A, Wellstein J, Ottinger S, Contursi A, Dovizio M, Donnini S, Tacconelli S, Raouf J, Idborg H, Stein S, Korotkova M, Savai R, Terzuoli E, Sala G, Seeger W, Jakobsson P, Patrignani P, Suess B, Steinhilber D
FASEB J. 2019;33(6):6933-6947.
Regulation of Eicosanoid Pathways by MicroRNAs
Saul M, Emmerich A, Steinhilber D, Suess B
FRONT PHARMACOL. 2019;10:824.
Mass Spectrometry-Based Proteomics Approach Characterizes the Dual Functionality of miR-328 in Monocytes
Saul M, Hegewald A, Emmerich A, Ossipova E, Vogel M, Baumann I, Kultima K, Lengqivst J, Steinhilber D, Jakobsson P
FRONT PHARMACOL. 2019;10:640.
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
Théry C, Witwer K, Aikawa E, Alcaraz M, Anderson J, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith G, Ayre D, Bach J, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer N, Baxter A, Bebawy M, Beckham C, Bedina Zavec A, Benmoussa A, Berardi A, Bergese P, Bielska E, Blenkiron C, Bobis-Wozowicz S, Boilard E, Boireau W, Bongiovanni A, Borràs F, Bosch S, Boulanger C, Breakefield X, Breglio A, Brennan M, Brigstock D, Brisson A, Broekman M, Bromberg J, Bryl-Górecka P, Buch S, Buck A, Burger D, Busatto S, Buschmann D, Bussolati B, Buzás E, Byrd J, Camussi G, Carter D, Caruso S, Chamley L, Chang Y, Chen C, Chen S, Cheng L, Chin A, Clayton A, Clerici S, Cocks A, Cocucci E, Coffey R, Cordeiro-da-Silva A, Couch Y, Coumans F, Coyle B, Crescitelli R, Criado M, D'Souza-Schorey C, Das S, Datta Chaudhuri A, de Candia P, De Santana E, De Wever O, Del Portillo H, Demaret T, Deville S, Devitt A, Dhondt B, Di Vizio D, Dieterich L, Dolo V, Dominguez Rubio A, Dominici M, Dourado M, Driedonks T, Duarte F, Duncan H, Eichenberger R, Ekström K, El Andaloussi S, Elie-Caille C, Erdbrügger U, Falcón-Pérez J, Fatima F, Fish J, Flores-Bellver M, Försönits A, Frelet-Barrand A, Fricke F, Fuhrmann G, Gabrielsson S, Gámez-Valero A, Gardiner C, Gärtner K, Gaudin R, Gho Y, Giebel B, Gilbert C, Gimona M, Giusti I, Goberdhan D, Görgens A, Gorski S, Greening D, Gross J, Gualerzi A, Gupta G, Gustafson D, Handberg A, Haraszti R, Harrison P, Hegyesi H, Hendrix A, Hill A, Hochberg F, Hoffmann K, Holder B, Holthofer H, Hosseinkhani B, Hu G, Huang Y, Huber V, Hunt S, Ibrahim A, Ikezu T, Inal J, Isin M, Ivanova A, Jackson H, Jacobsen S, Jay S, Jayachandran M, Jenster G, Jiang L, Johnson S, Jones J, Jong A, Jovanovic-Talisman T, Jung S, Kalluri R, Kano S, Kaur S, Kawamura Y, Keller E, Khamari D, Khomyakova E, Khvorova A, Kierulf P, Kim K, Kislinger T, Klingeborn M, Klinke D, Kornek M, Kosanović M, Kovács Á, Krämer-Albers E, Krasemann S, Krause M, Kurochkin I, Kusuma G, Kuypers S, Laitinen S, Langevin S, Languino L, Lannigan J, Lässer C, Laurent L, Lavieu G, Lázaro-Ibáñez E, Le Lay S, Lee M, Lee Y, Lemos D, Lenassi M, Leszczynska A, Li I, Liao K, Libregts S, Ligeti E, Lim R, Lim S, Linē A, Linnemannstöns K, Llorente A, Lombard C, Lorenowicz M, Lörincz Á, Lötvall J, Lovett J, Lowry M, Loyer X, Lu Q, Lukomska B, Lunavat T, Maas S, Malhi H, Marcilla A, Mariani J, Mariscal J, Martens-Uzunova E, Martin-Jaular L, Martinez M, Martins V, Mathieu M, Mathivanan S, Maugeri M, McGinnis L, McVey M, Meckes D, Meehan K, Mertens I, Minciacchi V, Möller A, Møller Jørgensen M, Morales-Kastresana A, Morhayim J, Mullier F, Muraca M, Musante L, Mussack V, Muth D, Myburgh K, Najrana T, Nawaz M, Nazarenko I, Nejsum P, Neri C, Neri T, Nieuwland R, Nimrichter L, Nolan J, Nolte-'t Hoen E, Noren Hooten N, O'Driscoll L, O'Grady T, O'Loghlen A, Ochiya T, Olivier M, Ortiz A, Ortiz L, Osteikoetxea X, Østergaard O, Ostrowski M, Park J, Pegtel D, Peinado H, Perut F, Pfaffl M, Phinney D, Pieters B, Pink R, Pisetsky D, Pogge von Strandmann E, Polakovicova I, Poon I, Powell B, Prada I, Pulliam L, Quesenberry P, Radeghieri A, Raffai R, Raimondo S, Rak J, Ramirez M, Raposo G, Rayyan M, Regev-Rudzki N, Ricklefs F, Robbins P, Roberts D, Rodrigues S, Rohde E, Rome S, Rouschop K, Rughetti A, Russell A, Saá P, Sahoo S, Salas-Huenuleo E, Sánchez C, Saugstad J, Saul M, Schiffelers R, Schneider R, Schøyen T, Scott A, Shahaj E, Sharma S, Shatnyeva O, Shekari F, Shelke G, Shetty A, Shiba K, Siljander P, Silva A, Skowronek A, Snyder O, Soares R, Sódar B, Soekmadji C, Sotillo J, Stahl P, Stoorvogel W, Stott S, Strasser E, Swift S, Tahara H, Tewari M, Timms K, Tiwari S, Tixeira R, Tkach M, Toh W, Tomasini R, Torrecilhas A, Tosar J, Toxavidis V, Urbanelli L, Vader P, van Balkom B, van der Grein S, Van Deun J, van Herwijnen M, Van Keuren-Jensen K, van Niel G, van Royen M, van Wijnen A, Vasconcelos M, Vechetti I, Veit T, Vella L, Velot É, Verweij F, Vestad B, Viñas J, Visnovitz T, Vukman K, Wahlgren J, Watson D, Wauben M, Weaver A, Webber J, Weber V, Wehman A, Weiss D, Welsh J, Wendt S, Wheelock A, Wiener Z, Witte L, Wolfram J, Xagorari A, Xander P, Xu J, Yan X, Yáñez-Mó M, Yin H, Yuana Y, Zappulli V, Zarubova J, Žėkas V, Zhang J, Zhao Z, Zheng L, Zheutlin A, Zickler A, Zimmermann P, Zivkovic A, Zocco D, Zuba-Surma E
J EXTRACELL VESICLES. 2018;7(1):1535750.
Characterization and cellular localization of human 5-lipoxygenase and its protein isoforms 5-LOΔ13, 5-LOΔ4 and 5-LOp12
Ball A, Beilstein K, Wittmann S, Sürün D, Saul M, Schnütgen F, Flamand N, Capelo R, Kahnt A, Frey H, Schaefer L, Marschalek R, Häfner A, Steinhilber D
BBA-MOL CELL BIOL L. 2017;1862(5):561-571.
Acetylsalicylic acid as platelet aggregation inhibitor
Bruno A, Dovizio M, Saul M, Tacconelli S, Patrignani P
Pharmakon. 2017.
TGFβ/SMAD signalling modulates MLL and MLL-AF4 mediated 5-lipoxygenase promoter activation
Saul M, Groher F, Hegewald A, Müller-McNicoll M, Marschalek R, Suess B, Steinhilber D
PROSTAG OTH LIPID M. 2017;133:60-67.
Identification and Characterization of a New Protein Isoform of Human 5-Lipoxygenase
Häfner A, Beilstein K, Graab P, Ball A, Saul M, Hofmann B, Steinhilber D
PLOS ONE. 2016;11(11):e0166591.
UPF1 regulates myeloid cell functions and S100A9 expression by the hnRNP E2/miRNA-328 balance
Saul M, Stein S, Grez M, Jakobsson P, Steinhilber D, Suess B
SCI REP-UK. 2016;6:31995.
MicroRNAs-novel therapeutic targets of eicosanoid signalling
Ochs M, Steinhilber D, Suess B
BASIC CLIN PHARMACOL. 2014;114(1):92-96.
5-lipoxygenase mRNA and protein isoforms
Ochs M, Suess B, Steinhilber D
BASIC CLIN PHARMACOL. 2014;114(1):78-82.
Mass spectrometry-based proteomics identifies UPF1 as a critical gene expression regulator in MonoMac 6 cells
Ochs M, Ossipova E, Oliynyk G, Steinhilber D, Suess B, Jakobsson P
J PROTEOME RES. 2013;12(6):2622-2629.
Post-transcriptional regulation of 5-lipoxygenase mRNA expression via alternative splicing and nonsense-mediated mRNA decay
Ochs M, Sorg B, Pufahl L, Grez M, Suess B, Steinhilber D
PLOS ONE. 2012;7(2):e31363.
MicroRNA Involved in Inflammation: Control of Eicosanoid Pathway
Ochs M, Steinhilber D, Suess B
FRONT PHARMACOL. 2011;2:39.
Isothiocyanate sulforaphane inhibits protooncogenic ornithine decarboxylase activity in colorectal cancer cells via induction of the TGF-β/Smad signaling pathway
Kaminski B, Loitsch S, Ochs M, Reuter K, Steinhilber D, Stein J, Ulrich S
MOL NUTR FOOD RES. 2010;54(10):1486-1496.
Letzte Aktualisierung aus dem FIS: 10.11.2024 - 10:39 Uhr