Nathaniel Melling
Priv.-Doz. Dr. med.
Nathaniel Melling
  • Senior physician
  • Medical Specialist in General Surgery
  • Medical Specialist in Visceral Surgery
  • Special Surgery Intensive Care
  • Special Visceral Surgery
Working area

Location

Main Building O10 , 2nd Floor, Room number 02.6.056.1
Languages
German (Mother tongue)
English

Areas of expertise

Publications

Zurück
  • 2024
  • 2023
  • 2022
  • 2021
  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
Vor

A Comprehensive Analysis of Tn and STn Antigen Expression in Esophageal Adenocarcinoma
Mercanoglu B, Karstens K, Giannou A, Meiners J, Lücke J, Seeger P, Brackrock V, Güngör C, Izbicki J, Bockhorn M, Hackert T, Melling N, Wolters-Eisfeld G
CANCERS. 2024;16(2):.

Prognostic factors for intraoperative detection of necrotizing fasciitis in severe soft tissue infections
Abdalla T, Grotelüschen R, Abdalla A, Melling N, Izbicki J, Bachmann K
PLOS ONE. 2023;18(5):e0285048.

HLA-DP on Epithelial Cells Enables Tissue Damage by NKp44+ Natural Killer Cells in Ulcerative Colitis
Baumdick M, Niehrs A, Degenhardt F, Schwerk M, Hinrichs O, Jordan-Paiz A, Padoan B, Wegner L, Schloer S, Zecher B, Malsy J, Joshi V, Illig C, Schröder-Schwarz J, Möller K, Martin M, Yuki Y, Ozawa M, Sauter J, Schmidt A, Perez D, Giannou A, Carrington M, Davis R, Schumacher U, Sauter G, Huber S, Puelles V, Melling N, Franke A, Altfeld M, Bunders M
GASTROENTEROLOGY. 2023;165(4):946-962.e13.

Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22
Giannou A, Kempski J, Shiri A, Lücke J, Zhang T, Zhao L, Zazara D, Cortesi F, Riecken K, Amezcua Vesely M, Low J, Xu H, Kaffe E, Garcia-Perez L, Agalioti T, Yamada Y, Jungraithmayr W, Zigmond E, Karstens K, Steglich B, Wagner J, Konczalla L, Carambia A, Schulze K, von Felden J, May P, Briukhovetska D, Bedke T, Brockmann L, Starzonek S, Lange T, Koch C, Riethdorf S, Pelczar P, Böttcher M, Sabihi M, Huber F, Reeh M, Grass J, Wahib R, Seese H, Stüben B, Fard-Aghaie M, Duprée A, Scognamiglio P, Plitzko G, Meiners J, Soukou S, Wittek A, Manthey C, Maroulis I, Arck P, Perez D, Gao B, Zarogiannis S, Strowig T, Pasqualini R, Arap W, Gosálvez J, Kobold S, Prinz I, Guse A, Tachezy M, Ghadban T, Heumann A, Li J, Melling N, Mann O, Izbicki J, Pantel K, Schumacher U, Lohse A, Flavell R, Gagliani N, Huber S
IMMUNITY. 2023;56(1):125-142.e12.

IL-22BP controls the progression of liver metastasis in colorectal cancer
Giannou A, Kempski J, Zhang T, Lücke J, Shiri A, Zazara D, Belios I, Machicote A, Seeger P, Agalioti T, Tintelnot J, Sagebiel A, Tomczak M, Bauditz L, Bedke T, Kocheise L, Mercanoglu B, Fard-Aghaie M, Giorgakis E, Lykoudis P, Pikouli A, Grass J, Wahib R, Bardenhagen J, Brunswig B, Heumann A, Ghadban T, Duprée A, Tachezy M, Melling N, Arck P, Stringa P, Gentilini M, Gondolesi G, Nakano R, Thomson A, Perez D, Li J, Mann O, Izbicki J, Gagliani N, Maroulis I, Huber S
FRONT ONCOL. 2023;13:1170502.

Stoma-free survival after anastomotic leak following rectal cancer resection: worldwide cohort of 2470 patients
Greijdanus N, Wienholts K, Ubels S, Talboom K, Hannink G, Wolthuis A, de Lacy F, Lefevre J, Solomon M, Frasson M, Rotholtz N, Denost Q, Perez R, Konishi T, Panis Y, Rutegård M, Hompes R, Rosman C, van Workum F, Tanis P, de Wilt J
BRIT J SURG. 2023;110(12):1863-1876.

CXCR5+PD-1++ CD4+ T cells colonize infant intestines early in life and promote B cell maturation
Jordan-Paiz A, Martrus G, Steinert F, Kaufmann M, Sagebiel A, Schreurs R, Rechtien A, Baumdick M, Jung J, Möller K, Wegner L, Grüttner C, Richert L, Thünauer R, Schroeder-Schwarz J, van Goudoever J, Geijtenbeek T, Altfeld M, Pals S, Perez D, Klarenbeek P, Tomuschat C, Sauter G, Königs I, Schumacher U, Friese M, Melling N, Reinshagen K, Bunders M
CELL MOL IMMUNOL. 2023;20(2):201-213.

Muscle quality, not quantity, is associated with outcome after colorectal cancer surgery
Kemper M, Melling N, Krause L, Kühn K, Graß J, Izbicki J, Gerdes L, Adam G, Yamamura J, Molwitz I
EJSO-EUR J SURG ONC. 2023;49(12):107098.

Mindestmengen und Zertifizierungen der onkologischen Viszeralchirurgie in Deutschland – Fluch oder Segen?
Kemper M, Polonski A, Uzunoglu F, Melling N, Reeh M, Izbicki J, Graß J
Allgemein- und Viszeralchirurgie up2date. 2023;17(1):89-100.

Socioeconomic Deprivation Is Not Associated with Outcomes after Esophagectomy at a German High-Volume Center
Kemper M, Zagorski J, Wagner J, Graß J, Izbicki J, Melling N, Wolter S, Reeh M
CANCERS. 2023;15(10):.

Lymphatic Mapping in Colon Cancer Depending on Injection Time and Tracing Agent: A Systematic Review and Meta-Analysis of Prospective Designed Studies
Lucas K, Melling N, Giannou A, Reeh M, Mann O, Hackert T, Izbicki J, Perez D, Grass J
CANCERS. 2023;15(12):.

RAI3 expression is not associated with clinical outcomes of patients with non-small cell lung cancer
Melling N, Reeh M, Ghadban T, Tachezy M, Hajek A, Izbicki J, Grupp K
J CANCER RES CLIN. 2023;149(9):6549-6555.

Expanded ILC2s in human infant intestines promote tissue growth
Möller K, Wegner L, Malsy J, Baumdick M, Borggrewe M, Jordan-Paiz A, Jung J, Martrus G, Kretschmer P, Sagebiel A, Schreurs R, Hagen S, Burmester G, Clauditz T, Pals S, Boettcher M, Melling N, Sauter G, Tomuschat C, Königs I, Schumacher U, Altfeld M, Bernink J, Perez D, Reinshagen K, Bunders M
MUCOSAL IMMUNOL. 2023;16(4):408-421.

Robotic-assisted repair of incisional hernia-early experiences of a university robotic hernia program and comparison with open and minimally invasive sublay technique (eMILOS)
Plitzko G, Stüben B, Giannou A, Reeh M, Izbicki J, Melling N, Tachezy M
LANGENBECK ARCH SURG. 2023;408(1):.

Challenges in the interdisciplinary treatment of leakages after left-sided colorectal surgery: endoscopic negative pressure therapy, open-pore film drainage therapy and beyond
Scognamiglio P, Seeger A, Reeh M, Melling N, Karstens K, Rösch T, Izbicki J, Kantowski M, Tachezy M
INT J COLORECTAL DIS. 2023;38(1):138.

Intrathoracic vacuum therapy for the therapy of pleural empyema-a systematic review and analysis of the literature
Stüben B, Plitzko G, Reeh M, Melling N, Izbicki J, Bachmann K, Tachezy M
J THORAC DIS. 2023;15(2):780-790.

Minimally invasive intrathoracic negative-pressure therapy and flexible thoracoscopy (FlexVATS) for patients with pleural empyema
Stüben B, Plitzko G, Sauerbeck J, Busch P, Melling N, Reeh M, Izbicki J, Rösch T, Bachmann K, Tachezy M
SCI REP-UK. 2023;13(1):10869.

CD4+ T cell-derived IL-22 enhances liver metastasis by promoting angiogenesis
Zhang T, Wahib R, Zazara D, Lücke J, Shiri A, Kempski J, Zhao L, Agalioti T, Machicote A, Giannou O, Belios I, Jia R, Zhang S, Tintelnot J, Seese H, Grass J, Mercanoglu B, Stern L, Scognamiglio P, Fard-Aghaie M, Seeger P, Wakker J, Kemper M, Brunswig B, Duprée A, Lykoudis P, Pikouli A, Giorgakis E, Stringa P, Lausada N, Gentilini M, Gondolesi G, Bachmann K, Busch P, Grotelüschen R, Maroulis I, Arck P, Nakano R, Thomson A, Ghadban T, Tachezy M, Melling N, Achilles E, Puelles V, Nickel F, Hackert T, Mann O, Izbicki J, Li J, Gagliani N, Huber S, Giannou A
ONCOIMMUNOLOGY. 2023;12(1):2269634.

A Critical Role of the IL-22-IL-22 Binding Protein Axis in Hepatocellular Carcinoma
Giannou A, Lücke J, Kleinschmidt D, Shiri A, Steglich B, Nawrocki M, Zhang T, Zazara D, Kempski J, Zhao L, Giannou O, Agalioti T, Brockmann L, Bertram F, Sabihi M, Böttcher M, Ewald F, Schulze K, von Felden J, Machicote A, Maroulis I, Arck P, Graß J, Mercanoglu B, Reeh M, Wolter S, Tachezy M, Seese H, Theodorakopoulou M, Lykoudis P, Heumann A, Uzunoglu F, Ghadban T, Mann O, Izbicki J, Li J, Duprée A, Melling N, Gagliani N, Huber S
CANCERS. 2022;14(24):.

Risk stratification of cirrhotic patients undergoing esophagectomy for esophageal cancer: A single-centre experience
Grass J, Küsters N, Kemper M, Tintrup J, Piecha F, Izbicki J, Perez D, Melling N, Bockhorn M, Reeh M
PLOS ONE. 2022;17(3):e0265093.

Management of Esophageal Cancer-Associated Respiratory-Digestive Tract Fistulas
Grass J, Küsters N, von Döhren F, Melling N, Ghadban T, Rösch T, Simon M, Izbicki J, König A, Reeh M
CANCERS. 2022;14(5):.

Combined endoscopic-percutaneous treatment of upper gastrointestinal enterocutaneous fistula using vacuum therapy and resorbable plug insertion (Vac-Plug)
Kantowski M, Karstens K, Scognamiglio P, Melling N, Reeh M, Izbicki J, Rösch T, Tachezy M
SCI REP-UK. 2022;12(1):.

CD147 expression lacks prognostic relevance in esophageal cancer
Küsters N, Grupp K, Grass J, Bachmann K, Ghadban T, Uzunoglu F, Tachezy M, Perez D, Reeh M, Izbicki J, Melling N
J CANCER RES CLIN. 2022;148(4):837-844.

Management of intra-thoracic anastomotic leakages after esophagectomy: updated systematic review and meta-analysis of endoscopic vacuum therapy versus stenting
Scognamiglio P, Reeh M, Melling N, Kantowski M, Eichelmann A, Chon S, El-Sourani N, Schön G, Höller A, Izbicki J, Tachezy M
BMC SURG. 2022;22(1):.

Prognostic value of preoperative circulating tumor cells counts in patients with UICC stage I-IV colorectal cancer
Abdalla T, Meiners J, Riethdorf S, König A, Melling N, Gorges T, Karstens K, Izbicki J, Pantel K, Reeh M
PLOS ONE. 2021;16(6):e0252897.

Morphologic Factors Predict Pain Relief Following Pancreatic Head Resection in Chronic Pancreatitis Description of the Chronic Pancreatitis Pain Relief (CPPR) Score
Bachmann K, Melling N, Groteluschen R, Fleischauer A, Reeh M, Ghadban T, Bockhorn M, Izbicki J
ANN SURG. 2021;273(4):800-805.

Increased lysophosphatidylcholine acyltransferase 1 expression is unrelated to prognosis of esophageal cancer patients
Bellon E, Grupp K, Ghadban T, Tachezy M, Bachmann K, Izbicki J, Simon R, Sauter G, Hube-Magg C, Melling N
J CANCER RES CLIN. 2021;147(10):2879-2884.

Robotic rectal resection preserves anorectal function: Systematic review and meta-analysis
Grass J, Chen C, Melling N, Lingala B, Kemper M, Scognamiglio P, Persiani R, Tirelli F, Caricato M, Capolupo G, Izbicki J, Perez D
INT J MED ROBOT COMP. 2021;17(6):.

Robotic versus transanal total mesorectal excision in sexual, anorectal, and urinary function: a multicenter, prospective, observational study
Grass J, Persiani R, Tirelli F, Chen C, Caricato M, Pecorino A, Lang I, Kemper M, Izbicki J, Melling N, Perez D
INT J COLORECTAL DIS. 2021;36(12):2749-2761.

Acute Mesenteric Infarction: The Chameleon of Acute Abdomen Evaluating the Quality of the Diagnostic Parameters in Acute Mesenteric Ischemia
Grotelueschen R, Miller V, Heidelmann L, Melling N, Ghadban T, Grupp K, Reeh M, Welte M, Uzunoglu F, Izbicki J, Bachmann K
DIGEST SURG. 2021;38(2):149-157.

Serum midkine as non-invasive biomarker for detection and prognosis of non-small cell lung cancer
Stern L, Mueller E, Bellon E, Reeh M, Grotelüschen R, Guengoer C, Melling N, Goetz M, Perez D, Izbicki J, Rawnaq-Möllers T, Ghadban T
SCI REP-UK. 2021;11(1):.

Loss of cytoplasmic survivin expression is an independent predictor of poor prognosis in radically operated prostate cancer patients
Büscheck F, Sulimankhil M, Melling N, Höflmayer D, Hube-Magg C, Simon R, Göbel C, Hinsch A, Weidemann S, Izbicki J, Jacobsen F, Mandelkow T, Blessin N, Möller-Koop C, Lutz F, Viehweger F, Möller K, Sauter G, Lennartz M, Burandt E, Lebok P, Minner S, Bonk S, Huland H, Graefen M, Schlomm T, Fraune C
CANCER MED-US. 2020;9(4):1409-1418.

Antibiotic sensitivity in correlation to the origin of secondary peritonitis: a single center analysis
Grotelüschen R, Heidelmann L, Lütgehetmann M, Melling N, Reeh M, Ghadban T, Dupree A, Izbicki J, Bachmann K
SCI REP-UK. 2020;10(1):18588.

Loss of p16 and high Ki67 labeling index is associated with poor outcome in esophageal carcinoma
Jacobsen F, Kohsar J, Gebauer F, Kluth M, Hube-Magg C, Simon R, Bockhorn M, Hinsch A, Burandt E, Lübke A, Steurer S, Tachezy M, Sauter G, Izbicki J, Wilczak W, Melling N
ONCOTARGET. 2020;11(12):1007-1016.

Expression and serum levels of the neural cell adhesion molecule L1-like protein (CHL1) in gastrointestinal stroma tumors (GIST) and its prognostic power
Karstens K, Bellon E, Polonski A, Wolters-Eisfeld G, Melling N, Reeh M, Izbicki J, Tachezy M
ONCOTARGET. 2020;11(13):1131-1140.

First in Literature Intraneuronal Sacral Nerve Stimulation for Fecal Incontinence After Robotic-Assisted En-Bloc Sacrectomy with Transection of Nerve Roots
Melling N, Scognamiglio P, Teller S, Izbicki J, Dreimann M, Perez D
WORLD NEUROSURG. 2020;136:208-212.

Duodenum-preserving pancreatic head resection: A retrospective analysis of the Hamburg Modification
Bellon E, Roswora M, Melling N, Grotelueschen R, Grupp K, Reeh M, Ghadban T, Izbicki J, Bachmann K
SURGERY. 2019;165(5):938-945.

A nuclear shift of GSK3β protein is an independent prognostic factor in prostate cancer
Eichenauer T, Hussein M, Hube-Magg C, Kluth M, Büscheck F, Höflmayer D, Tsourlakis M, Steurer S, Clauditz T, Luebke A, Burandt E, Wilczak W, Hinsch A, Dum D, Beyer B, Steuber T, Huland H, Graefen M, Simon R, Sauter G, Melling N, Schlomm T, Minner S
ONCOTARGET. 2019;10(18):1729-1744.

High levels of RAI3 expression is linked to shortened survival in esophageal cancer patients
El Gammal A, Melling N, Reeh M, Gebauer F, Mann O, Perez D, Bockhorn M, Bachmann K, Izbicki J, Grupp K
EXP MOL PATHOL. 2019;107:51-56.

Protein expression of close homologue of L1 (CHL1) is a marker for overall survival in non-small cell lung cancer (NSCLC)
Hötzel J, Melling N, Müller J, Polonski A, Wolters-Eisfeld G, Izbicki J, Karstens K, Tachezy M
J CANCER RES CLIN. 2019;145(9):2285-2292.

Clotting factor activity in fresh frozen plasma after thawing with a new radio wave thawing device
Kuta P, Melling N, Zimmermann R, Achenbach S, Eckstein R, Strobel J
TRANSFUSION. 2019;59(5):1857-1861.

RAI3 is overexpressed in gastric adenocarcinoma but unrelated to prognosis
Melling N, Bachmann K, Bockhorn M, Mann O, Izbicki J, Grupp K
INT J CLIN EXP PATHO. 2019;12(2):606-612.

Prevalence and clinical significance of RBM3 immunostaining in non-small cell lung cancers
Melling N, Bachmann K, Hofmann B, El Gammal A, Reeh M, Mann O, Moebius C, Blessmann M, Izbicki J, Grupp K
J CANCER RES CLIN. 2019;145(4):873-879.

Robotic cholecystectomy: first experience with the new Senhance robotic system
Melling N, Barr J, Schmitz R, Polonski A, Miro J, Ghadban T, Wodack K, Izbicki J, Zani S, Perez D
J ROBOT SURG. 2019;13(3):495-500.

p53 overexpression is a prognosticator of poor outcome in esophageal cancer
Melling N, Norrenbrock S, Kluth M, Simon R, Hube-Magg C, Steurer S, Hinsch A, Burandt E, Jacobsen F, Wilczak W, Quaas A, Bockhorn M, Grupp K, Tachezy M, Izbicki J, Sauter G, Gebauer F
ONCOL LETT. 2019;17(4):3826-3834.

CHL1 and NrCAM are Primarily Expressed in Low Grade Pediatric Neuroblastoma
Wachowiak R, Mayer S, Suttkus A, Martynov I, Lacher M, Melling N, Izbicki J, Tachezy M
OPEN MED-WARSAW. 2019;14:920-927.

Reduced RBM3 expression is associated with aggressive tumor features in esophageal cancer but not significantly linked to patient outcome
Grupp K, Hofmann B, Kutup A, Bachmann K, Bogoevski D, Melling N, Uzunoglu F, El Gammal A, Koop C, Simon R, Steurer S, Krech T, Burdak-Rothkamm S, Jacobsen F, Sauter G, Izbicki J, Wilczak W
BMC CANCER. 2018;18(1):1106.

Expression of ICAM-1, E-cadherin, periostin and midkine in metastases of pancreatic ductal adenocarcinomas
Grupp K, Melling N, Bogoevska V, Reeh M, Uzunoglu F, El Gammal A, Nentwich M, Izbicki J, Bogoevski D
EXP MOL PATHOL. 2018;104(2):109-113.

FOXO1 overexpression and loss of pSerine256-FOXO1 expression predicts clinical outcome in esophageal adenocarcinomas
Grupp K, Uzunoglu F, Melling N, Hofmann B, El Gammal A, Grotelüschen R, Heumann A, Bellon E, Reeh M, Wolters-Eisfeld G, Ghabdan T, Nentwich M, Bachmann K, Bockhorn M, Bogoevski D, Izbicki J, Kutup A
SCI REP-UK. 2018;8(1):17370.

Robotic low anterior resection versus transanal total mesorectal excision in rectal cancer: A comparison of 115 cases
Perez D, Melling N, Biebl M, Reeh M, Baukloh J, Miro J, Polonski A, Izbicki J, Knoll B, Pratschke J, Aigner F
EJSO-EUR J SURG ONC. 2018;44(2):237-242.

Family with sequence similarity 13C (FAM13C) overexpression is an independent prognostic marker in prostate cancer
Burdelski C, Borcherding L, Kluth M, Hube-Magg C, Melling N, Simon R, Möller-Koop C, Weigand P, Minner S, Haese A, Michl H, Tsourlakis M, Jacobsen F, Hinsch A, Wittmer C, Lebok P, Steurer S, Izbicki J, Sauter G, Krech T, Büscheck F, Clauditz T, Schlomm T, Wilczak W
ONCOTARGET. 2017;8(19):31494-31508.

Protein S100A8/A9: A Potential New Biomarker for Pancreatic Diseases
El Gammal A, Sturm J, Pinnschmidt H, Hofmann B, Bellon E, Ghadban T, Melling N, Bachmann K, Izbicki J, Bockhorn M, Güngör C, Perez D
Int J Clin Endocrinol Metab. 2017;3(1):023-028.

Up-regulation of Biglycan is Associated with Poor Prognosis and PTEN Deletion in Patients with Prostate Cancer
Jacobsen F, Kraft J, Schroeder C, Hube-Magg C, Kluth M, Lang D, Simon R, Sauter G, Izbicki J, Clauditz T, Luebke A, Hinsch A, Wilczak W, Wittmer C, Büscheck F, Höflmayer D, Minner S, Tsourlakis M, Huland H, Graefen M, Budäus L, Thederan I, Salomon G, Schlomm T, Melling N
NEOPLASIA. 2017;19(9):707-715.

Increased ERCC1 expression is linked to chromosomal aberrations and adverse tumor biology in prostate cancer
Jacobsen F, Taskin B, Melling N, Sauer C, Wittmer C, Hube-Magg C, Kluth M, Simon R, Pehrke D, Beyer B, Steuber T, Thederan I, Sauter G, Schlomm T, Wilczak W, Möller K, Weidemann S, Burdak-Rothkamm S
BMC CANCER. 2017;17(1):504.

High-Level γ-Glutamyl-Hydrolase (GGH) Expression is Linked to Poor Prognosis in ERG Negative Prostate Cancer
Melling N, Rashed M, Schroeder C, Hube-Magg C, Kluth M, Lang D, Simon R, Möller-Koop C, Steurer S, Sauter G, Jacobsen F, Büscheck F, Wittmer C, Clauditz T, Krech T, Tsourlakis M, Minner S, Huland H, Graefen M, Budäus L, Thederan I, Salomon G, Schlomm T, Wilczak W
INT J MOL SCI. 2017;18(2):286.

The branched-chain amino acid transaminase 1 sustains growth of antiestrogen-resistant and ERα-negative breast cancer
Thewes V, Simon R, Hlevnjak M, Schlotter M, Schroeter P, Schmidt K, Wu Y, Anzeneder T, Wang W, Windisch P, Kirchgäßner M, Melling N, Kneisel N, Büttner R, Deuschle U, Sinn H, Schneeweiss A, Heck S, Kaulfuss S, Hess-Stumpp H, Okun J, Sauter G, Lykkesfeldt A, Zapatka M, Radlwimmer B, Lichter P, Tönjes M
ONCOGENE. 2017;36(29):4124-4134.

Glasgow Prognostic Score may be a prognostic index for overall and perioperative survival in gastric cancer without perioperative treatment
Melling N, Grüning A, Tachezy M, Nentwich M, Reeh M, Uzunoglu F, Vashist Y, Izbicki J, Bogoevski D
SURGERY. 2016;159(6):1548-56.

High Ki67 expression is an independent good prognostic marker in colorectal cancer
Melling N, Kowitz C, Simon R, Bokemeyer C, Terracciano L, Sauter G, Izbicki J, Marx A
J CLIN PATHOL. 2016;69(3):209-14.

Cytoplasmic accumulation of ELAVL1 is an independent predictor of biochemical recurrence associated with genomic instability in prostate cancer
Melling N, Taskin B, Hube-Magg C, Kluth M, Minner S, Koop C, Grob T, Graefen M, Heinzer H, Tsourlakis M, Izbicki J, Wittmer C, Huland H, Simon R, Wilczak W, Sauter G, Steurer S, Schlomm T, Krech T
PROSTATE. 2016;76(3):259-72.

Aquaporin 5 expression is frequent in prostate cancer and shows a dichotomous correlation with tumor phenotype and PSA recurrence
Pust A, Kylies D, Hube-Magg C, Kluth M, Minner S, Koop C, Grob T, Graefen M, Salomon G, Tsourlakis M, Izbicki J, Wittmer C, Huland H, Simon R, Wilczak W, Sauter G, Steurer S, Krech T, Schlomm T, Melling N
HUM PATHOL. 2016;48:102-10.

Loss of SOX9 Expression Is Associated with PSA Recurrence in ERG-Positive and PTEN Deleted Prostate Cancers
Burdelski C, Bujupi E, Tsourlakis M, Hube-Magg C, Kluth M, Melling N, Lebok P, Minner S, Koop C, Graefen M, Heinzer H, Wittmer C, Sauter G, Wilczak W, Simon R, Schlomm T, Steurer S, Krech T
PLOS ONE. 2015;10(6):e0128525.

The prognostic value of SUMO1/Sentrin specific peptidase 1 (SENP1) in prostate cancer is limited to ERG-fusion positive tumors lacking PTEN deletion
Burdelski C, Menan D, Tsourlakis M, Kluth M, Hube-Magg C, Melling N, Minner S, Koop C, Graefen M, Heinzer H, Wittmer C, Sauter G, Simon R, Schlomm T, Steurer S, Krech T
BMC CANCER. 2015;15:538.

HDAC1 overexpression independently predicts biochemical recurrence and is associated with rapid tumor cell proliferation and genomic instability in prostate cancer
Burdelski C, Ruge O, Melling N, Koop C, Simon R, Steurer S, Sauter G, Kluth M, Hube-Magg C, Minner S, Wittmer C, Wilczak W, Hinsch A, Lebok P, Izbicki J, Heinzer H, Graefen M, Huland H, Schlomm T, Krech T
EXP MOL PATHOL. 2015;98(3):419-426.

Overexpression of thymidylate synthase (TYMS) is associated with aggressive tumor features and early PSA recurrence in prostate cancer
Burdelski C, Strauss C, Tsourlakis M, Kluth M, Hube-Magg C, Melling N, Lebok P, Minner S, Koop C, Graefen M, Heinzer H, Wittmer C, Krech T, Sauter G, Wilczak W, Simon R, Schlomm T, Steurer S
ONCOTARGET. 2015.

High intratumoral FOXP3⁺ T regulatory cell (Tregs) density is an independent good prognosticator in nodal negative colorectal cancer
Hanke T, Melling N, Simon R, Sauter G, Bokemeyer C, Lebok P, Terracciano L, Izbicki J, Marx A
AM J CLIN PATHOL. 2015;8(7):8227-35.

Loss of H2Bub1 Expression is Linked to Poor Prognosis in Nodal Negative Colorectal Cancers
Melling N, Grimm N, Simon R, Stahl P, Bokemeyer C, Terracciano L, Sauter G, Izbicki J, Marx A
PATHOL ONCOL RES. 2015;22(1):95-102.

High-Level HOOK3 Expression Is an Independent Predictor of Poor Prognosis Associated with Genomic Instability in Prostate Cancer
Melling N, Harutyunyan L, Hube-Magg C, Kluth M, Simon R, Lebok P, Minner S, Tsourlakis M, Koop C, Graefen M, Adam M, Haese A, Wittmer C, Steurer S, Izbicki J, Sauter G, Wilczak W, Schlomm T, Krech T
PLOS ONE. 2015;10(7):e0134614.

Cdc7 overexpression is an independent prognostic marker and a potential therapeutic target in colorectal cancer
Melling N, Muth J, Simon R, Bokemeyer C, Terracciano L, Sauter G, Izbicki J, Marx A
DIAGN PATHOL. 2015;10:125.

Expression of phospho-mTOR kinase is abundant in colorectal cancer and associated with left-sided tumor localization
Melling N, Simon R, Izbicki J, Terracciano L, Bokemeyer C, Sauter G, Marx A
AM J CLIN PATHOL. 2015;8(6):7009-15.

Loss of RNA-binding motif protein 3 expression is associated with right-sided localization and poor prognosis in colorectal cancer
Melling N, Simon R, Mirlacher M, Izbicki J, Stahl P, Terracciano L, Bokemeyer C, Sauter G, Marx A
HISTOPATHOLOGY. 2015;68(2):191-8.

Overexpression of enhancer of zeste homolog 2 (EZH2) characterizes an aggressive subset of prostate cancers and predicts patient prognosis independently from pre- and postoperatively assessed clinicopathological parameters
Melling N, Thomsen E, Tsourlakis M, Kluth M, Hube-Magg C, Minner S, Koop C, Graefen M, Heinzer H, Wittmer C, Sauter G, Wilczak W, Huland H, Simon R, Schlomm T, Steurer S, Krech T
CARCINOGENESIS. 2015;36(11):1333-40.

Salvage Completion Pancreatectomies as Damage Control for Post-pancreatic Surgery Complications: A Single-Center Retrospective Analysis
Nentwich M, El Gammal A, Lemcke T, Ghadban T, Bellon E, Melling N, Bachmann K, Reeh M, Uzunoglu F, Izbicki J, Bockhorn M
WORLD J SURG. 2015;39(6):1550-6.

Zertifizierungen in der onkologischen Chirurgie: Bedeutung für die Wahl der Behandlungsstätte
Melling N, Drabik A, El Gammal A, Antonakis F, Darmann I, Izbicki J, Bockhorn M
CHIRURG. 2014;86(7):687-695.

Single versus double Roux-en-Y reconstruction techniques in pancreaticoduodenectomy: a comparative single-center study
Uzunoglu F, Reeh M, Wollstein R, Melling N, Perez D, Vashist Y, Bogoevski D, Izbicki J, Bockhorn M
WORLD J SURG. 2014;38(12):3228-3234.

Letzte Aktualisierung aus dem FIS: 19.04.2024 - 06:56 Uhr