Leon-Gordian Leonhardt
Dr. med.
Leon-Gordian Leonhardt
  • Research fellow
  • Assistant Physician
Working area

Location

Main Building O10 , 2nd Floor
Languages
German (Mother tongue)
English

Areas of expertise

Publications

2026

Symptom-related suicidal ideation in a tertiary spine center: Insights from a prospective outpatient cohort of 758 patients
Bay A, Mende K, Stangenberg M, Leonhardt L, Loose S, Mohme T, Fritsch G, Viezens L, Dreimann M, Eicker S, Mohme M
BRAIN SPINE. 2026;2025(104887):.

Enrichment of CD103 + CD4 + T cells in bone metastases compared to non-malignant controls.
Brauneck E, Kylies J, Assemissen A, Kruppa M, Kruppa N, Wahid Y, Brauneck F, Fiedler W, Viezens L, Wellbrock J, Leonhardt L
IMMUNOL LETT. 2026;279:107135.

Predicting survival of patients with spinal involvement in multiple myeloma using PATHFx 3.0 - a validation study of 100 patients in Germany
Kylies J, Brauneck E, Ballhause T, Weisel K, Schomacher M, Schroeder M, Obid P, Leonhardt L, Viezens L
WORLD J SURG ONCOL. 2026;24(1):.

Systemic bone loss measured by routine CT is associated with increased pain, postural decompensation, and survival in multiple myeloma
Kylies J, Weisel K, M Ballhause T, Schroeder M, Obid P, Schomacher M, Krueger L, Leonhardt L, Viezens L
EUR SPINE J. 2026.

Analysis of 4650 patients identifies previous spinal surgery, age, bmi, high blood loss, and open surgery as independent risk factors for deep wound infections
Leonhardt L, Alhamawandy S, Kylies J, Bay A, Krüger L, Dreimann M, Strahl A, Viezens L
BRAIN SPINE. 2026;2025(104888):.

Geriatric type II fractures of the dens axis: Biomechanical superiority of a new osteosynthesis plate compared to common anterior screw fixation
Leonhardt L, Münch M, Schroeder M, Dirks M, Kleinertz H, Kammal A, Ondruschka B, von Kroge S, Rolvien T, Frosch K, Bay A, Viezens L
GLOB SPINE J. 2026;16(1):98-106.

30-day postoperative mortality and the effects of hospital preparedness during the COVID-19 pandemic: a pooled analysis of prospective international cohort studies
NIHR Global Health Research Unit on Global Surgery , Böttcher A, Betz C, Bay A, Stangenberg M, Reiter A, Frosch K, Leonhardt L, Korthaus A, Priemel M, Klatte T
LANCET REG HEALTH-EU. 2026;62:101566.

2025

Konservative Therapie von Verletzungen der Halswirbelsäule
Arras C, Kylies J, Viezens L, Leonhardt L
UNFALLCHIRURGIE. 2025;128(2):96-102.

Overlooked burden of depression in spinal disease: A PHQ-9 analysis of 758 outpatients
Bay A, Mende K, Stangenberg M, Leonhardt L, Loose S, Mohme T, Fritsch G, Viezens L, Dreimann M, Eicker S, Mohme M
BRAIN SPINE. 2025;5(S3):104835.

Expression of the TIGIT axis and the CD39/CD73 purinergic pathway in bone metastasis-derived immune cells
Brauneck E, Leonhardt L, Assemissen A, Wahid Y, Kruppa M, Kruppa N, Krüger J, Menzel S, Koch-Nolte F, Kylies J, Weisel K, Bokemeyer C, Wellbrock J, Fiedler W, Viezens L, Brauneck F
CANCER IMMUNOL IMMUN. 2025;74(6):182.

Practice variations in indication, timing and outcome of Multiple Myeloma patients undergoing surgery for vertebral lesions - results from the European M2Spine study group
Hubertus V, Viezens L, Stangenberg M, Früh A, Meyer H, Liang R, Kramer A, Orban C, Kerschbaumer J, Kunze B, Telera S, Miller H, Entenmann C, von Bronewski E, Buhre C, Leonhardt L, Willenbacher W, Kvitsaridze I, Laue D, Pumberger M, Keller T, Acker G, Krönke J, Blau I, Keller U, Ringel F, Thomé C, Meyer B, Vajkoczy P, Dreimann M, Onken J
J NEURO-ONCOL. 2025;174(3):765-777.

Spinal metastases at the thoracolumbar junction - Influencing factors for surgical decision-making according to a multicentric registry
Hubertus V, Wagner A, Karbe A, Leonhardt L, Kunze B, Borchert S, Kilinc F, Mariño M, Nissimov N, Buhre C, Czabanka M, Dreimann M, Eicker S, Viezens L, Meyer H, Vajkoczy P, Meyer B, Onken J
BRAIN SPINE. 2025;5:104198.

Bone mass distribution of 892 distal tibiae and implications for the treatment of medial malleolar fractures
Kleinertz H, Mueller E, Leonhardt L, Thiesen D, Hofstätter B, Petersik A, Frosch K, Schlickewei C
FOOT ANKLE SURG. 2025;31(5):436-442.

Influence of foot orthoses on bone alignment parameters of the foot: a cadaveric weight-bearing CT study
Krüger L, Simon A, Goedecke E, Schlickewei C, Spethmann T, Leonhardt L, Hahn M, Beil F, Rolvien T
ARCH ORTHOP TRAUM SU. 2025;146(1):5.

Sarcopenia and fat loss from serial ct predict survival in multiple myeloma patients undergoing stem cell transplantation
Kylies J, Brauneck E, Priemel M, Kylies D, Weisel K, Leonhardt L, Viezens L
WORLD J SURG ONCOL. 2025;23(1):336.

Changes in sagittal spinopelvic alignment are associated with increased pain and impaired function in multiple myeloma patients
Kylies J, Dirks M, Brauneck E, Tessarzyk M, Dreimann M, Strahl A, Wolters W, Weisel K, Leonhardt L, Viezens L
EUR SPINE J. 2025;34(8):3513-3523.

Correction: Changes in sagittal spinopelvic alignment are associated with increased pain and impaired function in multiple myeloma patients
Kylies J, Dirks M, Brauneck E, Tessarzyk M, Dreimann M, Strahl A, Wolters W, Weisel K, Leonhardt L, Viezens L
EUR SPINE J. 2025;34(7):.

Bifocal surgery for malignant spinal lesions is associated with shorter postoperative survival and higher postoperative complication rates compared to monofocal surgery
Kylies J, Priemel M, Fritsch G, Brauneck E, Krüger L, Lenz M, Viezens L, Leonhardt L
SPINE J. 2025 [Epub ahead of print].

Superior biomechanical stability of pedicle screws compared to lateral mass screws: Recommendations for bicortical positioning and enhancing bone contact in geriatric C1 vertebrae
Leonhardt L, Rörup L, Kammal A, Hahn M, Dreimann M, Ondruschka B, von Brackel F, Rolvien T, Viezens L, von Kroge S
J ORTHOP SURG RES. 2025;20(1):63.

2024

A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts

LANCET DIGIT HEALTH. 2024;6(7):e507-e519.

Biopsies from patients with sacral insufficiency fracture are characterized by low bone matrix mineralization and high turnover
Delsmann M, Leonhardt L, Alimy A, Hoenig T, Beil F, Püschel K, von Brackel F, Amling M, Viezens L, Thiesen D, Rolvien T
JBMR PLUS. 2024;8(9):ziae094.

Safety of Intraoperative Cell Salvage in Two-Stage Revision of Septic Hip Arthroplasties
Krüger L, Strahl A, Goedecke E, Delsmann M, Leonhardt L, Beil F, Hubert J
ANTIBIOTICS-BASEL. 2024;13(9):.

A Combined Cyto- and Histopathological Diagnostic Approach Reduces Time to Diagnosis and Time to Therapy in First Manifestation of Metastatic Spinal Disease: A Cohort Study
Leonhardt L, Heuer A, Stangenberg M, Schroeder M, Schmidt G, Welker L, von Amsberg G, Strahl A, Krüger L, Dreimann M, Bokemeyer C, Viezens L, Asemissen A
CANCERS. 2024;16(9):.

2023

Cytology-histology correlation, time to diagnosis and time to therapy when cytology is performed in addition to biopsies in malignant spinal lesions of previously unknown malignant disease.
Asemissen A, Köpke L, Heuer A, Welker L, Stangenberg M, Lübke A, Schröder M, Dreimann M, Bokemeyer C, Viezens L, Krüger L
J CLIN ONCOL. 2023;41(16):.

Perioperatives Management nach traumatischer Querschnittslähmung: Komplikationen vermeiden
Heuer A, Koepke L, Viezens L, Schroeder M
UNFALLCHIRURGIE. 2023;126(10):749-755.

Analysis of Three-Dimensional Bone Microarchitecture of the Axis Exposes Pronounced Regional Heterogeneity Associated with Clinical Fracture Patterns
Koepke L, Kroge S, Heuer A, Kammal A, Ondruschka B, Rolvien T, Viezens L
CALCIFIED TISSUE INT. 2023;112(5):563-572.

The Use of Intraoperative Cell Salvage in Two-Stage Revision of Septic Hip Arthroplasties: A Double-Center Retrospective Study
Krüger L, Strahl A, Koepke L, Fink B, Beil F, Hubert J
ANTIBIOTICS-BASEL. 2023;12(6):982.

The PVCR (posterior vertebral column resection) as a safe procedure for the treatment of unstable metastases with extensive epidural tumor growth
Stangenberg M, Köpke L, Viezens L, Dreimann M, Heuer A
BRAIN SPINE. 2023;2(1):.

Conservative versus operative treatment of FFP II fractures in a geriatric cohort: a prospective randomized pilot trial
Thiesen D, Althoff G, Strahl A, Rolvien T, Frosch K, Koepke L, Arras C, Ballhause T, Dalos D, Hartel M
SCI REP-UK. 2023;13(1):.

2022

Impact of the COVID-19 pandemic on patients with paediatric cancer in low-income, middle-income and high-income countries: a multicentre, international, observational cohort study

BMJ OPEN. 2022;12(4):e054690.

SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study

ANAESTHESIA. 2022;77(1):28-39.

Twelve-month observational study of children with cancer in 41 countries during the COVID-19 pandemic

BMJ GLOB HEALTH. 2022;7(10):.

Densfraktur nach Hochrasanztrauma: Instabilität richtig einschätzen
Hemker K, Stangenberg M, Dreimann M, Köpke L, Heuer A, Viezens L
UNFALLCHIRURGIE. 2022;125(7):574-579.

Shortening time to diagnosis in malignant spinal lesions using a novel diagnostic fast track - a multidisciplinary approach
Heuer A, Köpke L, Stangenberg M, Strahl A, Dreimann M, Welker L, Bokemeyer C, Viezens L, Asemissen A
ONCOL RES TREAT. 2022;2022(45):254.

Novel diagnostic fast track using aspiration cytology in malignant spinal lesions – a multidisciplinary approach
Heuer A, Köpke L, Strahl A, Stangenberg M, Dreimann M, Welker L, Bokemeyer C, Asemissen A, Viezens L
Ger Med Sci. 2022;2022:.

Novel Hamburg spondylodiscitis assessment score (HSAS) for immediate mortality risk stratification on hospital admission
Heuer A, Köpke L, Viezens L, Strahl A, Stangenberg M, Dreimann M
BRAIN SPINE. 2022;2(1):.

The Hamburg Spondylodiscitis Assessment Score (HSAS) for Immediate Evaluation of Mortality Risk on Hospital Admission
Heuer A, Strahl A, Viezens L, Koepke L, Stangenberg M, Dreimann M
J CLIN MED. 2022;11(3):.

Surgical Site Cytology to Diagnose Spinal Lesions
Koepke L, Heuer A, Stangenberg M, Dreimann M, Welker L, Bokemeyer C, Strahl A, Asemissen A, Viezens L
DIAGNOSTICS. 2022;12(2):.

Outcome after Posterior Vertebral Column Resection in Patients with Severe Osteoporotic Fractures - A Retrospective Analysis from Two Centers
Koepke L, Weiser L, Stangenberg M, Dreimann M, Heuer A, Strahl A, Viezens L
MEDICINA-LITHUANIA. 2022;58(2):.

Design und biomechanische Untersuchung einer neuartigen anatomischen Osteosyntheseplatte für die Versorgung von Typ II Frakturen des Dens axis
Köpke L, Heuer A, Münch M, Stangenberg M, Frosch K, Dreimann M, Viezens L
Ger Med Sci. 2022;2022:.

17th German Spine Congress, Annual Meeting of the German Spine Society: Shortening the time to diagnosis and therapy in spinal lesions of unknown malignancy
Köpke L, Heuer A, Schmidt G, Strahl A, Stangenberg M, Dreimann M, Welker L, Bokemeyer C, Asemissen A, Viezens L
EUR SPINE J. 2022;31(11):3187-3187.

The limitations of fully threaded screws in isolated percutaneous transarticular screw fixation of C1/C2
Köpke L, Heuer A, Stangenberg M, Dreimann M, Beyerlein J, Schäfer C, Viezens L
SCI REP-UK. 2022;12(1):.

Spinal Stroke: Outcome Attenuation by Erythropoietin and Carbamylated Erythropoietin and Its Prediction by Sphingosine-1-Phosphate Serum Levels in Mice
Köpke L, Schwedhelm E, Ibing W, Oberhuber A, Daum G, Vcelar B, Schelzig H, Simon F
INT J MOL SCI. 2022;23(17):.

Neutrophil Extracellular Traps (NETs) im Gefäßsystem
Köpke L, Simon F, Heuer A
GEFASSCHIRURGIE. 2022;27(6):444-448.

Shortening the time to diagnosis in metastatic spine disease due to cancer of unknown primaries by a novel multidisciplinary fast track approach
Köpke L, Viezens L, Heuer A, Strahl A, Stangenberg M, Dreimann M, Asemissen A
BRAIN SPINE. 2022;2(1):.

17th German Spine Congress, Annual Meeting of the German Spine Society: The three-dimensional bone microstructure of the axis and clinical implications
Köpke L, von Kroge S, Heuer A, Kammal M, Ondruschka B, Rolvien T, Viezens L
EUR SPINE J. 2022;31(11):3240-3240.

Spontaneous spondylodiscitis and endocarditis interdisciplinary experience from a tertiary institutional case series and proposal of a treatment algorithm
Viezens L, Dreimann M, Strahl A, Heuer A, Koepke L, Bay B, Waldeyer C, Stangenberg M
NEUROSURG REV. 2022;45(2):1335-1342.

2021

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

BRIT J SURG. 2021;108(9):1056-1063.

Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study.

ANAESTHESIA. 2021;76(6):748-758.

Hamburg Spondylodiszitis-Score zur Einschätzung des Mortalitätsrisikos bei stationärer Aufnahme
Heuer A, Viezens L, Köpke L, Strahl A, Dreimann M, Stangenberg M
Ger Med Sci. 2021.

16th German Spine Congress Annual Meeting of the German Spine Society 9th to 11th December 2021 Muenster, Germany: Design and biomechanical investigation of a novel anatomic osteosynthesis plate for the treatment of type II dens axis fractures
Köpke L, Heuer A, Münch M, Stangenberg M, Dreimann M, Viezens L
EUR SPINE J. 2021;30(11):3362-3362.

16th German Spine Congress Annual Meeting of the German Spine Society 9th to 11th December 2021 Muenster, Germany: Aspiration cytology from malignant spinal lesions shortens time to diagnosis of previously unknown tumor disease
Köpke L, Heuer A, Stangenberg M, Dreimann M, Welker L, Bokemeyer C, Asemissen A, Viezens L
EUR SPINE J. 2021;30(11):3332-3333.

Posterior vertebral column resection as a safe procedure leading to solid bone fusion in metastatic epidural spinal cord compression
Viezens L, Dreimann M, Eicker S, Heuer A, Koepke L, Mohme M, Krätzig T, Stangenberg M
NEUROSURG FOCUS. 2021;50(5):E8.

16th German Spine Congress Annual Meeting of the German Spine Society 9th to 11th December 2021 Muenster, Germany: Posterior vertebral column resection (pVCR) leads to clinically good results and a reliable osseous fusion in cases of epidural tumor growth with concomitant instability
Viezens L, Dreimann M, Eicker S, Heuer A, Köpke L, Mohme M, Mohme T, Stangenberg M
EUR SPINE J. 2021;30(11):3333-3333.

Letzte Aktualisierung aus dem FIS: 24.02.2026 - 05:30 Uhr