Temporal change of DNA methylation subclasses between matched newly diagnosed and recurrent glioblastoma
Drexler R, Khatri R, Schüller U, Eckhardt A, Ryba A, Sauvigny T, Dührsen L, Mohme M, Ricklefs T, Bode H, Hausmann F, Huber T, Bonn S, Voß H, Neumann J, Silverbush D, Hovestadt V, Suvà M, Lamszus K, Gempt J, Westphal M, Heiland D, Hänzelmann S, Ricklefs F
ACTA NEUROPATHOL. 2024;147(1):21.

Defining benchmark outcomes for mesial temporal lobe epilepsy surgery: A global multicenter analysis of 1119 cases
Drexler R, Ricklefs F, Ben-Haim S, Rada A, Wörmann F, Cloppenborg T, Bien C, Simon M, Kalbhenn T, Colon A, Rijkers K, Schijns O, Borger V, Surges R, Vatter H, Rizzi M, de Curtis M, Didato G, Castelli N, Carpentier A, Mathon B, Yasuda C, Cendes F, Chandra P, Tripathi M, Clusmann H, Delev D, Guenot M, Haegelen C, Catenoix H, Lang J, Hamer H, Brandner S, Walther K, Hauptmann J, Jeffree R, Kegele J, Weinbrenner E, Naros G, Velz J, Krayenbühl N, Onken J, Schneider U, Holtkamp M, Rössler K, Spyrantis A, Strzelczyk A, Rosenow F, Stodieck S, Alonso-Vanegas M, Wellmer J, Wehner T, Dührsen L, Gempt J, Sauvigny T
EPILEPSIA. 2024 [Epub ahead of print].

Microsurgical Clipping of Unruptured Anterior Circulation Aneurysms-A Global Multicenter Investigation of Perioperative Outcomes
Sauvigny J, Drexler R, Pantel T, Ricklefs F, Catapano J, Wanebo J, Lawton M, Sanchin A, Hecht N, Vajkoczy P, Raygor K, Tonetti D, Abla A, El Naamani K, Tjoumakaris S, Jabbour P, Jankowitz B, Salem M, Burkhardt J, Wagner A, Wostrack M, Gempt J, Meyer B, Gaub M, Mascitelli J, Dodier P, Bavinzski G, Roessler K, Stroh N, Gmeiner M, Gruber A, Figueiredo E, Coelho A, Bervitskiy A, Anisimov E, Rzaev J, Krenzlin H, Keric N, Ringel F, Park D, Kim M, Marcati E, Cenzato M, Krause L, Westphal M, Dührsen L, Sauvigny T
NEUROSURGERY. 2024 [Epub ahead of print].

Brain Abscess Due to Streptococcus Anginosus After Professional Dental Cleaning
Brehm T, Flottmann F, Dührsen L
DTSCH ARZTEBL INT. 2023;120(1-2):13.

Multiple craniotomies in a single surgery - the resection of scattered brain metastases
Bschorer M, Ricklefs F, Sauvigny T, Westphal M, Dührsen L
NEUROSURG REV. 2023;46(1):70.

Targeted anticonvulsive treatment of IDH-wildtype glioblastoma based on DNA methylation subclasses
Drexler R, Göttsche J, Sauvigny T, Schüller U, Khatri R, Hausmann F, Hänzelmann S, Huber T, Bonn S, Heiland D, Delev D, Venkataramani V, Winkler F, Weller J, Zeyen T, Herrlinger U, Gempt J, Ricklefs F, Dührsen L
NEURO-ONCOLOGY. 2023;25(5):1006-1008.

Epigenetic neural glioblastoma enhances synaptic integration and predicts therapeutic vulnerability
Drexler R, Khatri R, Sauvigny T, Mohme M, Maire C, Ryba A, Zghaibeh Y, Dührsen L, Salviano-Silva A, Lamszus K, Westphal M, Gempt J, Wefers A, Neumann J, Bode H, Hausmann F, Huber T, Bonn S, Jütten K, Delev D, Weber K, Harter P, Onken J, Vajkoczy P, Capper D, Wiestler B, Weller M, Snijder B, Buck A, Weiss T, Keough M, Ni L, Monje M, Silverbush D, Hovestadt V, Suvà M, Krishna S, Hervey-Jumper S, Schüller U, Heiland D, Hänzelmann S, Ricklefs F
bioRxiv. 2023.

Association of the classification of intraoperative adverse events (ClassIntra) with complications and neurological outcome after neurosurgical procedures: a prospective cohort study
Drexler R, Ricklefs F, Pantel T, Göttsche J, Nitzschke R, Zöllner C, Westphal M, Dührsen L
ACTA NEUROCHIR. 2023;165(8):2015-2027.

Epigenetic profiling reveals a strong association between lack of 5-ALA fluorescence and EGFR amplification in IDH-wildtype glioblastoma
Drexler R, Sauvigny T, Schüller U, Eckhardt A, Maire C, Khatri R, Hausmann F, Hänzelmann S, Huber T, Bonn S, Bode H, Lamszus K, Westphal M, Dührsen L, Ricklefs F
NEURO-ONCOL PRACT. 2023;10(5):462-471.

DNA methylation subclasses predict the benefit from gross total tumor resection in IDH-wildtype glioblastoma patients
Drexler R, Schüller U, Eckhardt A, Filipski K, Hartung T, Harter P, Divé I, Forster M, Czabanka M, Jelgersma C, Onken J, Vajkoczy P, Capper D, Siewert C, Sauvigny T, Lamszus K, Westphal M, Dührsen L, Ricklefs F
NEURO-ONCOLOGY. 2023;25(2):315-325.

Histogram-Based Analysis of Low- and High-Grade Glioma and Its Surrounding Edema Using Arterial Spin Labeling Magnetic Resonance Imaging
Lindner T, Dührsen L, Kyselyova A, Entelmann W, Hau L, Fiehler J
APPL SCI-BASEL. 2023;13(19):.

Corticosteroid-Dependent Leukocytosis Masks the Predictive Potential of White Blood Cells for Delayed Cerebral Ischemia and Ventriculoperitoneal Shunt Dependency in Aneurysmatic Subarachnoid Hemorrhage
Piffko A, Ricklefs F, Schweingruber N, Sauvigny T, Mader M, Mohme M, Dührsen L, Westphal M, Regelsberger J, Schmidt N, Czorlich P
J CLIN MED. 2023;12(3):.

Machine learning based outcome prediction of microsurgically treated unruptured intracranial aneurysms
Stroh N, Stefanits H, Maletzky A, Kaltenleithner S, Thumfart S, Giretzlehner M, Drexler R, Ricklefs F, Dührsen L, Aspalter S, Rauch P, Gruber A, Gmeiner M
SCI REP-UK. 2023;13(1):22641.

Adult intracranial ependymoma-relevance of DNA methylation profiling for diagnosis, prognosis, and treatment
Träger M, Schweizer L, Pérez E, Schmid S, Hain E, Dittmayer C, Onken J, Fukuoka K, Ichimura K, Schüller U, Dührsen L, Müther M, Paulus W, Thomas C, Gutt-Will M, Schucht P, Maragkou T, Schittenhelm J, Eckert F, Niyazi M, Fleischmann D, Dorostkar M, Feyer P, May S, Moskopp D, Badakhshi H, Radke C, Walter J, Ehret F, Capper D, Kaul D
NEURO-ONCOLOGY. 2023;25(7):1286-1298.

Impact of the SARS-CoV-2 pandemic on the survival of patients with high-grade glioma and best practice recommendations
Vogel M, Wagner A, Gempt J, Krenzlin H, Zeyen T, Drexler R, Voss M, Nettekoven C, Abboud T, Mielke D, Rohde V, Timmer M, Goldbrunner R, Steinbach J, Dührsen L, Westphal M, Herrlinger U, Ringel F, Meyer B, Combs S
SCI REP-UK. 2023;13(1):2766.

The Comprehensive Complication Index (CCI) as a Measure of Postoperative Morbidity and Neurological Outcome after Elective Intracranial Surgery
Drexler R, Ricklefs F, Pantel T, Göttsche J, Westphal M, Dührsen L
J NEUROL SURG PART A. 2022 [Epub ahead of print].

Aneurysm Location Affects Clinical Course and Mortality in Patients With Subarachnoid Hemorrhage
Göttsche J, Piffko A, Pantel T, Westphal M, Dührsen L, Czorlich P, Sauvigny T
FRONT NEUROL. 2022;13:.

Experiences with a 3D4K digital exoscope system (ORBEYE) in a wide range of neurosurgical procedures
Göttsche J, Piffko A, Pantel T, Westphal M, Flitsch J, Ricklefs F, Regelsberger J, Dührsen L
J NEUROL SURG PART A. 2022;83(6):596-601.

Measurements of Functional Network Connectivity Using Resting State Arterial Spin Labeling During Neurosurgery
Lindner T, Ahmeti H, Helle M, Jansen O, Fiehler J, Dührsen L, Synowitz M, Kesari S, Ulmer S
WORLD NEUROSURG. 2022;157:152-158.

Diffusion tensor imaging changes in patients with glioma-associated seizures
Mader M, Deuter D, Sauvigny T, Borchert P, Faizy T, Bester M, Westphal M, Rosengarth K, Schmidt N, Sedlacik J, Dührsen L
J NEURO-ONCOL. 2022;160(2):311-320.

Single-Center Experience Using a 3D4K Digital Operating Scope System for Aneurysm Surgery
Pantel T, Drexler R, Göttsche J, Piffko A, Westphal M, Regelsberger J, Dührsen L
OPER NEUROSURG. 2022;22(6):433-439.

Clinical determinants impacting overall survival of patients with operable brain metastases from non-small cell lung cancer
Piffko A, Asey B, Dührsen L, Ristow I, Salamon J, Wikman H, Maire C, Lamszus K, Westphal M, Sauvigny T, Mohme M
FRONT ONCOL. 2022;12:.

DNA Methylation subclass Receptor Tyrosine Kinase II (RTK II) is predictive for seizure development in glioblastoma patients
Ricklefs F, Drexler R, Wollmann K, Eckhardt A, Heiland D, Sauvigny T, Maire C, Lamszus K, Westphal M, Schüller U, Dührsen L
NEURO-ONCOLOGY. 2022;24(11):1886-1897.

Genetic and epigenetic profiling identifies two distinct classes of spinal meningiomas
Ricklefs F, Fita K, Mohme M, Mawrin C, Rahmanzade R, Sahm F, Dührsen L, Göbel C, Lamszus K, Westphal M, Schüller U, Eicker S
ACTA NEUROPATHOL. 2022;144(5):1057-1059.

Diagnostic potential of extracellular vesicles in meningioma patients
Ricklefs F, Maire C, Wollmann K, Dührsen L, Fita K, Sahm F, Herold-Mende C, von Deimling A, Kolbe K, Holz M, Bergmann L, Fuh M, Schlüter H, Alawi M, Reimer R, Sven P, Glatzel M, Westphal M, Lamszus K
NEURO-ONCOLOGY. 2022;24(12):2078-2090.

Enhancing Safety in Epilepsy Surgery (EASINESS): Study Protocol for a Retrospective, Multicenter, Open Registry
Drexler R, Ben-Haim S, Bien C, Borger V, Cardinale F, Carpentier A, Cendes F, Chandra S, Clusmann H, Colon A, de Curtis M, Delev D, Didato G, Dührsen L, Farah J, Guenot M, Ghatan S, Haegelen C, Hamer H, Hauptmann J, Jeffree R, Kalbhenn T, Kegele J, Krayenbühl N, Lang J, Mathon B, Naros G, Onken J, Panov F, Raftopoulos C, Ricklefs F, Rijkers K, Rizzi M, Rössler K, Schijns O, Schneider U, Spyrantis A, Strzelczyk A, Stodieck S, Tripathi M, Vadera S, Alonso-Vanegas M, Vaz J, Wellmer J, Wehner T, Westphal M, Sauvigny T
FRONT NEUROL. 2021;12:.

Resective epilepsy surgery in patients aged 50years and older - a retrospective study regarding seizure outcome, memory performance, and psychopathology
Hebel J, Heerwig C, Möller H, Sauvigny T, Martens T, Dührsen L, Stodieck S, Brückner K, Lanz M
EPILEPSY BEHAV. 2021;118:.

Genome-wide methylation profiling of glioblastoma cell-derived extracellular vesicle DNA allows tumor classification
Maire C, Fuh M, Kaulich K, Fita K, Stevic I, Heiland D, Welsh J, Jones J, Görgens A, Ricklefs T, Dührsen L, Sauvigny T, Joosse S, Reifenberger G, Pantel K, Glatzel M, Miklosi A, Felce J, Caselli M, Pereno V, Reimer R, Schlüter H, Westphal M, Schüller U, Lamszus K, Ricklefs F
NEURO-ONCOLOGY. 2021;23(7):1087-1099.

Imaging-Based Outcome Prediction of Acute Intracerebral Hemorrhage
Nawabi J, Kniep H, Elsayed S, Friedrich C, Sporns P, Rusche T, Böhmer M, Morotti A, Schlunk F, Dührsen L, Broocks G, Schön G, Quandt F, Thomalla G, Fiehler J, Hanning U
TRANSL STROKE RES. 2021;12(6):958-967.

Decision-making in temporal lobe epilepsy surgery based on invasive stereo-electroencephalography (sEEG)
Dührsen L, Sauvigny T, Ricklefs F, Hamel W, Koeppen J, Hebel J, Lanz M, Martens T
NEUROSURG REV. 2020;43(5):1403-1408.

Initial pupil status is a strong predictor for in-hospital mortality after aneurysmal subarachnoid hemorrhage
Mader M, Piffko A, Dengler N, Ricklefs F, Dührsen L, Schmidt N, Regelsberger J, Westphal M, Wolf S, Czorlich P
SCI REP-UK. 2020;10(1):4764.

Glioma escape signature and clonal development under immune pressure
Maire C, Mohme M, Bockmayr M, Fita K, Riecken K, Börnigen D, Alawi M, Failla A, Kolbe K, Zapf S, Holz M, Neumann K, Dührsen L, Lange T, Fehse B, Westphal M, Lamszus K
J CLIN INVEST. 2020;130(10):5257-5271.

Local intracerebral immunomodulation using interleukin-expressing mesenchymal stem cells in glioblastoma
Mohme M, Maire C, Geumann U, Schliffke S, Dührsen L, Fita K, Akyüz N, Binder M, Westphal M, Guenther C, Lamszus K, Hermann F, Schmidt N
CLIN CANCER RES. 2020;26(11):2626-2639.

Inter- and Intrarater Agreement of Spot Sign and Noncontrast CT Markers for Early Intracerebral Hemorrhage Expansion
Nawabi J, Elsayed S, Kniep H, Sporns P, Schlunk F, McDonough R, Broocks G, Dührsen L, Schön G, Götz T, Fiehler J, Hanning U
J CLIN MED. 2020;9(4):.

Pik3ca mutations significantly enhance the growth of Shh medulloblastoma and lead to metastatic tumour growth in a novel mouse model
Niesen J, Ohli J, Sedlacik J, Dührsen L, Hellwig M, Spohn M, Holsten T, Schüller U
CANCER LETT. 2020;477:10-18.

FASN Is a Biomarker Enriched in Malignant Glioma-Derived Extracellular Vesicles
Ricklefs F, Maire C, Matschke J, Dührsen L, Sauvigny T, Holz M, Kolbe K, Peine S, Herold-Mende C, Carter B, Chiocca E, Lawler S, Westphal M, Lamszus K
INT J MOL SCI. 2020;21(6):.

Preclinical analysis of human mesenchymal stem cells: tumor tropism and therapeutic efficiency of local HSV-TK suicide gene therapy in glioblastoma
Dührsen L, Hartfuß S, Hirsch D, Geiger S, Maire C, Sedlacik J, Guenther C, Westphal M, Lamszus K, Hermann F, Schmidt N
ONCOTARGET. 2019;10(58):6049-6061.

Seizures as presenting symptom in patients with glioblastoma
Dührsen L, Sauvigny T, Ricklefs F, Mende K, Schaper M, Matschke J, Goebell E, Westphal M, Martens T
EPILEPSIA. 2019;60(1):149-154.

Relapse of a group 4 medulloblastoma after 18 years as proven by histology and DNA methylation profiling
Ricklefs F, Fritzsche F, Winkler B, Meissner B, Dührsen L, Westphal M, Rutkowski S, Martens T, Schüller U
CHILD NERV SYST. 2019;35(6):1029-1033.

Imaging flow cytometry facilitates multiparametric characterization of extracellular vesicles in malignant brain tumours
Ricklefs F, Maire C, Reimer R, Dührsen L, Kolbe K, Holz M, Schneider E, Rissiek A, Babayan A, Hille C, Pantel K, Krasemann S, Glatzel M, Heiland D, Flitsch J, Martens T, Schmidt N, Peine S, Breakefield X, Lawler S, Chiocca E, Fehse B, Giebel B, Görgens A, Westphal M, Lamszus K
J EXTRACELL VESICLES. 2019;8(1):1588555.

Rate and risk factors for a hyperactivity delirium in patients with aneurysmal subarachnoid haemorrhage
Sauvigny T, Mohme M, Grensemann J, Dührsen L, Regelsberger J, Kluge S, Schmidt N, Westphal M, Czorlich P
NEUROSURG REV. 2019;42(2):481-488.

Basilar impression as complication of Grisel's syndrome
Dührsen L, Abboud T, Viezens L, Eicker S, Dreimann M
CLIN CASE REP. 2018;6(1):185-188.

Impact of focal cortical dysplasia Type IIIa on seizure outcome following anterior mesial temporal lobe resection for the treatment of epilepsy
Dührsen L, Sauvigny T, House P, Stodieck S, Holst B, Matschke J, Schön G, Westphal M, Martens T
J NEUROSURG. 2018;128(6):1668-1673.

A 55-Year-Old Woman with Year-Long Headache and Dizziness
Dührsen L, Matschke J, Westphal M
BRAIN PATHOL. 2017;27(1):111-112.

A novel threshold criterion in transcranial motor evoked potentials during surgery for gliomas close to the motor pathway
Abboud T, Schaper M, Dührsen L, Schwarz C, Schmidt N, Westphal M, Martens T
J NEUROSURG. 2016;125(4):795-802.

Meninigiomas of the Craniocervical Junction - A Distinctive Subgroup of Meningiomas
Dührsen L, Emami P, Matschke J, Abboud T, Westphal M, Regelsberger J
PLOS ONE. 2016;11(4):e0153405.

Neuropsychological performance and seizure control after subsequent anteromesial temporal lobe resection following selective amygdalohippocampectomy
Sauvigny T, Brückner K, Dührsen L, Heese O, Westphal M, Stodieck S, Martens T
EPILEPSIA. 2016;57(11):1789-1797.

Serum levels of nimodipine in enteral and parenteral administration in patients with aneurysmal subarachnoid hemorrhage
Abboud T, Andresen-Streichert H, Koeppen J, Czorlich P, Dührsen L, Stenzig J, Westphal M, Regelsberger J
ACTA NEUROCHIR. 2015;157(5):763-767.

Minimally invasive approach for small ventrally located intradural lesions of the craniovertebral junction
Eicker S, Mende C, Dührsen L, Schmidt N
NEUROSURG FOCUS. 2015;38(4):E10.

Effects of repetitive exposure to pain and morphine treatment on the neonatal rat brain
Dührsen L, Simons S, Dzietko M, Genz K, Bendix I, Boos V, Sifringer M, Tibboel D, Felderhoff-Mueser U
NEONATOLOGY. 2013;103(1):35-43.

Letzte Aktualisierung aus dem FIS: 19.04.2024 - 06:57 Uhr