2025

Bauchpositionierung bei wachen kritisch kranken Patient:innen – eine Handlungsempfehlung

MED KLIN-INTENSIVMED. 2025 [Epub ahead of print].

Intravenous Ferric Carboxymaltose in Heart Failure With Iron Deficiency: The FAIR-HF2 DZHK05 Randomized Clinical Trial
Anker S, Friede T, Butler J, Talha K, Placzek M, Diek M, Nosko A, Stas A, Kluge S, Jarczak D, de Heer G, Rybczynski M, Bayés-Genís A, Böhm M, Coats A, Edelmann F, Filippatos G, Hasenfuß G, Haverkamp W, Lainscak M, Landmesser U, Macdougall I, Merkely B, Pieske B, Pinto F, Rassaf T, Visser-Rogers J, Rosano G, Volterrani M, von Haehling S, Anker M, Doehner W, Ince H, Koehler F, Savarese G, Khan M, Rauch-Kröhnert U, Gori T, Trenkwalder T, Akin I, Paitazoglou C, Kobielusz-Gembala I, Kuthi L, Frey N, Licka M, Kääb S, Laugwitz K, Ponikowski P, Karakas M
JAMA-J AM MED ASSOC. 2025;333(22):1965-1976.

Ferric carboxymaltose assessment of morbidity and mortality in patients with iron deficiency and chronic heart failure (FAIR-HF2-DZHK05) trial: Baseline characteristics and comparison to other relevant clinical trials
Anker S, Friede T, Butler J, Talha K, Placzek M, Diek M, Nosko A, Stas A, Kluge S, Jarczak D, de Heer G, Rybczynski M, Bayes-Genis A, Edelmann F, Filippatos G, Hasenfuß G, Haverkamp W, Lainscak M, Landmesser U, Macdougall I, Merkely B, Pieske B, Pinto F, Rassaf T, Volterrani M, von Haehling S, Anker M, Doehner W, Ince H, Koehler F, Savarese G, Rauch-Kröhnert U, Gori T, Trenkwalder T, Akin I, Paitazoglou C, Kobielusz-Gembala I, Zmuda W, Kuthi L, Frey N, Licka M, Kääb S, Laugwitz K, Ponikowski P, Karakas M
EUR J HEART FAIL. 2025;27(8):1436-1443.

In-hospital outcomes and 6-month follow-up results of patients supported with extracorporeal membrane oxygenation for COVID-19 from the second wave to the end of the pandemic (EuroECMO-COVID): a prospective, international, multicentre, observational study
De Piero M, Mariani S, van Bussel B, Jarczak D, Krenner N, de la Sota E, Silva P, Roemmer M, Kowalewski M, Carelli S, Broman L, Vuylsteke A, Fortuna P, Alessandri F, Martucci G, Patel B, Lotz G, Boeken U, Maier S, Filip B, Meyns B, Haenggi M, Puss S, Schellongowski P, Kirali K, Bolotin G, Barrett N, Riera J, Mueller T, Belohlavek J, Lorusso R
LANCET RESP MED. 2025;13(4):307-317.

Impact of bleeding and thrombosis on outcome of 945 COVID-19 VV-ECMO cases from a German registry
Herrmann J, Schade J, Meybohm P, Paschke N, Hübsch M, Notz Q, Groene J, Röder D, Kranke P, Merten M, Landoll M, Spieth P, Kluge S, Jarczak D, Roedl K, Sonntagbauer M, Putensen C, Schewe J, Ehrentraut S, Kreyer S, Wehrfritz A, Castellanos I, Bihlmaier K, Schmidt K, Brenner T, Herbstreit F, Espeter F, Wiefhoff J, Ellerkmann R, Oswald D, Ellger B, Lotz G, Raimann F, Wengenmayer T, Staudacher D, Zotzmann V, Moerer O, Kühn C, Kochanek M, Muellenbach R, Glaser P, Fichtner F, Bodenstein M, Findeisen M, Rembold V, Heim M, Schneider G, Lahmer T, Padberg J, Hullermann C, Lepper P, Becker A, Danziger G, Metz C, Rosenberger P, Mirakaj V, Bernard A, Braune S, Roth R, Grau A, Heuschmann P, Karagiannidis C, Lotz C
FRONT MED-LAUSANNE. 2025;12:1649217.

Targeting dipeptidyl peptidase 3 (DPP3) in extreme-critically ill patients with refractory shock: First-in-human report on the safety and efficacy of an anti-DPP3 antibody
Jarczak D, Nierhaus A, Mebazaa A, Herpain A, Pickkers P, Anar S, Kluge S
EUR J HEART FAIL. 2025;27(8):1483-1485.

Intravenous ferric carboxymaltose in heart failure with iron deficiency (FAIR-HF2 DZHK05 trial): Sex-specific outcomes
Karakas M, Friede T, Butler J, Talha K, Placzek M, Asendorf T, Diek M, Nosko A, Stas A, Kluge S, Jarczak D, DeHeer G, Rybczynski M, Bayes-Genis A, Böhm M, Coats A, Edelmann F, Filippatos G, Hasenfuß G, Haverkamp W, Lainscak M, Landmesser U, Macdougall I, Merkely B, Pieske B, Pinto F, Rassaf T, Visser-Rogers J, Rosano G, Volterrani M, von Haehling S, Anker M, Doehner W, Ince H, Koehler F, Savarese G, Khan M, Kröhnert U, Gori T, Trenkwalder T, Akin I, Paitazoglou C, Kobielusz-Gembala I, Kuthi L, Frey N, Licka M, Kääb S, Laugwitz K, Ponikowski P, Anker S
EUR J HEART FAIL. 2025 [Epub ahead of print].

High circulating dipeptidyl peptidase 3 predicts mortality and need for organ support in cardiogenic shock: An ancillary analysis of the ACCOST-HH trial
Picod A, Nordin H, Jarczak D, Zeller T, Oddos C, Santos K, Hartmann O, Herpain A, Mebazaa A, Kluge S, Azibani F, Karakas M
J CARD FAIL. 2025;31(1):29-36.

Die Videolaryngoskopie auf der Intensivstation – eine aktuelle Bewertung
Römer C, Jarczak D, Kluge S, Grensemann J
MED KLIN-INTENSIVMED. 2025 [Epub ahead of print].

2024

Septic shock due to Capnocytophaga canimorsus treated with IgM-enriched immunoglobulin as adjuvant therapy in an immunocompetent woman
Braunsteiner J, Siedler S, Jarczak D, Kluge S, Nierhaus A
Journal of Intensive Medicine. 2024;4(2):265-268.

Septic Hyperinflammation-Is There a Role for Extracorporeal Blood Purification Techniques?
Jarczak D, Kluge S, Nierhaus A
INT J MOL SCI. 2024;25(6):.

Impact of CytoSorb Hemoadsorption Therapy on Fluid Balance in Patients with Septic Shock
Kogelmann K, Hübner T, Drüner M, Jarczak D
J CLIN MED. 2024;13(1):.

Association of early changes in arterial carbon dioxide with acute brain injury in adult patients with extracorporeal membrane oxygenation: A ten-year retrospective study in a German tertiary care hospital
Yu Y, Lettow I, Roedl K, Jarczak D, Pinnschmidt H, Reichenspurner H, Bernhardt A, Söffker G, Schrage B, Haar M, Weber T, Frings D, Kluge S, Fischer M
J CRIT CARE. 2024;84:154880.

2023

Comparative analysis of characteristics and outcomes in hospitalized COVID-19 patients infected with different SARS-CoV-2 variants between January 2020 and April 2022 - A retrospective single-center cohort study
Brehm T, Heyer A, Woo M, Fischer M, van der Meirschen M, Wichmann D, Jarczak D, Roedl K, Schmiedel S, Addo M, Lütgehetmann M, Christner M, Huber S, Lohse A, Kluge S, Schulze Zur Wiesch J
J INFECT PUBLIC HEAL. 2023;16(11):1806-1812.

Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial
Higgins A, Berry L, Lorenzi E, Murthy S, McQuilten Z, Mouncey P, Al-Beidh F, Annane D, Arabi Y, Beane A, van Bentum-Puijk W, Bhimani Z, Bonten M, Bradbury C, Brunkhorst F, Burrell A, Buzgau A, Buxton M, Charles W, Cove M, Detry M, Estcourt L, Fagbodun E, Fitzgerald M, Girard T, Goligher E, Goossens H, Haniffa R, Hills T, Horvat C, Huang D, Ichihara N, Lamontagne F, Marshall J, McAuley D, McGlothlin A, McGuinness S, McVerry B, Neal M, Nichol A, Parke R, Parker J, Parry-Billings K, Peters S, Reyes L, Rowan K, Saito H, Santos M, Saunders C, Serpa-Neto A, Seymour C, Shankar-Hari M, Stronach L, Turgeon A, Turner A, van de Veerdonk F, Zarychanski R, Green C, Lewis R, Angus D, McArthur C, Berry S, Derde L, Gordon A, Webb S, Lawler P
JAMA-J AM MED ASSOC. 2023;329(1):39-51.

Effect of Hemadsorption Therapy in Critically Ill Patients with COVID-19 (CYTOCOV-19): A Prospective Randomized Controlled Pilot Trial
Jarczak D, Roedl K, Fischer M, Heer G, Burdelski C, Frings D, Sensen B, Boenisch O, Tariparast A, Kluge S, Nierhaus A
BLOOD PURIFICAT. 2023;52(2):183-192.

In-hospital and 6-month outcomes in patients with COVID-19 supported with extracorporeal membrane oxygenation (EuroECMO-COVID): a multicentre, prospective observational study
Lorusso R, De Piero M, Mariani S, Di Mauro M, Folliguet T, Taccone F, Camporota L, Swol J, Wiedemann D, Belliato M, Broman L, Vuylsteke A, Kassif Y, Scandroglio A, Fanelli V, Gaudard P, Ledot S, Barker J, Boeken U, Maier S, Kersten A, Meyns B, Pozzi M, Pedersen F, Schellongowski P, Kirali K, Barrett N, Riera J, Mueller T, Belohlavek J
LANCET RESP MED. 2023;11(2):151-162.

Impact of COVID-19 on Sedation Requirements during Veno-Venous Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome
Paparoupa M, Fischer M, Pinnschmidt H, Grensemann J, Roedl K, Kluge S, Jarczak D
J CLIN MED. 2023;12(10):.

Early acute kidney injury and transition to renal replacement therapy in critically ill patients with SARS-CoV-2 requiring veno-venous extracorporeal membrane oxygenation
Roedl K, De Rosa S, Fischer M, Braunsteiner J, Schmidt-Lauber C, Jarczak D, Huber T, Kluge S, Wichmann D
ANN INTENSIVE CARE. 2023;13(1):115.

CYP19A1 mediates severe SARS-CoV-2 disease outcome in males
Stanelle-Bertram S, Beck S, Mounogou N, Schaumburg B, Stoll F, Al Jawazneh A, Schmal Z, Bai T, Zickler M, Beythien G, Becker K, de la Roi M, Heinrich F, Schulz C, Sauter M, Krasemann S, Lange P, Heinemann A, van Riel D, Leijten L, Bauer L, van den Bosch T, Lopuhaä B, Busche T, Wibberg D, Schaudien D, Goldmann T, Lüttjohann A, Ruschinski J, Jania H, Müller Z, Pinho Dos Reis V, Krupp-Buzimkic V, Wolff M, Fallerini C, Baldassarri M, Furini S, Norwood K, Käufer C, Schützenmeister N, von Köckritz-Blickwede M, Schroeder M, Jarczak D, Nierhaus A, Welte T, Kluge S, McHardy A, Sommer F, Kalinowski J, Krauss-Etschmann S, Richter F, von der Thüsen J, Baumgärtner W, Klingel K, Ondruschka B, Renieri A, Gabriel G
CELL REP MED. 2023;4(9):101152.

Acute-on-chronic liver failure alters linezolid pharmacokinetics in critically ill patients with continuous hemodialysis: an observational study
Tikiso T, Fuhrmann V, König C, Jarczak D, Iwersen-Bergmann S, Kluge S, Wicha S, Grensemann J
ANN INTENSIVE CARE. 2023;13(1):83.

2022

Ciprofloxacin in Patients Undergoing Extracorporeal Membrane Oxygenation (ECMO): A Population Pharmacokinetic Study
Alihodzic D, Wicha S, Frey O, König C, Baehr M, Jarczak D, Kluge S, Langebrake C
PHARMACEUTICS. 2022;14(5):.

(1 → 3)-β-D-Glucan-guided antifungal therapy in adults with sepsis: the CandiSep randomized clinical trial
Bloos F, Held J, Kluge S, Simon P, Kogelmann K, de Heer G, Kuhn S, Jarczak D, Motsch J, Hempel G, Weiler N, Weyland A, Drüner M, Gründling M, Meybohm P, Richter D, Jaschinski U, Moerer O, Günther U, Schädler D, Weiss R, Putensen C, Castellanos I, Kurzai O, Schlattmann P, Cornely O, Bauer M, Thomas-Rüddel D
INTENS CARE MED. 2022;48(7):865-875.

Outcomes of critically ill coronavirus disease 2019 patients requiring kidney replacement therapy: A retrospective cohort study
Braunsteiner J, Kluge S, Schmidt-Lauber C, Boenisch O, de Heer G, Burdelski C, Frings D, Sensen B, Nierhaus A, Hoxha E, Huber T, Wichmann D, Kluge S, Fischer M, Roedl K
FRONT MED-LAUSANNE. 2022;9:.

Impaired Degradation of Neutrophil Extracellular Traps: A Possible Severity Factor of Elderly Male COVID-19 Patients
de Buhr N, Parplys A, Schroeder M, Henneck T, Schaumburg B, Stanelle-Bertram S, Jarczak D, Nierhaus A, Hiller J, Peine S, Kluge S, Klingel K, Gabriel G, von Köckritz-Blickwede M
J INNATE IMMUN. 2022;14(5):461-476.

Correction to: Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial
Hagel S, Bach F, Brenner T, Bracht H, Brinkmann A, Annecke T, Hohn A, Weigand M, Michels G, Kluge S, Nierhaus A, Jarczak D, König C, Weismann D, Frey O, Witzke D, Müller C, Bauer M, Kiehntopf M, Neugebauer S, Lehmann T, Roberts J, Pletz M
INTENS CARE MED. 2022;48(5):646-647.

Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial
Hagel S, Bach F, Brenner T, Bracht H, Brinkmann A, Annecke T, Hohn A, Weigand M, Michels G, Kluge S, Nierhaus A, Jarczak D, König C, Weismann D, Frey O, Witzke D, Müller C, Bauer M, Kiehntopf M, Neugebauer S, Lehmann T, Roberts J, Pletz M
INTENS CARE MED. 2022;48(3):311-321.

New Insights in the Occurrence of Venous Thromboembolism in Critically Ill Patients with COVID-19 - A Large Postmortem and Clinical Analysis
Heinrich F, Roedl K, Jarczak D, Goebels H, Heinemann A, Schäfer U, Ludwig F, Bachmann M, Bein B, Weber C, Sydow K, Bota M, Paschen H, Weerth A, Veit C, Detsch O, Brand P, Kluge S, Ondruschka B, Wichmann D
VIRUSES-BASEL. 2022;14(4):.

Key characteristics impacting survival of COVID-19 extracorporeal membrane oxygenation
Herrmann J, Lotz C, Karagiannidis C, Weber-Carstens S, Kluge S, Putensen C, Wehrfritz A, Schmidt K, Ellerkmann R, Oswald D, Lotz G, Zotzmann V, Moerer O, Kühn C, Kochanek M, Muellenbach R, Gaertner M, Fichtner F, Brettner F, Findeisen M, Heim M, Lahmer T, Rosenow F, Haake N, Lepper P, Rosenberger P, Braune S, Kohls M, Heuschmann P, Meybohm P
CRIT CARE. 2022;26(1):.

Remdesivir-induced emergence of SARS-CoV2 variants in patients with prolonged infection
Heyer A, Günther T, Robitaille A, Lütgehetmann M, Addo M, Jarczak D, Kluge S, Aepfelbacher M, Schulze Zur Wiesch J, Fischer N, Grundhoff A
CELL REP MED. 2022;3(9):.

Cytokine Storm - Definition, Causes, and Implications
Jarczak D, Nierhaus A
INT J MOL SCI. 2022;23(19):.

Single-dose of adrecizumab versus placebo in acute cardiogenic shock (ACCOST-HH): an investigator-initiated, randomised, double-blinded, placebo-controlled, multicentre trial
Karakas M, Akin I, Burdelski C, Clemmensen P, Grahn H, Jarczak D, Keßler M, Kirchhof P, Landmesser U, Lezius S, Lindner D, Mebazaa A, Nierhaus A, Ocak A, Rottbauer W, Sinning C, Skurk C, Söffker G, Westermann D, Zapf A, Zengin E, Zeller T, Kluge S
LANCET RESP MED. 2022;10(3):247-254.

Eine Erhebung zum Impfstatus von COVID-19-Patienten auf Normal- und Intensivstationen in Hamburg
Kluge S, Jarczak D, Eberhardt R, Herrlinger K, Janneck M, Borlich O, Weber C, Schley J, Emami P, Bergmann M, Addo M, Kerner T
DEUT MED WOCHENSCHR. 2022;147(8):492-494.

Reply to Supady et al. On the Use of Hemadsorption with CytoSorb in Patients with Septic Shock. Comment on "Kogelmann et al. First Evaluation of a New Dynamic Scoring System Intended to Support Prescription of Adjuvant CytoSorb Hemoadsorption Therapy in Patients with Septic Shock. J. Clin. Med. 2021, 10, 2939"
Kogelmann K, Hübner T, Schwameis F, Drüner M, Scheller M, Jarczak D
J CLIN MED. 2022;11(5):.

Comparison of the CytoSorb® 300 mL and Jafron HA380 hemoadsorption devices: an in vitro study
Nierhaus A, Morales J, Wendt D, Scheier J, Gutzler D, Jarczak D, Born F, Hagl C, Deliargyris E, Mehta Y
MINIM INVASIV THER. 2022;31(7):1058-1065.

Intravenous IgM-enriched immunoglobulins in critical COVID-19: a multicentre propensity-weighted cohort study
Rahmel T, Kraft F, Haberl H, Achtzehn U, Brandenburger T, Neb H, Jarczak D, Dietrich M, Magunia H, Zimmer F, Basten J, Landgraf C, Koch T, Zacharowski K, Weigand M, Rosenberger P, Ullrich R, Meybohm P, Nierhaus A, Kindgen-Milles D, Timmesfeld N, Adamzik M
CRIT CARE. 2022;26(1):.

Chronic Critical Illness in Patients with COVID-19: Characteristics and Outcome of Prolonged Intensive Care Therapy
Roedl K, Jarczak D, Boenisch O, de Heer G, Burdelski C, Frings D, Sensen B, Nierhaus A, Kluge S, Wichmann D
J CLIN MED. 2022;11(4):.

Replication of SARS-CoV-2 in adipose tissue determines organ and systemic lipid metabolism in hamsters and humans
Zickler M, Stanelle-Bertram S, Ehret S, Heinrich F, Lange P, Schaumburg B, Kouassi N, Beck S, Jaeckstein M, Mann O, Krasemann S, Schroeder M, Jarczak D, Nierhaus A, Kluge S, Peschka M, Schlüter H, Renné T, Pueschel K, Kloetgen A, Scheja L, Ondruschka B, Heeren J, Gabriel G
CELL METAB. 2022;34(1):1-2.

2021

Patient Characteristics and Clinical Course of COVID-19 Patients Treated at a German Tertiary Center during the First and Second Waves in the Year 2020
Brehm T, Heyer A, Roedl K, Jarczak D, Nierhaus A, Nentwich M, van der Meirschen M, Schultze A, Christner M, Fiedler W, Kröger N, Huber T, Klose H, Sterneck M, Jordan S, Kreuels B, Schmiedel S, Addo M, Huber S, Lohse A, Kluge S, Schulze Zur Wiesch J
J CLIN MED. 2021;10(11):.

Comparison of clinical characteristics and disease outcome of COVID-19 and seasonal influenza
Brehm T, van der Meirschen M, Hennigs A, Roedl K, Jarczak D, Wichmann D, Frings D, Nierhaus A, Oqueka T, Fiedler W, Christopeit M, Kraef C, Schultze A, Lütgehetmann M, Addo M, Schmiedel S, Kluge S, Schulze Zur Wiesch J
SCI REP-UK. 2021;11(1):.

Registry on extracorporeal multiple organ support with the advanced organ support (ADVOS) system: 2-year interim analysis
Fuhrmann V, Perez Ruiz de Garibay A, Faltlhauser A, Tyczynski B, Jarczak D, Lutz J, Weinmann-Menke J, Kribben A, Kluge S
MEDICINE. 2021;100(7):e24653.

Voriconazole Pharmacokinetics Are Not Altered in Critically Ill Patients with Acute-on-Chronic Liver Failure and Continuous Renal Replacement Therapy: An Observational Study
Grensemann J, Pfaffendorf C, Wicha S, Koenig C, Roedl K, Jarczak D, Iwersen-Bergmann S, Manthey C, Kluge S, Fuhrmann V
MICROORGANISMS. 2021;9(10):2087.

Sepsis-Pathophysiology and Therapeutic Concepts
Jarczak D, Kluge S, Nierhaus A
FRONT MED-LAUSANNE. 2021;8:628302.

First Evaluation of a New Dynamic Scoring System Intended to Support Prescription of Adjuvant CytoSorb Hemoadsorption Therapy in Patients with Septic Shock
Kogelmann K, Hübner T, Schwameis F, Drüner M, Scheller M, Jarczak D
J CLIN MED. 2021;10(13):.

Pharmacokinetics of meropenem during advanced organ support (ADVOS®) and continuous renal replacement therapy
König C, Kluge S, Fuhrmann V, Jarczak D
INT J ARTIF ORGANS. 2021;44(10):783-786.

Association of COVID-19 with Intracranial Hemorrhage during Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome: A 10-Year Retrospective Observational Study
Pantel T, Roedl K, Jarczak D, Yu Y, Frings D, Sensen B, Pinnschmidt H, Bernhardt A, Cheng B, Lettow I, Westphal M, Czorlich P, Kluge S, Fischer M
J CLIN MED. 2021;11(1):.

Viral Dynamics of SARS-CoV-2 in Critically Ill Allogeneic Hematopoietic Stem Cell Transplant Recipients and Immunocompetent Patients with COVID-19
Roedl K, Heidenreich S, Pfefferle S, Jarczak D, Urbanowicz T, Nörz D, Aepfelbacher M, Kröger N, Kluge S, Lütgehetmann M, Christopeit M, Wichmann D
AM J RESP CRIT CARE. 2021;203(2):242-245.

Severe liver dysfunction complicating course of COVID-19 in the critically ill: multifactorial cause or direct viral effect?
Roedl K, Jarczak D, Drolz A, Wichmann D, Boenisch O, de Heer G, Burdelski C, Frings D, Sensen B, Nierhaus A, Lütgehetmann M, Kluge S, Fuhrmann V
ANN INTENSIVE CARE. 2021;11(1):.

MR-proAdrenomedullin as a predictor of renal replacement therapy in a cohort of critically ill patients with COVID-19
Roedl K, Jarczak D, Fischer M, Haddad M, Boenisch O, de Heer G, Burdelski C, Frings D, Sensen B, Karakas M, Kluge S, Nierhaus A
BIOMARKERS. 2021;26(5):417-424.

Mechanical ventilation and mortality among 223 critically ill patients with coronavirus disease 2019: A multicentric study in Germany
Roedl K, Jarczak D, Thasler L, Bachmann M, Schulte F, Bein B, Weber C, Schäfer U, Veit C, Hauber H, Kopp S, Sydow K, de Weerth A, Bota M, Schreiber R, Detsch O, Rogmann J, Frings D, Sensen B, Burdelski C, Boenisch O, Nierhaus A, de Heer G, Kluge S
AUST CRIT CARE. 2021;34(2):167-175.

Clinical Characteristics, Complications and Outcomes of Patients with Severe Acute Respiratory Distress Syndrome Related to COVID-19 or Influenza Requiring Extracorporeal Membrane Oxygenation—A Retrospective Cohort Study
Roedl K, Kahn A, Jarczak D, Fischer M, Boenisch O, Heer G, Burdelski C, Frings D, Sensen B, Nierhaus A, Braune S, Yildirim Y, Bernhardt A, Reichenspurner H, Kluge S, Wichmann D
J CLIN MED. 2021;10(22):.

Effects of COVID-19 on in-hospital cardiac arrest: incidence, causes, and outcome - a retrospective cohort study
Roedl K, Söffker G, Fischer D, Müller J, Westermann D, Issleib M, Kluge S, Jarczak D
SCAND J TRAUMA RESUS. 2021;29(1):30.

Characteristics and Risk Factors for Intensive Care Unit Cardiac Arrest in Critically Ill Patients with COVID-19—A Retrospective Study
Roedl K, Söffker G, Wichmann D, Boenisch O, de Heer G, Burdelski C, Frings D, Sensen B, Nierhaus A, Westermann D, Kluge S, Jarczak D
J CLIN MED. 2021;10(10):.

High estradiol and low testosterone levels are associated with critical illness in male but not in female COVID-19 patients: a retrospective cohort study
Schroeder M, Schaumburg B, Mueller Z, Parplys A, Jarczak D, Roedl K, Nierhaus A, Heer G, Grensemann J, Schneider B, Stoll F, Bai T, Jacobsen H, Zickler M, Stanelle-Bertram S, Klaetschke K, Renné T, Meinhardt A, Aberle J, Hiller J, Peine S, Kreienbrock L, Klingel K, Kluge S, Gabriel G
EMERG MICROBES INFEC. 2021;10(1):1807-1818.

Multi-dimensional and longitudinal systems profiling reveals predictive pattern of severe COVID-19
Woo M, Haag F, Nierhaus A, Jarczak D, Roedl K, Mayer C, Brehm T, van der Meirschen M, Hennigs A, Christopeit M, Fiedler W, Karagiannis P, Burdelski C, Schultze A, Huber S, Addo M, Schmiedel S, Friese M, Kluge S, Schulze Zur Wiesch J
ISCIENCE. 2021;24(7):102752.

Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients
Zhao Y, Kilian C, Turner J, Bosurgi L, Roedl K, Bartsch P, Gnirck A, Cortesi F, Schultheiß C, Hellmig M, Enk L, Hausmann F, Borchers A, Wong M, Paust H, Siracusa F, Scheibel N, Herrmann M, Rosati E, Bacher P, Kylies D, Jarczak D, Lütgehetmann M, Pfefferle S, Steurer S, Zur Wiesch J, Puelles V, Sperhake J, Addo M, Lohse A, Binder M, Huber S, Huber T, Kluge S, Bonn S, Panzer U, Gagliani N, Krebs C
SCI IMMUNOL. 2021;6(56):.

2020

Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial
Angus D, Derde L, Al-Beidh F, Annane D, Arabi Y, Beane A, van Bentum-Puijk W, Berry L, Bhimani Z, Bonten M, Bradbury C, Brunkhorst F, Buxton M, Buzgau A, Cheng A, de Jong M, Detry M, Estcourt L, Fitzgerald M, Goossens H, Green C, Haniffa R, Higgins A, Horvat C, Hullegie S, Kruger P, Lamontagne F, Lawler P, Linstrum K, Litton E, Lorenzi E, Marshall J, McAuley D, McGlothin A, McGuinness S, McVerry B, Montgomery S, Mouncey P, Murthy S, Nichol A, Parke R, Parker J, Rowan K, Sanil A, Santos M, Saunders C, Seymour C, Turner A, van de Veerdonk F, Venkatesh B, Zarychanski R, Berry S, Lewis R, McArthur C, Webb S, Gordon A
JAMA-J AM MED ASSOC. 2020;324(13):1317-1329.

Advanced organ support (ADVOS) in the critically ill: first clinical experience in patients with multiple organ failure
Fuhrmann V, Weber T, Roedl K, Motaabbed J, Tariparast A, Jarczak D, de Garibay A, Kluwe J, Boenisch O, Herkner H, Kellum J, Kluge S
ANN INTENSIVE CARE. 2020;10(1):96.

Challenges in treatment of patients with acute leukemia and COVID-19: a series of 12 patients
Ghandili S, Pfefferle S, Roedl K, Sonnemann P, Karagiannis P, Boenisch O, Kluge S, Schmiedel S, Ittrich H, Rohde H, Lütgehetmann M, Weisel K, Bokemeyer C, Wichmann D, Fiedler W, Jarczak D, Modemann F
BLOOD ADV. 2020;4(23):5936-5941.

Acute-on-chronic liver failure alters meropenem pharmacokinetics in critically ill patients with continuous hemodialysis: an observational study
Grensemann J, Busse D, König C, Roedl K, Jäger W, Jarczak D, Iwersen-Bergmann S, Manthey C, Kluge S, Kloft C, Fuhrmann V
ANN INTENSIVE CARE. 2020;10(1):48.

Use of Intravenous Immunoglobulins in Sepsis Therapy - A Clinical View
Jarczak D, Kluge S, Nierhaus A
INT J MOL SCI. 2020;21(15):.

Targeting Endothelial Dysfunction in Eight Extreme-Critically Ill Patients with COVID-19 Using the Anti-Adrenomedullin Antibody Adrecizumab (HAM8101)
Karakas M, Jarczak D, Becker M, Roedl K, Addo M, Hein F, Bergmann A, Zimmermann J, Simon T, Marx G, Lütgehetmann M, Nierhaus A, Kluge S
BIOMOLECULES. 2020;10(8):.

Use of hemoadsorption in sepsis-associated ECMO-dependent severe ARDS: A case series
Kogelmann K, Scheller M, Drüner M, Jarczak D
J INTENSIVE CARE SOC. 2020;21(2):183-190.

Kontroversen bei COVID-19
Nentwich M, Nierhaus A, Jarczak D, Kluge S
Intensiv News. 2020;24(3):1-5.

Epidemiology of intensive care unit cardiac arrest: characteristics, comorbidities, and post-cardiac arrest organ failure - a prospective observational study
Roedl K, Jarczak D, Blohm R, Winterland S, Müller J, Fuhrmann V, Westermann D, Söffker G, Kluge S
RESUSCITATION. 2020;156:92-98.

Effect of Regional Citrate Anticoagulation vs Systemic Heparin Anticoagulation During Continuous Kidney Replacement Therapy on Dialysis Filter Life Span and Mortality Among Critically Ill Patients With Acute Kidney Injury: A Randomized Clinical Trial
Zarbock A, Küllmar M, Kindgen-Milles D, Wempe C, Gerss J, Brandenburger T, Dimski T, Tyczynski B, Jahn M, Mülling N, Mehrländer M, Rosenberger P, Marx G, Simon T, Jaschinski U, Deetjen P, Putensen C, Schewe J, Kluge S, Jarczak D, Slowinski T, Bodenstein M, Meybohm P, Wirtz S, Moerer O, Kortgen A, Simon P, Bagshaw S, Kellum J, Meersch M
JAMA-J AM MED ASSOC. 2020;324(16):1629-1639.

2019

Successful therapy of massive risperidone-induced rhabdomyolysis using different dialysis and adsorber devices: A case report
Jarczak D, Kluge S, Fuhrmann V
ARTIF ORGANS. 2019;43(11):1113-1115.

Advances in Sepsis Treatment
Jarczak D, Nierhaus A
2019. Endotoxin Detection and Control in Pharma, Limulus, and Mammalian Systems. Williams K (eds.). 1. ed. Springer Nature Switzerland, 837-854.

2018

Comparing fiberoptic bronchoscopy and a tracheal tube-mounted camera-guided percutaneous dilatational tracheostomy: authors reply
Grensemann J, Eichler L, Kähler S, Jarczak D, Simon M, Pinnschmidt H, Kluge S
CRIT CARE. 2018;22(1):84.

Endotracheal tube-mounted camera-assisted intubation versus conventional intubation in intensive care: a prospective, randomised trial (VivalTN)
Grensemann J, Eichler L, Wang N, Jarczak D, Simon M, Kluge S
CRIT CARE. 2018;22(1):235.

Laktatazidose – Update 2018
Kluge S, de Heer G, Jarczak D, Nierhaus A, Fuhrmann V
DEUT MED WOCHENSCHR. 2018;143(15):1082-1085.

Long-term neurological outcomes in patients aged over 90 years who are admitted to the intensive care unit following cardiac arrest
Roedl K, Jarczak D, Becker S, Fuhrmann V, Kluge S, Müller J
RESUSCITATION. 2018;132(11):6-12.

2017

Extrakorporale Verfahren zur Lungenunterstützung
Braune S, Sieweke A, Jarczak D, Kluge S
MED KLIN-INTENSIVMED. 2017;112(5):426-463.

Feasibility of an endotracheal tube-mounted camera for percutaneous dilatational tracheostomy
Grensemann J, Eichler L, Hopf S, Jarczak D, Simon M, Kluge S
ACTA ANAESTH SCAND. 2017;61(6):660-667.

Bronchoscopy versus an endotracheal tube mounted camera for the peri-interventional visualization of percutaneous dilatational tracheostomy - a prospective, randomized trial (VivaPDT)
Grensemann J, Eichler L, Kähler S, Jarczak D, Simon M, Pinnschmidt H, Kluge S
CRIT CARE. 2017;21(1):330.

Extrakorporale Therapien bei Lebererkrankungen
Jarczak D, Braun G, Fuhrmann V
MED KLIN-INTENSIVMED. 2017;112(5):444-453.

NIV bei ARDS: LUNG SAFEty first
Kluge S, Jarczak D, Braune S
Intensiv News. 2017;21(2):.

Hemoadsorption by CytoSorb in septic patients: a case series
Kogelmann K, Jarczak D, Scheller M, Drüner M
CRIT CARE. 2017;21(1):74.

Organinteraktion Leber und Niere
Roedl K, Jarczak D, Fuhrmann V
DEUT MED WOCHENSCHR. 2017;142(18):1365-1372.

Outcome of in- and out-of-hospital cardiac arrest survivors with liver cirrhosis
Roedl K, Wallmüller C, Drolz A, Horvatits T, Rutter K, Spiel A, Ortbauer J, Stratil P, Hubner P, Weiser C, Motaabbed J, Jarczak D, Herkner H, Sterz F, Fuhrmann V
ANN INTENSIVE CARE. 2017;7(1):103.

2007

Inhibition of HCV subgenomic replicons by siRNAs derived from plasmids with opposing U6 and H1 promoters
Korf M, Meyer A, Jarczak D, Beger C, Manns M, Krüger M
J VIRAL HEPATITIS. 2007;14(2):122-32.

2005

Hairpin ribozymes in combination with siRNAs against highly conserved hepatitis C virus sequence inhibit RNA replication and protein translation from hepatitis C virus subgenomic replicons
Jarczak D, Korf M, Beger C, Manns M, Krüger M
FEBS J. 2005;272(22):5910-22.

Inhibition of hepatitis C virus translation and subgenomic replication by siRNAs directed against highly conserved HCV sequence and cellular HCV cofactors
Korf M, Jarczak D, Beger C, Manns M, Krüger M
J HEPATOL. 2005;43(2):225-34.

Letzte Aktualisierung aus dem FIS: 06.12.2025 - 05:42 Uhr