DiagnostySize for sample size calculation in Diagnostic Test Accuracy (DTA) studies

We developed the Shiny App DiagnostySize for sample size calculation in diagnostic test accuracy studies.

The following article provides detailed information about the Shiny App:

Wiesner J, Stark M, Frömke C, Zapf A. Shiny App for sample size calculation in diagnostic trials - DiagnostySize. Journal of Statistical Software (under review).

DiagnostySize is available on GitHub: https://github.com/JanaW09/DiagnostySize_App

and browser-based (no additional software required) via Posit Cloud:
https://019fb40c-7274-3149-1b88-9ed2294342bd.share.connect.posit.cloud

The methods for sample size calculation are given in the articles:

• Stark M, Zapf A (2020). “Sample size calculation and re-estimation based on the prevalence in a single-arm confirmatory diagnostic accuracy study.” Statistical Methods in Medical Research, 29(10), 2958–2971. doi:10.1177/0962280220913588.

• Stark M, Hesse M, Brannath W, Zapf A (2022). “Blinded sample size re-estimation in a comparative diagnostic accuracy study.” BMC Medical Research Methodology, 22(1), 115. doi:10.1186/s12874-022-01564-2.