Gunhild von Amsberg
Prof. Dr. med.
Gunhild von Amsberg
  • Senior physician
  • Medical Specialist in Internal Medicine and Hematology and Oncology
  • Palliative Medicine
Working area


O24 , Semi Basement , Room number 02
German (Mother tongue)

Areas of expertise



  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011
  • 2010
  • 2008

New Trisulfated Steroids from the Vietnamese Marine Sponge Halichondria vansoesti and Their PSA Expression and Glucose Uptake Inhibitory Activities
Tabakmakher K, Makarieva T, Denisenko V, Popov R, Dmitrenok P, Dyshlovoy S, Grebnev B, Bokemeyer C, von Amsberg G, Cuong N
MAR DRUGS. 2019;17(8):.

Auroglaucin-related neuroprotective compounds from Vietnamese marine sediment-derived fungus Aspergillus niveoglaucus
Yurchenko A, Smetanina O, Ivanets E, Phan T, Ngo N, Zhuravleva O, Rasin A, Dyshlovoy S, Menchinskaya E, Pislyagin E, von Amsberg G, Afiyatullov S, Yurchenko E
NAT PROD RES. 2019;1-6.

Prenylated indole alkaloids from co-culture of marine-derived fungi Aspergillus sulphureus and Isaria felina
Afiyatullov S, Zhuravleva O, Antonov A, Berdyshev D, Pivkin M, Denisenko V, Popov R, Gerasimenko A, von Amsberg G, Dyshlovoy S, Leshchenko E, Yurchenko A
J ANTIBIOT. 2018;71(10):846-853.

Synthesis and anticancer activity of the derivatives of marine compound rhizochalin in castration resistant prostate cancer
Dyshlovoy S, Otte K, Tabakmakher K, Hauschild J, Makarieva T, Shubina L, Fedorov S, Bokemeyer C, Stonik V, von Amsberg G
ONCOTARGET. 2018;9(24):16962-16973.

In Situ Detection and Quantification of AR-V7, AR-FL, PSA, and KRAS Point Mutations in Circulating Tumor Cells
El-Heliebi A, Hille C, Laxman N, Svedlund J, Haudum C, Ercan E, Kroneis T, Chen S, Smolle M, Rossmann C, Krzywkowski T, Ahlford A, Darai E, von Amsberg G, Alsdorf W, König F, Löhr M, de Kruijff I, Riethdorf S, Gorges T, Pantel K, Bauernhofer T, Nilsson M, Sedlmayr P
CLIN CHEM. 2018;64(3):536-546.

Cost-effectiveness analyses and cost analyses in castration-resistant prostate cancer: A systematic review
Grochtdreis T, König H, Dobruschkin A, von Amsberg G, Dams J
PLOS ONE. 2018;13(12):e0208063.

Asperindoles A⁻D and a -Terphenyl Derivative from the Ascidian-Derived Fungus sp. KMM 4676
Ivanets E, Yurchenko A, Smetanina O, Rasin A, Zhuravleva O, Pivkin M, Popov R, von Amsberg G, Afiyatullov S, Dyshlovoy S
MAR DRUGS. 2018;16(7):232.

Treatment of Metastatic Spindle Epithelial Tumor with Thymus-Like Differentiation (SETTLE) - Long-Term Disease Control by Multimodal Therapy
Quidde J, Alsdorf W, von Amsberg G, Wilczak W, Bokemeyer C
ONCOL RES TREAT. 2018;41(1-2):58-60.

Zosteropenillines: Polyketides from the Marine-Derived Fungus Penicillium thomii
Afiyatullov S, Leshchenko E, Berdyshev D, Sobolevskaya M, Antonov A, Denisenko V, Popov R, Pivkin M, Udovenko A, Pislyagin E, von Amsberg G, Dyshlovoy S, Kerr R
MAR DRUGS. 2017;15(2):46.

Axl Blockade by BGB324 Inhibits BCR-ABL Tyrosine Kinase Inhibitor-Sensitive and -Resistant Chronic Myeloid Leukemia
Ben Batalla I, Erdmann R, Jørgensen H, Mitchell R, Ernst T, von Amsberg G, Schafhausen P, Velthaus J, Rankin S, Clark R, Koschmieder S, Schultze A, Mitra S, Vandenberghe P, Brümmendorf T, Carmeliet P, Hochhaus A, Pantel K, Bokemeyer C, Helgason G, Holyoake T, Loges S
CLIN CANCER RES. 2017;23(9):2289-2300.

The marine triterpene glycoside frondoside A induces p53-independent apoptosis and inhibits autophagy in urothelial carcinoma cells
Dyshlovoy S, Madanchi R, Hauschild J, Otte K, Alsdorf W, Schumacher U, Kalinin V, Silchenko A, Avilov S, Honecker F, Stonik V, Bokemeyer C, von Amsberg G
BMC CANCER. 2017;17(1):93.

Proteomic-based investigations on the mode of action of the marine anticancer compound rhizochalinin
Dyshlovoy S, Otte K, Venz S, Hauschild J, Junker H, Makarieva T, Balabanov S, Alsdorf W, Madanchi R, Honecker F, Bokemeyer C, Stonik V, von Amsberg G
PROTEOMICS. 2017;17(11):.

Frondoside A induces AIF-associated caspase-independent apoptosis in Burkitt lymphoma cells
Dyshlovoy S, Rast S, Hauschild J, Otte K, Alsdorf W, Madanchi R, Kalinin V, Silchenko A, Avilov S, Dierlamm J, Honecker F, Stonik V, Bokemeyer C, von Amsberg G
LEUKEMIA LYMPHOMA. 2017;58(12):2905-2915.

The Inhibitory Activity of Luzonicosides from the Starfish Echinaster luzonicus against Human Melanoma Cells
Malyarenko O, Dyshlovoy S, Kicha A, Ivanchina N, Malyarenko T, Carsten B, Gunhild v, Stonik V, Ermakova S
MAR DRUGS. 2017;15(7):.

Platinum-refractory germ cell tumors: an update on current treatment options and developments
Oing C, Alsdorf W, von Amsberg G, Oechsle K, Bokemeyer C
WORLD J UROL. 2017;35(8):1167-1175.

Monoubiquitination of histone H2B – a potential new target in treatment resistant germ cell tumors.
Oing C, Dyshlovoy S, Burandt E, Amsberg G, Honecker F, Bokemeyer C, Rothkamm K, Mansour W
ONCOL RES TREAT. 2017;40:95-96.

Systemische Behandlung des Harnblasenkarzinoms: Klassische Chemotherapie und neue Optionen
Oing C, von Amsberg G, Bokemeyer C
Im Focus Onkologie. 2017;20(9):50-56.

Monanchoxymycalin C with anticancer properties, new analogue of crambescidin 800 from the marine sponge Monanchora pulchra
Shubina L, Makarieva T, von Amsberg G, Denisenko V, Popov R, Dyshlovoy S
NAT PROD RES. 2017;1-8.

Unique prostate cancer-toxic polyketides from marine sediment-derived fungus Isaria felina
Smetanina O, Yurchenko A, Ivanets E, Kalinovsky A, Khudyakova Y, Dyshlovoy S, von Amsberg G, Yurchenko E, Afiyatullov S
J ANTIBIOT. 2017;70(7):856-858.

A nonrandomized, prospective, clinical study on the impact of circulating tumor cells on outcomes of urothelial carcinoma of the bladder patients treated with radical cystectomy with or without adjuvant chemotherapy
Soave A, Riethdorf S, Dahlem R, von Amsberg G, Minner S, Weisbach L, Engel O, Fisch M, Pantel K, Rink M
INT J CANCER. 2017;140(2):381-389.

Neue Aspekte in der Therapie des metastasierten Prostatakarzinoms
von Amsberg G, Bokemeyer C
DEUT MED WOCHENSCHR. 2017;142(15):1106-1110.

Metabolites of the Marine Fungus Aspergillus candidus KMM 4676 Associated with a Kuril Colonial Ascidian
Yurchenko A, Ivanets E, Smetanina O, Pivkin M, Dyshlovoi S, von Amsberg G, Afiyatullov S
Chemistry of Natural Compounds. 2017;53(4):747-749.

The marine triterpene glycoside frondoside A exhibits activity in vitro and in vivo in prostate cancer
Dyshlovoy S, Menchinskaya E, Venz S, Rast S, Amann K, Hauschild J, Otte K, Kalinin V, Silchenko A, Avilov S, Alsdorf W, Madanchi R, Bokemeyer C, Schumacher U, Walther R, Aminin D, Fedorov S, Shubina L, Stonik V, Balabanov S, Honecker F, von Amsberg G
INT J CANCER. 2016;138(10):2450-65.

Marine compound rhizochalinin shows high in vitro and in vivo efficacy in castration resistant prostate cancer
Dyshlovoy S, Otte K, Alsdorf W, Hauschild J, Lange T, Venz S, Bauer C, Bähring R, Amann K, Mandanchi R, Schumacher U, Schröder-Schwarz J, Makarieva T, Guzii A, Tabakmakher K, Fedorov S, Shubina L, Kasheverov I, Ehmke H, Steuber T, Stonik V, Bokemeyer C, Honecker F, von Amsberg G
ONCOTARGET. 2016;7(43):69703 - 69717.

Guanidine Alkaloids from the Marine Sponge Monanchora pulchra Show Cytotoxic Properties and Prevent EGF-Induced Neoplastic Transformation in Vitro
Dyshlovoy S, Tabakmakher K, Hauschild J, Shchekaleva R, Otte K, Guzii A, Makarieva T, Kudryashova E, Fedorov S, Shubina L, Bokemeyer C, Honecker F, Stonik V, von Amsberg G
MAR DRUGS. 2016;14(7):E133.

Anti-migratory activity of marine alkaloid monanchocidin A - proteomics-based discovery and confirmation
Dyshlovoy S, Venz S, Hauschild J, Tabakmakher K, Otte K, Madanchi R, Walther R, Guzii A, Makarieva T, Shubina L, Fedorov S, Stonik V, Bokemeyer C, Balabanov S, Honecker F, von Amsberg G
PROTEOMICS. 2016;16(10):1590-603.

Cabazitaxel overcomes cisplatin resistance in germ cell tumour cells
Gerwing M, Jacobsen C, Dyshlovoy S, Hauschild J, Rohlfing T, Oing C, Venz S, Oldenburg J, Oechsle K, Bokemeyer C, von Amsberg G, Honecker F
J CANCER RES CLIN. 2016;142(9):1979-94.

Melonoside A: An ω-Glycosylated Fatty Acid Amide from the Far Eastern Marine Sponge Melonanchora kobjakovae
Guzii A, Makarieva T, Denisenko V, Dmitrenok P, Kuzmich A, Dyshlovoy S, von Amsberg G, Krasokhin V, Stonik V
ORG LETT. 2016;18(14):3478-81.

Second Line Chemotherapy for Advanced and Metastatic Urothelial Carcinoma: Vinflunine and Beyond-A Comprehensive Review of the Current Literature
Oing C, Rink M, Oechsle K, Seidel C, von Amsberg G, Bokemeyer C
J UROLOGY. 2016;195(2):254-63.

Pharmacotherapeutic treatment of germ cell tumors - standard of care and recent developments
Oing C, Seidel C, von Amsberg G, Oechsle K, Bokemeyer C
EXPERT OPIN PHARMACO. 2016;17(4):545-60.

Absolute Configuration and Body Part Distribution of the Alkaloid 6-epi-Monanchorin from the Marine Polychaete Chaetopterus variopedatus
Shubina L, Makarieva T, Denisenko V, Dmitrenok P, Dyshlovoy S, von Amsberg G, Glazunov V, Silchenko A, Stonik V
NAT PROD COMMUN. 2016;11(9):1253-1257.

Pallidopenillines: Polyketides from the Alga-Derived Fungus Penicillium thomii Maire KMM 4675
Sobolevskaya M, Leshchenko E, Hoai T, Denisenko V, Dyshlovoy S, Kirichuk N, Khudyakova Y, Kim N, Berdyshev D, Pislyagin E, Kuzmich A, Gerasimenko A, Popov R, von Amsberg G, Antonov A, Afiyatullov S
J NAT PROD. 2016;79(12):3031-3038.

Activity of nintedanib in germ cell tumors
Steinemann G, Jacobsen C, Gerwing M, Hauschild J, Amsberg G, Höpfner M, Nitzsche B, Honecker F
ANTI-CANCER DRUG. 2016;27(2):89-98.

Fortschritte in der Therapie urogenitaler Tumoren
von Amsberg G, Bokemeyer C
Im Focus Onkologie. 2016;19(7-8):64.

Pretrichodermamides D-F from a Marine Algicolous Fungus Penicillium sp. KMM 4672
Yurchenko A, Smetanina O, Ivanets E, Kalinovsky A, Khudyakova Y, Kirichuk N, Popov R, Bokemeyer C, von Amsberg G, Chingizova E, Afiyatullov S, Dyshlovoy S
MAR DRUGS. 2016;14(7):E122.

Marine alkaloid Monanchocidin a overcomes drug resistance by induction of autophagy and lysosomal membrane permeabilization
Dyshlovoy S, Hauschild J, Amann K, Tabakmakher K, Venz S, Walther R, Guzii A, Makarieva T, Shubina L, Fedorov S, Stonik V, Bokemeyer C, Balabanov S, Honecker F, Amsberg G
ONCOTARGET. 2015;6(19):17328-41.

Systemic treatment of vulvar cancer
Mahner S, Prieske K, Grimm D, Trillsch F, Prieske S, von Amsberg G, Petersen C, Müller V, Jänicke F, Woelber L
EXPERT REV ANTICANC. 2015;15(6):629-37.

Beyond Bevacizumab: An Outlook to New Anti-Angiogenics for the Treatment of Ovarian Cancer
Mahner S, Woelber L, Müller V, Witzel I, Prieske K, Grimm D, von Amsberg G, Trillsch F
Front Oncol. 2015;5:211.

Management of advanced bladder cancer in the era of targeted therapies
Soave A, Engel O, von Amsberg G, Becker A, Dahlem R, Shariat S, Fisch M, Rink M
Minerva Urol Nefrol. 2015;67(2):103-15.

Viele innovative Substanzen: Kastrationsresistentes fortgeschrittenes Prostatakarzinom
von Amsberg G, Steuber T, Bokemeyer C
Deut Arzteblatt. 2015;112(20):8-10.

Amsberg G, Brümmendorf T
2014. Molekular zielgerichtete Therapie der chronischen myeloischen Leukämie (CML). Brümmendorf T, Koschmieder S (eds.). 1. ed. Bremen-London-Boston: Uni-Med, 71-75.

Aktuelle Therapiekonzepte bei kastrationsresistenten Prostatakarzinom
Amsberg G, Strölin P, Bokemeyer C, Steuber T
DEUT MED WOCHENSCHR. 2014;139(41):2086-90.

Aaptamines from the marine sponge Aaptos sp. display anticancer activities in human cancer cell lines and modulate AP-1-, NF-κB-, and p53-dependent transcriptional activity in mouse JB6 Cl41 cells
Dyshlovoy S, Fedorov S, Shubina L, Kuzmich A, Bokemeyer C, Amsberg G, Honecker F
BIOMED RES INT . 2014;2014:469309.

Clinical management of epithelial ovarian cancer during pregnancy
Grimm D, Woelber L, Trillsch F, Keller-v. Amsberg G, Mahner S
EUR J CANCER. 2014;50(5):963-971.

Bosutinib: a novel second-generation tyrosine kinase inhibitor
Isfort S, Amsberg G, Schafhausen P, Koschmieder S, Brümmendorf T
Recent Results Cancer Res. 2014;201:81-97.

Quinone-carbohydrate nonglucoside conjugates as a new type of cytotoxic agents: synthesis and determination of in vitro activity
Pelageev D, Dyshlovoy S, Pokhilo N, Denisenko V, Borisova K, Amsberg G, Bokemeyer C, Fedorov S, Honecker F, Anufriev V
EUR J MED CHEM. 2014;77:139-44.

Moderne Systemtherapie des fortgeschrittenen Prostatakarzinoms
Steuber T, Stroeilin P, Amsberg G
Onkologie heute. 2014;(04):22-25.

Bosutinib in the management of chronic myelogenous leukemia
Amsberg G, Schafhausen P
Biologics. 2013;7:115-22.

Combination of a proteomics approach and reengineering of meso scale network models for prediction of mode-of-action for tyrosine kinase inhibitors
Balabanov S, Wilhelm T, Venz S, Amsberg G, Scharf C, Pospisil H, Balabanov M, Barett C, Bokemeyer C, Walther R, Brümmendorf T, Schuppert A
PLOS ONE. 2013;8(1):e53668.

Targeting aurora kinases with danusertib (PHA-739358) inhibits growth of liver metastases from gastroenteropancreatic neuroendocrine tumors in an orthotopic xenograft model.
Fraedrich K, Schrader J, Ittrich H, von Amsberg G, Gontarewicz A, Matzat V, Kromminga A, Pace A, Moll J, Bläker M, Lohse A, Hörsch D, Brümmendorf T, Benten D
CLIN CANCER RES. 2012;18(17):4621-4632.

Novel aspects of therapy with the dual Src and Abl kinase inhibitor bosutinib in chronic myeloid leukemia.
von Amsberg G, Brümmendorf T
EXPERT REV ANTICANC. 2012;12(9):1121-1127.

Abcg2 overexpression represents a novel mechanism for acquired resistance to the multi-kinase inhibitor Danusertib in BCR-ABL-positive cells in vitro.
Balabanov S, Gontarewicz A, von Amsberg G, Raddrizzani L, Balabanov M, Bosotti R, Moll J, Jost E, Barett C, Rohe I, Bokemeyer C, Holyoake T, Brümmendorf T
PLOS ONE. 2011;6(4):19164.

Multi tyrosine kinase inhibitor dasatinib as novel cause of severe pre-capillary pulmonary hypertension?
Hennigs J, von Amsberg G, Baumann H, Honecker F, Kluge S, Bokemeyer C, Brümmendorf T, Klose H
BMC PULM MED. 2011;11:30.

von Amsberg G, Schafhausen P, Brümmendorf T
Recent Results Cancer Res. 2010;184:119-127.

Simultaneous targeting of Aurora kinases and Bcr-Abl kinase by the small molecule inhibitor PHA-739358 is effective against imatinib-resistant BCR-ABL mutations including T315I.
Gontarewicz A, Balabanov S, von Amsberg G, Colombo R, Graziano A, Pesenti E, Benten D, Bokemeyer C, Fiedler W, Moll J, Brümmendorf T
BLOOD. 2008;111(8):4355-4364.

PHA-680626 exhibits anti-proliferative and pro-apoptotic activity on Imatinib-resistant chronic myeloid leukemia cell lines and primary CD34+ cells by inhibition of both Bcr-Abl tyrosine kinase and Aurora kinases.
Gontarewicz A, Balabanov S, von Amsberg G, Panse J, Schafhausen P, Bokemeyer C, Fiedler W, Moll J, Brümmendorf T
LEUKEMIA RES. 2008;32(12):1857-1865.

Esophageal squamous cell carcinoma presenting with extensive skin lesions: a case report.
Iwanski G, Block A, von Amsberg G, Münch J, Claus S, Fiedler W, Bokemeyer C
J Med Case Rep. 2008;2:115.

Letzte Aktualisierung aus dem FIS: 18.08.2019 - 05:15 Uhr