Harriet Wikman-Kocher
Prof. Dr.
Harriet Wikman-Kocher
  • Scientist
Working area

Location

Campus Forschung N27 , 4th Floor, Room number 04.006
Languages
Swedish (Mother tongue)
English
German
Finnisch

Publications

Zurück
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011
  • 2009
  • 2008
  • 2007
Vor

Determination of PD-L1 Expression in Circulating Tumor Cells of NSCLC Patients and Correlation with Response to PD-1/PD-L1 Inhibitors
Janning M, Kobus F, Babayan A, Wikman H, Velthaus J, Bergmann S, Schatz S, Falk M, Berger L, Böttcher L, Päsler S, Gorges T, O'Flaherty L, Hille C, Joosse S, Simon R, Tiemann M, Bokemeyer C, Reck M, Riethdorf S, Pantel K, Loges S
CANCERS. 2019;11(6):.

EGFR and HER3 expression in circulating tumor cells and tumor tissue from non-small cell lung cancer patients
Scharpenseel H, Hanssen A, Loges S, Mohme M, Bernreuther C, Peine S, Lamszus K, Goy Y, Petersen C, Westphal M, Glatzel M, Riethdorf S, Pantel K, Wikman H
SCI REP-UK. 2019;9(1):7406.

Identification of a High-Level MET Amplification in CTCs and cfTNA of an ALK-Positive NSCLC Patient Developing Evasive Resistance to Crizotinib
Berger L, Janning M, Velthaus J, Ben-Batalla I, Schatz S, Falk M, Iglauer P, Simon R, Cao R, Forcato C, Manaresi N, Bramlett K, Buson G, Hanssen A, Tiemann M, Sauter G, Bokemeyer C, Riethdorf S, Reck M, Pantel K, Wikman H, Loges S
J THORAC ONCOL. 2018;13(12):e243-e246.

Stromal Caveolin-1 and Caveolin-2 Expression in Primary Tumors and Lymph Node Metastases
Gerstenberger W, Wrage M, Kettunen E, Pantel K, Anttila S, Steurer S, Wikman H
ANAL CELL PATHOL. 2018;2018:8651790.

Frequency of Circulating Tumor Cells (CTC) in Patients with Brain Metastases: Implications as a Risk Assessment Marker in Oligo-Metastatic Disease
Hanssen A, Riebensahm C, Mohme M, Joosse S, Velthaus J, Berger L, Bernreuther C, Glatzel M, Loges S, Lamszus K, Westphal M, Riethdorf S, Pantel K, Wikman H
CANCERS. 2018;10(12):E527.

Chromosomal Aberrations Associated with Sequential Steps of the Metastatic Cascade in Colorectal Cancer Patients
Joosse S, Souche F, Babayan A, Gasch C, Kerkhoven R, Ramos J, Fabre J, Riethdorf S, König A, Wikman H, Alix-Panabières C, Pantel K
CLIN CHEM. 2018;64(10):1505-1512.

Clinical relevance of cytoskeleton associated proteins for ovarian cancer
Schiewek J, Schumacher U, Lange T, Joosse S, Wikman H, Pantel K, Mikhaylova M, Kneussel M, Linder S, Schmalfeldt B, Oliveira-Ferrer L, Windhorst S
J CANCER RES CLIN. 2018;144(11):2195-2205.

Comparative study of whole genome amplification and next generation sequencing performance of single cancer cells
Babayan A, Alawi M, Gormley M, Müller V, Wikman H, McMullin R, Smirnov D, Li W, Geffken M, Pantel K, Joosse S
ONCOTARGET. 2017;8(34):56066-56080.

Strong fascin expression promotes metastasis independent of its F-actin bundling activity
Heinz L, Muhs S, Schiewek J, Grüb S, Nalaskowski M, Lin Y, Wikman H, Oliveira-Ferrer L, Lange T, Wellbrock J, Konietzny A, Mikhaylova M, Windhorst S
ONCOTARGET. 2017;8(66):110077-110091.

PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression
Hohensee I, Chuang H, Grottke A, Werner S, Schulte A, Horn S, Lamszus K, Bartkowiak K, Witzel I, Westphal M, Matschke J, Glatzel M, Jücker M, Pukrop T, Pantel K, Wikman H
ONCOTARGET. 2017;8(4):6155-6168.

PLA2G7 associates with hormone receptor negativity in clinical breast cancer samples and regulates epithelial-mesenchymal transition in cultured breast cancer cells
Lehtinen L, Vainio P, Wikman H, Huhtala H, Mueller V, Kallioniemi A, Pantel K, Kronqvist P, Kallioniemi O, Carpèn O, Iljin K
J Pathol Clin Res. 2017;3(2):123-138.

Circulating Tumour Cell Release after Cement Augmentation of Vertebral Metastases
Mohme M, Riethdorf S, Dreimann M, Werner S, Maire C, Joosse S, Bludau F, Mueller V, Neves R, Stoecklein N, Lamszus K, Westphal M, Pantel K, Wikman H, Eicker S
SCI REP-UK. 2017;7(1):7196.

Biology and clinical significance of circulating tumor cell subpopulations in lung cancer
O'Flaherty L, Wikman H, Pantel K
Transl Lung Cancer Res. 2017;6(4):431-443.

Nanoplatforms for Circulating Tumor Cell Detection in Lung Cancer
Wikman H, Pantel K
CLIN CHEM. 2017;63(8):1318-1320.

Role of HYAL1 expression in primary breast cancer in the formation of brain metastases
Witzel I, Marx A, Müller V, Wikman H, Matschke J, Schumacher U, Stürken C, Prehm P, Laakmann E, Schmalfeldt B, Milde-Langosch K, Oliveira-Ferrer L
BREAST CANCER RES TR. 2017;162(3):427-438.

Potential Involvement of Jagged1 in Metastatic Progression of Human Breast Carcinomas
Bednarz-Knoll N, Efstathiou A, Gotzhein F, Wikman H, Mueller V, Kang Y, Pantel K
CLIN CHEM. 2016;62(2):378-386.

Enumeration and molecular characterization of tumor cells in lung cancer patients using a novel in vivo device for capturing circulating tumor cells
Gorges T, Penkalla N, Schalk T, Joosse S, Riethdorf S, Tucholski J, Lucke K, Wikman H, Jackson S, Brychter N, von Ahsen O, Schumann C, Krahn T, Pantel K
CLIN CANCER RES. 2016;22(9):2197-206.

Characterization of different CTC subpopulations in non-small cell lung cancer
Hanssen A, Wagner J, Gorges T, Tänzer A, Uzunoglu F, Driemel C, Stoecklein N, Knoefel W, Angenendt S, Hauch S, Atanackovic D, Loges S, Riethdorf S, Pantel K, Wikman H
SCI REP-UK. 2016;6:28010.

A novel microfluidic platform for size and deformability based separation and the subsequent molecular characterization of viable circulating tumor cells
Hvichia G, Parveen Z, Wagner C, Janning M, Quidde J, Stein A, Müller V, Loges S, Neves R, Stoecklein N, Wikman H, Riethdorf S, Pantel K, Gorges T
INT J CANCER. 2016;138(12):2894-904.

Breast cancer brain metastases:biology and new clinical perspectives
Witzel I, Oliveira-Ferrer L, Pantel K, Müller V, Wikman H
BREAST CANCER RES. 2016;18(1):8.

Disseminated Tumor Cells Persist in the Bone Marrow of Breast Cancer Patients through Sustained Activation of the Unfolded Protein Response
Bartkowiak K, Kwiatkowski M, Buck F, Gorges T, Nilse L, Assmann V, Andreas A, Müller V, Wikman H, Riethdorf S, Schlüter H, Pantel K
CANCER RES. 2015;75(24):5367-77.

Stromal expression of ALDH1 in human breast carcinomas indicates reduced tumor progression
Bednarz-Knoll N, Nastały P, Żaczek A, Stoupiec M, Riethdorf S, Wikman-Kocher H, Müller V, Skokowski J, Szade J, Sejda A, Wełnicka-Jaśkiewicz M, Pantel K
ONCOTARGET. 2015;6(29):26789-803.

Detection of Circulating Tumor Cells in Non-Small Cell Lung Cancer
Hanssen A, Loges S, Pantel K, Wikman-Kocher H
Front Oncol. 2015;5:Art. 207.

Distribution and prognostic relevance of tumor-infiltrating lymphocytes (TILs) and PD-1/PD-L1 immune checkpoints in human brain metastases
Harter P, Bernatz S, Scholz A, Zeiner P, Zinke J, Kiyose M, Blasel S, Beschorner R, Senft C, Bender B, Ronellenfitsch M, Wikman-Kocher H, Glatzel M, Meinhardt M, Juratli T, Steinbach J, Plate K, Wischhusen J, Weide B, Mittelbronn M
ONCOTARGET. 2015;6(38):40836-40849.

Relevance of βGal-βGalNAc-containing glycans and the enzymes involved in their synthesis for invasion and survival in breast cancer patients
Milde-Langosch K, Schütze D, Oliveira-Ferrer L, Wikman-Kocher H, Müller V, Lebok P, Pantel K, Schröder C, Witzel I, Schumacher U
BREAST CANCER RES TR. 2015;151(3):515-28.

Suppression of early hematogenous dissemination of human breast cancer cells to bone marrow by retinoic acid induced 2
Werner S, Brors B, Eick J, Marques E, Pogenberg V, Parret A, Kemming D, Wood A, Edgren H, Neubauer H, Streichert T, Riethdorf S, Bedi U, Baccelli I, Jücker M, Eils R, Fehm T, Trumpp A, Johnsen S, Klefstrom J, Wilmanns M, Müller V, Pantel K, Wikman-Kocher H
CANCER DISCOV. 2015;5(5):506-19.

Iroquois homeobox 2 suppresses cellular motility and chemokine expression in breast cancer cells
Werner S, Stamm H, Pandjaitan M, Kemming D, Brors B, Pantel K, Wikman H
BMC CANCER. 2015;15(1):896.

Identification of HERC5 and its potential role in NSCLC progression
Wrage M, Hagmann W, Kemming D, Uzunoglu F, Riethdorf S, Harms-Effenberger K, Westphal M, Lamszus K, Kim S, Becker N, Izbicki J, Sandoval J, Esteller M, Pantel K, Risch A, Wikman-Kocher H
INT J CANCER. 2015;136(10):2264-72.

Increased serum levels of circulating exosomal microRNA-373 in receptor-negative breast cancer patients
Eichelser C, Stückrath I, Müller V, Milde-Langosch K, Wikman-Kocher H, Pantel K, Schwarzenbach H
ONCOTARGET. 2014;5(20):9650-63.

PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis
LeBleu V, O'Connell J, Gonzalez Herrera K, Wikman-Kocher H, Pantel K, Haigis M, de Carvalho F, Damascena A, Domingos Chinen L, Rocha R, Asara J, Kalluri R
NAT CELL BIOL. 2014;16(10):992-1003.

Loss of 4q21.23-22.1 is a Prognostic Marker for Disease Free and Overall Survival in Non-Small Cell Lung Cancer
Uzunoglu F, Dethlefsen E, Hanssen A, Wrage M, Deutsch L, Harms-Effenberger K, Vashist Y, Reeh M, Sauter G, Simon R, Bockhorn M, Pantel K, Izbicki J, Wikman-Kocher H
PLOS ONE. 2014;9(12):e113315.

Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients
Wikman-Kocher H, Westphal L, Schmid F, Pollari S, Kropidlowski J, Sielaff-Frimpong B, Glatzel M, Matschke J, Westphal M, Iljin K, Huhtala H, Terracciano L, Kallioniemi A, Sauter G, Müller V, Witzel I, Lamszus K, Kemming D, Pantel K
ONCOTARGET. 2014;5(10):3076-3087.

Frequent genetic alterations in EGFR- and HER2-driven pathways in breast cancer brain metastases
Hohensee I, Lamszus K, Riethdorf S, Meyer-Staeckling S, Glatzel M, Matschke J, Witzel I, Westphal M, Brandt B, Müller V, Pantel K, Wikman H
AM J PATHOL. 2013;183(1):83-95.

Accumulation of genomic alterations in 2p16, 9q33.1 and 19p13 in lung tumours of asbestos-exposed patients
Nymark P, Aavikko M, Mäkilä J, Ruosaari S, Hienonen-Kempas T, Wikman H, Salmenkivi K, Pirinen R, Karjalainen A, Vanhala E, Kuosma E, Anttila S, Kettunen E
MOL ONCOL. 2013;7(1):29-40.

VEGFR-2, CXCR-2 and PAR-1 germline polymorphisms as predictors of survival in pancreatic carcinoma
Uzunoglu F, Kolbe J, Wikman H, Güngör C, Bohn B, Nentwich M, Reeh M, König A, Bockhorn M, Kutup A, Mann O, Izbicki J, Vashist Y
ANN ONCOL. 2013;24(5):1282-90.

C-X-C motif receptor 2, endostatin and proteinase-activated receptor 1 polymorphisms as prognostic factors in NSCLC
Uzunoglu F, Yavari N, Bohn B, Nentwich M, Reeh M, Pantel K, Perez D, Tsui T, Bockhorn M, Mann O, Izbicki J, Wikman H, Vashist Y
LUNG CANCER. 2013;81(1):123-9.

Opposite roles of FOXA1 and NKX2-1 in lung cancer progression.
Deutsch L, Wrage M, Koops S, Glatzel M, Uzunoglu F, Kutup A, Hinsch A, Sauter G, Izbicki J, Pantel K, Wikman H
GENE CHROMOSOME CANC. 2012;51(6):618-629.

15-Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition, and promotes cell migration in cultured breast cancer cells.
Lehtinen L, Vainio P, Wikman H, Reemts J, Hilvo M, Issa R, Pollari S, Brandt B, Oresic M, Pantel K, Kallioniemi O, Iljin K
J PATHOL. 2012;226(4):674-686.

Circulating tumor-derived biomarkers in lung cancer.
Tänzer A, Alix-Panabières C, Wikman H, Pantel K
J THORAC DIS. 2012;4(5):448-449.

Vascular endothelial growth factor receptor 2 gene polymorphisms as predictors for tumor recurrence and overall survival in non-small-cell lung cancer.
Uzunoglu F, Kaufmann C, Wikman H, Güngör C, Bohn B, Nentwich M, Reeh M, Pantel K, Bockhorn M, Kutup A, Mann O, Izbicki J, Vashist Y
ANN SURG ONCOL. 2012;19(7):2159-2168.

Relevance of PTEN loss in brain metastasis formation in breast cancer patients.
Wikman H, Lamszus K, Detels N, Uslar L, Wrage M, Benner C, Hohensee I, Ylstra B, Eylmann K, Zapatka M, Sauter G, Kemming D, Glatzel M, Müller V, Westphal M, Pantel K
BREAST CANCER RES. 2012;14(2):49.

Clinical relevance of loss of 11p15 in primary and metastatic breast cancer: association with loss of PRKCDBP expression in brain metastases.
Wikman H, Sielaff-Frimpong B, Kropidlowski J, Witzel I, Milde-Langosch K, Sauter G, Westphal M, Lamszus K, Pantel K
PLOS ONE. 2012;7(10):47537.

Clinical relevance of loss of 11p15 in primary and metastatic breast cancer: association with loss of PRKCDBP expression in brain metastases
Wikman H, Sielaff-Frimpong B, Kropidlowski J, Witzel I, Milde-Langosch K, Sauter G, Westphal M, Lamszus K, Pantel K, Wikman-Kocher H
PLOS ONE. 2012;7(10):e47537.

Biologic role of activated leukocyte cell adhesion molecule overexpression in breast cancer cell lines and clinical tumor tissue.
Hein S, Müller V, Köhler N, Wikman H, Krenkel S, Streichert T, Schweizer M, Riethdorf S, Assmann V, Henningsen M, Beck K, Issa R, Jänicke F, Pantel K, Milde-Langosch K
BREAST CANCER RES TR. 2011;129(2):347-360.

Meta- and pooled analysis of GSTP1 polymorphism and lung cancer: a HuGE-GSEC review.
Cote M, Chen W, Smith D, Benhamou S, Bouchardy C, Butkiewicz D, Fong K, Gené M, Hirvonen A, Kiyohara C, Larsen J, Lin P, Raaschou-Nielsen O, Povey A, Reszka E, Risch A, Schneider J, Schwartz A, Sorensen M, Figueras J, Tokudome S, Pu Y, Yang P, Wenzlaff A, Wikman H, Taioli E
AM J EPIDEMIOL. 2009;169(7):802-814.

DNA copy number loss and allelic imbalance at 2p16 in lung cancer associated with asbestos exposure.
Kettunen E, Aavikko M, Nymark P, Ruosaari S, Wikman H, Vanhala E, Salmenkivi K, Pirinen R, Karjalainen A, Kuosma E, Anttila S
BRIT J CANCER. 2009;100(8):1336-1342.

Molecular alterations at 9q33.1 and polyploidy in asbestos-related lung cancer.
Nymark P, Kettunen E, Aavikko M, Ruosaari S, Kuosma E, Vanhala E, Salmenkivi K, Pirinen R, Karjalainen A, Knuutila S, Wikman H, Anttila S
CLIN CANCER RES. 2009;15(2):468-475.

Genomic profiles associated with early micrometastasis in lung cancer: relevance of 4q deletion.
Wrage M, Ruosaari S, Eijk P, Kaifi J, Hollmén J, Yekebas E, Izbicki J, Brakenhoff R, Streichert T, Riethdorf S, Glatzel M, Ylstra B, Pantel K, Wikman H
CLIN CANCER RES. 2009;15(5):1566-1574.

Molecular and genetic changes in asbestos-related lung cancer.
Nymark P, Wikman H, Hienonen-Kempas T, Anttila S
CANCER LETT. 2008;265(1):1-15.

Review: Biological relevance of disseminated tumor cells in cancer patients.
Riethdorf S, Wikman H, Pantel K
INT J CANCER. 2008;123(9):1991-2006.

Pathways affected by asbestos exposure in normal and tumour tissue of lung cancer patients.
Ruosaari S, Hienonen-Kempas T, Puustinen A, Sarhadi V, Hollmén J, Knuutila S, Saharinen J, Wikman H, Anttila S
BMC MED GENOMICS. 2008;1:55.

Cancer micrometastasis and tumour dormancy.
Wikman H, Vessella R, Pantel K
APMIS. 2008;116(7-8):754-770.

Gene expression and copy number profiling suggests the importance of allelic imbalance in 19p in asbestos-associated lung cancer.
Wikman H, Ruosaari S, Nymark P, Sarhadi V, Saharinen J, Vanhala E, Karjalainen A, Hollmén J, Knuutila S, Anttila S
ONCOGENE. 2007;26(32):4730-4737.

Letzte Aktualisierung aus dem FIS: 11.11.2019 - 05:48 Uhr