Prof. Dr. Dr. Marc Hirt

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Marc Hirt is professor of pharmacology at the University Medical Center Hamburg-Eppendorf. He graduated from the medical schools of Heidelberg and Freiburg, Germany, in 2006, the same year he received his Doctorate in Medicine. After completing two years of residency in anesthesiology at the University Medical Center-Hamburg, he decided to fully dedicate himself to research and medical education. In 2008, he joined the Institute of Experimental Pharmacology and Toxicology (Prof. Eschenhagen) as group leader. He became a board-certified specialist in Clinical Pharmacology in 2013 and in Pharmacology and Toxicology in 2016. He received his PhD from the University of Hamburg in 2016. His research focuses on engineered heart tissue (EHT), a versatile 3D-format of cardiomyocytes derived from human induced pluripotent stem cells. Through mechanical or pharmacological stimulation of EHT, his team developed a human model of cardiac hypertrophy. As a byproduct of this work, his team also established differentiation strategies for other key cardiac cell types - including fibroblasts, smooth muscle cells, endothelial cells, and macrophages - and successfully integrated them into EHTs. This expanded EHT's utility, for example, in modeling fibrotic and inflammatory changes. In 2025, he joined the UCCS/UHZ (Prof. Fabritz/Prof. Kirchhof).

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m.hirt@uke.de

Publications please visit Pubmed