Working Group Children’s Heart Clinic


Name: Prof. Dr. med. Carsten Rickers
Clinic/Institute: Children’s Heart Clinic, (Adult Congenital Heart Disease (ACHD)
Email: c.rickers@uke.de
Phone: +49 (0) 40 7410 - 54832

Research Focus and Main research questions

MicroRNA (abbreviated miRNA) is a small single-stranded non-coding RNA molecule that functions in RNA silencing and post-transcriptional regulation of gene expression. Circulating miRNAs are released into body fluids including blood and cerebrospinal fluid and have the potential to be available as biomarkers in a number of diseases. The focus of our research is the evaluation of specific miRNA’s in patients with tetralogy of fallot (TOF).

Research Projects
MiRNA in patients with unrepaired and repaired TOF

Main research questions
 Specific miRNA levels may predict outcome in patients with unrepaired and repaired TOF and be associated with clinical signs of heart failure, echocardiography and MRI findings.

  • Methods
  • Methods

    Methods:

    Evaluation of miRNA (blood and tissue samples), clinical and laboratory signs, as well as specific echocardiographic parameters for heart failure and MRI in patients with unrepaired and repaired TOF.

  • Publications:

  • Recent Funding:

Research Team

PD N. Lang
(Pediatric Cardiology)

Dr. F. Neumann
(Pediatric Cardiology)

Dr. D. Biermann
(Congenital and Pediatric Heart Surgery)

PD C. Sinning
(Pediatric Cardiology), Adult Congenital Heart Disease (ACHD))

Dr. E. Zengin-Sahm
(Pediatric Cardiology, Adult Congenital Heart Disease (ACHD))

Prof. C. Rickers
(Adult Congenital Heart Disease (ACHD))