DE
Area B - Target characterization
What are potential therapeutic targets in the virus and/or host?
Through the process of identifying the crucial interactions involved in infection processes, relevant targets can be selected. These include essential viral and cellular enzymes, factors and complexes formed among viral proteins or between viral and host proteins. The local access to state-of-the-art biophysics and structural biology infrastructure such as the high-end cryoEM facility at the Centre for Structural Systems Biology (CSSB) under BSL2 and BSL3 conditions will enable the characterization of new targets involved in critical interactions. The insights gained can form the starting point for developing new intervention options.
Projects Research Area B
