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Core Facilities
Cutting-Edge Technologies for Cancer Research
Core Facilities with expert support are available to all research groups at UKE.
The core facilities of the University Cancer Center Hamburg (UCC Hamburg) offer all research groups at UKE state-of-the-art technology services and expert advice. Projects carried out by researchers at UCC Hamburg are given priority. Under certain circumstances, external users may also be granted access. Access to technology platforms can be provided for collaborative projects.
For details on the services offered and to make an appointment, please contact the managers of the individual core facilities and platforms listed below.
Contact us now
If you have any questions about the core facilities at UCC Hamburg, please contact:
Our Core Facilities and Technologies
Imaging
This platform's services are available as a scientific collaboration for scientists at the UKE/UCC Hamburg. For further information, please contact:
Dr. Philippe Schafhausen
UCC Hamburg/Department of Oncology and Hematology
Cytogenetic analyses can be performed in scientific collaboration with Prof. Dierlamm. For details, please contact:
Prof. Dr. Dr. Judith Dierlamm
Department of Oncology and Hematology
This core facility is managed by the Vice Dean's Office for Research under the direction of Prof. Fehse. For details on the services offered and prices, please visit the website or contact Regine Thiele, the coordinator of this core facility:
Regine Thiele, Graduate engineer
Vice Dean's Office for Research
The IVIS 200 detects luminescence and fluorescence signals and is ideal for investigating organ-specific reporter gene expression. The system is well suited for monitoring tumors and metastases. Genetically modified models are required for luminescence imaging. The analysis is performed by our staff. The costs are paid as a service fee (including costs for luminescence substrate, anesthetics for the measurement, and service fee for our technician). Please contact us for further details:
Michael Horn
The SmART+ precision X-ray system enables cross-sectional imaging (and precise therapeutic irradiation) of small animal models with two different μCT imaging modalities (50μm and 20μm spatial resolution) and simultaneous in vivo bioluminescence imaging. Please feel free to contact us:
PD Dr. Dr. Thorsten Frenzel
In collaboration with the Department of Tumor Biology headed by Prof. Pantel, individual cells can be analyzed using high-end technologies. For further information, please contact:
Prof. Dr. Klaus Pantel
The MRI platform is located in the Department of Diagnostic and Interventional Radiology and is headed by Dr. Kaul. The preclinical MRI scanner offers high diagnostic accuracy and superior soft tissue contrast. MRI is non-invasive and ideal for longitudinal studies. For further information about the system and its application, please contact:
Dr. rer. nat. Michael Kaul
This core facility is operated by the Office of the Vice Dean for Research.
This core facility performs high-quality histological analyses of cell and tissue preparations from mice. It is one of the core facilities of the Office of the Vice Dean for Research.
Prof. Eschenhagen's group is making this technology available to scientists at UCC Hamburg/UKE as part of a scientific collaboration. For further information, please contact:
Prof. Dr. Thomas Eschenhagen
Omics Core Facilities
The analysis is performed using the Ilumina iScan Array system. For further information, please contact the head of the department, Prof. Schüller.
Prof. Dr. Ullrich Schüller
Institute of Neuropathology and Research Institute Children's Cancer Center Hamburg
The service is offered through scientific collaboration with the Institute of Human Genetics, headed by Prof. Kubisch. For details on the available technologies, please contact:
Dr. rer. nat. Michael Kutsche
Institute of Human Genetics
Based on protein kinase array technology, users can investigate the activity of kinase families in cell and tissue lysates. Global tyrosine (or serine/threonine) kinase activity patterns can be determined. For details, please contact:
PD Dr. Malte Kriegs
Laboratory of Radiobiology & Experimental Radiation Oncology
This core facility is one of the core units of the UKE Vice Dean's Office for Research.
Additional technologies such as chromatography and mass spectrometry can be provided in cooperation. Please feel free to contact:
Prof. Dr. Hartmut Schlüter
Institute for Clinical Chemistry/Central Laboratories
The Institute of Clinical Chemistry supports scientists in analyzing the metabolomic patterns of their samples. For details on possible collaboration, please contact:
Dr. rer. nat. Verena Horneffer-van der Sluis
Institute of Clinical Chemistry
This core facility is open to all scientists at the UKE and other interested parties. It offers the use of the nanoString® nCounter Analysis System for the direct multiplex measurement of analytes with high-precision, high-sensitivity digital barcode technology.
This facility has an Illumina MiSeq for targeted DNA sequencing and targeted RNA sequencing for targeted gene expression analysis. Even small genomes can be detected. Whole genome, exome, or transcriptome sequencing cannot be performed. For further details and prices, please contact Dr. Akyüz:
Dr. rer. nat. Nuray Akyüz
Department of Oncology and Hematology
Genetic Modification and Radiation Therapy
Various applications can be implemented based on CRISPR/Cas9-based genome editing technology. The service is provided as a scientific collaboration and includes support during project planning, strategy development, genotyping, colony maintenance, and injection. For details, please contact:
Prof. Dr. Boris Fehse
Department of Stem Cell Transplantation
Researchers have access to an isotope laboratory and an irradiation facility on the UKE campus. Both are managed by the Office of the Vice Dean for Research. For further details and instructions, please follow the links.
In vitro X-ray irradiation and assays for clonogenic cell survival, chromosomal aberrations, DNA damage and repair, signaling pathways, and cell cycle/replication dynamics are available through scientific collaboration with the
If you are interested, please contact
The SmART+ precision X-ray system enables precise local ablation radiation therapy for tumors in small animal models. Sectional imaging with two different μCT imaging modalities (50 μm and 20 μm spatial resolution), multiple collimators for beam shaping, Monte Carlo-based radiation planning, and a high-precision treatment table enable us to mimic clinical image-guided radiation therapy. Furthermore, bioluminescence imaging in the treatment position is possible, enabling functional tumor imaging. If you are interested, please contact:
PD Dr. Dr. Thorsten Frenzel
Department of Radiation Therapy
This core facility is located at the Center for Molecular Neurobiology Hamburg (ZMNH).
Please contact for further infromation:
Anne-Marie Marzesco
This core facility is operated by the Office of the Vice Dean for Research.
Biobank and Biospecimen Resources
A broad collection of FFPE tissue and well-selected TMA (tissue microarray) is available at the Institute of Pathology under the direction of Prof. Sauter. For details on the terms of use, please contact:
Prof. Dr. Ronald Simon
Institute of Pathology
The UCC Hamburg has established a biobank containing biological samples from patients suffering from hematological and solid tumors. For further information on the samples available in the UCC Hamburg Biobank and other oncological sample collections, please contact the coordinator of the UCC Hamburg Biobank:
Dr. rer. nat. Britta Fritzsche
The tumor-on-a-chip is a microbioreactor. Human tumor cells grow in it as tumoroids, enabling various drugs to be tested and their influence on tumor cell growth to be studied. For further information on this technology, please contact:
Prof. Dr. Manfred Jücker
Institute of Biochemistry and Signaltransduction
Preclinical cancer models provide a platform for investigating tumor biology, identifying biomarkers, testing potential therapies, developing personalized medical approaches, investigating resistance mechanisms, and potentially reducing dependence on animal testing. In the
Please contact
Data Science
The mission of this UCC Hamburg Core Facility, headed by Dr. Bartels, is to evaluate biomedical and health data using quantitative and computer-assisted analyses. We apply methods of biomedical informatics and biostatistics to integrate and analyze data from researchers at UCC Hamburg. The facility supports scientists and clinicians in the areas of clinical data integration, medical informatics, biostatistics, and data modeling.
If you are interested, please contact:
Dr. Stefan Bartels
Jasmin Carus
The UCC Hamburg Study Center offers support in the implementation and management of clinical study data. For further information, please contact PD Dr. Block or Prof. Weisel and visit the
PD Dr. Andreas Block, MBA
Prof. Dr. Katja Weisel
The Center for Biomedical AI at the UKE has set itself the goal of developing and applying state-of-the-art algorithms to predict, understand, and cure diseases. It brings together the expertise of AI and medical specialists at the UKE to bring next-generation software solutions to the clinic. As a hub for biomedical AI, we collaborate with academic institutions and industry partners and provide starting points and guidance for AI start-ups. At bAIome, we also strive to train the next generation of AI experts, medical students, and clinicians. For further information, please contact Dr. Reinicke-Vogt or visit the
Dr. Anna Reinicke-Vogt
Scientific coordinator at bAIome Center for Biomedical AI, UKE
The Department of Medical Biometry and Epidemiology offers consulting services and analytical support for scientists at the UKE. Further information and contact details can be found here
This core facility is part of the Office of the Vice Dean for Research and is headed by Dr. Alawi.
Dr. Malik Alawi, M. Sc.
Further information on research data management can be found
Further
The Antibody Core Facility offers expertise in recombinant antibody and nanobody technologies. Nanobodies are soluble variable domains derived from heavy chain antibodies that occur naturally in llamas and other camelids. For further information and user guidelines, please contact Prof. Koch-Nolte or visit the
Prof. Dr. med. Friedrich Koch-Nolte
institute of Immunology
Researchers at UCC Hamburg/UKE have access to NMR technology. The platform is available at the Institute of Chemistry at the University of Hamburg. For details on the application and limitations of the technology, please contact:
Department of NMR-Spectroscopy, Division of Chemistry
University of Hamburg
NMR-Spectroscopy
Martin-Luther-King-Platz 6
20146 Hamburg
The
Please contact
PIRL- and NIRL-based technologies enable the targeted removal of very small tissue samples, thus providing spatial resolution for the subsequent analysis of biomolecules, e.g., using mass spectrometry. Interested scientists can obtain further information from the following contacts:
Dr. Jan Hahn
Prof. Hartmut Schlüter
These platforms provide scientists at the University of Hamburg and the UKE with access to state-of-the-art methods, thereby creating an integrative research environment for excellent individual and collaborative research and promoting the interdisciplinary and synergistic use of technologies. Further details and contact persons can be found at the following links:
If you are interested in the technology platforms of our academic cooperation partners at the University Cancer Center Schleswig-Holstein (UCCSH) or would like to use the research infrastructure available there, you can find further information here:
Further Information
Do you have any questions or would you like to make an appointment? Here you will find our contact details for UCC Hamburg.
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