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Publikationen in der Andrologie

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2020

Ex vivo testis explant culture of human intrapubertal testicular tissue
Aden N, Soave A, Kordes U, Bleeke M, Salzbrunn A, von Kopylow K
J Reprodmed Endokrinol. 2020;14(1):39 - 40.

2019

The DNA methylation profile of human spermatogonia at single-cell- and single-allele-resolution refutes its role in spermatogonial stem cell function and germ cell differentiation
Fend-Guella D, von Kopylow K, Spiess A, Schulze W, Salzbrunn A, Diederich S, El Hajj N, Haaf T, Zechner U, Linke M
MOL HUM REPROD. 2019;25(6):283-294.

Expression of miRNA-371a-3p in seminal plasma and ejaculate is associated with sperm concentration
Radtke A, Dieckmann K, Grobelny F, Salzbrunn A, Oing C, Schulze W, Belge G
ANDROLOGY-US. 2019;7(4):469-474.

2018

Dynamics, ultrastructure and gene expression of human in-vitro organized testis cells from testicular sperm extraction biopsies
von Kopylow K, Schulze W, Salzbrunn A, Schaks M, Schäfer E, Roth B, Schlatt S, Spiess A
MOL HUM REPROD. 2018;24(3):123-134.

Methylation profiling of human Spermatogonial Stem Cells (HSSCs) at single allele resolution
Fend D, von Kopylow K, Schulze W, Salzbrunn A, Spiess AN, El Hajj N, Haaf T, Zechner U, Linke M
MED GENET-BERLIN. 2018;30(1):135.

Das DNA-Methylierungsprofil humaner, aus TESE-Biopsien isolierter Spermatogonien auf Einzelzell- bzw. Einzel-Allel-Ebene
von Kopylow K, Fend D, Spiess A, Schulze W, Salzbrunn A, Diederich S, El Hajj N, Haaf T, Zechner U, Linke M
J Reprodmed Endokrinol. 2018;15(Supplementum 1):2-3.

In-vitro-Reorganisation adulter humaner Hodenzellen in TESE-Biopsien im dreischichtigen 3D-Gradientensystem
von Kopylow K, Schulze W, Salzbrunn A, Alves-Lopes J, Stukenborg J, Spiess A
J Reprodmed Endokrinol. 2018;15(Supplementum 1):3.

2017

Human spermatogonial markers
von Kopylow K, Spiess A
STEM CELL RES. 2017;25:300-309.

Zelluläre Komposition, Ultrastruktur, Genexpression und Dynamik humaner in vitro-reorganisierter adulter Hodenzellen
von Kopylow K, Schulze W, Salzbrunn A, Schaks M, Schäfer E, Schlatt S, Roth B, Spiess A
J Reprodmed Endokrinol. 2017;14(5):233 - 234.

2016

Varicocele Is Associated with Impaired Semen Quality and Reproductive Hormone Levels: A Study of 7035 Healthy Young Men from Six European Countries
Damsgaard J, Joensen U, Carlsen E, Erenpreiss J, Blomberg Jensen M, Matulevicius V, Zilaitiene B, Olesen I, Perheentupa A, Punab M, Salzbrunn A, Toppari J, Virtanen H, Juul A, Skakkebæk N, Jørgensen N
EUR UROL. 2016;70(6):1019-1029.

Compensated reduction in Leydig cell function is associated with lower semen quality variables: a study of 8182 European young men
Jørgensen N, Joensen U, Toppari J, Punab M, Erenpreiss J, Zilaitiene B, Paasch U, Salzbrunn A, Fernandez M, Virtanen H, Matulevicius V, Olea N, Jensen T, Petersen J, Skakkebæk N, Andersson A
HUM REPROD. 2016;31(5):947-57.

Comment on "Absence of sperm RNA elements correlates with idiopathic male infertility"
Cappallo-Obermann H, Spiess A
SCI TRANSL MED. 2016;8(353):353tc1.

Reorganisation testikulärer Strukturen bei In-vitro-kultivierten Zellen aus dem humanen adulten normogonadotropen Hoden mit vollständiger Spermatogenese
von Kopylow K, Schlatt S, Schulze W, Salzbrunn A, Spiess A
J Reprodmed Endokrinol. 2016;13(4):151.

Isolation and gene expression analysis of single potential human spermatogonial stem cells
von Kopylow K, Schulze W, Salzbrunn A, Spiess A
MOL HUM REPROD. 2016;22(4):229-39.

2014

Alcohol and male reproductive health: a cross-sectional study of 8344 healthy men from Europe and the USA
Jensen T, Swan S, Jørgensen N, Toppari J, Redmon B, Punab M, Drobnis E, Haugen T, Zilaitiene B, Sparks A, Irvine D, Wang C, Jouannet P, Brazil C, Paasch U, Salzbrunn A, Skakkebæk N, Andersson A
HUM REPROD. 2014;29(8):1801-9.

Einzelzellmarkierung und -isolierung potenzieller humaner spermatogonialer Stammzellen
von Kopylow K, Spiess A, Schulze W
J Reprodmed Endokrinol. 2014;11(4):189.

Visual selection of human potential spermatogonial stem cells by bead-tagging
von Kopylow K, Spiess A, Schulze W
2014. 18th ETW European Testis Workshop. IV-41.

2013

Fold-change correction values for testicular somatic transcripts in gene expression studies of human spermatogenesis
Cappallo-Obermann H, Feig C, Schulze W, Spiess A
HUM REPROD. 2013;28(3):590-598.

The sperm protamine mRNA ratio as a clinical parameter to estimate the fertilizing potential of men taking part in an ART programme
Rogenhofer N, Dansranjavin T, Schorsch M, Spiess A, Wang H, von Schönfeldt V, Cappallo-Obermann H, Baukloh V, Yang H, Paradowska A, Chen B, Thaler C, Weidner W, Schuppe H, Steger K
HUM REPROD. 2013;28(4):969-78.

New Approaches to Diagnosing Male Infertility: Part I: Microarray Analysis of Testicular Biopsy Specimens from Men with Intact and Impaired Spermatogenesis.
Spiess A, Schulze W
2013. Atlas on the Human Testis. Jezek D (Hrsg.). 1. Aufl. Springer, 253-261.

Kolokalisation von FGF9 und FGFR3 in adulten humanen Spermatogonien
von Kopylow K, Spiess A, Schulze W, Kirchhoff C
J Reprodmed Endokrinol. 2013;10(5-6):330.

2012

Fibroblast growth factor receptor 3 is highly expressed in rarely dividing human type A spermatogonia.
von Kopylow K, Staege H, Schulze W, Will H, Kirchhoff C
Histochem Cell Biol. 2012;138(5):759-772.

Differential marker protein expression specifies rarefaction zone-containing human A (dark) spermatogonia.
von Kopylow K, Staege H, Spiess A, Schulze W, Will H, Primig M, Kirchhoff C
REPRODUCTION. 2012;143(1):45-57.

FGFR3 as a potential marker for human spermatogonial stem cells
von Kopylow K, Spiess A, Schulze W, Staege H, Will H, Kirchhoff C
J Reprodmed Endokrinol. 2012;9(5):365.

2011

Highly purified spermatozoal RNA obtained by a novel method indicates an unusual 28S/18S rRNA ratio and suggests impaired ribosome assembly.
Capallo-Obermann H, Schulze W, Jastrow H, Baukloh V, Spiess A
MOL HUM REPROD. 2011;17(11):669-678.

A one-step real-time multiplex PCR for screening Y-chromosomal microdeletions without downstream amplicon size analysis.
Kozina V, Capallo-Obermann H, Gromoll J, Spiess A
PLOS ONE. 2011;6(8):23174.

2010

A biopsy sample reduction approach to identify significant alterations of the testicular transcriptome in the presence of Y-chromosomal microdeletions that are independent of germ cell composition
Cappallo-Obermann H, von Kopylow K, Schulze W, Spiess A
HUM MOL GENET. 2010;128(4):421-31.

Screening for biomarkers of spermatogonia within the human testis: a whole genome approach.
von Kopylow K, Kirchhoff C, Jezek D, Schulze W, Feig C, Primig M, Steinkraus V, Spiess A
HUM REPROD. 2010;25(5):1104-1112.

2009

Expression of SNURF-SNRPN upstream transcripts and epigenetic regulatory genes during human spermatogenesis.
Wawrzik M, Spiess A, Herrmann R, Buiting K, Horsthemke B
EUR J HUM GENET. 2009.

Molekulare Charakterisierung humaner Spermatogonien
von Kopylow K, Kirchhoff C, Schulze W, Spiess A
J Reprodmed Endokrinol. 2009;6(5):225.

2008

Semen quality in sub-fertile range for a significant proportion of young men from the general German Population: a co-ordinated, controlled study of 791 men from Hamburg and Leipzig
Paasch U, Salzbrunn A, Glander H, Plambeck K, Salzbrunn H, Grunewald S, Stucke J, Vierula M, Skakkebaek N, Jørgensen N
INT J ANDROL. 2008;31(2):93-102.

1996

Pregnancy after intracytoplasmic sperm injection of spermatozoa extracted from frozen-thawed testicular biopsy
Fischer R, Baukloh V, Naether O, Schulze W, Salzbrunn A, Benson D
HUM REPROD. 1996;11(10):2197-9.

A new concept for the extraction of testicular spermatozoa as a tool for assisted fertilization (ICSI)
Salzbrunn A, Benson D, Holstein A, Schulze W
HUM REPROD. 1996;11(4):752-5.