Tanja Zeller
Prof. Dr. rer. nat.
Tanja Zeller
  • Professor for Genomics and Systems Biology, DZHK Professor


Campus Forschung N27 , Raumnummer 03 040
Deutsch (Muttersprache)



  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011

Noninvasive peripheral vascular function and atrial fibrillation in the general population
Börschel C, Rübsamen N, Ojeda F, Wild P, Hoffmann B, Prochaska J, Gori T, Lackner K, Blankenberg S, Zeller T, Münzel T, Schnabel R
J HYPERTENS. 2018 [Epub ahead of print].

Predictive value of long-term changes of growth differentiation factor-15 over a 27-year-period for heart failure and death due to coronary heart disease
Fluschnik N, Ojeda F, Zeller T, Jørgensen T, Kuulasmaa K, Becher P, Sinning C, Blankenberg S, Westermann D
PLOS ONE. 2018;13(5):e0197497.

Evaluation of microribonucleic acids as potential biomarkers in the bicuspid aortic valve-associated aortopathy
Girdauskas E, Petersen J, Neumann N, Groß T, Naito S, Hillebrand M, Reichenspurner H, Blankenberg S, Zeller T
INTERACT CARDIOV TH. 2018;27(1):60-66.

Novel Approaches for BAV Aortopathy Prediction-Is There a Need for Cohort Studies and Biomarkers?
Girdauskas E, Petersen J, Neumann N, Naito S, Gross T, Jagodzinski A, Reichenspurner H, Zeller T
Biomolecules. 2018;8(3):.

MiR-145 expression and rare NOTCH1 variants in bicuspid aortic valve-associated aortopathy
Girdauskas E, Petersen J, Neumann N, Ungelenk M, Kurth I, Reichenspurner H, Zeller T
PLOS ONE. 2018;13(7):e0200205.

Novel DNA Methylation Sites Influence GPR15 Expression in Relation to Smoking
Haase T, Müller C, Krause J, Röthemeier C, Stenzig J, Kunze S, Waldenberger M, Münzel T, Pfeiffer N, Wild P, Michal M, Marini F, Karakas M, Lackner K, Blankenberg S, Zeller T
Biomolecules. 2018;8(3):74.

Precursor proadrenomedullin influences cardiomyocyte survival and local inflammation related to myocardial infarction
Hinrichs S, Scherschel K, Krüger S, Neumann J, Schwarzl M, Yan I, Warnke S, Ojeda F, Zeller T, Karakas M, Keller T, Meyer C, Blankenberg S, Westermann D, Lindner D
P NATL ACAD SCI USA. 2018;115(37):E8727-E8736.

Linking the sympathetic nervous system to the inflammasome: towards new therapeutics for atherosclerotic cardiovascular disease
Karakas M, Haase T, Zeller T
EUR HEART J. 2018;39(1):70-72.

Rat atrial engineered heart tissue: a new in vitro model to study atrial biology
Krause J, Löser A, Lemoine M, Christ T, Scherschel K, Meyer C, Blankenberg S, Zeller T, Eschenhagen T, Stenzig J
BASIC RES CARDIOL. 2018;113(5):41.

Atrial Fibrillation Manifestations Risk Factors and Sex Differences in a Population-Based Cohort (From the Gutenberg Health Study)
Magnussen C, Ojeda F, Wild P, Sörensen N, Rostock T, Hoffmann B, Prochaska J, Lackner K, Beutel M, Blettner M, Pfeiffer N, Rzayeva N, Sinning C, Blankenberg S, Münzel T, Zeller T, Schnabel R
AM J CARDIOL. 2018;122(1):76-82.

Evaluation of a new ultra-sensitivity troponin I assay in patients with suspected myocardial infarction
Neumann J, Sörensen N, Rübsamen N, Ojeda F, Schock A, Seddighizadeh P, Zeller T, Westermann D, Blankenberg S
INT J CARDIOL. 2018 [Epub ahead of print].

Troponin and BNP are markers for subsequent non-ischaemic congestive heart failure: the Caerphilly Prospective Study (CaPS)
Patterson C, Blankenberg S, Ben-Shlomo Y, Heslop L, Bayer A, Lowe G, Zeller T, Gallacher J, Young I, Yarnell J
Open Heart. 2018;5(1):e000692.

Corrigendum to "Prognostic Impact of Interleukin-1 Receptor Antagonist in Patients with documented Coronary Artery Disease" [Int. J. Cardiol. 257 (2018) 24-29]
Schofer N, Ludwig S, Rübsamen N, Schnabel R, Lackner K, Ruprecht H, Bickel C, Landmesser U, Blankenberg S, Zeller T
INT J CARDIOL. 2018;261:239.

Prognostic impact of Interleukin-1 receptor antagonist in patients with documented coronary artery disease
Schofer N, Ludwig S, Rübsamen N, Schnabel R, Lackner K, Ruprecht H, Bickel C, Landmesser U, Blankenberg S, Zeller T
INT J CARDIOL. 2018;257:24-29.

D-dimer Predicts Long-Term Cause-Specific Mortality, Cardiovascular Events and Cancer in Stable Coronary Heart Disease Patients: The LIPID Study
Simes J, Robledo K, White H, Espinoza D, Stewart R, Sullivan D, Zeller T, Hague W, Nestel P, Glasziou P, Keech A, Elliott J, Blankenberg S, Tonkin A
CIRCULATION. 2018;138(7):712-723.

Relations of Sex to Diagnosis and Outcomes in Acute Coronary Syndrome
Sörensen N, Neumann J, Ojeda F, Schäfer S, Magnussen C, Keller T, Lackner K, Zeller T, Karakas M, Münzel T, Blankenberg S, Westermann D, Schnabel R
J AM HEART ASSOC. 2018;7(6):.

Adherence to Mediterranean diet, high-sensitive C-reactive protein, and severity of coronary artery disease: Contemporary data from the INTERCATH cohort
Waldeyer C, Brunner F, Brätz J, Rübsamen N, Zyriax B, Blaum C, Kroeger F, Kohsiack R, Schrage B, Sinning C, Becher P, Karakas M, Zeller T, Westermann D, Sydow K, Blankenberg S, Seiffert M, Schnabel R
ATHEROSCLEROSIS. 2018;275:256-261.

Genetic Susceptibility Contributing to Periodontal and Cardiovascular Disease
Aarabi G, Zeller T, Seedorf H, Reissmann D, Heydecke G, Schaefer A, Seedorf U
J DENT RES. 2017;96(6):610-617.

Relation between Arterial Stiffness and Markers of Inflammation and Hemostasis - Data from the Population-based Gutenberg Health Study
Arnold N, Gori T, Schnabel R, Schulz A, Prochaska J, Zeller T, Binder H, Pfeiffer N, Beutel M, Espinola-Klein C, Lackner K, Blankenberg S, Münzel T, Wild P
SCI REP. 2017;7(1):6346.

Standard and Novel Biomarkers
Blankenberg S, Zeller T
2017. Chronic Coronary Artery Disease. de Lemos J, Omland T (Hrsg.). 1. Aufl. Elsevier Health Sciences, 98-113.

The challenges of genetic risk scores for the prediction of coronary heart disease
Börnigen D, Karakas M, Zeller T
CLIN CHEM LAB MED. 2017;55(10):1450-1452.

Transcriptomics in Cardiovascular Medicine
Börnigen D, Zeller T
2017. Encyclopedia of Cardiovascular Research and Medicine. Sawyer D, Vasan R (Hrsg.). 1. Aufl. Elsevier, 558-571.

A genomic exploration identifies mechanisms that may explain adverse cardiovascular effects of COX-2 inhibitors
Brænne I, Willenborg C, Tragante V, Kessler T, Zeng L, Reiz B, Kleinecke M, von Ameln S, Willer C, Laakso M, Wild P, Zeller T, Wallentin L, Franks P, Salomaa V, Dehghan A, Meitinger T, Samani N, Asselbergs F, Erdmann J, Schunkert H
SCI REP. 2017;7(1):10252.

Relations of Metabolically Healthy and Unhealthy Obesity to Digital Vascular Function in Three Community-Based Cohorts: A Meta-Analysis
Brant L, Wang N, Ojeda F, LaValley M, Barreto S, Benjamin E, Mitchell G, Vasan R, Palmisano J, Münzel T, Blankenberg S, Wild P, Zeller T, Ribeiro A, Schnabel R, Hamburg N
J AM HEART ASSOC. 2017;6(3):.

Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility
Chintalapudi S, Maria D, Di Wang X, Bailey J, Hysi P, Wiggs J, Williams R, Jablonski M
NAT COMMUN. 2017;8(1):1755.

Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study
de Vries P, Sabater-Lleal M, Chasman D, Trompet S, Ahluwalia T, Teumer A, Kleber M, Chen M, Wang J, Attia J, Marioni R, Steri M, Weng L, Pool R, Grossmann V, Brody J, Venturini C, Tanaka T, Rose L, Oldmeadow C, Mazur J, Basu S, Frånberg M, Yang Q, Ligthart S, Hottenga J, Rumley A, Mulas A, de Craen A, Grotevendt A, Taylor K, Delgado G, Kifley A, Lopez L, Berentzen T, Mangino M, Bandinelli S, Morrison A, Hamsten A, Tofler G, de Maat M, Draisma H, Lowe G, Zoledziewska M, Sattar N, Lackner K, Völker U, McKnight B, Huang J, Holliday E, McEvoy M, Starr J, Hysi P, Hernandez D, Guan W, Rivadeneira F, McArdle W, Slagboom P, Zeller T, Psaty B, Uitterlinden A, de Geus E, Stott D, Binder H, Hofman A, Franco O, Rotter J, Ferrucci L, Spector T, Deary I, März W, Greinacher A, Wild P, Cucca F, Boomsma D, Watkins H, Tang W, Ridker P, Jukema J, Scott R, Mitchell P, Hansen T, O'Donnell C, Smith N, Strachan D, Dehghan A
PLOS ONE. 2017;12(1):e0167742.

Circulating Levels of Interleukin 1-Receptor Antagonist and Risk of Cardiovascular Disease: Meta-Analysis of Six Population-Based Cohorts
Herder C, de Las Heras Gala T, Carstensen-Kirberg M, Huth C, Zierer A, Wahl S, Sudduth-Klinger J, Kuulasmaa K, Peretz D, Ligthart S, Bongaerts B, Dehghan A, Ikram M, Jula A, Kee F, Pietilä A, Saarela O, Zeller T, Blankenberg S, Meisinger C, Peters A, Roden M, Salomaa V, Koenig W, Thorand B
ARTERIOSCL THROM VAS. 2017;37(6):1222-1227.

Association of Repeatedly Measured High-Sensitivity-Assayed Troponin I with Cardiovascular Disease Events in a General Population from the MORGAM/BiomarCaRE Study
Hughes M, Ojeda Echevarria F, Saarela O, Jørgensen T, Zeller T, Palosaari T, O'Doherty M, Borglykke A, Kuulasmaa K, Blankenberg S, Kee F
CLIN CHEM. 2017;63(1):334-342.

Cardiovascular Biomarkers in Hypertensive Patients with Medical Treatment-Results from the Randomized TEAMSTA Protect I Trial
Jagodzinski A, Neumann J, Ojeda F, Sörensen N, Wild P, Münzel T, Zeller T, Westermann D, Blankenberg S
CLIN CHEM. 2017;63(12):1877-1885.

Circulating microRNAs strongly predict cardiovascular death in patients with coronary artery disease-results from the large AtheroGene study
Karakas M, Schulte C, Appelbaum S, Ojeda Echevarria F, Lackner K, Münzel T, Schnabel R, Blankenberg S, Zeller T
EUR HEART J. 2017;38(7):516-523.

A Biomarker Ocular: Circulating MicroRNAs Toward Diagnostics for Acute Ischemic Stroke
Karakas M, Zeller T
CIRC RES. 2017;121(8):905-907.

Matrix metalloproteinase-8 and tissue inhibitor of matrix metalloproteinase-1 predict incident cardiovascular disease events and all-cause mortality in a population-based cohort
Kormi I, Nieminen M, Havulinna A, Zeller T, Blankenberg S, Tervahartiala T, Sorsa T, Salomaa V, Pussinen P
EUR J PREV CARDIOL. 2017;24(11):1136-1144.

Sex Differences and Similarities in Atrial Fibrillation Epidemiology, Risk Factors, and Mortality in Community Cohorts: Results From the BiomarCaRE Consortium (Biomarker for Cardiovascular Risk Assessment in Europe)
Magnussen C, Niiranen T, Ojeda F, Gianfagna F, Blankenberg S, Njølstad I, Vartiainen E, Sans S, Pasterkamp G, Hughes M, Costanzo S, Donati M, Jousilahti P, Linneberg A, Palosaari T, de Gaetano G, Bobak M, den Ruijter H, Mathiesen E, Jørgensen T, Söderberg S, Kuulasmaa K, Zeller T, Iacoviello L, Salomaa V, Schnabel R
CIRCULATION. 2017;136(17):1588-1597.

FEV1 and FVC predict all-cause mortality independent of cardiac function - Results from the population-based Gutenberg Health Study
Magnussen C, Ojeda F, Rzayeva N, Zeller T, Sinning C, Pfeiffer N, Beutel M, Blettner M, Lackner K, Blankenberg S, Münzel T, Rabe K, Wild P, Schnabel R
INT J CARDIOL. 2017;234:64-68.

Biomarker response and therapy prediction in renal denervation therapy - the role of MR-proadrenomedullin in a multicenter approach
Neumann J, Schwerg M, Dörr O, Mortensen K, Franzen K, Zeller T, Ojeda Echevarria F, Blankenberg S, Hamm C, Nef H, Stangl V, Möckel M, Sydow K
BIOMARKERS. 2017;22(3-4):225-231.

Immediate Rule-Out of Acute Myocardial Infarction Using Electrocardiogram and Baseline High-Sensitivity Troponin I
Neumann J, Sörensen N, Ojeda Echevarria F, Schwemer T, Lehmacher J, Gönner S, Jarsetz N, Keller T, Schaefer S, Renné T, Landmesser U, Clemmensen P, Makarova N, Schnabel R, Zeller T, Karakas M, Pickering J, Than M, Parsonage W, Greenslade J, Cullen L, Westermann D, Blankenberg S
CLIN CHEM. 2017;63(1):394-402.

Early diagnosis of acute myocardial infarction using high-sensitivity troponin I
Neumann J, Sörensen N, Ojeda F, Renné T, Schnabel R, Zeller T, Karakas M, Blankenberg S, Westermann D
PLOS ONE. 2017;12(3):e0174288.

Discrimination of patients with type 2 myocardial infarction
Neumann J, Sörensen N, Rübsamen N, Ojeda F, Renné T, Qaderi V, Teltrop E, Kramer S, Quantius L, Zeller T, Karakas M, Blankenberg S, Westermann D
EUR HEART J. 2017;38(47):3514-3520.

Mean Platelet Volume and Arterial Stiffness - Clinical Relationship and Common Genetic Variability
Panova-Noeva M, Arnold N, Hermanns M, Prochaska J, Schulz A, Spronk H, Binder H, Pfeiffer N, Beutel M, Blankenberg S, Zeller T, Lotz J, Münzel T, Lackner K, Ten Cate H, Wild P
SCI REP. 2017;7:40229.

Asymptomatic Cocaine Abuse - Myocardial Tissue Characterization Using Cardiac Biomarkers and Cardiovascular Magnetic Resonance Imaging
Radunski U, Fuger U, Bohnen S, Lund G, Stehning C, Zeller T, Tahir E, Avanesov M, Adam G, Blankenberg S, Reimer J, Muellerleile K
CIRC J. 2017;81(5):701-708.

Genome-Wide Association Study Implicates Atrial Natriuretic Peptide Rather Than B-Type Natriuretic Peptide in the Regulation of Blood Pressure in the General Population
Salo P, Havulinna A, Tukiainen T, Raitakari O, Lehtimäki T, Kähönen M, Kettunen J, Männikkö M, Eriksson J, Jula A, Blankenberg S, Zeller T, Salomaa V, Kristiansson K, Perola M
CIRC-CARDIOVASC GENE. 2017;10(6):UNSP e001713.

Plasma levels of hepatocyte growth factor and placental growth factor predict mortality in a general Population: a prospective cohort study
Santalahti K, Havulinna A, Maksimow M, Zeller T, Blankenberg S, Vehtari A, Joensuu H, Jalkanen S, Salomaa V, Salmi M
J INTERN MED. 2017;282(4):340-352.

Gender-specific diagnostic performance of a new high-sensitivity cardiac troponin I assay for detection of acute myocardial infarction
Schofer N, Brunner F, Schlüter M, Ojeda Echevarria F, Zeller T, Baldus S, Bickel C, Lackner K, Münzel T, Tzikas S, Genth-Zotz S, Warnholtz A, Post F, Keller T, Goldmann B, Blankenberg S
Eur Heart J Acute Cardiovasc Care. 2017;6(1):60-68.

microRNAs in cardiovascular disease - clinical application
Schulte C, Karakas M, Zeller T
CLIN CHEM LAB MED. 2017;55(5):687-704.

Biomarkers for characterization of heart failure - Distinction of heart failure with preserved and reduced ejection fraction
Sinning C, Kempf T, Schwarzl M, Lanfermann S, Ojeda Echevarria F, Schnabel R, Zengin-Sahm E, Wild P, Lackner K, Munzel T, Blankenberg S, Wollert K, Zeller T, Westermann D
INT J CARDIOL. 2017;227:272-277.

Midregional proadrenomedullin and growth differentiation factor-15 are not influenced by obesity in heart failure patients
Sinning C, Ojeda F, Wild P, Schnabel R, Schwarzl M, Ohdah S, Lackner K, Pfeiffer N, Michal M, Blettner M, Munzel T, Kempf T, Wollert K, Kuulasmaa K, Blankenberg S, Salomaa V, Westermann D, Zeller T
CLIN RES CARDIOL. 2017;106(6):401-410.

Challenging the 99th percentile: A lower troponin cutoff leads to low mortality of chest pain patients
Sörensen N, Neumann J, Ojeda Echevarria F, Schwemer T, Renné T, Schnabel R, Zeller T, Karakas M, Blankenberg S, Westermann D
INT J CARDIOL. 2017;232:289-293.

New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics
Springelkamp H, Iglesias A, Mishra A, Höhn R, Wojciechowski R, Khawaja A, Nag A, Wang Y, Wang J, Cuellar-Partida G, Gibson J, Bailey J, Vithana E, Gharahkhani P, Boutin T, Ramdas W, Zeller T, Luben R, Yonova-Doing E, Viswanathan A, Yazar S, Cree A, Haines J, Koh J, Souzeau E, Wilson J, Amin N, Müller C, Venturini C, Kearns L, Kang J, Tham Y, Zhou T, van Leeuwen E, Nickels S, Sanfilippo P, Liao J, van der Linde H, Zhao W, van Koolwijk L, Zheng L, Rivadeneira F, Baskaran M, van der Lee S, Perera S, de Jong P, Oostra B, Uitterlinden A, Fan Q, Hofman A, Tai E, Vingerling J, Sim X, Wolfs R, Teo Y, Lemij H, Khor C, Willemsen R, Lackner K, Aung T, Jansonius N, Montgomery G, Wild P, Young T, Burdon K, Hysi P, Pasquale L, Wong T, Klaver C, Hewitt A, Jonas J, Mitchell P, Lotery A, Foster P, Vitart V, Pfeiffer N, Craig J, Mackey D, Hammond C, Wiggs J, Cheng C, van Duijn C, MacGregor S
HUM MOL GENET. 2017;26(2):438-453.

High-sensitivity cardiac troponin I and NT-proBNP as predictors of incident dementia and Alzheimer's disease: the FINRISK Study
Tynkkynen J, Hernesniemi J, Laatikainen T, Havulinna A, Salo P, Blankenberg S, Zeller T, Salomaa V
Front Neurol. 2017;264(3):503-511.

GDF-15 predicts cardiovascular events in acute chest pain patients
Tzikas S, Palapies L, Bakogiannis C, Zeller T, Sinning C, Baldus S, Bickel C, Vassilikos V, Lackner K, Zeiher A, Münzel T, Blankenberg S, Keller T
PLOS ONE. 2017;12(8):e0182314.

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis
van Rooij F, Qayyum R, Smith A, Zhou Y, Trompet S, Tanaka T, Keller M, Chang L, Schmidt H, Yang M, Chen M, Hayes J, Johnson A, Yanek L, Müller C, Lange L, Floyd J, Ghanbari M, Zonderman A, Jukema J, Hofman A, van Duijn C, Desch K, Saba Y, Ozel A, Snively B, Wu J, Schmidt R, Fornage M, Klein R, Fox C, Matsuda K, Kamatani N, Wild P, Stott D, Ford I, Slagboom P, Yang J, Chu A, Lambert A, Uitterlinden A, Franco O, Hofer E, Ginsburg D, Hu B, Keating B, Schick U, Brody J, Li J, Chen Z, Zeller T, Guralnik J, Chasman D, Peters L, Kubo M, Becker D, Li J, Eiriksdottir G, Rotter J, Levy D, Grossmann V, Patel K, Chen C, Ridker P, Tang H, Launer L, Rice K, Li-Gao R, Ferrucci L, Evans M, Choudhuri A, Trompouki E, Abraham B, Yang S, Takahashi A, Kamatani Y, Kooperberg C, Harris T, Jee S, Coresh J, Tsai F, Longo D, Chen Y, Felix J, Yang Q, Psaty B, Boerwinkle E, Becker L, Mook-Kanamori D, Wilson J, Gudnason V, O'Donnell C, Dehghan A, Cupples L, Nalls M, Morris A, Okada Y, Reiner A, Zon L, Ganesh S
AM J HUM GENET. 2017;100(1):51-63.

Urinary neutrophil gelatinase-associated lipocalin and cystatin C compared to the estimated glomerular filtration rate to predict risk in patients with suspected acute myocardial infarction
von Jeinsen B, Kraus D, Palapies L, Tzikas S, Zeller T, Schauer A, Drechsler C, Bickel C, Baldus S, Lackner K, Münzel T, Blankenberg S, Zeiher A, Keller T
INT J CARDIOL. 2017;245:6-12.

Poor adherence to Mediterranean diet is independently associated with the severity of coronary artery disease-contemporary data from the INTERCATH study
Waldeyer C, Brunner F, Seiffert M, Kohsiack R, Waldeyer R, Schrage B, Sinning C, Karakas M, Westermann D, Blankenberg S, Zeller T, Sydow K, Schnabel R
ATHEROSCLEROSIS. 2017;263:e169.

Lipoprotein(a) and the risk of cardiovascular disease in the European Population: results from the BiomarCaRE consortium
Waldeyer C, Makarova N, Zeller T, Schnabel R, Brunner F, Jørgensen T, Linneberg A, Niiranen T, Salomaa V, Jousilahti P, Yarnell J, Ferrario M, Veronesi G, Brambilla P, Signorini S, Iacoviello L, Costanzo S, Giampaoli S, Palmieri L, Meisinger C, Thorand B, Kee F, Koenig W, Ojeda F, Kontto J, Landmesser U, Kuulasmaa K, Blankenberg S
EUR HEART J. 2017;38(32):2490-2498.

Lipid Management After First Diagnosis of Coronary Artery Disease: Contemporary Results From an Observational Cohort Study
Waldeyer C, Seiffert M, Staebe N, Braetz J, Kohsiack R, Ojeda F, Schofer N, Karakas M, Zeller T, Sinning C, Schrage B, Westermann D, Sydow K, Blankenberg S, Brunner F, Schnabel R
CLIN THER. 2017;39(11):2311-2320.e2.

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function
Wild P, Felix J, Schillert A, Teumer A, Chen M, Leening M, Völker U, Großmann V, Brody J, Irvin M, Shah S, Pramana S, Lieb W, Schmidt R, Stanton A, Malzahn D, Smith A, Sundström J, Minelli C, Ruggiero D, Lyytikäinen L, Tiller D, Smith J, Monnereau C, Di Tullio M, Musani S, Morrison A, Pers T, Morley M, Kleber M, Aragam J, Benjamin E, Bis J, Bisping E, Broeckel U, Cheng S, Deckers J, Del Greco M F, Edelmann F, Fornage M, Franke L, Friedrich N, Harris T, Hofer E, Hofman A, Huang J, Hughes A, Kähönen M, Investigators K, Kruppa J, Lackner K, Lannfelt L, Laskowski R, Launer L, Leosdottir M, Lin H, Lindgren C, Loley C, MacRae C, Mascalzoni D, Mayet J, Medenwald D, Morris A, Müller C, Müller-Nurasyid M, Nappo S, Nilsson P, Nuding S, Nutile T, Peters A, Pfeufer A, Pietzner D, Pramstaller P, Raitakari O, Rice K, Rivadeneira F, Rotter J, Ruohonen S, Sacco R, Samdarshi T, Schmidt H, Sharp A, Shields D, Sorice R, Sotoodehnia N, Stricker B, Surendran P, Thom S, Töglhofer A, Uitterlinden A, Wachter R, Völzke H, Ziegler A, Münzel T, März W, Cappola T, Hirschhorn J, Mitchell G, Smith N, Fox E, Dueker N, Jaddoe V, Melander O, Russ M, Lehtimäki T, Ciullo M, Hicks A, Lind L, Gudnason V, Pieske B, Barron A, Zweiker R, Schunkert H, Ingelsson E, Liu K, Arnett D, Psaty B, Blankenberg S, Larson M, Felix S, Franco O, Zeller T, Vasan R, Dörr M
J CLIN INVEST. 2017;127(5):1798-1812.

Transcriptome-Wide Analysis Identifies Novel Associations With Blood Pressure
Zeller T, Schurmann C, Müller C, Kwon S, Wild P, Teumer A, Herrington D, Schillert A, Iacoviello L, Kratzer A, Jagodzinski A, Karakas M, Ding J, Neumann J, Kuulasmaa K, Gieger C, Kacprowski T, Schnabel R, Roden M, Wahl S, Rotter J, Ojeda F, Carstensen-Kirberg M, Tregouet D, Dörr M, Meitinger T, Lackner K, Wolf P, Felix S, Landmesser U, Costanzo S, Ziegler A, Liu Y, Völker U, Palmas W, Prokisch H, Guo X, Herder C, Blankenberg S, Homuth G
HYPERTENSION. 2017;70(4):743-750.

Genome-Wide Association Analysis for Severity of Coronary Artery Disease Using the Gensini Scoring System
Zeller T, Seiffert M, Müller C, Scholz M, Schäffer A, Ojeda F, Drexel H, Mündlein A, Kleber M, März W, Sinning C, Brunner F, Waldeyer C, Keller T, Saely C, Sydow K, Thiery J, Teupser D, Blankenberg S, Schnabel R
Front Cardiovasc Med. 2017;4:57.

Reference intervals of plasma homoarginine from the German Gutenberg Health Study
Atzler D, Appelbaum S, Cordts K, Ojeda Echevarria F, Wild P, Münzel T, Blankenberg S, Böger R, Blettner M, Beutel M, Pfeiffer N, Zeller T, Lackner K, Schwedhelm E
CLIN CHEM LAB MED. 2016;54(7):1231-7.

Low Homoarginine Levels in the Prognosis of Patients With Acute Chest Pain
Atzler D, Baum C, Ojeda Echevarria F, Keller T, Cordts K, Schnabel R, Choe C, Lackner K, Münzel T, Böger R, Blankenberg S, Schwedhelm E, Zeller T
J AM HEART ASSOC. 2016;5(4):e002565.

ADMA and arginine derivatives in relation to non-invasive vascular function in the general population
Baum C, Johannsen S, Zeller T, Atzler D, Ojeda Echevarria F, Wild P, Sinning C, Lackner K, Gori T, Schwedhelm E, Böger R, Blankenberg S, Münzel T, Schnabel R
ATHEROSCLEROSIS. 2016;244:149-56.

Subclinical impairment of lung function is related to mild cardiac dysfunction and manifest heart failure in the general population
Baum C, Ojeda Echevarria F, Wild P, Rzayeva N, Zeller T, Sinning C, Pfeiffer N, Beutel M, Blettner M, Lackner K, Blankenberg S, Münzel T, Rabe K, Schnabel R
INT J CARDIOL. 2016;218:298-304.

Predictors of leptin concentration and association with cardiovascular risk in patients with coronary artery disease: results from the AtheroGene study
Bickel C, Schnabel R, Zeller T, Lackner K, Rupprecht H, Blankenberg S, Sinning C, Westermann D
BIOMARKERS. 2016;22(3-4):210-218.

Troponin I and cardiovascular risk prediction in the general Population: the BiomarCaRE consortium
Blankenberg S, Salomaa V, Makarova N, Ojeda Echevarria F, Wild P, Lackner K, Jørgensen T, Thorand B, Peters A, Nauck M, Petersmann A, Vartiainen E, Veronesi G, Brambilla P, Costanzo S, Iacoviello L, Linden G, Yarnell J, Patterson C, Everett B, Ridker P, Kontto J, Schnabel R, Koenig W, Kee F, Zeller T, Kuulasmaa K
EUR HEART J. 2016;37(30):2428-37.

Cardiovascular biomarkers in paired maternal and umbilical cord blood samples at term and near term delivery
Blohm M, Arndt F, Sandig J, Diehl W, Zeller T, Müller G, Schlesner C, Mir T, Blankenberg S, Hecher K, Singer D, Weil J
Early human development. 2016;94:7-12.

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration
de Vries P, Chasman D, Sabater-Lleal M, Chen M, Huffman J, Steri M, Tang W, Teumer A, Marioni R, Grossmann V, Hottenga J, Trompet S, Müller-Nurasyid M, Zhao J, Brody J, Kleber M, Guo X, Wang J, Auer P, Attia J, Yanek L, Ahluwalia T, Lahti J, Venturini C, Tanaka T, Bielak L, Joshi P, Rocanin-Arjo A, Kolcic I, Navarro P, Rose L, Oldmeadow C, Riess H, Mazur J, Basu S, Goel A, Yang Q, Ghanbari M, Willemsen G, Rumley A, Fiorillo E, de Craen A, Grotevendt A, Scott R, Taylor K, Delgado G, Yao J, Kifley A, Kooperberg C, Qayyum R, Lopez L, Berentzen T, Räikkönen K, Mangino M, Bandinelli S, Peyser P, Wild S, Trégouët D, Wright A, Marten J, Zemunik T, Morrison A, Sennblad B, Tofler G, de Maat M, de Geus E, Lowe G, Zoledziewska M, Sattar N, Binder H, Völker U, Waldenberger M, Khaw K, Mcknight B, Huang J, Jenny N, Holliday E, Qi L, Mcevoy M, Becker D, Starr J, Sarin A, Hysi P, Hernandez D, Jhun M, Campbell H, Hamsten A, Rivadeneira F, Mcardle W, Slagboom P, Zeller T, Koenig W, Psaty B, Haritunians T, Liu J, Palotie A, Uitterlinden A, Stott D, Hofman A, Franco O, Polasek O, Rudan I, Morange P, Wilson J, Kardia S, Ferrucci L, Spector T, Eriksson J, Hansen T, Deary I, Becker L, Scott R, Mitchell P, März W, Wareham N, Peters A, Greinacher A, Wild P, Jukema J, Boomsma D, Hayward C, Cucca F, Tracy R, Watkins H, Reiner A, Folsom A, Ridker P, O'Donnell C, Smith N, Strachan D, Dehghan A
HUM MOL GENET. 2016;25(2):358-70.

Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error
Fan Q, Verhoeven V, Wojciechowski R, Barathi V, Hysi P, Guggenheim J, Höhn R, Vitart V, Khawaja A, Yamashiro K, Hosseini S, Lehtimäki T, Lu Y, Haller T, Xie J, Delcourt C, Pirastu M, Wedenoja J, Gharahkhani P, Venturini C, Miyake M, Hewitt A, Guo X, Mazur J, Huffman J, Williams K, Polasek O, Campbell H, Rudan I, Vatavuk Z, Wilson J, Joshi P, McMahon G, St Pourcain B, Evans D, Simpson C, Schwantes-An T, Igo R, Mirshahi A, Cougnard-Gregoire A, Bellenguez C, Blettner M, Raitakari O, Kähönen M, Seppala I, Zeller T, Meitinger T, Ried J, Gieger C, Portas L, van Leeuwen E, Amin N, Uitterlinden A, Rivadeneira F, Hofman A, Vingerling J, Wang Y, Wang X, Tai-Hui Boh E, Ikram M, Sabanayagam C, Gupta P, Tan V, Zhou L, Ho C, Lim W, Beuerman R, Siantar R, Tai E, Vithana E, Mihailov E, Khor C, Hayward C, Luben R, Foster P, Klein B, Klein R, Wong H, Mitchell P, Metspalu A, Aung T, Young T, He M, Pärssinen O, van Duijn C, Jin Wang J, Williams C, Jonas J, Teo Y, Mackey D, Oexle K, Yoshimura N, Paterson A, Pfeiffer N, Wong T, Baird P, Stambolian D, Wilson J, Cheng Y, Hammond C, Klaver C, Saw S, Rahi J, Korobelnik J, Kemp J, Timpson N, Smith G, Craig J, Burdon K, Fogarty R, Iyengar S, Chew E, Janmahasatian S, Martin N, Macgregor S, Xu L, Schache M, Nangia V, Panda-Jonas S, Wright A, Fondran J, Lass J, Feng S, Zhao J, Khaw K, Wareham N, Rantanen T, Kaprio J, Pang C, Chen L, Tam P, Jhanji V, Young A, Döring A, Raffel L, Cotch M, Li X, Yip S, Yap M, Biino G, Vaccargiu S, Fossarello M, Fleck B, Yazar S, Tideman J, Tedja M, Deangelis M, Morrison M, Farrer L, Zhou X, Chen W, Mizuki N, Meguro A, Mäkelä K
NAT COMMUN. 2016;7:11008.

Endophenotype Network Models: Common Core of Complex Diseases
Ghiassian S, Menche J, Chasman D, Giulianini F, Wang R, Ricchiuto P, Aikawa M, Iwata H, Müller C, Zeller T, Sharma A, Wild P, Lackner K, Singh S, Ridker P, Blankenberg S, Barabási A, Loscalzo J
SCI REP. 2016;6:27414.

Systems Medicine as an Emerging Tool for Cardiovascular Genetics
Haase T, Börnigen D, Müller C, Zeller T
Front Cardiovasc Med. 2016;3:27.

The Predictive Value of Depressive Symptoms for All-Cause Mortality: Findings From the PRIME Belfast Study Examining the Role of Inflammation and Cardiovascular Risk Markers
Hughes M, Patterson C, Appleton K, Blankenberg S, Woodside J, Donnelly M, Linden G, Zeller T, Esquirol Y, Kee F
PSYCHOSOM MED. 2016;78(4):401-11.

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA
Kettunen J, Demirkan A, Würtz P, Draisma H, Haller T, Rawal R, Vaarhorst A, Kangas A, Lyytikäinen L, Pirinen M, Pool R, Sarin A, Soininen P, Tukiainen T, Wang Q, Tiainen M, Tynkkynen T, Amin N, Zeller T, Beekman M, Deelen J, van Dijk K, Esko T, Hottenga J, van Leeuwen E, Lehtimäki T, Mihailov E, Rose R, de Craen A, Gieger C, Kähönen M, Perola M, Blankenberg S, Savolainen M, Verhoeven A, Viikari J, Willemsen G, Boomsma D, van Duijn C, Eriksson J, Jula A, Järvelin M, Kaprio J, Metspalu A, Raitakari O, Salomaa V, Slagboom P, Waldenberger M, Ripatti S, Ala-Korpela M
NAT COMMUN. 2016;7:11122.

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels
Kilpeläinen T, Carli J, Skowronski A, Sun Q, Kriebel J, Feitosa M, Hedman Å, Drong A, Hayes J, Zhao J, Pers T, Schick U, Grarup N, Kutalik Z, Trompet S, Mangino M, Kristiansson K, Beekman M, Lyytikäinen L, Eriksson J, Henneman P, Lahti J, Tanaka T, Luan J, Greco M F, Pasko D, Renström F, Willems S, Mahajan A, Rose L, Guo X, Liu Y, Kleber M, Pérusse L, Gaunt T, Ahluwalia T, Ju Sung Y, Ramos Y, Amin N, Amuzu A, Barroso I, Bellis C, Blangero J, Buckley B, Böhringer S, I Chen Y, de Craen A, Crosslin D, Dale C, Dastani Z, Day F, Deelen J, Delgado G, Demirkan A, Finucane F, Ford I, Garcia M, Gieger C, Gustafsson S, Hallmans G, Hankinson S, Havulinna A, Herder C, Hernandez D, Hicks A, Hunter D, Illig T, Ingelsson E, Ioan-Facsinay A, Jansson J, Jenny N, Jørgensen M, Jørgensen T, Karlsson M, Koenig W, Kraft P, Kwekkeboom J, Laatikainen T, Ladwig K, LeDuc C, Lowe G, Lu Y, Marques-Vidal P, Meisinger C, Menni C, Morris A, Myers R, Männistö S, Nalls M, Paternoster L, Peters A, Pradhan A, Rankinen T, Rasmussen-Torvik L, Rathmann W, Rice T, Brent Richards J, Ridker P, Sattar N, Savage D, Söderberg S, Timpson N, Vandenput L, van Heemst D, Uh H, Vohl M, Walker M, Wichmann H, Widén E, Wood A, Yao J, Zeller T, Zhang Y, Meulenbelt I, Kloppenburg M, Astrup A, Sørensen T, Sarzynski M, Rao D, Jousilahti P, Vartiainen E, Hofman A, Rivadeneira F, Uitterlinden A, Kajantie E, Osmond C, Palotie A, Eriksson J, Heliövaara M, Knekt P, Koskinen S, Jula A, Perola M, Huupponen R, Viikari J, Kähönen M, Lehtimäki T, Raitakari O, Mellström D, Lorentzon M, Casas J, Bandinelli S, März W, Isaacs A, van Dijk K, van Duijn C, Harris T, Bouchard C, Allison M, Chasman D, Ohlsson C, Lind L, Scott R, Langenberg C, Wareham N, Ferrucci L, Frayling T, Pramstaller P, Borecki I, Waterworth D, Bergmann S, Waeber G, Vollenweider P, Vestergaard H, Hansen T, Pedersen O, Hu F, Eline Slagboom P, Grallert H, Spector T, Jukema J, Klein R, Schadt E, Franks P, Lindgren C, Leibel R, Loos R
NAT COMMUN. 2016;7:10494.

Development of nonfibrotic left ventricular hypertrophy in an ANG II-induced chronic ovine hypertension model
Klatt N, Scherschel K, Schad C, Lau D, Reitmeier A, Kuklik P, Müllerleile K, Yamamura J, Zeller T, Steven D, Baldus S, Schäffer B, Jungen C, Eickholt C, Wassilew K, Schwedhelm E, Willems S, Meyer C
Physiological reports. 2016;4(17):.

Early detection of myocardial infarction-microRNAs right at the time?
Kränkel N, Blankenberg S, Zeller T
Ann Transl Med. 2016;4(24):502.

Antiphospholipid antibodies in a large population-based cohort: genome-wide associations and effects on monocyte gene expression
Müller-Calleja N, Rossmann H, Müller C, Wild P, Blankenberg S, Pfeiffer N, Binder H, Beutel M, Manukyan D, Zeller T, Lackner K
J THROMB HAEMOST. 2016;116(1):115-23.

Removing Batch Effects from Longitudinal Gene Expression - Quantile Normalization Plus ComBat as Best Approach for Microarray Transcriptome Data
Müller C, Schillert A, Röthemeier C, Trégouët D, Proust C, Binder H, Pfeiffer N, Beutel M, Lackner K, Schnabel R, Tiret L, Wild P, Blankenberg S, Zeller T, Ziegler A
PLOS ONE. 2016;11(6):e0156594.

Effects of renal denervation on heart failure biomarkers and blood pressure in patients with resistant hypertension
Neumann J, Ewen S, Mortensen K, Nef H, Zeller T, Ojeda Echevarria F, Sydow K, Mahfoud F, Böhm M, Hamm C, Dörr O, Blankenberg S
Biomarker Med. 2016;10(8):841-51.

Diagnosis of Myocardial Infarction Using a High-Sensitivity Troponin I 1-Hour Algorithm
Neumann J, Sörensen N, Schwemer T, Ojeda Echevarria F, Bourry R, Sciacca V, Schäfer S, Waldeyer C, Sinning C, Renné T, Than M, Parsonage W, Wildi K, Makarova N, Schnabel R, Landmesser U, Mueller C, Cullen L, Greenslade J, Zeller T, Blankenberg S, Karakas M, Westermann D
JAMA Cardiol. 2016;1(4):397-404.

Comparison of Cox Model Methods in A Low-dimensional Setting with Few Events
Ojeda Echevarria F, Müller C, Börnigen D, Trégouët D, Schillert A, Heinig M, Zeller T, Schnabel R
Genomics Proteom Bioinform. 2016;14(4):235-43.

PO-58 - Cardiovascular risk profile in survivors of adult cancer - results from the general population study
Panova-Noeva M, Hermanns M, Schulz A, Laubert-Reh D, Zeller T, Blankenberg S, Spronk H, Münzel T, Lackner K, Ten Cate H, Wild P

Sex-specific differences in genetic and nongenetic determinants of mean platelet volume: results from the Gutenberg Health Study
Panova-Noeva M, Schulz A, Hermanns M, Grossmann V, Pefani E, Spronk H, Laubert-Reh D, Binder H, Beutel M, Pfeiffer N, Blankenberg S, Zeller T, Münzel T, Lackner K, Ten Cate H, Wild P
BLOOD. 2016;127(2):251-9.

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function
Pattaro C, Teumer A, Gorski M, Chu A, Li M, Mijatovic V, Garnaas M, Tin A, Sorice R, Li Y, Taliun D, Olden M, Foster M, Yang Q, Chen M, Pers T, Johnson A, Ko Y, Fuchsberger C, Tayo B, Nalls M, Feitosa M, Isaacs A, Dehghan A, D'Adamo P, Adeyemo A, Dieffenbach A, Zonderman A, Nolte I, van der Most P, Wright A, Shuldiner A, Morrison A, Hofman A, Smith A, Dreisbach A, Franke A, Uitterlinden A, Metspalu A, Tonjes A, Lupo A, Robino A, Johansson Å, Demirkan A, Kollerits B, Freedman B, Ponte B, Oostra B, Paulweber B, Krämer B, Mitchell B, Buckley B, Peralta C, Hayward C, Helmer C, Rotimi C, Shaffer C, Müller C, Sala C, van Duijn C, Saint-Pierre A, Ackermann D, Shriner D, Ruggiero D, Toniolo D, Lu Y, Cusi D, Czamara D, Ellinghaus D, Siscovick D, Ruderfer D, Gieger C, Grallert H, Rochtchina E, Atkinson E, Holliday E, Boerwinkle E, Salvi E, Bottinger E, Murgia F, Rivadeneira F, Ernst F, Kronenberg F, Hu F, Navis G, Curhan G, Ehret G, Homuth G, Coassin S, Thun G, Pistis G, Gambaro G, Malerba G, Montgomery G, Eiriksdottir G, Jacobs G, Li G, Wichmann H, Campbell H, Schmidt H, Wallaschofski H, Völzke H, Brenner H, Kroemer H, Kramer H, Lin H, Leach I, Ford I, Guessous I, Rudan I, Prokopenko I, Borecki I, Heid I, Kolcic I, Persico I, Jukema J, Wilson J, Felix J, Divers J, Lambert J, Stafford J, Gaspoz J, Smith J, Faul J, Wang J, Ding J, Hirschhorn J, Attia J, Whitfield J, Chalmers J, Viikari J, Coresh J, Denny J, Karjalainen J, Fernandes J, Endlich K, Butterbach K, Keene K, Lohman K, Portas L, Launer L, Lyytikäinen L, Yengo L, Franke L, Ferrucci L, Rose L, Kedenko L, Rao M, Struchalin M, Kleber M, Cavalieri M, Haun M, Cornelis M, Ciullo M, Pirastu M, de Andrade M, McEvoy M, Woodward M, Adam M, Cocca M, Nauck M, Imboden M, Waldenberger M, Pruijm M, Metzger M, Stumvoll M, Evans M, Sale M, Kähönen M, Boban M, Bochud M, Rheinberger M, Verweij N, Bouatia-Naji N, Martin N, Hastie N, Probst-Hensch N, Soranzo N, Devuyst O, Raitakari O, Gottesman O, Franco O, Polasek O, Gasparini P, Munroe P, Ridker P, Mitchell P, Muntner P, Meisinger C, Smit J, Kovacs P, Wild P, Froguel P, Rettig R, Mägi R, Biffar R, Schmidt R, Middelberg R, Carroll R, Penninx B, Scott R, Katz R, Sedaghat S, Wild S, Kardia S, Ulivi S, Hwang S, Enroth S, Kloiber S, Trompet S, Stengel B, Hancock S, Turner S, Rosas S, Stracke S, Harris T, Zeller T, Zemunik T, Lehtimäki T, Illig T, Aspelund T, Nikopensius T, Esko T, Tanaka T, Gyllensten U, Völker U, Emilsson V, Vitart V, Aalto V, Gudnason V, Chouraki V, Chen M, Igl W, März W, Koenig W, Lieb W, Loos R, Liu Y, Snieder H, Pramstaller P, Parsa A, O'Connell J, Susztak K, Hamet P, Tremblay J, de Boer I, Böger C, Goessling W, Chasman D, Köttgen A, Kao W, Fox C
NAT COMMUN. 2016;7:10023.

Systematically evaluating interfaces for RNA-seq analysis from a life scientist perspective
Poplawski A, Marini F, Hess M, Zeller T, Mazur J, Binder H
Brief Bioinform. 2016;17(2):213-23.

ADMA, subclinical changes and atrial fibrillation in the general population
Ramuschkat M, Appelbaum S, Atzler D, Zeller T, Bauer C, Ojeda Echevarria F, Sinning C, Hoffmann B, Lackner K, Böger R, Wild P, Münzel T, Blankenberg S, Schwedhelm E, Schnabel R
INT J CARDIOL. 2016;203:640-6.

Risk factors for heart failure are associated with alterations of the LV end-diastolic pressure-volume relationship in non-heart failure individuals: data from a large-scale, population-based cohort
Schwarzl M, Ojeda Echevarria F, Zeller T, Seiffert M, Becher P, Munzel T, Wild P, Blettner M, Lackner K, Pfeiffer N, Beutel M, Blankenberg S, Westermann D
EUR HEART J. 2016;37(23):1807-14.

Cardiovascular Mortality in Chest Pain Patients: Comparison of Natriuretic Peptides With Novel Biomarkers of Cardiovascular Stress
Sinning C, Ojeda Echevarria F, Zeller T, Zengin-Sahm E, Rupprecht H, Lackner K, Bickel C, Blankenberg S, Schnabel R, Westermann D
AM J CARDIOL. 2016;32(12):1470-1477.

Prognostic use of soluble fms-like tyrosine kinase-1 and placental growth factor in patients with coronary artery disease
Sinning C, Schnabel R, Zeller T, Seiffert M, Rupprecht H, Lackner K, Blankenberg S, Bickel C, Westermann D
Biomarker Med. 2016;10(1):95-106.

SYNTAX score-0 patients: risk stratification in nonobstructive coronary artery disease
Sinning C, Zengin-Sahm E, Waldeyer C, Seiffert M, Schnabel R, Lubos E, Zeller T, Bickel C, Blankenberg S, Clemmensen P, Westermann D
CLIN RES CARDIOL. 2016;105(11):901-911.

High-sensitivity troponin and novel biomarkers for the early diagnosis of non-ST-segment elevation myocardial infarction in patients with atrial fibrillation
Sörensen N, Shah A, Ojeda Echevarria F, Peitsmeyer P, Zeller T, Keller T, Johannsen S, Lackner K, Griffiths M, Münzel T, Mills N, Blankenberg S, Schnabel R
Eur Heart J Acute Cardiovasc Care. 2016;5(6):419-427.

Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes
Teumer A, Tin A, Sorice R, Gorski M, Yeo N, Chu A, Li M, Li Y, Mijatovic V, Ko Y, Taliun D, Luciani A, Chen M, Yang Q, Foster M, Olden M, Hiraki L, Tayo B, Fuchsberger C, Dieffenbach A, Shuldiner A, Smith A, Zappa A, Lupo A, Kollerits B, Ponte B, Stengel B, Krämer B, Paulweber B, Mitchell B, Hayward C, Helmer C, Meisinger C, Gieger C, Shaffer C, Müller C, Langenberg C, Ackermann D, Siscovick D, Boerwinkle E, Kronenberg F, Ehret G, Homuth G, Waeber G, Navis G, Gambaro G, Malerba G, Eiriksdottir G, Li G, Wichmann H, Grallert H, Wallaschofski H, Völzke H, Brenner H, Kramer H, Mateo Leach I, Rudan I, Hillege H, Beckmann J, Lambert J, Luan J, Zhao J, Chalmers J, Coresh J, Denny J, Butterbach K, Launer L, Ferrucci L, Kedenko L, Haun M, Metzger M, Woodward M, Hoffman M, Nauck M, Waldenberger M, Pruijm M, Bochud M, Rheinberger M, Verweij N, Wareham N, Endlich N, Soranzo N, Polasek O, van der Harst P, Pramstaller P, Vollenweider P, Wild P, Gansevoort R, Rettig R, Biffar R, Carroll R, Katz R, Loos R, Hwang S, Coassin S, Bergmann S, Rosas S, Stracke S, Harris T, Corre T, Zeller T, Illig T, Aspelund T, Tanaka T, Lendeckel U, Völker U, Gudnason V, Chouraki V, Koenig W, Kutalik Z, O'Connell J, Parsa A, Heid I, Paterson A, de Boer I, Devuyst O, Lazar J, Endlich K, Susztak K, Tremblay J, Hamet P, Jacob H, Böger C, Fox C, Pattaro C, Köttgen A
DIABETES. 2016;65(3):803-17.

When do myopia genes have their effect? Comparison of genetic risks between children and adults
Tideman J, Fan Q, Polling J, Guo X, Yazar S, Khawaja A, Höhn R, Lu Y, Jaddoe V, Yamashiro K, Yoshikawa M, Gerhold-Ay A, Nickels S, Zeller T, He M, Boutin T, Bencic G, Vitart V, Mackey D, Foster P, Macgregor S, Williams C, Saw S, Guggenheim J, Klaver C
Genetic epidemiology. 2016;40(8):756-766.

Characterization of the metabolic profile associated with serum 25-hydroxyvitamin D: a cross-sectional analysis in population-based data
Vogt S, Wahl S, Kettunen J, Breitner S, Kastenmüller G, Gieger C, Suhre K, Waldenberger M, Kratzsch J, Perola M, Salomaa V, Blankenberg S, Zeller T, Soininen P, Kangas A, Peters A, Grallert H, Ala-Korpela M, Thorand B
INT J EPIDEMIOL. 2016;45(5):1469-1481.

Troponin I Assay for Identification of a Significant Coronary Stenosis in Patients with Suspected Acute Myocardial Infarction and Wide QRS Complex
von Jeinsen B, Tzikas S, Pioro G, Palapies L, Zeller T, Bickel C, Lackner K, Baldus S, Blankenberg S, Muenzel T, Zeiher A, Keller T
PLOS ONE. 2016;11(5):e0154724.

The predictive value of different equations for estimation of glomerular filtration rate in patients with coronary artery disease - Results from the AtheroGene study
Waldeyer C, Karakas M, Scheurle C, Ojeda Echevarria F, Schnabel R, Zeller T, Zengin-Sahm E, Westermann D, Schrage B, Bickel C, Rupprecht H, Lackner K, Blankenberg S, Seiffert M, Sinning C
INT J CARDIOL. 2016;221:908-13.

Metabolic profiling of pregnancy: cross-sectional and longitudinal evidence
Wang Q, Würtz P, Auro K, Mäkinen V, Kangas A, Soininen P, Tiainen M, Tynkkynen T, Jokelainen J, Santalahti K, Salmi M, Blankenberg S, Zeller T, Viikari J, Kähönen M, Lehtimäki T, Salomaa V, Perola M, Jalkanen S, Järvelin M, Raitakari O, Kettunen J, Lawlor D, Ala-Korpela M
BMC MED . 2016;14(1):205.

Effects of hormonal contraception on systemic metabolism: cross-sectional and longitudinal evidence
Wang Q, Würtz P, Auro K, Morin-Papunen L, Kangas A, Soininen P, Tiainen M, Tynkkynen T, Joensuu A, Havulinna A, Aalto K, Salmi M, Blankenberg S, Zeller T, Viikari J, Kähönen M, Lehtimäki T, Salomaa V, Jalkanen S, Järvelin M, Perola M, Raitakari O, Lawlor D, Kettunen J, Ala-Korpela M
INT J EPIDEMIOL. 2016;45(5):1445-1457.

Metabolic profiling of alcohol consumption in 9778 young adults
Würtz P, Cook S, Wang Q, Tiainen M, Tynkkynen T, Kangas A, Soininen P, Laitinen J, Viikari J, Kähönen M, Lehtimäki T, Perola M, Blankenberg S, Zeller T, Männistö S, Salomaa V, Järvelin M, Raitakari O, Ala-Korpela M, Leon D
INT J EPIDEMIOL. 2016;45(5):1493-1506.

Lung function in relation to cardiac dysfunction and heart failure in the general population
Baum C, Ojeda Echevarria F, Wild P, Rzayeva N, Zeller T, Sinning C, Blankenberg S, Münzel T, Rabe K, Schnabel R
EUR HEART J. 2015;36(Suppl. 1):727-727.

Estimation of Values below the Limit of Detection of a Contemporary Sensitive Troponin I Assay Improves Diagnosis of Acute Myocardial Infarction
Boeckel J, Palapies L, Zeller T, Reis S, von Jeinsen B, Tzikas S, Bickel C, Baldus S, Blankenberg S, Münzel T, Zeiher A, Lackner K, Keller T
CLIN CHEM. 2015;61(9):1197-206.

Alterations of a Cellular Cholesterol Metabolism Network Are a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease
Ding J, Reynolds L, Zeller T, Müller C, Lohman K, Nicklas B, Kritchevsky S, Huang Z, de la Fuente A, Soranzo N, Settlage R, Chuang C, Howard T, Xu N, Goodarzi M, Chen Y, Rotter J, Siscovick D, Parks J, Murphy S, Jacobs D, Post W, Tracy R, Wild P, Blankenberg S, Hoeschele I, Herrington D, McCall C, Liu Y
DIABETES. 2015;64(10):3464-74.

High-sensitivity cardiac troponin I and B-type natriuretic Peptide as predictors of vascular events in primary prevention: impact of statin therapy
Everett B, Zeller T, Glynn R, Ridker P, Blankenberg S
CIRCULATION. 2015;131(21):1851-60.

Underrepresentation of sex in reporting traditional and emerging biomarkers for primary prevention of cardiovascular disease: A systematic review
Gohar A, Schnabel R, Hughes M, Zeller T, Blankenberg S, Pasterkamp G, Ruijter H
Eur Heart J-Qual Care Clin Outcome. 2015 [Epub ahead of print].

Profile of the Immune and Inflammatory Response in Individuals With Prediabetes and Type 2 Diabetes
Grossmann V, Schmitt V, Zeller T, Panova-Noeva M, Schulz A, Laubert-Reh D, Juenger C, Schnabel R, Abt T, Laskowski R, Wiltink J, Schulz E, Blankenberg S, Lackner K, Münzel T, Wild P
DIABETES CARE. 2015;38(7):1356-64.

Inflammatory bowel disease (IBD) locus 12: is glutathione peroxidase-1 (GPX1) the relevant gene?
Häuser F, Rossmann H, Laubert-Reh D, Wild P, Zeller T, Müller C, Neuwirth S, Blankenberg S, Lackner K
GENES IMMUN. 2015;16(8):571-5.

Distribution, genetic and cardiovascular determinants of FVIII:c - Data from the population-based Gutenberg Health Study
Hermanns M, Grossmann V, Spronk H, Schulz A, Jünger C, Laubert-Reh D, Mazur J, Gori T, Zeller T, Pfeiffer N, Beutel M, Blankenberg S, Münzel T, Lackner K, Ten Cate-Hoek A, Ten Cate H, Wild P
INT J CARDIOL. 2015;187:166-74.

Extensive alterations of the whole-blood transcriptome are associated with body mass index: results of an mRNA profiling study involving two large population-based cohorts
Homuth G, Wahl S, Müller C, Schurmann C, Mäder U, Blankenberg S, Carstensen M, Dörr M, Endlich K, Englbrecht C, Felix S, Gieger C, Grallert H, Herder C, Illig T, Kruppa J, Marzi C, Mayerle J, Meitinger T, Metspalu A, Nauck M, Peters A, Rathmann W, Reinmaa E, Rettig R, Roden M, Schillert A, Schramm K, Steil L, Strauch K, Teumer A, Völzke H, Wallaschofski H, Wild P, Ziegler A, Völker U, Prokisch H, Zeller T
GENOMICS. 2015;8:65.

A meta-analysis of gene expression signatures of blood pressure and hypertension
Huan T, Esko T, Peters M, Pilling L, Schramm K, Schurmann C, Chen B, Liu C, Joehanes R, Johnson A, Yao C, Ying S, Courchesne P, Milani L, Raghavachari N, Wang R, Liu P, Reinmaa E, Dehghan A, Hofman A, Uitterlinden A, Hernandez D, Bandinelli S, Singleton A, Melzer D, Metspalu A, Carstensen M, Grallert H, Herder C, Meitinger T, Peters A, Roden M, Waldenberger M, Dörr M, Felix S, Zeller T, Vasan R, O'Donnell C, Munson P, Yang X, Prokisch H, Völker U, van Meurs J, Ferrucci L, Levy D
PLOS GENET. 2015;11(3):e1005035.

Predictive value of galectin-3 for incident cardiovascular disease and heart failure in the population-based FINRISK 1997 cohort
Jagodzinski A, Havulinna A, Appelbaum S, Zeller T, Jousilahti P, Johannsen S, Hughes M, Blankenberg S, Salomaa V
INT J CARDIOL. 2015;192:33-9.

Genome-wide association study identifies new susceptibility loci for cutaneous lupus erythematosus
Kunz M, König I, Schillert A, Kruppa J, Ziegler A, Grallert H, Müller-Nurasyid M, Lieb W, Franke A, Ranki A, Panelius J, Koskenmies S, Hasan T, Kere J, Rönn A, Simon J, Schmidt E, Wenzel J, Tüting T, Landsberg J, Zeller T, Blankenberg S, Gläser R, Patsinakidis N, Kuhn A, Ibrahim S
EXP DERMATOL. 2015;24(7):510-5.

Identification of acute myocardial infarction in patients with atrial fibrillation and chest pain with a contemporary sensitive troponin I assay
Liebetrau C, Weber M, Tzikas S, Palapies L, Möllmann H, Pioro G, Zeller T, Beiras-Fernandez A, Bickel C, Zeiher A, Lackner K, Baldus S, Nef H, Blankenberg S, Hamm C, Münzel T, Keller T
BMC MED . 2015;13:169.

Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium
Li Q, Wojciechowski R, Simpson C, Hysi P, Verhoeven V, Ikram M, Höhn R, Vitart V, Hewitt A, Oexle K, Mäkelä K, MacGregor S, Pirastu M, Fan Q, Cheng C, St Pourcain B, McMahon G, Kemp J, Northstone K, Rahi J, Cumberland P, Martin N, Sanfilippo P, Lu Y, Wang Y, Hayward C, Polašek O, Campbell H, Bencic G, Wright A, Wedenoja J, Zeller T, Schillert A, Mirshahi A, Lackner K, Yip S, Yap M, Ried J, Gieger C, Murgia F, Wilson J, Fleck B, Yazar S, Vingerling J, Hofman A, Uitterlinden A, Rivadeneira F, Amin N, Karssen L, Oostra B, Zhou X, Teo Y, Tai E, Vithana E, Barathi V, Zheng Y, Siantar R, Neelam K, Shin Y, Lam J, Yonova-Doing E, Venturini C, Hosseini S, Wong H, Lehtimäki T, Kähönen M, Raitakari O, Timpson N, Evans D, Khor C, Aung T, Young T, Mitchell P, Klein B, van Duijn C, Meitinger T, Jonas J, Baird P, Mackey D, Wong T, Saw S, Pärssinen O, Stambolian D, Hammond C, Klaver C, Williams C, Paterson A, Bailey-Wilson J, Guggenheim J
HUM GENET. 2015;134(2):131-46.

Protein biomarkers for the prediction of cardiovascular disease in type 2 diabetes
Looker H, Colombo M, Agakov F, Zeller T, Groop L, Thorand B, Palmer C, Hamsten A, de Faire U, Nogoceke E, Livingstone S, Salomaa V, Leander K, Barbarini N, Bellazzi R, van Zuydam N, McKeigue P, Colhoun H
Diabetologia. 2015;58(6):1363-71.

Reversal of Mitochondrial Transhydrogenase Causes Oxidative Stress in Heart Failure
Nickel A, von Hardenberg A, Hohl M, Löffler J, Kohlhaas M, Becker J, Reil J, Kazakov A, Bonnekoh J, Stadelmaier M, Puhl S, Wagner M, Bogeski I, Cortassa S, Kappl R, Pasieka B, Lafontaine M, Lancaster C, Blacker T, Hall A, Duchen M, Kästner L, Lipp P, Zeller T, Müller C, Knopp A, Laufs U, Böhm M, Hoth M, Maack C
CELL METAB. 2015;22(3):472-84.

Which biomarkers are predictive specifically for cardiovascular or for non-cardiovascular mortality in men? Evidence from the Caerphilly Prospective Study (CaPS)
Patterson C, Blankenberg S, Ben-Shlomo Y, Heslop L, Bayer A, Lowe G, Zeller T, Gallacher J, Young I, Yarnell J
INT J CARDIOL. 2015;201:113-8.

Sex Differences in Correlates of Intermediate Phenotypes and Prevalent Cardiovascular Disease in the General Population
Schnabel R, Wild P, Prochaska J, Ojeda Echevarria F, Zeller T, Rzayeva N, Ebrahim A, Lackner K, Beutel M, Pfeiffer N, Sinning C, Oertelt-Prigione S, Regitz-Zagrosek V, Binder H, Münzel T, Blankenberg S
Front Cardiovasc Med. 2015;2:15.

miRNA-197 and miRNA-223 Predict Cardiovascular Death in a Cohort of Patients with Symptomatic Coronary Artery Disease
Schulte C, Molz S, Appelbaum S, Karakas M, Ojeda Echevarria F, Lau D, Hartmann T, Lackner K, Westermann D, Schnabel R, Blankenberg S, Zeller T
PLOS ONE. 2015;10(12):e0145930.

Diagnostic and prognostic value of circulating microRNAs in heart failure with preserved and reduced ejection fraction
Schulte C, Westermann D, Blankenberg S, Zeller T
World J Cardiol. 2015;7(12):843-60.

microRNA-based diagnostics and therapy in cardiovascular disease-Summing up the facts
Schulte C, Zeller T
Cardiovasc Diagn Ther. 2015;5(1):17-36.

Candidate biomarkers in heart failure with reduced and preserved ejection fraction
Sinning C, Zengin E, Zeller T, Schnabel R, Blankenberg S, Westermann D
BIOMARKERS. 2015;20(4):258-65.

Biomarkers in stable coronary heart disease, their modulation and cardiovascular risk: The LIPID biomarker study
Tonkin A, Blankenberg S, Kirby A, Zeller T, Colquhoun D, Funke-Kaiser A, Hague W, Hunt D, Keech A, Nestel P, Stewart R, Sullivan D, Thompson P, West M, White H, Simes J
INT J CARDIOL. 2015;201:499-507.

NT-proBNP and the Risk of Dementia: A Prospective Cohort Study with 14 Years of Follow-Up
Tynkkynen J, Laatikainen T, Salomaa V, Havulinna A, Blankenberg S, Zeller T, Hernesniemi J
J ALZHEIMERS DIS. 2015;44(3):1007-13.

SASH1, a new potential link between smoking and atherosclerosis
Weidmann H, Touat-Hamici Z, Durand H, Müller C, Chardonnet S, Pionneau C, Charlotte F, Janssen K, Verdugo R, Cambien F, Blankenberg S, Tiret L, Zeller T, Ninio E
ATHEROSCLEROSIS. 2015;242(2):571-9.

Heme oxygenase-1 suppresses a pro-inflammatory phenotype in monocytes and determines endothelial function and arterial hypertension in mice and humans
Wenzel P, Rossmann H, Müller C, Kossmann S, Oelze M, Schulz A, Arnold N, Simsek C, Lagrange J, Klemz R, Schönfelder T, Brandt M, Karbach S, Knorr M, Finger S, Neukirch C, Häuser F, Beutel M, Kröller-Schön S, Schulz E, Schnabel R, Lackner K, Wild P, Zeller T, Daiber A, Blankenberg S, Münzel T
EUR HEART J. 2015;36(48):3437-46.

Molecular Characterization of the NLRC4 Expression in Relation to Interleukin-18 Levels
Zeller T, Haase T, Müller C, Riess H, Lau D, Zeller S, Krause J, Baumert J, Pless O, Dupuis J, Wild P, Eleftheriadis M, Waldenberger M, Zeilinger S, Ziegler A, Peters A, Tiret L, Proust C, Marzi C, Munzel T, Strauch K, Prokisch H, Lackner K, Herder C, Thorand B, Benjamin E, Blankenberg S, Koenig W, Schnabel R
CIRC-CARDIOVASC GENE. 2015;8(5):717-26.

High-sensitivity cardiac troponin I in the general population--defining reference populations for the determination of the 99th percentile in the Gutenberg Health Study
Zeller T, Ojeda Echevarria F, Brunner F, Peitsmeyer P, Münzel T, Binder H, Pfeiffer N, Michal M, Wild P, Blankenberg S, Lackner K
CLIN CHEM LAB MED. 2015;53(5):699-706.

Risk Factors of Coronary Artery Disease in Secondary Prevention--Results from the AtheroGene--Study
Zengin E, Bickel C, Schnabel R, Zeller T, Lackner K, Rupprecht H, Blankenberg S, Westermann D, Sinning C
PLOS ONE. 2015;10(7):e0131434.

Activity of superoxide dismutase copper/zinc type and prognosis in a cohort of patients with coronary artery disease
Zengin E, Sinning C, Zeller T, Rupprecht H, Schnabel R, Lackner K, Blankenberg S, Westermann D, Bickel C
Biomarker Med. 2015;9(6):597-604.

The utility of pregnancy-associated plasma protein A for determination of prognosis in a cohort of patients with coronary artery disease
Zengin E, Sinning C, Zeller T, Rupprecht H, Schnabel R, Lackner K, Blankenberg S, Westermann D, Bickel C
Biomarker Med. 2015;9(8):731-41.

Adrenomedullin and arterial stiffness: integrative approach combining monocyte ADM expression, plasma MR-Pro-ADM, and genome-wide association study
Beygui F, Wild P, Zeller T, Germain M, Castagné R, Lackner K, Münzel T, Montalescot G, Mitchell G, Verwoert G, Tarasov K, Trégouët D, Cambien F, Blankenberg S, Tiret L
CIRC-CARDIOVASC GENE. 2014;7(5):634-41.

Dichloroacetate prevents restenosis in preclinical animal models of vessel injury
Deuse T, Hua X, Wang D, Maegdefessel L, Heeren J, Scheja L, Bolaños J, Rakovic A, Spin J, Stubbendorff M, Ikeno F, Länger F, Zeller T, Schulte-Uentrop L, Stoehr A, Itagaki R, Haddad F, Eschenhagen T, Blankenberg S, Kiefmann R, Reichenspurner H, Velden J, Klein C, Yeung A, Robbins R, Tsao P, Schrepfer S
NATURE. 2014;509(7502):641-4.

The contribution of educational class in improving accuracy of cardiovascular risk prediction across European regions: The MORGAM Project Cohort Component
Ferrario M, Veronesi G, Chambless L, Tunstall-Pedoe H, Kuulasmaa K, Salomaa V, Borglykke A, Hart N, Söderberg S, Cesana G
HEART. 2014;100(15):1179-87.

Predictive value of midregional pro-adrenomedullin compared to natriuretic peptides for incident cardiovascular disease and heart failure in the population-based FINRISK 1997 cohort
Funke-Kaiser A, Havulinna A, Zeller T, Appelbaum S, Jousilahti P, Vartiainen E, Blankenberg S, Sydow K, Salomaa V
ANN INTERN MED. 2014;46(3):155-62.

Midregional proadrenomedullin and its change predicts recurrent major coronary events and heart failure in stable coronary heart disease patients: the LIPID study
Funke-Kaiser A, Mann K, Colquhoun D, Zeller T, Hunt D, Simes J, Sullivan D, Sydow K, West M, White H, Blankenberg S, Tonkin A
INT J CARDIOL. 2014;172(2):411-8.

Genetic determinants of circulating interleukin-1 receptor antagonist levels and their association with glycemic traits
Herder C, Nuotio M, Shah S, Blankenberg S, Brunner E, Carstensen M, Gieger C, Grallert H, Jula A, Kähönen M, Kettunen J, Kivimäki M, Koenig W, Kristiansson K, Langenberg C, Lehtimäki T, Luotola K, Marzi C, Müller C, Peters A, Prokisch H, Raitakari O, Rathmann W, Roden M, Salmi M, Schramm K, Swerdlow D, Tabak A, Thorand B, Wareham N, Wild P, Zeller T, Hingorani A, Witte D, Kumari M, Perola M, Salomaa V
DIABETES. 2014;63(12):4343-59.

Total serum transforming growth factor-β1 is elevated in the entire spectrum of genetic aortic syndromes
Hillebrand M, Millot N, Sheikhzadeh S, Rybczynski M, Gerth S, Kölbel T, Keyser B, Kutsche K, Robinson P, Berger J, Mir T, Zeller T, Blankenberg S, von Kodolitsch Y, Goldmann B
CLIN CARDIOL. 2014;37(11):672-9.

Novel genetic approach to investigate the role of plasma secretory phospholipase A2 (sPLA2)-V isoenzyme in coronary heart disease: modified Mendelian randomization analysis using PLA2G5 expression levels
Holmes M, Exeter H, Folkersen L, Nelson C, Guardiola M, Cooper J, Sofat R, Boekholdt S, Khaw K, Li K, Smith A, Van't Hooft F, Eriksson P, Franco-Cereceda A, Asselbergs F, Boer J, Onland-Moret N, Hofker M, Erdmann J, Kivimaki M, Kumari M, Reiner A, Keating B, Humphries S, Hingorani A, Mallat Z, Samani N, Talmud P
CIRC-CARDIOVASC GENE. 2014;7(2):144-50.

ST2 may not be a useful predictor for incident cardiovascular events, heart failure and mortality
Hughes M, Appelbaum S, Havulinna A, Jagodzinski A, Zeller T, Kee F, Blankenberg S, Salomaa V
HEART. 2014;100(21):1715-21.

Distribution and medical impact of loss-of-function variants in the Finnish founder population
Lim E, Würtz P, Havulinna A, Palta P, Tukiainen T, Rehnström K, Esko T, Mägi R, Inouye M, Lappalainen T, Chan Y, Salem R, Lek M, Flannick J, Sim X, Manning A, Ladenvall C, Bumpstead S, Hämäläinen E, Aalto K, Maksimow M, Salmi M, Blankenberg S, Ardissino D, Shah S, Horne B, McPherson R, Hovingh G, Reilly M, Watkins H, Goel A, Farrall M, Girelli D, Reiner A, Stitziel N, Kathiresan S, Gabriel S, Barrett J, Lehtimäki T, Laakso M, Groop L, Kaprio J, Perola M, McCarthy M, Boehnke M, Altshuler D, Lindgren C, Hirschhorn J, Metspalu A, Freimer N, Zeller T, Jalkanen S, Koskinen S, Raitakari O, Durbin R, MacArthur D, Salomaa V, Ripatti S, Daly M, Palotie A
PLOS GENET. 2014;10(7):e1004494.

Myopia and level of education: results from the Gutenberg Health Study
Mirshahi A, Ponto K, Hoehn R, Zwiener I, Zeller T, Lackner K, Beutel M, Pfeiffer N
OPHTHALMOLOGY. 2014;121(10):2047-52.

Comparison of three troponins as predictors of future cardiovascular events--prospective results from the FINRISK and BiomaCaRE studies
Neumann J, Havulinna A, Zeller T, Appelbaum S, Kunnas T, Nikkari S, Jousilahti P, Blankenberg S, Sydow K, Salomaa V
PLOS ONE. 2014;9(3):e90063.

A meta-analysis of genome-wide association studies identifies ORM1 as a novel gene controlling thrombin generation potential
Rocanin-Arjo A, Cohen W, Carcaillon L, Frère C, Saut N, Letenneur L, Alhenc-Gelas M, Dupuy A, Bertrand M, Alessi M, Germain M, Wild P, Zeller T, Cambien F, Goodall A, Amouyel P, Scarabin P, Trégouët D, Morange P
BLOOD. 2014;123(5):777-85.

Multiple biomarkers and atrial fibrillation in the general population
Schnabel R, Wild P, Wilde S, Ojeda Echevarria F, Schulz A, Zeller T, Sinning C, Kunde J, Lackner K, Munzel T, Blankenberg S
PLOS ONE. 2014;9(11):e112486.

Biomarkers of coronary artery disease: the promise of the transcriptome
Siemelink M, Zeller T
Curr Cardiol Rep. 2014;16(8):513.

Association of high-sensitivity assayed troponin I with cardiovascular phenotypes in the general Population: the population-based Gutenberg health study
Sinning C, Keller T, Zeller T, Ojeda Echevarria F, Schlüter M, Schnabel R, Lubos E, Bickel C, Lackner K, Diemert P, Munzel T, Blankenberg S, Wild P
CLIN RES CARDIOL. 2014;103(3):211-22.

Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change
Würtz P, Wang Q, Kangas A, Richmond R, Skarp J, Tiainen M, Tynkkynen T, Soininen P, Havulinna A, Kaakinen M, Viikari J, Savolainen M, Kähönen M, Lehtimäki T, Männistö S, Blankenberg S, Zeller T, Laitinen J, Pouta A, Mäntyselkä P, Vanhala M, Elliott P, Pietiläinen K, Ripatti S, Salomaa V, Raitakari O, Järvelin M, Smith G, Ala-Korpela M
PLOS MED. 2014;11(12):e1001765.

BiomarCaRE: rationale and design of the European BiomarCaRE project including 300,000 participants from 13 European countries
Zeller T, Hughes M, Tuovinen T, Schillert A, Conrads-Frank A, Ruijter H, Schnabel R, Kee F, Salomaa V, Siebert U, Thorand B, Ziegler A, Breek H, Pasterkamp G, Kuulasmaa K, Koenig W, Blankenberg S
EUR J EPIDEMIOL. 2014;29(10):777-90.

Assessment of microRNAs in patients with unstable angina pectoris
Zeller T, Keller T, Ojeda Echevarria F, Reichlin T, Twerenbold R, Tzikas S, Wild P, Reiter M, Czyz E, Lackner K, Munzel T, Mueller C, Blankenberg S
EUR HEART J. 2014.

High population prevalence of cardiac troponin I measured by a high-sensitivity assay and cardiovascular risk estimation: the MORGAM Biomarker Project Scottish Cohort
Zeller T, Tunstall-Pedoe H, Saarela O, Ojeda Echevarria F, Schnabel R, Tuovinen T, Woodward M, Struthers A, Hughes M, Kee F, Salomaa V, Kuulasmaa K, Blankenberg S
EUR HEART J. 2014;35(5):271-81.

GUESS-ing polygenic associations with multiple phenotypes using a GPU-based evolutionary stochastic search algorithm
Bottolo L, Chadeau-Hyam M, Hastie D, Zeller T, Liquet B, Newcombe P, Yengo L, Wild P, Schillert A, Ziegler A, Nielsen S, Butterworth A, Ho W, Castagné R, Munzel T, Tregouet D, Falchi M, Cambien F, Nordestgaard B, Fumeron F, Tybjærg-Hansen A, Froguel P, Danesh J, Petretto E, Blankenberg S, Tiret L, Richardson S
PLOS GENET. 2013;9(8):e1003657.

Dysfunctional nitric oxide signalling increases risk of myocardial infarction
Erdmann J, Stark K, Esslinger U, Rumpf P, Koesling D, de Wit C, Kaiser F, Braunholz D, Medack A, Fischer M, Zimmermann M, Tennstedt S, Graf E, Eck S, Aherrahrou Z, Nahrstaedt J, Willenborg C, Bruse P, Brænne I, Nöthen M, Hofmann P, Braund P, Mergia E, Reinhard W, Burgdorf C, Schreiber S, Balmforth A, Hall A, Bertram L, Steinhagen-Thiessen E, Li S, März W, Reilly M, Kathiresan S, McPherson R, Walter U, Ott J, Samani N, Strom T, Meitinger T, Hengstenberg C, Schunkert H
NATURE. 2013;504(7480):432-6.

Genome-wide haplotype analysis of cis expression quantitative trait loci in monocytes
Garnier S, Truong V, Brocheton J, Zeller T, Rovital M, Wild P, Ziegler A, Munzel T, Tiret L, Blankenberg S, Deloukas P, Erdmann J, Hengstenberg C, Samani N, Schunkert H, Ouwehand W, Goodall A, Cambien F, Trégouët D
PLOS GENET. 2013;9(1):e1003240.

Defining a reference population to determine the 99th percentile of a contemporary sensitive cardiac troponin I assay.
Keller T, Ojeda Echevarria F, Zeller T, Wild P, Tzikas S, Sinning C, Peetz D, Münzel T, Blankenberg S, Lackner K
INT J CARDIOL. 2013;167(4):1423-1429.

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations
Köttgen A, Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, Pistis G, Ruggiero D, O'Seaghdha C, Haller T, Yang Q, Tanaka T, Johnson A, Kutalik Z, Smith A, Shi J, Struchalin M, Middelberg R, Brown M, Gaffo A, Pirastu N, Li G, Hayward C, Zemunik T, Huffman J, Yengo L, Zhao J, Demirkan A, Feitosa M, Liu X, Malerba G, Lopez L, van der Harst P, Li X, Kleber M, Hicks A, Nolte I, Johansson A, Murgia F, Wild S, Bakker S, Peden J, Dehghan A, Steri M, Tenesa A, Lagou V, Salo P, Mangino M, Rose L, Lehtimäki T, Woodward O, Okada Y, Tin A, Müller C, Oldmeadow C, Putku M, Czamara D, Kraft P, Frogheri L, Thun G, Grotevendt A, Gislason G, Harris T, Launer L, McArdle P, Shuldiner A, Boerwinkle E, Coresh J, Schmidt H, Schallert M, Martin N, Montgomery G, Kubo M, Nakamura Y, Tanaka T, Munroe P, Samani N, Jacobs D, Liu K, D'Adamo P, Ulivi S, Rotter J, Psaty B, Vollenweider P, Waeber G, Campbell S, Devuyst O, Navarro P, Kolcic I, Hastie N, Balkau B, Froguel P, Esko T, Salumets A, Khaw K, Langenberg C, Wareham N, Isaacs A, Kraja A, Zhang Q, Wild P, Scott R, Holliday E, Org E, Viigimaa M, Bandinelli S, Metter J, Lupo A, Trabetti E, Sorice R, Döring A, Lattka E, Strauch K, Theis F, Waldenberger M, Wichmann H, Davies G, Gow A, Bruinenberg M, Stolk R, Kooner J, Zhang W, Winkelmann B, Boehm B, Lucae S, Penninx B, Smit J, Curhan G, Mudgal P, Plenge R, Portas L, Persico I, Kirin M, Wilson J, Mateo Leach I, van Gilst W, Goel A, Ongen H, Hofman A, Rivadeneira F, Uitterlinden A, Imboden M, von Eckardstein A, Cucca F, Nagaraja R, Piras M, Nauck M, Schurmann C, Budde K, Ernst F, Farrington S, Theodoratou E, Prokopenko I, Stumvoll M, Jula A, Perola M, Salomaa V, Shin S, Spector T, Sala C, Ridker P, Kähönen M, Viikari J, Hengstenberg C, Nelson C, Meschia J, Nalls M, Sharma P, Singleton A, Kamatani N, Zeller T, Burnier M, Attia J, Laan M, Klopp N, Hillege H, Kloiber S, Choi H, Pirastu M, Tore S, Probst-Hensch N, Völzke H, Gudnason V, Parsa A, Schmidt R, Whitfield J, Fornage M, Gasparini P, Siscovick D, Polašek O, Campbell H, Rudan I, Bouatia-Naji N, Metspalu A, Loos R, van Duijn C, Borecki I, Ferrucci L, Gambaro G, Deary I, Wolffenbuttel B, Chambers J, März W, Pramstaller P, Snieder H, Gyllensten U, Wright A, Navis G, Watkins H, Witteman J, Sanna S, Schipf S, Dunlop M, Tönjes A, Ripatti S, Soranzo N, Toniolo D, Chasman D, Raitakari O, Kao W, Ciullo M, Fox C, Caulfield M, Bochud M, Gieger C
NAT GENET. 2013;45(2):145-54.

Genetic predisposition to higher blood pressure increases coronary artery disease risk
Lieb W, Jansen H, Loley C, Pencina M, Nelson C, Newton-Cheh C, Kathiresan S, Reilly M, Assimes T, Boerwinkle E, Hall A, Hengstenberg C, Laaksonen R, McPherson R, Thorsteinsdottir U, Ziegler A, Peters A, Thompson J, König I, Erdmann J, Samani N, Vasan R, Schunkert H, Assimes T, Deloukas P, Erdmann J, Holm H, Kathiresan S, König I, McPherson R, Reilly M, Roberts R, Samani N, Schunkert H, Stewart A
HYPERTENSION. 2013;61(5):995-1001.

Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus
Lu Y, Vitart V, Burdon K, Khor C, Bykhovskaya Y, Mirshahi A, Hewitt A, Koehn D, Hysi P, Ramdas W, Zeller T, Vithana E, Cornes B, Tay W, Tai E, Cheng C, Liu J, Foo J, Saw S, Thorleifsson G, Stefansson K, Dimasi D, Mills R, Mountain J, Ang W, Hoehn R, Verhoeven V, Grus F, Wolfs R, Castagne R, Lackner K, Springelkamp H, Yang J, Jonasson F, Leung D, Chen L, Tham C, Rudan I, Vatavuk Z, Hayward C, Gibson J, Cree A, MacLeod A, Ennis S, Polasek O, Campbell H, Wilson J, Viswanathan A, Fleck B, Li X, Siscovick D, Taylor K, Rotter J, Yazar S, Ulmer M, Li J, Yaspan B, Ozel A, Richards J, Moroi S, Haines J, Kang J, Pasquale L, Allingham R, Ashley-Koch A, Mitchell P, Wang J, Wright A, Pennell C, Spector T, Young T, Klaver C, Martin N, Montgomery G, Anderson M, Aung T, Willoughby C, Wiggs J, Pang C, Thorsteinsdottir U, Lotery A, Hammond C, van Duijn C, Hauser M, Rabinowitz Y, Pfeiffer N, Mackey D, Craig J, Macgregor S, Wong T
NAT GENET. 2013;45(2):155-63.

The validity of heart failure diagnoses obtained from administrative registers
Mähönen M, Jula A, Harald K, Antikainen R, Tuomilehto J, Zeller T, Blankenberg S, Salomaa V
EUR J PREV CARDIOL. 2013;20(2):254-9.

Differential associations of depressive symptom dimensions with cardio-vascular disease in the community: results from the Gutenberg health study
Michal M, Wiltink J, Kirschner Y, Wild P, Ojeda Echevarria F, Münzel T, Zeller T, Schnabel R, Lackner K, Blettner M, Zwiener I, Beutel M
PLOS ONE. 2013;8(8):e72014.

Association of MR-proadrenomedullin with cardiovascular risk factors and subclinical cardiovascular disease
Neumann J, Tzikas S, Funke-Kaiser A, Wilde S, Appelbaum S, Keller T, Ojeda Echevarria F, Zeller T, Zwiener I, Sinning C, Jagodzinski A, Schnabel R, Lackner K, Münzel T, Blankenberg S, Wild P, Sydow K
ATHEROSCLEROSIS. 2013;228(2):451-9.

Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia
Reiner A, Hartiala J, Zeller T, Bis J, Dupuis J, Fornage M, Baumert J, Kleber M, Wild P, Baldus S, Bielinski S, Fontes J, Illig T, Keating B, Lange L, Ojeda Echevarria F, Müller-Nurasyid M, Munzel T, Psaty B, Rice K, Rotter J, Schnabel R, Tang W, Thorand B, Erdmann J, , Jacobs D, Wilson J, Koenig W, Tracy R, Blankenberg S, März W, Gross M, Benjamin E, Hazen S, Allayee H
HUM MOL GENET. 2013;22(16):3381-93.

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease
Sabater-Lleal M, Huang J, Chasman D, Naitza S, Dehghan A, Johnson A, Teumer A, Reiner A, Folkersen L, Basu S, Rudnicka A, Trompet S, Mälarstig A, Baumert J, Bis J, Guo X, Hottenga J, Shin S, Lopez L, Lahti J, Tanaka T, Yanek L, Oudot-Mellakh T, Wilson J, Navarro P, Huffman J, Zemunik T, Redline S, Mehra R, Pulanic D, Rudan I, Wright A, Kolcic I, Polasek O, Wild S, Campbell H, Curb J, Wallace R, Liu S, Eaton C, Becker D, Becker L, Bandinelli S, Räikkönen K, Widen E, Palotie A, Fornage M, Green D, Gross M, Davies G, Harris S, Liewald D, Starr J, Williams F, Grant P, Spector T, Strawbridge R, Silveira A, Sennblad B, Rivadeneira F, Uitterlinden A, Franco O, Hofman A, van Dongen J, Willemsen G, Boomsma D, Yao J, Swords Jenny N, Haritunians T, McKnight B, Lumley T, Taylor K, Rotter J, Psaty B, Peters A, Gieger C, Illig T, Grotevendt A, Homuth G, Völzke H, Kocher T, Goel A, Franzosi M, Seedorf U, Clarke R, Steri M, Tarasov K, Sanna S, Schlessinger D, Stott D, Sattar N, Buckley B, Rumley A, Lowe G, McArdle W, Chen M, Tofler G, Song J, Boerwinkle E, Folsom A, Rose L, Franco-Cereceda A, Teichert M, Ikram M, Mosley T, Bevan S, Dichgans M, Rothwell P, Sudlow C, Hopewell J, Chambers J, Saleheen D, Kooner J, Danesh J, Nelson C, Erdmann J, Reilly M, Kathiresan S, Schunkert H, Morange P, Ferrucci L, Eriksson J, Jacobs D, Deary I, Soranzo N, Witteman J, de Geus E, Tracy R, Hayward C, Koenig W, Cucca F, Jukema J, Eriksson P, Seshadri S, Markus H, Watkins H, Samani N, Wallaschofski H, Smith N, Tregouet D, Ridker P, Tang W, Strachan D, Hamsten A, O'Donnell C
CIRCULATION. 2013;128(12):1310-24.

Sex differences in noninvasive vascular function in the community
Schnabel R, Biener M, Wilde S, Sinning C, Ojeda Echevarria F, Zeller T, Lubos E, Lackner K, Warnholtz A, Gori T, Espinola-Klein C, Blankenberg S, Munzel T, Wild P
J HYPERTENS. 2013;31(7):1437-46; discussion 1446.

Depression in atrial fibrillation in the general population
Schnabel R, Michal M, Wilde S, Wiltink J, Wild P, Sinning C, Lubos E, Ojeda Echevarria F, Zeller T, Munzel T, Blankenberg S, Beutel M
PLOS ONE. 2013;8(12):e79109.

Association between multiple biomarkers and classical risk factors with early carotid atherosclerosis
Sinning C, Kieback A, Wild P, Appelbaum S, Schnabel R, Zeller T, Debus E, Münzel T, Blankenberg S, Espinola-Klein C
EUR HEART J. 2013;34(Suppl. 1):463-463.

Angiographic score assessment improves cardiovascular risk prediction: the clinical value of SYNTAX and Gensini application
Sinning C, Lillpopp L, Appelbaum S, Ojeda Echevarria F, Zeller T, Schnabel R, Lubos E, Jagodzinski A, Keller T, Munzel T, Bickel C, Blankenberg S
CLIN RES CARDIOL. 2013;102(7):495-503.

Adaptive linear rank tests for eQTL studies
Szymczak S, Scheinhardt M, Zeller T, Wild P, Blankenberg S, Ziegler A
STAT MED. 2013;32(3):524-537.

Fine-mapping, gene expression and splicing analysis of the disease associated LRRK2 locus
Trabzuni D, Ryten M, Emmett W, Ramasamy A, Lackner K, Zeller T, Walker R, Smith C, Lewis P, Mamais A, de Silva R, Vandrovcova J, Hernandez D, Nalls M, Sharma M, Garnier S, Lesage S, Simon-Sanchez J, Gasser T, Heutink P, Brice A, Singleton A, Cai H, Schadt E, Wood N, Bandopadhyay R, Weale M, Hardy J, Plagnol V
PLOS ONE. 2013;8(8):e70724.

MR-proANP and MR-proADM for risk stratification of patients with acute chest pain
Tzikas S, Keller T, Ojeda Echevarria F, Zeller T, Wild P, Lubos E, Kunde J, Baldus S, Bickel C, Lackner K, Münzel T, Blankenberg S
HEART. 2013;99(6):388-95.

Midregional pro-atrial natriuretic peptide in the general population/Insights from the Gutenberg Health Study
Tzikas S, Keller T, Wild P, Schulz A, Zwiener I, Zeller T, Schnabel R, Sinning C, Lubos E, Kunde J, Münzel T, Lackner K, Blankenberg S
CLIN CHEM LAB MED. 2013;51(5):1125-33.

Graphical modeling of gene expression in monocytes suggests molecular mechanisms explaining increased atherosclerosis in smokers
Verdugo R, Zeller T, Rotival M, Wild P, Münzel T, Lackner K, Weidmann H, Ninio E, Trégouët D, Cambien F, Blankenberg S, Tiret L
PLOS ONE. 2013;8(1):e50888.

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia
Verhoeven V, Hysi P, Wojciechowski R, Fan Q, Guggenheim J, Höhn R, MacGregor S, Hewitt A, Nag A, Cheng C, Yonova-Doing E, Zhou X, Ikram M, Buitendijk G, McMahon G, Kemp J, Pourcain B, Simpson C, Mäkelä K, Lehtimäki T, Kähönen M, Paterson A, Hosseini S, Wong H, Xu L, Jonas J, Pärssinen O, Wedenoja J, Yip S, Ho D, Pang C, Chen L, Burdon K, Craig J, Klein B, Klein R, Haller T, Metspalu A, Khor C, Tai E, Aung T, Vithana E, Tay W, Barathi V, Chen P, Li R, Liao J, Zheng Y, Ong R, Döring A, Evans D, Timpson N, Verkerk A, Meitinger T, Raitakari O, Hawthorne F, Spector T, Karssen L, Pirastu M, Murgia F, Ang W, Mishra A, Montgomery G, Pennell C, Cumberland P, Cotlarciuc I, Mitchell P, Wang J, Schache M, Janmahasatian S, Janmahasathian S, Igo R, Lass J, Chew E, Iyengar S, Gorgels T, Rudan I, Hayward C, Wright A, Polasek O, Vatavuk Z, Wilson J, Fleck B, Zeller T, Mirshahi A, Müller C, Uitterlinden A, Rivadeneira F, Vingerling J, Hofman A, Oostra B, Amin N, Bergen A, Teo Y, Rahi J, Vitart V, Williams C, Baird P, Wong T, Oexle K, Pfeiffer N, Mackey D, Young T, van Duijn C, Saw S, Bailey-Wilson J, Stambolian D, Klaver C, Hammond C
NAT GENET. 2013;45(3):314-8.

Changes in lipoprotein-Associated phospholipase A2 activity predict coronary events and partly account for the treatment effect of pravastatin: results from the Long-Term Intervention with Pravastatin in Ischemic Disease study
White H, Simes J, Stewart R, Blankenberg S, Barnes E, Marschner I, Thompson P, West M, Zeller T, Colquhoun D, Nestel P, Keech A, Sullivan D, Hunt D, Tonkin A
J AM HEART ASSOC. 2013;2(5):e000360.

Blood-based gene expression tests: promises and limitations
Zeller T, Blankenberg S
CIRC-CARDIOVASC GENE. 2013;6(2):139-40.

Type D personality as a cardiovascular risk marker in the general population: results from the Gutenberg health study.
Beutel M, Wiltink J, Till Y, Wild P, Münzel T, Ojeda Echevarria F, Zeller T, Schnabel R, Lackner K, Blettner M, Zwiener I, Michal M
PSYCHOTHER PSYCHOSOM. 2012;81(2):108-117.

Long-range DNA looping and gene expression analyses identify DEXI as an autoimmune disease candidate gene.
Davison L, Wallace C, Cooper J, Cope N, Wilson N, Smyth D, Howson J, Saleh N, Al-Jeffery A, Angus K, Stevens H, Nutland S, Duley S, Coulson R, Walker N, Burren O, Rice C, Cambien F, Zeller T, Munzel T, Lackner K, Blankenberg S, Consortium C, Fraser P, Gottgens B, Todd J, Attwood T, Belz S, Braund P, Cambien F, Cooper J, Crisp-Hihn A, Diemert P, Deloukas P, Foad N, Erdmann J, Goodall A, Gracey J, Gray E, Gwilliams R, Heimerl S, Hengstenberg C, Jolley J, Krishnan U, Lloyd-Jones H, Lugauer I, Lundmark P, Maouche S, Moore J, Muir D, Murray E, Nelson C, Neudert J, Niblett D, O'Leary K, Ouwehand W, Pollard H, Rankin A, Sager H, Samani N, Sambrook J, Schmitz G, Scholz M, Schroeder L, Schunkert H, Syvannen A, Tennstedt S
HUM MOL GENET. 2012;21(2):322-333.

Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
Franceschini N, Rooij v, Frank J, Prins B, Feitosa M, Karakas M, Eckfeldt J, Folsom A, Kopp J, Vaez A, Andrews J, Baumert J, Boraska V, Broer L, Hayward C, Ngwa J, Okada Y, Polasek O, Westra H, Wang Y, Fabiola D, Glazer N, Kapur K, Kema I, Lopez L, Schillert A, Smith A, Winkler C, Zgaga L, Study L, Bandinelli S, Bergmann S, Boban M, Bochud M, Chen Y, Davies G, Dehghan A, Ding J, Doering A, Durda J, Ferrucci L, Franco O, Franke L, Gunjaca G, Hofman A, Hsu F, Kolcic I, Kraja A, Kubo M, Lackner K, Launer L, Loehr L, Li G, Meisinger C, Nakamura Y, Schwienbacher C, Starr J, Takahashi A, Torlak V, Uitterlinden A, Vitart V, Waldenberger M, Wild P, Zeller T, Zeller T, Zemunik T, Zhang Q, Blankenberg S, Blankenberg S, Boerwinkle E, Borecki I, Campbell H, Deary I, Frayling T, Gieger C, Harris T, Hicks A, Koenig W, Donnell O, Christopher J, Fox C, Pramstaller P, Psaty B, Reiner A, Rotter J, Rudan I, Snieder H, Tanaka T, Duijn v, Cornelia M, Vollenweider P, Waeber G, Wilson J, Witteman J, Wolffenbuttel B, Wright A, Wu Q, Liu Y, Jenny N, North K, Felix J, Alizadeh B, Cupples L, Perry J, Morris A
AM J HUM GENET. 2012;91(4):744-753.

Comprehensive exploration of the effects of miRNA SNPs on monocyte gene expression.
Greliche N, Zeller T, Wild P, Rotival M, Schillert A, Ziegler A, Deloukas P, Erdmann J, Hengstenberg C, Ouwehand W, Samani N, Schunkert H, Munzel T, Lackner K, Cambien F, Goodall A, Tiret L, Blankenberg S, Trégouët D, Consortium C
PLOS ONE. 2012;7(9):45863.

Population-based meta-analysis in Caucasians confirms association with COL5A1 and ZNF469 but not COL8A2 with central corneal thickness.
Hoehn R, Zeller T, Verhoeven V, Grus F, Adler M, Wolfs R, Uitterlinden A, Castagne R, Schillert A, Klaver C, Pfeiffer N, Mirshahi A
HUM GENET. 2012;131(11):1783-1793.

A multiple biomarker risk score for guiding clinical decisions using a decision curve approach.
Hughes M, Saarela O, Blankenberg S, Zeller T, Havulinna A, Kuulasmaa K, Yarnell J, Schnabel R, Tiret L, Salomaa V, Evans A, Kee F
EUR J PREV CARDIOL. 2012;19(4):874-884.

Prognostic information of glycogen phosphorylase isoenzyme BB in patients with suspected acute coronary syndrome.
Lillpopp L, Tzikas S, Ojeda Echevarria F, Zeller T, Baldus S, Bickel C, Sinning C, Wild P, Genth-Zotz S, Warnholtz A, Lackner K, Münzel T, Blankenberg S, Keller T
AM J CARDIOL. 2012;110(9):1225-1230.

Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies.
Murabito J, White C, Kavousi M, Sun Y, Feitosa M, Nambi V, Lamina C, Schillert A, Coassin S, Bis J, Broer L, Crawford D, Franceschini N, Frikke-Schmidt R, Haun M, Holewijn S, Huffman J, Hwang S, Kiechl S, Kollerits B, Montasser M, Nolte I, Rudock M, Senft A, Teumer A, van der Harst P, Vitart V, Waite L, Wood A, Wassel C, Absher D, Allison M, Amin N, Arnold A, Asselbergs F, Aulchenko Y, Bandinelli S, Barbalic M, Boban M, Brown-Gentry K, Couper D, Criqui M, Dehghan A, den Heijer M, Dieplinger B, Ding J, Dörr M, Espinola-Klein C, Felix S, Ferrucci L, Folsom A, Fraedrich G, Gibson Q, Goodloe R, Gunjaca G, Haltmayer M, Heiss G, Hofman A, Kieback A, Kiemeney L, Kolcic I, Kullo I, Kritchevsky S, Lackner K, Li X, Lieb W, Lohman K, Meisinger C, Melzer D, Mohler E, Mudnic I, Mueller T, Navis G, Oberhollenzer F, Olin J, O'Connell J, O'Donnell C, Palmas W, Penninx B, Petersmann A, Polasek O, Psaty B, Rantner B, Rice K, Rivadeneira F, Rotter J, Seldenrijk A, Stadler M, Summerer M, Tanaka T, Tybjaerg-Hansen A, Uitterlinden A, Gilst v, Wiek H, Vermeulen S, Wild S, Wild P, Zeller T, Zeller T, Zemunik T, Zgaga L, Blankenberg S, Blankenberg S, Boerwinkle E, Campbell H, Cooke J, de Graaf J, Herrington D, Kardia S, Mitchell B, Murray A, Münzel T, Newman A, Oostra B, Rudan I, Shuldiner A, Snieder H, Duijn v, Cornelia M, Völker U, Wright A, Wichmann H, Wilson J, Witteman J, Liu Y, Hayward C, Borecki I, Ziegler A, North K, Cupples L, Kronenberg F
CIRC-CARDIOVASC GENE. 2012;5(1):100-112.

Multiple endothelial biomarkers and noninvasive vascular function in the general population: the Gutenberg Health Study.
Schnabel R, Wild P, Schulz A, Zeller T, Sinning C, Wilde S, Kunde J, Lubos E, Lackner K, Warnholtz A, Gori T, Blankenberg S, Munzel T, Investigators G
HYPERTENSION. 2012;60(2):288-295.

Analyzing illumina gene expression microarray data from different tissues: methodological aspects of data analysis in the metaxpress consortium.
Schurmann C, Heim K, Schillert A, Blankenberg S, Carstensen M, Dörr M, Endlich K, Felix S, Gieger C, Grallert H, Herder C, Hoffmann W, Homuth G, Illig T, Kruppa J, Meitinger T, Müller C, Nauck M, Peters A, Rettig R, Roden M, Strauch K, Völker U, Völzke H, Wahl S, Wallaschofski H, Wild P, Zeller T, Teumer A, Prokisch H, Ziegler A
PLOS ONE. 2012;7(12):50938.

Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium.
Verhoeven V, Hysi P, Saw S, Vitart V, Mirshahi A, Guggenheim J, Cotch M, Yamashiro K, Baird P, Mackey D, Wojciechowski R, Ikram M, Hewitt A, Duggal P, Janmahasatian S, Khor C, Fan Q, Zhou X, Young T, Tai E, Goh L, Li Y, Aung T, Vithana E, Teo Y, Tay W, Sim X, Rudan I, Hayward C, Wright A, Polasek O, Campbell H, Wilson J, Fleck B, Nakata I, Yoshimura N, Yamada R, Matsuda F, Ohno-Matsui K, Nag A, McMahon G, Beate S, Lu Y, Rahi J, Cumberland P, Bhattacharya S, Simpson C, Atwood L, Li X, Raffel L, Murgia F, Portas L, Despriet D, Koolwijk v, Leonieke M, Wolfram C, Lackner K, Tönjes A, Mägi R, Lehtimäki T, Kähönen M, Esko T, Metspalu A, Rantanen T, Pärssinen O, Klein B, Meitinger T, Spector T, Oostra B, Smith A, Jong d, Paulus T, Hofman A, Amin N, Karssen L, Rivadeneira F, Vingerling J, Eiríksdóttir G, Gudnason V, Döring A, Bettecken T, Zeller T, Williams C, Zeller T, Castagné R, Oexle K, Duijn v, Cornelia M, Iyengar S, Mitchell P, Wang J, Höhn R, Pfeiffer N, Bailey-Wilson J, Stambolian D, Wong T, Hammond C, Klaver C
HUM GENET. 2012;131(9):1467-1480.

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study.
Voight B, Peloso G, Orho-Melander M, Frikke-Schmidt R, Barbalic M, Jensen M, Hindy G, Hólm H, Ding E, Johnson T, Schunkert H, Samani N, Clarke R, Hopewell J, Thompson J, Li M, Thorleifsson G, Newton-Cheh C, Musunuru K, Pirruccello J, Saleheen D, Chen L, Stewart A, Schillert A, Thorsteinsdottir U, Thorgeirsson G, Anand S, Engert J, Morgan T, Spertus J, Stoll M, Berger K, Martinelli N, Girelli D, McKeown P, Patterson C, Epstein S, Devaney J, Burnett M, Mooser V, Ripatti S, Surakka I, Nieminen M, Sinisalo J, Lokki M, Perola M, Havulinna A, de Faire U, Gigante B, Ingelsson E, Zeller T, Wild P, Bakker d, Paul I, Klungel O, Anke-Hilse M, Peters B, de Boer A, Grobbee D, Kamphuisen P, Deneer V, Elbers C, Onland-Moret N, Hofker M, Wijmenga C, Verschuren W, Boer J, Schouw v, Yvonne T, Rasheed A, Frossard P, Demissie S, Willer C, Do R, Ordovas J, Abecasis G, Boehnke M, Mohlke K, Daly M, Guiducci C, Burtt N, Surti A, Gonzalez E, Purcell S, Gabriel S, Marrugat J, Peden J, Erdmann J, Diemert P, Willenborg C, König I, Fischer M, Hengstenberg C, Ziegler A, Buysschaert I, Lambrechts D, Frans V, Fox K, Mokhtari E, Eddine N, Rubin D, Schrezenmeir J, Blankenberg S, Schäfer A, Danesh J, Blankenberg S, Roberts R, McPherson R, Watkins H, Hall A, Overvad K, Rimm E, Boerwinkle E, Tybjaerg-Hansen A, Cupples L, Reilly M, Melander O, Mannucci P, Ardissino D, Siscovick D, Elosua R, Stefansson K, O'Donnell C, Salomaa V, Rader D, Peltonen L, Schwartz S, Altshuler D, Kathiresan S
LANCET. 2012;380(9841):572-580.

Midregional proadrenomedullin for prediction of cardiovascular events in coronary artery disease: results from the AtheroGene study.
Wild P, Schnabel R, Lubos E, Zeller T, Sinning C, Keller T, Tzikas S, Lackner K, Peetz D, Rupprecht H, Bickel C, Morgenthaler N, Papassotiriou J, Tiret L, Münzel T, Blankenberg S
CLIN CHEM. 2012;58(1):226-236.

[The Gutenberg Health Study].
Wild P, Zeller T, Beutel M, Blettner M, Dugi K, Lackner K, Pfeiffer N, Münzel T, Blankenberg S
BUNDESGESUNDHEITSBLATT. 2012;55(6-7):824-829.

Genomewide association studies in cardiovascular disease--an update 2011.
Zeller T, Blankenberg S, Diemert P
CLIN CHEM. 2012;58(1):92-103.

Serial changes in highly sensitive troponin I assay and early diagnosis of myocardial infarction.
Keller T, Zeller T, Ojeda Echevarria F, Tzikas S, Lillpopp L, Sinning C, Wild P, Genth-Zotz S, Warnholtz A, Giannitsis E, Möckel M, Bickel C, Peetz D, Lackner K, Baldus S, Münzel T, Blankenberg S
JAMA-J AM MED ASSOC. 2011;306(24):2684-2693.

Noninvasive vascular function measurement in the community: cross-sectional relations and comparison of methods
Schnabel R, Schulz A, Wild P, Sinning C, Wilde S, Eleftheriadis M, Herkenhoff S, Zeller T, Lubos E, Lackner K, Warnholtz A, Gori T, Blankenberg S, Münzel T
CIRC-CARDIOVASC IMAG. 2011;4(4):371-80.

Noninvasive vascular function measurement in the community: cross-sectional relations and comparison of methods.
Schnabel R, Schulz A, Wild P, Sinning C, Wilde S, Eleftheriadis M, Herkenhoff S, Zeller T, Lubos E, Lackner K, Warnholtz A, Gori T, Blankenberg S, Münzel T
CIRC-CARDIOVASC IMAG. 2011;4(4):371-380.

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes
Strawbridge R, Dupuis J, Prokopenko I, Barker A, Ahlqvist E, Rybin D, Petrie J, Travers M, Bouatia-Naji N, Dimas A, Nica A, Wheeler E, Chen H, Voight B, Taneera J, Kanoni S, Peden J, Turrini F, Gustafsson S, Zabena C, Almgren P, Barker D, Barnes D, Dennison E, Eriksson J, Eriksson P, Eury E, Folkersen L, Fox C, Frayling T, Goel A, Gu H, Horikoshi M, Isomaa B, Jackson A, Jameson K, Kajantie E, Kerr-Conte J, Kuulasmaa T, Kuusisto J, Loos R, Luan J, Makrilakis K, Manning A, Martínez-Larrad M, Narisu N, Nastase Mannila M, Ohrvik J, Osmond C, Pascoe L, Payne F, Sayer A, Sennblad B, Silveira A, Stancáková A, Stirrups K, Swift A, Syvänen A, Tuomi T, van 't Hooft F, Walker M, Weedon M, Xie W, Zethelius B, Ongen H, Mälarstig A, Hopewell J, Saleheen D, Chambers J, Parish S, Danesh J, Kooner J, Ostenson C, Lind L, Cooper C, Serrano-Ríos M, Ferrannini E, Forsen T, Clarke R, Franzosi M, Seedorf U, Watkins H, Froguel P, Johnson P, Deloukas P, Collins F, Laakso M, Dermitzakis E, Boehnke M, McCarthy M, Wareham N, Groop L, Pattou F, Gloyn A, Dedoussis G, Lyssenko V, Meigs J, Barroso I, Watanabe R, Ingelsson E, Langenberg C, Hamsten A, Florez J, , Zeller T
DIABETES. 2011;60(10):2624-34.

A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy
Villard E, Perret C, Gary F, Proust C, Dilanian G, Hengstenberg C, Ruppert V, Arbustini E, Wichter T, Germain M, Dubourg O, Tavazzi L, Aumont M, DeGroote P, Fauchier L, Trochu J, Gibelin P, Aupetit J, Stark K, Erdmann J, Hetzer R, Roberts A, Barton P, Regitz-Zagrosek V, Aslam U, Duboscq-Bidot L, Meyborg M, Maisch B, Madeira H, Waldenström A, Galve E, Cleland J, Dorent R, Roizes G, Zeller T, Blankenberg S, Goodall A, Cook S, Tregouet D, Tiret L, Isnard R, Komajda M, Charron P, Cambien F
EUR HEART J. 2011;32(9):1065-76.

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure
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Letzte Aktualisierung aus dem FIS: 22.01.2019 - 04:10 Uhr