• Meka DP, Scharrenberg R, Zhao B, Kobler O, König T, Schaefer I, Schwanke B, Klykov S, Richter M, Eggert D, Windhorst S, Dotti CG, Kreutz MR, Mikhaylova M, Calderon de Anda F.
    Radial somatic F-actin organization affects growth cone dynamics during early neuronal development. EMBO Rep. 2019 Oct 24:e47743. doi: 10.15252/embr.201947743. [Epub ahead of print]
  • Konietzny A, González-Gallego J, Bär J, Perez-Alvarez A, Drakew A, Demmers JAA, Dekkers DHW, Hammer JA 3rd, Frotscher M, Oertner TG, Wagner W, Kneussel M, Mikhaylova M.
    Myosin V regulates synaptopodin clustering and localization in dendrites of hippocampal neurons. J Cell Sci. 2019 Aug 1. pii: jcs.230177. doi: 10.1242/jcs.230177.
  • Marques ARA, Di Spiezio A, Thießen N, Schmidt L, Grötzinger J, Lüllmann-Rauch R, Damme M, Storck SE, Pietrzik CU, Fogh J, Bär J, Mikhaylova M, Glatzel M, Bassal M, Bartsch U, Saftig P.
    Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis.
    Autophagy. 2019 Jul 8. doi: 10.1080/15548627.2019.1637200. [Epub ahead of print]
  • van Bommel B, Konietzny A, Kobler O, Bär J, Mikhaylova M.
    F-actin patches associated with glutamatergic synapses control positioning of dendritic lysosomes.
    EMBO J. 2019 Jun 27:e101183. doi: 10.15252/embj.2018101183.

  • Schiewek J, Schumacher U, Lange T, Joosse SA, Wikman H, Pantel K, Mikhaylova M, Kneussel M, Linder S, Schmalfeldt B, Oliveira-Ferrer L, Windhorst S.
    Clinical relevance of cytoskeleton associated proteins for ovarian cancer.
    J Cancer Res Clin Oncol. 2018 Nov;144(11):2195-2205.
  • Seipold L, Altmeppen H, Koudelka T, Tholey A, Kasparek P, Sedlacek R, Schweizer M, Bär J, Mikhaylova M, Glatzel M, Saftig P. In vivo regulation of the A disintegrin and metalloproteinase 10 (ADAM10) by the tetraspanin 15. Cell Mol Life Sci. 2018 Mar 8.
  • Mikhaylova M, Bär J, van Bommel B, Schätzle P, YuanXiang PY, Raman R, Hradsky J, Konietzny A, Loktionov EY, Reddy PP, Lopez-Rojas J, Spilker C, Kobler O, Raza SA, Stork O, Hoogenraad CC, Kreutz MR (2018). Caldendrin directly couples postsynaptic calcium signals to actin-remodeling in dendritic spines. neuron.2018.01.046.
  • Heinz LS, Muhs S, Schiewek J, Grüb S, Nalaskowski M, Lin YN, Wikman H, Oliveira-Ferrer L, Lange T, Wellbrock J, Konietzny A, Mikhaylova M, Windhorst S.Strong fascin expression promotes metastasis independent of its F-actin bundling activity.
    Oncotarget. 2017 Nov 1;8(66):110077-110091.
  • Zhao B, Meka DP, Scharrenberg R, König T, Schwanke B, Kobler O, Windhorst S, Kreutz MR, Mikhaylova M, Calderon de Anda F.
    Microtubules Modulate F-actin Dynamics during Neuronal Polarization. Sci Rep. 2017 Aug 29;7(1):9583.
  • Cloin BMC, De Zitter E, Salas D, Gielen V, Folkers GE, Mikhaylova M, Bergeler M, Krajnik B, Harvey J, Hoogenraad CC, Van Meervelt L, Dedecker P, Kapitein LC. Efficient switching of mCherry fluorescence using chemical caging. PNAS 2017; published ahead of print June 19, 2017, doi:10.1073/pnas.1617280114.
  • Grochowska KM, Yuanxiang P, Bär J, Raman R, Brugal G, Sahu G, Schweizer M, Bikbaev A, Schilling S, Demuth HU, Kreutz MR. Posttranslational modification impact on the mechanism by which amyloid-β induces synaptic dysfunction. EMBO Rep. 2017 Apr 18. doi: 10.15252/embr.201643519.
  • Katrukha EA*, Mikhaylova M*, van Brakel HX, van Bergen En Henegouwen PM, Akhmanova A, Hoogenraad CC, Kapitein LC. Probing cytoskeletal modulation of passive and active intracellular dynamics using nanobody-functionalized quantum dots. Nat Commun. 2017 Mar 21;8:14772. doi: 10.1038/ncomms14772.
    * shared first authorship
  • Frese CK*, Mikhaylova M*, Stucchi R*, Gautier V, Liu Q, Mohammed S, Heck AJR, Altelaar AFM, Hoogenraad CC. Quantitative Map of Proteome Dynamics during Neuronal Differentiation. Cell Reports. 2017 Feb 7;18 (6): 1527-42.
    * shared first authorship
  • Bär J, Kobler O, van Bommel B, Mikhaylova M. Periodic F-actin structures shape the neck of dendritic spines. Sci Rep. 2016 Nov 14;6:37136. doi: 10.1038/srep37136.
  • Spilker C, Nullmeier S, Grochowska KM, Schumacher A, Butnaru I, Macharadze T, Gomes GM, Yuanxiang P, Bayraktar G, Rodenstein C, Geiseler C, Kolodziej A, Lopez-Rojas J, Montag D, Angenstein F, Bär J, D'Hanis W, Roskoden T, Mikhaylova M, Budinger E, Ohl FW, Stork O, Zenclussen AC, Karpova A, Schwegler H, Kreutz MR.
    A Jacob/Nsmf Gene Knockout Results in Hippocampal Dysplasia and Impaired BDNF Signaling in Dendritogenesis. PLoS Genet. 2016 Mar 15;12(3):e1005907.
  • Bera S, Raghuram V, Mikhaylova M, Kreutz MR.
    A plasmid based expression system to study protein-protein interactions at the Golgi in vivo.
    Anal Biochem. 2016 Mar 10. pii: S0003-2697(16)00086-5.
  • Kevenaar JT, Bianchi S, van Spronsen M, Olieric N, Lipka J, Frias CP, Mikhaylova M, Harterink M, Keijzer N, Wulf PS, Hilbert M, Kapitein LC, de Graaff E, Ahkmanova A, Steinmetz MO, Hoogenraad CC.
    Kinesin-Binding Protein Controls Microtubule Dynamics and Cargo Trafficking by Regulating Kinesin Motor Activity. Curr Biol. 2016 Mar 2. pii: S0960-9822(16)00130-5.
  • Mikhaylova, M.*, Bera, S.*, Kobler, O., Frischknecht, R., and Kreutz, M.R. (2015).
    A dendritic Golgi satellite in between ERGIC and retrome. . Cell Rep. 2016 Jan 12;14(2):189-99. *shared first authorship
  • Mikhaylova M, Cloin BM, Finan K, van den Berg R, Teeuw J, Kijanka MM, Sokolowski M, Katrukha EA, Maidorn M, Opazo F, Moutel S, Vantard M, Perez F, van Bergen En Henegouwen PM, Hoogenraad CC, Ewers H, Kapitein LC. Resolving bundled microtubules using anti-tubulin nanobodies.Nat Commun. 2015 Aug 11;6:7933. doi: 10.1038/ncomms8933.
  • Hradsky J, Bernstein HG, Marunde M, Mikhaylova M, Kreutz MR. Alternative Splicing, Expression and Cellular Localization of Calneuron-1 in the Rat and Human Brain.J Histochem Cytochem. 2015 Oct;63(10):793-804. doi: 10.1369/0022155415595841. Epub 2015 Jun 26.
  • Navarro G, Aguinaga D, Moreno E, Hradsky J, Reddy PP, Cortés A, Mallol J, Casadó V, Mikhaylova M, Kreutz MR, Lluís C, Canela EI, McCormick PJ, Ferré S. Intracellular calcium levels determine differential modulation of allosteric interactions within G protein-coupled receptor heteromers. Chem Biol. 2014 Nov 20;21(11):1546-56.
  • Navarro G, Aguinaga D, Moreno E, Hradsky J, Reddy PP, Cortés A, Mallol J, Casadó V, Mikhaylova M, Kreutz MR, Lluís C, Canela EI, McCormick PJ, Ferré S. Intracellular calcium levels determine differential modulation of allosteric interactions within G protein-coupled receptor heteromers.Chem Biol. 2014 Nov 20;21(11):1546-56. doi: 10.1016/j.chembiol.2014.10.004.
  • Yuanxiang P, Bera S, Karpova A, Kreutz MR, Mikhaylova M. Isolation of CA1 nuclear enriched fractions from hippocampal slices to study activity-dependent nuclear import of synapto-nuclear messenger proteins. J Vis Exp. 2014 Aug 10;(90):e51310. doi: 10.3791/51310.
  • Reddy PP, Raghuram V, Hradsky J, Spilker C, Chakraborty A, Sharma Y, Mikhaylova M, Kreutz MR. Molecular dynamics of the neuronal EF-hand Ca2+-sensor Caldendrin. PLoS One. 2014 Jul 24;9(7):e103186. doi: 10.1371/journal.pone.0103186. eCollection 2014.
  • Mikhaylova M*, Schumacher A*, Borutzki C, Neumann JR, Macharadze T, El-Mousleh T, Wahle P, Zenclussen AC, Kreutz MR. Analysis of Y-P30/Dermcidin expression and properties of the Y-P30 peptide. BMC Res Notes. 2014 Jun 26;7:400. *shared first authorship
  • Yau KW, van Beuningen SF, Cunha-Ferreira I, Cloin BM, van Battum EY, Will L, Schätzle P, Tas RP, van Krugten J, Katrukha EA, Jiang K, Wulf PS, Mikhaylova M, Harterink M, Pasterkamp RJ, Akhmanova A, Kapitein LC, Hoogenraad CC. Microtubule minus-end binding protein CAMSAP2 controls axon specification and dendrite development. Neuron. 2014 Jun 4;82(5):1058-73.
  • Mikhaylova M, Karpova A, Baer J, Bethge P, YuanXiang P, Chen Y, Zuschratter W, Behnisch T, Kreutz MR. Cellular distribution of the NMDA-receptor activated nucleocytoplasmic messenger Jacob in the rat brain. Brain structure and function. 2014 May;219(3):843-60.
  • Karpova A*, Mikhaylova M*, Bera S, Baer J, Reddy PP, Behnisch T, Rankovic V, Spilker C, Bethge P, Sahin J, Kaushik R, Zuschratter W, Kähne T, Naumann M, Gundelfinger ED, Kreutz MR. Encoding and Transducing the Synaptic or Extrasynaptic Origin of NMDA Receptor Signals to the Nucleus. Cell. 2013 Feb 28;152(5):1119-33. *shared first authorship
  • van Spronsen M*, Mikhaylova M*, Lipka J*, Schlager MA, van den Heuvel DJ, Kuijpers M, Wulf PS, Keijzer N, Demmers J, Kapitein LC, Jaarsma D, Gerritsen HC, Akhmanova A, Hoogenraad CC. TRAK/Milton Motor-Adaptor Proteins Steer Mitochondrial Trafficking to Axons and Dendrites. Neuron. 2013 Feb 6;77(3):485-502. *shared first authorship
  • Hradsky J*, Mikhaylova M*, Karpova A, Kreutz MR, Zuschratter W.Super-resolution microscopy of the neuronal calcium-binding proteins Calneuron-1 and Caldendrin. Methods Mol Biol. 2013;963:147-69.
    *shared first authorship
  • Gorny X, Mikhaylova M, Seeger C, Reddy PP, Reissner C, Schott BH, Helena Danielson U, Kreutz MR, Seidenbecher C. AKAP79/150 interacts with the neuronal calcium-binding protein caldendrin. J Neurochem. 2012 Aug;122(4):714-26.
  • Navarro G, Hradsky J, Lluís C, Casadó V, McCormick PJ, Kreutz MR, Mikhaylova M*. NCS-1 associates with adenosine A(2A) receptors and modulates receptor function. Front Mol Neurosci. 2012;5:53. *corresponding authorship
  • Hradsky J, Raghuram V, Reddy PP, Navarro G, Hupe M, Casado V, McCormick PJ, Sharma Y, Kreutz MR*, Mikhaylova M*. Post-translational membrane insertion of tail-anchored transmembrane EF-hand Ca2+ sensor calneurons requires the TRC40/Asna1 protein chaperone. J Biol Chem. 2011 Oct 21;286(42):36762-76. *shared corresponding authorship
  • Ronicke R, Mikhaylova M, Ronicke S, Meinhardt J, Schroder U, Fändrich M, Reiser G, Kreutz MR, Reymann KG. Early neuronal dysfunction by amyloid beta oligomers depends on activation of NR2B-containing NMDA receptors. Neurobiol Aging. 2011 Dec;32(12):2219-28.
  • Behnisch T, Yuanxiang P, Bethge P, Parvez S, Chen Y, Yu J, Karpova A, Frey JU, Mikhaylova M, Kreutz MR. Nuclear translocation of jacob in hippocampal neurons after stimuli inducing long-term potentiation but not long-term depression. PLoS One. 2011 Feb 18;6(2):e17276.
  • Vandanapu RR, Singh AK, Mikhaylova M, Reddy PP, Sharma Y, Kreutz MR. Structural differences between the SH3-HOOK-GuK domains of SAP90/PSD-95 and SAP97. Protein Expr Purif. 2009 Dec;68(2):201-7. *shared corresponding authorship
  • Kindler S, Dieterich DC, Sch ütt J, Sahin J, Karpova A, Mikhaylova M, Gundelfinger ED, Kreienkamp H-J, Kreutz MR. Dendritic mRNA targeting of Jacob and NMDA-induced nuclear translocation after Calpain-mediated proteolysis. J. Biol. Chem. 2009 Sep 11;284(37):25431-40.
  • Mikhaylova M, Pasham P, Munsch T, Suman S, Smalla K-H, Gundelfinger ED, Sharma Y, Kreutz MR. Calneurons provide a Calcium-threshold for trans-Golgi network to plasma membrane trafficking. Proc. Natl. Acad. Sci. U.S.A., 2009 106(22):9093-8.
  • Smalla K-H, Mikhaylova M, Sahin J, Bernstein H-G, Bogerts B, Roel van der Schors, August B. Smit AB, Li KW, Gundelfinger ED, Kreutz MR. A comparison of the synaptic proteome in human chronic schizophrenia and rat ketamine psychosis suggest that Prohibitin is involved in the synaptic pathology of schizophrenia. Mol Psychiatry. 2008 13(9):878-96.
  • Dieterich DC*, Karpova A*, Mikhaylova M*, Zdobnova I, König I, Landwehr M, Kreutz M, Smalla KH, Richter K, Landgraf P, Reissner C, Böckers TM, Zuschratter W, Spilker C, Seidenbecher CI, Garner CC, Gundelfinger ED, Kreutz MR. Caldendrin – Jacob: A Protein Liaison that Couples NMDA Receptor Signalling to the Nucleus. PLoS Biology 2008 6(2):e34. *shared first authorship
  • Mikhaylova M, Vakhitova JV, Yamidanov RS, Salimgareeva MKh, Seredenin SB, Behnisch T. The effects of ladasten on dopaminergic neurotransmission and hippocampal synaptic plasticity in rats. Neuropharmacology. 2007 53(5):601-8.
  • Mikhaylova M, Sharma Y, Reissner C, Nagel F, Aravind P, Rajini B, Smalla, K-H, Gundelfinger, ED, Kreutz MR. Neuronal Ca2+-signaling via Caldendrin and Calneurons. Biochim Biophys Acta, Mol Cell Res., 2006 1763(11):1229-37.
  • Karpova A, Mikhaylova M, Thomas U, Knöpfel T, Behnisch T. Involvement of protein synthesis and degradation in long term potentiation of Schaffer collateral CA1 synapses. J Neurosci. 2006 26(18):4949-55.


  • Cloin BC, Hoogenraad CC, Mikhaylova M*, Kapitein LC* Single Molecule Localization Microscopy to Study Neuronal Microtubule Organization. Book chapter in Immunocytochemistry and Related Techniques edited by Merigni A and Lossi A, Springer ISBN 978-1-4939-2323-7, 2015. *shared correspondence


  • Bucher M, Fanutza T, Mikhaylova M. Cytoskeletal makeup of the synapse: shaft vs. spine. Cytoskeleton (Hoboken). 2019 Nov 24. doi: 10.1002/cm.21583. [Epub ahead of print] Review.
  • Konietzny A, Bär J, Mikhaylova M. Dendritic Actin Cytoskeleton: Structure, Functions, and Regulations. Front. Cell. Neurosci. 2017 May 18; 11. doi: 10.3389/fncel.2017.00147. Review
  • Van Bommel B, Mikhaylova M. Talking to the neighbours: The molecular and physiological mechanisms of clustered synaptic plasticity. Neurosci Biobehav Rev. 2016 Sep 19;71:352-361. doi: 10.1016/j.neubiorev.2016.09.016. Review.
  • Mikhaylova M, Hradsky J, Kreutz MR. Between promiscuity and specificity: Novel roles of EF-hand calcium sensors in neuronal Ca2+ signalling. J Neurochem. 2011 Sep;118(5):695-713.

  • Mikhaylova M*, Reddy PP and Kreutz MR. Role of neuronal calcium-sensor proteins in Golgi-cell-surface membrane traffic. Biochem Soc Trans. 2010 Feb;38(Pt 1):177-80. Review

    *corresponding authorship