Panagiotis Karagiannis
Dr. med.
Panagiotis Karagiannis
  • Medical specialist
  • Medical Specialist in Internal Medicine and Hematology and Oncology
Working area


O24 , 5th Floor
German (Mother tongue)

Areas of expertise




  • 2023
  • 2022
  • 2021
  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011
  • 2010
  • 2009
  • 2007

Anti-cancer pro-inflammatory effects of an IgE antibody targeting the melanoma-associated antigen chondroitin sulfate proteoglycan 4
Chauhan J, Grandits M, Palhares L, Mele S, Nakamura M, López-Abente J, Crescioli S, Laddach R, Romero-Clavijo P, Cheung A, Stavraka C, Chenoweth A, Sow H, Chiaruttini G, Gilbert A, Dodev T, Koers A, Pellizzari G, Ilieva K, Man F, Ali N, Hobbs C, Lombardi S, Lionarons D, Gould H, Beavil A, Geh J, MacKenzie Ross A, Healy C, Calonje E, Downward J, Nestle F, Tsoka S, Josephs D, Blower P, Karagiannis P, Lacy K, Spicer J, Karagiannis S, Bax H
NAT COMMUN. 2023;14(1):2192.

CLDN6-specific CAR-T cells plus amplifying RNA vaccine in relapsed or refractory solid tumors: the phase 1 BNT211-01 trial
Mackensen A, Haanen J, Koenecke C, Alsdorf W, Wagner-Drouet E, Borchmann P, Heudobler D, Ferstl B, Klobuch S, Bokemeyer C, Desuki A, Lüke F, Kutsch N, Müller F, Smit E, Hillemanns P, Karagiannis P, Wiegert E, He Y, Ho T, Kang-Fortner Q, Schlitter A, Schulz-Eying C, Finlayson A, Flemmig C, Kühlcke K, Preußner L, Rengstl B, Türeci Ö, Şahin U
NAT MED. 2023;29(11):2844-2853.

Innate stimulation of B cells ex vivo enhances antibody secretion and identifies tumour-reactive antibodies from cancer patients
Karagiannis P, Correa I, Chauhan J, Cheung A, Dominguez-Rodriguez D, Terranova Barberio M, Harris R, Crescioli S, Spicer J, Bokemeyer C, Lacy K, Karagiannis S
CLIN EXP IMMUNOL. 2022;207(1):84-94.

Retrospective analysis of three induction chemotherapy regimens in acute myeloid leukemia including CPX-351, cytarabine/daunorubicin with and without the addition of cladribine
Klingler F, Alsdorf W, Ghandili S, Wolschke C, Brauneck F, Bokemeyer C, Fiedler W, Modemann F, Karagiannis P
LEUKEMIA LYMPHOMA. 2022;63(11):2645-2651.

Immunotherapy in Advanced Prostate Cancer-Light at the End of the Tunnel?
von Amsberg G, Alsdorf W, Karagiannis P, Coym A, Kaune M, Werner S, Graefen M, Bokemeyer C, Merkens L, Dyshlovoy S
INT J MOL SCI. 2022;23(5):.

Standardized supportive care documentation improves safety of high-dose methotrexate treatment
Alsdorf W, Karagiannis P, Langebrake C, Bokemeyer C, Frenzel C
ONCOLOGIST. 2021;26(2):e327-e332.

Treatment of refractory acute myeloid leukaemia during pregnancy with venetoclax, high-dose cytarabine and mitoxantrone
Karagiannis P, Alsdorf W, Tallarek A, Blohm M, Oelrich J, Waizenegger J, Wolschke C, Hecher K, Singer D, Bokemeyer C, Fiedler W
BRIT J HAEMATOL. 2021;192(2):e60-e63.

In vivo trafficking of a tumor-targeting IgE antibody: molecular imaging demonstrates rapid hepatobiliary clearance compared to IgG counterpart
Man F, Koers A, Karagiannis P, Josephs D, Bax H, Gilbert A, Dodev T, Mele S, Chiarruttini G, Crescioli S, Chauhan J, Blower J, Cooper M, Spicer J, Karagiannis S, Blower P
ONCOIMMUNOLOGY. 2021;10(1):.

Multi-dimensional and longitudinal systems profiling reveals predictive pattern of severe COVID-19
Woo M, Haag F, Nierhaus A, Jarczak D, Roedl K, Mayer C, Brehm T, van der Meirschen M, Hennigs A, Christopeit M, Fiedler W, Karagiannis P, Burdelski C, Schultze A, Huber S, Addo M, Schmiedel S, Friese M, Kluge S, Schulze Zur Wiesch J
ISCIENCE. 2021;24(7):102752.

Schwere sekundär sklerosierende Cholangitis als Manifestation einer sehr seltenen Grunderkrankung
Zecher B, Zenouzi R, Lang M, Karagiannis P, Clauditz T, Fischer L, Sterneck M, Schramm C, Lohse A, Sebode M
INTERNIST. 2021;62(12):1349-1353.

Challenges in treatment of patients with acute leukemia and COVID-19: a series of 12 patients
Ghandili S, Pfefferle S, Roedl K, Sonnemann P, Karagiannis P, Boenisch O, Kluge S, Schmiedel S, Ittrich H, Rohde H, Lütgehetmann M, Weisel K, Bokemeyer C, Wichmann D, Fiedler W, Jarczak D, Modemann F
BLOOD ADV. 2020;4(23):5936-5941.

Intensive Care Outcomes of Patients after High Dose Chemotherapy and Subsequent Autologous Stem Cell Transplantation: A Retrospective, Single Centre Analysis
Karagiannis P, Sänger L, Alsdorf W, Weisel K, Fiedler W, Kluge S, Wichmann D, Bokemeyer C, Fuhrmann V
CANCERS. 2020;12(6):.

Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance
Orgaz J, Crosas-Molist E, Sadok A, Perdrix-Rosell A, Maiques O, Rodriguez-Hernandez I, Monger J, Mele S, Georgouli M, Bridgeman V, Karagiannis P, Lee R, Pandya P, Boehme L, Wallberg F, Tape C, Karagiannis S, Malanchi I, Sanz-Moreno V
CANCER CELL. 2020;37(1):85-103.e9.

Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment
Georgouli M, Herraiz C, Crosas-Molist E, Fanshawe B, Maiques O, Perdrix A, Pandya P, Rodriguez-Hernandez I, Ilieva K, Cantelli G, Karagiannis P, Mele S, Lam H, Josephs D, Matias-Guiu X, Marti R, Nestle F, Orgaz J, Malanchi I, Fruhwirth G, Karagiannis S, Sanz-Moreno V
CELL. 2019;176(4):757-774.e23.

Evaluation of Antigen-Conjugated Fluorescent Beads to Identify Antigen-Specific B Cells
Correa I, Ilieva K, Crescioli S, Lombardi S, Figini M, Cheung A, Spicer J, Tutt A, Nestle F, Karagiannis P, Lacy K, Karagiannis S
FRONT IMMUNOL. 2018;9:493.

An immunologically relevant rodent model demonstrates safety of therapy using a tumour-specific IgE
Josephs D, Nakamura M, Bax H, Dodev T, Muirhead G, Saul L, Karagiannis P, Ilieva K, Crescioli S, Gazinska P, Woodman N, Lomardelli C, Kareemaghay S, Selkirk C, Lentfer H, Barton C, Canevari S, Figini M, Downes N, Dombrowicz D, Corrigan C, Nestle F, Jones P, Gould H, Blower P, Tsoka S, Spicer J, Karagiannis S
ALLERGY. 2018;73(12):2328-2341.

Functionally Active Fc Mutant Antibodies Recognizing Cancer Antigens Generated Rapidly at High Yields
Ilieva K, Fazekas-Singer J, Achkova D, Dodev T, Mele S, Crescioli S, Bax H, Cheung A, Karagiannis P, Correa I, Figini M, Marlow R, Josephs D, Beavil A, Maher J, Spicer J, Jensen-Jarolim E, Tutt A, Karagiannis S
FRONT IMMUNOL. 2017;8:1112.

AllergoOncology - the impact of allergy in oncology: EAACI position paper
Jensen-Jarolim E, Bax H, Bianchini R, Capron M, Corrigan C, Castells M, Dombrowicz D, Daniels-Wells T, Fazekas J, Fiebiger E, Gatault S, Gould H, Janda J, Josephs D, Karagiannis P, Levi-Schaffer F, Meshcheryakova A, Mechtcheriakova D, Mekori Y, Mungenast F, Nigro E, Penichet M, Redegeld F, Saul L, Singer J, Spicer J, Siccardi A, Spillner E, Turner M, Untersmayr E, Vangelista L, Karagiannis S
ALLERGY. 2017;72(6):866-887.

Anti-folate receptor-α IgE but not IgG recruits macrophages to attack tumors via TNF-α/MCP-1 signaling
Josephs D, Bax H, Dodev T, Georgouli M, Nakamura M, Pellizzari G, Saul L, Karagiannis P, Cheung A, Herraiz C, Ilieva K, Correa I, Fittall M, Crescioli S, Gazinska P, Woodman N, Mele S, Chiaruttini G, Gilbert A, Koers A, Bracher M, Selkirk C, Lentfer H, Barton C, Lever E, Muirhead G, Tsoka S, Canevari S, Figini M, Montes A, Downes N, Dombrowicz D, Corrigan C, Beavil A, Nestle F, Jones P, Gould H, Sanz-Moreno V, Blower P, Spicer J, Karagiannis S
CANCER RES. 2017;77(5):1127-1141.

IgG4 Characteristics and Functions in Cancer Immunity
Crescioli S, Correa I, Karagiannis P, Davies A, Sutton B, Nestle F, Karagiannis S
CURR ALLERGY ASTHM R. 2016;16(1):7.

IgG subclass switching and clonal expansion in cutaneous melanoma and normal skin
Saul L, Ilieva K, Bax H, Karagiannis P, Correa I, Rodriguez-Hernandez I, Josephs D, Tosi I, Egbuniwe I, Lombardi S, Crescioli S, Hobbs C, Villanova F, Cheung A, Geh J, Healy C, Harries M, Sanz-Moreno V, Fear D, Spicer J, Lacy K, Nestle F, Karagiannis S
SCI REP-UK. 2016;6:29736.

TGF-β-Induced Transcription Sustains Amoeboid Melanoma Migration and Dissemination
Cantelli G, Orgaz J, Rodriguez-Hernandez I, Karagiannis P, Maiques O, Matias-Guiu X, Nestle F, Marti R, Karagiannis S, Sanz-Moreno V
CURR BIOL. 2015;25(22):2899-914.

[18F]FE@SUPPY: a suitable PET tracer for the adenosine A3 receptor? An in vivo study in rodents
Haeusler D, Kuntner C, Nics L, Savli M, Zeilinger M, Wanek T, Karagiannis P, Lanzenberger R, Langer O, Shanab K, Spreitzer H, Wadsak W, Hacker M, Mitterhauser M
EUR J NUCL MED MOL I. 2015;42(5):741-9.

Three Huntington's Disease Specific Mutation-Carrying Human Embryonic Stem Cell Lines Have Stable Number of CAG Repeats upon In Vitro Differentiation into Cardiomyocytes
Jacquet L, Neueder A, Földes G, Karagiannis P, Hobbs C, Jolinon N, Mioulane M, Sakai T, Harding S, Ilic D
PLOS ONE. 2015;10(5):e0126860.

Alveolar rhabdomyosarcoma confined to the bone marrow with no identifiable primary tumour using FDG-PET/CT
Karagiannis P, Guth N, Thoennissen G, Bern C, Sperveslage J, Oschlies I, Bokemeyer C, Klapper W, Wardelmann E, Thoennissen N
Clin Sarcoma Res. 2015;5:24.

Elevated IgG4 in patient circulation is associated with the risk of disease progression in melanoma
Karagiannis P, Villanova F, Josephs D, Correa I, Van Hemelrijck M, Hobbs C, Saul L, Egbuniwe I, Tosi I, Ilieva K, Kent E, Calonje E, Harries M, Fentiman I, Taylor-Papadimitriou J, Burchell J, Spicer J, Lacy K, Nestle F, Karagiannis S
ONCOIMMUNOLOGY. 2015;4(11):e1032492.

A tool kit for rapid cloning and expression of recombinant antibodies
Dodev T, Karagiannis P, Gilbert A, Josephs D, Bowen H, James L, Bax H, Beavil R, Pang M, Gould H, Karagiannis S, Beavil A
SCI REP-UK. 2014;4:5885.

Effects of BRAF mutations and BRAF inhibition on immune responses to melanoma
Ilieva K, Correa I, Josephs D, Karagiannis P, Egbuniwe I, Cafferkey M, Spicer J, Harries M, Nestle F, Lacy K, Karagiannis S
MOL CANCER THER. 2014;13(12):2769-83.

IgE immunotherapy: a novel concept with promise for the treatment of cancer
Josephs D, Spicer J, Karagiannis P, Gould H, Karagiannis S
MABS-AUSTIN. 2014;6(1):54-72.

Evaluating biomarkers in melanoma
Karagiannis P, Fittall M, Karagiannis S
FRONT ONCOL. 2014;4:383.

Diverse matrix metalloproteinase functions regulate cancer amoeboid migration
Orgaz J, Pandya P, Dalmeida R, Karagiannis P, Sanchez-Laorden B, Viros A, Albrengues J, Nestle F, Ridley A, Gaggioli C, Marais R, Karagiannis S, Sanz-Moreno V
NAT COMMUN. 2014;5:4255.

3D In vitro model of a functional epidermal permeability barrier from human embryonic stem cells and induced pluripotent stem cells
Petrova A, Celli A, Jacquet L, Dafou D, Crumrine D, Hupe M, Arno M, Hobbs C, Cvoro A, Karagiannis P, Devito L, Sun R, Adame L, Vaughan R, McGrath J, Mauro T, Ilic D
STEM CELL REP. 2014;2(5):675-89.

Comparative reactivity of human IgE to cynomolgus monkey and human effector cells and effects on IgE effector cell potency
Saul L, Josephs D, Cutler K, Bradwell A, Karagiannis P, Selkirk C, Gould H, Jones P, Spicer J, Karagiannis S
MABS-AUSTIN. 2014;6(2):509-22.

IgG4 subclass antibodies impair antitumor immunity in melanoma
Karagiannis P, Gilbert A, Josephs D, Ali N, Dodev T, Saul L, Correa I, Roberts L, Beddowes E, Koers A, Hobbs C, Ferreira S, Geh J, Healy C, Harries M, Acland K, Blower P, Mitchell T, Fear D, Spicer J, Lacy K, Nestle F, Karagiannis S
J CLIN INVEST. 2013;123(4):1457-74.

IgG4 antibodies and cancer-associated inflammation: Insights into a novel mechanism of immune escape
Karagiannis P, Gilbert A, Nestle F, Karagiannis S
ONCOIMMUNOLOGY. 2013;2(7):e24889.

Immunoglobulin E and Allergy: Antibodies in Immune Inflammation and Treatment
Karagiannis S, Karagiannis P, Josephs D, Saul L, Gilbert A, Upton N, Gould H

Resident CD141 (BDCA3)+ dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation
Chu C, Ali N, Karagiannis P, Di Meglio P, Skowera A, Napolitano L, Barinaga G, Grys K, Sharif-Paghaleh E, Karagiannis S, Peakman M, Lombardi G, Nestle F
J EXP MED. 2012;209(5):935-45.

Recombinant IgE antibodies for passive immunotherapy of solid tumours: from concept towards clinical application
Karagiannis S, Josephs D, Karagiannis P, Gilbert A, Saul L, Rudman S, Dodev T, Koers A, Blower P, Corrigan C, Beavil A, Spicer J, Nestle F, Gould H
CANCER IMMUNOL IMMUN. 2012;61(9):1547-64.

Toward prediction of immune mechanisms and design of immunotherapies in melanoma
Tsoka S, Ainali C, Karagiannis P, Josephs D, Saul L, Nestle F, Karagiannis S
CRIT REV BIOMED ENG. 2012;40(4):279-94.

Monitoring the systemic human memory B cell compartment of melanoma patients for anti-tumor IgG antibodies
Gilbert A, Karagiannis P, Dodev T, Koers A, Lacy K, Josephs D, Takhar P, Geh J, Healy C, Harries M, Acland K, Rudman S, Beavil R, Blower P, Beavil A, Gould H, Spicer J, Nestle F, Karagiannis S
PLOS ONE. 2011;6(4):e19330.

Antacids and dietary supplements with an influence on the gastric pH increase the risk for food sensitization
Pali-Schöll I, Herzog R, Wallmann J, Szalai K, Brunner R, Lukschal A, Karagiannis P, Diesner S, Jensen-Jarolim E
CLIN EXP ALLERGY. 2010;40(7):1091-8.

Aluminium per se and in the anti-acid drug sucralfate promotes sensitization via the oral route
Brunner R, Wallmann J, Szalai K, Karagiannis P, Altmeppen H, Riemer A, Jensen-Jarolim E, Pali-Schöll I
ALLERGY. 2009;64(6):890-7.

Characterisation of an engineered trastuzumab IgE antibody and effector cell mechanisms targeting HER2/neu-positive tumour cells
Karagiannis P, Singer J, Hunt J, Gan S, Rudman S, Mechtcheriakova D, Knittelfelder R, Daniels T, Hobson P, Beavil A, Spicer J, Nestle F, Penichet M, Gould H, Jensen-Jarolim E, Karagiannis S
CANCER IMMUNOL IMMUN. 2009;58(6):915-30.

The impact of aluminium in acid-suppressing drugs on the immune response of BALB/c mice
Brunner R, Wallmann J, Szalai K, Karagiannis P, Kopp T, Scheiner O, Jensen-Jarolim E, Pali-Schöll I
CLIN EXP ALLERGY. 2007;37(10):1566-73.

Letzte Aktualisierung aus dem FIS: 11.12.2023 - 04:42 Uhr