Dr. med.
Davor Lessel
  • Physician
Working area

Location

Campus Forschung N27 , Ground Floor, Room number 00.093
Languages
Croatian (Mother tongue)
German
English

Areas of expertise

Publications

2017

Lessons learned from additional research analyses of unsolved clinical exome cases
Eldomery M, Coban-Akdemir Z, Harel T, Rosenfeld J, Gambin T, Stray-Pedersen A, Küry S, Mercier S, Lessel D, Denecke J, Wiszniewski W, Penney S, Liu P, Bi W, Lalani S, Schaaf C, Wangler M, Bacino C, Lewis R, Potocki L, Graham B, Belmont J, Scaglia F, Orange J, Jhangiani S, Chiang T, Doddapaneni H, Hu J, Muzny D, Xia F, Beaudet A, Boerwinkle E, Eng C, Plon S, Sutton V, Gibbs R, Posey J, Yang Y, Lupski J
GENOME MED. 2017;9(1):26.

Compound heterozygous GATA5 mutations in a girl with hydrops fetalis, congenital heart defects and genital anomalies
Hempel M, Casar Tena T, Diehl T, Burczyk M, Strom T, Kubisch C, Philipp M, Lessel D
HUM GENET. 2017;136(3):339-346.

Phenotypes and genotypes in individuals with SMC1A variants
Huisman S, Mulder P, Redeker E, Bader I, Bisgaard A, Brooks A, Cereda A, Cinca C, Clark D, Cormier-Daire V, Deardorff M, Diderich K, Elting M, van Essen A, Patrick D, Gervasini C, Gillessen-Kaesbach G, Girisha K, Hilhorst-Hofstee Y, Hopman S, Horn D, Isrie M, Jansen S, Jespersgaard C, Kaiser F, Kaur M, Kleefstra T, Krantz I, Lakeman P, Landlust A, Lessel D, Michot C, Moss J, Noon S, Oliver C, Parenti I, Pie J, Ramos F, Rieubland C, Russo S, Selicorni A, Tümer Z, Vorstenbosch R, Wenger T, van Balkom I, Piening S, Wierzba J, Hennekam R
AM J MED GENET A. 2017;173(8):2108-2125.

First de novo ANK3 nonsense mutation in a boy with intellectual disability, speech impairment and autistic features
Kloth K, Denecke J, Hempel M, Johannsen J, Strom T, Kubisch C, Lessel D
EUR J MED GENET. 2017;60(9):494-498.

Dysfunction of the MDM2/p53 axis is linked to premature aging
Lessel D, Wu D, Trujillo C, Ramezani T, Lessel I, Alwasiyah M, Saha B, Hisama F, Rading K, Goebel I, Schütz P, Speit G, Högel J, Thiele H, Nürnberg G, Nürnberg P, Hammerschmidt M, Zhu Y, Tong D, Katz C, Martin G, Oshima J, Prives C, Kubisch C
J CLIN INVEST. 2017 [Epub ahead of print].

Mutations in EXTL3 Cause Neuro-immuno-skeletal Dysplasia Syndrome
Oud M, Tuijnenburg P, Hempel M, van Vlies N, Ren Z, Ferdinandusse S, Jansen M, Santer R, Johannsen J, Bacchelli C, Alders M, Li R, Davies R, Dupuis L, Cale C, Wanders R, Pals S, Ocaka L, James C, Müller I, Lehmberg K, Strom T, Engels H, Williams H, Beales P, Roepman R, Dias P, Brunner H, Cobben J, Hall C, Hartley T, Le Quesne Stabej P, Mendoza-Londono R, Davies E, de Sousa S, Lessel D, Arts H, Kuijpers T
AM J HUM GENET. 2017;100(2):281-296.

Survival beyond the perinatal period expands the phenotypes caused by mutations in GLE1
Said E, Chong J, Hempel M, Denecke J, Soler P, Strom T, Nickerson D, Kubisch C, Bamshad M, Lessel D
AM J MED GENET A. 2017 [Epub ahead of print].

WRN Mutation Update: Mutation Spectrum, Patient Registries, and Translational Prospects.
Yokote K, Chanprasert S, Lee L, Eirich K, Takemoto M, Watanabe A, Koizumi N, Lessel D, Mori T, Hisama F, Ladd P, Angle B, Baris H, Cefle K, Palanduz S, Ozturk S, Chateau A, Deguchi K, Easwar T, Federico A, Fox A, Grebe T, Hay B, Nampoothiri S, Seiter K, Streeten E, Piña-Aguilar R, Poke G, Poot M, Posmyk R, Martin G, Kubisch C, Schindler D, Oshima J
HUM MUTAT. 2017;38(1):7-15.

2016

Phenotype and genotype in patients with Larsen syndrome: clinical homogeneity and allelic heterogeneity in seven patients
Girisha K, Bidchol A, Graul-Neumann L, Gupta A, Hehr U, Lessel D, Nader S, Shah H, Wickert J, Kutsche K
BMC MED GENET. 2016;17:27.

De Novo Mutations in SON Disrupt RNA Splicing of Genes Essential for Brain Development and Metabolism, Causing an Intellectual-Disability Syndrome
Kim J, Shinde D, Reijnders M, Hauser N, Belmonte R, Wilson G, Bosch D, Bubulya P, Shashi V, Petrovski S, Stone J, Park E, Veltman J, Sinnema M, Stumpel C, Draaisma J, Nicolai J, Yntema H, Lindstrom K, de Vries B, Jewett T, Santoro S, Vogt J, Bachman K, Seeley A, Krokosky A, Turner C, Rohena L, Hempel M, Kortüm F, Lessel D, Neu A, Strom T, Wieczorek D, Bramswig N, Laccone F, Behunova J, Rehder H, Gordon C, Rio M, Romana S, Tang S, El-Khechen D, Cho M, McWalter K, Douglas G, Baskin B, Begtrup A, Funari T, Schoch K, Stegmann A, Stevens S, Zhang D, Traver D, Yao X, MacArthur D, Brunner H, Mancini G, Myers R, Owen L, Lim S, Stachura D, Vissers L, Ahn E
AM J HUM GENET. 2016;99(3):711-9.

The analysis of heterotaxy patients reveals new loss-of-function variants of GRK5
Lessel D, Muhammad T, Casar Tena T, Moepps B, Burkhalter M, Hitz M, Toka O, Rentzsch A, Schubert S, Schalinski A, Bauer U, Kubisch C, Ware S, Philipp M
SCI REP-UK. 2016;6:33231.

2015

De Novo Mutations in CHAMP1 Cause Intellectual Disability with Severe Speech Impairment
Hempel M, Cremer K, Ockeloen C, Lichtenbelt K, Herkert J, Denecke J, Haack T, Zink A, Becker J, Wohlleber E, Johannsen J, Alhaddad B, Pfundt R, Fuchs S, Wieczorek D, Strom T, van Gassen K, Kleefstra T, Kubisch C, Engels H, Lessel D
AM J HUM GENET. 2015;97(3):493-500.

Suppressor of cytokine signaling 1 gene mutation status as a prognostic biomarker in classical Hodgkin lymphoma
Lennerz J, Hoffmann K, Bubolz A, Lessel D, Welke C, Rüther N, Viardot A, Möller P
ONCOTARGET. 2015;6(30):29097-110.

POLD1 Germline Mutations in Patients Initially Diagnosed with Werner Syndrome
Lessel D, Hisama F, Szakszon K, Saha B, Sanjuanelo A, Salbert B, Steele P, Baldwin J, Brown W, Piussan C, Plauchu H, Szilvássy J, Horkay E, Högel J, Martin G, Herr A, Oshima J, Kubisch C
HUM MUTAT. 2015;36(11):1070-9.

2014

Atypical Aicardi-Goutieres syndrome - is the WRN locus a modifier?
Lessel D, Saha B, Hisama F, Kaymakamzade B, Nurlu G, Gursoy-Özdemir Y, Thiele H, Nürnberg P, Martin G, Kubisch C, Oshima J
AM J MED GENET A. 2014;164A(10):2510-3.

Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid features
Lessel D, Vaz B, Halder S, Lockhart P, Marinovic-Terzic I, Lopez-Mosqueda J, Philipp M, Sim J, Smith K, Oehler J, Cabrera E, Freire R, Pope K, Nahid A, Norris F, Leventer R, Delatycki M, Barbi G, von Ameln S, Högel J, Degoricija M, Fertig R, Burkhalter M, Hofmann K, Thiele H, Altmüller J, Nürnberg G, Nürnberg P, Bahlo M, Martin G, Aalfs C, Oshima J, Terzic J, Amor D, Dikic I, Ramadan K, Kubisch C
NAT GENET. 2014;46(11):1239-44.

KIT mutations in primary mediastinal B-cell lymphoma
Nagel P, Stenzinger A, Feld F, Herrmann M, Brüderlein S, Barth T, Marienfeld R, Endris V, Weichert W, Debatin K, Westhoff M, Lessel D, Möller P, Lennerz J
BLOOD CANCER J. 2014;4(8):e241.

Chromatin retention of DNA damage sensors DDB2 and XPC through loss of p97 segregase causes genotoxicity
Puumalainen M, Lessel D, Rüthemann P, Kaczmarek N, Bachmann K, Ramadan K, Naegeli H
NAT COMMUN. 2014;5:3695.

Carpal tunnel syndrome is associated with high fibrinogen and fibrinogen deposits
Utrobičić I, Novak I, Marinović-Terzić I, Matić K, Lessel D, Salamunić I, Babić M, Kunac N, Mešin A, Kubisch C, Maček B, Terzić J
NEUROSURGERY. 2014;75(3):276-85.

Letzte Aktualisierung aus dem FIS: 23.10.2017 - 04:55 Uhr