Selected Publications
Loers G, Liao Y, Hu C, Xue W, Shen H1, Zhao W, Schachner M (2019) Identification and characterization of synthetic chondroitin-4-sulfate binding peptides in neuronal functions. Sci Rep 9:1064.
Sahu S, Li R, Loers G, Schachner M (2019) Knockdown of chondroitin-4-sulfotransferase-1, but not of dermatan-4-sulfotransferase-1, accelerates regeneration of zebrafish after spinal cord injury. FASEB J 33:2252-2262.
Grüner F, Blumendorf F, Schmutzler O, Staufer T, Bradbury M, Wiesner U, Rosentreter T, Loers G, Lutz D, Richter B, Fischer M, Schulz F, Steiner S, Warmer M, Burkhardt A, Meents A, Kupinski M, Hoeschen C (2018) Localising functionalised gold-nanoparticles in murine spinal cords by X-ray fluorescence imaging and background-reduction through spatial filtering for human-sized objects. Sci Rep 8:16561.
Guseva D, Jakovcevski I, Irintchev A, Leshchyns'ka I, Sytnyk V, Ponimaskin E, Schachner M (2018) Cell adhesion molecule close homolog of L1 (CHL1) guides the regrowth of regenerating motor axons and regulates synaptic coverage of motor neurons. Front Mol Neurosci 11:174.
Kraus K, Kleene R, Braren I, Loers G, Lutz D, Schachner M (2018) A fragment of adhesion molecule L1 is imported into mitochondria, and regulates mitochondrial metabolism and trafficking. J Cell Sci 131. doi: 10.1242/jcs.210500.
Kraus K, Kleene R, Henis M, Braren I, Kataria H, Sharaf A, Loers G, Schachner M, Lutz D (2018) A fragment of adhesion molecule L1 binds to nuclear receptors to regulate synaptic plasticity and motor coordination. Mol Neurobiol 55:7164-7178.
Sahu S, Zhang Z, Li R, Hu J, Shen H, Loers G, Shen Y, Schachner M (2018) A small organic compound mimicking the L1 cell adhesion molecule promotes functional recovery after spinal cord injury in zebrafish. Mol Neurobiol 55:859-878.
Katic J, Loers G, Tosic J, Schachner M, Kleene R (2017) The cell adhesion molecule CHL1 interacts with patched-1 to regulate apoptosis during postnatal cerebellar development. J Cell Sci. 130:2606-2619.
Loers G, Astafiev S, Hapiak Y, Saini V, Mishra B, Gul S, Kaur G, Schachner M, Theis T. (2017) The polysialic acid mimetics idarubicin and irinotecan stimulate neuronal survival and neurite outgrowth and signal via protein kinase C. J Neurochem 142:392-406.
Lutz D, Sharaf A, Drexler D, Kataria H, Wolters-Eisfeld G, Brunne B, Kleene R, Loers G, Frotscher M, Schachner M (2017) Proteolytic cleavage of transmembrane cell adhesion molecule L1 by extracellular matrix molecule Reelin is important for mouse brain development. Sci Rep 7:15268.
Westphal N, Loers G, Lutz D, Theis T, Kleene R, Schachner M (2017) Generation and intracellular trafficking of a polysialic acid-carrying fragment of the neural cell adhesion molecule NCAM to the cell nucleus. Sci Rep 7:8622.
Westphal N, Theis T, Loers G, Schachner M, Kleene R (2017) Nuclear fragments of the neural cell adhesion molecule NCAM with or without polysialic acid differentially regulate gene expression. Sci Rep 7:13631.