Selected Publications

Westphal, N., Theis, T., Loers, G., Schachner, M. & Kleene, R. (2017) Nuclear fragments of the neural cell adhesion molecule NCAM with or without polysialic acid differentially regulate gene expression. SCI REP-UK. 7, 1, S. 13631

Lutz, D., Sharaf, A., Drexler, D., Kataria, H., Wolters-Eisfeld, G., Brunne, B., Kleene, R., Loers, G., Frotscher, M. & Schachner, M. (2017) Proteolytic cleavage of transmembrane cell adhesion molecule L1 by extracellular matrix molecule Reelin is important for mouse brain development. SCI REP-UK. 7, 1, S. 1526

Lutz, D., Kataria, H., Kleene, R., Loers, G., Chaudhary, H., Guseva, D., Wu, B., Jakovcevski, I. & Schachner, M. (2016) Myelin Basic Protein Cleaves Cell Adhesion Molecule L1 and Improves Regeneration After Injury. MOL NEUROBIOL.53, 5, S. 3360-3376

Guitart, K., Loers, G., Buck, F., Bork, U., Schachner, M. & Kleene, R. (2016) Improvement of neuronal cell survival by astrocyte-derived exosomes under hypoxic and ischemic conditions depends on prion proteinGLIA. 64, 6, S. 896-910

Kleene, R., Chaudhary, H., Karl, N., Katic, J., Kotarska, A., Guitart, K., Loers, G., and Schachner, M. (2015) Interaction between the close homolog of L1 and serotonin receptor 2c regulates signal transduction and behavior in mice. J. Cell Sci. 15, 2816-2829.

Loers, G., Saini, V., Mishra, B., Gul, S., Chaudhury, S., Wallqvist, A., Kaur, G., and Schachner, M. (2015) Vinorelbine and epirubicin share common features with polysialic acid and modulate neuronal and glial functions. J. Neurochem. 2015 October 7 [Epub ahead of print].

Lutz, D., Kataria, H., Kleene, R., Loers, G., Chaudhary, H., Guseva, D., Wu, B., Jakovcevski, I., and Schachner, M. (2015) Myelin basic protein cleaves cell adhesion molecule L1 and improves regeneration after injury. Mol. Neurobiol. 2015 June 17 [Epub ahead of print].

Sauce, B., Wass, C., Netrakanti, M., Saylor, J., Schachner, M., and Matzel, L.D. (2015) Heterozygous L1-deficient mice express an autism-like phenotype. Behav. Brain Res. 432-442.

Schmalbach, B., Lepsveridze, E., Djogo, N., Papashvili, G., Kuang, F., Leshchyns'ka, I., Sytnyk, V., Nikonenko, A.G., Dityatev, A., Jakovcevski, I., and Schachner, M. (2015) Age-dependent loss of parvalbumin-expressing hippocampal interneurons in mice deficient in CHL1, a mental retardation and schizophrenia susceptibility gene. J. Neurochem. 4, 830-844.

Katic, J., Loers, G., Kleene, R., Karl, N., Schmidt, C., Buck, F., Zmijeqski, J.W., Jakovcevski, I., Preissner, K.T., and Schachner, M. (2014) Interaction of the cell adhesion molecule CHL1 with vitronectin, integrins, and the plasminogen activator inhibitor-2 promotes CHL1-induced neurite outgrowth and neuronal migration. J. Neurosci. 44, 14606-14623

Brandewiede, J., Stork, O., and Schachner, M. (2014) NCAM deficiency in the mouse forebrain impairs innate and learned avoidance behaviours. Genes Brain Behav. 5, 468-467.

Chipman, P.H., Schachner, M., and Rafuse, V.F. (2014) Presynaptic NCAM is required for motor neurons to functionally expand their peripheral field of innervation in partially denervated muscles. J. Neurosci. 6, 10497-10510.

Lutz, D., Loers, G., Kleene, R., Oezen, I., Kataria, H., Katagihallimath, N., Braren, I., Harauz, G., and Schachner, M. (2014) Myelin basic protein cleaves cell adhesion molecule L1 and promotes neuritogenesis and cell survival. J. Biol. Chem. 289, 13508-13518.

Xu, J.C., Xiao, M.F., Jakovcevski, I., Sivukhina, E., Hargus, G., Cui, Y.F., Irintchev, A., Schachner, M., and Bernreuther, C. (2014) The extracellular matrix glycoprotein tenascin-R regulates neurogenesis during development and in the adult dentate gyrus of mice. J. Cell Sci. 127, 641-652.

David, L.S., Schachner, M., and Saghatelyan, A. (2013). The extracellular matrix glycoprotein tenascin-R affects adult but not developmental neurogenesis in the olfactory bulb. J. Neurosci. 33, 10324-10339.

Djogo, N., Jakovcevski, I., Müller, C., Lee, H.J., Xu, J.C., Jakovcevski, M., Kügler, S., Loers, G., and Schachner, M. (2013). Adhesion molecule L1 binds to amyloid beta and reduces Alzheimer’s disease pathology in mice. Neurobiol. Dis. 56, 104-115.

Schmid, J.S., Bernreuther, C., Nikonenko, A.G., Ling, Z., Miles, G., Hossmann, K.A., Jakovcevski, I., and Schachner, M. (2013) Heterozygosity for the mutated X-chromosome-linked L1 cell adhesion molecule gene leads to increased numbers of neurons and enhanced metabolism in the forebrain of female carrier mice. Brain Struct. Funct. 218. 1375-1390.

Shetty, A., Sytnyk, V., Leshchyns’ka, I., Puchkov, D., Haucke, V., and Schachner, M. (2013). The neural adhesion molecule promotes maturation of the presynaptic endocytotic machinery by switching synaptic vesicle recycling from adaptor protein 3 (AP-3)- to AP-2-dependent mechanisms. J. Neurosci. 33, 16828-16845. IF 6.747

Stemmer, N., Strekalova, E., Djogo, N., Plöger, F., Loers, G., Lutz, D., Buck, F., Michalak, M., Schachner, M., and Kleene, R. (2013). Generation of amyloid-beta is reduced by the interaction of calreticulin with amyloid precursor protein, presenilin and nicastrin. PLoS One 8, e61299. IF 3.534

Theis, T., Mishra, B., von der Ohe, M., Loers, G., Prondzynski, M., Pless, O., Blackshear, P.J., Schachner, M., and Kleene, R. (2013). Functional role of the interaction between polysialic acid and myristoylated alanine-rich C kinase substrate at the plasma membrane. J. Biol. Chem. 288, 6726-6742.

Xie, K., Liu, Y., Hao, W., Walter, S., Penke, B., Hartmann, T., Schachner, M., and Fassbender, K. (2013). Tenascin-C deficiency ameliorates Alzheimer’s disease-related pathology in mice. Neurobiol. Aging 34, 2389-2398.

All Publicatons Melitta Schachner