Martin Aepfelbacher
Prof. Dr. med.
Martin Aepfelbacher
  • Facharzt für Mikrobiologie, Virologie und Infektionsepidemiologie
  • 1.Arbeitsbereich
Sprachen
Deutsch (Muttersprache)
Englisch

Fachgebiete

Tätigkeitsschwerpunkte

Lebenslauf

Publikationen

Zurück
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2011
  • 2010
  • 2009
  • 2008
  • 2007
  • 2006
Vor

Influence of local epidemiology on the performance of common colistin drug susceptibility testing methods
Asar L, Pfefferle S, Lütgehetmann M, Hoffmann A, Katchanov J, Aepfelbacher M, Rohde H, Maurer F
PLOS ONE. 2019;14(6):e0217468.

Nrf2 Sequesters Keap1 Preventing Podosome Disassembly:A Quintessential Duet Moonlights in Endothelium
Kloska D, Kopacz A, Cysewski D, Aepfelbacher M, Dulak J, Jozkowicz A, Grochot-Przeczek A
ANTIOXID REDOX SIGN. 2019;30(14):1709-1730.

Visualization of translocons in Yersinia type III protein secretion machines during host cell infection
Nauth T, Huschka F, Schweizer M, Bosse J, Diepold A, Failla A, Steffen A, Stradal T, Wolters M, Aepfelbacher M
PLOS PATHOG. 2018;14(12):e1007527.

Megahertz serial crystallography
Wiedorn M, Oberthür D, Bean R, Schubert R, Werner N, Abbey B, Aepfelbacher M, Adriano L, Allahgholi A, Al-Qudami N, Andreasson J, Aplin S, Awel S, Ayyer K, Bajt S, Barák I, Bari S, Bielecki J, Botha S, Boukhelef D, Brehm W, Brockhauser S, Cheviakov I, Coleman M, Cruz-Mazo F, Danilevski C, Darmanin C, Doak R, Domaracky M, Dörner K, Du Y, Fangohr H, Fleckenstein H, Frank M, Fromme P, Gañán-Calvo A, Gevorkov Y, Giewekemeyer K, Ginn H, Graafsma H, Graceffa R, Greiffenberg D, Gumprecht L, Göttlicher P, Hajdu J, Hauf S, Heymann M, Holmes S, Horke D, Hunter M, Imlau S, Kaukher A, Kim Y, Klyuev A, Knoška J, Kobe B, Kuhn M, Kupitz C, Küpper J, Lahey-Rudolph J, Laurus T, Le Cong K, Letrun R, Xavier P, Maia L, Maia F, Mariani V, Messerschmidt M, Metz M, Mezza D, Michelat T, Mills G, Monteiro D, Morgan A, Mühlig K, Munke A, Münnich A, Nette J, Nugent K, Nuguid T, Orville A, Pandey S, Pena G, Villanueva-Perez P, Poehlsen J, Previtali G, Redecke L, Riekehr W, Rohde H, Round A, Safenreiter T, Sarrou I, Sato T, Schmidt M, Schmitt B, Schönherr R, Schulz J, Sellberg J, Seibert M, Seuring C, Shelby M, Shoeman R, Sikorski M, Silenzi A, Stan C, Shi X, Stern S, Sztuk-Dambietz J, Szuba J, Tolstikova A, Trebbin M, Trunk U, Vagovic P, Ve T, Weinhausen B, White T, Wrona K, Xu C, Yefanov O, Zatsepin N, Zhang J, Perbandt M, Mancuso A, Betzel C, Chapman H, Barty A
NAT COMMUN. 2018;9(1):4025.

Acting on Actin:Rac and Rho Played by Yersinia
Aepfelbacher M, Wolters M
CURR TOP MICROBIOL. 2017;399:201-220.

Emergence of ceftazidime/avibactam non-susceptibility in an MDR Klebsiella pneumoniae isolate
Both A, Büttner H, Huang J, Perbandt M, Belmar Campos C, Christner M, Maurer F, Kluge S, König C, Aepfelbacher M, Wichmann D, Rohde H
J ANTIMICROB CHEMOTH. 2017;72(9):2483-2488.

Two-tier approach combining molecular and culture-based techniques for optimized detection of vancomycin-resistant enterococci
Both A, Franke G, Mirwald N, Lütgehetmann M, Christner M, Klupp E, Belmar Campos C, Büttner H, Aepfelbacher M, Rohde H
DIAGN MICR INFEC DIS. 2017;89(4):253-257.

Molecular analysis of the ramRA locus in clinical Klebsiella pneumoniae isolates with reduced susceptibility to tigecycline
Campos C, Aepfelbacher M, Hentschke M
NEW MICROBIOL. 2017;40(2):135-138.

p38(MAPK)/MK2-dependent phosphorylation controls cytotoxic RIPK1 signalling in inflammation and infection
Menon M, Gropengießer J, Fischer J, Novikova L, Deuretzbacher A, Lafera J, Schimmeck H, Czymmeck N, Ronkina N, Kotlyarov A, Aepfelbacher M, Gaestel M, Ruckdeschel K
NAT CELL BIOL. 2017;19(10):1248-1259.

Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells
Berneking L, Schnapp M, Rumm A, Trasak C, Ruckdeschel K, Alawi M, Grundhoff A, Kikhney A, Nolte F, Buck F, Perbandt M, Betzel C, Svergun D, Hentschke M, Aepfelbacher M
PLOS PATHOG. 2016;12(6):e1005660.

First report of Escherichia coli co-producing NDM-1 and OXA-232
Both A, Huang J, Kaase M, Hezel J, Wertheimer D, Fenner I, Günther T, Grundhoff A, Büttner H, Aepfelbacher M, Rohde H, Hentschke M
DIAGN MICR INFEC DIS. 2016;86(4):437-438.

Extended spectrum beta-lactamase producing Enterobacteriaceae causing bloodstream infections in rural Ghana, 2007-2012
Eibach D, Campos C, Krumkamp R, Al-Emran H, Dekker D, Boahen K, Kreuels B, Adu-Sarkodie Y, Aepfelbacher M, Park S, Panzner U, Marks F, May J
INT J MED MICROBIOL. 2016;306(4):249-54.

Tedizolid susceptibility in linezolid- and vancomycin-resistant Enterococcus faecium isolates
Klupp E, Both A, Belmar Campos C, Büttner H, König C, Christopeit M, Christner M, Aepfelbacher M, Rohde H
EUR J CLIN MICROBIOL. 2016;35(12):1957-1961.

Staphylococcus aureus recruits Cdc42GAP through recycling endosomes and the exocyst to invade human endothelial cells
Rauch L, Hennings K, Trasak C, Röder A, Schröder B, Nolte F, Rivera-Molina F, Toomre D, Aepfelbacher M
J CELL SCI. 2016;129(15):2937-49.

Tropheryma whipplei in children with diarrhoea in rural Ghana
Vinnemeier C, Klupp E, Krumkamp R, Rolling T, Fischer N, Owusu-Dabo E, Addo M, Adu-Sarkodie Y, Käsmaier J, Aepfelbacher M, Cramer J, May J, Tannich E
CLIN MICROBIOL INFEC. 2016;22(1):65.e1 - 65.e3.

Evaluation of Unbiased Next-Generation Sequencing of RNA (RNA-seq) as a Diagnostic Method in Influenza Virus-Positive Respiratory Samples
Fischer N, Indenbirken D, Meyer T, Lütgehetmann M, Lellek H, Spohn M, Aepfelbacher M, Alawi M, Grundhoff A
J CLIN MICROBIOL. 2015;53(7):2238-50.

Hepatitis E Virus
Pauli G, Aepfelbacher M, Bauerfeind U, Blümel J, Burger R, Gärtner B, Gröner A, Gürtler L, Heiden M, Hildebrandt M, Jansen B, Offergeld R, Schlenkrich U, Schottstedt V, Seitz R, Strobel J, Willkommen H, Baylis S
TRANSFUS MED HEMOTH. 2015;42(4):247-65.

Analysis of Yersinia enterocolitica Effector Translocation into Host Cells Using Beta-lactamase Effector Fusions.
Wolters M, Zobiak B, Nauth T, Aepfelbacher M
JOVE-J VIS EXP. 2015;(104):.

Prevalence and genotypes of extended spectrum beta-lactamases in Enterobacteriaceae isolated from human stool and chicken meat in Hamburg, Germany
Belmar Campos C, Fenner I, Wiese N, Lensing C, Christner M, Rohde H, Aepfelbacher M, Fenner T, Hentschke M
INT J MED MICROBIOL. 2014;304(5-6):678-684.

Rapid MALDI-TOF mass spectrometry strain typing during a large outbreak of Shiga-Toxigenic Escherichia coli
Christner M, Trusch M, Rohde H, Kwiatkowski M, Schlüter H, Wolters M, Aepfelbacher M, Hentschke M
PLOS ONE. 2014;9(7):e101924.

Rapid Metagenomic Diagnostics for Suspected Outbreak of Severe Pneumonia
Fischer N, Rohde H, Indenbirken D, Günther T, Reumann K, Lütgehetmann M, Meyer T, Kluge S, Aepfelbacher M, Alawi M, Grundhoff A
EMERG INFECT DIS. 2014;20(6):1072-5.

Improved Detection of Bacterial Central Nervous System Infections by Use of a Broad-Range PCR Assay
Meyer T, Franke G, Polywka S, Lütgehetmann M, Gbadamosi J, Magnus T, Aepfelbacher M
J CLIN MICROBIOL. 2014;52(5):1751-3.

Cell death triggered by Yersinia enterocolitica identifies processing of the proinflammatory signal adapter MyD88 as a general event in the execution of apoptosis
Novikova L, Czymmeck N, Deuretzbacher A, Buck F, Richter K, Weber A, Aepfelbacher M, Ruckdeschel K
J IMMUNOL. 2014;192(3):1209-19.

A role for exocyst in maturation and bactericidal function of staphylococci-containing endothelial cell phagosomes
Rauch L, Hennings K, Aepfelbacher M
TRAFFIC. 2014;15(10):1083-98.

Surveillanceberichte zu Erregern und Antibiotikaresistenzen - eine Empfehlung zur Standardisierung
Warnke P, Aepfelbacher M, Fickenscher H, Solbach W, Steinmetz I, Podbielski A
DEUT MED WOCHENSCHR. 2014;139(25-26):1377-82.

A culture-independent sequence-based metagenomics approach to the investigation of an outbreak of Shiga-toxigenic Escherichia coli O104:H4
Loman N, Constantinidou C, Christner M, Rohde H, Chan J, Quick J, Weir J, Quince C, Smith G, Betley J, Aepfelbacher M, Pallen M
JAMA-J AM MED ASSOC. 2013;309(14):1502-10.

Duration of fecal shedding of Shiga toxin-producing Escherichia coli O104:H4 in patients infected during the 2011 outbreak in Germany: a multicenter study
Vonberg R, Höhle M, Aepfelbacher M, Bange F, Belmar Campos C, Claussen K, Christner M, Cramer J, Haller H, Hornef M, Fickenscher H, Zimmermann-Fraedrich K, Knobloch J, Kühbacher T, Manns M, Nitschke M, Peters G, Pulz M, Rohde H, Roseland R, Sayk F, Schaumburg F, Schöcklmann H, Schubert S, Solbach W, Karch H, Suerbaum S
CLIN INFECT DIS. 2013;56(8):1132-40.

Cytotoxic necrotizing factor-Y boosts Yersinia effector translocation by activating Rac protein
Wolters M, Boyle C, Lardong K, Trülzsch K, Steffen A, Rottner K, Ruckdeschel K, Aepfelbacher M
J BIOL CHEM. 2013;288(32):23543-53.

Activity modulation of the bacterial Rho GAP YopE: an inspiration for the investigation of mammalian Rho GAPs.
Aepfelbacher M, Roppenser B, Hentschke M, Ruckdeschel K
EUR J CELL BIOL. 2011;90(11):951-954.

Destabilization of YopE by the Ubiquitin-Proteasome Pathway Fine-Tunes Yop Delivery into Host Cells and Facilitates Systemic Spread of Yersinia enterocolitica in Host Lymphoid Tissue.
Gaus K, Hentschke M, Czymmeck N, Novikova L, Trülzsch K, Valentin-Weigand P, Aepfelbacher M, Ruckdeschel K
INFECT IMMUN. 2011;79(3):1166-1175.

Emergence of carbapenemases in Gram-negative bacteria in Hamburg, Germany.
Hentschke M, Goritzka V, Belmar Campos C, Merkel P, Ilchmann C, Lellek H, Scherpe S, Aepfelbacher M, Rohde H
DIAGN MICR INFEC DIS. 2011;71(3):312-315.

CMY-42, a novel plasmid-mediated CMY-2 variant AmpC beta-lactamase.
Hentschke M, Kotsakis S, Wolters M, Heisig P, Miriagou V, Aepfelbacher M
MICROB DRUG RESIST. 2011;17(2):165-169.

Open-source genomic analysis of Shiga-toxin-producing E. coli O104:H4.
Rohde H, Qin J, Cui Y, Li D, Loman N, Hentschke M, Chen W, Pu F, Peng Y, Li J, Xi F, Li S, Li Y, Zhang Z, Yang X, Zhao M, Wang P, Guan Y, Cen Z, Zhao X, Christner M, Kobbe R, Loos S, Oh J, Yang L, Danchin A, Gao G, Song Y, Li Y, Yang H, Wang J, Xu J, Pallen M, Wang J, Aepfelbacher M, Yang R, Consortium E
NEW ENGL J MED. 2011;365(8):718-724.

Staphylococcus epidermidis uses distinct mechanisms of biofilm formation to interfere with phagocytosis and activation of mouse macrophage-like cells 774A.1.
Schommer N, Christner M, Hentschke M, Ruckdeschel K, Aepfelbacher M, Rohde H
INFECT IMMUN. 2011;79(6):2267-2276.

Organelle segregation into Plasmodium liver stage merozoites.
Stanway R, Mueller N, Zobiak B, Graewe S, Froehlke U, Zessin P, Aepfelbacher M, Heussler V
CELL MICROBIOL. 2011;13(11):1768-1782.

MALDI-TOF MS fingerprinting allows for discrimination of major methicillin-resistant Staphylococcus aureus lineages.
Wolters M, Rohde H, Maier T, Belmar Campos C, Franke G, Scherpe S, Aepfelbacher M, Christner M
INT J MED MICROBIOL. 2011;301(1):64-68.

Diagnosis of Toxoplasma gondii infection after allogeneic stem cell transplant can be difficult and requires intensive scrutiny.
Cavattoni I, Ayuketang Ayuk F, Zander A, Zabelina T, Bacher A, Cayiroglu E, Knospe V, Illies T, Aepfelbacher M, Richard G, Kröger N, Bacher U
LEUKEMIA LYMPHOMA. 2010;51(8):1530-1535.

The giant extracellular matrix-binding protein of Staphylococcus epidermidis mediates biofilm accumulation and attachment to fibronectin.
Christner M, Franke G, Schommer N, Wendt U, Wegert K, Pehle P, Kroll G, Schulze C, Buck F, Mack D, Aepfelbacher M, Rohde H
MOL MICROBIOL. 2010;75(1):187-207.

Rapid identification of bacteria from positive blood culture bottles by use of matrix-assisted laser desorption-ionization time of flight mass spectrometry fingerprinting.
Christner M, Rohde H, Wolters M, Sobottka I, Wegscheider K, Aepfelbacher M
J CLIN MICROBIOL. 2010;48(5):1584-1591.

Xenotropic murine leukemia virus-related gammaretrovirus in respiratory tract.
Fischer N, Schulz C, Stieler K, Hohn O, Lange C, Drosten C, Aepfelbacher M
EMERG INFECT DIS. 2010;16(6):1000-1002.

Epidemiology, variable genetic organisation and regulation of the EDIN-B toxin in Staphylococcus aureus from bacteraemic patients.
Franke G, Böckenholt A, Sugai M, Rohde H, Aepfelbacher M
MICROBIOL-SGM. 2010;156:860-872.

Yersinia virulence factor YopM induces sustained RSK activation by interfering with dephosphorylation.
Hentschke M, Berneking L, Campos C, Buck F, Ruckdeschel K, Aepfelbacher M
PLOS ONE. 2010;5(10):.

ramR mutations in clinical isolates of Klebsiella pneumoniae with reduced susceptibility to tigecycline.
Hentschke M, Wolters M, Sobottka I, Rohde H, Aepfelbacher M
ANTIMICROB AGENTS CH. 2010;54(6):2720-2723.

Host range and cellular tropism of the human exogenous gammaretrovirus XMRV.
Stieler K, Schulz C, Lavanya M, Aepfelbacher M, Stocking C, Fischer N
VIROLOGY. 2010;399(1):23-30.

Beta1 integrin-dependent engulfment of Yersinia enterocolitica by macrophages is coupled to the activation of autophagy and suppressed by type III protein secretion.
Deuretzbacher A, Czymmeck N, Reimer R, Trülzsch K, Gaus K, Hohenberg H, Heesemann J, Aepfelbacher M, Ruckdeschel K
J IMMUNOL. 2009;183(9):5847-5860.

Combined ramR mutation and presence of a Tn1721-associated tet(A) variant in a clinical isolate of Salmonella enterica Serovar Hadar resistant to Tigecycline.
Hentschke M, Christner M, Sobottka I, Aepfelbacher M, Rohde H
ANTIMICROB AGENTS CH. 2009.

Yersinia enterocolitica differentially modulates RhoG activity in host cells.
Roppenser B, Röder A, Hentschke M, Ruckdeschel K, Aepfelbacher M
J CELL SCI. 2009;122(5):696-705.

GFP-targeting allows visualization of the apicoplast throughout the life cycle of live malaria parasites.
Stanway R, Witt T, Zobiak B, Aepfelbacher M, Heussler V
BIOL CELL. 2009;101(7):415-430, 430.

Alteration of the parasite plasma membrane and the parasitophorous vacuole membrane during exo-erythrocytic development of malaria parasites.
Sturm A, Graewe S, Franke-Fayard B, Retzlaff S, Bolte S, Roppenser B, Aepfelbacher M, Janse C, Heussler V
PROTIST. 2009;160(1):51-63.

Prevalence of human gammaretrovirus XMRV in sporadic prostate cancer.
Fischer N, Hellwinkel O, Schulz C, Chun F, Huland H, Aepfelbacher M, Schlomm T
J CLIN VIROL. 2008;43(3):277-283.

Emergence of linezolid resistance in a methicillin resistant Staphylococcus aureus strain.
Hentschke M, Saager B, Horstkotte M, Scherpe S, Wolters M, Kabisch H, Grosse R, Heisig P, Aepfelbacher M, Rohde H
INFECTION. 2008;36(1):85-87.

Regulation of epidermal tight-junctions (TJ) during infection with exfoliative toxin-negative Staphylococcus strains.
Ohnemus U, Kohrmeyer K, Houdek P, Rohde H, Wladykowski E, Vidal S, Horstkotte M, Aepfelbacher M, Kirschner N, Behne M, Moll I, Brandner J
J INVEST DERMATOL. 2008;128(4):906-916.

Effector functions of pathogenic Yersinia species.
Aepfelbacher M, Trasak C, Ruckdeschel K
THROMB HAEMOSTASIS. 2007;98(3):521-529.

Expression and functional characterization of gfpmut3.1 and its unstable variants in Staphylococcus epidermidis.
Franke G, Dobinsky S, Mack D, Wang C, Sobottka I, Christner M, Knobloch J, Horstkotte M, Aepfelbacher M, Rohde H
J MICROBIOL METH. 2007;71(2):123-132.

Lactobacillus fermentum attenuates the proinflammatory effect of Yersinia enterocolitica on human epithelial cells.
Frick J, Schenk K, Quitadamo M, Kahl F, Köberle M, Bohn E, Aepfelbacher M, Autenrieth I
INFLAMM BOWEL DIS. 2007;13(1):83-90.

Serogroup-related escape of Yersinia enterocolitica YopE from degradation by the ubiquitin-proteasome pathway.
Hentschke M, Trülzsch K, Heesemann J, Aepfelbacher M, Ruckdeschel K
INFECT IMMUN. 2007;75(9):4423-4431.

Yersinia protein kinase YopO is activated by a novel G-actin binding process.
Trasak C, Zenner G, Vogel A, Yüksekdag G, Rost R, Haase I, Fischer M, Israel L, Imhof A, Linder S, Schleicher M, Aepfelbacher M
J BIOL CHEM. 2007;282(4):2268-2277.

Micromechanics of filopodia mediated capture of pathogens by macrophages.
Vonna L, Wiedemann A, Aepfelbacher M, Sackmann E
EUR BIOPHYS J BIOPHY. 2007;36(2):145-151.

The kinesin KIF1C and microtubule plus ends regulate podosome dynamics in macrophages.
Kopp P, Lammers R, Aepfelbacher M, Woehlke G, Rudel T, Machuy N, Steffen W, Linder S
MOL BIOL CELL. 2006;17(6):2811-2823.

The proteasome pathway destabilizes Yersinia outer protein E and represses its antihost cell activities.
Ruckdeschel K, Pfaffinger G, Trülzsch K, Zenner G, Richter K, Heesemann J, Aepfelbacher M
J IMMUNOL. 2006;176(10):6093-6102.

Live cell imaging of phagosome maturation in Staphylococcus aureus infected human endothelial cells: small colony variants are able to survive in lysosomes.
Schröder A, Kland R, Peschel A, von Eiff C, Aepfelbacher M
MED MICROBIOL IMMUN. 2006;195(4):185-194.

Staphylococcus aureus fibronectin binding protein-A induces motile attachment sites and complex actin remodeling in living endothelial cells.
Schröder A, Schröder B, Roppenser B, Linder S, Sinha B, Fässler R, Aepfelbacher M
MOL BIOL CELL. 2006;17(12):5198-5210.

Detection and genotyping of SHV beta-lactamase variants by mass spectrometry after base-specific cleavage of in vitro-generated RNA transcripts.
Stürenburg E, Storm N, Sobottka I, Horstkotte M, Scherpe S, Aepfelbacher M, Müller S
J CLIN MICROBIOL. 2006;44(3):909-915.

Letzte Aktualisierung aus dem FIS: 13.12.2019 - 00:38 Uhr