Johannes Kluwe
Priv.-Doz. Dr. med.
Johannes Kluwe
  • Facharzt für Innere Medizin und Gastroenterologie
  • 1.Arbeitsbereich
Sprachen
Deutsch (Muttersprache)

Fachgebiete

Tätigkeitsschwerpunkte

Auszeichnungen

Mitgliedschaften

Publikationen

Zurück
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011
  • 2010
  • 2009
  • 2007
Vor

Norursodeoxycholic acid versus placebo in the treatment of non-alcoholic fatty liver disease: a double-blind, randomised, placebo-controlled, phase 2 dose-finding trial

The lancet. Gastroenterology & hepatology. 2019;4(10):781-793.

Lactate Improves Prediction of Short-Term Mortality in Critically Ill Patients With Cirrhosis
Drolz A, Horvatits T, Rutter K, Landahl F, Roedl K, Meersseman P, Wilmer A, Kluwe J, Lohse A, Kluge S, Trauner M, Fuhrmann V
HEPATOLOGY. 2019;69(1):258-269.

Einsatz von Protonenpumpenhemmern bei Patienten mit Leberzirrhose – eine Umfrage unter Hepatologen in Deutschland
Horvatits T, Drolz A, Wehmeyer M, Steib C, Trebicka J, Lohse A, Kluwe J
Z GASTROENTEROL. 2019;57(6):729-733.

Transjugular Intrahepatic Portosystemic Shunt (TIPS) for primary and secondary prophylaxis of variceal bleeding in hepatic schistosomiasis
Kraef C, Arand J, Galaski J, Jordan S, Kluwe J, Lohse A, Addo M, Ramharter M, Schmiedel S
TRAVEL MED INFECT DI. 2019;30:130-132.

Ascites control by TIPS is more successful in patients with a lower paracentesis frequency and is associated with improved survival
Piecha F, Radunski U, Ozga A, Steins D, Drolz A, Horvatits T, Spink C, Ittrich H, Benten D, Lohse A, Sinning C, Kluwe J
JHEP Reports. 2019;2019(1):90-98.

Alcohol-related Liver Disease is Rarely Detected at Early Stages Compared With Liver Diseases of Other Etiologies Worldwide
Shah N, Ventura-Cots M, Abraldes J, Alboraie M, Alfadhli A, Argemi J, Badia-Aranda E, Soler E, Barritt A, Bessone F, Biryukova M, Carrilho F, Fernández M, Guiridi Z, El Kassas M, Eng-Kiong T, Farias A, George J, Gui W, Harichander-Thurairajah P, Hsiang J, Husić-Selimovic A, Isakov V, Karoney M, Kim W, Kluwe J, Kochhar R, Dhaka N, Costa P, Nabeshima M, Ono S, Reis D, Rodil A, Domech C, Sáez-Royuela F, Scheurich C, Siow W, Sivac-Burina N, Dos Santos Traquino E, Some F, Spreckic S, Tan S, Vorobioff J, Wandera A, Wu P, Yakoub M, Yang L, Yu Y, Zahiragic N, Zhang C, Cortez-Pinto H, Bataller R
CLIN GASTROENTEROL H. 2019;17(11):2320-2329.e12.

Heterozygous carriage of the alpha1-antitrypsin Pi*Z variant increases the risk to develop liver cirrhosis
Strnad P, Buch S, Hamesch K, Fischer J, Rosendahl J, Schmelz R, Brueckner S, Brosch M, Heimes C, Woditsch V, Scholten D, Nischalke H, Janciauskiene S, Mandorfer M, Trauner M, Way M, McQuillin A, Reichert M, Krawczyk M, Casper M, Lammert F, Braun F, von Schönfels W, Hinz S, Burmeister G, Hellerbrand C, Teufel A, Feldman A, Schattenberg J, Bantel H, Pathil A, Demir M, Kluwe J, Boettler T, Ridinger M, Wodarz N, Soyka M, Rietschel M, Weber T, Marhenke S, Vogel A, Hinrichsen H, Canbay A, Schlattjan M, Sosnowsky K, Sarrazin C, von Felden J, Geier A, Deltenre P, Sipos B, Schafmayer C, Nothnagel M, Aigner E, Datz C, Stickel F, Morgan M, Hampe J, Berg T, Trautwein C
GUT. 2019;68(6):1099-1107.

Could inherited predisposition drive non-obese fatty liver disease? Results from German tertiary referral centers.

J HUM GENET . 2018;63(5):621-626.

A humanized mouse model of liver fibrosis following expansion of transplanted hepatic stellate cells
Benten D, Kluwe J, Wirth J, Thiele N, Follenzi A, Bhargava K, Palestro C, Koepke M, Tjandra R, Volz T, Lutgehetmann M, Gupta S
LAB INVEST. 2018;98(4):525-536.

Severe Acute Liver Injury Following Therapeutic Doses of Acetaminophen in a Patient With Spinal Muscular Atrophy
Brehm T, Wehmeyer M, Fuhrmann V, Schäfer H, Kluwe J
AM J THER. 2018;26(4):e528-e529.

Kombination von NAFLD Fibrosis Score und transienter Elastografie zur Identifikation mittelgradiger Fibrosestadien (II/III) bei nicht-alkoholischer Fettlebererkrankung
Drolz A, Wehmeyer M, Diedrich T, Piecha F, Schulze Zur Wiesch J, Kluwe J
Z GASTROENTEROL. 2018;56(1):43-50.

Versorgung bei kompensierter Leberzirrhose 2018 – Evidenzbasierte prophylaktische Maßnahmen
Karkmann K, Piecha F, Rünzi A, Schulz L, von Wulffen M, Benten D, Kluwe J, Wege H
Z GASTROENTEROL. 2018;56(1):55-69.

Persistierender Aszites nach TIPS-Implantation ist prädiktiv für ein geringeres transplantationsfreies Überleben bei Patienten mit Leberzirrhose
Piecha F, Steins D, Drolz A, Wehmeyer M, Horvatits T, Spink C, Ittrich H, Lohse A, Kluwe J
2018. Abstractband GASL 2018. 2018. Aufl. Thieme Deutschlnad, .

Metabolic Circuit Involving Free Fatty Acids, microRNA 122, and Triglyceride Synthesis in Liver and Muscle Tissues
Chai C, Rivkin M, Berkovits L, Simerzin A, Zorde-Khvalevsky E, Rosenberg N, Klein S, Yaish D, Durst R, Shpitzen S, Udi S, Tam J, Heeren J, Worthmann A, Schramm C, Kluwe J, Ravid R, Hornstein E, Giladi H, Galun E
GASTROENTEROLOGY. 2017;153(5):1404-1415.

Gingival fibroblasts protect against experimental abdominal aortic aneurysm development and rupture through tissue inhibitor of metalloproteinase-1 production
Giraud A, Zeboudj L, Vandestienne M, Joffre J, Esposito B, Potteaux S, Vilar J, Cabuzu D, Kluwe J, Seguier S, Tedgui A, Mallat Z, Lafont A, Ait-Oufella H
CARDIOVASC RES. 2017;113(11):1364-1375.

The ABCB4 p.T175A variant as potential modulator of hepatic fibrosis in patients with chronic liver diseases: Looking beyond the cholestatic realm
Krawczyk M, Rau M, Grünhage F, Schattenberg J, Bantel H, Pathil A, Demir M, Kluwe J, Boettler T, Geier A, Lammert F
HEPATOLOGY. 2017;66(2):666-667.

Combined effects of the TM6SF2 rs58542926, PNPLA3 rs738409 and MBOAT7 rs641738 variants on NAFLD severity: multicentre biopsy-based study
Krawczyk M, Rau M, Schattenberg J, Bantel H, Pathil A, Demir M, Kluwe J, Boettler T, Lammert F, Geier A
J LIPID RES. 2017;58(1):247-255.

TIMP-1 is upregulated, but not essential in hepatic fibrogenesis and carcinogenesis in mice
Thiele N, Wirth J, Steins D, Koop A, Ittrich H, Lohse A, Kluwe J
SCI REP-UK. 2017;7(1):714.

Influence of Liver Disease on Perioperative Outcome After Bariatric Surgery in a Northern German Cohort
Wolter S, Duprée A, Coelius C, El Gammal A, Kluwe J, Sauer N, Mann O
OBES SURG. 2017;27(1):90-95.

Infections complicating severe alcoholic Hepatitis: Enterococcus species represent the most frequently identified pathogen
Beisel C, Blessin U, Schulze Zur Wiesch J, Wehmeyer M, Lohse A, Benten D, Kluwe J
SCAND J GASTROENTERO. 2016;51(7):807-13.

Inflammation-Induced Expression and Secretion of MicroRNA 122 Leads to Reduced Blood Levels of Kidney-derived Erythropoietin and Anemia
Rivkin M, Simerzin A, Zorde-Khvalevsky E, Chai C, Yuval J, Rosenberg N, Harari-Steinfeld R, Schneider R, Amir G, Condiotti R, Heikenwalder M, Weber A, Schramm C, Wege H, Kluwe J, Galun E, Giladi H
GASTROENTEROLOGY. 2016;151(5):999-1010.e3.

Nonalcoholic fatty liver disease is associated with excessive calorie intake rather than a distinctive dietary pattern
Wehmeyer M, Zyriax B, Jagemann B, Roth E, Windler E, Schulze Zur Wiesch J, Lohse A, Kluwe J
MEDICINE. 2016;95(23):e3887.

Arginine and NASH--do macrophages deliver the first hit?
Scheja L, Kluwe J
J HEPATOL. 2015;62(2):260-1.

First data concerning the medical supply of patients with non-alcoholic fatty liver disease in Germany - a survey in university hospital centers of hepatology
Weiss J, Rau M, Bantel H, Bock H, Demir M, Kluwe J, Krawczyk M, Pathil-Warth A, Schattenberg J, Tacke F, Roeb E, Geier A
Z GASTROENTEROL. 2015;53(6):562-7.

Genetic dissection of retinoid esterification and accumulation in the liver and adipose tissue
Wongsiriroj N, Jiang H, Piantedosi R, Yang K, Kluwe J, Schwabe R, Ginsberg H, Goldberg I, Blaner W
J LIPID RES. 2014;55(1):104-114.

Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice
Pradere J, Kluwe J, De Minicis S, Jiao J, Gwak G, Dapito D, Jang M, Günther N, Mederacke I, Friedman R, Dragomir A, Aloman C, Schwabe R
HEPATOLOGY. 2013;58(4):1461-73.

Induction of heme oxygenase 1 prevents progression of liver fibrosis in Mdr2 knockout mice
Barikbin R, Neureiter D, Wirth J, Erhardt A, Schwinge D, Kluwe J, Schramm C, Tiegs G, Sass G
HEPATOLOGY. 2012;55(2):553-62.

Induction of heme oxygenase 1 prevents progression of liver fibrosis in Mdr2 knockout mice.
Barikbin R, Neureiter D, Wirth J, Erhardt A, Schwinge D, Kluwe J, Schramm C, Tiegs G, Sass G
HEPATOLOGY. 2012;55(2):553-562.

Absence of hepatic stellate cell retinoid lipid droplets does not enhance hepatic fibrosis but decreases hepatic carcinogenesis
Kluwe J, Wongsiriroj N, Troeger J, Gwak G, Dapito D, Pradere J, Jiang H, Siddiqi M, Piantedosi R, O'Byrne S, Blaner W, Schwabe R
GUT. 2011;60(9):1260-8.

Modulation of hepatic fibrosis by c-Jun-N-terminal kinase inhibition.
Kluwe J, Pradere J, Gwak G, Mencin A, Samuele D, Osterreicher C, Colmenero J, Bataller R, Schwabe R
GASTROENTEROLOGY. 2010;138(1):347-359.

Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibrosis.
Samuele D, Seki E, Paik Y, Osterreicher C, Kodama Y, Kluwe J, Torozzi L, Miyai K, Benedetti A, Schwabe R, Brenner D
HEPATOLOGY. 2010;52(4):1420-1430.

Hepatic stellate cell lipid droplets: a specialized lipid droplet for retinoid storage.
Blaner W, O'Byrne S, Wongsiriroj N, Kluwe J, D'Ambrosio D, Jiang H, Schwabe R, Hillman E, Piantedosi R, Libien J
BBA-MOL CELL BIOL L. 2009;1791(6):467-473.

Toll-like receptors, wound healing, and carcinogenesis.
Kluwe J, Mencin A, Schwabe R
J MOL MED. 2009;87(2):125-138.

Toll-like receptors as targets in chronic liver diseases.
Mencin A, Kluwe J, Schwabe R
GUT. 2009;58(5):704-720.

Angiotensin-converting-enzyme 2 inhibits liver fibrosis in mice.
Osterreicher C, Taura K, Samuele D, Seki E, Penz-Osterreicher M, Kodama Y, Kluwe J, Schuster M, Oudit G, Penninger J, Brenner D
HEPATOLOGY. 2009;50(3):929-938.

CCR1 and CCR5 promote hepatic fibrosis in mice.
Seki E, Samuele D, Gwak G, Kluwe J, Inokuchi S, Bursill C, Llovet J, Brenner D, Schwabe R
J CLIN INVEST. 2009;119(7):1858-1870.

Gene expression profiles during hepatic stellate cell activation in culture and in vivo.
Samuele D, Seki E, Uchinami H, Kluwe J, Zhang Y, Brenner D, Schwabe R
GASTROENTEROLOGY. 2007;132(5):1937-1946.

TLR4 enhances TGF-beta signaling and hepatic fibrosis.
Seki E, Samuele D, Osterreicher C, Kluwe J, Osawa Y, Brenner D, Schwabe R
NAT MED. 2007;13(11):1324-1332.

Letzte Aktualisierung aus dem FIS: 18.11.2019 - 00:38 Uhr